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Sugihara kazumi  杉原 数美

ORCIDConnect your ORCID iD *help
… Alternative Names

SUGIHARA Kazumi  杉原 数美

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Researcher Number 20271067
Other IDs
External Links
Affiliation (Current) 2020: 広島国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2012 – 2019: 広島国際大学, 薬学部, 教授
2012: 広島国際大学, 薬学部
2009 – 2011: Hiroshima International University, 薬学部, 准教授
2010: 広島大学, 医歯薬総合研究科, 准教授
2008: Hiroshima University, 医歯薬学総合研究科, 准教授 … More
2007: Hiroshima University, Graduate School of Biomedical Sciences, Assistant Professor
2006: 広島大学, 大学院理学研究か, 助教
2006: Hiroshima University, Faculty of Pharmacy, Teaching Associate, 薬学部, 教務員
1998 – 2005: 広島大学, 医学部, 教務員 Less
Review Section/Research Field
Principal Investigator
Environmental pharmacy / Environmental and hygienic pharmacy
Except Principal Investigator
Environmental pharmacy / Medical pharmacy / Drug development chemistry / Risk sciences of radiation/Chemicals / Risk sciences of radiation and chemicals / 医薬分子機能学 / Neurochemistry/Neuropharmacology / Environmental pharmacy / Science and Engineering / Basic Section 47060:Clinical pharmacy-related
Keywords
Principal Investigator
医薬品 / 環境汚染 / 生態毒性 / 太陽光 / 紫外線 / 環境因子 / 変異原性 / 東アジア / 医薬品汚染 / 大韓民国 … More / 生態系毒性 / 環境動態 / 環境保全リーダー育成 / ダイオキシン / 副腎皮質ホルモン / 内分泌撹乱化学物質 / 糖質コルチコイド / Dioxin / Adrenal cortex hormone / Endocrine disrupters / Glucocorticoid / 病院下水 / 下水処理 / 生態影響 / Pharmaceuticals / Environmental pollution / Hospital sewage / Effect to ecosystem / 性差 / 薬物代謝酵素 / 成長ホルモン / 内分泌かく乱物質 / 薬毒物代謝酵素 / 転写制御 / ホルモン / 系統差 / シトクロムP450 / アルデヒドオキシダーゼ / エピジェネティクス … More
Except Principal Investigator
代謝的活性化 / パーキンソン病 / テトラヒドロイソキノリン / 神経毒 / ブロム化難燃剤 / Parkinson's disease / 甲状腺ホルモン / tetrahydroisoquinoline / 内分泌撹乱物質 / 内分泌撹乱 / 水酸化代謝物 / 核内受容体 / 内分泌撹乱作用 / 薬物代謝酵素 / パーキンソン病発症物質 / ドーパミン神経 / Endocrine disruptor / Metabolic activation / パーキンソニズム / テトラハイドロイソキノリン / P糖タンパク質 / カリブ諸島 / 甲状腺ホルモン撹乱 / 薬学 / 医療薬学 / ニコチン製剤 / 禁煙治療 / パーキンソン病防御物質 / 細胞培養 / Parkinson's disease causing substance / 内分泌撹乱前駆物質 / エストロゲン / ビテロゲニン / neurotoxin / Environmental pollutant / 1MeTIQ / P-glycoprotein / オタマジャクシ / 変態 / Thyroid hormonal activity / Tetrabromobisphenol A / Brominated flame retardant / parkinsonism / 内分泌撹乱活性 / エストロゲン活性 / 異物代謝 / ビスフェノールA / アルキルフェノール類 / ベンゾフェノン類 / 抗アンドロゲン活性 / プロエストロゲン / 異物代謝酵素 / フェンチオン / 2-ニトロフルオレン / 内分泌攪乱物質 / 異物(薬物)代謝酵素 / アルキルフェノール / 大豆イソフラボン / β-チューブリン / ユビキチン化 / チューブリン / parkin / ユビキチン化阻害 / Parkin / 熱帯風土病 / パーキンソン病関連疾患 / イソキノリンアルカロイド / P糖タンパ / 地域特異的神経変性疾患 / トゲバンレイシ / バーキンソン病類縁疾患 / 天然物化学 / 構造決定 / アルカロイド / パーキンソン病モデル動物 / 内分泌かく乱物質 / 子供の環境リスク / 甲状腺ホルモン応答遺伝子 / 発達期影響 / 新生児期曝露 / プロム化難燃剤 / 甲状腺ホメオスタシス / プロテインジスルフィッドイソメラーゼ / 核内レセプター / プロテインジスルフィドイソメラーゼ / ヒト肝細胞移植キメラマウス / 化学物質 / リスク評価 / 薬物動態 / 薬物代謝 / PCB / 甲状腺ホルモン代謝 / 甲状腺ホルモン受容体 / nicotine / aldehyde oxidase / CYP2A6 / ニコチン / 医薬品汚染 / 医薬品曝露 / 医薬品粉じん / 後発医薬品 / 散剤調剤 / 帯電量 / 錠剤粉砕 / 環境汚染 / Parkinson's disease cpreventing substance / dopaminergic neuron / cell culture / 早期診断技術 / アルデヒドオキシターゼ / アルデヒドオキシダーゼ / early marker / aldehydeoxidase / トランスースチルベン / ビフェニール / トランス-スチルベン / トランスースチルベンオキシド / endocrine disruptor / proestrogen / estrogen / metabolic activation / vitellogenin / trans-stilbene / biphenyl / drug metabolizing enzyme / ディファレンシャルディスプレイ / cDNAマイクロアレイ / アポトーシス関連遺伝子 / NMDAレセプター / アポトーシス / differential display / apoptosis / cDNA microaray / 抗アンドロゲン / 甲状腺ホルモン様物質 / 環境汚染物質 / 甲状腺ホルモン撹乱物質 / Estrogen / Antiandrogen / Thyroid hormonal compound / Vitellogenin / Drug metabolizing enzyme / サルゾリノール / 代謝変換 / 1ベンジルTIQ / ミトコンドリア呼吸鎖阻害 / 細胞培養系 / tetrahydroisogunoline / anti-parkinsonian drug / structure-activity relationship / テトラヒドロイソキノリン類 / 遺伝子発現調節 / テトラヒドロイソキノリン酸 / tetrahydroisoguinoline / drug transporter / expression level / 水酸化PCB / アゴニスト作用 / 甲状腺ホルモン様作用 / テチラbyリノブスフェノールA / アンタゴニスト / Hydroxylated PCB / Tadpole tail regression / P糖蛋白質 / プロドラッグ / neurotxin / prodrug / サワーソップ / Annonaceae / Caribbean islands / 臭素化難燃剤 / 甲状腺ホルモン活性 / 両生類 / ポリブロモジフェニールエーテル / Polybromodiphenyl ether / Estrogenic activity / Amphibian metamorphosis / 環境化学物質 / 生活用品 / シトクロムP450 / 生活関連化学物質 / 紫外線吸収剤 / リン系難燃剤 / 殺菌剤パラベン / 残留性農薬 / 代謝活性化 / 殺菌料パラベン / nicotine製剤 / 投与設計 / 代謝酵素 / 高尿酸血症 / キサンチンオキシダーゼ / xanthine oxidase / uric acid / circadian rhythm Less
  • Research Projects

    (28 results)
  • Research Products

    (298 results)
  • Co-Researchers

    (27 People)
  •  Control of uric acid by considering the change xanthine oxidase activity with the circadian rhythmOngoing

    • Principal Investigator
      田山 剛崇
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Hiroshima International University
  •  Epigenetic regulation of sex-specific gene expression and investigation of the effects of environmental chemicals and drugsPrincipal Investigator

    • Principal Investigator
      sugihara kazumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      Hiroshima International University
  •  Influence of chemicals used in consumer products on endocrine-system via activation of nuclear receptors

    • Principal Investigator
      Kitamura Shigeyuki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Nihon Pharmaceutical University
  •  Appropriate administration of nicotine according to the metabolic enzyme activity estimated from the nicotine metabolites in saliva.

    • Principal Investigator
      Tayama yoshitaka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Hiroshima International University
  •  Investigation of the Pharmaceutical pollution in the pharmacy and the health impact assessment of occupational exposure

    • Principal Investigator
      MAEDA SHIZUKO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Hiroshima International University
  •  Estimation of target proteins of hydroxylated PCB and brominated flame retardants for thyroid hormone disruption and the influence by radiation

    • Principal Investigator
      Kitamura Shigeyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Nihon Pharmaceutical University
  •  Estimation for the adequate dose of nicotine by using the ratio of the metabolites in urine

    • Principal Investigator
      Tayama Yoshitaka
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Hiroshima International University
  •  Determination of targets for thyroid hormone disruption by brominated flame retardants

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nihon Pharmaceutical University
  •  Risk assessment of chemicals using chimeric mice with humanized liver

    • Principal Investigator
      OHTA SHIGERU
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University
  •  Study of PPCPs in Eastern Asian countriesPrincipal Investigator

    • Principal Investigator
      SUGIHARA Kazumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima International University
  •  Pathogenetic mechanism of sporadic Parkinson's disease based on familial Parkinson's disease

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University
  •  Drug development using novel animal model based on the pathogenesis of Parkinson' s disease-related disorders

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hiroshima University
  •  Effects of neonatal exposure to thyroid hormone disrupting chemicals in rats

    • Principal Investigator
      FUJIMOTO Nariaki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Hiroshima University
  •  Study of environmental pollution by pharmaceuticals and effect of environmental factors on the toxicity.Principal Investigator

    • Principal Investigator
      SUGIHARA Kazumi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University
  •  Development of anti-Parkinson's disease drugs using P-glycoprotein knockout mice heated with endogenous neurotoxin.

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hiroshima University
  •  Integrated analysis of environmental and genetic factors against Caribbean parkinsonism

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University
  •  Formation of Hydroxylated Metabolites Responsible for the Toxicity of Brominated Flame Retardants and Thyroid Hormone Disrupting Action

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Nihon Pharmaceutical University
  •  Pharmaceuticals in hospital sewages and their toxicities to ecosystemPrincipal Investigator

    • Principal Investigator
      SUGIHARA Kazumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Parkinsonism-inducing mechanism by endogenous multifunctional neurotoxins in the brain

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Thyroid hormone-disrupting activity of brominated retardants and hydroxylated PCBs

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Development of anti-parkinsonian drug using structure-activity relationship

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  内分泌攪乱物質並びにその前駆物質の代謝変換とホルモン作用の修飾

    • Principal Investigator
      YOSHIHARA Shinichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hiroshima University
  •  Metabolic activation of endocrine-disruptors in animal body

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental pharmacy
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Effect of Dioxin and Endocrine disrupters on Adrenal HormonePrincipal Investigator

    • Principal Investigator
      SUGIHARA Kazumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Institution
      Hiroshima University
  •  Research for the Parkinson's disease related proteins using endogenous neurotoxins

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Metabolism and endocrine disrupting action of environmental pollutants

    • Principal Investigator
      KITAMURA Shigeyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hiroshima University School of Medicine
  •  Investigation of Parkinson's disease causing substances

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Hiroshima University
  •  Early markers of Parkinson's disease

    • Principal Investigator
      OHTA Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Hiroshima University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Organophocphates as endocrine disruptors' in 'Anticholinesterase Pesticides'2011

    • Author(s)
      Kitamura, Shigeyuki; Sugihara, Kazumi; Fujimoto, Nariaki; Yamazaki, Takeshi
    • Publisher
      Wiley Edited by Satoh, Tetsuo : Gupta, Ramesh C
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Book] in Anticholinesterase pesticides.(Organophosphates as Endocrine Disruptor)2010

    • Author(s)
      Kitamura S., Sugihara K., Fujimoto N., Yamazaki T.
    • Total Pages
      14
    • Publisher
      Wiley and Sons Ltd
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Book] T. Satoh, R. C. Gupta(ed.) Anticholinesterase Pesticides, John Wiley & Sons, Ltd, Hoboken, NJ2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Publisher
      Organophosphates asendocrine disruptors In
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Book] Organophosphates as Endocrine Disruptor in Anticholinesterase pesticides2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Book] Anticholinesterase Pesticides : Organophosphates as Endocrine Disruptors2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Total Pages
      21
    • Publisher
      John Wiley & Sons, Ltd, Hoboken
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Total Pages
      14
    • Publisher
      Johan Wiley and Sons Ltd.
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Book] Organophosphates as Endocrine Disruptor, in Anticholinesterase pesticides.2010

    • Author(s)
      Kitamura, S., Sugihara, K., Fujimoto, N., Yamazaki, T.
    • Total Pages
      14
    • Publisher
      Johan Wiley and Sons Ltd.
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009

    • Author(s)
      Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
    • Total Pages
      15
    • Publisher
      Johan Wiley and Sons Ltd
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Book] General and Applied Toxicology III Endocrine Disruption in Toxic Responses2009

    • Author(s)
      Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
    • Total Pages
      44
    • Publisher
      John Wiley & Sons, Ltd, Chichester
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Book] Endocrine Disruption in Toxic Responses, B. Ballantyne, T. Marrs, T. Syversen(ed.) General and AppliedToxicology III, John Wiley & Sons, Ltd, Chichester2009

    • Author(s)
      Kitamura, S., Sugihara, K., Nakamura, K., Kotake, K., Kashiwagi, A., Fujimoto, N.
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009

    • Author(s)
      Kitamura, Shigeyuki ; Sugihara, Kazumi ; Nakamura, Kazuo ; Yaichiro Kotake ; Kashiwagi, Akihiko ; Fujimoto, Nariaki
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Book] Endocrine Disruption in Toxic Responses. In Ballantyne Bryan(ed), the 3rd Edition of General and Applied Toxicology2009

    • Author(s)
      Kitamura, Shigeyuki, Sugihara, Kazumi, Nakamura, Kazuo, Yaichiro Kotake, Kashiwagi, Akihiko, Fujimoto, Nariaki
    • Total Pages
      15
    • Publisher
      Johan Wiley and Sons Ltd
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Book] THYROID HORMONAL AND ESTROGENIC ACTIVITIES OF HYDROXYLATED PCB AND BROMINATED FLAME RETARDANT IN CELL CULTURE, JME2008

    • Author(s)
      Kitamura Shigeyuki, Sugihara, Kazumi, et al.
    • Publisher
      POPS in Asia
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Book] SCREENING OF AhR-BINDING, ESTROGENIC AND ANTIANDROGENIC ACTIVITIES OF BENZOPHENONE DERIVATIVES USED AS UV STABILIZERS AND SUNSCREENS.2008

    • Author(s)
      Sugihara Kazumi
    • Publisher
      POPs in Asia
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Book] SCREENING OF AhR-BINDING, ESTROGENIC AND ANTIANDROGENIC ACTIVITIES OF BENZOPHENONE DERIVATIVES USED AS UV STABILIZERS AND SUNSCREENS2008

    • Author(s)
      Sugihara, Kazumi, et al.
    • Publisher
      JME, POPs in Asia
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Profiling of bisphenol A and eight of its analogues on transcriptional activity via human nuclear receptors2019

    • Author(s)
      Hiroyuki Kojima, Shinji Takeuchi, Seigo Sanoh, Katsuhiro Okuda, Shigeyuki Kitamura, Naoto Uramaru, Kazumi Sugihara, Kouichi Yoshinari
    • Journal Title

      Toxicology

      Volume: 413 Pages: 48-55

    • DOI

      10.1016/j.tox.2018.12.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17K15493, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-16K00559
  • [Journal Article] Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactionsl2018

    • Author(s)
      Naoki Takaoka; Seigo Sanoh; Katsuhiro Okuda; Yaichiro Kotake; Go Sugahara; Ami Yanagi; Yuji Ishida; Chise Tateno;Yoshitaka Tayama; Kazumi Sugihara; Shigeyuki Kitamura; Mami Kurosaki; Mineko Terao; Enrico Garattini; Shigeru Ohta
    • Journal Title

      Biochem. Pharmacol.

      Volume: 154 Pages: 28-38

    • DOI

      10.1016/j.bcp.2018.04.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-16K00559
  • [Journal Article] Aryl Hydrocarbon Receptor Ligand Activity of Extracts from 62 Herbal Medicines and Effect on Cytochrome P450 Activity2018

    • Author(s)
      Harada A., Sugihara K., Watanabe Y., Yamaji S., Kitamura S., Ohta S.
    • Journal Title

      薬学雑誌

      Volume: 135 Issue: 10 Pages: 1185-1196

    • DOI

      10.1248/yakushi.15-00153

    • NAID

      130005100636

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2018-08-31
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Journal Article] Effect of Environmental Factors on the Ecotoxicity of Pharmaceuticals and Personal Care Products2018

    • Author(s)
      Kazumi Sugihara
    • Journal Title

      薬学雑誌

      Volume: 138 Issue: 3 Pages: 277-280

    • DOI

      10.1248/yakushi.17-00177-2

    • NAID

      130006410646

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Journal Article] Inhibitory effects of drugs on the metabolic activity of mouse and human aldehyde oxidases and influence on drug-drug interactions2018

    • Author(s)
      Naoki Takaoka; Seigo Sanoh; Katsuhiro Okuda;Yaichiro Kotake; Go Sugahara; Ami Yanagi; Yuji Ishida; Chise Tateno;Yoshitaka Tayama; Kazumi Sugihara; Shigeyuki Kitamura; Mami Kurosaki; Mineko Terao; Enrico Garattini; Shigeru Ohta
    • Journal Title

      Biochem. Pharmacol.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Journal Article] Developmental changes in drug-metabolizing enzyme expression during metamorphosis of <i>Xenopus tropicalis </i>2017

    • Author(s)
      Mori J., Sanoh S., Kashiwagi K., Hanada H., Shigeta M., Suzuki K., Yamamoto T., Kotake Y., Sugihara K., Kitamura S., Kashiwagi A., Ohta S.
    • Journal Title

      J. Toxicol. Sci.

      Volume: 42 Issue: 5 Pages: 605-613

    • DOI

      10.2131/jts.42.605

    • NAID

      130006076698

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17J02822
  • [Journal Article] Comparative study of hydrolytic metabolism of dimethyl phthalate, dibutyl phthalate and di(2-ethylhexyl) phthalate by microsomes of various rat tissues2017

    • Author(s)
      Ozaki H., Sugihara K., Watanabe Y., Moriguchi K., Uramaru N., Sone T., Ohta S., Kitamura S.
    • Journal Title

      Food Chem Toxicol.

      Volume: 100 Pages: 217-224

    • DOI

      10.1016/j.fct.2016.12.019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
  • [Journal Article] Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene2017

    • Author(s)
      Tanoue C., Sugihara K., Tayama Y., Uramaru N., Watanabe Y., Ohta S., Kitamura S.
    • Journal Title

      Drug Metab Lett.

      Volume: 10 Pages: 278-285

    • DOI

      10.2174/1872312810666161227145358

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K00559, KAKENHI-PROJECT-17K08401
  • [Journal Article] In vitro metabolism of methiocarb and carbaryl in rats, and its effect on their estrogenic and antiandrogenic activities.2016

    • Author(s)
      Tange S., Fujimoto N., Uramaru N., Wong F. F., Sugihara K., Ohta S., Kitamura S.
    • Journal Title

      Environ Toxicol Pharmacol.

      Volume: 41 Pages: 289-297

    • DOI

      10.1016/j.etap.2015.08.014

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-16K00559
  • [Journal Article] Estimation of occupational exposure to drugs during tablet crushing.2016

    • Author(s)
      Shizuko Maeda, Eiko Takahashi, Yoshitaka Tayama, Shigeyuki Kitamura, Toyohisa Tsukamoto, Katsushi Miyake, Kazumi Sugihara.
    • Journal Title

      Fundamental Toxicological Sciences

      Volume: 3 Pages: 177-183

    • NAID

      130005158221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Journal Article] Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products2016

    • Author(s)
      Hitomi Ozaki, Kazumi Sugihara, Yoko Watanabe, Shigeru Ohta, Shigeyuki Kitamura .
    • Journal Title

      J. Toxicol. Sci.

      Volume: 41 Issue: 4 Pages: 551-560

    • DOI

      10.2131/jts.41.551

    • NAID

      130005165024

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Journal Article] Estimation of occupational exposure to drugs during tablet crushing2016

    • Author(s)
      Shizuko Maeda , Eiko Takahashi , Yoshitaka Tayama , Shigeyuki Kitamura , Toyohisa Tsukamoto , Katsushi Miyake , Kazumi Sugihara
    • Journal Title

      Fundam. Toxicol. Sci.

      Volume: 3 Issue: 4 Pages: 177-183

    • DOI

      10.2131/fts.3.177

    • NAID

      130005158221

    • ISSN
      2189-115X
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460247, KAKENHI-PROJECT-16K08428
  • [Journal Article] Predictability of plasma concentration-time curves in humans using single-species allometric scaling of chimeric mice with .humanized liver2015

    • Author(s)
      Sanoh S., Naritomi Y., Fujimoto M., Sato K., Kawamura A., Horiguchi A., Sugihara K., Kotake Y., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S.
    • Journal Title

      Xenobiotica

      Volume: 45 Pages: 605-614

    • DOI

      10.3109/00498254.2015.1007112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Journal Article] Hydrolytic metabolism of phenyl and benzyl salicylates, fragrances and flavoring agents in foods, by microsomes of rat and human tissues2015

    • Author(s)
      Ozaki H., Sugihara K., Tamura Y., Fujino C., Watanabe Y., Uramaru N., Sone T., Ohta S., Kitamura S.
    • Journal Title

      Food Chem Toxicol

      Volume: 86. Pages: 116-123

    • DOI

      10.1016/j.fct.2015.08.024

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Journal Article] Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.2015

    • Author(s)
      Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Seigo Sanoh, Kazumi Sugihara, Shigeyuki Kitamura, and Shigeru Ohta
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 282 Pages: 119-128

    • DOI

      10.1016/j.taap.2014.12.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
  • [Journal Article] Significance of aldehyde oxidase during drug development: Effects on drug metabolism, pharmacokinetics, toxicity, and efficacy.2015

    • Author(s)
      Sanoh, S., Tayama Y., Sugihara K., Kitamura S., Ohta S.
    • Journal Title

      Drug Metab. Pharmacokinet

      Volume: 30 Pages: 52-63

    • DOI

      10.1016/j.dmpk.2014.10.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Journal Article] Current stutus of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver2014

    • Author(s)
      Kitamura S. and Sugihara K.
    • Journal Title

      Xenobiotica

      Volume: 44 Pages: 123-134

    • DOI

      10.3109/00498254.2013.868062

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Journal Article] 2,5-Dihydroxy-4-methoxybenzophenone: a novel major in vitro metabolite of benzophenone-3 formed by rat and human liver microsomes.2014

    • Author(s)
      Kamikyouden N., Sugihara K., Watanabe Y., Uramaru N., Murahashi T., Kuroyanagi M., Sanoh S., Ohta S., Kitamura S
    • Journal Title

      Xenobiotica.

      Volume: 43(6) Pages: 514-519

    • DOI

      10.3109/00498254.2012.742217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053, KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
  • [Journal Article] In vitro metabolism of cis- and trans-permethrin by rat liver microsomes, and its effect on estrogenic and anti-androgenic activities.2014

    • Author(s)
      Tange, S., Fujimoto, N., Uramaru, N., Sugihara, K., Ohta, S., Kitamura, S
    • Journal Title

      Environ Toxicol Pharmacol.

      Volume: 37 Pages: 996-1005

    • DOI

      10.1016/j.etap.2014.03.009

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
  • [Journal Article] Fluorometric assessment of acetaminophen-induced toxicity in rat hepatocyte spheroids seeded on micro-space cell culture plates.2014

    • Author(s)
      Sanoh S, Santoh M, Takagi M, Kanayama T, Sugihara K, Kotake Y, Ejiri Y, Horie T, Kitamura S, Ohta S
    • Journal Title

      Toxicology in Vitro

      Volume: (in press) Pages: 192-197

    • DOI

      10.1016/j.tiv.2014.05.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-25340049
  • [Journal Article] Strain Difference of Oxidative Metabolism of the Sedative-hypnotic Zaleplon by Aldehyde Oxidase and Cytochrome P450 <i>In Vivo</i> and <i>In Vitro</i> in Rats2013

    • Author(s)
      Tanoue C., Sugihara K., Uramaru N., Watanabe Y., Tayama Y., Ohta S., Kitamura S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 28(3) Issue: 3 Pages: 269-273

    • DOI

      10.2133/dmpk.dmpk-12-nt-103

      10.2133/dmpk.DMPK-12-NT-103

    • NAID

      130004463299

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Journal Article] Strain Difference of Oxidative Metabolism of the Sedative-Hypnotic Zaleplon byAldehyde Oxidase and Cytochrome P450 in Vivo and in Vitro in Rats.2013

    • Author(s)
      Tanoue C, Sugihara K, Uramaru N, Watanabe Y, Tayama Y, Ohta S, Kitamura S.
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: In Press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Journal Article] Comparative study of the hydrolytic metabolism of methyl-, ethyl-, propyl-, butyl-, heptyl- and dodecylparaben by microsomes of various rat and human tissues2013

    • Author(s)
      Ozaki H., Sugihara K., WatanabeY., Fujino C., Uramaru N., Sone T., Ohta S., Kitamura S
    • Journal Title

      Xenobiotica

      Volume: (in press) Pages: 1064-1072

    • DOI

      10.3109/00498254.2013.802059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
  • [Journal Article] Strain difference of oxidative metabolism of the sedative-hypnotic zaleplon by aldehyde oxidase and cytochrome P450 in vivo and in vitro in rats2013

    • Author(s)
      Tanoue C, Sugihara K, Uramaru N, Watanabe Y, Tayama Y, Ohta S, Kitamura S
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 28(3) Pages: 269-73

    • NAID

      130004463299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Journal Article] Photodegradation of pharmaceuticals in the aquatic environment by sunlight and UV-A, -B and -C irradiation2013

    • Author(s)
      Kawabata K., Sugihara K., Sanoh S., Kitamura S., Ohta S
    • Journal Title

      J. Toxicol. Sci.

      Volume: 38(2) Issue: 2 Pages: 215-223

    • DOI

      10.2131/jts.38.215

    • NAID

      10031151425

    • ISSN
      0388-1350, 1880-3989
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126
  • [Journal Article] Cell type-dependent agonist/antagonist activities of polybrominated diphenyl ethers.2013

    • Author(s)
      Nakamura N, Matsubara K, Sanoh S, Ohta S, Uramaru N, Kitamura S, Yamaguchi M, Sugihara K, Fujimoto N
    • Journal Title

      Toxicology Letters

      Volume: 223(2) Pages: 192-197

    • DOI

      10.1016/j.toxlet.2013.09.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
  • [Journal Article] Prediction of human metabolism of the sedative-hypnotic zaleplon using chimeric mice transplanted with human hepaticytes2013

    • Author(s)
      Tanoue C., Sugihara K., Uramaru N., Tayama Y., Watanabe Y., Horie T., Ohta S., Kitamura S
    • Journal Title

      Xenobiotica

      Volume: (in press) Pages: 956-962

    • DOI

      10.3109/00498254.2013.788232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
  • [Journal Article] Developmental Changes of Aldehyde Oxidase Activity and Protein Expression in Human Liver Cytosol2012

    • Author(s)
      Tayama Y., Sugihara K., Sanoh S., Miyake K., Kitamura S., Ohta S.
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 27 Issue: 5 Pages: 543-547

    • DOI

      10.2133/dmpk.dmpk-11-nt-124

      10.2133/dmpk.DMPK-11-NT-124

    • NAID

      130004463273

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23790212
  • [Journal Article] Effects of polybrominated diphenyl ethers (PBDEs) and their derivatives on protein disulfide isomerase activity and growth hormone release of GH3 cells2012

    • Author(s)
      Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S, and Imaoka S.
    • Journal Title

      Chem. Res. Toxicol

      Volume: 25(3) Pages: 656-63

    • DOI

      10.1021/tx200374s

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310045, KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23655162
  • [Journal Article] Prediction of in vive hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012

    • Author(s)
      Sanoh, Seigo ; Horiguchi, Aya ; Sugihara, Kazumi ; Kotake, Yaichiro ; Tayama, Yoshitaka ; Ohshita, Hiroki ; Tate noo, Chise ; Horie, Toni ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism & Disposition

      Volume: 40(2) Pages: 322-328

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effects of Polybrominated Diphenyl Ethers(PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012

    • Author(s)
      Hashimoto, Shako ; Yoshimura, Hiromi ; Okada, Kazushi ; Uramaru, Naoto ; Sugihara, Kazumi ; Kitamura, Shigeyuki ; Imaoka, Susumu
    • Journal Title

      Chemical Research in Toxicology

      Volume: 25(3) Pages: 656-663

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara K., Sanoh S., Ohta S., Kitamura S., Fujimoto N
    • Journal Title

      Toxicol. Lett

      Volume: 208 Pages: 30-35

    • DOI

      10.1016/j.toxlet.2011.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23510076
  • [Journal Article] Animproved thyroid hormone reporter assay to determine the thyroid hormone-likeactivity of amiodaronebithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara K., Sanoh S., Ohta S., Kitamura S., Sugihara K., Fujimoto N.
    • Journal Title

      Toxicol. Lett

      Volume: 208 Pages: 30-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Journal Article] Prediction of In Vivo Hepatic Clearance and Half-life of Drug Candidates in Human using Chimeric Mice with Humanized Liver.2012

    • Author(s)
      Sanoh S., Horiguchi A., Sugihara K., Kotake Y., Tayama Y., Uramaru N., Ohshita H., Tateno C., Horie T., Kitamura S., Ohta S
    • Journal Title

      Drug Metabolism and Disposition

      Volume: 40(2) Pages: 2267-2272

    • DOI

      10.1124/dmd.111.040923

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-22790109, KAKENHI-PROJECT-23310047, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053
  • [Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara, Kana ; Sanoh, Seigo ; Ohta, Shigeru ; Kitamura, Shigeyuki ; Sugihara, Kazumi ; Fujimoto, Nariaki
    • Journal Title

      Toxicology Letters

      Volume: 208(1) Pages: 30-35

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Predictability of metabolism of Ibuprofen and naproxen using chimeric mice with human hepatocytes.2012

    • Author(s)
      Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Uramaru N, Ohshita H, Tateno C, Horie T, Kitamura S, Ohta S
    • Journal Title

      Drug Metab Dispos.

      Volume: 40(12) Pages: 2267-2272

    • DOI

      10.1124/dmd.112.047555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310047, KAKENHI-PROJECT-23390030, KAKENHI-PROJECT-23659053, KAKENHI-PROJECT-24651061, KAKENHI-PROJECT-24790111, KAKENHI-PROJECT-24790126
  • [Journal Article] An improved thyroid hormone reporter assay to determine the thyroid hormone-like activity of amiodarone, bithionol, closantel and rafoxanide2012

    • Author(s)
      Matsubara K, Sanoh S, Ohta S, Kitamura S, Sugihara K, Fujimoto N
    • Journal Title

      Toxicol Lett

      Volume: 208 Pages: 30-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effects of Polybrominated Diphenyl Ethers (PBDEs) and Their Derivatives on Protein Disulfide Isomerase Activity and Growth Hormone Release of GH3 Cells2012

    • Author(s)
      Hashimoto S, Yoshimura H, Okada K, Uramaru N, Sugihara K, Kitamura S
    • Journal Title

      Chem Res Toxicol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver2012

    • Author(s)
      Sanoh S, Horiguchi A, Sugihara K, Kotake Y, Tayama Y, Ohshita H
    • Journal Title

      Drug Metab Dispos

      Volume: 40 Pages: 322-328

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Ultraviolet-photoproduct of acetaminophen: Structure determination and evaluation of ecotoxicological effect.2012

    • Author(s)
      Kawabata K., Sugihara K., Sanoh S., Kitamura S.,Ohta S
    • Journal Title

      J Photochem Photobiol A Chem

      Volume: 249 Pages: 29-35

    • DOI

      10.1016/j.jphotochem.2012.07.018

    • Data Source
      KAKENHI-PROJECT-22510071
  • [Journal Article] Effect oftea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, MiyakeK, Morita S, Kitamura S, Ohta S.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 26 Pages: 94-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 26 Pages: 94-101

    • NAID

      130004463166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama Yoshitaka ; Sugihara Kazumi ; Sanoh Seigo ; Miyake Katsushi ; Morita Shushi ; Kitamura Shigeyuki ; Ohta Shy
    • Journal Title

      Drug Metabolism and Pharmacokinetics 26(1)

      Pages: 94-101

    • NAID

      130004463166

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity2011

    • Author(s)
      Tayama, Yoshitaka ; Sugihara, Kazumi ; Sanoh, Seigo ; Miyake, Katsushi ; Marita, Shushi ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 26(1) Pages: 94-101

    • NAID

      130004463166

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effect of Tea Beverages on Aldehyde Oxidase Activity2011

    • Author(s)
      Tayama Y., Sugihara K., Sanoh S., Miyake K., Morita S., Kitamura S., Ohta S
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 26(1) Issue: 1 Pages: 94-101

    • DOI

      10.2133/dmpk.dmpk-10-nt-078

      10.2133/dmpk.DMPK-10-NT-078

    • NAID

      130004463166

    • ISSN
      1347-4367, 1880-0920
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010

    • Author(s)
      Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
    • Journal Title

      Drug Metab.Pharmacokinet. 25

      Pages: 262-273

    • NAID

      10027582853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010

    • Author(s)
      Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 25(3) Pages: 262-273

    • NAID

      10027582853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] 在宅で発生する向精神薬等取扱注意医薬品の残薬処理の実態調査2010

    • Author(s)
      杉原数美
    • Journal Title

      有害・医療廃棄物研究

      Volume: 22(2) Pages: 82-85

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010

    • Author(s)
      Nurrochmad, Ariel ; Ishii, Yuji ; Nakanoh, Hitomi ; Inoue, Tae ; Horie, Torn ; Sugihara, Kazumi ; Ohta, Shigeru ; Taketomi, Akinobu ; Maehara, Yoshihiko ; Yamada, Hideyuki
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 25(3) Pages: 262-373

    • NAID

      10027582853

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S.
    • Journal Title

      Drug Metab.Pharmacokinet. 26

      Pages: 94-101

    • NAID

      130004463166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] 在宅で発生する向精神薬等取扱注意医薬品の残薬処理の実態調査2010

    • Author(s)
      杉原数美
    • Journal Title

      有害・医療廃棄物研究

      Volume: 22(2) Pages: 82-85

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver.2010

    • Author(s)
      Nurrochmad A, Ishii Y, Nakanoh H, Inoue T, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 25(3) Pages: 262-273

    • NAID

      10027582853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010

    • Author(s)
      Nurrochmad A, Ishii Y, Nakanoh H, InoueT, Horie T, Sugihara K, Ohta S, Taketomi A, Maehara Y, Yamada H.
    • Journal Title

      Drug MetabPharmacokinet

      Volume: 25 Pages: 262-273

    • NAID

      10027582853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity : a comparative study in humans and rodents including chimeric mice carrying human liver2010

    • Author(s)
      Nurrochmad Arief ; Ishii Yuji ; Nakanoh Hitomi ; Inoue Tae ; Horie Toru ; Sugihara Kazumi ; Ohta Shigeru ; Taketomi Akinobu ; Maehara Yoshihiko ; Yamada Hideyuki
    • Journal Title

      Drug Metabolism and Pharmacokinetics 25(3)

      Pages: 262-273

    • NAID

      10027582853

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 26(1) Pages: 94-101

    • NAID

      130004463166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effect of tea beverages on aldehyde oxidase activity.2010

    • Author(s)
      Tayama Y, Sugihara K, Sanoh S, Miyake K, Morita S, Kitamura S, Ohta S
    • Journal Title

      Drug Metab Pharmacokinet.

      Volume: 26(1) Pages: 94-101

    • NAID

      130004463166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009

    • Author(s)
      杉原数美, 等
    • Journal Title

      有害・医療廃棄物研究 21

      Pages: 23-23

    • NAID

      40017216811

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.2009

    • Author(s)
      Inoue T, Sugihara K, Ohshita H, Horie T, Kitamura S, Ohta S.
    • Journal Title

      Drug Metab.Pharmacokinet. 24

      Pages: 153-160

    • NAID

      10025723190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Current situation of drug in for mation in the kindergarten andnursery teacher : a pilot study2009

    • Author(s)
      Tayama Y, Miyake K, Kanazawa E, KanekoT, Sugihara K, Toyomi A, Morita S, Kobayashi M, Ohta S.
    • Journal Title

      YakugakuZasshi

      Volume: 129 Pages: 617-622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Prediction of human disposition toward S3Hwarfarin using chimeric mice with humanized liver2009

    • Author(s)
      Inoue, Tae ; Sugihara, Kazumi ; Ohshita, Hiroki ; Horie, Torn ; Kitamura, Shigeyuki ; Ohta, Shigeru
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 24(2) Pages: 153-160

    • NAID

      10025723190

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Prediction of humandisposition toward S-3H-warfarin usingchimeric mice with humanized liver2009

    • Author(s)
      Inoue T, Sugihara K, Ohshita H, HorieT, Kitamura S, Ohta S.
    • Journal Title

      DrugMetab Pharmacokinet

      Volume: 24 Pages: 153-160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study2009

    • Author(s)
      Tayama, Yoshitaka ; Miyake, Katsushi ; Kanazawa, Erl ; Kaneko, Tetuo ; Sugihara, Kazumi ; Toyomi, Atsushi ; Marita, Shushi ; Kobayashi, Masao ; Ohta, Shigeru
    • Journal Title

      Yakugaku Zasshi

      Volume: 129(5) Pages: 617-622

    • NAID

      130000136166

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Disruption of thyroid hormone function by environmental Pollutants2009

    • Author(s)
      Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
    • Journal Title

      Journal of Health Science 55(2)

      Pages: 147-160

    • NAID

      110007161008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
    • Journal Title

      Environmental Health Perspectives 17(8)

      Pages: 1210-1218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima Hiroyuki ; Takeuchi Shinji ; Uramaru Naoto ; Sugihara Kazumi ; Yoshida Takahiko ; Kitamura Shigeyuki
    • Journal Title

      Environmental Health Perspectives 117(8)

      Pages: 1210-1218

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Modulation of connexin 43 in rotenone-induced model of Parkinson's disease2009

    • Author(s)
      Kawasaki A.; Hayashi T.; Nakachi K.; Trosko J. E.; Sugihara K.; Kotake Y.; Ohta S.
    • Journal Title

      Neuroscience 160(1)

      Pages: 61-68

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Disruption of thyroid hormone function by environmental pollutants2009

    • Author(s)
      Kashiwagi, Keiko, Furuno, Nobuaki, Kitamura, Shigeyuki, Ohta, Shigeru, Sugihara, Kazumi, Utsumi, Kozo, Hanada, Hideki, Taniguchi Kikuyo, Suzuki, Ken-ichi, Kashiwagi, Akihiko
    • Journal Title

      Journal of Health Science 55(2)

      Pages: 147-160

    • NAID

      110007161008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009

    • Author(s)
      杉原数美, 等
    • Journal Title

      有害・医療廃棄物研究 21

      Pages: 23-23

    • NAID

      40017216811

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] 広島県内における在宅医療廃棄物の発生・回収・廃棄に関する調査2009

    • Author(s)
      杉原数美 等
    • Journal Title

      有害・医療廃棄物研究 21(in press)

    • NAID

      40017216811

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Disruption of thyroid hormone function by environmental pollutants2009

    • Author(s)
      Kashiwagi, Keiko ; Furuno, Nobuaki ; Kitamura, Shigeyuki ; Ohta, Shigeru ; Sugihara, Kazumi ; Utsumi, Kozo ; Hanada, Hideki ; Taniguchi, Kikuyo ; Suzuki, Ken-ichi ; Kashiwagi, Akihiko
    • Journal Title

      Journal of Health Science

      Volume: 55(2) Pages: 147-160

    • NAID

      110007161008

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Modulation of connexin 43 in rotenoneinduced model of Parkinson's disease2009

    • Author(s)
      Kawasaki, A.; Hayashi, T.; Nakachi, K.; Trosko, J. E.; Sugihara, K.; Kotake, Y.; Ohta, S
    • Journal Title

      Neuroscience

      Volume: 160(1) Pages: 61-68

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Modulation of connexin 43 in rotenone-induced model of Parkinson's disease.2009

    • Author(s)
      Kawasaki A, Hayashi T, Nakachi K, Trosko JE, Sugihara K, Kotake Y, Ohta S.
    • Journal Title

      Neuroscience 160

      Pages: 61-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study2009

    • Author(s)
      Tayama Yoshitaka ; Miyake Katsushi ; Kanazawa Eri ; Kaneko Tetuo ; Sugihara Kazumi ; Toyomi Atsushi ; Morita Shushi ; Kobayashi Masao ; Ohta Shigeru
    • Journal Title

      Yakugaku Zasshi 129(5)

      Pages: 617-622

    • NAID

      130000136166

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima, Hiroyuki ; Takeuchi, Shinji ; Uramaru, Naoto ; Sugihara, Kazumi ; Yoshida, Takahiko ; Kitamura, Shigeyuki
    • Journal Title

      Environmental Health Perspectives

      Volume: 117(8) Pages: 1210-1218

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Nuclear hormone receptor activity of polybrominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009

    • Author(s)
      Kojima, Hiroyuki, Takeuchi, Shinji, Uramaru, Naoto, Sugihara, Kazumi, Yoshida, Takahiko, Kitamura, Shigeyuki
    • Journal Title

      Environmental Health Perspectives 17(8)

      Pages: 1210-1218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Disruption of thyroid hormone function by environmental pollutants2009

    • Author(s)
      Kashiwagi Keiko ; Furuno Nobuaki ; Kitamura Shigeyuki ; Ohta Shigeru ; Sugihara Kazumi ; Utsumi Kozo ; Hanada Hideki ; Taniguchi Kikuyo ; Suzuki Ken-ichi ; Kashiwagi Akihiko
    • Journal Title

      Journal of Health Science 55(2)

      Pages: 147-160

    • NAID

      110007161008

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Current situation of drug information in the kindergarten and nursery teacher : a pilot study.2009

    • Author(s)
      Tayama Y, Miyake K, Kanazawa E, Kaneko T, Sugihara K, Toyomi A, Morita S, Kobayashi M, Ohta S.
    • Journal Title

      Yakugaku Zasshi. 129

      Pages: 617-622

    • NAID

      130000136166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver2009

    • Author(s)
      Inoue Tae ; Sugihara Kazumi ; Ohshita Hiroki ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
    • Journal Title

      Drug Metabolism and Pharmacokinetics 24(2)

      Pages: 153-160

    • NAID

      10025723190

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver2008

    • Author(s)
      Inoue Tae ; Nitta Kayoko ; Sugihara Kazumi ; Horie Toru ; Kitamura Shigeyuki ; Ohta Shigeru
    • Journal Title

      Drug Metabolism and Disposition 36(12)

      Pages: 2429-2433

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008

    • Author(s)
      Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
    • Journal Title

      J. Health Sci. 54

      Pages: 343-355

    • NAID

      110006835680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Journal Article] Metabolic activation of proestrogens in the environment by cytochrome P450 system2008

    • Author(s)
      Kitamura Shigeyuki ; Sugihara Kazumi ; Sanoh Seigo ; Fujimoto Nariaki ; Ohta Shigeru
    • Journal Title

      Journal of Health Science 54(4)

      Pages: 343-355

    • NAID

      110006835680

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2008

    • Author(s)
      Sugihara Kazumi ; Okayama Takashige ; Kitamura Shigeyuki ; Yamashita Keisuke ; Yasuda Mineo ; Miyairi Shinichi ; Minobe Yasushi ; Ohta Shigeru
    • Journal Title

      Archives of Toxicology 82(1)

      Pages: 5-11

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo.2008

    • Author(s)
      Sugihara K, Okayama T, Kitamura S, Yamashita K, Yasuda M, Miyairi S, Minobe Y, Ohta S.
    • Journal Title

      Arch.Toxicol. 82

      Pages: 5-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Study on the pharmaceuticals in hospital sewage and their toxicities in the aquatic environment2008

    • Author(s)
      Sugihara Kazumi
    • Journal Title

      Yakugaku Kenkyu no Shinpo, (2009) 25

      Pages: 99-105

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver2008

    • Author(s)
      Kitamura Shigeyuki ; Nitta Kayoko ; Tayama Yoshitaka ; Tanoue Chiaki ; Sugihara Kazumi ; Inoue Tae ; Horie Toru ; Ohta Shigeru
    • Journal Title

      Drug Metabolism and Disposition 36(7)

      Pages: 1202-1205

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.2008

    • Author(s)
      Inoue T, Nitta K, Sugihara K, Horie T, Kitamura S, Ohta S.
    • Journal Title

      Drug Metab.Dispos. 36

      Pages: 2429-2433

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Aldehyde oxidase-catalyzed metabolism ofN1-methylnicotinamide in vivo and in vitroin chimeric mice with humanized liver2008

    • Author(s)
      Kitamura S, Nitta K, Tayama Y, TanoueC, Sugihara K, Inoue T, Horie T, Ohta S.
    • Journal Title

      Drug Metab Dispos

      Volume: 36 Pages: 1202-1205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers2008

    • Author(s)
      Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
    • Journal Title

      J. Health Sci. 54

      Pages: 607-614

    • NAID

      110006935591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Journal Article] Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver.2008

    • Author(s)
      Kitamura S, Nitta K, Tayama Y, Tanoue C, Sugihara K, Inoue T, Horie T, Ohta S.
    • Journal Title

      Drug.Metab.Dispos. 36

      Pages: 1202-1205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390040
  • [Journal Article] Affinity for thyroid hormone and estrogen receptors of hydroxylated polybrominated diphenyl ethers2008

