Mizushima Tsunehiro 水島恒裕

… Alternative Names

MIZUSHIMA Tsunehiro 水島恒裕

Less

Researcher Number	90362269
Other IDs
External Links
Affiliation (Current)	2025: 兵庫県立大学, 理学研究科, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 兵庫県立大学, 理学研究科, 教授 2020: 兵庫県立大学, 生命理学研究科, 教授 2011 – 2018: 兵庫県立大学, 生命理学研究科, 教授 2011 – 2012: 兵庫県立大学, 大学院・生命理学研究科, 教授 2008 – 2011: Nagoya City University, 大学院・薬学研究科, 准教授 … More 2008 – 2009: 名古屋市立大学, 薬学研究科, 准教授 2007: Nagoya University, 大学院・工学研究科, 助教 2006: 名古屋大学, 大学院工学研究科, 助手 2004 – 2005: 名古屋大学, 大学院・工学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Biological Sciences / Functional biochemistry Except Principal Investigator Biological Sciences / Basic Section 56010:Neurosurgery-related / Basic Section 37030:Chemical biology-related / Bacteriology (including Mycology) / Structural biochemistry
Keywords	Principal Investigator X線結晶構造解析 / プロテアソーム / 蛋白質分解 / 蛋白質 / 超分子複合体 / エフェクター / ユビキチン / 構造生物学 / シャペロン / ユビキチンリガーゼ … More / SCFユビキチンリガーゼ / 糖鎖 / 構造解析 / 細菌 / 赤痢菌 / Ｘ線結晶構造解析 / タンパク質 / 品質管理 / 分子認識 / 制御因子PA700 / 酵素反応 / IpaH / ユビキチン修飾経路 / OspI / 複合体構造 / エフェクタータンパク質 / ユビキチン経路 / Ｘ線化粧構造解析 / 分子認識及び相互作用 / 四次構造形成 / 品質管管理 / αリング / Dmp1-Dmp2複合体 / タンパク質分解 … More Except Principal Investigator 糖鎖 / 結晶構造解析 / NMR / 細胞内シグナル / 血管閉塞 / 血管閉塞性疾患 / RNF213 / シグナル伝達 / もやもや病 / 蛋白質分解 / 抗菌剤 / ケミカルバイオロジー / 病原細菌 / 炎症 / 病原性 / 細菌 / UBC13 / NF-kB / TRAF6 / 脱アミド化 / 自然免疫 / T3SS / Shigella flexneri / 病原性大腸菌 / レクチン / 品質管理 / ユビキチン / 細胞内レクチン / ERAD / 薬学 / 分子認識 / 脳神経疾患 / 蛋白質 Less

ユビキチンリガーゼが制御する病原菌感染と生体防御応答の構造生物学的解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  University of Hyogo
New antibiotics development
- Principal Investigator
  
  KIM MINSOO
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Kyoto University
Structural studies of infection mechanisms targeting the NF-kB pathway by pathogenic bacterial effectorsPrincipal Investigator
- Principal Investigator
  
  Mizushima Tsunehiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  University of Hyogo
Functional analysis of heritable risk factors for moyamoya disease and stroke
- Principal Investigator
  
  Tezuka Tohru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyoto University
Structural and functional analyses of bacterial ubiquitin ligasesPrincipal Investigator
- Principal Investigator
  
  Mizushima Tsunehiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Hyogo
Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infectionPrincipal Investigator
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
Structural studies for specific recognition of ubiquitin signalsPrincipal Investigator
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
Structural analyses of bacterial effectors and their mechanisms of infectionPrincipal Investigator
- Principal Investigator
  
  MIZUSHIMA TSUNEHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
26Sプロテアソーム複合体構造解析による超分子作動機構に関する研究Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Hyogo
In vitro reconstitution of eukaryotic proteasomePrincipal Investigator
- Principal Investigator
  
  MIZUSHIMA Tsunehiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Hyogo
A bacterial effector deamidates UBC13 to dampen the inflammatory response
- Principal Investigator
  
  SANADA Takahito
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo
20Sプロテアソーム複合体構築に関与するシャペロン蛋白質の構造及び作用機構解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
Elucidation of structural basis for molecular recognition and supramolecular complex formation of intracellular lectins involved in post-endoplasmic reticulum quality control
- Principal Investigator
  
  KATO Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities
NMR構造生物学に基づいた薬物相互作用の解析と神経変性疾患への治療応用
- Principal Investigator
  
  山口芳樹
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
X線結晶構造解析による26Sプロテアソーム蛋白質分解酵素複合体の構造及び機能解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
構造生物学的アプローチによる小胞体関連分解装置の分子認識と作動機構の解明
- Principal Investigator
  
  加藤晃一
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institutes of Natural Sciences Okazaki Research Facilities
新規シャペロンDmp1/2の構造解析を基盤としたプロテアソームの分子集合機構Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya City University
  Nagoya University
Structural analysis of the quality control mechanism of glycol proteins by SCF Fbs ubiquitin ligase.Principal Investigator
- Principal Investigator
  
  MIZUSHIMA Tsunehiro
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya City University
  Nagoya University
26Sプロテアソームによる巨大蛋白質複合体の選択的蛋白質分解機構解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
26SプロテアソームのX線結晶構造解析による巨大蛋白質複合体の分解機構解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
新しい糖鎖機能の構造学的解明を目指した糖鎖認識Fbox蛋白質のX線結晶構造解析Principal Investigator
- Principal Investigator
  
  水島恒裕
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University

[Book] 蛋白質核酸酵素融合発展する構造生物学とケミカルバイオロジーの最前線2009
- Author(s)
  水島恒裕、田中啓二
- Total Pages
  1716
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-19770080
[Book] 実験医学増刊号タンパク質の分解機構 (SCF^<Fbs1>の構造と機能分担執筆)2008
- Author(s)
  水島恒裕、吉田雪子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18054011
[Book] 実験医学増刊号タンパク質の分解機構(SCF^<Fbs1>の構造と機能分担執筆)2008
- Author(s)
  水島恒裕、吉田雪子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19770080
[Book] 実験医学増刊号タンパク質の分解機構 (SCF^<Fbs1>の構造と機能分担執筆)2008
- Author(s)
  水島恒裕、吉田雪子
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19044018
[Book] 実験医学増刊号タンパク質の分解機構(SCFFbs1の構造と機能分担執筆)2008
- Author(s)
  水島恒裕、吉田雪子
- Total Pages
  233
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural insight into the recognition of the linear ubiquitin assembly complex by <i>Shigella</i> E3 ligase IpaH1.4/2.52023
- Author(s)
  Hiragi Keito、Nishide Akira、Takagi Kenji、Iwai Kazuhiro、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 173 Issue: 4 Pages: 317-326
- DOI
  10.1093/jb/mvac109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04988, KAKENHI-PROJECT-20H03198, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05499
[Journal Article] Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress2023
- Author(s)
  Nishio Kazuya、Kawarasaki Tomoyuki、Sugiura Yuki、Matsumoto Shunsuke、Konoshima Ayano、Takano Yuki、Hayashi Mayuko、Okumura Fumihiko、Kamura Takumi、Mizushima Tsunehiro、Nakatsukasa Kunio
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 15 Pages: 1956-1975
- DOI
  10.1126/sciadv.adf1956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03198, KAKENHI-PROJECT-23K27126, KAKENHI-PROJECT-23K27130
[Journal Article] Active site structure of the <i>Shigella flexneri</i> effector OspI2022
- Author(s)
  Nishide Akira、Takagi Kenji、Kim Minsoo、Mizushima Tsunehiro
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2022.02.15.480433
- Open Access
- Data Source
  KAKENHI-PROJECT-18K14637, KAKENHI-PROJECT-20H03198
[Journal Article] Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase2021
- Author(s)
  Hiragi Keito、Nishio Kazuya、Moriyama Shu、Hamaguchi Tasuku、Mizoguchi Akira、Yonekura Koji、Tani Kazutoshi、Mizushima Tsunehiro
- Journal Title
  
  Journal of Structural Biology
  
  Volume: 213 Issue: 3 Pages: 107748-107748
- DOI
  10.1016/j.jsb.2021.107748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03198
[Journal Article] Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner2020
- Author(s)
  Takeda Midori、Tezuka Tohru、Kim Minsoo、Choi Jungmi、Oichi Yuki、Kobayashi Hatasu、Harada Kouji H.、Mizushima Tsunehiro、Taketani Shigeru、Koizumi Akio、Youssefian Shohab
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: - Issue: 3 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10608, KAKENHI-PROJECT-19J15073, KAKENHI-PROJECT-17K08786, KAKENHI-PLANNED-17H06397, KAKENHI-PROJECT-20H03790
[Journal Article] Shigella hijacks the glomulin?cIAPs?inflammasome axis to promote inflammation2018
- Author(s)
  Suzuki Shiho、Suzuki Toshihiko、Mimuro Hitomi、Mizushima Tsunehiro、Sasakawa Chihiro
- Journal Title
  
