kitamura shigeyuki 北村繁幸

… Alternative Names

Researcher Number	40136057
Other IDs
External Links
Affiliation (Current)	2020: 日本薬科大学, 薬学部, 客員教授
Affiliation (based on the past Project Information) *help	2017 – 2018: 日本薬科大学, 薬学部, 客員教授 2006 – 2016: Nihon Pharmaceutical University, Professor, 薬学部, 教授 2002 – 2005: Hiroshima University Graduate School of Biomedical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 1998 – 2001: 広島大学, 医学部, 助教授 1987: Research Assistant, Hiroshima University School of Medicine, 医学部, 助手
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Environmental pharmacy / Environmental pharmacy / Risk sciences of radiation/Chemicals Except Principal Investigator Risk sciences of radiation/Chemicals / Environmental pharmacy / Medical pharmacy / 医薬分子機能学 / Neurochemistry/Neuropharmacology / Science and Engineering / Biological pharmacy
Keywords	Principal Investigator 代謝的活性化 / ブロム化難燃剤 / 内分泌撹乱 / 水酸化代謝物 / 甲状腺ホルモン / 核内受容体 / 内分泌撹乱作用 / Endocrine disruptor / Metabolic activation / 甲状腺ホルモン撹乱 … More Except Principal Investigator パーキンソン病 / Parkinson's disease / 内分泌かく乱物質 / 医薬品 / 環境汚染 / テトラヒドロイソキノリン / パーキンソン病発症物質 / ドーパミン神経 / 内分泌攪乱物質 / 甲状腺ホルモン / 生態毒性 / 医療薬学 / ニコチン製剤 / aldehyde oxidase / 禁煙治療 / パーキンソン病防御物質 / 細胞培養 / tetrahydroisoquinoline / Parkinson's disease causing substance / 神経毒 / 1MeTIQ / 内分泌撹乱物質 / エストロゲン活性 / 異物代謝 / 代謝的活性化 / ビスフェノールA / アルキルフェノール類 / ベンゾフェノン類 / 抗アンドロゲン活性 / プロエストロゲン / 異物代謝酵素 / フェンチオン / 2-ニトロフルオレン / 異物(薬物)代謝酵素 / アルキルフェノール / 大豆イソフラボン / 子供の環境リスク / 甲状腺ホルモン応答遺伝子 / 発達期影響 / 新生児期曝露 / プロム化難燃剤 / 甲状腺ホメオスタシス / ブロム化難燃剤 / 太陽光 / 紫外線 / 環境因子 / 変異原性 / 東アジア / 医薬品汚染 / 大韓民国 / 生態系毒性 / 環境動態 / 環境保全リーダー育成 / 下垂体甲状腺系 / 肝臓 / 臭素化難燃剤 / 新生児期影響 / 遺伝子発現 / 新生児影響 / nicotine / CYP2A6 / ニコチン / 薬物代謝酵素 / Parkinson's disease cpreventing substance / dopaminergic neuron / cell culture / 早期診断技術 / アルデヒドオキシターゼ / アルデヒドオキシダーゼ / early marker / aldehydeoxidase / ディファレンシャルディスプレイ / cDNAマイクロアレイ / アポトーシス関連遺伝子 / テトラハイドロイソキノリン / NMDAレセプター / アポトーシス / neurotoxin / differential display / apoptosis / cDNA microaray / ダイオキシン / 副腎皮質ホルモン / 内分泌撹乱化学物質 / 糖質コルチコイド / Dioxin / Adrenal cortex hormone / Endocrine disrupters / Glucocorticoid / サルゾリノール / 代謝変換 / パーキンソニズム / 1ベンジルTIQ / ミトコンドリア呼吸鎖阻害 / 細胞培養系 / tetrahydroisogunoline / anti-parkinsonian drug / structure-activity relationship / テトラヒドロイソキノリン類 / P糖タンパク質 / 遺伝子発現調節 / テトラヒドロイソキノリン酸 / tetrahydroisoguinoline / P-glycoprotein / drug transporter / expression level / マウス / 前立腺 / 前立腺タンパク質 / エストロゲン受容体プロモーター / ベンゾフェノン / 臭素系難燃剤 / 発生異常 / mouse / prostate / prostatic proteins / estrogen receptor promoter / endocrine disruptors / benzophenones / brominated flame retardants / 病院下水 / 下水処理 / 生態影響 / Pharmaceuticals / Environmental pollution / Hospital sewage / Effect to ecosystem / 新電子伝達系 / フラビン酵素 / アルデヒド酸化酵素 / xanthine oxidase / NADPH-cytochrome c reductase / lipoamide clehydrogenase / 薬物代謝 / xanthine cehydrogenace / lipoamide dehydrogenase / ヒドロキサム酸還元 / 酵素阻害 / N-アリル脂肪族ヒドロキサム酸 / menadione / new electron transfer system / flavin enzyme / drug metabolism / drug-reducing activity / rabbit / guinea pig / nicotine製剤 / 投与設計 / 薬学 / 代謝酵素 Less

Influence of chemicals used in consumer products on endocrine-system via activation of nuclear receptorsPrincipal Investigator
- Principal Investigator
  
  Kitamura Shigeyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nihon Pharmaceutical University
Appropriate administration of nicotine according to the metabolic enzyme activity estimated from the nicotine metabolites in saliva.
- Principal Investigator
  
  Tayama yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima International University
Estimation of target proteins of hydroxylated PCB and brominated flame retardants for thyroid hormone disruption and the influence by radiationPrincipal Investigator
- Principal Investigator
  
  Kitamura Shigeyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nihon Pharmaceutical University
Estimation for the adequate dose of nicotine by using the ratio of the metabolites in urine
- Principal Investigator
  
  Tayama Yoshitaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hiroshima International University
Determination of targets for thyroid hormone disruption by brominated flame retardantsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nihon Pharmaceutical University
Quantitative analysis of neonatal exposure to thyroid hormone disrupting chemicals
- Principal Investigator
  
  FUJIMOTO Nariaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
Study of PPCPs in Eastern Asian countries
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima International University
Effects of neonatal exposure to thyroid hormone disrupting chemicals in rats
- Principal Investigator
  
  FUJIMOTO Nariaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
Study of environmental pollution by pharmaceuticals and effect of environmental factors on the toxicity.
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University
Formation of Hydroxylated Metabolites Responsible for the Toxicity of Brominated Flame Retardants and Thyroid Hormone Disrupting ActionPrincipal Investigator
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon Pharmaceutical University
Effects of low-dose endocrine disruptors on neonatal prostatic development
- Principal Investigator
  
  FUJIMOTO Nariaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Hiroshima University
Pharmaceuticals in hospital sewages and their toxicities to ecosystem
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Parkinsonism-inducing mechanism by endogenous multifunctional neurotoxins in the brain
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Thyroid hormone-disrupting activity of brominated retardants and hydroxylated PCBsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Development of anti-parkinsonian drug using structure-activity relationship
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  HIROSHIMA UNIVERSITY
内分泌攪乱物質並びにその前駆物質の代謝変換とホルモン作用の修飾
- Principal Investigator
  
  YOSHIHARA Shinichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hiroshima University
Metabolic activation of endocrine-disruptors in animal bodyPrincipal Investigator
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY
Effect of Dioxin and Endocrine disrupters on Adrenal Hormone
- Principal Investigator
  
  SUGIHARA Kazumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Hiroshima University
Research for the Parkinson's disease related proteins using endogenous neurotoxins
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  HIROSHIMA UNIVERSITY
Metabolism and endocrine disrupting action of environmental pollutantsPrincipal Investigator
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Environmental pharmacy
- Research Institution
  Hiroshima University School of Medicine
Investigation of Parkinson's disease causing substances
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Hiroshima University
Early markers of Parkinson's disease
- Principal Investigator
  
  OHTA Shigeru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Hiroshima University
Studies on Intra-cellular New Electron Transfer Systems Containing Aldehyde Oxidase as a Component.
- Principal Investigator
  
  TATSUMI Kiyoshi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HIROSHIMA UNIVERSITY

[Book] 光老化科学の最前線（第２３章紫外線吸収剤の代謝を介した核内受容体活性の発現）2015
- Author(s)
  渡部容子，北村繁幸（監修　前田憲寿）
- Total Pages
  301
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-25340049
[Book] 紫外線吸収剤の代謝を介した核内受容体活性の発現，光老化化学の最前線2015
- Author(s)
  北村繁幸, 渡部容子
- Publisher
  株式会社シーエムシー出版
- Data Source
  KAKENHI-PROJECT-25340049
[Book] 衛生薬学－健康と環境―2013
- Author(s)
  北村繁幸
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-22510071
[Book] Organophocphates as endocrine disruptors' in 'Anticholinesterase Pesticides'2011
- Author(s)
  Kitamura, Shigeyuki; Sugihara, Kazumi; Fujimoto, Nariaki; Yamazaki, Takeshi
- Publisher
  Wiley Edited by Satoh, Tetsuo : Gupta, Ramesh C
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Anticholinesterase Pesticides : Organophosphates as Endocrine Disruptors2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  21
- Publisher
  John Wiley & Sons, Ltd, Hoboken
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  14
- Publisher
  Johan Wiley and Sons Ltd.
- Data Source
  KAKENHI-PROJECT-20590122
[Book] Organophosphates as Endocrine Disruptor in Anticholinesterase pesticides2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Total Pages
  14
- Publisher
  Johan Wiley and Sons Ltd.
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Organophosphates as endocrine disruptors. Anticholinesterase pesticides : Metabolism, nurotoxicity and epidemiology.2010
- Author(s)
  Kitamura, et al
- Publisher
  John Wiley & Sons, Inc.
- Data Source
  KAKENHI-PROJECT-22510071
[Book] in Anticholinesterase pesticides.(Organophosphates as Endocrine Disruptor)2010
- Author(s)
  Kitamura S., Sugihara K., Fujimoto N., Yamazaki T.
- Total Pages
  14
- Publisher
  Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-20590122
[Book] T. Satoh, R. C. Gupta(ed.) Anticholinesterase Pesticides, John Wiley & Sons, Ltd, Hoboken, NJ2010
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
- Publisher
  Organophosphates asendocrine disruptors In
- Data Source
  KAKENHI-PROJECT-20510065
[Book] General and Applied Toxicology III Endocrine Disruption in Toxic Responses2009
- Author(s)
  Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
- Total Pages
  44
- Publisher
  John Wiley & Sons, Ltd, Chichester
- Data Source
  KAKENHI-PROJECT-20510065
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
- Total Pages
  15
- Publisher
  Johan Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
- Total Pages
  15
- Publisher
  Johan Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-20590122
[Book] the 3rd Edition of General and Applied Toxicology(Endocrine Disruption in Toxic Responses.)(In Ballantyne Bryan (ed))2009
- Author(s)
  Kitamura Shigeyuki ; Sueihara Kazumi ; Nakamura Kazuo ; Yaichiro Kotake ; Kashiwagi Akihiko ; Fujimoto Nariaki
- Publisher
  Wiley and Sons Ltd
- Data Source
  KAKENHI-PROJECT-20590122
[Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009
- Author(s)
  Kitamura, Shigeyuki ; Sugihara, Kazumi ; Nakamura, Kazuo ; Yaichiro Kotake ; Kashiwagi, Akihiko ; Fujimoto, Nariaki
- Data Source
  KAKENHI-PROJECT-21406005
[Book] Endocrine Disruption in Toxic Responses, B. Ballantyne, T. Marrs, T. Syversen(ed.) General and AppliedToxicology III, John Wiley & Sons, Ltd, Chichester2009
- Author(s)
  Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
- Data Source
  KAKENHI-PROJECT-20510065
[Book] THYROID HORMONAL AND ESTROGENIC ACTIVITIES OF HYDROXYLATED PCB AND BROMINATED FLAME RETARDANT IN CELL CULTURE2008
- Author(s)
  Kitamura Shigeyuki, et al.
- Publisher
  JME, POPs in Asia
- Data Source
  KAKENHI-PROJECT-20590122
[Book] THYROID HORMONAL AND ESTROGENIC ACTIVITIES OF HYDROXYLATED PCB AND BROMINATED FLAME RETARDANT IN CELL CULTURE, JME2008
- Author(s)
  Kitamura Shigeyuki, Sugihara, Kazumi, et al.
- Publisher
  POPS in Asia
- Data Source
  KAKENHI-PROJECT-20590122
[Book] Toxicology of Organophosphate and Carbamate Compounds (Endocrine disruption by organophosphate and carbamate pesticides)2006
- Author(s)
  Kitamura et al.分担(R.C.Gupta編集)
- Total Pages
  763
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-18590118
[Book] Endocrine Disruption by organophosphate and Carbamate pesticides In : Toxicology of organophosphate and carbamate compounds(R.C.Gupta(ed.)2006
- Author(s)
  Kitamura S.
- Total Pages
  14
- Publisher
  Elsevier Academic Press, London
- Data Source
  KAKENHI-PROJECT-17510046
[Book] Toxicology of Organophosphate and Carbamate Compounds2006
- Author(s)
  Kitamura, Shigeyuki, et al.
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-17590102
[Book] Toxicology of Organophosphate and Carbamate Compounds2006
- Author(s)
  Kitamura, Shigeyuk, etal.
- Publisher
  Academic Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Book] Toxicology of Organophosphate and Carbamate Compounds (Endocrine disruption by organophosphate and carbamate pesticides)2005
- Author(s)
  Kitamura et al.分担(R.C.Gupta編集)
- Total Pages
  763
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17590102
[Book] Toxicology of Organophosphate and Carbamate Compounds (Endocrine disruption by organophosphate and carbamate pesticides)2005
- Author(s)
  Kitamura et al.分担(R.C.Gupta編集)
- Total Pages
  763
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-16590092
[Book] Endocrine Disruption by organophosphate and Carbamate pesticides In:R.C.Gupta(ed.)Toxicology of organophosphate and carbamate compounds2005
- Author(s)
  Kitamura, S., Sugihara, K., Fujimoto, N.
- Publisher
  Elsevier Academic Press,London
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Book] Toxicology of Organophosphate and Carbamate Compounds(Endocrine disruption by organophosphate and carbamate pesticides)2005
- Author(s)
  Kitamura et al.分担(R.C.Gupta編集)
- Total Pages
  763
- Publisher
  Elsevier
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Book] Toxicology of Organophosphate and Carbamate Compounds (Endocrine disruption by organophosphate and carbamate pesticides)2005
- Author(s)
  Kitamura et al.(R.C.Gupta ed.)
- Publisher
  Elsevier
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Profiling of bisphenol A and eight of its analogues on transcriptional activity via human nuclear receptors2019
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Seigo Sanoh, Katsuhiro Okuda, Shigeyuki Kitamura, Naoto Uramaru, Kazumi Sugihara, Kouichi Yoshinari
- Journal Title
  
  Toxicology
  
  Volume: 413 Pages: 48-55
- DOI
  10.1016/j.tox.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17K15493, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-16K00559
[Journal Article] Effects of benzotriazole ultraviolet stabililizers on rat PXR, CAR and PPARa transcriptional activities2019
- Author(s)
  Yoko Watanabe, Shoko Hattori, Chieri Emori, Ken Tachibana, Hiroyuki Kojima, Kouichiro Yoshinari, Shigeyuki Kitamura
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 6 Pages: 57-63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Identification of hepatic thyroid hormone-responsive genes in neonatal rats: Potential targets for thyroid hormone-disruptinh chemicals2018
- Author(s)
  Fujimoto N., Kitamura S., Uramaru N., Miyagawa S., Iguchi T.
- Journal Title
  
  Toxicol. Lett.
  
  Volume: 286 Pages: 48-53
- DOI
  10.1016/j.toxlet.2018.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15493, KAKENHI-PLANNED-17H06432, KAKENHI-PROJECT-15H04396, KAKENHI-PROJECT-26440173, KAKENHI-PROJECT-18H02474, KAKENHI-PROJECT-16K00559
[Journal Article] Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactionsl2018
- Author(s)
  Naoki Takaoka; Seigo Sanoh; Katsuhiro Okuda; Yaichiro Kotake; Go Sugahara; Ami Yanagi; Yuji Ishida; Chise Tateno;Yoshitaka Tayama; Kazumi Sugihara; Shigeyuki Kitamura; Mami Kurosaki; Mineko Terao; Enrico Garattini; Shigeru Ohta
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 154 Pages: 28-38
- DOI
  10.1016/j.bcp.2018.04.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-16K00559
[Journal Article] Construction of the Database of Rat Repeated-dose Toxicity Tests of Pesticides for the Toxicological Characterization of Hepatocyte Hypertrophy2018
- Author(s)
  増田茜、増田雅美、中島宏之、小島弘幸、北村繁幸、浦丸直人、保坂卓臣、佐々木崇光、吉成浩一―
- Journal Title
  
  薬学雑誌
  
  Volume: 137 Issue: 5 Pages: 611-622
- DOI
  10.1248/yakushi.16-00259
- NAID
  130005631433
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-30
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K15493
[Journal Article] Aryl Hydrocarbon Receptor Ligand Activity of Extracts from 62 Herbal Medicines and Effect on Cytochrome P450 Activity2018
- Author(s)
  Harada A., Sugihara K., Watanabe Y., Yamaji S., Kitamura S., Ohta S.
- Journal Title
  
  薬学雑誌
  
  Volume: 135 Issue: 10 Pages: 1185-1196
- DOI
  10.1248/yakushi.15-00153
- NAID
  130005100636
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-31
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Study of metabolic activation of the UV-filter octyl methoxycinnamate for endocrine-disrupting activity2018
- Author(s)
  Yoko Watanabe, Chieri Emori, Naoto Uramaru, Nariaki Fujimoto, Shigeyuki Kitamura
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 5 Pages: 185-193
- NAID
  130007525309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Effect of the Metabolic Modification of Environmental Chemicals on Endocrine-disrupting Activity2018
- Author(s)
  Shigeyuki Kitamura
- Journal Title
  
  薬学雑誌
  
  Volume: 138 Issue: 5 Pages: 693-713
- DOI
  10.1248/yakushi.17-00214
- NAID
  130006729462
- ISSN
  0031-6903, 1347-5231
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Developmental changes in drug-metabolizing enzyme expression during metamorphosis of Xenopus tropicalis 2017
- Author(s)
 Mori J., Sanoh S., Kashiwagi K., Hanada H., Shigeta M., Suzuki K., Yamamoto T., Kotake Y., Sugihara K., Kitamura S., Kashiwagi A., Ohta S.
- Journal Title
 
 J. Toxicol. Sci.
 
 Volume: 42 Issue: 5 Pages: 605-613
- DOI
 10.2131/jts.42.605
- NAID
 130006076698
- ISSN
 0388-1350, 1880-3989
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17J02822
[Journal Article] Altered expression of the Olr59, Ethe1, and Slc10a2 genes in the liver of F344 rats by neonatal thyroid hormone disruption.2017
- Author(s)
  Matsubara K et al.
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: - Pages: 1030-1035
- DOI
  10.1002/jat.3452
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440173, KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K15493, KAKENHI-PLANNED-17H06432, KAKENHI-PROJECT-15H04396
[Journal Article] Comparative study of hydrolytic metabolism of dimethyl phthalate, dibutyl phthalate and di(2-ethylhexyl) phthalate by microsomes of various rat tissues2017
- Author(s)
  Ozaki H., Sugihara K., Watanabe Y., Moriguchi K., Uramaru N., Sone T., Ohta S., Kitamura S.
- Journal Title
  
  Food Chem Toxicol.
  
  Volume: 100 Pages: 217-224
- DOI
  10.1016/j.fct.2016.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
[Journal Article] Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene2017
- Author(s)
  Tanoue C., Sugihara K., Tayama Y., Uramaru N., Watanabe Y., Ohta S., Kitamura S.
- Journal Title
  
  Drug Metab Lett.
  
  Volume: 10 Pages: 278-285
- DOI
  10.2174/1872312810666161227145358
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
[Journal Article] Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products2016
- Author(s)
  Hitomi Ozaki, Kazumi Sugihara, Yoko Watanabe, Shigeru Ohta, Shigeyuki Kitamura　.
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 41 Issue: 4 Pages: 551-560
- DOI
  10.2131/jts.41.551
- NAID
  130005165024
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Estimation of occupational exposure to drugs during tablet crushing2016
- Author(s)
  Shizuko Maeda , Eiko Takahashi , Yoshitaka Tayama , Shigeyuki Kitamura , Toyohisa Tsukamoto , Katsushi Miyake , Kazumi Sugihara
- Journal Title
  
  Fundam. Toxicol. Sci.
  
  Volume: 3 Issue: 4 Pages: 177-183
- DOI
  10.2131/fts.3.177
- NAID
  130005158221
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460247, KAKENHI-PROJECT-16K08428
[Journal Article] In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities.2016
- Author(s)
  Tange S., Fujimoto N., Uramaru N., Wong F. F., Sugihara K., Ohta S., Kitamura S.
- Journal Title
  
  Environ Toxicol Pharmacol.
  
  Volume: 41 Pages: 289-297
- DOI
  10.1016/j.etap.2015.08.014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-16K00559
[Journal Article] Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities2016
- Author(s)
  Chieri Fujino, Yuki Tamura, Satoko Tange, Hiroyuki Nakajima, Seigo Sanoh, Yoko Watanabe, Naoto Uramaru, Hiroyuki Kojima, Kouichi Yoshinari, Shigeru Ohta, Shigeyuki Kitamura
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 41 Issue: 5 Pages: 677-691
- DOI
  10.2131/jts.41.677
- NAID
  130005266225
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-16K00559
[Journal Article] Estimation of occupational exposure to drugs during tablet crushing.2016
- Author(s)
  Shizuko Maeda, Eiko Takahashi, Yoshitaka Tayama, Shigeyuki Kitamura, Toyohisa Tsukamoto, Katsushi Miyake, Kazumi Sugihara.
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 3 Pages: 177-183
- NAID
  130005158221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00559
[Journal Article] Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy.2015
- Author(s)
  Sanoh, S., Tayama Y., Sugihara K., Kitamura S., Ohta S.
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 30 Pages: 52-63
- DOI
  10.1016/j.dmpk.2014.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Hydrolytic metabolism of phenyl and benzyl salicylates, fragrances and flavoring agents in foods, by microsomes of rat and human tissues2015
- Author(s)
  Ozaki H., Sugihara K., Tamura Y., Fujino C., Watanabe Y., Uramaru N., Sone T., Ohta S., Kitamura S.
- Journal Title
  
  Food Chem Toxicol
  
  Volume: 86. Pages: 116-123
- DOI
  10.1016/j.fct.2015.08.024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Predictability of plasma concentration-time curves in humans using single-species allometric scaling of chimeric mice with .humanized liver2015
- Author(s)
  Sanoh S., Naritomi Y., Fujimoto M., Sato K., Kawamura A., Horiguchi A., Sugihara K., Kotake Y., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S.
- Journal Title
  
  Xenobiotica
  
  Volume: 45 Pages: 605-614
- DOI
  10.3109/00498254.2015.1007112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.2015
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Seigo Sanoh, Kazumi Sugihara, Shigeyuki Kitamura, and Shigeru Ohta
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 282 Pages: 119-128
- DOI
  10.1016/j.taap.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] Basic Principles of Interpretation of Hepatocellular Hypertrophy in Risk Assessment in Japan2015
- Author(s)
  Yoshida M., Umemura T., Kojima H., Inoue K., Takahashi M., Uramaru N., Kitamura S., Abe K., Tohkin M., Ozawa S., Yoshinari K.,
- Journal Title
  
  Food Hyg. Saf. Sci.
  
  Volume: 56 Issue: 2 Pages: 42-48
- DOI
  10.3358/shokueishi.56.42
- NAID
  130005067294
- ISSN
  0015-6426, 1882-1006
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] Current stutus of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver2014
- Author(s)
  Kitamura S. and Sugihara K.
- Journal Title
  
  Xenobiotica
  
  Volume: 44 Pages: 123-134
- DOI
  10.3109/00498254.2013.868062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] Transesterification of a series of 12 parabens by liver and small-intestinal microsomes of rats and humans2014
- Author(s)
  Fujino C., Watanabe Y., Uramaru N., Kitamura S
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 64 Pages: 361-368
- DOI
  10.1016/j.fct.2013.12.013
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates.2014
- Author(s)
  Sanoh S, Santoh M, Takagi M, Kanayama T, Sugihara K, Kotake Y, Ejiri Y, Horie T, Kitamura S, Ohta S
- Journal Title
  
  Toxicology in Vitro
  
  Volume: (in press) Pages: 192-197
- DOI
  10.1016/j.tiv.2014.05.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-25340049
[Journal Article] Structure-activity relationship of a series of 17 parabens and related compounds for histamine release in rat peritoneal mast cells and skin allergic reaction in guinea pigs2014
- Author(s)
  Uramaru N., Inoue T., Watanabe Y., Shigematsu H., Ohta S., Kitamura S.
- Journal Title
  
  The Journal of Toxicological Sciences, 39(1) 83-90 (201
  
  Volume: 39 Pages: 83-90
- NAID
  130004447118
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25340049
[Journal Article] 2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes.2014
- Author(s)
  Kamikyouden N., Sugihara K., Watanabe Y., Uramaru N., Murahashi T., Kuroyanagi M., Sanoh S., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica.
  
  Volume: 43(6) Pages: 514-519
- DOI
  10.3109/00498254.2012.742217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053, KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] In vitro metabolism of cis- and trans-permethrin by rat liver microsomes, and its effect on estrogenic and anti-androgenic activities.2014
- Author(s)
  Tange, S., Fujimoto, N., Uramaru, N., Sugihara, K., Ohta, S., Kitamura, S
- Journal Title
  
  Environ Toxicol Pharmacol.
  
  Volume: 37 Pages: 996-1005
- DOI
  10.1016/j.etap.2014.03.009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U205) cell-based reporter gene assays2013
- Author(s)
  Suzuki, G.
- Journal Title
  
  Environ Sci Technol.
  
  Volume: 47 Pages: 2898-2908
- DOI
  10.1021/es304691a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221003, KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23681011, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25281050, KAKENHI-PROJECT-25340049
[Journal Article] Cell type-dependent agonist/antagonist activities of polybrominated diphenyl ethers.2013
- Author(s)
  Nakamura N, Matsubara K, Sanoh S, Ohta S, Uramaru N, Kitamura S, Yamaguchi M, Sugihara K, Fujimoto N
- Journal Title
  
  Toxicology Letters
  
  Volume: 223(2) Pages: 192-197
- DOI
  10.1016/j.toxlet.2013.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor a and b and androgen receptor2013
- Author(s)
  Watanabe Y., Kojima H., Takeuchi S., Uramaru N., Ohta S, Kitamura S
- Journal Title
  
  Food Chem Toxicol.
  
  Volume: 57 Pages: 227-234
- DOI
  10.1016/j.fct.2013.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Strain Difference of Oxidative Metabolism of the Sedative-hypnotic Zaleplon by Aldehyde Oxidase and Cytochrome P450 In Vivo and In Vitro in Rats2013
- Author(s)
 Tanoue C., Sugihara K., Uramaru N., Watanabe Y., Tayama Y., Ohta S., Kitamura S
- Journal Title
 
 Drug Metabolism and Pharmacokinetics
 
 Volume: 28(3) Issue: 3 Pages: 269-273
- DOI
 10.2133/dmpk.dmpk-12-nt-103
 10.2133/dmpk.DMPK-12-NT-103
- NAID
 130004463299
- ISSN
 1347-4367, 1880-0920
- Language
 English
- Data Source
 KAKENHI-PROJECT-22510071
[Journal Article] Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation2013
- Author(s)
  Kawabata K., Sugihara K., Sanoh S., Kitamura S., Ohta S
- Journal Title
  
  J. Toxicol. Sci.
  
  Volume: 38(2) Issue: 2 Pages: 215-223
- DOI
  10.2131/jts.38.215
- NAID
  10031151425
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126
[Journal Article] Comparative study of the hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by microsomes of various rat and human tissues2013
- Author(s)
  Ozaki H., Sugihara K., WatanabeY., Fujino C., Uramaru N., Sone T., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica
  
  Volume: (in press) Pages: 1064-1072
- DOI
  10.3109/00498254.2013.802059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepaticytes2013
- Author(s)
  Tanoue C., Sugihara K., Uramaru N., Tayama Y., Watanabe Y., Horie T., Ohta S., Kitamura S
- Journal Title
  
  Xenobiotica
  
  Volume: (in press) Pages: 956-962
- DOI
  10.3109/00498254.2013.788232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Ultraviolet-photoproduct of acetaminophen: Structure determination and evaluation of ecotoxicological effect.2012
- Author(s)
  Kawabata K., Sugihara K., Sanoh S., Kitamura S.,Ohta S
- Journal Title
  
  J Photochem Photobiol A Chem
  
  Volume: 249 Pages: 29-35
- DOI
  10.1016/j.jphotochem.2012.07.018
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara K, Sanoh S, Ohta S, Kitamura S, Sugihara K, Fujimoto N
- Journal Title
  
  Toxicol Lett
  
  Volume: 208 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara, Kana ; Sanoh, Seigo ; Ohta, Shigeru ; Kitamura, Shigeyuki ; Sugihara, Kazumi ; Fujimoto, Nariaki
- Journal Title
  
  Toxicology Letters
  
  Volume: 208(1) Pages: 30-35
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effects of Polybrominated Diphenyl Ethers(PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012
- Author(s)
  Hashimoto, Shako ; Yoshimura, Hiromi ; Okada, Kazushi ; Uramaru, Naoto ; Sugihara, Kazumi ; Kitamura, Shigeyuki ; Imaoka, Susumu
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: 25(3) Pages: 656-663
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara K., Sanoh S., Ohta S., Kitamura S., Fujimoto N
- Journal Title
  
  Toxicol. Lett
  
  Volume: 208 Pages: 30-35
- DOI
  10.1016/j.toxlet.2011.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076
[Journal Article] Effects of Polybrominated Diphenyl Ethers (PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012
- Author(s)
  Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S
- Journal Title
  
  Chem Res Toxicol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Developmental Changes of Aldehyde Oxidase Activity and Protein Expression in Human Liver Cytosol2012
- Author(s)
  Tayama Y., Sugihara K., Sanoh S., Miyake K., Kitamura S., Ohta S.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 27 Issue: 5 Pages: 543-547
- DOI
  10.2133/dmpk.dmpk-11-nt-124
  10.2133/dmpk.DMPK-11-NT-124
- NAID
  130004463273
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23790212
[Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012
- Author(s)
  Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism & Disposition
  
  Volume: 40(2) Pages: 322-328
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide.2012
- Author(s)
  Matsubara K, Sanoh S, Ohta S, Kitamura S, Sugihara K, Fujimoto N.
- Journal Title
  
  Toxicol Lett.
  
  Volume: 208 Pages: 30-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510076
[Journal Article] Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats2012
- Author(s)
  Yao, H. T., Chang, Y. W., Uramaru, N., Watanabe, Y.,. Kitamura, S.,Kuo, Y. H., Lii, C.K., Yeh, T.K
- Journal Title
  
  J. Ethnopharmacol
  
  Volume: 142(1) Pages: 121-128
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] Prediction of In Vivo Hepatic Clearance and Half-life of Drug Candidates in Human using Chimeric Mice with Humanized Liver.2012
- Author(s)
  Sanoh S., Horiguchi A., Sugihara K., Kotake Y., Tayama Y., Uramaru N., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S
- Journal Title
  
  Drug Metabolism and Disposition
  
  Volume: 40(2) Pages: 2267-2272
- DOI
  10.1124/dmd.111.040923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-22790109, KAKENHI-PROJECT-23310047, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053
[Journal Article] Effects of polybrominated diphenyl ethers (PBDEs) and their derivatives on protein disulfide isomerase activity and growth hormone release of GH3 cells2012
- Author(s)
  Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S, and Imaoka S.
- Journal Title
  
  Chem. Res. Toxicol
  
  Volume: 25(3) Pages: 656-63
- DOI
  10.1021/tx200374s
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310045, KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23655162
[Journal Article] Animproved thyroid hormone reporter assay to determine the thyroid hormone-likeactivity of amiodaronebithionol, closantel and rafoxanide2012
- Author(s)
  Matsubara K., Sanoh S., Ohta S., Kitamura S., Sugihara K., Fujimoto N.
- Journal Title
  
  Toxicol. Lett
  
  Volume: 208 Pages: 30-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 26 Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama Yoshitaka ; Sugihara Kazumi ; Sanoh Seigo ; Miyake Katsushi ; Morita Shushi ; Kitamura Shigeyuki ; Ohta Shy
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 26(1)
  
  Pages: 94-101
- NAID
  130004463166
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Androgen dependent transcription of a mouse prostatic protein gene, PSP94 : involvement of estrogen receptors2011
- Author(s)
  Fujimoto N., Kitamura S., Kanno J
- Journal Title
  
  J. Steroid Biochem. Mol. Biol
  
  Volume: 127(3-5) Pages: 301-306
- DOI
  10.1016/j.jsbmb.2011.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23510076
[Journal Article] Effect of Tea Beverages on Aldehyde Oxidase Activity2011
- Author(s)
  Tayama Y., Sugihara K., Sanoh S., Miyake K., Morita S., Kitamura S., Ohta S
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26(1) Issue: 1 Pages: 94-101
- DOI
  10.2133/dmpk.dmpk-10-nt-078
  10.2133/dmpk.DMPK-10-NT-078
- NAID
  130004463166
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] Effect of tea beverages on aldehyde oxidase activity2011
- Author(s)
  Tayama, Yoshitaka ; Sugihara, Kazumi ; Sanoh, Seigo ; Miyake, Katsushi ; Marita, Shushi ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Androgen dependent transcription of a mouse prostatic protein gene, PSP94: involvement of estrogen receptors.2011
- Author(s)
  Fujimoto N, Kitamura S, Kanno J.
- Journal Title
  
  J Steroid Biochem Mol Biol.
  
  Volume: 127 Pages: 301-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510076
[Journal Article] Androgen dependent transcription of amouse prostatic protein gene, PSP94 : involvement of estrogen receptors2011
- Author(s)
  Fujimoto N., Kitamura S., Kanno J.
- Journal Title
  
  JSteroid Biochem. Mol. Biol
  
  Volume: 127 Pages: 301-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Characterization of estrogen and androgen receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2011
- Author(s)
  Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K and Kojima H.
- Journal Title
  
  Toxicology
  
  Volume: 280 Pages: 112-121
- DOI
  10.1016/j.tox.2011.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675, KAKENHI-PROJECT-22510071
[Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010
- Author(s)
  Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 26(1) Pages: 94-101
- NAID
  130004463166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics2010
- Author(s)
  Uramaru N., Shigematsu H., Toda A., Eyanagi R., Kitamura S., Ohta S.
- Journal Title
  
  J Med Chem
  
  Volume: 53 Pages: 8727-8733
- DOI
  10.1021/jm101208x
- Data Source
  KAKENHI-PROJECT-22510071
[Journal Article] Prediction of human disposition toward S3Hwarfarin using chimeric mice with humanized liver2009
- Author(s)
  Inoue, Tae ; Sugihara, Kazumi ; Ohshita, Hiroki ; Horie, Torn ; Kitamura, Shigeyuki ; Ohta, Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 24(2) Pages: 153-160
- NAID
  10025723190
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Identification of rat prostatic secreted proteins using mass spectrometric analysis and androgen-dependent mRNA expression2009
- Author(s)
  Fujimoto N, Suzuki T, Ohta S, Kitamura S.
- Journal Title
  
  J Androl. 30
  
  Pages: 669-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science
  
  Volume: 55(2) Pages: 147-160
- NAID
  110007161008
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 17(8)
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver2009
- Author(s)
  Inoue Tae ; Sugihara Kazumi ; Ohshita Hiroki ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 24(2)
  
  Pages: 153-160
- NAID
  10025723190
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi Keiko ; Furuno Nobuaki ; Kitamura Shigeyuki ; Ohta Shigeru ; Sugihara Kazumi ; Utsumi Kozo ; Hanada Hideki ; Taniguchi Kikuyo ; Suzuki Ken-ichi ; Kashiwagi Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 17(8)
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima Hiroyuki ; Takeuchi Shinji ; Uramaru Naoto ; Sugihara Kazumi ; Yoshida Takahiko ; Kitamura Shigeyuki
- Journal Title
  
  Environmental Health Perspectives 117(8)
  
  Pages: 1210-1218
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Disruption of thyroid hormone function by environmental Pollutants2009
- Author(s)
  Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Identification of ratprostatic secreted proteins using masss pectrometric analysis andandrogen-dependent mRNA expression2009
- Author(s)
  Fujimoto, N., Suzuki, T., Ohta, S., Kitamura, S.
- Journal Title
  
  J. Androl.
  
  Volume: 30 Pages: 669-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Disruption of thyroid hormone function by environmental pollutants2009
- Author(s)
  Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
- Journal Title
  
  Journal of Health Science 55(2)
  
  Pages: 147-160
- NAID
  110007161008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima, Hiroyuki ; Takeuchi, Shinji ; Uramaru, Naoto ; Sugihara, Kazumi ; Yoshida, Takahiko ; Kitamura, Shigeyuki
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 117(8) Pages: 1210-1218
- Data Source
  KAKENHI-PROJECT-21406005
[Journal Article] Metabolicactivation of proestrogens in theenvironment by cytochrome P450 system2008
- Author(s)
  Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Science
  
  Volume: 54 Pages: 343-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Affinity for ThyroidHormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers.2008
- Author(s)
  Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Science
  
  Volume: 54 Pages: 607-614
- NAID
  110006935591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008
- Author(s)
  Kitamura Shigeyuki ; Sugihara Kazumi ; Sanoh Seigo ; Fujimoto Nariaki ; Ohta Shigeru
- Journal Title
  
  Journal of Health Science 54(4)
  
  Pages: 343-355
- NAID
  110006835680
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Affinity for thyroid hormone and estrogen receptors of hydroxylated poly brominated diphenyl ethers.2008
- Author(s)
  Kitamura, Shigeyuki, et al.
- Journal Title
  
  Journal of Health Science 54(5)
  
  Pages: 607-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition2008
- Author(s)
  Kashiwagi Akihiko ; Utsumi Kozo ; Kashiwagi Keiko ; Ohta Shigeru ; Sugihara Kazumi ; Hanada Hideki ; Kitamura Shigeyuki
- Journal Title
  
  Journal of Health Science 54(3)
  
  Pages: 273-280
- NAID
  110006684374
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers2008
- Author(s)
  Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Sci. 54
  
  Pages: 607-614
- NAID
  110006935591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Affinity for thyroid hormone and estrogen receptors of hydroxylated polybrominated diphenyl ethers2008
- Author(s)
  Kitamura Shigeyuki ; Shinohara Seiji ; Iwase Eri ; Sugihara Kazumi ; Uramaru Naoto ; Shigematsu Hidenari ; Fujimoto Nariaki ; Ohta Shigeru
- Journal Title
  
  Journal of Health Science 54(5)
  
  Pages: 607-614
- NAID
  110006935591
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2008
- Author(s)
  Sugihara Kazumi ; Okayama Takashige ; Kitamura Shigeyuki ; Yamashita Keisuke ; Yasuda Mineo ; Miyairi Shinichi ; Minobe Yasushi ; Ohta Shigeru
- Journal Title
  
  Archives of Toxicology 82(1)
  
  Pages: 5-11
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008
- Author(s)
  Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
- Journal Title
  
  J. Health Sci. 54
  
  Pages: 343-355
- NAID
  110006835680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20510065
[Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver2008
- Author(s)
  Kitamura Shigeyuki ; Nitta Kayoko ; Tayama Yoshitaka ; Tanoue Chiaki ; Sugihara Kazumi ; Inoue Tae ; Horie Toru ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Disposition 36(7)
  
  Pages: 1202-1205
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system.2008
- Author(s)
  Kitamura, Shigeyuki, et al.
- Journal Title
  
  Journal of Health Science 54(4)
  
  Pages: 343-355
- NAID
  110006835680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.2008
- Author(s)
  Kitamura, Shigeyuki, et al.
- Journal Title
  
  Drug Metabolism and Disposition 36(7)
  
  Pages: 1202-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver2008
- Author(s)
  Inoue Tae ; Nitta Kayoko ; Sugihara Kazumi ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
- Journal Title
  
  Drug Metabolism and Disposition 36(12)
  
  Pages: 2429-2433
- Data Source
  KAKENHI-PROJECT-20590122
[Journal Article] Quantitative determination of lobe specificity of mrna expression of androgen-dependent genes in the rat prostate gland.2007
- Author(s)
  Suzuki., T., Fujimoto., N., Kitamura, S., Ohta, S.
- Journal Title
  
  Endocr. J. 54
  
  Pages: 123-132
- NAID
  10019479578
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] In vivo function of the 5'fianking region of mouse estrogen receptor beta gene. Yoshito Tezuka, Kyoko Takahashi, Tomoharu Suzuki, Shigeyuki Kitamura2007
- Author(s)
  N., Fujimoto, O., Nakajima, S., Kitamura, S., Ohta
- Journal Title
  
  J Steroid Biochem Mol Biol 105
  
  Pages: 57-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolyzed oroducts in rats2007
- Author(s)
  Y., Nakamura, K., Sugihara, T., Sone, M., Isobe, S., Ohta, S., Kitamura
- Journal Title
  
  Toxicology 235
  
  Pages: 176-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Quantitative determination of lobe specificity of mRNA expression of androgen -dependent genes in the rat prostate gland2007
- Author(s)
  T., Suzuki, N., Fujimoto, S., Kitamura, S., Ohta
- Journal Title
  
  Endocrine Journal 54(1)
  
  Pages: 123-132
- NAID
  10019479578
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Quantitative determination of lobe specificity of mrna expression of and rogen-dependent genes in the rat prostate gland2007
- Author(s)
  Suzuki., T., Fujimoto., N., Kitamura, S., Ohta, S.
- Journal Title
  
  Endocr.J. 54
  
  Pages: 123-132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Effects of environmental antiandrogenic chemicals on expression of androgen -responsive genes in rat prostate lobes2007
- Author(s)
  T., Suzuki, N., Fujimoto, S., Kitamura, S., Ohta
- Journal Title
  
  Journal of Health Science 53(4)
  
  Pages: 401-405
- NAID
  110006366919
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007
- Author(s)
  K., Sugihara, T., Okayama, S., Kitamura, K., Yamashita, M., Yasuda, S., Miyairi, Y., Minobe, S., Ohta
- Journal Title
  
  Archives of Toxicology 82
  
  Pages: 5-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Invivo function of the 5'flanking region of mouse estrogen receptor beta gene2007
- Author(s)
  Fujimoto, N., Nakajima, O., Suzuki, T., Kitamura, S., Ohta, S.
- Journal Title
  
  J.Steroid Biochem.Mol.Biol. 105
  
  Pages: 57-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Academic Press2006
- Author(s)
  Kitamura, Shigeyuki, et al.
- Journal Title
  
  Toxicology of Organophosphate and Carbamate Compounds
  
  Pages: 481-494
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Drug-metabolizing ability of molybdenum hydroxylases.2006
- Author(s)
  Kitamura, Shigeyuki, etal.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 21(2)
  
  Pages: 83-98
- NAID
  10017422927
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Identification of prostatic-secreted proteins in mice by mass spectrometric analysis and evaluation of lobe-specific and androgen-dependent mRNA expression.2006
- Author(s)
  Fujimoto, N., Akimoto, Y., Suzuki, T., Kitamura, S., Ohta, S.
- Journal Title
  
  J. Endo. 190
  
  Pages: 793-803
- NAID
  120000878100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Identification of prostatic-secreted proteins in mice by mass spectrometric analysis and evaluation of lobe-specific and androgen-dependent mRNA expression2006
- Author(s)
  Fujimoto, N., Akimoto, Y., Suzuki, T., Kitamura, S., Ohta, S.
- Journal Title
  
  J.Endo. 190
  
  Pages: 793-803
- NAID
  120000878100
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] In vivo function of the 5'flanking region of mouse estrogen receptor beta gene.2006
- Author(s)
  Fujimoto, N., Nakajima, 0., Suzuki, T., Kitamura, S., Ohta, S.
- Journal Title
  
  J. Steroid Biochem. Mol. Biol. 105
  
  Pages: 57-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Drug-metabolizing ability of molybdenum hydroxylases.2006
- Author(s)
  Kitamura, Shigeyuki, et al.
- Journal Title
  
  Drug Metabolism and Pharmacokinetics 21(2)
  
  Pages: 83-98
- NAID
  10017422927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Suppression of amphibian metamorphosis by bisphenol A and related chemical substances2006
- Author(s)
  Y., Goto, S., Kitamura, K., Kashiwagi, K., Oofusa, O., Tooi, K., Yoshizato, J., Sato, S., Ohta, A., Kashiwagi
- Journal Title
  
  Journal of Health Sciences 52(2)
  
  Pages: 160-168
- NAID
  110006163232
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Effects of stilbene and related compounds on reproductive organs in B6C3F1/Crj mouse H. Fujita, Y. Okimura, T. Utsumi, S. Kitamura, H. Kuroki, T. Otsuki, J. Sasaki, A. Kashiwag2006
- Author(s)
  S., Sanoh, S., Kitamura, R., Kohta, K., Sugihara, S., Ohta, H., Watanabe
- Journal Title
  
  Journal of Health Sciences 52(5)
  
  Pages: 613-622
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Journal Article] Cloning and characterization of the 5'-flanking region of the rat estrogen receptor β gene2005
- Author(s)
  Fujimoto, N., Asano, K., Usui, T., Honda, H., Kitamura, S.
- Journal Title
  
  J. Steroid Biochem. Mol. Biol. 94
  
  Pages: 15-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Toxicology 208巻
  
  Pages: 377-387
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds : Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Life Sciences 76巻
  
  Pages: 1589-1601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005
- Author(s)
  S.Kitamura, N.Jinno, T.Suzuki, K.Sugihara, S.Ohtaら
- Journal Title
  
  Toxicology 208
  
  Pages: 377-387
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005
- Author(s)
  S.Kitamura, T.Suzuki, S.Sanoh, R.Kohta, N.Jinno, K.Sugiharaら
- Journal Title
  
  Toxicological Sciences 84
  
  Pages: 249-259
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Toxicological Sciences 84巻
  
  Pages: 249-259
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture.2005
- Author(s)
  Kitamura, S., Jinno, N., Suzuki, T., Sugihara, K., Ohta, S., Kuroki, H., Fujimoto, N.
- Journal Title
  
  Toxicology 208
  
  Pages: 377-387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreen2005
- Author(s)
  T.Suzuki, S.Kitamura, R.Khota, K.Sugihara, N.Fujimoto, S.Ohta
- Journal Title
  
  Toxicology and Applied Pharmacology 203
  
  Pages: 9-17
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Metabolism of the alpha,beta-unsaturated ketones,chalcone and trans-4-phenyl-3-buten-2-one,by rat liver microsomes and estrogenic activity of the metabolites2005
- Author(s)
  Kohno Y., Kitamura S., Sanoh S., Sugihara K., Fujimoto N., Ohta S.
- Journal Title
  
  Drug Metab.Dispos. 33
  
  Pages: 1115-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Toxicological Sciences 84
  
  Pages: 249-259
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds : affmity to the mammalian thyroid hormone receptor, and effect on tadpole.2005
- Author(s)
  Kitamura, S., Kato, T., lida, M., Jinno, N., Suzuki, T, Ohta, S., Fujimoto, N., Hanada, H., Kashiwagi, K., Kashiwagi, A.
- Journal Title
  
  Life Sci. 76
  
  Pages: 1589-1601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture.2005
- Author(s)
  Kitamura, S.et al.
- Journal Title
  
  Toxicology 208(3)
  
  Pages: 377-387
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Cloning and characterization of the 5'-flanking region of the rat estrogen receptor βgene2005
- Author(s)
  Fujimoto, N., Asano, K., Usui, T., Honda, H., Kitamura, S.
- Journal Title
  
  J.Steroid Biochem.Mol.Biol. 94
  
  Pages: 15-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds : affinity to the mammalian thyroid hormone2005
- Author(s)
  S.Kitamura, T.Kato, M.Iida, N.Jinno, T.Suzuki, S.Ohtaら
- Journal Title
  
  Life Sciences 76
  
  Pages: 1589-1601
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Toxicology 208
  
  Pages: 377-387
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005
- Author(s)
  Kitamura, S., Jinno, N., Suzuki, T., Sugihara, K., Ohta, S., Kuroki, H., Fujimoto, N.
- Journal Title
  
  Toxicology 208
  
  Pages: 377-387
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Anti-thyroidhormonal activity of tetrabromobisphenol A,aflame retardant,and related compounds:affinity to the mammalian thyroid hormone receptor,and effect on tadpole2005
- Author(s)
  Kitamura, S., Kato, T., Iida, M., Jinno, N., Suzuki, T, Ohta, S., Fujimoto, N., Hanada, H., Kashiwagi, K., Kashiwagi, A.
- Journal Title
  
  Life Sci. 76
  
  Pages: 1589-1601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005
- Author(s)
  Kitamura, S., Suzuki, T., Sauoh, S., Kohta, R., Jinno, N., Sugihara, K., Yoshihara, S., Fujimoto, N., Watanabe, H., Ohta, S.
- Journal Title
  
  Toxicol.Sci 84
  
  Pages: 1-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds. Toxicol. Sci., 84, 1-12(2005)2005
- Author(s)
  Kitamura, S., Suzuki, T., Sanoh, S., Kohta, R., Jinno, N., Sugihara, K., Yoshihara, S., Fujimoto, N., Watanabe, H., Ohta, S.
- Journal Title
  
  Toxicol. Sci. 84
  
  Pages: 1-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Metabolism of the alpha, beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites.2005
- Author(s)
  Kohno Y., Kitamura S., Sanoh S., Sugihara K., Fujimoto N., Ohta S.
- Journal Title
  
  Drug Metab. Dispos. 33
  
  Pages: 1115-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Comparative Study of the Endocrine-Disrupting Activity of Bisphenol A and 19 Related Compounds.2005
- Author(s)
  Kitamura, S.et al.
- Journal Title
  
  Toxicological Sciences 84(2)
  
  Pages: 249-259
- Data Source
  KAKENHI-PROJECT-17590102
[Journal Article] Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens.2005
- Author(s)
  Suzuki, T., Kitamura, S., Khota, R., Sugihara, K., Fujimoto, N., Ohta, S.
- Journal Title
  
  Toxicol. Appi. Pharmacol. 203
  
  Pages: 9-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds : Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis2005
- Author(s)
  Kitamura et al.
- Journal Title
  
  Life Sciences 76
  
  Pages: 1589-1601
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens2005
- Author(s)
  Suzuki, T., Kitamura, S., Khota, R., Sugihara, K., Fujimoto, N., Ohta, S.
- Journal Title
  
  Toxicol.Appl.Pharmacol. 203
  
  Pages: 9-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510046
[Journal Article] Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo2004
- Author(s)
  K.Sugihara, S.Kitamura, T.Yamada, T.Okayama, S.Ohta
- Journal Title
  
  Biochemical and Biophysical Research Communication 318
  
  Pages: 571-578
- Data Source
  KAKENHI-PROJECT-16590092
[Journal Article] Inhibitory effect of organotin compounds on rat neuronal nitric oxide synthase through, interaction with calmodulin2004
- Author(s)
  K.Ohashi, S.Kominami, T.Yamazaki, S.Ohta, S.Kitamura
- Journal Title
  
  Biochemical and Biophysical Research Communications 324(1)
  
  Pages: 178-185
- Data Source
  KAKENHI-PROJECT-16590092
[Presentation] ラズベリーケトンの還元的代謝および3T3-L1 細胞の脂肪化抑制2019
- Author(s)
  浦丸直人，坂本佳澄，鈴木智貴，木根淵有香，川村涼，渡部容子，北村繁幸，樋口敏幸
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 離乳期におけるラット肝CYPおよびaldehyde oxidaseの変動2019
- Author(s)
  杉原数美, 村川晃大, 荒井美幸, 田山剛崇, 清水良, 北村繁幸, 太田茂
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Aldehyde oxidase およびCYP2A6 がnicotine 代謝に及ぼす影響2019
- Author(s)
  田山剛崇, 西村さとみ, 杉原数美, 北村繁幸, 佐和章弘, 三宅勝志
- Organizer
  日本薬学会139年会　千葉幕張メッセ　2019年3月20-22日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Assessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018
- Author(s)
  Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini, Shigeru Ohta, Yaichiro Kotake
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] Sex differences of aldehyde oxidases in mouse liverAssessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018
- Author(s)
  Kazumi Sugihara, Yoshitaka Tayama, Seigo Sanoh, Shigeyuki Kitamura, Shigeru Ohta
- Organizer
  2018 International Meeting on 22nd MDO and 33rd JSSX
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] リン系難燃剤のラット肝および小腸カルボキシルエステラーゼに対する阻害効果2018
- Author(s)
  津越幸枝，渡部容子，杉原数美，北村繁幸
- Organizer
  フォーラム2018衛生薬学・環境トキシコロギー　アルカス佐世保　2018年9月10-11日
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] ベンズトリアゾール系紫外線吸収剤のPXR, CAR,およびPPARα活性とシトクロムP450活性への影響2017
- Author(s)
  服部祥子，渡部容子，立花　研，小島弘幸，吉成浩一，北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 臭素化難燃剤PBDE類によるAhRの活性化を介したUGT遺伝子発現誘導機構．内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング2017
- Author(s)
  清水　良，浦丸直人，渡部容子, 太田　茂, 北村繁幸, 杉原数美
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 塩素消毒処理による医薬品および生活関連化学物質の毒性変動調査2017
- Author(s)
  國澤和憲、岡田達司、堂脇美緒、井上沙也香、清水　良、北村繁幸、太田　茂、杉原数美
- Organizer
  フォーラム2017：衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 合成ムスク類のラットin vivoにおける肝シトクロムP450活性への影響2017
- Author(s)
  渡部容子，服部祥子，立花　研，佐能正剛，太田　茂，北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] フタル酸エステル類とその代謝物が核内受容体およびの転写活性に及ぼす影響2017
- Author(s)
  佐藤志穂、渡部容子、立花　研、浦丸直人、小島弘幸、吉成浩一、樋口敏幸、北村繁幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] マウス肝アルデヒド酸化酵素分子種の系統差と性差2017
- Author(s)
  杉原数美, 平本耕一, 田坂真希, 田山剛崇, 佐能正剛, 太田　茂, 北村繁幸
- Organizer
  日本薬物動態学会第32回年会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] カルバメート系農薬のラットおよびヒトでのin vitro代謝とその核内受容体活性への影響2017
- Author(s)
  藤野智恵里，渡部容子，浦丸直人，佐能正剛，小島弘幸，吉成浩一，太田　茂，北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] マウス肝アルデヒドオキシダーゼの性特異的発現機序の検討2017
- Author(s)
  内藤祐子，田坂真希，富吉博也，濱﨑千尋，清水　良，佐能正剛，太田　茂，北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] 薬物代謝酵素アルデヒドオキシダーゼのマウスにおける性差と系統差2017
- Author(s)
  岸沙也香、村川晃大、平本耕一、清水　良、佐能正剛、太田　茂、北村繁幸、杉原数美
- Organizer
  第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] リン系難燃剤のラットカルボキシルエステラーゼ活性に対する阻害効果2017
- Author(s)
  津越幸枝，渡部容子，杉原数美，北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] リン系難燃剤のラット核内受容体PXR、CARおよびPPARαに対するアゴニスト活性2017
- Author(s)
  柳川ひらり，渡部容子，小島弘幸，吉成浩一,　北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K00559
[Presentation] ラット肝、小腸及び膵臓ミクロソームのフタル酸エステルに対する加水分解活性の基質特異性2016
- Author(s)
  森口恭子，渡部容子，杉原数美，北村繁幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] パラベン、サリチル酸エステル及びフタル酸エステルの核内受容体の構造活性相関2016
- Author(s)
  津越幸枝，谷川悠華，渡部容子，浦丸直人，小島弘幸，北村繁幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Allopurinol代謝に及ぼす投与量の影響2016
- Author(s)
  田山剛崇，杉原数美，三宅勝志，北村繁幸，太田　茂
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 臭素化難燃剤のPBDEおよびその代謝物による肝UGT遺伝子発現への影響2016
- Author(s)
  清水　良，浦丸直人，渡部容子，太田　茂，北村繁幸，杉原数美
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] サリチル酸及びサリチル酸エステル類の核内受容体ER, AR, PXR及びCARに対する活性2015
- Author(s)
  谷川悠華，小山賢一，渡部容子，浦丸直人，小島弘幸，藤本成明，北村繁幸
- Organizer
  フォーラム2015 衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] リン系難燃剤のラット肝カルボキシルエステラーゼ活性に対する阻害効果2015
- Author(s)
  渡部容子，井上智賀，谷川悠華，浦丸直人，杉原数美，小島弘幸，北村繁幸
- Organizer
  フォーラム2015 衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] In vitro およびin vivo における環境化学物質の甲状腺ホルモンかく乱影響評価2014
- Author(s)
  中村直樹, 佐能正剛, 松原加奈, 杉原数美, 浦丸直人, 北村繁幸, 藤本成明, 太田茂
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] In vitroおよびin vivoにおける環境化学物質の甲状腺ホルモンかく乱影響評価2014
- Author(s)
  中村直樹,松原加奈,佐能正剛浦丸直人,北村繁幸,藤本成明,,太田茂
- Organizer
  日本薬学会第134年会
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] Allopurinol代謝におけるaldehyde oxidase活性の寄与に関する検討2014
- Author(s)
  田山剛崇,杉原数美,三宅勝志,北村繁幸,太田　茂
- Organizer
  日本薬学会　第１３４年回
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460235
[Presentation] パラベン類のラット肥満細胞におけるヒスタミン遊離作用及びモルモット皮膚反応の構造活性相関の検討2013
- Author(s)
  浦丸直人, 井上俊夫, 渡部容子, 太田茂, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 保存剤パラベン類のヒトおよびラット組織ミクロソームでの加水分解活性の構造代謝相関2013
- Author(s)
  渡部容子, 田中聡一, 藤野智恵里, 浦丸直人, 太田茂, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ラット肝ミクロソームによるベンゾフェノン系紫外線吸収剤の代謝とエストロゲン活性の変動2013
- Author(s)
  白鳥由衣, 渡部容子, 小島弘幸, 武内伸治, 江森千紘, 浦丸直人, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Allopurinol 代謝におけるxanthine oxidase および aldehyde oxidaseの関与2013
- Author(s)
  田山武崇, 杉原数美, 三宅勝志, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 新生仔ラットの甲状腺ホルモン応答遺伝子発現への臭素化難燃剤の影響2013
- Author(s)
  藤本成明, 松原加奈, 佐能正剛,太田茂,浦丸直人,北村繁幸, 宮川信一, 井口泰泉
- Organizer
  環境ホルモン学会第16回研究発表会
- Place of Presentation
  東京
- Year and Date
  2013-12-12
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] Profiling of thyroid hormone related gene expression to access the neonatal effects of endocrine disruptors2013
- Author(s)
  藤本成明, 中村直樹,松原加奈,佐能正剛,太田茂,北村繁幸
- Organizer
  1st international symposium on profiling
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ヒト・マウスにおけるアルデヒドオキシダーゼの代謝活性と基質特異性の比較2013
- Author(s)
  小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山武崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] アセトアミノフェンおよびスリンダクの水環境中における光分解物の同定2013
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 保存剤パラベン類のラット肝および小腸ミクロソームでのエステル交換反応2013
- Author(s)
  藤野智恵里, 渡部容子, 浦丸直人, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 調剤薬局調剤室における医薬品による室内環境汚染2013
- Author(s)
  村橋毅, 伊藤貴信, 大津亜紀子, 小宮山拓実, 橋沼亨, 樋口敏幸, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Profiling of thyroid hormone related gene expression to access the neonatal effects of endocrine disruptors2013
- Author(s)
  Fujimoto, N., Matsubara, K., Sanoh, S., Ohta, S., Kitamura, S
- Organizer
  1st international symposium on profiling
- Place of Presentation
  リスボン(ポルトガル)
- Year and Date
  2013-09-03
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 穀物によるマウス肝薬物代謝酵素の変動2013
- Author(s)
  清水良, 山口雅史, 浦丸直人, 黒木広明, 北村繁幸, 太田茂, 杉原数美
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 紫外線吸収剤ベンゾフェノン-3 のラットおよびヒトによる代謝とエストロゲンおよび抗アンドロゲン活性の変動2013
- Author(s)
  渡部容子, 小島弘幸, 武内伸治, 長本哲明, 浦丸直人, 太田茂, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] PCB および PBDE の水酸化代謝物のヨードチロシン脱ヨウ素化酵素阻害作用2013
- Author(s)
  山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 新生仔ラットの甲状腺ホルモン応答遺伝子発現への臭素化難燃剤の影響2013
- Author(s)
  藤本成明, 中村直樹,松原加奈,佐能正剛,太田茂,浦丸直人,北村繁幸,宮川信一,井口泰泉
- Organizer
  環境ホルモン学会第16回研究発表会
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 臭素化難燃剤の甲状腺ホルモン活性-細胞依存的アゴニスト・アンタゴニスト作用2013
- Author(s)
  藤本成明, 中村直樹, 松原加奈, 佐能正剛,太田茂,杉原数美, 北村繁幸
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 臭素化難燃剤の甲状腺ホルモン活性－細胞依存的アゴニスト・アンタゴニスト作用2013
- Author(s)
  藤本成明, 中村直樹,松原加奈,佐能正剛,太田茂,杉原数美,北村繁幸
- Organizer
  第86回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト体内動態予測の検証2013
- Author(s)
  藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 釜山市(大韓民国)の市街地を流域とする温泉川での医薬品汚染調査2012
- Author(s)
  杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
- Organizer
  第46回日本水環境学会年会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] セリ科生薬エキスのラット肝シトクロム P450 系への影響2012
- Author(s)
  荒井優子, 青木純一, 渡部容子, 浦丸直人, 山路誠一, 北村繁幸
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境化学物質の転写活性化を介した甲状腺ホルモン撹乱作用2012
- Author(s)
  松原加奈, 佐能正剛,藤本成明, 杉原数美,北村繁幸,太田茂
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト血中動態予測性の検証2012
- Author(s)
  藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] アセトアミノフェンの水環境中における光分解と光毒性2012
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Metabolism of benzophenone-3, a sunscreen, by rat liver microsomes and its modification of the Endcrine disrupting activity,2012
- Author(s)
  Kitamura et al.
- Organizer
  SETAC Asia Pacific 2012
- Place of Presentation
  Kumamoto
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 甲状腺ホルモン様化学物質アミオダロン曝露によるカエルの変態に対する影響2012
- Author(s)
  佐能正剛, 柏木啓子, 花田秀樹, 松原加奈, 川畑公平, 中村直樹, 鈴木賢一,山本卓, 新海正, 藤本成明, 杉原数美, 北村繁幸, 柏木昭彦, 太田茂
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 62 種生薬エキスの Ah レセプター結合活性の評価2012
- Author(s)
  杉原数美, 渡部容子, 北村繁幸, 原田亜紀子, 太田茂, 山路誠一
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 環境科学物質による甲状腺ホルモン撹乱作用の in vitro および in vivo 評価2012
- Author(s)
  松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] アルコール存在下におけるパラベン類の代謝2012
- Author(s)
  藤野智恵里, 田中聡一, 渡部容子, 浦丸直人, 北村繁幸
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 水環境中医薬類の太陽光・紫外線による毒性変動2012
- Author(s)
  川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  第39回日本毒性学会学術年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Prediction of human pharmacokinetics by allometric scaling using chimeric mice with humanized liver2012
- Author(s)
  Sanoh S., Naritomi Y., Sato K., Kawamura A., Horiguchi A., Sugihara K., Tateno C., Horie T., Kitamura S., Ohta S
- Organizer
  19th International Symposium on Microsomes and Drug Oxidations 12th European Regional ISSX Meeting
- Place of Presentation
  Noordwijk aan Zee, Netherlands
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Metabolism of parabens by rat liver microsomes and its modification of the endocrine-disrupting activity.2012
- Author(s)
  Uramaru, N., Watanabe, Y.,. Kitamura, S.,Takeuchi S., Kojima H
- Organizer
  SETAC (The Society of Environmental Toxicology and Chemistry) Asia Pacific 2012 Meeting Abstract
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Effects of neonatal exposure to thyroid hormones on gene expression profile of the pituitary-thyroid-liver in rats2012
- Author(s)
  Fujimoto, N., Matsubara, K., Sanoh, S., Ohta, S., Kitamura, S., Sugihara, K
- Place of Presentation
  フェレンツェ(イタリア)
- Year and Date
  2012-05-08
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 食餌がマウス肝薬物代謝酵素に及ぼす影響の1H-NMR メタボローム解析2012
- Author(s)
  杉原数美, 佐光華佳, 田上加苗, 三間昭平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 抗菌剤パラベン類の内分泌撹乱作用の特徴と構造活性相関2012
- Author(s)
  渡部容子, 小島弘幸, 武内伸治, 浦丸直人, 太田茂, 北村繁幸
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Effect of UV irradiation on the ecotoxicity of pharmaceuticals in aquatic environment2012
- Author(s)
  Kawabata K., Ogawa Y., Sugihara K., Sanoh S., Kitamura S., Ohta S.
- Organizer
  The 6th International Congress of Asian Society of Toxicology
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] カルボキシエステラーゼおよびシトクロム P450 が関与する抗菌剤パラベン類の代謝2012
- Author(s)
  田中聡一, 渡部容子, 浦丸直人, 北村繁幸
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Metabolism of benzophenone-3, a sunscreen, by rat liver microsomes and modification of the endocrine-disrupting activity2012
- Author(s)
  Kitamura S., Watanabe Y., Uramaru N., Takeuchi S., Kojima H.
- Organizer
  SETAC (The Society of Environmental Toxicology and Chemistry) Asia Pacific 2012 Meeting Abstract
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ラット肝ミクロソームによるベンゾフェノン系紫外線吸収剤の代謝2012
- Author(s)
  白鳥由衣, 渡邊麻友, 渡部容子, 浦丸直人, 北村繁幸
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ヒト・マウス・ヒト肝キメラマウスにおけるアルデヒドオキシダーゼの酵素活性の比較2012
- Author(s)
  小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山剛崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 臭素化難燃剤の甲状腺ホルモン活性-細胞依存的アゴニスト・アンタゴニスト作用2012
- Author(s)
  藤本成明, 松原加奈, 佐能正剛,太田茂, 山口雅史, 杉原数美,浦丸直人,北村繁幸
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ラット肝細胞スフェロイドにおける蛍光プローブを用いたアセトアミノフェン、ジクロフェナクによる肝毒性評価2012
- Author(s)
  山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第27回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ラットにおける紫外線吸収剤ベンゾフェノン‐3 の in vivo‐in vitro 代謝の相関性2012
- Author(s)
  長本哲明, 山川亞以子, 中尾浩文, 渡部容子, 浦丸直人, 北村繁幸
- Organizer
  第56回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] ラット肝での新規甲状腺ホルモン応答遺伝子pdxk の同定とプロモーター解析2012
- Author(s)
  藤本成明, 松原加奈, 佐能正剛,太田茂,北村繁幸
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 環境化学物質による甲状腺ホルモン撹乱作用のin vitro およびin vivo 評価2012
- Author(s)
  松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
- Organizer
  衛生薬学・環境トキシコロジーフォーラム
- Place of Presentation
  名古屋
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 水環境中医薬品類の太陽光および紫外線による分解と毒性変動調査2012
- Author(s)
  川畑公平、尾川雄一、杉厘数圭、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011
- Author(s)
  内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
- Organizer
  フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 新生仔ラットへの甲状腺ホルモン作用物質暴露の影響2011
- Author(s)
  藤本成明, 松原加奈, 佐能正剛,太田茂,杉原数美,北村繁幸
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市(北海道大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、雌、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 新生仔ラットへの甲状腺ホルモン作用物質暴露の影響2011
- Author(s)
  藤本成明、松原加奈、佐能正剛、太田茂、杉原数美、北村繁幸
- Organizer
  環境ホルモン学会研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] ラット肝における甲状腺ホルモン応答遺伝子の同定2011
- Author(s)
  藤本成明, 松原加奈, 佐能正剛,太田茂,北村繁幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン攪乱作用in vitro評価2011
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン撹乱作用in vitro評価2011
- Author(s)
  松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(要旨発表)
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011
- Author(s)
  内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市(北海道大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
- Organizer
  第45回日本水環境学会年会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 甲状腺ホルモン様物質のアフリカツメガエルの自然変態に対する影響評価2011
- Author(s)
  佐能正剛, 柏木啓子, 花田秀樹, 松原加奈,川畑公平, 新海正, 山本卓, 鈴木賢一, 藤本成明, 杉原数美,北村繁幸, 柏木昭彦, 太田茂
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011
- Author(s)
  川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡市(グランシップ静岡など)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011
- Author(s)
  杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
- Organizer
  フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数圭, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010
- Author(s)
  松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京都
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  衛生薬学・環境トキシコロジーフォーラム2010
- Place of Presentation
  東京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入河川での医薬品による水汚染調査2010
- Author(s)
  杉原数美、尾川雄一、川畑公平、佐光華佳、佐能正剛、太田茂、西嶋渉、北村繁幸
- Organizer
  第44回日本水環境学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一,杉原数美,川畑公平,佐光華佳,佐能正剛,北村繁幸,太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質のProtein Disulfide Isomerase(PDI)への結合による内分泌系に対する影響2010
- Author(s)
  佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  衛生薬学・環境トキシコロジーフォーラム2010
- Place of Presentation
  東京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] Requirement of estrogen receptorαforandrogen dependent transcription of amouse prostatic protein gene, PSP942010
- Author(s)
  Fujimoto N., Kitamura S., Ohta, S.
- Organizer
  14thInternational Congress on HormonalSteroids and Hormones & Cancer, Edinburgh
- Place of Presentation
  Edinburgh,U. K.
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] マウスPSP94のアンドロゲン応答性転写機構-エストロゲン受容体の関与2010
- Author(s)
  藤本成明, 北村繁幸
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本トキシコロジー学会
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川での医薬品による水汚染調査2010
- Author(s)
  杉原数美, 尾川雄一, 川畑公平, 佐光華佳, 佐能正剛, 太田茂, 西嶋渉, 北村繁幸
- Organizer
  第44回日本水環境学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010
- Author(s)
  松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] マウスPSP94のアンドロゲン応答性転写機構.エストロゲン受容体の関与2010
- Author(s)
  藤本成明, 北村繁幸
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] ,広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010
- Author(s)
  杉原数美、尾川雄一、佐能正剛、北村繁幸,太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010
- Author(s)
  佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  第130回日本薬学会年会
- Place of Presentation
  岡山市
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] Requirement of Estrogen Receptor a for Androgen Dependent Transcription of a Mouse Prostatic Protein Gene, PSP942010
- Author(s)
  Fujimoto, N., Kitamura, S., Ohta, S.
- Organizer
  14th International Congress on Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  Edinburgh, U.K.
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010
- Author(s)
  尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, Yuwano, A. H. Syahrani, M.佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈,佐能正剛,岩瀬恵理,藤本成明,浦丸直人,杉原数美,加藤善久,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキわシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010
- Author(s)
  秋吉里絵,古道律子,宗重美恵子,杉原数美,尾川雄一,川畑公平,佐能正剛,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 新生仔期ラットへの甲状腺ホルモン様物質曝露による影響評価2010
- Author(s)
  松原加奈, 佐能正剛,藤本成明, 杉原数美,北村繁幸,太田茂
- Organizer
  フォーラム2011 衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010
- Author(s)
  松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美,尾川雄一,佐光華佳,M.Yuwano, A.H.Syahrani,佐能正剛,北村繁幸,太田茂
- Organizer
  フォーラム2010衛生環境トキわシコロジー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010
- Author(s)
  佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 環境化学物質のproteindisulfide isomerase(PDI)への結合による内分泌系に対する影響2010
- Author(s)
  佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー
- Place of Presentation
  東京
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査～アイルランガ大学との共同調査～2010
- Author(s)
  杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
- Organizer
  フォーラム2010衛生環境トキシコロジー
- Place of Presentation
  東京都(星薬科大学)
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップーモデル河川黒瀬川での調査一2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009
- Author(s)
  杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2009
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009
- Author(s)
  佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第12回研究発表会
- Place of Presentation
  東京都
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美,尾川雄一,佐光華佳,佐能正剛,清水良,北村繁幸,太田茂
- Organizer
  フォーラム衛生薬学・環境トキわシコロジー
- Place of Presentation
  宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009
- Author(s)
  佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
- Organizer
  環境ホルモン学会第12回研究発表会
- Place of Presentation
  東京
- Year and Date
  2009-12-07
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2009
- Author(s)
  尾川雄一, 杉厘数圭, 佐能正剛, 北村繁圭, 久保光志, 太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009
- Author(s)
  尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009
- Author(s)
  杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009
- Author(s)
  杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
- Organizer
  フォーラム衛生薬学・環境トキシコロジー
- Place of Presentation
  沖縄県宜野湾市
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 臭素化難燃剤PBDEの甲状腺ホルモン受容体結合活性の代謝による変動2009
- Author(s)
  岩瀬恵理, 小島弘幸, 杉原数美, 浦丸直人, 藤本成明, 黒木広明, 北村繁幸, 太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20510065
[Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N and Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-21406005
[Presentation] HYDROXYLATED POL YBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009
- Author(s)
  Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
- Organizer
  DIOXIN2009
- Place of Presentation
  北京市、中華人民共和国
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水流入河川水および下水処理場流入・流出水中の医薬品探索2008
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 生活排水汚染水域の医薬品探索および環境動態の検討2008
- Author(s)
  尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  フォーラム2008:衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] 医薬品による環境汚染防止に向けての廃棄方法実態調査2008
- Author(s)
  杉原数美,尾川雄一,佐能正剛,北村繁幸,久保光志,太田茂
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20590122
[Presentation] Thyroid hormonal and estrogenic activity of OH-PCB and OH-PBDE in cell culture2007
- Author(s)
  S., Kitamura, T., Suzuki, K., Sugihara, N., Uramaru, H., Kuroki, N., Fujimoto, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Metabolism of carbamate pesticides by liver microsomes and plasma of human and rat2007
- Author(s)
  S., Tange, S., Kitamura, K., Sugihara, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Parabens and phthalates : Their metabolism, AhR ligand activity, estrogenic Activity, and P450-inhibitory activity2007
- Author(s)
  H., Oz-aki, S., Shinohara, S., Tange, K., Sugihara, S., Kitamura, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Screening of AhR-binding, estrogenic and antiandrogenic activities of benzophenone derivatives used as UV stabilizers and sunscreens2007
- Author(s)
  K., sugihara, S., Shinohara, T., Suzuki, N., Fujimoto, S., Kitamura, S., Ohta
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Developmental changes of aldehyde oxidase activity in liver cytosol of young ehildren2007
- Author(s)
  Y., Tayama, K., Sugihara, S., Kitamura, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Thyroid hormonal and estrogenic activity of OH-PCB and OH-PBDE in cell culture2007
- Author(s)
  Kitamura, et. al.
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] The S-oxidation of PCB methyl ulfoxise to PCB methyl sulfone with animal liver microsomes and human cytochrome P4502007
- Author(s)
  H., Kuroki, H., Nakai, A., Toda, M., Mitsutake, R., Eyanagi, S., Kitamura
- Organizer
  DIOXIN 2007
- Place of Presentation
  Tokyo Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Chimeric mice with humanized liver as a model to predict diazepam metabolism in humans.2007
- Author(s)
  T., Inoue, K., Sugihara, S., Kitamura, H., Ohshita, T., Horie, S., Ohta
- Organizer
  8th International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] In vivo and in vitro metabolism of zaleplon in chimeric mice with humanized liver2007
- Author(s)
  C., Tanoue, K., Sugihara, S., Kitamura, T., Inoue, T., Horie, S., Ohta
- Organizer
  8th, International ISSX Meeting
- Place of Presentation
  Sendai Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590118
[Presentation] Effects of metabolism of UV-absorbers by rat liver microsomes on their nuclear receptor activation.
- Author(s)
  Watanabe Y., Kojima H., Takeuchi S., Uramaru N., Sugihara K., Sanoh S., Ohta S., Kitamura S.
- Organizer
  DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響～ラット in vivoにおける検討～
- Author(s)
  田山剛崇、杉原数美、三宅勝志、北村繁幸、太田　茂
- Organizer
  日本薬学会　第135年回
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460235
[Presentation] オス型成長ホルモン曝露がマウス肝癌細胞(Hepa 1-6)のaldehyde oxidasa発現に与える影響
- Author(s)
  藤田裕太郎，長島和也，堀川嫌太，清水　良，北村繁幸，太田　茂，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 核内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング
- Author(s)
  清水　良，渡部容子，浦丸直人，小島弘幸，武内伸治, 黒木広明, 太田　茂, 北村繁幸, 杉数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ラット in vivo におけるallopurinol代謝へのxanthine oxidase およびaldehyde oxidase活性の影響
- Author(s)
  田山剛崇、杉原数美、三宅勝志、北村繁幸、太田　茂
- Organizer
  第24回　日本医療薬学会年回
- Place of Presentation
  名古屋
- Year and Date
  2014-09-27 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25460235
[Presentation] 薬物代謝酵素aldehyde oxidaseのマウス肝での性差発現と化学物質の影響
- Author(s)
  杉原数美，岡嵜明穂，秋本有花，田山剛高，前田志津子，佐能正剛，北村繁幸，太田　茂
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 抗菌剤パラベン類のヒトおよびラットPXR、CAR、PPARa活性
- Author(s)
  藤野智恵里，渡部容子，浦丸直人，小島弘幸，吉成浩一，北村繁幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Comparative study on human and mouse nuclear receptor activities of hepatomegaly inducing perfluoroocatanoic acid and its related compounds.
- Author(s)
  Kojima H, Takeuchi S, Sata F, Nakajima H, Noomote T, Fujino C, Uramaru N, Kitamura S, Yoshinari K.
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Bangkok
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 香粧品香料のヒトおよびラットPXR、CAR、PPARa、AhRに対するアゴニスト活性
- Author(s)
  渡部容子，小島弘幸，浦丸直人，杉原数美, 吉成浩一, 太田　茂，北村繁幸．
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 核内受容体PXRおよびCAR転写活性に対する甲状腺ホルモン構造類似物質の影響
- Author(s)
  清水　良，渡部容子，浦丸直人，小島弘幸，武内伸治，黒木広明，太田　茂，北村繁幸，杉原数美
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 環境化学物質におけるカエル甲状腺ホルモン作用のアゴニストおよびアンタゴニスト活性
- Author(s)
  佐能正剛，中村直樹，鈴木賢一，柏木啓子，花田秀樹，山本　卓，新海　正，杉原数美，藤本成明，北村繁幸，柏木昭彦，太田　茂
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 臭素化難燃剤の甲状腺ホルモン活性－細胞依存的アゴニスト・アンタゴニスト作用
- Author(s)
  藤本成明, 松原加奈, 佐能正剛，太田　茂, 山口雅史，杉原数美，浦丸直人，北村繁幸
- Organizer
  第15回研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] レポーターアッセイ系を用いた香粧品香料によるPXR、CAR、PPARおよびAhR活性の評価
- Author(s)
  渡部容子，小島弘幸，浦丸直人，藤本成明，杉原数美，吉成浩一，太田　茂，北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] マウス肝aldehyde oxidase発現への脳下垂体の影響
- Author(s)
  秋本有花，岡嵜明穂，増岡さゆり，濱岡裕美，清水　良，佐能正剛，太田　茂，北村繁幸，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] アルデヒドオキシダーゼと薬物代謝・安全性研究
- Author(s)
  佐能正剛，田山剛高，杉原数美，北村繁幸，Mineko Terao，Enrico Garattini, 太田　茂
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響～ラットin vivoにおける検討～
- Author(s)
  田山剛高，杉原数美，三宅勝志，北村繁幸，太田茂
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ラットin vivo及びin vitroでのラズベリーケトンのロドデノールへの還元
- Author(s)
  坂本佳澄，渡部容子，浦丸直人，北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 化学物質の核内受容体活性化作用と肝肥大作用
- Author(s)
  小島弘幸，北村繁幸，浦丸直人，吉成浩一．
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Effects of neonatal exposure to thyroid hormones on gene expression profile of the pituitary-thyroid-liver in rats
- Author(s)
  Fujimoto, N., Matsubara, K., Sanoh, S., Ohta, S., Kitamura, S., Sugihara, K
- Organizer
  International Congress of Endocrinology
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] 環境中医薬品類の塩素消毒による毒性発現
- Author(s)
  杉原数美，高田　鑑，増田莉奈，大上　凌，小林秀文，清水　良，北村繁幸，太田　茂
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸
- Year and Date
  2014-07-02 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ピレスロイド系およびカルバメート系農薬のラットPXR、CARおよびPPARa活性と肝代謝による影響
- Author(s)
  藤野智恵里，渡部容子，浦丸直人，小島弘幸，吉成浩一，北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds
- Author(s)
  Kojima H., Sanoh S., Takeuchi S., Sugihara K., Yoshinari K., Kitamura S.
- Organizer
  54th Annual Meeting and ToxExpo (Society of Toxicology)
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2015-03-22 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] 医薬品の塩素処理による分解と変異原性発現
- Author(s)
  藤田哲孝，泉　哲平，三好晃史，清水　良，小林秀文，北村繁幸，太田　茂，杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25340049
[Presentation] ラット肝での新規甲状腺ホルモン応答遺伝子pdxkの同定とプロモーター解析
- Author(s)
  藤本成明, 松原加奈, 佐能正剛，太田　茂，北村繁幸
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23510076
[Presentation] Metabolic activation of cis- and trans- permethrine for estrogenic and anti-androgenic activities
- Author(s)
  Sugihara K.,Tange N., Fujimoto N., Uramaru N., Ohta S., Kitamura S.
- Organizer
  DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-08-31 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25340049

1. SUGIHARA Kazumi (20271067)

# of Collaborated Projects: 20 results

# of Collaborated Products: 202 results
2. OHTA Shigeru (60160503)

# of Collaborated Projects: 14 results

# of Collaborated Products: 108 results
3. FUJIMOTO Nariaki (40243612)

# of Collaborated Projects: 10 results

# of Collaborated Products: 94 results
4. YOSHIHARA Shinichi (00037607)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. SANOH Seigo (00552267)

# of Collaborated Projects: 3 results

# of Collaborated Products: 40 results
6. NISHIJIMA Wataru (20243602)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
7. KASHIWAGI Akihiko (50106796)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. WATANABE Hiromitu (00034653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. URAMARU Naoto (90424069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 56 results
10. SHIMIZU RYOU (00570491)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
11. Tayama Yoshitaka (80389121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. TANIGUCHI Yoshihiko (30403520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KOJIMA Hiroyuki (10414286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
14. NAKAMURA Shigenobu (30026843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ARIZONO Koji (70128148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMASHITA Keisuke (40166666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KOTAKE Yaichiro (20335649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. TASHIRO Tomoko (50114541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TATSUMI Kiyoshi (90037581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渡部容子 (60628056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
21. MIYAGAWA Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. TSUKAMOTO Toyohisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. SUZUKI Go

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. HORIGUCHI Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. TAKEUCHI Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
26. 井口泰泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 前田志津子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 佐々木崇光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 今岡進

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 岡田和嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kitamura shigeyuki 北村 繁幸

KITAMURA Shigeyuki 北村 繁幸

KITAMURA/SHIGEYUKI 北村 繁幸

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Influence of chemicals used in consumer products on endocrine-system via activation of nuclear receptorsPrincipal Investigator

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Estimation of target proteins of hydroxylated PCB and brominated flame retardants for thyroid hormone disruption and the influence by radiationPrincipal Investigator

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Determination of targets for thyroid hormone disruption by brominated flame retardantsPrincipal Investigator

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Formation of Hydroxylated Metabolites Responsible for the Toxicity of Brominated Flame Retardants and Thyroid Hormone Disrupting ActionPrincipal Investigator

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Thyroid hormone-disrupting activity of brominated retardants and hydroxylated PCBsPrincipal Investigator

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kitamura shigeyuki 北村繁幸

KITAMURA Shigeyuki 北村繁幸

KITAMURA/SHIGEYUKI 北村繁幸