Goto Takayuki 後藤崇之

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GOTO TAKAYUKI 後藤崇之

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Researcher Number	90806605
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 講師
Affiliation (based on the past Project Information) *help	2021 – 2025: 京都大学, 医学研究科, 講師 2017 – 2021: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 前立腺癌 / 去勢抵抗性前立腺癌 / PARP阻害薬 / 去勢抵抗性 / 患者由来ゼノグラフト / 相同組換え修復関連遺伝子 / CDK12 / PDX / ATM阻害薬 / CDK12異常前立腺癌 … More / 化合物スクリーニング / 創薬 / ドラッグスクリーニング / オルガノイド / ゼノグラフト / 多様性 / エンザルタミド / PDXモデル / バイオマーカー / 治療抵抗性 / プロテオミクス / 癌 / エンザルタミド抵抗性 / xenograft … More Except Principal Investigator 前立腺癌 / ノビレチン / 空間遺伝子発現解析 / 単一細胞遺伝子発現解析 / 臓器特異的転移指向性 / 尿路性器癌 / 去勢抵抗性前立腺癌 / Cx43 / 間質性膀胱炎 / 尿路上皮 / コネキシン43 / シクロホスファミド / 神経内分泌化 / スクリーニング / 固形癌 / 神経内分泌前立腺癌 / 可塑性 / シンジェニックマウス / ゼノグラフト / 癌ニッチ / 癌免疫 / 腎癌 / 腫瘍間質相互作用 / 転移形成 / 薬剤抵抗性 / 患者癌組織由来ゼノグラフト / エクソソーム / 抗PD-1抗体 / 患者由来ゼノグラフト / ヒト化シンジェニックマウス / 腎細胞癌 / 免疫チェックポイント阻害剤 / 尿中揮発性有機化合物 / 質量分析 / 脂質過酸化反応 / 尿 / 脂質 / 概日リズム / フラボノイド系化合物 / 時計遺伝子 / 夜間頻尿 Less

去勢抵抗性前立腺癌患者由来前臨床モデルを用いたPARP阻害薬の新規治療対象の探索Principal Investigator
- Principal Investigator
  
  後藤崇之
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kyoto University
去勢抵抗性前立腺癌のPARP阻害薬不応性に対する高用量アンドロゲン併用治療の開発
- Principal Investigator
  
  砂田拓郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kyoto University
Establishment of a novel therapeutic strategy for progressive urogenital carcinoma focusing on the preferential metastasis mechanism
- Principal Investigator
  
  松井喜之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  National Cancer Center Japan
Establishment of genomic pathology based tumor subtyping system for solid cancers by single cell spatial transcriptome sequencing
- Principal Investigator
  
  赤松秀輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
患者由来ゼノグラフトを用いたCDK12変異前立腺癌のPARP阻害薬不応性の克服Principal Investigator
- Principal Investigator
  
  後藤崇之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kyoto University
炎症性膀胱疾患における慢性炎症と尿路上皮ギャップ結合蛋白の関与の解明
- Principal Investigator
  
  河野仁
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kyoto University
Development of innovative therapies for solid tumors by regulating plasticity
- Principal Investigator
  
  Akamatsu Shusuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
  Kyoto University
Establishment of an evaluation model for renal cancer immune niche replication and treatment using next-generation humanized syngeneic mice.
- Principal Investigator
  
  Ogawa Osamu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Drug screening using xenografts and organoids derived from castration-resistant prostate cancer patients.Principal Investigator
- Principal Investigator
  
  Goto Takayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Kyoto University
Elucidation of the bladder clock function using flavonoids and its application for timed therapy in nocturia patients
- Principal Investigator
  
  ITO Haruki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Investigation of novel prostate cancer diagnosis and treatment methods focusing lipid metabolism
- Principal Investigator
  
  Inoue Takahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Mie University
  Kyoto University
Elucidation of the mechanism of resistance to new generation androgen receptor axis-targeted agents by using various patient-derived xenografts of prostate cancerPrincipal Investigator
- Principal Investigator
  
  GOTO TAKAYUKI
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Urology
- Research Institution
  Kyoto University

All 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Establishment and characterization of a novel treatment-related neuroendocrine prostate cancer cell line KUCaP132021
- Author(s)
  Kosuke Okasho, Takayuki Goto, Shusuke Akamatsu
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 7 Pages: 2781-2791
- DOI
  10.1111/cas.14935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19568
[Journal Article] A narrative review of urinary phospholipids: from biochemical aspect towards clinical application2021
- Author(s)
  Xin Li, Kenji Nakayama, Takayuki Goto, Shusuke Akamatsu, Takashi Kobayashi, Koji Shimizu, Osamu Ogawa, Takahiro Inoue
- Journal Title
  
  Translational Andrology and Urology.
  
  Volume: - Issue: 4 Pages: 1829-1849
- DOI
  10.21037/tau-20-1263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02936
[Journal Article] Data processing on a comparative evaluation of the extraction and analysis procedures for urinary phospholipid and lysophospholipid using MALDI-TOF/MS.2019
- Author(s)
  Li X, Nakayama K, Goto T, Akamatsu S, Shimizu K, Ogawa O, Inoue T.
- Journal Title
  
  Data Brief.
  
  Volume: 25 Pages: 1-6
- DOI
  10.1016/j.dib.2019.104275
- NAID
  120007153079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02936
[Journal Article] Arteriovenous fistula after robot‐assisted laparoscopic prostatectomy: A rare case report2019
- Author(s)
  Suzuki Ryosuke、Goto Takayuki、Kohno Shigeshi、Kita Yuki、Shimizu Hironori、Kobayashi Takashi、Yamasaki Toshinari、Ogawa Osamu、Inoue Takahiro
- Journal Title
  
  IJU Case Reports
  
  Volume: Epub Issue: 4 Pages: 184-186
- DOI
  10.1002/iju5.12072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02936
[Journal Article] Comparative evaluation of the extraction and analysis of urinary phospholipids and lysophospholipids using MALDI-TOF/MS2019
- Author(s)
  Li Xin、Nakayama Kenji、Goto Takayuki、Akamatsu Shusuke、Shimizu Koji、Ogawa Osamu、Inoue Takahiro
- Journal Title
  
  Chemistry and Physics of Lipids
  
  Volume: 223 Pages: 104787-104787
- DOI
  10.1016/j.chemphyslip.2019.104787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02936
[Journal Article] Consecutive Prostate Cancer Specimens Revealed Increased Aldo-Keto Reductase Family 1 Member C3 Expression with Progression to Castration-Resistant Prostate Cancer2019
- Author(s)
  Miyazaki Yu、Teramoto Yuki、Shibuya Shinsuke、Goto Takayuki、Okasho Kosuke、Mizuno Kei、Uegaki Masayuki、Yoshikawa Takeshi、Akamatsu Shusuke、Kobayashi Takashi、Ogawa Osamu、Inoue Takahiro
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 8 Issue: 5 Pages: 601-601
- DOI
  10.3390/jcm8050601
- NAID
  120006709428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02936
[Patent] 前立腺癌の判定法2019
- Inventor(s)
  井上貴博、小川修、赤松秀輔、後藤崇之、李新、清水公治、中山憲司
- Industrial Property Rights Holder
  井上貴博、小川修、赤松秀輔、後藤崇之、李新、清水公治、中山憲司
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-18H02936
[Presentation] The Urinary Phosphatidylcholine/Lysophosphatidylcholine Ratio as a Novel Diagnostic Index for Prostate Cancer2020
- Author(s)
  Xin Li, Kenji Nakayama, Takayuki Goto, Shusuke Akamatsu, Yujiro Hayashi, Kazutoshi Fujita, Takashi Kobayashi, Norio Nonomura, Osamu Ogawa, and Takahiro Inoue
- Organizer
  第77回日本癌学会総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02936

1. Akamatsu Shusuke (20767248)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. 澤田篤郎 (10784796)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 中村英二郎 (90293878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ITO Haruki (10817448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Inoue Takahiro (80511881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. Ogawa Osamu (90260611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 根来宏光 (80708595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 奥野博 (90263079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坂根直樹 (40335443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 清水公治 (50395901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 加藤学 (60626117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐々木豪 (20644941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中山憲司 (30442594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 山崎俊成 (00607749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 嘉島相輝 (50842952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐野剛視 (60866309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小林恭 (00642406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 河野仁 (10880015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 砂田拓郎 (50980281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 松井喜之 (80817354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 都築豊徳 (70627645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 村上薫 (00977910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 齊藤亮一 (30792270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Goto Takayuki 後藤 崇之

GOTO TAKAYUKI 後藤 崇之

Research Projects

Research Products

Co-Researchers

去勢抵抗性前立腺癌患者由来前臨床モデルを用いたPARP阻害薬の新規治療対象の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

患者由来ゼノグラフトを用いたCDK12変異前立腺癌のPARP阻害薬不応性の克服Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug screening using xenografts and organoids derived from castration-resistant prostate cancer patients.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of resistance to new generation androgen receptor axis-targeted agents by using various patient-derived xenografts of prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment and characterization of a novel treatment-related neuroendocrine prostate cancer cell line KUCaP132021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A narrative review of urinary phospholipids: from biochemical aspect towards clinical application2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Data processing on a comparative evaluation of the extraction and analysis procedures for urinary phospholipid and lysophospholipid using MALDI-TOF/MS.2019

Goto Takayuki 後藤崇之

GOTO TAKAYUKI 後藤崇之