  EMBO Rep
  
  Volume: 19 Issue: 1 Pages: 89-101
- DOI
  10.15252/embr.201643841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14700, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-15H04341, KAKENHI-PROJECT-15H04730, KAKENHI-PROJECT-16K08772
[Journal Article] Structural analysis of a function-associated loop mutant of the substrate recognition domain of Fbs1 ubiquitin ligase.2016
- Author(s)
  Nishio, K., Yoshida, Y., Tanaka, K., Mizushima, T.
- Journal Title
  
  Acta Crystallographica Section F
  
  Volume: 72 Issue: 8 Pages: 619-626
- DOI
  10.1107/s2053230x16011018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-26000014
[Journal Article] A conserved island of BAG6/Scythe is related to ubiquitin domains and participates in short hydrophobicity recognition.2016
- Author(s)
  Tanaka, H., Takahashi, T., Xie, Y., Minami, R., Yanagi, Y., Hayashishita, M., Suzuki, R., Yokota, N., Shimada, M., Mizushima, T., Kuwabara, N., Kato, R., Kawahara, H.
- Journal Title
  
  FEBS J.
  
  Volume: 283 Issue: 4 Pages: 662-677
- DOI
  10.1111/febs.13618
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-14J05957, KAKENHI-PROJECT-26840029, KAKENHI-PLANNED-24112007, KAKENHI-PROJECT-16K14699
[Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016
- Author(s)
  Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
- Journal Title
  
  Nature Commun
  
  Volume: 7 Issue: 1 Pages: 12030-12030
- DOI
  10.1038/ncomms12030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
[Journal Article] Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.82016
- Author(s)
  K Takagi, et al
- Journal Title
  
  Acta Cryst
  
  Volume: F72 Issue: 4 Pages: 269-275
- DOI
  10.1107/s2053230x16002715
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-15H01174, KAKENHI-PROJECT-15H04341, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-16K14700
[Journal Article] The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3.2015
- Author(s)
  Kumanomidou T, Nishio K, Takagi K, Nakagawa T, Suzuki A, Yamane T, Tokunaga F, Iwai K, Murakami A, Yoshida Y, Tanaka K, Mizushima T.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 10 Pages: e0140366-e0140366
- DOI
  10.1371/journal.pone.0140366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H01172, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-25253019
[Journal Article] Conserved Mode of Interaction between Yeast Bro1 Family V Domains and YP(X)nL Motif-Containing Target Proteins2015
- Author(s)
  Yoko Kimura, Mirai Tanigawa, Junko Kawawaki, Kenji Takagi, Tsunehiro Mizushima, Tatsuya Maeda, Keiji Tanaka
- Journal Title
  
  Eukaryotic Cell
  
  Volume: 14 Issue: 10 Pages: 976-982
- DOI
  10.1128/ec.00091-15
- NAID
  120005671359
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440070, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-25291042, KAKENHI-PROJECT-26000014
[Journal Article] Bacterial Effectors and Their Functions in the Ubiquitin-Proteasome System: Insight from the Modes of Substrate Recognition2014
- Author(s)
  Kim M et. al
- Journal Title
  
  Cells
  
  Volume: 3 Issue: 3 Pages: 848-864
- DOI
  10.3390/cells3030848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-14J10879, KAKENHI-PROJECT-23000012, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] Kinetic, Thermodynamic and Structural Characterizations of Association between Nrf2-DLGex Degron and Keap1.2014
- Author(s)
  Fukutomi, T., Takagi, K., Mizushima, T., Ohuchi, N., and Yamamoto, M.
- Journal Title
  
  Moll Cell Biol.
  
  Volume: 34 Issue: 5 Pages: 832-846
- DOI
  10.1128/mcb.01191-13
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25870631
[Journal Article] The Shigella OspC3 effector inhibits Cspase-4, antagonizes inflammatory cell death, and promotes epithelial infection2013
- Author(s)
  Kobayashi T, et. al
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 5 Pages: 570-583
- DOI
  10.1016/j.chom.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23790471, KAKENHI-PUBLICLY-24117507, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigella flexneri effector OspI.2013
- Author(s)
  Nishide A, Kim M, Takagi K, Himeno A, Sanada T, Sasakawa C, Mizushima T.
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24370049
[Journal Article] Structural basis for the recognition of Ubcl3 by the Shigell a flexneri effector OspI2013
- Author(s)
  Nishide A, et. al
- Journal Title
  
  J Mol Bio.
  
  Volume: 425 Issue: 15 Pages: 2623-2631
- DOI
  10.1016/j.jmb.2013.02.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23689027, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24370049, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25870631
[Journal Article] Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.2013
- Author(s)
  Ichimura, Y., Waguri, S., Sou, Y., Kageyama, S., Hasegawa, J., Ishimura, R., Saito, T., Yang, Y., Kouno, T., Fukutomi, T., Hoshii, T., Atsushi, H., Takagi, K., Mizushima, T., Motohashi, H., Lee, M-S., Yoshimori, T., Tanaka, K., Yamamoto, M., and Komatsu, K.
- Journal Title
  
  Mol Cell
  
  Volume: 51 Issue: 5 Pages: 618-631
- DOI
  10.1016/j.molcel.2013.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-23247034, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790332, KAKENHI-PROJECT-24790967, KAKENHI-PLANNED-25111002, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631
[Journal Article] The proteasome : molecular machinery and pathophysiological roles2012
- Author(s)
  Tanaka, K., Mizushima, T., Saeki, Y.
- Journal Title
  
  Biol Chem.
  
  Volume: 393 Issue: 4 Pages: 217-234
- DOI
  10.1515/hsz-2011-0285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23657080
[Journal Article] New crystal structure of proteasome-dedicated chaperone Rpnl4 at 1.6 Å resolution.2012
- Author(s)
  Kim, S., Nishide, A., Saeki, Y., Takagi, K., Tanaka, K., Kato, K., Mizushima, T.
- Journal Title
  
  Acta Cryst F
  
  Volume: 68 Issue: 5 Pages: 517-521
- DOI
  10.1107/s1744309112011359
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23657080, KAKENHI-PROJECT-24657113
[Journal Article] A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex2012
- Author(s)
  H. Yagi, K. Ishimoto, T. Hiromoto, H. Fujita, T. Mizushima, Y. Uekusa, M. Yagi-Utsumi, E. Kurimoto, M. Noda, S. Uchiyama, F. Tokunaga, K. Iwai and K. Kato
- Journal Title
  
  EMBO reports
  
  Volume: 13 Pages: 462-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370050
[Journal Article] The proteasome : molecular machinery and pathophysiological roles2012
- Author(s)
  Tanaka, K., Mizushima, T., Saeki, Y
- Journal Title
  
  Biol.Chem
  
  Volume: 393 Pages: 217-234
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121525
[Journal Article] A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex.2012
- Author(s)
  H.Yagi, K.Ishimoto, T.Hiromoto, H.Fujita, T.Mizushima, Y.Uekusa, M.Yagi-Utsumi, E.Kurimoto, M.Noda, S.Uchiyama, F.Tokunaga, K. Iwai, and K.Kato
- Journal Title
  
  EMBO Rep.
  
