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MAEYAMA Kazutaka  前山 一隆

ORCIDConnect your ORCID iD *help
Researcher Number 00157158
Other IDs
Affiliation (based on the past Project Information) *help 2008 – 2010: 愛媛大学, 大学院・医学系研究科, 教授
2007 – 2008: 愛媛大学, 大学院・医学研究科, 教授
2006: 愛媛大学, 大学院医学研究科, 教授
2006: 愛媛大学, 大学院医学系研究科, 教授
1993 – 2005: 愛媛大学, 医学部, 教授 … More
1991 – 1992: 東北大学, 医学部, 助教授
1988: Tohoku University School of Medicine, 医学部, 助手
1986: Tohoku University, Assist. Prof., 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Nanomaterials/Nanobioscience
Except Principal Investigator
Neurochemistry/Neuropharmacology / General medical chemistry / Respiratory organ internal medicine / Experimental pathology / General pharmacology / Embryonic/Neonatal medicine / Applied pharmacology
Keywords
Principal Investigator
ヒスタミン / Histamine / Histidine decarboxylase / 肥満細胞 / 好塩基球性白血病細胞 / カルシウム / ヒスチジン脱炭酸酵素 / アンペロメトリー / マイクロセンサ / Motion sickness … More / Peptic ulcer / Histamine depletion / Suicide substrate / alpha-Fluoromethylhistidine / α-フルオロメチルヒスチジン / αーフルオロメチルヒスチジン / ヒスタミン受容体 / 動揺病 / 十二指腸潰瘍 / マストミス / ヒスタミン涸渇 / 自殺基質 / フルオロメチルヒスチジン / mast cells / osmium-gel / real-time monitoring / electrochemical detection / rat basophilic leukemia cells (RBL-2H3) / microsensor / histamine oxidase / histamine / ラット好塩基球性白血病細胞 / ヒスタミン遊離 / オスミウム / マスト細胞 / オスミウムゲル / リアルタイムモニタリング / 電気化学検出法 / ラット好塩基球性白血病細胞(RBL-2H3) / ヒスタミンオキシダーゼ / MAST CELL DEFICIENT RATS / PAW EDEMA / RESTRAINT STRESS / GASTRIC SECRETION / IN VIVO MICRODIALYSIS / N^<tau>-METHYLHISTAMINE / HISTAMINE / MAST CELLS / ヒスタミン・ニューロン / N^7N-メチルヒスタミン / 炎症 / N^t-メチルヒスタミン / 足蹠浮腫 / N^τ-メチルヒスタミン / マイクロダイアリシス法 / 拘束水浸ストレス / 胃酸分泌 / 肥満細胞欠損ラット / F-actin / Antifungal drugs / Calcium channel / Thapsigargin / Basophilic leukemia cell line / Calsium / 細胞骨格 / 免疫抑制剤 / 過酸化水素 / F-アクチン / 抗真菌剤 / カルシウムチャネル / サプシガ-ギン / mast cell / basophilic leukemia cell / Calcium / αートキシン / ジアミン酸化酵素 / プロテインキナーゼC / トパキノ / カテコールアミン / トパキノン / 酵素電極 / 基質チャネル / アミンオキシダーゼ … More
Except Principal Investigator
ヒスタミン / ヒスチジン脱炭酸酵素 / Convulsion / Histamine / PET / 痙攣 / ノックアウトマウス / H2受容体 / H1受容体 / histamine <H_1> -receptor / DOPA decarboxylase / fluorescence immunohistochemistry histamine N-methyltransferase / neurotransmitter / histidine decarboxylase / histamine / 組織螢光抗体法 / ヒスタミンH1-受容体 / ヒスタミン-N-メチル基転移酵素 / ドーパ脱炭酸酵素 / ラット脳 / 神経伝達物質 / Knockout mice / Organic cation transporter / Acute Respiratory Distress Syndrome / 遺伝子欠損マウス / 有機陽イオントランスポーター / 急性呼吸促迫症候群 / EOD mice / pathogenomics / platelet function / mutant gene / susceptibility loci / linkage analysis / coat color / crescentic glomerulonephritis / 分子遺伝病理学 / 毛色変異 / マイクロサテライト解析 / 糸球体腎炎 / 自己免疫性疾患 / 突然変異 / シナモンタンパク質 / リコンビナントタンパク質 / EODマウス / ゲノム病理学 / 血小板機能 / 変異遺伝子 / 感受性遺伝子座 / リンケージ解析 / 毛色 / 半月体形成性腎炎 / Brain functions / Knock-out mice / Histidine decarboxylase / H2 receptor / H1 receptor / 脳機能 / ヒスタミンN-メチル基転移酵素 / H_2受容体 / H_1受容体 / 遺伝子改変動物 / ヒスチジン脱炭素酵素 / Dementia / Asthma / Histamine H3 receptor / ヒスタミンH_3受容体 / 痴呆 / 喘息 / ヒスタミンH3受容体 / Aging / Learning-Memory / 加令 / 学習・記憶 / 晩期障害 / 循環器障害 / 呼吸障害 / 極低出生体重児 / 気管支異形成症 / 心機能 / 肺機能 / 慢性肺疾患 / 低出生体重児 / 蛋白キナーゼC / トルエンジイソシアネート / ブラウンノルウェイラット / グルココルチコイド / ヒスタミンH1受容体 / 抗ヒスタミン薬 / ヒスチジン脱炭酸酵素遺伝子 / インターロイキン-4 / 個別化医療 / 科学的検証 / アレルギー疾患感受性遺伝子 / スプラタスト / 蛋白キナーゼC-δ / 初期療法 / 天然物医薬 / IL-4 / 鼻過敏症 / 疾患感受性遺伝子 / ヒスタミンH_1受容体 / 遺伝子発現 / アレルギー / ヒスタミン受容体 Less
  • Research Projects

    (15 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (34 People)
  •  Study about objective indices of chronic lung disease of very low birth weight infant and early intervention

    • Principal Investigator
      MURAO Kikuko
    • Project Period (FY)
      2008 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Ehime University
  •  Novel reatment method targeting the mechanism of histamineH_1 receptor gene expression

    • Principal Investigator
      FUKUI Hiroyuki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      The University of Tokushima
  •  マルチプルアミンセンサの開発Principal Investigator

    • Principal Investigator
      前山 一隆
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      Ehime University
  •  The role of organic cation transporters in acute respiratory distress syndrome

    • Principal Investigator
      OGASAWARA Masahito
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Ehime University
  •  A novel mutant gene inhibiting the progression of autoimmune glomerulonephritis

    • Principal Investigator
      NOSE Masato
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Ehime University
  •  Real-time monitoring of histamine released from a single histamine neuron with a histamine microsensor using recombinant histamine oxidasePrincipal Investigator

    • Principal Investigator
      MAEYAMA Kazutaka
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Ehime University
  •  Studies on Brain Histamine Neurons Using Gene-Targetted Mice

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University
  •  ヒスタミンの脳機能における役割の解明--国際学術共同研究をめざして

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University
  •  NEW DEVELOPMENT OF PHARMACOLOGICAL RESEARCH FOR HISTAMINE : USING MAST CELL DEFICIENT RATPrincipal Investigator

    • Principal Investigator
      MAEYAMA Kazutaka
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      EHIME UNIVERSITY
  •  Histamine and learning-memory and convulsion

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University Medical School
  •  Drug development with histamine H3 receptor as a target

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tohoku University
  •  REGULATORY MECHANISM OF HISTAMINE RELEASE BY CA LCIUM : USING RAT BASOPHILIC LEUKEMIA CELL LINEPrincipal Investigator

    • Principal Investigator
      MAEYAMA Kazutaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      EHIME UNIVERSITY
  •  REGULATION OF HISTAMINE RELEASE AND SYNTHESIS; USING BASOPHILIC LEUKEMIA CELL LINESPrincipal Investigator

    • Principal Investigator
      MAEYAMA Kazutaka
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Is an Inhibitor of Histamine-Forming Enzyme a New Type of "Anti-histamine" ?Principal Investigator

    • Principal Investigator
      MAEYAMA Kazutaka, 渡辺 建彦
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      General pharmacology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Histamine as a neurotransmitter: Fluorescence immunohistochemistry of its synthetic and degradative enzymes and purification of histamine receptor protein.

