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ONO Teruo  小野 輝夫

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小野 輝夫  オノ テルオ

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Researcher Number 00000927
Affiliation (based on the past Project Information) *help 1992 – 1999: 新潟大学, 医学部, 教授
1990: 新潟大学, 医学部, 教授
1987 – 1988: Niigata University Professor, 医学部, 教授
1986: 新大, 医学部, 教授
Review Section/Research Field
Principal Investigator
General medical chemistry / 医薬分子機能学 / Laboratory medicine
Except Principal Investigator
Structural biochemistry / Circulatory organs internal medicine
Keywords
Principal Investigator
コレステロール / NF-Y / I-FABP / I-15P / H-FABP / スクアレン・エポキシダーゼ / D8S508 / スクアレン・エポキシダーゼ(SE) / LXR / オキシステロール … More / 核内レセプター / transcriptional regulation / cholesterol / squalene epoxidase / 転写調節 / SRE / スクアレンエポキシダーゼ / バイオセンサー / スクリーニング / 高脂血症 / 動脈硬化 / スクアレン / 阻害剤 / C-FABP / L-FABP / 心筋梗塞 / 脂肪酸結合蛋白(FABP) / Acyl CoA synthetase / Brain fatty acid binding protein (B-FABP) / Cardiac fatty acid binding protein (H-FBP) / Hepatic fatty acid binding protein (L-FABP) / DG-kinase(Diacylglycerol kinase) / アラキドン酸 / 内因性脂肪酸 / L-FABP(肝型脂肪酸結合蛋白) / ジアシルグリセロールキナーゼ / アシルCoA合成酸素 / 脳型脂肪酸結合蛋白(B-FABP) / 心筋型脂肪酸結合蛋白(H-FABP) / 肝型脂肪酸結合蛋白(L-FABP) / nuclear receptor / oxysterol / I-BABP / Lanosterol Synthase(LS) / 24(s),25-epoxycholesterol / 核内レセプター結合エレメント(LXRE,FXRE) / ヌクレアーオーファンレセプター(LXR,FXR,RXR) / 転写制御 / 核内レヤプター / 酸化ステロール / Oxysterol / Intranuclear Receptor / SE Functional Domain / Sterol Regulatroy Element (SRE) / Transcriptional Regulation / Langer-Giedion Syndrome / Squalene Epoxidase (SE) / スクアレンエポ キシダーゼ(SE) / SE機能ドメイン / ステロールレギュレトリーエレメント(SRE) / Langer-Giedeon症候群 / スクアレンエポキシダーゼ(SE) / membrane binding domain / transcription factor / SREBP (sterol regulatory element binding protein) / lanosterol synthase / 染色体8 / プロモーター領域 / 発現調節 / HeLa細胞 / 遺伝子構造(イントロン-エクソン構成) / 転写調整 / 膜結合領域 / 転写因子 / SREBP / ラノステロール合成酵素 / chromosome 8 q24.13 / gene expression / LDL-receptor / HMG-CoA reductase / benzophenone derivatives / squalene epoxidase(SE) / 染色体8q24.13 / 遺伝子発現 / LDL-レセプター / HMG-CoA還元酵素 / ベンゾフェノン誘導体 / エポキシダーゼ(SE) / Growth inhibition / Squalene synthase (SS) / Antifungal drug / Cloning / Inhibitor / Yeast transformant / Lanosterol synthase (LS) / Squalene epoxidase (SE) / 生育阻害 / スクアレン合成酵素(SS) / 抗真菌剤 / クローニング / 酵母トランスフォーマント / ラノステロール合成酵素(LS) / Fluorescent Fatty Acid / Ischaemic Intestinal Diseases / Diabetes Mellitus / Fatty Acid-Binding Protein (FABP) / ステロイド産生臓器 / 脂肪酸 / 蛍光脂肪酸プローブ / 虚血性腸疾患 / 糖尿病 / Serum Mark / Myocardial Infarct / Fatty Acid-Binding Protein / 血清マーカー / Rat / Flavoenzyme / Monooxygenase / Cholesterol / Sterol Regulatory Element(SRE) / Squalene Epoxidase / 酵母 / sterol regulatory element (SRE) / ラット / モノオキシゲナーゼ / フラビン酵素 / sterol regulatory element(SRE) / αzu-グロブリン / 腎臓 / 胃壁細胞 / 胃 / 肝臓 / 心筋 / 脂肪酸結合蛋白 / acylcoA synthetase / liver fatty acid binding protein(L-FABP) / heart fatty acid binaing ptotein(H-FABP) … More
Except Principal Investigator
ras / molecular chaperon / signal transduction / isoprenoid / protein modification / posttranslational lipid modification / Ras / 分子シャペロン / シグナル伝達 / イソプレノイド / 蛋白質のプレニル化 / 蛋白質の脂質修飾 / DNA cloning / inhibitors / atherosclerosis / gene / squalene epoxidase / cholesterol / 代謝阻害薬 / スクアレンエポキシダーゼ / コレステロール代謝 / DNAクローニング / 阻害薬 / 動脈硬化症 / 遺伝子 / スクアレン・エポキシダーゼ / コレステロール / リンパ節転移 / 脈管侵襲 / 患者予後 / 癌の発育・進展 / 漿膜下微少浸潤癌 / 固有筋層浸潤癌 / 粘膜内癌 / 胆嚢 Less
  • Research Projects