  Volume: 13 Issue: 5 Pages: 462-468
- DOI
  10.1038/embor.2012.24
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107004, KAKENHI-PLANNED-22117006, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23390070, KAKENHI-PROJECT-23657075, KAKENHI-PROJECT-23870043
[Journal Article] Structural basis for specific recognition of Rpt1, an ATPase subunit of the 26S proteasome, by a proteasome-dedicated chaperone Hsm32012
- Author(s)
  Takagi K., Kim S., Yukii H., Ueno M., Morishita R., Endo Y., Kato K., Tanaka K., Saeki Y., Mizushima T.
- Journal Title
  
  J.Biol.Chem
  
  Volume: 287 Issue: 15 Pages: 12172-12182
- DOI
  10.1074/jbc.p112.345876
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23657080
[Journal Article] The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response2012
- Author(s)
  Sanada, T.
- Journal Title
  
  Nature
  
  Volume: 483 Issue: 7391 Pages: 623-626
- DOI
  10.1038/nature10894
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PLANNED-22117002, KAKENHI-PROJECT-22790403, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-23121525, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23689027, KAKENHI-PROJECT-23770203, KAKENHI-PROJECT-23790471
[Journal Article] 構造からみるプロテアソームの機能2011
- Author(s)
  水島恒裕、西尾和也
- Journal Title
  
  実験医学　増刊
  
  Volume: 29 Pages: 1875-1881
- Data Source
  KAKENHI-PROJECT-23657080
[Journal Article] Conformational dynamics of wild-type Lys-48-linked diubiquitin in solution2011
- Author(s)
  T. Hirano, O. Serve, M. Yagi-Utsumi, E. Takemoto, T. Hiromoto, T. Satoh, T. Mizushima and K. Kato
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 236 Pages: 37496-37502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370050
[Journal Article] Conformational dynamics of wild-type Lys-48-linked diubiquitin in solution.2011
- Author(s)
  T.Hirano, O.Serve, M.Yagi-Utsumi, E.Takemoto, T.Hiromoto, T.Satoh, T.Mizushima, and K.Kato
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286 Issue: 43 Pages: 37496-37502
- DOI
  10.1074/jbc.m111.256354
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20107004, KAKENHI-PROJECT-21370050, KAKENHI-PUBLICLY-22020037, KAKENHI-PUBLICLY-23121532, KAKENHI-PROJECT-23870043
[Journal Article] 構造から見るプロテアソームの機能2011
- Author(s)
  水島恒裕、西尾和也
- Journal Title
  
  実験医学
  
  Volume: 増刊、29 Pages: 1875-81
- Data Source
  KAKENHI-PROJECT-23657080
[Journal Article] Crystal Structure of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the Proteasome.2010
- Author(s)
  Kim S, Saeki Y, Fukunaga K, Suzuki A, Takagi K, Yamane T, Tanaka K, Mizushima T, Kato K
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 15159-15166
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025027
[Journal Article] Crystal Structure of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the Proteasome.2010
- Author(s)
  Kim S, Saeki Y, Fukunaga K, Suzuki A, Takagi K, Yamane T, Tanaka K, Mizushima T, Kato K
- Journal Title
  
  J.Biol.Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025027
[Journal Article] Crystal Structure of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the Proteasome.2010
- Author(s)
  Kim S, Saeki Y, Fukunaga K, Suzuki A, Takagi K, Yamane T, Tanaka K, Mizushima T, Kato
- Journal Title
  
  J. Biol. Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystallization and preliminary X-ray characterization of the Skp1-Fbg3 complex.2010
- Author(s)
  Kumanomidou T, Nakagawa T, Mizushima T, Suzuki A, Tokunaga F, Iwai K, Yoshida Y, Tanaka K, Yamane T
- Journal Title
  
  Acta Crystallographica Section F 66
  
  Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystal Stucture of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the Proteasome.2010
- Author(s)
  Kim S, Saeki Y, Fukunaga K, Suzuki A< Takagi K, Yamane T, Tanaka K, Mizushima T, Kato K
- Journal Title
  
  J.Biol.Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Crystallization and preliminary X-ray characterization of the Skp1-Fbg3 complex.2010
- Author(s)
  Kumanomidou T, Nakagawa T, Mizushima T, Suzuki A, Tokunaga F, Iwai K, Yoshida Y, Tanaka K, Yamane T
- Journal Title
  
  Acta Crystallographica Section F 66
  
  Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025027
[Journal Article] Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency2010
- Author(s)
  M. Nishio, Y. Kamiya, T. Mizushima, S. Wakatsuki, H. Sasakawa, K. Yamamoto, S. Uchiyama, M. Noda, A. R. McKay, K. Fukui, H.-P. Hauri and K. Kato
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 107 Pages: 4034-4039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370050
[Journal Article] Crystal Structure of Yeast Rpn14, a Chaperone of the 19S Regulatory Particle of the Proteasome.2010
- Author(s)
  Kim S, Saeki Y, Fukunaga K, Suzuki A, Takagi K, Yamane T, Tanaka K, Mizushima T, Kato K
- Journal Title
  
  J.Biol.Chem. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency2010
- Author(s)
  Nishio M, Kamiya Y, Mizushima T, Wakatsuki S, Sasakawa H, Yamamoto K, Uchiyama S, Noda M, McKay AR, Fukui K, Hauri HP, Kato K
- Journal Title
  
  Proc Natl Acad Sci U S A. 107
  
  Pages: 4034-4039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency2010
- Author(s)
  Nishio M, Kamiya Y, Mizushima T, Wakatsuki S, Sasakawa H, Yamamoto K, Uchiyama S, Noda M, McKay AR, Fukui K, Hauri HP, Kato K
- Journal Title
  
  Proc Natl Acad Sci USA. 107
  
  Pages: 4034-4039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystallization and preliminary X-ray characxterization of the SKp1-Fbg3 complex.2010
- Author(s)
  Kumanomidou T, Nakagawa, T, Mizushima T, Suzuki A< Tokunaga F, Iwai K, Yoshida Y, Tanaka K, Yamane T
- Journal Title
  
  Acta Crystallographica Section F 66
  
  Pages: 95-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency2010
- Author(s)
  M.Nishio, Y.Kamiya, T.Mizushima, S.Wakatsuki, H.Sasakawa, K.Yamamoto, S.Uchiyama, M.Noda, A.R.McKay, K.Fukui, H.-P.Hauri, K.Kato
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 107
  
  Pages: 4034-4039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370050
[Journal Article] Crystal structure of the deubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain.2009
- Author(s)
  Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21025027
[Journal Article] Crystal structure of the deubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain.2009
- Author(s)
  Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Crystal structure of the deubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain.2009
- Author(s)
  Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] 出芽酵母20Sプロテアソーム形成に関わるシャペロン複合体Dmp1/Dmp2の立体構造解析2008
- Author(s)
  八代田英樹、水島恒裕
- Journal Title
  
  細胞工学 27
  
  Pages: 474-475
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Structure of D-amino-acid amidase complexed with L-phenylalanine with L-phenylalanine amide: insight into D-stereospecificity of D-amino-acid amidase from Ochrobacterum anthropi SV32008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Acta Cryst. D 64
  
  Pages: 331-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes2008
- Author(s)
  Yashiroda H, Mizushima T, Okamoto K, Kameyama T, Hayashi H, Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K, Suzuki A, Hirano Y, Murata S, Kato K, Yamane T, Tanaka K
- Journal Title
  
  Nat Struct Mol Biol. 15
  
  Pages: 228-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008
- Author(s)
  Ichimura Y, Kumanomidou T, Sou Y, Mizushima, T, Ezaki, J, Ueno T, Kominami F Yamane T Tanaka K. Komatsu M
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 22847-22857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Structure of Damino-acid amidase complexed with Lphenylalanine with Lphenylalanine amide : insight into Dstereospecificity of D-amino-acid amidase from Ochrobacterum anthropi SV32008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Acta Cryst. D 64
  
  Pages: 331-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes2008
- Author(s)
  Yashiroda H, Mizushima T, Okamoto K, Kameyama T, Hayashi H, Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K, Suzuki A, Hirano Y, Murata S, Kato K, Yamane T, Tanaka K
- Journal Title
  
  Nat Struct Mol Biol. 15
  
  Pages: 228-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008
- Author(s)
  Ichimura Y, Kumanomidou T, Sou Y, Mizushima T, Ezaki, J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 22847-22857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] 出芽酵母20Sプロテアソーム形成に関わるシャペロン複合体Dmp1/Dmp2の立体構造解析2008
- Author(s)
  八代田英樹、水島恒裕
- Journal Title
  
  細胞工学 27
  
  Pages: 474-475
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] The novel structure of a pyridoxal 5'-phosphate-dependent fold-type I racemase, alpha-amino-epsiloncaprolactam racemase from Achromobacter obae.2008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Kawano T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Biochemistry 48
  
  Pages: 941-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes2008
- Author(s)
  Yashiroda H, Mizushima T, Okamoto K, Kameyama T, Hayashi H, Kishimoto T, Niwa S, Kasahara M, Kurimoto E, Sakata E, Takagi K, Suzuki A, Hirano Y, Murata S, Kato K, Yamane T, Tanaka K
- Journal Title
  
  Nat Struct Mol Biol. 15
  
  Pages: 228-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054011
[Journal Article] The novel structure of a pyridoxal 5'phosphatedependent fold-type Iracemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae2008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Kawano T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Biochemistry 48
  
  Pages: 941-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] 出芽酵母20Sプロテアソーム形成に関わるシャペロン複合体Dmp1/Dmp2の立体構造解析2008
- Author(s)
  八代田英樹、水島恒裕
- Journal Title
  
  細胞工学 27
  
  Pages: 474-475
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] The novel structure of a pyridoxal 5'-phosphate-dependent fold-type Iracemase, alpha-amino-epsilon-caprolactam racemase from Achromobacter obae2008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Kawano T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Biochemistry 48
  
  Pages: 941-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008
- Author(s)
  Ichimura Y, Kumanomidou T, Sou Y, Mizushima, T, Ezaki, J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 22847-22857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] Structure of D-amino-acid amidase complexed with L-phenylalanine with L-phenylalanine amide : insight into D-stereospecificity of D-amino-acid amidase from Ochrobacterum anthropi SV32008
- Author(s)
  Okazaki S, Suzuki A, Mizushima T, Komeda H, Asano Y, Yamane T
- Journal Title
  
  Acta Cryst : D 64
  
  Pages: 331-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20051010
[Journal Article] Structural basis for sorting mechanism of p62 in selective autophagy2008
- Author(s)
  Ichimura Y, Kumanomidou T, Sou Y, Mizushima, T, Ezaki, J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 22847-22857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for the selection of glycosylated substrates by SCF^<Fbsl> ubiquitin ligase.2007
- Author(s)
  Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, Yamane T, Tanaka K
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 5777-5781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Crystal structure of Ufc1, the Ufm1-conjugating enzyme2007
- Author(s)
  Mizushima T, Tatsumi K, Ozakai Y, Kawakami T, Suzuki A, Ogasahara K, Komatsu M, Kominami E, Tanaka K, Yamane T
- Journal Title
  
  Biochem Biophys Res Commun 362
  
  Pages: 1079-1084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054011
[Journal Article] Crystal structure of Ufc1, the Ufm1-conjugating enzyme2007
- Author(s)
  Mizushima T, Tatsumi K, Ozakai Y, Kawakami T, Suzuki A, Ogasahara K, Komatsu M, Kominami E, Tanaka K, Yamane T
- Journal Title
  
  Biochem Biophys Res Commun 362
  
  Pages: 1079-1084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for the selection of glycosylated substrates by SCF^<Fbs1>ubiquitin ligase.2007
- Author(s)
  Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, Yamane T, Tanaka K
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 5777-5781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase.2007
- Author(s)
  Shinzawa-Itoh K, Aoyama H, Muramoto K, Terada H, Kurauchi T, Tadehara Y, Yamasaki A, Sugimura T, Kurono S, Tsujimoto K, Mizushima T, Yamashita E, Tsukihara T, Yoshikawa S
- Journal Title
  
  EMBO Journal 26
  
  Pages: 17131-1725
- NAID
  120000861649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase.2007
- Author(s)
  Shinzawa-Itoh K, Aoyama H, Muramoto K, Terada H, Kurauchi T, Tadehara Y, Yamasaki A, Sugimura T, Kurono S, Tsujimoto K, Mizushima T, Yamashita E, Tsukihara T, Yoshikawa S
- Journal Title
  
  EMBO Journal 26
  
  Pages: 17131-1725
- NAID
  120000861649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase.2007
- Author(s)
  Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, Yamane T, Tanaka K
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 5777-5781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19770080
[Journal Article] Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase.2007
- Author(s)
  Shinzawa-Itoh K, Aoyama H, Muramoto K, Terada H, Kurauchi T, Tadehara Y, Yamasaki A, Sugimura T, Kurono S, Tsujimoto K, Mizushima T, Yamashita E, Tsukihara T, Yoshikawa S
- Journal Title
  
  EMBO Journal 26
  
  Pages: 17131-1725
- NAID
  120000861649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054011
[Journal Article] Structural basis for the selection of glycosylated substrates by SCF^<Fbs1> ubiquitin ligase.2007
- Author(s)
  Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, yamane T, Tanaka K
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 5777-5781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18054011
[Journal Article] Crystal structure of Ufcl, the Ufml-conjugating enzyme2007
- Author(s)
  Mizushima T, Tatsumi K, Ozakai Y, Kawakami T, Suzuki A, Ogasahara K, Komatsu M, Kominami E, Tanaka K, Yamane T
- Journal Title
  
  Biochem Biophys Res Commun 362
  
  Pages: 1079-1084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044018
[Journal Article] The Crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers.2006
- Author(s)
  Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T
- Journal Title
  
  Journal of Molecular Biology 355(4)
  
  Pages: 612-618
- Data Source
  KAKENHI-PROJECT-17053010
[Journal Article] The Crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers.2006
- Author(s)
  Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T
- Journal Title
  
  Journal of Molecular Biology 355(4)
  
  Pages: 612-618
- Data Source
  KAKENHI-PROJECT-16770072
[Journal Article] 糖鎖ユビキチンリガーゼの立体構造から明らかになった蛋白質分解のための糖鎖の役割2005
- Author(s)
  水島恒裕
- Journal Title
  
  日本結晶学会誌 47
  
  Pages: 197-203
- Data Source
  KAKENHI-PROJECT-16770072
[Journal Article] 糖鎖認識ユビキチンリガーゼの立体構造から明らかになった蛋白質分解のための糖鎖の役割2005
- Author(s)
  水島恒裕
- Journal Title
  
  日本結晶学会誌 47
  
  Pages: 197-203
- NAID
  10016467866
- Data Source
  KAKENHI-PROJECT-17053010
[Journal Article] Structural basis of sugar-recognizing ubiquitin ligase.2004
- Author(s)
  Mizushima T, Hirao T, Yoshida Y, et al.
- Journal Title
  
  Nature Structure & Molecular Biology. 11
  
  Pages: 365-370
- Data Source
  KAKENHI-PROJECT-16770072
[Journal Article] ユビキチンシステムの構造生物学2004
- Author(s)
  水島恒裕
- Journal Title
  
  医学のあゆみ 211
  
  Pages: 17-22
- Data Source
  KAKENHI-PROJECT-16770072
[Journal Article] Structural basis for the selection of glycosylated substrates by SCF^<Fbsl> ubiquitin ligase
- Author(s)
  T.Mizushima, Y.Yoshida, T.Kumanomidou, Y.Hasegawa, A.Suzuki, T.Yamane, K.Tanaka
- Journal Title
  
  Proc Natl Acad Sci U S A. (印刷中)
- Data Source
  KAKENHI-PROJECT-18054011
[Presentation] 病原細菌NEL型ユビキチンリガーゼの反応中間体構造解析2023
- Author(s)
  中村真唯子，平木慶人，小杉将吾，Kim Minsoo，水島恒裕
- Organizer
  令和5年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 病原細菌NEL型ユビキチンリガーゼの反応中間体構造解析2023
- Author(s)
  中村真唯子，平木慶人，小杉将吾，Kim Minsoo，水島恒裕
- Organizer
  第9回バイオダイナミクス研究科
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Legionella菌Cif様タンパク質のX線結晶構造解析2023
- Author(s)
  馬場拓海，平木慶人，粕谷航平，小倉実，西出旭， Kim Minso，水島恒裕
- Organizer
  令和5年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Legionella菌Cif様タンパク質のX線結晶構造解析2023
- Author(s)
  馬場拓海，平木慶人，粕谷航平，小倉実，西出旭， Kim Minso，水島恒裕
- Organizer
  第9回バイオダイナミクス研究科
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] クエン酸合成酵素の構造変化を識別するF-boxタンパク質Ucc12022
- Author(s)
  西尾和也・中務邦雄・嘉村巧・水島恒裕
- Organizer
  第5回　バイオダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] X線結晶構造解析による赤痢菌エフェクターIpaH1.4/2.5のLUBAC阻害機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  令和4年度日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5基質認識ドメインの構造及び基質認識機構の解析2022
- Author(s)
  平木慶人・西出旭・高木賢治・Kim Minsoo・水島恒裕
- Organizer
  第5回　バイオダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5のX線結晶構造解析および機能解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第67回　日本生化学会　近畿支部例会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクター IpaH1.4/2.5 による直鎖状ポリユビキチン鎖生成酵素 (LUBAC) 認識機構の解析2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第21回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 病原菌エフェクターによる宿主防御応答阻害機構の解明2021
- Author(s)
  水島恒裕
- Organizer
  公益財団法人アステラス病態代謝研究会　第51回研究報告会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターIpaH1.4/2.5によるLUBAC複合体認識機構の解明2021
- Author(s)
  平木慶人・西出旭・高木賢治・岩井一宏・Kim Minsoo・水島恒裕
- Organizer
  第4回ピコバイオロジー研究会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] Ｘ線結晶構造解析による赤痢菌エフェクターIpaH1.4及び2.5の基質認識機構の解析2020
- Author(s)
  平木慶人、西出旭、高木賢治、Kim Minsoo、水島恒裕
- Organizer
  日本結晶会　令和2年度年会
- Data Source
  KAKENHI-PROJECT-20H03198
[Presentation] 赤痢菌エフェクターによる免疫反応抑制機構の解明2019
- Author(s)
  平木慶人、高木賢治、Kim Minsoo、水島恒裕
- Organizer
  技術・人材マッチング交流会
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] 赤痢菌エフェクタータンパク質IpaH1.4/2.5によるLUBAC複合体認識機構の解析2018
- Author(s)
  平木慶人、高木賢治、Kim Minsoo、水島恒裕
- Organizer
  第65回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] Structural basis for the recognition of citrate synthase, Cit2 by F-box protein Ucc12017
- Author(s)
  Kazuya Nishio, Syu Moriyama, Kunio Nakatsukasa, Takumi Kamura and Tsunehiro Mizushima
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for school year of 2016
- Place of Presentation
  兵庫県立先端科学技術支援センター (兵庫県・赤穂郡上郡町)
- Year and Date
  2017-03-13
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] ユビキチン-プロテアソーム経路による生命制御の分子メカニズム2017
- Author(s)
  水島恒裕
- Organizer
  徳島大学薬学部講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] バクテリアの感染戦略：エフェクターによる宿主防御経路の阻害機構2017
- Author(s)
  水島恒裕
- Organizer
  県立健康生活科学研究所・理学部合同研究発表会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] バクテリアの感染戦略：エフェクターによる宿主防御経路の阻害機構2017
- Author(s)
  水島恒裕
- Organizer
  第4回県立健康生活科学研究所・理学部合同研究発表会
- Place of Presentation
  兵庫県立大学 (兵庫県・赤穂郡上郡町)
- Year and Date
  2017-02-10
- Invited
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] Structural Insight into the Molecular Mechanisms of Bacterial Effectors2017
- Author(s)
  Mizushima, T.
- Organizer
  2nd Joint International Symposium of NSRRC, Taiwan, IPR, Osaka University, Japan, Establishment of Structural Biology Network in Asia and Oceania
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] ユビキチン修飾経路の新しい制御メカニズムの解析2017
- Author(s)
  水島恒裕
- Organizer
  さきがけ「生体分子の形と機能」10年間の展開
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] ユビキチン-プロテアソーム経路による生命制御の分子メカニズム2017
- Author(s)
  水島恒裕
- Organizer
  徳島大学薬学部講演会
- Place of Presentation
  徳島大学薬学部 (徳島県・徳島市)
- Year and Date
  2017-03-01
- Invited
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Insight into the Molecular Mechanisms of Bacterial Effectors2017
- Author(s)
  Mizushima, T
- Organizer
  2nd Joint International Symposium of NSRRC, Taiwan, IPR, Osaka University, Japan, Establishment of Structural Biology Network in Asia and Oceania
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 病原細菌エフェクターによる宿主防御経路阻害の分子メカニズム2017
- Author(s)
  水島恒裕
- Organizer
  神戸大学/兵庫県立大学間交流セミナー
- Place of Presentation
  兵庫県立先端科学技術支援センター (兵庫県・赤穂郡上郡町)
- Year and Date
  2017-01-06
- Invited
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] ユビキチン修飾経路の新しい制御メカニズムの解析2017
- Author(s)
  水島恒裕
- Organizer
  さきがけ「生体分子の形と機能」10年間の展開
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 病原細菌エフェクターによる宿主防御経路阻害の分子メカニズム2017
- Author(s)
  水島恒裕
- Organizer
  神戸大学/兵庫県立大学間交流セミナー
- Place of Presentation
  兵庫県立先端科学技術支援センター (兵庫県・赤穂郡上郡町)
- Year and Date
  2017-01-06
- Invited
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] バクテリアの感染戦略：エフェクターによる宿主防御経路の阻害機構2017
- Author(s)
  水島恒裕
- Organizer
  第4回県立健康生活科学研究所・理学部合同研究発表会
- Place of Presentation
  兵庫県立大学 (兵庫県・赤穂郡上郡町)
- Year and Date
  2017-02-10
- Invited
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] ユビキチン-プロテアソーム経路による生命制御の分子メカニズム2017
- Author(s)
  水島恒裕
- Organizer
  徳島大学薬学部講演会
- Place of Presentation
  徳島大学薬学部 (徳島県・徳島市)
- Year and Date
  2017-03-01
- Invited
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] 赤痢菌エフェクター IpaH1880 反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 水島恒裕
- Organizer
  科学研究費補助金　新学術領域「ユビキチンネオバイオロジー」平成28年度　領域班会議
- Place of Presentation
  シャトレーゼガトーキングダムサッポ (北海道・札幌市)
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2016
- Author(s)
  西出旭， Kim Minsoo, 高木賢治, 古田徹郎, 笹川千尋, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 構造学的手法を用いた赤痢菌エフェクター IpaH ファミリーの反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 桑原直之, 加藤龍一, 笹川千尋, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR.2016
- Author(s)
  Takagi, K., Kim, M., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspIによるTRAF6阻害機構の構造生物学解析2016
- Author(s)
  高木賢治, 西出旭, Kim Minsoo, 笹川千尋, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 構造学的手法を用いた赤痢菌エフェクター IpaH ファミリーの反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 桑原直之, 加藤龍一, 笹川千尋, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2016
- Author(s)
  高木賢治, 大津彩織, Kim Minsoo, 水島恒裕
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場 (福岡・福岡市)
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-16K14700
[Presentation] 病原細菌エフェクターによる宿主防御経路阻害の分子メカニズム2016
- Author(s)
  水島恒裕
- Organizer
  神戸大学/兵庫県立大学間交流セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] p62を介したKeap1、LC3複合体状態の解析2016
- Author(s)
  高木賢治, 水島恒裕
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター (宮城県・仙台市)
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2016
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2016
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクター IpaH1880 反応機構の解析2016
- Author(s)
  西出旭, Kim Minsoo, 水島恒裕
- Organizer
  科学研究費補助金　新学術領域「ユビキチンネオバイオロジー」平成28年度　領域班会議
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ (北海道・札幌市)
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] ユビキチンリガーゼによる基質認識と反応機構の構造解析2016
- Author(s)
  水島恒裕
- Organizer
  科学研究費補助金　新学術領域「ユビキチンネオバイオロジー」平成28年度　領域班会議
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ (北海道・札幌市)
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] F-boxタンパク質Ucc1によるクエン酸合成酵素Cit2の認識機構2016
- Author(s)
  西尾和也, 森山周, 中務邦雄, 嘉村巧, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県・横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2016
- Author(s)
  高木賢治, 大津彩織, Kim Minsoo, 水島恒裕
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市)
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR.2016
- Author(s)
  Takagi, K., Kim, M., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクター IpaH1880 反応機構の解析2016
- Author(s)
  西出旭, Minsoo Kim, 水島恒裕
- Organizer
  新学術領域「ユビキチンネオバイオロジー」領域班会議
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural basis for the recognition of phospholylated USP8 by 14-3-3 epsilon2016
- Author(s)
  Nishio, K., Suzuki, E., Komada, M., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo for the School Year of 2015
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2016-03-14
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2016
- Author(s)
  高木賢治, 大津彩織, Kim Minsoo, 水島恒裕
- Organizer
  第16回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 構造学的手法を用いた赤痢菌エフェクター IpaH ファミリーの反応機構の解析2016
- Author(s)
  西出旭, Kim Minsoo, 桑原直之, 加藤龍一, 笹川千尋, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県・横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] クエン酸合成酵素Cit2およびリガンド複合体の結晶構造解析2016
- Author(s)
  森山周, 西尾和也, 中務邦雄, 嘉村巧, 水島恒裕
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜　（神奈川県・横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2016
- Author(s)
  西出旭， Kim Minsoo, 高木賢治, 古田徹郎, 笹川千尋, 水島恒裕
- Organizer
  日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市)
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspIによるTRAF6阻害機構の構造生物学解析2016
- Author(s)
  高木賢治, 西出旭, Kim Minsoo, 笹川千尋, 水島恒裕
- Organizer
  科学研究費補助金　新学術領域「ユビキチンネオバイオロジー」平成28年度　領域班会議
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ (北海道・札幌市)
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2015
- Author(s)
  西出旭，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析2015
- Author(s)
  高木賢治、Kim Minsoo、水島恒裕
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール(徳島・徳島市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターIpaH9.8によるNEMO認識機構の解析2015
- Author(s)
  高木賢治、Kim Minsoo、水島恒裕
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」領域班会議
- Place of Presentation
  南房総富浦ロイヤルホテル（千葉・南房総市）
- Year and Date
  2015-12-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2015
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspIによる免疫阻害機構の解析2015
- Author(s)
  水島恒裕
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白研(大阪・吹田市)
- Year and Date
  2015-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspIによる免疫阻害機構の解析2015
- Author(s)
  水島恒裕
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白研(大阪・吹田市)
- Year and Date
  2015-08-27
- Invited
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspI触媒機構の解明2015
- Author(s)
  西出旭，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural analysis of the recognition mechanism of NEMO by shigella effector IpaH9.82015
- Author(s)
  Otsu, S., Takagi, K., Kim, M., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクタータンパク質IpaH9.8によるNEMOの認識機構の解析2015
- Author(s)
  大津彩織，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクタータンパク質IpaH9.8によるNEMOの認識機構の解析2015
- Author(s)
  大津彩織，高木賢治, Kim Minsoo, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析2015
- Author(s)
  高木賢治、Kim Minsoo、水島恒裕
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール(徳島・徳島市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターによる宿主防御阻害機構の解析2015
- Author(s)
  水島恒裕
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」領域班会議
- Place of Presentation
  南房総富浦ロイヤルホテル（千葉・南房総市）
- Year and Date
  2015-12-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌OpaH1880とIpaH3のMD-SAXS相関構造解析2015
- Author(s)
  浴本亨、西出旭、桑原直之、Kim minsoo、加藤龍一、水島恒裕、池口満徳
- Organizer
  科研費新学術領域研究「ユビキチンネオバイオロジー」領域班会議
- Place of Presentation
  南房総富浦ロイヤルホテル（千葉・南房総市）
- Year and Date
  2015-12-16
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR2015
- Author(s)
  Takagi, K., Kim, M.., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural analysis of the recognition mechanism of phospholylated USP8 by 14-3-3 epsilon2015
- Author(s)
  E. Suzuki, K. Nishio, M. Komada, T. Mizushima
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 14-3-3蛋白質における脱ユビキチン化酵素USP8の機能制御機構の構造基盤2015
- Author(s)
  西尾和也, 鈴木恵利奈, 駒田雅之, 水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  大阪府立大学　（大阪・堺市）
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural analysis of the recognition mechanism of NEMO by shigella effector IpaH9.82015
- Author(s)
  Otsu, S., Takagi, K., Kim, M., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural differences between sugar-recognizing F-box protein Fbs1 and homologous protein FBG32015
- Author(s)
  K. Nishio, Y. Yoshida, K. Tanaka, T. Mizushima
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR2015
- Author(s)
  Takagi, K., Kim, M.., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] Structural Analysis of Reaction Mechanism of Shigella flexneri effector OspI2015
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Sasakawa, C., Mizushima, T.
- Organizer
  3rd International Picobiology Institute Symposium Structural and biological studies on pathogenic and therapeutic targets
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-12-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04341
[Presentation] 赤痢菌エフェクターOspIの結晶構造解析による感染機構の解明2014
- Author(s)
  西出旭、水島恒裕
- Organizer
  兵庫県立大学　知の交流シンポジウム
- Place of Presentation
  姫路商工会議所 (兵庫・姫路市)
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural basis for sugar-recognizing mechanism of ubiquitin ligase SCFFbs12014
- Author(s)
  Nishio K., Yoshida Y., Tanaka K., Mizushima T.
- Organizer
  1st International Picobiology Institute Symposium Picometer- to Micrometer-Level Structural Analyses for Studies on Functional Mechanisms of Proteins
- Place of Presentation
  RIKEN HARIMA　(兵庫県佐用郡)
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターOspIの結晶構造解析による感染機構の解明2014
- Author(s)
  西出旭、水島恒裕
- Organizer
  兵庫県立大学　知の交流シンポジウム
- Place of Presentation
  姫路商工会議所 (兵庫・姫路市)
- Year and Date
  2014-09-24
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI2013
- Author(s)
  Nishide A., Kim M., Takagi K., Himeno A., Sanada T., Sasakawa C., Mizushima T.
- Organizer
  The 35th Naito Conference
- Place of Presentation
  シャトレーゼガトーキングダム（北海道札幌市)
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] ユビキチンリガーゼSCFFbs1の糖鎖認識機構の構造基盤2013
- Author(s)
  西尾和也、吉田雪子、田中啓二、水島恒裕
- Organizer
  日本結晶学会年会
- Place of Presentation
  熊本大学(熊本県熊本市)
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] OspI-Ubc13複合体構造解析による赤痢菌エフェクタータンパク質のE2酵素認識機構2013
- Author(s)
  西出旭、Minsoo Kim、高木賢治、真田貴人、笹川千尋、水島恒裕
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館 (鳥取)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] OspI-Ubc13複合体構造解析による赤痢菌エフェクタータンパク質のE2酵素認識機構2013
- Author(s)
  西出旭、Minsoo Kim、高木賢治、真田貴人、笹川千尋、水島恒裕
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館(鳥取県鳥取市)
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 脱アミド化Ubc13の構造解析による赤痢菌感染機構の考察2013
- Author(s)
  高木賢治　西出旭、Kim Minsoo、笹川千尋、水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural basis for the recognition of Ubc13 by the Shigella flexneri effector OspI2013
- Author(s)
  Nishide A., Kim M., Takagi K., Himeno A., Sanada T., Sasakawa C., Mizushima T.
- Organizer
  The 35th Naito Conference
- Place of Presentation
  ｼｬﾄﾚｰｾﾞｶﾞﾄｰｷﾝｸﾞﾀﾞﾑ(北海道)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクタータンパク質OspI-Ubc13複合体結晶構造解析による機能解析2013
- Author(s)
  西出旭,Minsoo Kim,高木賢治,真田真人,笹川千尋,水島恒裕
- Organizer
  新学術領域『ユビキチンネオバイオロジー』第2回領域会議
- Place of Presentation
  熱海ﾆｭｰﾌｼﾞﾔﾎﾃﾙ (静岡)
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] プロテアソーム複合体構造とシャペロンによる形成機構2012
- Author(s)
  水島恒裕
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)(招待講演)
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] プロテアソーム19S制御因子複合体形成シャペロンHsm3の構造解析2012
- Author(s)
  高木賢治、金相佑、加藤晃一、田中啓二、佐伯泰、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] プロテアソーム複合体構造とシャペロンによる形成機構2012
- Author(s)
  水島恒裕
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] プロテアソーム19S 制御因子複合体形成シャペロンHsm3 の構造解析2012
- Author(s)
  高木賢治、金相佑、加藤晃一、田中啓二、佐伯泰、水島恒裕
- Organizer
  第12回　日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] Studies of the structure and molecular mechanisms of the proteasome assembly2012
- Author(s)
  Tsunehiro Mizushima
- Organizer
  The Annual Review Conference of the Global COE program of University of Hyogo
- Place of Presentation
  兵庫県立先端科学技術支援センター (兵庫)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] 赤痢菌エフェクタータンパク質OspI 活性中心の構造解析2012
- Author(s)
  西出旭、高木賢治、Minsoo Kim、真田貴人、笹川千尋、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Studies of the structure and molecular mechanisms of the proteasome assembly2012
- Author(s)
  Tsunehiro Mizushima
- Organizer
  The Annual Review Conference of the Global COE program of University of Hyogo
- Place of Presentation
  Center for Advanced Science & Technology HYOGO (Hyogo, Japan)
- Year and Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] Studies of the structure and molecular mechanisms of the proteasome a ssembly2012
- Author(s)
  Tsunehiro Mizushima
- Organizer
  The Annual Review Conference of the Global COE program of University of Hyogo
- Place of Presentation
  兵庫県立先端科学技術支援センター(兵庫)
- Year and Date
  2012-02-13
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] 赤痢菌エフェクタータンパク質OspI活性中心の構造解析2012
- Author(s)
  西出旭、高木賢治、Minsoo Kim、真田貴人、笹川千尋、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] プロテアソーム19S制御因子複合体形成シャペロンHsm3の構造解析2012
- Author(s)
  高木賢治、金相佑、加藤晃一、田中啓二、佐伯泰、水島恒裕
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(愛知)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] プロテアソーム複合体構造とシャペロンによる形成機構2012
- Author(s)
  水島恒裕
- Organizer
  第85回　日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Invited
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] プロテアソーム複合体構造とシャペロンによる形成機構2012
- Author(s)
  水島恒裕
- Organizer
  第85回　日本生化学会大会
- Place of Presentation
  福岡国際会議場(福岡)
- Invited
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] ユビキチン-プロテアソーム経路による特異的なタンパク質分解機構2011
- Author(s)
  水島恒裕
- Organizer
  グローバルCOEプログラム生命科学若手研究者発表会
- Place of Presentation
  兵庫県立先端科学技術支援センター(兵庫)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] 19S制御因子の複合体形成を介助するシャペロン分子の機能と構造2011
- Author(s)
  廣本武史、水島恒裕、金相佑、矢木真穂、大川慶祐、佐伯泰、田中啓二、加藤晃一
- Organizer
  ターゲットタンパク研究プログラム平成22年度公開シンポジウム
- Place of Presentation
  東京大学(東京)
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] プロテアソーム分子集合シャペロンRpn14 E384A変異体の結晶構造解析2011
- Author(s)
  水島恒裕、金相佑、西出旭、佐伯泰、田中啓二、加藤晃一
- Organizer
  平成23年度日本結晶学会年会
- Place of Presentation
  北海道大学学術交流会館 (北海道)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] ユビキチン-プロテアソーム経路による特異的なタンパク質分解機構2011
- Author(s)
  水島恒裕
- Organizer
  グローバルCOEプログラム生命科学若手研究者発表会
- Place of Presentation
  兵庫県立先端科学技術支援センター(兵庫)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] 不要なタンパク質を分解する装置の構造2011
- Author(s)
  水島恒裕
- Organizer
  第4回兵庫県立大学シンポジウム
- Place of Presentation
  神戸市産業振興センター(兵庫)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] A systematic approach to structural glycobiology2011
- Author(s)
  K.Kato, H.Yagi, Y.Kamiya, M.Nishio, T.Yamaguchi, S.Yamamoto, M.Yagi-Utsumi, T.Mizushima
- Organizer
  Third Korea-Japan Seminar on Biomolecular Sciences-Experiments and Simulations
- Place of Presentation
  ロッテホテルJeju(韓国)
- Year and Date
  2011-02-27
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] プロテアソーム19S複合体の分子集合を支援する新規シャペロンHsm3の構造とメカニズム2011
- Author(s)
  高木賢治、金相佑、佐伯泰、田中啓二、加藤晃一、水島恒裕
- Organizer
  平成23年度日本結晶学会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] ユビキチン-プロテアソーム経路による特異的なタンパク質分解機構2011
- Author(s)
  水島恒裕
- Organizer
  グローバルCOEプログラム生命科学若手研究者発表会
- Place of Presentation
  兵庫県立先端科学技術支援センター (兵庫)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] プロテアソーム分子集合シャペロンRpn14 E384A変異体の結晶構造解析2011
- Author(s)
  水島恒裕、金相佑、西出旭、佐伯泰、田中啓二、加藤晃一
- Organizer
  平成23年度日本結晶学会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] プロテアソーム19S制御複合体の分子集合を支援する新規シャペロンHsm3の構造とメカニズム2011
- Author(s)
  高木賢治、金相佑、佐伯泰、田中啓二、加藤晃一、水島恒裕
- Organizer
  平成23年度日本結晶学会年会
- Place of Presentation
  北海道大学学術交流会館 (北海道)
- Data Source
  KAKENHI-PROJECT-23657080
[Presentation] プロテアソーム19S制御複合体の分子集合を支援する新規シャペロンHsm3の構造とメカニズム2011
- Author(s)
  高木賢治、金相佑、佐伯泰、田中啓二、加藤晃一、水島恒裕
- Organizer
  平成23年度日本結晶学会年会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] プロテアソーム分子集合シャペロンRpn14 E384A変異体の結晶構造解析2011
- Author(s)
  水島恒裕、金相佑、西出旭、佐伯泰、田中啓二、加藤晃一
- Organizer
  平成23年度日本結晶学会年会
- Place of Presentation
  北海道大学学術交流会館(北海道)
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] 不要なタンパク質を分解する装置の構造2011
- Author(s)
  水島恒裕
- Organizer
  第4回兵庫県立大学シンポジウム
- Place of Presentation
  神戸市産業振興センター(兵庫)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PUBLICLY-23121525
[Presentation] A systematic approach to structural glycobiology2011
- Author(s)
  K. Kato, H. Yagi, Y. Kamiya, M. Nishio, T. Yamaguchi, S. Yamamoto, M. Yagi-Utsumi and T. Mizushima
- Organizer
  3rd Korea-Japan Seminar on Biomolecular Sciences-Experiments and Simulations
- Place of Presentation
  LOTTE Hotel(Jeju, Korea)
- Year and Date
  2011-02-27
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] プロテアソームの構造生物学2010
- Author(s)
  水島恒裕、加藤晃一、森本幸生、田中啓二
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会 (BMB2010)
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] Structural views of the ubiquitin-proteasome system2010
- Author(s)
  K. Kato and T. Mizushima
- Organizer
  The 2010 International Chemical Congress of Pacific Basin Societies(PACIFICHEM 2010)
- Place of Presentation
  ハワイコンベンションセンター(Honolulu, U. S. A.)
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] レクチンとカルシウム結合タンパク質の複合体形成による血液凝固因子の細胞内輸送メカニズム2010
- Author(s)
  西尾美穂, 神谷由紀子, 水島恒裕, 矢木真穂, 若槻壮市, 笹川拡明, 山本一夫, 加藤晃一
- Organizer
  糖鎖科学名古屋拠点第8回「若手のカフォーラム」
- Place of Presentation
  名古屋大学・VBLホール(愛知)
- Year and Date
  2010-09-06
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] レクチンとEFバンドタンパク質の協働的相互作用による血液凝固因子の細胞内輸送の構造基盤2010
- Author(s)
  西尾美穂, 神谷由紀子, 水島恒裕, 若槻壮市, 笹川拡明, 山本一夫, 内山進, 野田勝紀, McKay Adam R, 福井希一, Hauri Hans-Peter, 加藤晃一
- Organizer
  第10回日本蛋白質科学会年会
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] Crystal structure of Hsm3p, an assembly chaperone of the 19S regulatory particle of the proteasome2010
- Author(s)
  Sangwoo Kim, Tsunehiro Mizushima, Yasushi Saeki, Keiji Tanaka, Koichi Kato
- Organizer
  The 10^<th> Conference of the Asian Crystallographic Association
- Place of Presentation
  Busan, Korea
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] Structural views of the ubiquitin-proteasome system2010
- Author(s)
  K.Kato, T.Mizushima
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  ハワイコンベンションセンターHonolulu(LT.S.A.)
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] タンパク質分解酵素複合体プロテアソームの構造と複合体形成機構2010
- Author(s)
  水島恒裕
- Organizer
  兵庫県立大学理学部セミナー
- Place of Presentation
  兵庫県立大学(兵庫)
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] コビキチンリガーゼによる糖タンパク質品質管理における糖鎖認識機構の解析2009
- Author(s)
  水島恒裕、熊埜御堂太一、鈴木淳巨、山根隆、加藤晃
- Organizer
  糖鎖科学名古屋拠点第7回「若手の力」フォーラムおよび拠点共同研究報告会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] プロテアソーム制御因子複合体形成シャペロンのX線結晶構造解析2009
- Author(s)
  水島恒裕、金相佑、佐伯泰、田中啓二、加藤晃一
- Organizer
  特定領域研究超分子構造第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] Structural basis of the molecular recognition by ERGIC-53 involved in the glycoprotein traffic in the cell2009
- Author(s)
  Yukiko Kamiya, Miho Nishio, Tsunehiro Mizushima, Soichi Wakatsuki, Kazuo Yamamoto, Susumu Uchiyama, Masanori Noda, Hans-Peter Hauri, Koichi Kato
- Organizer
  20th International Symposium on Glycoconjugates
- Place of Presentation
  Caribe Hilton(Puerto Rico)
- Year and Date
  2009-11-30
- Data Source
