• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

TAKEGUCHI Noriaki  竹口 紀晃

ORCIDConnect your ORCID iD *help
… Alternative Names

TAKEGUCHI Horiaki  竹口 紀晃

Less
Researcher Number 00019126
Affiliation (based on the past Project Information) *help 2002 – 2003: 富山医科薬科大学, 副学長
1993 – 2001: Toyama Meidcal and Pharmaceutical University Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授
1998: 富山医科歯科大学, 薬学部, 教授
1990 – 1991: 富山医科薬科大学, 薬学部, 教授
1986 – 1988: 富山医科薬科大学, 薬学部, 教授
1986: 富山医薬大, 薬学部, 教授
Review Section/Research Field
Principal Investigator
General physiology / Physical pharmacy / Biological Sciences
Except Principal Investigator
General physiology / Biological Sciences / General physiology
Keywords
Principal Investigator
胃酸分泌 / 胃プロトンポンプ / 塩素イオンチャネル / 細胞防御 / 大腸プロトンポンプ / プロトンポンプ阻害剤 / イオンポンプ / gastric acid secretion / Cl^-チャネル / 下痢 … More / パッチクランプ法 / Patch clamp / 単クローン抗体 / gastric proton pump / フリッパーゼ / 遺伝子発現 / ナトリウムポンプ / Gastric proton pump / Ion channel / 腸 / イオンチャネル / Cl^- channel / トロンボキサンA_2 / カンプトテシン / 制ガン剤 / 塩酸イリノテカン / GTP結合蛋白 / Antiporter / Pump / Second messenger / Epithelial transport / 小腸 / チャンネル / 細胞蛍光画像 / 胃 / チャネル / 細胞蛍光画像解析 / 上皮膜輸送 / 画像解析 / キャリア / アンチポーター / ポンプ / セカンドメッセンジャー / 上皮輸送 / C1^- channel / Monoclonal antibody / Gastric secretion / モノクローナル抗体 / イオンチャンネル / 胃液 / H,K-ATPase / Cl^-チャンネル / 胃酸 / nitric oxide / interleukin / cytoprotection / chloride channel / proton pump inhibitor / gastric flippase / 胃フリツパーゼ / 一酸化窒素 / インターロイキン / 胃フリッパーゼ / Na^+.K^+-ATPase / thromboxane / flippase / acid pump antagonist / proteasome / phosphorvlation / 大腸がん / 安定発現細胞 / 大腸 / 分子動力学 / リン脂質 / Na^+,K^+-ATPase / トロンボキサン / 酸分泌拮抗薬 / プロテアソーム / リン酸化 / Phospholipid / Flippase / Gastroenterology / Na pump / フォスフォリピッド / irinotecan / chloride ion secretion / thromboxane A_2 / diarrhed / anti-tumor drug / camptpothecin / 制癌剤 / トロンボキサンAX_2 / イリノテカン / トロンボキサンA2 / multidrug efflux pump / 多剤薬物排除ポンプ / Liver / Intestine / Diarrhea / Multi-drug efflux pump / 肝 / 解毒ポンプ / H^+, K^+-ATPase / proton pump / H^+,K^+ーATPase / プロトンポンプ / Cl^-チヤネル / オメプラゾール / H、K-ATPase / 胃flippase / 抗腫瘍剤 / cGMP / NO / プロスタグランジンE2 / 百日咳毒素 / ス-パオキシドアニオン / 胃酸分泌細胞 … More
Except Principal Investigator
イオンチャネル / EP / CLC-5 / ion channel / トランスポータ / ポンプ / トランスポーター / phosphorylation / molecular association / proton pump / chloride ion / gastric acid secretion / 細管小胞 / 胃酸分泌細胞 / 酵素活性 / 安定発現細胞 / イオン輸送 / 胃プロトンポンプ / 胃酸分泌機構 / リン酸化 / 分子会合 / プロトンポンプ / 塩素イオン / 胃酸分泌 / cloning / structure-function relation / Ca pump / transporter / water channel / クローニング / 構造・機能相関 / カルシウムポンプ / 水チャネル / 胃ベシクル / 閃光架橋法 / セチルコリン受容体 / 再構成ベシクル / 筋小胞体 / 脂質平面膜 / 膜小胞 / チャンネル / 免疫組織染色 / 遺伝子発現 / シクロオキシゲナーゼ / トロンボキサン合成酵素 / トロンボキサンレセプター / トロンボキサンA_2 / 高分化腺癌 / 大腸がん / 抗癌剤 / イオン / 膜輸送体 / 抗がん剤耐性 / 心臓 / 脳 / 糖尿病 / 電気生理学 / 分子生物学 / チャネル / ATP / キャリア Less
  • Research Projects

