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SHIMONISHI Yasutsugu  下西 康嗣

ORCIDConnect your ORCID iD *help
Researcher Number 00029951
Affiliation (based on the past Project Information) *help 1996 – 1997: 大阪大学, 蛋白質研究所, 教授
1992 – 1994: Osaka University, Institute for Protein Research Professor, 蛋白質研究所, 教授
1990 – 1992: 大阪大学, たんぱく質研究所, 教授
1986 – 1988: Institue for Protein Research, Osaka University, 蛋白質研究所, 教授
Review Section/Research Field
Principal Investigator
物質生物化学 / 有機化学一般
Except Principal Investigator
細菌学 / Structural biochemistry / Pathological medical chemistry / Bioorganic chemistry / Bacteriology (including Mycology)
Keywords
Principal Investigator
MS / タンデム質量分析計 / Long-acting agonist / Disulfide linkages / Heat-stable enterotoxin / Enterotoxigenic Escherichia coli / 毒性発現構造 / 活性持続型アゴニスト / ジスルフィド結合 / 耐熱性エンテロトキシン … More / 毒素原性大腸菌 / Femtomole / MS sequencing / Sample lifetime / Initial ionization event / Function generator / Four-sector tandem mass spectrometer / Array detector / Pulsed FAB / 高感度測定 / アレイ検出器 / 質量分析 / 蛋白質構造解析 / MSスペクトル / 高感度質量分析 / パルスイオン化 / イオン銃 / 糖鎖構造解析 / 糖ペプチド / アレイ型検出器 / フェムトモル / イオン化効率 / パルスイオン化法 / 高エネルギー粒子 / Peptide And Protein Sequencing / Stable-isotope Labeling of peptides / Fragment Ions / Multi-precursor lons / Digital Analog Converters / Acquisition Processor Unit / CPU-controlled MS / Four-sector Tandem mass spectrometer / マスクロマトグラム表示 / マススペクトル表示 / マルチプリカ-サ-イオン捕促システム / 自動制御システム / 安定同位体 ^<18>O標識化 / フラグメントイオンの分析 / 質量分析によるアミノ酸配列決定 / 安定同位体 ^<18>0標識化 / 衝突活性化開裂 / 質量校正用標準物質 / 磁場強度補正 / 前駆イオンの自動捕捉 / 磁場スウィッチング / タンデム質量分析用制御システム … More
Except Principal Investigator
細菌毒素 / 生体細胞情報 / enterotoxigenic Escherichia coli / Chemically synthesized ST / ELISA / competitive ELISA / 化学合成ST / 毒素原性大腸菌 / Biological modifier / Bacterial lipopolysaccharide / Bacterial toxin / 耐熱性毒素 / 下痢原因毒素 / 生物反応修飾物質 / 細菌内毒素 / Mass spectrometry / Gas-assisted flow machinery / Specific chemical cleavage / Protein primary structure / Gas-phase chemical reaction / Anticorrosive system / Microanalysis / 質量分析 / マルチ試料プレート / 耐蝕・耐圧性反応槽 / 特異的化学分解 / 気相化学反応装置 / アミノ酸配列 / 微量蛋白質 / Geranylgeranylzation / Processing / Amidation / Cystine protease / Glycation / システィンプロテア-ゼ / ゲラニルゲラニル化 / プロセシング / アミド化 / システィンプロテアーゼ / 糖化 / 重点領域 / 分子設計 / 構造活性相関 / ペプチド三次構造 / 生体内信号 / ペプチド合成 / ペプチド科学 / 生体機能性ペプチド / Vero毒素 / コレラ毒素 / モジュレイション / 蛋白毒素 / LPS / マクロファージ / GPIアンカー / 宿主細胞因子 / 感染 / 情報モジュレイション Less
  • Research Projects

    (10 results)
  • Co-Researchers

    (26 People)
  •  Development of a Full-Automatic Equipment for Gas-Phase Chemical Reaction Intended for Microanalysis of Protein Primary Structures

    • Principal Investigator
      TAKAO Toshifumi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Osaka University
  •  機能性ペプチドの分子設計における新展開

    • Principal Investigator
      宗像 英輔
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      University of Tsukuba
  •  病原微生物由来物質による生体細胞情報のモジュレイション

    • Principal Investigator
      竹田 美文
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kyoto University
  •  微生物由来物質による生体細胞情報のモジュレイション

    • Principal Investigator
      TAKEDA Yoshifumi
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      細菌学
    • Research Institution
      Kyoto University
  •  A New Pulsed FAB Control System Coupled with an Array Detector on a Four-Sector Tandem Mass SpectrometerPrincipal Investigator

    • Principal Investigator
      SHIMONISHI Yasutsugu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  The post-translational modification of proteins

    • Principal Investigator
      TANIGUCHI Naoyuki
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  A Control System for a Four-Sector Tandem Mass SpectrometerPrincipal Investigator

    • Principal Investigator
      SHIMONISHI Yasutsugu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Institute for Protein Research, Osaka University
  •  Studies of the Tertiary Structure and Structural Requirements for Toxic Expression of Heat-stable Enterotoxins Produced by Enterotoxigenic Escherichia coliPrincipal Investigator

    • Principal Investigator
      SHIMONISHI Yasutsugu
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      有機化学一般
    • Research Institution
      Osaka University
  •  Development of an ELISA Kit to detect ST produced by enterotoxigenic Esherichia coli by using chemically synthesized antigens.

    • Principal Investigator
      TAKEDA Yoshifumi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      細菌学
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  Studies on biological modifier produced by bacteria

    • Principal Investigator
      TAKEDA Yoshifumi
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
      Osaka University
  • 1.  TAKEDA Yoshifumi (30029772)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  TAKAO Toshifumi (10197048)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  浜田 茂幸 (60028777)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  吉川 昌之介 (80012714)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  森 良一 (50038692)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KAMMEI Yoshihiro
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TANIGUCHI Naoyuki (90002188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  OOMURA Tsuneo (80029933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OHKUBO Iwao (80152073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TASHIRO Yutaka (40077558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MAKITA Akira (60004561)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IMAMOTO Naoko (20202145)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HONDA Takeshi (60029808)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ARAI Tadashi (30009419)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NAKANO Masayasu (70048958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KATO Iwao (40012702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TAKEDA Tae (40112065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  木下 タロウ (10153165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  寺脇 良郎 (10014333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  宗像 英輔 (60072766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  藤井 信孝 (60109014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  木曾 良明 (40089107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  大野 素徳 (30038434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  塩入 孝之 (20012627)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  勝沼 信彦 (50035375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  FUKUDA Hiroyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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