    (14 results)
  • Co-Researchers

    (28 People)
  •  Transcriptional Regulation of Cholesterol Biosynthetic Gene by Nuclear ReceptorsPrincipal Investigator

    • Principal Investigator
      SAKAKIBARA Jun, 小野 輝夫
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      NIIGATA UNIVERSITY
  •  Cholesterol biosynthesic enzymes and inborn errorsPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      General medical chemistry
    • Research Institution
      Niigata University
  •  Structure and Regulation of Cholesterol BiosynthesisPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Niigata University
  •  Cellular Signal Transduction by Isoprenoids

    • Principal Investigator
      FUJII Hiroshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Niigata University
  •  Regulatory mechanism of Enzymes of Cholesterol BiosynthesisPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Niigata University
  •  Development of A New Cholesterol Lowering Drug to Prevent Atherosclerosis

    • Principal Investigator
      OKAMOTO Hiroshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Hokkaido University
  •  REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTIONPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      NIIGATA UNIVERSITY
  •  Studies n Functional Roles of Fatty Acid-Binding ProteinsPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Niigata University
  •  REGULATION OF SQUALENE EPOXIDASE EXPRESSION AND THE ENZYME EVOLUTIONPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Niigata University
  •  DEVELOPMENT OF SERUM-FABP ASSAY AND IT'S CLINICAL APPLICATIONPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      NIIGATA UNIVERSITY
  •  ヒト胆道癌の発生・進展・特性に関する多角的基礎研究

    • Principal Investigator
      渡辺 英伸
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Niigata University
  •  心筋細胞での脂肪酸結合蛋白(FABP)の機能Principal Investigator

    • Principal Investigator
      小野 輝夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  心筋細胞での脂肪酸結合蛋白(FABP)の機能Principal Investigator

    • Principal Investigator
      小野 輝夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  Molecular species of fatty acid binding protein and their function in lipid metabolismPrincipal Investigator

    • Principal Investigator
      ONO Teruo
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Niigata University
  • 1.  SAKAKIBARA Jun (90242403)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  FUJII Hiroshi (90165340)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  ODANI Shoji (60018702)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KUMAGAI Hidetoshi (20281008)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  HITOMI Masahiro (40218730)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  WATANABE Michitoshi (40303127)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  星野 力 (30165542)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SCHROEPFER George
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OKADA Masahiko (30018915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISEKI Shoichi (50167251)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  SUZUKI Toshimitsu (80018952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KONDO Hisatake (20004723)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OKAMOTO Hiroshi (50260394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KAWAGUCHI Hideaki (70161297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KITABATAKE Akira (00124769)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KANOH Hideo (70045475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  渡辺 英伸 (70037381)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  木南 凌 (40133615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  STORCH Judith
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SHECHTER Ishaiahu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  PRESTWICH Glenn
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  JUDITH Storc
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  STEIN J.P.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  STEIN Joseph
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  LAW J.A
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SCHROPFER G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  EDWARDS P.A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  SHECHTER I
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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