    • Author(s)
      Kitamura Shigeyuki ; Shinohara Seiji ; Iwase Eri ; Sugihara Kazumi ; Uramaru Naoto ; Shigematsu Hidenari ; Fujimoto Nariaki ; Ohta Shigeru
    • Journal Title

      Journal of Health Science 54(5)

      Pages: 607-614

    • NAID

      110006935591

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] Metabolicactivation of proestrogens in theenvironment by cytochrome P450 system2008

    • Author(s)
      Kitamura, S., Sugihara K., Sanoh, S., Fujimoto, N., Ohta, S.
    • Journal Title

      J. Health Science

      Volume: 54 Pages: 343-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Journal Article] Study on the pharmaceuticals in hospital sewage and their toxicities in the aquatic environment2008

    • Author(s)
      Sugihara, Kazumi
    • Journal Title

      Yakugaku Kenkyu no Shinpo

      Volume: 25 Pages: 99-105

    • Data Source
      KAKENHI-PROJECT-21406005
  • [Journal Article] Effects of endocrine disrupting chemicals on amphibian metamorphosis and mitochondrial membrane permeability transition2008

    • Author(s)
      Kashiwagi Akihiko ; Utsumi Kozo ; Kashiwagi Keiko ; Ohta Shigeru ; Sugihara Kazumi ; Hanada Hideki ; Kitamura Shigeyuki
    • Journal Title

      Journal of Health Science 54(3)

      Pages: 273-280

    • NAID

      110006684374

    • Data Source
      KAKENHI-PROJECT-20590122
  • [Journal Article] CYP2C9-catalyzedmetabolism of S-warfarin to 7-hydroxywarfarinin vivo and in vitro in chimericmice with humanized liver2008

    • Author(s)
      Inoue T, Nitta K, Sugihara K, Horie T, Kitamura S, Ohta S.
    • Journal Title

      Drug MetabDispos

      Volume: 36 Pages: 2429-2433

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406005
  • [Journal Article] Affinity for ThyroidHormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers.2008

    • Author(s)
      Kitamura, S., Shinohara, S., Iwase, S., Sugihara, K., Uramaru, N., Shigematsu, N., Fujimoto, N., Ohta, S.
    • Journal Title

      J. Health Science

      Volume: 54 Pages: 607-614

    • NAID

      110006935591

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007

    • Author(s)
      Sugihara et al.
    • Journal Title

      archives of Toxicology (In press)

    • Data Source
      KAKENHI-PROJECT-18590118
  • [Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007

    • Author(s)
      Sugihara, et. al.
    • Journal Title

      Archives of Toxicology 82

      Pages: 5-11

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Journal Article] The in vitro metabolism of a pyrethroid insecticide, permethrin, and its hydrolyzed oroducts in rats2007

    • Author(s)
      Y., Nakamura, K., Sugihara, T., Sone, M., Isobe, S., Ohta, S., Kitamura
    • Journal Title

      Toxicology 235

      Pages: 176-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Journal Article] Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo2007

    • Author(s)
      K., Sugihara, T., Okayama, S., Kitamura, K., Yamashita, M., Yasuda, S., Miyairi, Y., Minobe, S., Ohta
    • Journal Title

      Archives of Toxicology 82

      Pages: 5-11

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Journal Article] Effects of stilbene and related compounds on reproductive organs in B6C3F1/Crj mouse H. Fujita, Y. Okimura, T. Utsumi, S. Kitamura, H. Kuroki, T. Otsuki, J. Sasaki, A. Kashiwag2006

    • Author(s)
      S., Sanoh, S., Kitamura, R., Kohta, K., Sugihara, S., Ohta, H., Watanabe
    • Journal Title

      Journal of Health Sciences 52(5)

      Pages: 613-622

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of Nl-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006

    • Author(s)
      Sugihara, Kazumi,. et al.
    • Journal Title

      Drug Metabolism and Disposition 34(2)

      Pages: 208-212

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590102
  • [Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006

    • Author(s)
      Sugihara, Kazumi, etal.
    • Journal Title

      Drug Metabolism and Disposition 34(2)

      Pages: 208-212

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590102
  • [Journal Article] Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.2006

    • Author(s)
      Sugihara, Kazumi, et al.
    • Journal Title

      Drug Metabolism and Disposition 34(2),

      Pages: 208-212

    • Data Source
      KAKENHI-PROJECT-17590102
  • [Journal Article] Comparative study of the endocrine-disrupting activity of bisphenol A and 19 related compounds2005

    • Author(s)
      S.Kitamura, T.Suzuki, S.Sanoh, R.Kohta, N.Jinno, K.Sugiharaら
    • Journal Title

      Toxicological Sciences 84

      Pages: 249-259

    • Data Source
      KAKENHI-PROJECT-16590092
  • [Journal Article] Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreen2005

    • Author(s)
      T.Suzuki, S.Kitamura, R.Khota, K.Sugihara, N.Fujimoto, S.Ohta
    • Journal Title

      Toxicology and Applied Pharmacology 203

      Pages: 9-17

    • Data Source
      KAKENHI-PROJECT-16590092
  • [Journal Article] Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture2005

    • Author(s)
      S.Kitamura, N.Jinno, T.Suzuki, K.Sugihara, S.Ohtaら
    • Journal Title

      Toxicology 208

      Pages: 377-387

    • Data Source
      KAKENHI-PROJECT-16590092
  • [Journal Article] Aryl hydrocarbon receptor-mediated induction of microsomal drug-metabolizing enzyme activity by indirubin and indigo2004

    • Author(s)
      K.Sugihara, S.Kitamura, T.Yamada, T.Okayama, S.Ohta
    • Journal Title

      Biochemical and Biophysical Research Communication 318

      Pages: 571-578

    • Data Source
      KAKENHI-PROJECT-16590092
  • [Presentation] マウス、ヒトに発現するAO タンパク質の分解系の同定2019

    • Author(s)
      加藤 真帆, 佐能 正剛, 高岡 尚輝, 大月 佑也, 杉原 数美, Mineko TERAO, Enrico GARATTINI, 太田 茂, 古武 弥一郎
    • Organizer
      日本薬学会139年会 千葉幕張メッセ 2019年3月20-22日
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] モリブデン含有薬物代謝酵素における概日リズムの検討2019

    • Author(s)
      田山 剛崇、前田 志津子、岡村 友理香、喜多 智生、杉原 数美、三宅 勝志
    • Organizer
      日本薬学会 第140年会
    • Data Source
      KAKENHI-PROJECT-19K07182
  • [Presentation] 離乳期におけるラット肝CYPおよびaldehyde oxidaseの変動2019

    • Author(s)
      杉原 数美, 村川 晃大, 荒井 美幸, 田山 剛崇, 清水 良, 北村 繁幸, 太田 茂
    • Organizer
      日本薬学会139年会 千葉幕張メッセ 2019年3月20-22日
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Aldehyde oxidase およびCYP2A6 がnicotine 代謝に及ぼす影響2019

    • Author(s)
      田山 剛崇, 西村 さとみ, 杉原 数美, 北村 繁幸, 佐和 章弘, 三宅 勝志
    • Organizer
      日本薬学会139年会 千葉幕張メッセ 2019年3月20-22日
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Aldehyde oxidase およびCYP2A6 がnicotine 代謝に及ぼす影響2019

    • Author(s)
      田山 剛崇, 西村 さとみ, 杉原 数美, 北村 繁幸, 佐和 章弘, 三宅 勝志
    • Organizer
      日本薬学会139年会 千葉幕張メッセ 2019年3月20-22日
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] 離乳期におけるラット肝CYPおよびaldehyde oxidaseの変動2019

    • Author(s)
      杉原 数美, 村川 晃大, 荒井 美幸, 田山 剛崇, 清水 良, 北村 繁幸, 太田 茂
    • Organizer
      日本薬学会139年会 千葉幕張メッセ 2019年3月20-22日
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] Aldehyde oxidase低活性系統マウスでのAOX分子種の発現調節2019

    • Author(s)
      津川 成樹、東 沙也香、吉村 彰恵、清水 良、佐能 正剛,古武 弥一郎、北村 繁幸、太田 茂,杉原 数美
    • Organizer
      第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] 薬物代謝酵素aldehyde oxidaseにおける概日リズムの検討2019

    • Author(s)
      田山剛崇, 喜多 智生, 西村 さとみ, 前田 志津子, 杉原 数美, 佐和 章弘, 三宅 勝志
    • Organizer
      第29回 日本医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-19K07182
  • [Presentation] リン系難燃剤のラット肝および小腸カルボキシルエステラーゼに対する阻害効果2018

    • Author(s)
      津越 幸枝,渡部 容子,杉原 数美,北村 繁幸
    • Organizer
      フォーラム2018衛生薬学・環境トキシコロギー アルカス佐世保 2018年9月10-11日
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Assessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018

    • Author(s)
      Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini, Shigeru Ohta, Yaichiro Kotake
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Sex differences of aldehyde oxidases in mouse liverAssessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches2018

    • Author(s)
      Kazumi Sugihara, Yoshitaka Tayama, Seigo Sanoh, Shigeyuki Kitamura, Shigeru Ohta
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Assessment of inhibitory effects of drugs on mouse and human aldehyde oxidases through in silico, in vitro, and in vivo approaches.2018

    • Author(s)
      Naoki Takaoka, Seigo Sanoh, Katsuhiro Okuda, Go Sugahara, Ami Yanagi, Yuji Ishida, Chise Tateno, Yoshitaka Tayama, Kazumi Sugihara, Shigeyuki Kitamura, Mami Kurosaki, Mineko Terao, Enrico Garattini, Shigeru Ohta, Yaichiro Kotake
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] Sex differences of aldehyde oxidases in mouse liver2018

    • Author(s)
      Kazumi Sugihara, Yoshitaka Tayama, Seigo Sanoh, Shigeyuki Kitamura, Shigeru Ohta
    • Organizer
      2018 International Meeting on 22nd MDO and 33rd JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] 臭素化難燃剤PBDE類によるAhRの活性化を介したUGT遺伝子発現誘導機構.内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング2017

    • Author(s)
      清水 良,浦丸直人,渡部容子, 太田 茂, 北村繁幸, 杉原数美
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] Strain and sex differences of aldehyde oxidase isozymes in mouse liver2017

    • Author(s)
      杉原数美、平本耕一、田坂真希、田山剛崇、佐能正剛、太田 茂、北村繁幸
    • Organizer
      日本薬物動態学会 第32回年会
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] 医薬品類による環境汚染と環境因子による毒性変動2017

    • Author(s)
      杉原数美
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] 塩素消毒処理による医薬品および生活関連化学物質の毒性変動調査2017

    • Author(s)
      國澤和憲、岡田達司、堂脇美緒、井上沙也香、清水 良、北村繁幸、太田 茂、杉原数美
    • Organizer
      フォーラム2017:衛生薬学・環境トキシコロジー
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] 薬物代謝酵素アルデヒドオキシダーゼのマウスにおける性差と系統差2017

    • Author(s)
      岸沙也香、村川晃大、平本耕一、清水 良、佐能正剛、太田 茂、北村繁幸、杉原数美
    • Organizer
      第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] 薬物代謝酵素アルデヒドオキシダーゼのマウスにおける性差と系統差2017

    • Author(s)
      岸沙也香、村川晃大、平本耕一、清水 良、佐能正剛、太田 茂、北村繁幸、杉原数美
    • Organizer
      第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] マウス肝アルデヒドオキシダーゼの性特異的発現機序の検討2017

    • Author(s)
      内藤祐子,田坂真希,富吉博也,濱﨑千尋,清水 良,佐能正剛,太田 茂,北村繁幸、杉原数美
    • Organizer
      第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] マウス肝アルデヒド酸化酵素分子種の系統差と性差2017