    (21 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (29 People)
  •  Novel physiological function of CLC-5 chloride channel associated with gastric proton pump

    • Principal Investigator
      SAKAI Hideki
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      University of Toyama
      Toyama Medical and Pharmaceutical University
  •  Structure and function of novel pumps and channels in gastrointestinal tractPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  大腸がん発症とトロンボキサンレセプター遺伝子発現異常の連関の分子生理学的研究

    • Principal Investigator
      酒井 秀紀
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Molecular and functional relations and intracellular polarized movement of the functional molecules in stomach and intestine.Principal Investigator

    • Principal Investigator
      SAKAI Hideki, 竹口 紀晃
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  化学療法剤による下痢発症機構と下痢抑制剤併用療法の基礎Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  フリッパーゼの機能-膜融合・細胞防御・時計側機能の可能性Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  The recognition and transport mechanism of ions in the proton pump and its intracellular transportPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General physiology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  化学療法剤による下痢発症機構と下痢抑制剤併用療法の基礎Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  細胞防御クロライドイオンチヤネルのGTP結合蛋白による調節Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  ATP駆動型トランスポータとチャネルの構造・機能協関

    • Principal Investigator
      UEDA Kazumitsu
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  Channel-Transporter Correlation

    • Principal Investigator
      OKADA Yasunobu
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okazaki National Research Institutes
  •  Electrophysiological study of the mechanism of diarrhea induced by camptothecin derivativePrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  細胞防御クロライドイオンチャネルのGTP結合蛋白による調節Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  イオンチャネルと担体型トランスポーターの構造的・機能的協関

    • Principal Investigator
      OKADA Yasunobu
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      General physiology
    • Research Institution
      Okazaki National Research Institutes
  •  Malfunction of liver and intestine ion channels in mutant ratsPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Physiological study of Cl^- channels associated with gastric proton pump and liver multidrug efflux pumpPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  Function, structure and regulation of two kinds of Cl^- channels involved in gastric acid secretionPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  H、K-ATPaseの高次構造Principal Investigator

    • Principal Investigator
      竹口 紀晃
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Studies of function of epithelial transport in single cellsPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Noriaki
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      General physiology
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  膜における情報変換分子の作動機構

    • Principal Investigator
      葛西 道生
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Osaka University
  •  Immuno-electrophysiologgy on ion channels in gastric secretory cellsPrincipal Investigator

    • Principal Investigator
      TAKEGUCHI Horiaki
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      TOYAMA MEDICAL AND PHAEMACEUTICAL UNIVERSITY

All 2005 2004 2002 2000

All Journal Article

  • [Journal Article] Cyclic AMP-dependent Cl^- secretion induced by thromboxane A_2 in isolated human colon.2005

    • Author(s)
      Horikawa N, Suzuki T, Uchiumi T, Minamimura T, Tsukada K, Takeguchi N, Sakai H.
    • Journal Title

      Journal of Physiology(London) 562巻3号

      Pages: 885-897

    • Data Source
      KAKENHI-PROJECT-15390062
  • [Journal Article] Novel molecular mechanisms of gastric phospholipids translocation activity in isolated hog gastric vesicles.2005

    • Author(s)
      Morii M, Sakai H, Takeguchi N.
    • Journal Title

      Membrane 30巻・6号

      Pages: 312-317

    • NAID

      10016855118

    • Data Source
      KAKENHI-PROJECT-15390062
  • [Journal Article] Effects of the anti-cancer drug gefitinib on Cl^- secretion in isolated rat colon.2005

    • Author(s)
      Ohkura J, Yamazaki H, Oyama Y, Morii M, Takeguchi N, Sakai H.
    • Journal Title

      J.Pharm.Soc.Jpn. 125巻

      Pages: 50-51

    • Data Source
      KAKENHI-PROJECT-15390062
  • [Journal Article] Cyclic AMP-dependent Cl^- secretion induced by thromboxane A_2 in isolated human colon.2005

