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YOSHIHARA Shinichi  吉原 新一

ORCIDConnect your ORCID iD *help
… Alternative Names

YOSHIHARA/SHIN'ICHI  吉原 新一

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Researcher Number 00037607
Other IDs
Affiliation (based on the past Project Information) *help 2004: 広島国際大学, 薬学部, 教授
2002 – 2003: 広島大学, 大学院・医歯薬学総合研究科, 助教授
1998 – 2001: 広島大学, 医学部, 助教授
1986 – 1987: 広島大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Environmental pharmacy / Science and Engineering
Except Principal Investigator
Neurochemistry/Neuropharmacology / 医薬分子機能学 / Biological pharmacy / Environmental pharmacy / Science and Engineering
Keywords
Principal Investigator
アルキルフェノール / 異物(薬物)代謝酵素 / 異物代謝酵素 / ビスフェノールA / 代謝的活性化 / エストロゲン活性 / Biochanin A / Genistein / Alkylphenols / Bisphenol A … More / Metabolic activation / Xenobiotic metabolizing enzymes / Estrogenicity / Endocrine disrupting chemicals / オクチルフェノール / 内分泌撹乱化学物質 / ラット肝S9 / ヒトP450 / バイオカニンA / ゲニステイン / 内分泌攪乱化学物質 / 大豆イソフラボン / 内分泌攪乱物質 / 2-ニトロフルオレン / フェンチオン / プロエストロゲン / 抗アンドロゲン活性 / ベンゾフェノン類 / アルキルフェノール類 / 異物代謝 / 内分泌撹乱物質 … More
Except Principal Investigator
Parkinson's disease / パーキンソン病 / ドーパミン神経 / パーキンソン病発症物質 / テトラヒドロイソキノリン / 1MeTIQ / Parkinson's disease causing substance / tetrahydroisoquinoline / 細胞培養 / パーキンソン病防御物質 / 内分泌撹乱物質 / guinea pig / rabbit / drug-reducing activity / drug metabolism / flavin enzyme / aldehyde oxidase / new electron transfer system / menadione / N-アリル脂肪族ヒドロキサム酸 / 酵素阻害 / ヒドロキサム酸還元 / lipoamide dehydrogenase / xanthine cehydrogenace / 薬物代謝 / lipoamide clehydrogenase / NADPH-cytochrome c reductase / xanthine oxidase / アルデヒド酸化酵素 / フラビン酵素 / 新電子伝達系 / structure-activity relationship / anti-parkinsonian drug / tetrahydroisogunoline / 細胞培養系 / ミトコンドリア呼吸鎖阻害 / 1ベンジルTIQ / パーキンソニズム / 代謝変換 / サルゾリノール / cDNA microaray / apoptosis / differential display / neurotoxin / アポトーシス / NMDAレセプター / テトラハイドロイソキノリン / アポトーシス関連遺伝子 / cDNAマイクロアレイ / ディファレンシャルディスプレイ / 神経毒 / drug metabolizing enzyme / biphenyl / trans-stilbene / vitellogenin / metabolic activation / estrogen / proestrogen / endocrine disruptor / トランスースチルベンオキシド / トランス-スチルベン / ビテロゲニン / ビフェニール / トランスースチルベン / 薬物代謝酵素 / 代謝的活性化 / エストロゲン / 内分泌撹乱前駆物質 / aldehydeoxidase / early marker / アルデヒドオキシダーゼ / アルデヒドオキシターゼ / 早期診断技術 / cell culture / dopaminergic neuron / Parkinson's disease cpreventing substance / DNAマイクロアレイ / バイオアッセイ / 人体影響 / バイオアッセイ・バイオマーカー / 代謝機構 / 野生生物汚染 / 人体汚染 / 毒性メカニズム / 国際シンポジウム / 環境リスク Less
  • Research Projects

    (9 results)
  • Research Products

    (1 results)
  • Co-Researchers

    (14 People)
  •  Development of anti-parkinsonian drug using structure-activity relationship

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  内分泌攪乱物質並びにその前駆物質の代謝変換とホルモン作用の修飾Principal Investigator

    • Principal Investigator
      吉原 新一
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hiroshima University
  •  内分泌攪乱物質の環境リスク

    • Principal Investigator
      松井 三郎
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kyoto University
  •  Research for the Parkinson's disease related proteins using endogenous neurotoxins

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Metabolic Modulation of Estrogenicity of Endocrine Disrupting Chemicals by Cytochrome P450 in Human and Rat LiversPrincipal Investigator

    • Principal Investigator
      YOSHIHARA Shin'ichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Metabolism and endocrine disrupting action of environmental pollutants

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University School of Medicine
  •  Investigation of Parkinson's disease causing substances

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Hiroshima University
  •  Early markers of Parkinson's disease

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Hiroshima University
  •  Studies on Intra-cellular New Electron Transfer Systems Containing Aldehyde Oxidase as a Component.

    • Principal Investigator
      TATSUMI Kiyoshi
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY

All 2005

All Journal Article

  • [Journal Article] Comparative Study of the Endocrine-disrupting Activity of Bisphenol A and 19 Related Compounds.2005

    • Author(s)
      S.Kitamura, S.Yoshihara, et al.
    • Journal Title

      Toxicological Sciences (In press)

    • Data Source
      KAKENHI-PROJECT-12055101
  • 1.  KITAMURA Shigeyuki (40136057)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  SUGIHARA Kazumi (20271067)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  OHTA Shigeru (60160503)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  ARIZONO Koji (70128148)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  松井 三郎 (90092808)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  森 千里 (90174375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  田辺 信介 (60116952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  井口 泰泉 (90128588)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  森澤 眞輔 (50026340)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  NAKAMURA Shigenobu (30026843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  WATANABE Hiromitu (00034653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YAMASAKI Kazuo (00034017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOTAKE Yaichiro (20335649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TATSUMI Kiyoshi (90037581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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