    • Author(s)
      杉原数美, 平本耕一, 田坂真希, 田山剛崇, 佐能正剛, 太田 茂, 北村繁幸
    • Organizer
      日本薬物動態学会第32回年会
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] マウス肝アルデヒドオキシダーゼの性特異的発現機序の検討2017

    • Author(s)
      内藤祐子、田坂真希、富吉博也、濱﨑千尋、清水 良、佐能 正剛、太田 茂、北村繁幸、杉原 数美
    • Organizer
      第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-17K08401
  • [Presentation] リン系難燃剤のラットカルボキシルエステラーゼ活性に対する阻害効果2017

    • Author(s)
      津越幸枝,渡部容子,杉原数美,北村繁幸
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K00559
  • [Presentation] ロキソプロフェンナトリウム水和物細粒の飛散性に影響を与える因子の検討2016

    • Author(s)
      土井えりか、手嶋茂貴、杉原数美、田山剛崇、三宅勝志
    • Organizer
      第26回 日本医療薬学会年会
    • Place of Presentation
      京都
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-16K08428
  • [Presentation] ロキソプロフェンナトリウム水和物細粒の飛散性に影響を与える因子の検討2016

    • Author(s)
      前田 志津子, 土井 えりか, 手嶋 茂貴, 杉原 数美, 田山 剛崇, 三宅 勝志
    • Organizer
      第26回日本医療薬学会年会
    • Place of Presentation
      国立京都国際会館(京都市左京区)
    • Year and Date
      2016-09-17
    • Data Source
      KAKENHI-PROJECT-26460247
  • [Presentation] ラット肝、小腸及び膵臓ミクロソームのフタル酸エステルに対する加水分解活性の基質特異性2016

    • Author(s)
      森口恭子,渡部容子,杉原数美,北村繁幸
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] タンニン酸アルブミンの製品間比較~帯電量調査~2016

    • Author(s)
      前田 志津子, 手嶋 茂貴, 田山 剛崇, 安原 昌子, 寺重 隆視, 杉原 数美,佐和 章弘, 三宅 勝志
    • Organizer
      日本薬学会第 136年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26460247
  • [Presentation] Allopurinol代謝に及ぼす投与量の影響2016

    • Author(s)
      田山剛崇,杉原数美,三宅勝志,北村繁幸,太田 茂
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 臭素化難燃剤のPBDEおよびその代謝物による肝UGT遺伝子発現への影響2016

    • Author(s)
      清水 良,浦丸直人,渡部容子,太田 茂,北村繁幸,杉原数美
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 患者の残薬管理および廃棄活動に関する調査2016

    • Author(s)
      杉原 数美、前田 志津子、田山 剛崇、西村 和之、太田 茂
    • Organizer
      日本薬学会第 136年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26460247
  • [Presentation] リン系難燃剤のラット肝カルボキシルエステラーゼ活性に対する阻害効果2015

    • Author(s)
      渡部容子,井上智賀,谷川悠華,浦丸直人,杉原数美,小島弘幸,北村繁幸
    • Organizer
      フォーラム2015 衛生薬学・環境トキシコロジー
    • Place of Presentation
      神戸
    • Year and Date
      2015-09-17
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 先発医薬品と後発医薬品の比較:ロキソプロフェンナトリウム水和物細粒の飛散粉じん量調査2015

    • Author(s)
      前田 志津子、土井 えりか、杉原 数美、田山 剛崇、塚本 豊久
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザイン・クリエイティブセンター神戸(神戸市中央区)
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-26460247
  • [Presentation] Allopurinol代謝におけるaldehyde oxidase活性の寄与に関する検討2014

    • Author(s)
      田山剛崇,杉原数美,三宅勝志,北村繁幸,太田 茂
    • Organizer
      日本薬学会 第134年回
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25460235
  • [Presentation] 医薬品類による水環境汚染と生態毒性2013

    • Author(s)
      杉原数美ら
    • Organizer
      フォーラム2013 衛生薬学・環境トキシコロジー
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 新生児期甲状腺ホルモン撹乱の影響-成体期肝遺伝子発現変化-2013

    • Author(s)
      中村直樹, 佐能正剛, 松原加奈, 杉原数美, 浦丸直樹, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田 茂
    • Organizer
      フォーラム2013衛生薬学・環境トキシコロジー
    • Place of Presentation
      九州大学(福岡)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 新生児期甲状腺ホルモン撹乱の影響-成体期肝遺伝子発現変化-2013

    • Author(s)
      中村直樹、佐能正剛、松原加奈、杉原数美、浦丸直人、北村繁幸、宮川信一、井口泰泉、藤本成明、太田茂
    • Organizer
      フォーラム2013衛生薬学・環境トキシコロジー
    • Place of Presentation
      九州大学(福岡)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] Allopurinol 代謝におけるxanthine oxidase および aldehyde oxidaseの関与2013

    • Author(s)
      田山武崇, 杉原数美, 三宅勝志, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ヒト肝細胞移植キメラマウスを用いたアロメトリックスケーリングによるヒト体内動態予測性評価2013

    • Author(s)
      藤本真美、佐能正剛、成富洋一、佐藤公也、河村章生、堀口彩、杉原数美、北村繁幸、堀江透、立野知世、太田茂
    • Organizer
      日本薬物動態学会 第28回年会
    • Place of Presentation
      タワーホール船堀(東京)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 穀物によるマウス肝薬物代謝酵素の変動2013

    • Author(s)
      清水良, 山口雅史, 浦丸直人, 黒木広明, 北村繁幸, 太田茂, 杉原数美
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ヒト肝細胞移植キメラマウスを用いたアロメトリックスケーリングによるヒト体内動態予測性評価2013

    • Author(s)
      藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 北村繁幸, 堀江透, 立野知世, 太田 茂
    • Organizer
      日本薬物動態学会第28回年会
    • Place of Presentation
      タワーホール船堀(東京)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] ヒト・マウスにおけるアルデヒドオキシダーゼの代謝活性と基質特異性の比較2013

    • Author(s)
      小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山武崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] Predictability of plasma concentration-time profiles in humans using chimeric mice with humanized liver2013

    • Author(s)
      Sanoh S, Fujimoto N, Naritomi Y, Sato K, Kawamura A, Horiguchi A, Sugihara K, Kitamura S, Horie T, Tateno C, Ohta S
    • Organizer
      10th International ISSX meeting
    • Place of Presentation
      Toronto(Canada)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] Sex differences of aldehyde oxidases in mouse liver2013

    • Author(s)
      Kazumi Sugihara et al.
    • Organizer
      日本薬物動態学会第28回年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト体内動態予測の検証2013

    • Author(s)
      藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] Predictability of plasma concentration-time profiles in humans using chimeric mice with humanized liver2013

    • Author(s)
      Sanoh S, Fujimoto M, Naritomi Y, Sato K, Kawamura A, Horiguchi A, Sugihara K, Kitamura S, Horie T, Tateno C, Ohta S.
    • Organizer
      10th International ISSX meeting
    • Place of Presentation
      Toronto (Canada)
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] PCB および PBDE の水酸化代謝物のヨードチロシン脱ヨウ素化酵素阻害作用2013

    • Author(s)
      山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] アセトアミノフェンおよびスリンダクの水環境中における光分解物の同定2013

    • Author(s)
      川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第133 年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] Effect of UV irradiation on the ecotoxicity of pharmaceuticals in aquatic environment2012

    • Author(s)
      Kawabata K., Ogawa Y., Sugihara K., Sanoh S., Kitamura S., Ohta S.
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 水環境中医薬類の太陽光・紫外線による毒性変動2012

    • Author(s)
      川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      第39回日本毒性学会学術年会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 食餌がマウス肝薬物代謝酵素に及ぼす影響の1H-NMR メタボローム解析2012

    • Author(s)
      杉原数美, 佐光華佳, 田上加苗, 三間昭平, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ヒト肝細胞移植マウスを用いたイブプロフェンの代謝、血中動態の予測2012

    • Author(s)
      佐能正剛、堀口彩、杉原数美、浦丸直人、立野知世、堀江透、北村繁幸、太田茂
    • Organizer
      日本薬学会132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] Prediction of human pharmacokinetics by allometric scaling using chimeric mice with humanized liver2012

    • Author(s)
      Sanoh S., Naritomi Y., Sato K., Kawamura A., Horiguchi A., Sugihara K., Tateno C., Horie T., Kitamura S., Ohta S
    • Organizer
      19th International Symposium on Microsomes and Drug Oxidations 12th European Regional ISSX Meeting
    • Place of Presentation
      Noordwijk aan Zee, Netherlands
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 環境化学物質の転写活性化を介した甲状腺ホルモン撹乱作用2012

    • Author(s)
      松原加奈, 佐能正剛, 藤本成明, 杉原数美, 北村繁幸, 太田 茂
    • Organizer
      日本薬学会132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-31
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] ヒト肝細胞移植マウスを用いたイブプロフェンの代謝, 血中動態の予測2012

    • Author(s)
      佐能正剛, 堀口 彩, 杉原数美, 浦丸直人, 立野知世, 堀江 透, 北村繁幸, 太田 茂
    • Organizer
      日本薬学会132年会
    • Place of Presentation
      札幌
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 食餌がマウス肝薬物代謝酵素に及ぼす影響の1H-NMRメタボローム解析,2012

    • Author(s)
      杉原数美ら
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ヒト・マウス・ヒト肝キメラマウスにおけるアルデヒドオキシダーゼの酵素活性の比較2012

    • Author(s)
      小原裕月, 佐能正剛, 杉原数美, 岸野貴大, 田山剛崇, 浦丸直人, 立野知世, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 釜山市(大韓民国)の市街地を流域とする温泉川での医薬品汚染調査2012

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
    • Organizer
      第46回日本水環境学会年会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 62 種生薬エキスの Ah レセプター結合活性の評価2012

    • Author(s)
      杉原数美, 渡部容子, 北村繁幸, 原田亜紀子, 太田茂, 山路誠一
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 62種生薬エキスのAhレセプター結合活性の評価2012

    • Author(s)
      杉原数美ら
    • Organizer
      第29回和漢医薬学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 環境科学物質による甲状腺ホルモン撹乱作用の in vitro および in vivo 評価2012

    • Author(s)
      松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直人, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田茂
    • Organizer
      フォーラム 2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ラット肝細胞スフェロイドにおける蛍光プローブを用いたアセトアミノフェン、ジクロフェナクによる肝毒性評価2012

    • Author(s)
      山頭征岳, 佐能正剛, 杉原数美, 江尻洋子, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ヒト肝細胞移植キメラマウスにおけるアロメトリックスケーリングを用いたヒト血中動態予測性の検証2012

    • Author(s)
      藤本真美, 佐能正剛, 成富洋一, 佐藤公也, 河村章生, 堀口彩, 杉原数美, 立野知世, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第27回年会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 環境化学物質による甲状腺ホルモン撹乱作用のin vitro、in vivo評価2012

    • Author(s)
      松原加奈、中村直樹、佐能正剛、杉原数美、浦丸直人、北村繁幸、宮川信一、井口泰泉、藤本成明、太田茂
    • Organizer
      フォーラム2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 環境化学物質による甲状腺ホルモン撹乱作用のin vitro, in vivo 評価2012

    • Author(s)
      松原加奈, 中村直樹, 佐能正剛, 杉原数美, 浦丸直樹, 北村繁幸, 宮川信一, 井口泰泉, 藤本成明, 太田 茂
    • Organizer
      フォーラム2012衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] アセトアミノフェンの水環境中における光分解と光毒性2012

    • Author(s)
      川畑公平, 尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム 2012 衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011

    • Author(s)
      杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
    • Organizer
      第45回日本水環境学会年会
    • Place of Presentation
      札幌市(北海道大学)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 佐能正剛、北村繁幸、太田茂
    • Organizer
      フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 釜山市街を流域とする中規模河川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Moon Jeon-Ok, 太田茂
    • Organizer
      フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美, ら
    • Organizer
      第131回日本薬学会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 環境化学物質の甲状腺ホルモン攪乱作用in vitro評価2011

    • Author(s)
      松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011

    • Author(s)
      川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011

    • Author(s)
      川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美、川畑公平、Mon Jyoun、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] Prediction of PK parameters of human using human chimeric mice2011

    • Author(s)
      Sanoh S, Horiguchi A, Sugihara K, Tateno C, Horie T, Kitamura S, Ohta S
    • Organizer
      17^<th> International Society for the Study of Xenobiotics North American Meeting
    • Place of Presentation
      Atlanta, Georgia, USA
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] ヒト肝キメラマウスを用いたイブプロフェンのキラル変換2011

    • Author(s)
      堀口 彩, 佐能正剛, 杉原数美, 立野知世, 堀江 透, 北村繁幸, 太田 茂
    • Organizer
      第26回日本薬物動態学会
    • Place of Presentation
      広島
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] Prediction of PK parameters of human using human chimeric mice2011

    • Author(s)
      Sanoh S, Horiguchi A, Sugihara K, Tateno C, Horie T, Kitamura S, Ohta S
    • Organizer
      17th International Society for the Study of Xenobiotics North American Meeting
    • Place of Presentation
      Atlanta, Georgia, USA
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 薬物代謝酵素の成長に伴う発達と食餌の影響.Developmental changes of drug-metabolizing enzymes and effect of dietary constituents in rats and mice2011

    • Author(s)
      杉原数美, ら
    • Organizer
      第26回日本薬物動態学会年会(シンポジュウム)
    • Place of Presentation
      広島(招待講演)
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 大韓民国釜山市温泉川の医薬品汚染調査2011

    • Author(s)
      杉原数美, 他
    • Organizer
      第131回日本薬学会
    • Place of Presentation
      静岡市
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011

    • Author(s)
      杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
    • Organizer
      第45回日本水環境学会年会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011

    • Author(s)
      内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
    • Organizer
      フォーラム2011 :衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] ヒトおよびラット肝キメラマウスを用いた医薬品の代謝プロファイルの予測2011

    • Author(s)
      佐能正剛, 堀口 彩, 杉原数美, 立野知世, 堀江 透, 北村繁幸, 太田 茂
    • Organizer
      第38回日本トキシコロジー学会学術年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-07-11
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] ポテンシャルマップを用いた生活排水流入河川の医薬品汚染濃度予測2011

    • Author(s)
      杉原数美、尾川雄一、川畑公平、佐能正剛、北村繁幸、西嶋渉、太田茂
    • Organizer
      第45回日本水環境学会年会
    • Place of Presentation
      札幌市(北海道大学)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 医薬品等の特定汚染源物質による河川汚染濃度予測マップツールの作成2011

    • Author(s)
      内田博久, 川畑公平, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂, 杉原数美
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 新生仔期ラットへの甲状腺ホルモン様物質曝露による影響評価2011

    • Author(s)
      松原加奈, 佐能正剛, 藤本成明, 杉原数美, 北村繁幸, 太田 茂
    • Organizer
      フォーラム2011衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-28
    • Data Source
      KAKENHI-PROJECT-23390030
  • [Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2011

    • Author(s)
      川畑公平、杉原数美、太田茂
    • Organizer
      フォーラム2011・衛生薬学・環境トキシコロジーシンポジウム
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 紫外線照射による水環境中医薬品類の分解および水生生物への毒性変動調査2011

    • Author(s)
      川畑公平、杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(グランシップ静岡など)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境化学物質の甲状腺ホルモン撹乱作用in vitro評価2011

    • Author(s)
      松原加奈, 佐能正剛, 藤本成明, 浦丸直人, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡市(要旨発表)
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010

    • Author(s)
      秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市(沖縄コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一, 杉原数圭, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質のproteindisulfide isomerase(PDI)への結合による内分泌系に対する影響2010

    • Author(s)
      佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生薬学・環境トキシコロジー
    • Place of Presentation
      東京
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市(沖縄コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010

    • Author(s)
      秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美1, 尾川雄一, 佐光華佳, M.Yuwano, A.H.Syahrani, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010

    • Author(s)
      佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
    • Organizer
      第130回日本薬学会年会
    • Place of Presentation
      岡山市
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈,佐能正剛,岩瀬恵理,藤本成明,浦丸直人,杉原数美,加藤善久,北村繁幸,太田茂
    • Organizer
      フォーラム2010衛生環境トキわシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美, 尾川雄一, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一、杉原数美、川畑公平、佐光華佳、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査,フォーラム2010衛生環境トキシコロジー2010

    • Author(s)
      秋吉里絵, 古道律子, 宗重美恵子, 杉原数美, 尾川雄一, 川畑公平, 佐能正剛, 北寸繁太田
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京都(星薬科大学)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境中における甲状腺ホルモン撹乱物質のスクリーニング2010

    • Author(s)
      佐能正剛, 岩瀬恵理, 松原加奈, 杉原数美, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
    • Organizer
      130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010

    • Author(s)
      松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      環境ホルモン学会第13回研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 生活排水流入河川での医薬品による水汚染調査2010

    • Author(s)
      杉原数美、尾川雄一、川畑公平、佐光華佳、佐能正剛、太田茂、西嶋渉、北村繁幸
    • Organizer
      第44回日本水環境学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質のProtein Disulfide Isomerase(PDI)への結合による内分泌系に対する影響2010

    • Author(s)
      佐能正剛, 松原加奈, 岩瀬恵理, 今岡進, 岡田和嗣, 浦丸直人, 藤本成明, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      衛生薬学・環境トキシコロジーフォーラム2010
    • Place of Presentation
      東京都
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 生活排水流入河川での医薬品による水汚染調査2010

    • Author(s)
      杉原数美, 尾川雄一, 川畑公平, 佐光華佳, 佐能正剛, 太田茂, 西嶋渉, 北村繁幸
    • Organizer
      第44回日本水環境学会年会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美、尾川雄一、佐能正剛、北村繁幸、太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] ,広島県内保険薬局を対象とした医薬品廃棄に関するパイロット調査2010

    • Author(s)
      杉原数美、尾川雄一、佐能正剛、北村繁幸,太田茂
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 下水道未整備地域河川での医薬品汚染ポテンシャルマップを用いた汚染予測と流域住民の環境保全意識調査2010

    • Author(s)
      秋吉里絵,古道律子,宗重美恵子,杉原数美,尾川雄一,川畑公平,佐能正剛,北村繁幸,太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市(福富道の駅)
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] インドネシア・スラバヤ川の医薬品汚染調査-アイルランガ大学との共同調査2010

    • Author(s)
      杉原数美, 他
    • Organizer
      フォーラム2010:衛生薬学・環境トキシコロギー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22510071
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, Yuwano, A. H. Syahrani, M.佐能正剛, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生環境トキシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市(米子コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      衛生薬学・環境トキシコロジーフォーラム2010
    • Place of Presentation
      東京都
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 黒瀬川の水質汚染調査報告2010

    • Author(s)
      杉原数美
    • Organizer
      平成22年度東広島市公衆衛生協議会総会
    • Place of Presentation
      東広島市(福富道の駅)
    • Year and Date
      2010-04-22
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 環境化学物質甲状腺ホルモン作用の高感度レポータージーンアッセイ2010

    • Author(s)
      松原加奈, 藤本成明, 佐能正剛, 杉原数美, 北村繁幸, 太田茂
    • Organizer
      環境ホルモン学会第13回研究発表会
    • Place of Presentation
      東京都
    • Year and Date
      2010-12-16
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 水環境中医薬品の紫外線による分解物生成と水棲生物毒性変動2010

    • Author(s)
      尾川雄一,杉原数美,川畑公平,佐光華佳,佐能正剛,北村繁幸,太田茂
    • Organizer
      日本トキシコロジー学会
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入モデル河川における医薬品環境負荷予測2010

    • Author(s)
      尾川雄一, 杉原数美, 川畑公平, 佐光華佳, 佐能正剛, 北村繁幸, 太田茂
    • Organizer
      日本薬学会 第130年会
    • Place of Presentation
      岡山市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] インドネシア・スラバヤ市スラバヤ川の医薬品汚染調査~アイルランガ大学との共同調査~2010

    • Author(s)
      杉原数美,尾川雄一,佐光華佳,M.Yuwano, A.H.Syahrani,佐能正剛,北村繁幸,太田茂
    • Organizer
      フォーラム2010衛生環境トキわシコロジー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質による甲状腺ホルモン応答の高感度評価2010

    • Author(s)
      松原加奈, 佐能正剛, 岩瀬恵理, 藤本成明, 浦丸直人, 杉原数美, 加藤善久, 北村繁幸, 太田茂
    • Organizer
      フォーラム2010衛生薬学・環境トキシコロジー
    • Place of Presentation
      東京
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] 生活排水流入河川の生活関連物質汚染と流域住民への環境保全意識調査2010

    • Author(s)
      秋吉里絵、古道律子、宗重美恵子、尾川雄一、川畑公平、佐能正剛、太田茂、杉原数美
    • Organizer
      第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      米子市(米子コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川 黒瀬川での調査-2009

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009

    • Author(s)
      尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009

    • Author(s)
      佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
    • Organizer
      環境ホルモン学会第12回研究発表会
    • Place of Presentation
      東京
    • Year and Date
      2009-12-07
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009

    • Author(s)
      杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 臭素化難燃剤PBDEの甲状腺ホルモン受容体結合活性の代謝による変動2009

    • Author(s)
      岩瀬恵理, 小島弘幸, 杉原数美, 浦丸直人, 藤本成明, 黒木広明, 北村繁幸, 太田茂
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] ヒト肝キメラマウスを用いたヒト薬物代謝・動態予測2009

    • Author(s)
      杉原数美, 井上多恵, 田上千秋, 堀口彩, 佐能正剛, 立野知世, 堀江透, 北村繁幸, 太田茂
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009

    • Author(s)
      Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
    • Organizer
      DIOXIN2009
    • Place of Presentation
      北京市、中華人民共和国
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップーモデル河川黒瀬川での調査一2009

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川 黒瀬川での調査-2009

    • Author(s)
      杉原数美, 尾川雄一, 佐光華佳, 佐能正剛, 清水良, 北村繁幸, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 環境化学物質の甲状腺ホルモン受容体結合活性とその代謝変動2009

    • Author(s)
      佐能正剛, 岩瀬恵理, 杉原数美, 加藤善久, 浦丸直人, 藤本成明, 北村繁幸, 太田茂
    • Organizer
      環境ホルモン学会第12回研究発表会
    • Place of Presentation
      東京都
    • Year and Date
      2009-12-07
    • Data Source
      KAKENHI-PROJECT-20510065
  • [Presentation] HYDROXYLATED POLYBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009

    • Author(s)
      Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N and Ohta S
    • Organizer
      DIOXIN2009
    • Place of Presentation
      北京市、中華人民共和国
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水流入河川流域の医薬品汚染ポテンシャルマップ-モデル河川黒瀬川での調査-2009

    • Author(s)
      杉原数美,尾川雄一,佐光華佳,佐能正剛,清水良,北村繁幸,太田茂
    • Organizer
      フォーラム衛生薬学・環境トキわシコロジー
    • Place of Presentation
      宜野湾市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009

    • Author(s)
      尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] HYDROXYLATED POL YBROMINATED DIPHENYL ETHERS INTERRACT WITH THYROID HORMONE AND ESTROGEN RECEPTORS2009

    • Author(s)
      Sugihara K, Kitamura S, Shinohara S, Iwase E, Uramaru N, Shigematsu H, Fujimoto N, Ohta S
    • Organizer
      DIOXIN2009
    • Place of Presentation
      北京市、中華人民共和国
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 水環境中医薬品類の紫外線による分解と毒性変動2009

    • Author(s)
      尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 水環境中医薬品類の紫外線による分解と非意図的生成物の分析2009

    • Author(s)
      尾川雄一, 杉原数美, 佐能正剛, 北村繁幸, 久保光志, 太田茂
    • Organizer
      フォーラム衛生薬学・環境トキシコロジー
    • Place of Presentation
      沖縄県宜野湾市
    • Data Source
      KAKENHI-PROJECT-21406005
  • [Presentation] 生活排水汚染水域の医薬品探索および環境動態の検討2008

    • Author(s)
      尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
    • Organizer
      フォーラム2008:衛生薬学・環境トキシコロジー
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 医薬品による環境汚染防止に向けての廃棄方法実態調査2008

    • Author(s)
      杉原数美,尾川雄一,佐能正剛,北村繁幸,久保光志,太田茂
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜市
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] 生活排水流入河川水および下水処理場流入・流出水中の医薬品探索2008

    • Author(s)
      尾川雄一,杉原数美,佐能正剛,北村繁幸,久保光志,太田茂
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜市
    • Year and Date
      2008-03-26
    • Data Source
      KAKENHI-PROJECT-20590122
  • [Presentation] Developmental changes of aldehyde oxidase activity in liver cytosol of young ehildren2007

    • Author(s)
      Y., Tayama, K., Sugihara, S., Kitamura, S., Ohta
    • Organizer
      8th International ISSX Meeting
    • Place of Presentation
      Sendai Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] Chimeric mice with humanized liver as a model to predict diazepam metabolism in humans.2007

    • Author(s)
      T., Inoue, K., Sugihara, S., Kitamura, H., Ohshita, T., Horie, S., Ohta
    • Organizer
      8th International ISSX Meeting
    • Place of Presentation
      Sendai Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] Screening of AhR-binding, estrogenic and antiandrogenic activities of benzophenone derivatives used as UV stabilizers and sunscreens2007

    • Author(s)
      K., sugihara, S., Shinohara, T., Suzuki, N., Fujimoto, S., Kitamura, S., Ohta
    • Organizer
      DIOXIN 2007
    • Place of Presentation
      Tokyo Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] A Parkinson's disease-related neurotoxin binds to tubulin.2007

    • Author(s)
      Ryuki, Kohta, Yaichiro, Kotake, Shunsuke, Izumi, Kazumi, Sugihara, Takamitsu, Hosoya, Toshiyuki, Hiramatsu, Yuko, Ohtsubo, Hiroko, Koyama, Masaaki, Suzuki, Shigeru, Ohta
    • Organizer
      Neuro 2007
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-09-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390037
  • [Presentation] In vivo and in vitro metabolism of zaleplon in chimeric mice with humanized liver2007

    • Author(s)
      C., Tanoue, K., Sugihara, S., Kitamura, T., Inoue, T., Horie, S., Ohta
    • Organizer
      8th, International ISSX Meeting
    • Place of Presentation
      Sendai Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] A Parkinson's disease-related neurotoxin binds to tubulin2007

    • Author(s)
      Ryuki, Kohta, Yaichiro, Kotake, Shunsuke, Izumi, Kazumi, Sugihara, Takamitsu, Hosoya, Toshiyuki, Hiramatsu, Yuko, Ohtsubo, Hiroko, Koyama, Masaaki, Suzuki, Shigeru, Ohta
    • Organizer
      Neuro2007
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-09-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18406004
  • [Presentation] Metabolism of carbamate pesticides by liver microsomes and plasma of human and rat2007

    • Author(s)
      S., Tange, S., Kitamura, K., Sugihara, S., Ohta
    • Organizer
      8th International ISSX Meeting
    • Place of Presentation
      Sendai Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] Parabens and phthalates : Their metabolism, AhR ligand activity, estrogenic Activity, and P450-inhibitory activity2007

    • Author(s)
      H., Oz-aki, S., Shinohara, S., Tange, K., Sugihara, S., Kitamura, S., Ohta
    • Organizer
      DIOXIN 2007
    • Place of Presentation
      Tokyo Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] Thyroid hormonal and estrogenic activity of OH-PCB and OH-PBDE in cell culture2007

    • Author(s)
      S., Kitamura, T., Suzuki, K., Sugihara, N., Uramaru, H., Kuroki, N., Fujimoto, S., Ohta
    • Organizer
      DIOXIN 2007
    • Place of Presentation
      Tokyo Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590118
  • [Presentation] オス型成長ホルモン曝露がマウス肝癌細胞(Hepa 1-6)のaldehyde oxidasa発現に与える影響

    • Author(s)
      藤田裕太郎,長島和也,堀川嫌太,清水 良,北村繁幸,太田 茂,杉原数美
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響~ラットin vivoにおける検討~

    • Author(s)
      田山剛高,杉原数美,三宅勝志,北村繁幸,太田茂
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 環境中医薬品類の塩素消毒による毒性発現

    • Author(s)
      杉原数美,高田 鑑,増田莉奈,大上 凌,小林秀文,清水 良,北村繁幸,太田 茂
    • Organizer
      第41回日本毒性学会学術年会
    • Place of Presentation
      神戸
    • Year and Date
      2014-07-02 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 医薬品の塩素処理による分解と変異原性発現

    • Author(s)
      藤田哲孝,泉 哲平,三好晃史,清水 良,小林秀文,北村繁幸,太田 茂,杉原数美
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] Effects of metabolism of UV-absorbers by rat liver microsomes on their nuclear receptor activation.

    • Author(s)
      Watanabe Y., Kojima H., Takeuchi S., Uramaru N., Sugihara K., Sanoh S., Ohta S., Kitamura S.
    • Organizer
      DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds

    • Author(s)
      Kojima H., Sanoh S., Takeuchi S., Sugihara K., Yoshinari K., Kitamura S.
    • Organizer
      54th Annual Meeting and ToxExpo (Society of Toxicology)
    • Place of Presentation
      San Diego, California, USA
    • Year and Date
      2015-03-22 – 2015-03-26
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] レポーターアッセイ系を用いた香粧品香料によるPXR、CAR、PPAR&#61537;およびAhR活性の評価

    • Author(s)
      渡部容子,小島弘幸,浦丸直人,藤本成明,杉原数美,吉成浩一,太田 茂,北村繁幸
    • Organizer
      フォーラム2014衛生薬学・環境トキシコロジー
    • Place of Presentation
      つくば
    • Year and Date
      2014-09-19 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] マウス肝aldehyde oxidase発現への脳下垂体の影響

    • Author(s)
      秋本有花,岡嵜明穂,増岡さゆり,濱岡裕美,清水 良,佐能正剛,太田 茂,北村繁幸,杉原数美
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 環境化学物質におけるカエル甲状腺ホルモン作用のアゴニストおよびアンタゴニスト活性

    • Author(s)
      佐能正剛,中村直樹,鈴木賢一,柏木啓子,花田秀樹,山本 卓,新海 正,杉原数美,藤本成明,北村繁幸,柏木昭彦,太田 茂
    • Organizer
      フォーラム2014衛生薬学・環境トキシコロジー
    • Place of Presentation
      つくば
    • Year and Date
      2014-09-19 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] Metabolic activation of cis- and trans- permethrine for estrogenic and anti-androgenic activities

    • Author(s)
      Sugihara K.,Tange N., Fujimoto N., Uramaru N., Ohta S., Kitamura S.
    • Organizer
      DIOXIN 2014. The 34th International Symposium on Halogenated Persistent Organic Pollutants,
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2014-08-31 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] アルデヒドオキシダーゼと薬物代謝・安全性研究

    • Author(s)
      佐能正剛,田山剛高,杉原数美,北村繁幸,Mineko Terao,Enrico Garattini, 太田 茂
    • Organizer
      第41回日本毒性学会学術年会
    • Place of Presentation
      神戸
    • Year and Date
      2014-07-02 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 薬物代謝酵素aldehyde oxidaseのマウス肝での性差発現と化学物質の影響

    • Author(s)
      杉原数美,岡嵜明穂,秋本有花,田山剛高,前田志津子,佐能正剛,北村繁幸,太田 茂
    • Organizer
      フォーラム2014衛生薬 学・環境トキシコロジー
    • Place of Presentation
      つくば
    • Year and Date
      2014-09-19 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 香粧品香料のヒトおよびラットPXR、CAR、PPARa、AhRに対するアゴニスト活性

    • Author(s)
      渡部容子,小島弘幸,浦丸直人,杉原数美, 吉成浩一, 太田 茂,北村繁幸.
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] 核内受容体PXRおよびCAR転写活性に対する甲状腺ホルモン構造類似物質の影響

    • Author(s)
      清水 良,渡部容子,浦丸直人,小島弘幸,武内伸治,黒木広明,太田 茂,北村繁幸,杉原数美
    • Organizer
      フォーラム2014衛生薬 学・環境トキシコロジー
    • Place of Presentation
      つくば
    • Year and Date
      2014-09-19 – 2014-09-20
    • Data Source
      KAKENHI-PROJECT-25340049
  • [Presentation] ラット in vivo におけるallopurinol代謝へのxanthine oxidase およびaldehyde oxidase活性の影響

    • Author(s)
      田山剛崇、杉原数美、三宅勝志、北村繁幸、太田 茂
    • Organizer
      第24回 日本医療薬学会年回
    • Place of Presentation
      名古屋
    • Year and Date
      2014-09-27 – 2014-09-28
    • Data Source
      KAKENHI-PROJECT-25460235
  • [Presentation] Allopurinol代謝に及ぼすaldehyde oxidase活性の影響~ラット in vivoにおける検討~

    • Author(s)
      田山剛崇、杉原数美、三宅勝志、北村繁幸、太田 茂
    • Organizer
      日本薬学会 第135年回
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-26 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25460235
  • 1.  OHTA Shigeru (60160503)
    # of Collaborated Projects: 21 results
    # of Collaborated Products: 158 results
  • 2.  KITAMURA Shigeyuki (40136057)
    # of Collaborated Projects: 20 results
    # of Collaborated Products: 202 results
  • 3.  FUJIMOTO Nariaki (40243612)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 46 results
  • 4.  YOSHIHARA Shinichi (00037607)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  KOTAKE Yaichiro (20335649)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 6.  Tayama Yoshitaka (80389121)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 20 results
  • 7.  SANOH Seigo (00552267)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 30 results
  • 8.  NISHIJIMA Wataru (20243602)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 9.  KASHIWAGI Akihiko (50106796)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  SHIMIZU RYOU (00570491)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 11.  WATANABE Hiromitu (00034653)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  URAMARU Naoto (90424069)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 24 results
  • 13.  TANIGUCHI Yoshihiko (30403520)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  渡部 容子 (60628056)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 15.  KOJIMA Hiroyuki (10414286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  MAEDA SHIZUKO (80435065)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 17.  NAKAMURA Shigenobu (30026843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  ARIZONO Koji (70128148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YAMASHITA Keisuke (40166666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TASHIRO Tomoko (50114541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  塚本 豊久 (40389101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 22.  佐和 章弘 (70389104)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  岡村 友理香 (20645890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  HORIGUCHI Aya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  TAKEUCHI Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  今岡 進
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  岡田 和嗣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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