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Goto Takayuki  後藤 崇之

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GOTO TAKAYUKI  後藤 崇之

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Researcher Number 90806605
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help 2021 – 2025: 京都大学, 医学研究科, 講師
2017 – 2021: 京都大学, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related / Urology
Except Principal Investigator
Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords
Principal Investigator
前立腺癌 / 去勢抵抗性前立腺癌 / 去勢抵抗性 / 患者由来ゼノグラフト / 相同組換え修復関連遺伝子 / CDK12 / PDX / PARP阻害薬 / ATM阻害薬 / CDK12異常前立腺癌 … More / 化合物スクリーニング / 創薬 / ドラッグスクリーニング / オルガノイド / ゼノグラフト / 多様性 / エンザルタミド / PDXモデル / バイオマーカー / 治療抵抗性 / プロテオミクス / 癌 / エンザルタミド抵抗性 / xenograft … More
Except Principal Investigator
前立腺癌 / ノビレチン / 空間遺伝子発現解析 / 単一細胞遺伝子発現解析 / 臓器特異的転移指向性 / 尿路性器癌 / 去勢抵抗性前立腺癌 / Cx43 / 間質性膀胱炎 / 尿路上皮 / コネキシン43 / シクロホスファミド / 神経内分泌化 / スクリーニング / 固形癌 / 神経内分泌前立腺癌 / 可塑性 / シンジェニックマウス / ゼノグラフト / 癌ニッチ / 癌免疫 / 腎癌 / 腫瘍間質相互作用 / 転移形成 / 薬剤抵抗性 / 患者癌組織由来ゼノグラフト / エクソソーム / 抗PD-1抗体 / 患者由来ゼノグラフト / ヒト化シンジェニックマウス / 腎細胞癌 / 免疫チェックポイント阻害剤 / 尿中揮発性有機化合物 / 質量分析 / 脂質過酸化反応 / 尿 / 脂質 / 概日リズム / フラボノイド系化合物 / 時計遺伝子 / 夜間頻尿 Less
  • Research Projects

    (12 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (21 People)
  •  去勢抵抗性前立腺癌患者由来前臨床モデルを用いたPARP阻害薬の新規治療対象の探索Principal Investigator

    • Principal Investigator
      後藤 崇之
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kyoto University
  •  去勢抵抗性前立腺癌のPARP阻害薬不応性に対する高用量アンドロゲン併用治療の開発

    • Principal Investigator
      砂田 拓郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kyoto University
  •  Establishment of a novel therapeutic strategy for progressive urogenital carcinoma focusing on the preferential metastasis mechanism

    • Principal Investigator
      松井 喜之
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      National Cancer Center Japan
  •  Establishment of genomic pathology based tumor subtyping system for solid cancers by single cell spatial transcriptome sequencing

    • Principal Investigator
      赤松 秀輔
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Nagoya University
  •  患者由来ゼノグラフトを用いたCDK12変異前立腺癌のPARP阻害薬不応性の克服Principal Investigator

    • Principal Investigator
      後藤 崇之
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kyoto University
  •  炎症性膀胱疾患における慢性炎症と尿路上皮ギャップ結合蛋白の関与の解明

    • Principal Investigator
      河野 仁
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kyoto University
  •  Development of innovative therapies for solid tumors by regulating plasticity

    • Principal Investigator
      Akamatsu Shusuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Nagoya University
      Kyoto University
  •  Establishment of an evaluation model for renal cancer immune niche replication and treatment using next-generation humanized syngeneic mice.

    • Principal Investigator
      Ogawa Osamu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kyoto University
  •  Drug screening using xenografts and organoids derived from castration-resistant prostate cancer patients.Principal Investigator

    • Principal Investigator
      Goto Takayuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kyoto University
  •  Elucidation of the bladder clock function using flavonoids and its application for timed therapy in nocturia patients

    • Principal Investigator
      ITO Haruki
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Department of Clinical Research, National Hospital Organization Kyoto Medical Center
  •  Investigation of novel prostate cancer diagnosis and treatment methods focusing lipid metabolism

    • Principal Investigator
      Inoue Takahiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Mie University
      Kyoto University
  •  Elucidation of the mechanism of resistance to new generation androgen receptor axis-targeted agents by using various patient-derived xenografts of prostate cancerPrincipal Investigator

    • Principal Investigator
      GOTO TAKAYUKI
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Urology
    • Research Institution
      Kyoto University

All 2021 2020 2019

All Journal Article Presentation Patent

  • [Journal Article] Establishment and characterization of a novel treatment-related neuroendocrine prostate cancer cell line KUCaP132021

    • Author(s)
      Kosuke Okasho, Takayuki Goto, Shusuke Akamatsu
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 7 Pages: 2781-2791

    • DOI

      10.1111/cas.14935

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19568
  • [Journal Article] A narrative review of urinary phospholipids: from biochemical aspect towards clinical application2021

    • Author(s)
      Xin Li, Kenji Nakayama, Takayuki Goto, Shusuke Akamatsu, Takashi Kobayashi, Koji Shimizu, Osamu Ogawa, Takahiro Inoue
    • Journal Title

      Translational Andrology and Urology.

      Volume: - Issue: 4 Pages: 1829-1849

    • DOI

      10.21037/tau-20-1263

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Journal Article] Data processing on a comparative evaluation of the extraction and analysis procedures for urinary phospholipid and lysophospholipid using MALDI-TOF/MS.2019

    • Author(s)
      Li X, Nakayama K, Goto T, Akamatsu S, Shimizu K, Ogawa O, Inoue T.
    • Journal Title

      Data Brief.

      Volume: 25 Pages: 1-6

    • DOI

      10.1016/j.dib.2019.104275

    • NAID

      120007153079

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Journal Article] Arteriovenous fistula after robot‐assisted laparoscopic prostatectomy: A rare case report2019

    • Author(s)
      Suzuki Ryosuke、Goto Takayuki、Kohno Shigeshi、Kita Yuki、Shimizu Hironori、Kobayashi Takashi、Yamasaki Toshinari、Ogawa Osamu、Inoue Takahiro
    • Journal Title

      IJU Case Reports

      Volume: Epub Issue: 4 Pages: 184-186

    • DOI

      10.1002/iju5.12072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Journal Article] Comparative evaluation of the extraction and analysis of urinary phospholipids and lysophospholipids using MALDI-TOF/MS2019

    • Author(s)
      Li Xin、Nakayama Kenji、Goto Takayuki、Akamatsu Shusuke、Shimizu Koji、Ogawa Osamu、Inoue Takahiro
    • Journal Title

      Chemistry and Physics of Lipids

      Volume: 223 Pages: 104787-104787

    • DOI

      10.1016/j.chemphyslip.2019.104787

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Journal Article] Consecutive Prostate Cancer Specimens Revealed Increased Aldo-Keto Reductase Family 1 Member C3 Expression with Progression to Castration-Resistant Prostate Cancer2019

    • Author(s)
      Miyazaki Yu、Teramoto Yuki、Shibuya Shinsuke、Goto Takayuki、Okasho Kosuke、Mizuno Kei、Uegaki Masayuki、Yoshikawa Takeshi、Akamatsu Shusuke、Kobayashi Takashi、Ogawa Osamu、Inoue Takahiro
    • Journal Title

      Journal of Clinical Medicine

      Volume: 8 Issue: 5 Pages: 601-601

    • DOI

      10.3390/jcm8050601

    • NAID

      120006709428

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Patent] 前立腺癌の判定法2019

    • Inventor(s)
      井上貴博、小川修、赤松秀輔、後藤崇之、李新、清水公治、中山憲司
    • Industrial Property Rights Holder
      井上貴博、小川修、赤松秀輔、後藤崇之、李新、清水公治、中山憲司
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2020
    • Data Source
      KAKENHI-PROJECT-18H02936
  • [Presentation] The Urinary Phosphatidylcholine/Lysophosphatidylcholine Ratio as a Novel Diagnostic Index for Prostate Cancer2020

    • Author(s)
      Xin Li, Kenji Nakayama, Takayuki Goto, Shusuke Akamatsu, Yujiro Hayashi, Kazutoshi Fujita, Takashi Kobayashi, Norio Nonomura, Osamu Ogawa, and Takahiro Inoue
    • Organizer
      第77回日本癌学会総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02936
  • 1.  Akamatsu Shusuke (20767248)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  澤田 篤郎 (10784796)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  中村 英二郎 (90293878)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  ITO Haruki (10817448)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Inoue Takahiro (80511881)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  Ogawa Osamu (90260611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  根来 宏光 (80708595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  奥野 博 (90263079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  坂根 直樹 (40335443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  清水 公治 (50395901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  加藤 学 (60626117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  佐々木 豪 (20644941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  中山 憲司 (30442594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 14.  山崎 俊成 (00607749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  嘉島 相輝 (50842952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  佐野 剛視 (60866309)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小林 恭 (00642406)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  河野 仁 (10880015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  砂田 拓郎 (50980281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  松井 喜之 (80817354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  都築 豊徳 (70627645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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