    • Author(s)
      Horikawa N, Suzuki T, Uchiumi T, Minamimura T, Tsukada K, Takeguchi N, Sakai H.
    • Journal Title

      Journal of Physiology (London) 562巻3号

      Pages: 885-897

    • Data Source
      KAKENHI-PROJECT-12144205
  • [Journal Article] Is the ClC-2 chloride channel involved in the Cl^- secretory mechanism of gastric parietal cells?2004

    • Author(s)
      Hori K, Takahashi Y, Horikawa N, Furukawa T, Tsukada K, Takeguchi N, Sakai H.
    • Journal Title

      FEBS Letters 575巻1-3号

      Pages: 105-108

    • Data Source
      KAKENHI-PROJECT-15390062
  • [Journal Article] Is the ClC-2 chloride channel involved in the Cl^- secretory mechanism of gastric parietal cells?2004

    • Author(s)
      Hori K, Takahashi Y, Horikawa N, Furukawa T, Tsukada K, Takeguchi N, Sakai H.
    • Journal Title

      FEBS Letters 575巻1-3号

      Pages: 105-108

    • Data Source
      KAKENHI-PROJECT-12144205
  • [Journal Article] Up-regulation of Na^+,K^+-ATPase α3-isoform and down-regulation of the α1-isoform in human colorectal cancer.2004

    • Author(s)
      Sakai H, Suzuki T, Maeda M, Takahashi Y, Horikawa N, Minamimura T, Tsukada K, Takeguchi N.
    • Journal Title

      FEBS Letters 563巻1-3号

      Pages: 151-154

    • Data Source
      KAKENHI-PROJECT-15390062
  • [Journal Article] Up-regulation of Na^+, K^+-ATPase α3-isoform and down-regulation of the α1-isoform in human colorectal cancer.2004

    • Author(s)
      Sakai H, Suzuki T, Maeda M, Takahashi Y, Horikawa N, Minamimura T, Tsukada K, Takeguchi N.
    • Journal Title

      FEBS Letters 563巻1-3号

      Pages: 151-154

    • Data Source
      KAKENHI-PROJECT-12144205
  • [Journal Article] The cavity structure for docking the K^+-competitive inhibitors in the gastric proton pump.2004

    • Author(s)
      Asano S, Yoshida A, Yashiro H, Kobayashi Y, Morisato A, Ogawa H, Takeguchi N, Morii M.
    • Journal Title

      Journal of Biological Chemistry 279巻14号

      Pages: 13968-13975

    • Data Source
      KAKENHI-PROJECT-12144205
  • [Journal Article] Expression of ATP1AL1, a non-gastric proton pump, in human colorectum.2002

    • Author(s)
      Takahashi Y, et al.Tsukada K, Asano S, Takeguchi N
    • Journal Title

      Jpn J Physiol 52

      Pages: 317-321

    • NAID

      10010020642

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144205
  • [Journal Article] Establishment and characterization of a colonic epithelial cell line MCE301 from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene.2000

    • Author(s)
      Tabuchi Y, et al., Furusawa M, Obinata M, Fuse H, Takeguchi N, Asano S
    • Journal Title

      Cell Struct Funct 25

      Pages: 297-307

    • NAID

      10006679009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12144205
  • 1.  SAKAI Hideki (60242509)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 8 results
  • 2.  ASANO Shinji (90167891)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  IMAI Masashi (40049010)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MORII Magotoshi (60019130)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  五十里 彰
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  OKADA Yasunobu (10025661)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  UEDA Kazumitsu (10151789)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  HOSHI Takeshi (60004537)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MARUMO Fumiaki (00050443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TSUCHIYA Tomofusa (80012673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HATANAKA Yasumaru (30111181)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TASHIRO Yutaka (40077558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NISHIYAMA Akinori (90004556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KANNO Tomuo (50009982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  野間 昭典 (00132738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  北里 宏 (20079700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  山岸 俊一 (70014032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  堀江 稔 (90183938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  倉智 嘉久 (30142011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  赤池 紀生 (30040182)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  秋山 伸一 (60117413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  鈴木 裕一 (50091707)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  内藤 幹彦 (00198011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  田内 克典 (60260551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  葛西 道生 (40022595)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  加茂 直樹 (10001976)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  今栄 康雄 (70022712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  曽我部 正博 (10093428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  DIENER Martin
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi