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Shohab Youssefian  S Youssefian

ORCIDConnect your ORCID iD *help
… Alternative Names

S Youssefian  ショハブ ユーセフィアン

ユセフィアン ショハブ  ユセフィアン ショハブ

ユーセフィアン ショハブ  ユーセフィアン ショハブ

YOUSSEFIAN Shohab  ユ-セフィアン ショハブ

YOUSSEFIAN SHOHAB  ユ-セフィアン ショハブ

SHOHAB YOUSSEFIAN

YOUSSEFIAN S.  YOUSSEFIAN S

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Researcher Number 00210576
Other IDs
Affiliation (Current) 2022: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2017 – 2021: 京都大学, 医学研究科, 教授
2001: 秋田県立大学, 生物資源科学部, 助教授
2000: 秋田県立大学, 附属生物工学研究所, 助教授
1999: 秋田県立大学, 生物資源科学部, 助教授
1996 – 1997: 秋田県立農業短期大学, 附属生物工学研究所, 助教授 … More
1993 – 1995: 秋田県立農業短期大学, 附属生物工学研究所, 講師
1991: 秋田県立農業短期大学, 附属生物工学研究所, 講師
1991: Biotechnology Institute, Molecular Genetics, Lecturer, 講師
1990: 秋田県立農業短期大学, 生物工学研究所, 講師
1989: 秋田県立農業短期大学, 附属生物工学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
植物生理
Except Principal Investigator
植物生理学 / Complex systems / Society medicine, Nursing, and related fields / Basic Section 56010:Neurosurgery-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords
Principal Investigator
wgp / 小麦 / トランスジェニック植物 / wgp7 / Wgp / 酸素ストレス / 小分子G-蛋白 / コムギ / ras遺伝子 / GTP結合タンパク質 … More / 組み換えタバコ / プロモーター解析 / WHEAT / SMALL G PROTEINS / SO_2 / NO_2 / OXiDATIVS STRESS / TRANSGENIC PLANTS / G蛋白質 / 酸化ストレス / GTPase / 細胞死 / 傷応答 / 一過的解析 / 傷 / 病原体感染 / 二酸化硫黄 / 二酸化窒素 / パラコート / wheat / GTP / small G protein / oxidative stress / sulphur dioxide / nitrogen dioxide / transgenic plants / accessory proteins … More
Except Principal Investigator
組換えタバコ / rgp1 / RNF213 / もやもや病 / 環境汚染 / イオウ化合物 / システイン合成酵素 / 酸性雨 / 硫化水素 / DNAのメチル化 / 矮性発現 / 低分子量GTP結合タンパク質 / ras関連遺伝子 / イネ / アザシチジン / DNAメチル化 / rasー関連遺伝子 / 矮性植物 / GTP結合蛋白質 / rga1 / 矮性イネ / フザシチジン / DNA methylation / dwarfism / small GTP-binding protein / ras-related gene / Oryza sativa / azacytidine / transgenic tobacco / RNF213-R4810K / Arterial-Stenosis / ER stress / Mitotic failure / 腸内細菌 / ウイルス抗体の保有状況 / E3 ligase / AAA+ / R4810K / Apoptosis / 循環器疾患 / 脳卒中 / R4810K変異 / 血管閉塞性病変 / 疼痛 / 温度 / 気象環境 / 細胞内輸送 / ナトリウムチャネル / 血管閉塞性疾患 / 細胞内シグナル / 小児四肢疼痛発作症 / SCN11A / SCN10A / モデルマウス Less
  • Research Projects

    (10 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (24 People)
  •  Elucidation of infantile episodic limb pain mechanism induced by cold exposure

    • Principal Investigator
      奥田 裕子
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kyoto University
  •  Investigation of mechanisms of pain evoked by meteorological environment

    • Principal Investigator
      原田 浩二
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Research Field
      Society medicine, Nursing, and related fields
    • Research Institution
      Kyoto University
  •  もやもや病や脳梗塞の遺伝性リスク因子の機能解析

    • Principal Investigator
      手塚 徹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Kyoto University
  •  Mechanism and processe of stenoocclusive vascular diseases caused by RNF213 mutation in inflammatory cellular society

    • Principal Investigator
      小泉 昭夫
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Kyoto University
  •  Role of a small GTP-binding Protein in Oxidative Stress-Induced Cell Death in PlantsPrincipal Investigator

    • Principal Investigator
      ユセフィアン ショハブ (ユーセフィアン ショハブ)
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      植物生理
    • Research Institution
      Akita Prefectural University
  •  Characterization of a plant gene encoding a small GTP-binding protein that is specifically induced by SO_2 and NO_2Principal Investigator

    • Principal Investigator
      YOUSSEFIAN Shohab
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      植物生理
    • Research Institution
      Biotechnology Institute, Akita Prefectural College of Agriculture
  •  イオウを含む環境汚染物質の植物による浄化

    • Principal Investigator
      SANO Hiroshi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Akita Prefectural College of Agriculture
  •  Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

    • Principal Investigator
      YOUSSEFIAN SHOHAB
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      植物生理
    • Research Institution
      Akita Prefectural College of Agriculture
  •  Characterization of plant genes encoding signal-transducing GTP-binding proteinsPrincipal Investigator

    • Principal Investigator
      SHOHAB YOUSSEFIAN
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      植物生理
    • Research Institution
      Akita Prefectural College of Agriculture
  •  Regulation of plant expression by DNA methylation

    • Principal Investigator
      SANO Hiroshi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      植物生理学
    • Research Institution
      Akita Prefectural College of Agriculture

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Socio‐economic factors do also matter: comments on the article “Can climatic factors explain the differences in COVID-19?incidence and severity across the spanish regions?: an ecological study”2021

    • Author(s)
      Phosri Arthit、Cao Yang、Harada Sassa Mariko、Harada Kouji H.
    • Journal Title

      Environmental Health

      Volume: 20 Pages: 17-17

    • DOI

      10.1186/s12940-021-00701-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20308
  • [Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFkB activation and apoptosis in an AAA+domain-dependent manne2020

    • Author(s)
      Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
    • Journal Title

      Biochem Biophys Res Commun

      Volume: - Pages: 668-674

    • DOI

      10.1016/j.bbrc.2020.02.024

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786
  • [Journal Article] Moyamoya Disease and Spectrums of RNF213 Vasculopathy.2020

    • Author(s)
      Bang OY, Chung JW, Kim DH, Won HH, Yeon JY, Ki CS, Shin HJ, Kim JS, Hong SC, Kim DK, Koizumi A
    • Journal Title

      Translational Stroke Research

      Volume: -

    • DOI

      10.1007/s12975-019-00743-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Journal Article] Mechanical allodynia triggered by cold exposure in mice with the Scn11a p.R222S mutation: a novel model of drug therapy for neuropathic pain related to NaV1.92020

    • Author(s)
      Matsubara Yosuke、Okuda Hiroko、Harada Kouji H.、Youssefian Shohab、Koizumi Akio
    • Journal Title

      Naunyn-Schmiedeberg's Archives of Pharmacology

      Volume: 394 Pages: 299-306

    • DOI

      10.1007/s00210-020-01978-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K20308
  • [Journal Article] Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis.2019

    • Author(s)
      Okazaki S, Koizumi A 他26名(27番目)
    • Journal Title

      Circulation.

      Volume: 139 Pages: 295-298

    • DOI

      10.1161/circulationaha.118.038439

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-19K06922, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H03596
  • [Journal Article] Prevalence of RNF213 p.R4810K Variant in Early-Onset Stroke With Intracranial Arterial Stenosis2019

    • Author(s)
      Kamimura Teppei、Okazaki Shuhei、Morimoto Takaaki、Kobayashi Hatasu、Harada Kouji、Tomita Tsutomu、Higashiyama Aya、Yoshimoto Takeshi、Takahashi Jun C.、Nakagawara Jyoji、Koga Masatoshi、Toyoda Kazunori、Maruyama Hirofumi、Koizumi Akio、Ihara Masafumi
    • Journal Title

      Stroke

      Volume: 50 Pages: 1561-1563

    • DOI

      10.1161/strokeaha.118.024712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K06922, KAKENHI-PROJECT-19K10608, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-17H04670
  • [Journal Article] Dysregulation of RNF213 promotes cerebral hypoperfusion2018

    • Author(s)
      Morimoto T, Enmi J, Hattori Y, Iguchi S, Saito S, Harada K, Okuda H, Mineharu Y, Takagi Y, Youssefian S, Iida H, Miyamoto S, Ihara M, Kobayashi H, Koizumi A.
    • Journal Title

      Sci Rep.

      Volume: 8 Pages: 3607-3607

    • DOI

      10.1038/s41598-018-22064-8

    • NAID

      120006510289

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-15H04271, KAKENHI-PROJECT-15K19243, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05437, KAKENHI-PROJECT-15K19963
  • [Journal Article] Familial episodic limb pain in kindreds with novel Nav1.9 mutations2018

    • Author(s)
      Kabata R, Okuda H, Noguchi A, Kondo D, Fujiwara M, Hata K, Kato Y, Ishikawa K, Tanaka M, Sekine Y, Hishikawa N, Mizukami T, Ito J, Akasaka M, Sakurai K, Yoshida T, Minoura H, Hayashi T, Inoshita K, Matsuyama M, Kinjo N, Cao Y, Inoue S, Kobayashi H, Harada KH, Youssefian S, Takahashi T, Koizumi A.
    • Journal Title

      PLOS ONE

      Volume: 13

    • DOI

      10.1371/journal.pone.0208516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-20K20308
  • [Journal Article] Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice.2018

    • Author(s)
      Kobayashi Hatasu、Kabata Risako、Kinoshita Hideyuki、Morimoto Takaaki、Ono Koh、Takeda Midori、Choi Jungmi、Okuda Hiroko、Liu Wanyang、Harada Kouji H、Kimura Takeshi、Youssefian Shohab、Koizumi Akio
    • Journal Title

      Pulmonary Circulation

      Volume: - Pages: 204589401877815-204589401877815

    • DOI

      10.1177/2045894018778155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17J04066, KAKENHI-PROJECT-15K09137, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06397
  • [Presentation] 小児四肢疼痛発作症の神経過興奮メカニズム解明のためのNav1.8欠損マウスの作出2021

    • Author(s)
      奥田裕子、竹谷朱、小林果、土生敏行、原田浩二、ユーセフィアン・ショハブ、小泉昭男
    • Organizer
      第91回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K20308
  • [Presentation] もやもや病感受性遺伝子産物RNF213 の結合蛋白質 の同定2020

    • Author(s)
      崔 廷米、武田 美都里、小林 果、手塚 徹、 原田 浩二、小泉 昭夫、Youssefian Shohab
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] RNF213 調節不全は両側総頸動脈狭窄マウスモデル の脳低灌流を悪化させる2020

    • Author(s)
      小林 果、森本 貴昭、原田 浩二、奥田 裕子、 Shohab Youssefian、及川 伸二、村田 真理子、 小泉 昭夫
    • Organizer
      第90回日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] Rnf213遺伝子改変マウスにおける免疫細胞・血清サイトカインの系統的解析2019

    • Author(s)
      小林 果, 西村 泰光, 奥田 裕子, 原田 浩二, 加畑 理咲子, 武田 美都里, 崔 廷米, Youssefian Shohab, 大槻 剛巳, 小泉 昭夫
    • Organizer
      第89回日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] もやもや病感受性遺伝子産物RNF213のユビキチンリガーゼ活性の検討2019

    • Author(s)
      武田 美都里, 手塚 徹, 金 びん秀, 西出 旭, 崔 廷米, 原田 浩二, 小泉 昭夫, ショハブ・ユーセフィアン
    • Organizer
      第89回日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] もやもや病感受性遺伝子RNF213の結合分子の同定2019

    • Author(s)
      崔 廷米, 井上 令一, 武田 美都里, 小林 果, 手塚 徹, 原田 浩二, 小泉 昭夫, Youssefian Shohab
    • Organizer
      第89回日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] もやもや病タンパク質RNF213 のE3 ligase活性の機能的評価2018

    • Author(s)
      武田美都里、キム ミンソ、小林果、原田浩二、土生敏行、小泉昭夫、ユーセフィアン ショハブ
    • Organizer
      第88回 日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] The Prevalence of RNF213 p.R4810K Variant is High in Juvenile-Onset Stroke Patients With Intracranial Arterial Stenosis2018

    • Author(s)
      Teppei Kamimura, Shuhei Okazaki, Takaaki Morimoto, Hatasu Kobayashi, Kouji Harada, Tsutomu Tomita, Aya Higashiyama, Jun C Takahashi, Jyoji Nakagawara, Kazunori Toyoda, Akio Koizumi, Masafumi Ihara
    • Organizer
      International Stroke Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06397
  • [Presentation] mysterin 遺伝子の肺高血圧症患者遺伝子スクリーニングおよびマウスモデルによる解析2018

    • Author(s)
      小林果、加畑理咲子、木下秀之、森本貴昭、武田美都里、崔廷米、奥田裕子、原田浩二、Youssefian Shohab、小泉昭夫
    • Organizer
      第88回 日本衛生学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06397
  • 1.  SANO Hiroshi (20178809)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  小泉 昭夫 (50124574)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 3.  手塚 徹 (50312319)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  小林 果 (70542091)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 5.  原田 浩二 (80452340)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 6.  奥田 裕子 (30709663)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  土生 敏行 (70346071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  高橋 勉 (20270845)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  尾野 恭一 (70185635)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Kim Minsoo (50466835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  水島 恒裕 (90362269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IIDA Hidehiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  SAITO Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  MORIMOTO takaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  MIYAMOTO susumu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 16.  KINOSHITA Hideyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  CHOI JUNGMI
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 18.  岡崎 周平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 19.  平田 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  猪原 匡史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 21.  高橋 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  高木 康志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  峰晴 陽平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  森 泰生
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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