    • Principal Investigator
      WATANABE Takehiko
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      TOHOKU UNIVERSITY
      Osaka University

All 2009 2008 2007 2006 2005

All Journal Article Presentation Patent

  • [Journal Article] Kujin suppresses histamine signaling at transcriptional level in toluene 2, 4-diisocyanate-sensitized rats2009

    • Author(s)
      Dev S, Mizuguchi H, Das AK, Maeyama K, Horinaga S, Kato S, Tamada M, Hattori M, Umehara H, Fukui H
    • Journal Title

      J Pharmacil Sci 109(4)

      Pages: 606-617

    • NAID

      10025736075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390167
  • [Journal Article] Suppression of histamine signaling by probiotic Lac-B : a possible mechanism of its anti allergic effect2008

    • Author(s)
      Dev S, Mizuguchi H, Matsushita C, Das AK, Maeyama K, Umehara H, Ohtoshi T, Kojima J, Nishida K, Takahashi K, Fukui H.
    • Journal Title

      J Pharmacol Sci 107(2)

      Pages: 159-166

    • NAID

      10024320878

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390167
  • [Journal Article] Dexamethasone suppresses histamine synthesis by repressing both transcription and activity of HDC in allergic rats2006

    • Author(s)
      Kitamura Y, Das AK, Murata Y, Maeyama K., Dev S, Wakayama Y, Kalbi B, Takeda N, Fukui H.
    • Journal Title

      Allergol Int 55(3)

      Pages: 279-286

    • NAID

      10019286494

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390167
  • [Journal Article] マスト細胞欠損動物から見えてきたもの2006

    • Author(s)
      前山一隆
    • Journal Title

      愛媛医学 25

      Pages: 220-226

    • Data Source
      KAKENHI-PROJECT-17651072
  • [Journal Article] Nuclear receptors as targets for drug development : peroxisome proliferator-activatedf receptor gamma in mast cells :2005

    • Author(s)
      Maeyama K.
    • Journal Title

      J pharmacol Sci 97(2)

      Pages: 190-194

    • Data Source
      KAKENHI-PROJECT-17651072
  • [Patent] 有機物質直接吸着超微粒子およびその複合体2008

    • Inventor(s)
      福井裕行、竹田篤、小駒益弘、見尾光庸、前山一隆
    • Industrial Property Number
      2008-074548
    • Filing Date
      2008
    • Data Source
      KAKENHI-PROJECT-18390167
  • [Presentation] 乳酸菌によるアレルギー性鼻炎改善作用2007

    • Author(s)
      松下知世、Shrabanti Dev、Asish K. Das、前山一隆、大利隆行、西田清隆、水口博之、小嶋純、福井裕行
    • Organizer
      第11回日本ヒスタミン学会
    • Place of Presentation
      富山市民プラザ、富山市
    • Year and Date
      2007-12-15
    • Data Source
      KAKENHI-PROJECT-18390167
  • 1.  WATANABE Takehiko (70028356)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  YANAI Kazuhiko (50192787)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  YAMATODANI Atsushi (30116123)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  ONODERA Kinji (40133988)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  OHTSU Hiroshi (60250742)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  OGASAWARA Masahito (00325367)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  FUKUI Hiroyuki (90112052)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 8.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TANIZAWA Katsuyuki (20133134)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  丹羽 修 (70392644)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TAKEDA Noriaki (30206982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  KAWAZOE Kazuyoshi (00248296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MIZUGUCHI Hiroyuki (40247838)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  KASHIWADA Yoshiki (30169429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NEMOTO Hisao (30208293)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MURAO Kikuko (20444755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TANNO Yasuo (20133944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  MEGURO Ken-ichi (90239559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ICHINOSE Masakazu (80223105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ADACHI Naoto (50253315)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MOCHIZUKI Takatoshi (40263933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  GOTOH Yoshinori (10162166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  NOSE Masato (70030913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ONO Masao (20302218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YAMAUCHI Kohei (20200579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SAITO Shouichirou (60325371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YAGI Naoto (80133940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  MATSUNAGA Tohru (10101271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  檜垣 高史 (60253308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  太田 雅明 (40512174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SAKAKIBARA Ryuzo (30127229)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  長田 久美子 (90068502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  八木 忍 (10111296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  KAWAGUCHI-NAGATA Kumiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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