  KAKENHI-PROJECT-21370050
[Presentation] 鎖認識ユビキチンリガーゼFbsファミリーの構造と反応機構2009
- Author(s)
  水島恒裕
- Organizer
  第4回プロテオミクス・構造生物学講演会
- Place of Presentation
  岡崎
- Year and Date
  2009-01-30
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] 鎖認識ユビキチンリガーゼFbsファミリーの構造と反応機構2009
- Author(s)
  水島恒裕
- Organizer
  第4回プロテオミクス・構造生物学講演会
- Place of Presentation
  岡崎
- Year and Date
  2009-01-30
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] プロテアソーム制御因子複合体形成シャペロンのX線結晶構造解析2009
- Author(s)
  水島恒裕、金相佑、佐伯泰、田中啓二、加藤晃一
- Organizer
  特定領域研究超分子構造第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] プロテアソーム制御因子複合体形成シャペロンのX線結晶構造解析2009
- Author(s)
  水島恒裕、金相佑、佐伯泰、田中啓二、加藤晃一
- Organizer
  特定領域研究超分子構造第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] 鎖認識ユビキチンリガーゼFbsファミリーの構造と反応機構2009
- Author(s)
  水島恒裕
- Organizer
  第4回プロテオミクス・構造生物学講演会
- Place of Presentation
  岡崎
- Year and Date
  2009-01-30
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] プロテアソーム制御因子複合体形成シャペロンのX線結晶構造解析2009
- Author(s)
  水島恒裕、金相佑、佐伯泰、田中啓二、加藤晃一
- Organizer
  特定領域研究超分子構造第6回公開シンポジウム
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] ユビキチンリガーゼによる糖タンパク質品質管理における糖鎖認識機構の解析2009
- Author(s)
  水島恒裕、熊埜御堂太一、鈴木淳巨、山根隆、加藤晃一
- Organizer
  糖鎖科学名古屋拠点第7回「若手の力」フォーラムおよび拠点共同研究報告会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] ユビキチンリガーゼによる糖タンパク質品質管理における糖鎖認識機構の解析2009
- Author(s)
  水島恒裕、熊埜御堂太一、鈴木淳巨、山根隆、加藤晃
- Organizer
  糖鎖科学名古屋拠点第7回「若手の力」フォーラムおよび拠点共同研究報告会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PUBLICLY-21025027
[Presentation] プロテアソームシャペロンDmp1-Dmp2複合体による20Sプロテアソーム分子集合機構2008
- Author(s)
  水島恒裕、八代田英樹、田中啓二
- Organizer
  日本蛋白質科学会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] プロテアソームシャペロンDmp1-Dmp2複合体による20Sプロテアソーム分子集合機構2008
- Author(s)
  水島恒裕、八代田英樹、田中啓二
- Organizer
  日本蛋白質科学会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] X-ray Structure of the Skp1-Fbs1 glycoprotein complex2008
- Author(s)
  T. Mizushima, Y. Yoshida, T. Kumanomidou, Y. Hasegawa, A. Suzuki, T. Yamane, K. Tanaka
- Organizer
  FEBS Congress & IUBMB Conference
- Place of Presentation
  Athens, Greece
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] STRUCTURE BASIS FOR RECOGNITION OF GLYCOSYLAT ED SUBSTRATES BY SCFFbsi UBIQUITIN LIGASE2008
- Author(s)
  T. Mizushima, Y. Yoshida, T. Kumanomidou, Y. Yamaguchi, T. Yamane, K. Tanaka, K. Kato
- Organizer
  ZOMES V
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] 酵母20Sプロテアソーム構造形成に関与するシャペロンDmp1-Dmp2の役割2008
- Author(s)
  水島恒裕、高木賢治、八代田英樹、栗本英治、田中啓二、加藤晃一
- Organizer
  特定領域研究「生体超分子構造」第5回公開シンポジウム
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] X-ray Structure of the Skp1-Fbs1 glycoprotein complex2008
- Author(s)
  Mizushima T., Yoshida Y., Kumanomidou T., Hasegawa Y., Suzuki A., Yamane T., Tanaka K.
- Organizer
  FEBS Congress & IUBMB Conference
- Place of Presentation
  Athens, Greece
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] X-ray Structure of the Skpl-Fbsi glycoprotein complex2008
- Author(s)
  T. Mizushima, Y. Yoshida, T. Kumanomidou, Y. Hasegawa, A. Suzuki, T. Yamane, K. Tanaka
- Organizer
  FEBS Congress & IUBMB Conference
- Place of Presentation
  Athens, Greece
- Year and Date
  2008-06-30
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] プロテアソームシャペロンDmp1-Dmp2複合体による20Sプロテァソーム分子集合機構2008
- Author(s)
  水島恒裕、八代田英樹、田中啓二
- Organizer
  日本蛋白質科学会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] STRUCTURE BASIS FOR RECOGNITION OF GLYCOSYLATED SUBSTRATES BY SCFFbs1 UBIQUITIN LIGASE2008
- Author(s)
  Mizushima T., Yoshida Y., Kumanomidou T., Yamaguchi Y., Yamane T., Tanaka K., Kato K.
- Organizer
  ZOMES V
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] STRUCTURE BASIS FOR RECOGNITION OF GLYCOSYLAT ED SUBSTRATES BY SCFFbs1 UBIQUITIN LIGASE2008
- Author(s)
  T. Mizushima, Y. Yoshida, T. Kumanomidou, Y. Yamaguchi, T. Yamane, K. Tanaka, K. Kato
- Organizer
  ZOMES V
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] プロテアソームシャペロンDmp1-Dmp2複合体による20Sプロテアソーム分子集合機構2008
- Author(s)
  水島恒裕、八代田英樹、田中啓二
- Organizer
  日本蛋白質科学会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20051010
[Presentation] SCF^<Fbs1>ユビキチンリガーゼによる糖蛋白の選択的認識機構2007
- Author(s)
  水島恒裕、吉田雪子、熊埜御堂太一、田中啓二、山根隆
- Organizer
  日本蛋白質科学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-18054011
[Presentation] SCFFbs1ユビキチンリガーゼによる糖蛋白の選択的認識機構2007
- Author(s)
  水島恒裕、吉田雪子、熊埜御堂太一、田中啓二、山根隆
- Organizer
  日本蛋白質科学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] X-ray Structure of the Skp1-Fbs1 glycoprotein complex2007
- Author(s)
  Tsunehiro Mizushima, Yukiko Yoshida, Taichi Kumanomidou, Yuko Hasegawa, Atsuo Suzuki, Takashi Yamane, Keiji Tanaka
- Organizer
  ASCA2007
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] X-ray Structure of the Skp1-Fbs1 glycoprotein complex2007
- Author(s)
  Mizushima T, Yoshida Y, Kumanomidou T, Hasegawa Y, Suzuki A, Yamane T, Tanaka K
- Organizer
  ASCA2007
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] SCF^<Fbs1>ユビキチンリガーゼによる糖蛋白の選択的認識機構2007
- Author(s)
  水島恒裕、吉田雪子、熊埜御堂太一、田中啓二、山根隆
- Organizer
  日本蛋白質科学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19770080
[Presentation] X-ray Structure of the Skp1-Fbs1 glycoprotein complex2007
- Author(s)
  Tsunehiro Mizushima, Yukiko Yoshida, Taichi Kumanomidou, Yuko Hasegawa, Atsuo Suzuki, Takashi Yamane, Keiji Tanaka
- Organizer
  ASCA2007
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-18054011
[Presentation] SCF^<Fbs1>ユビキチンリガーゼによる糖蛋白の選択的認識機構2007
- Author(s)
  水島恒裕、吉田雪子、熊埜御堂太-、田中啓二、山根隆
- Organizer
  日本蛋白質科学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19044018
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのX線結晶構造解析
- Author(s)
  高木賢治、Kim Minsoo、笹川千尋、水島恒裕
- Organizer
  新学術領域研究「ユビキチンネオバイオロジー」平成26年度領域班会議
- Place of Presentation
  ホテルたつき（愛知・蒲郡市）
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析
- Author(s)
  高木賢治、水島恒裕
- Organizer
  日本結晶学会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR
- Author(s)
  Takagi, K., Nishide, A., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural analyses of bacterial effectors and their mechanisms of infection in the ubiquitin-proteasome system
- Author(s)
  Mizushima T.
- Organizer
  2nd International Picobiology Institute Symposium Development & Destruction
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2014-10-09 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] Structural basis for the formation of sugar-recognizing site of ubiquitin ligase SCFFbs1
- Author(s)
  Nishio, K. Yoshida, Y. Tanaka, K. Mizushima T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structure and substrate recognition mechanism of IpaH9.8 LRR
- Author(s)
  Takagi, K., Nishide, A., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research
- Place of Presentation
  国際高等研究所（京都・木津川市）
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI
- Author(s)
  Nishide, A., Kim, M., Takagi, K., Himeno, A., Sanada, T., Sasakawa, C., Mizushima, T.
- Organizer
  The Annual Evaluation Conference of the Leading Program, University of Hyogo
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2015-03-16 – 2015-03-17
- Data Source
  KAKENHI-PROJECT-24370049
[Presentation] 赤痢菌エフェクターIpaH9.8基質認識ドメインのＸ線結晶構造解析
- Author(s)
  高木賢治、水島恒裕
- Organizer
  日本結晶学会
- Place of Presentation
  東京大学(東京)
- Year and Date
  2014-11-01 – 2014-11-03
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural basis for sugar-recognizing mechanism of ubiquitin ligase SCFFbs1
- Author(s)
  Nishio, K. Yoshida, Y. Tanaka, K. Mizushima T.
- Organizer
  2nd International Picobiology Institute Symposium Development & Destruction
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] 赤痢菌エフェクターＩｐaＨ１８８０の結晶化と構造解析
- Author(s)
  西出旭、ＫｉｍＭｉｎｓｏｏ、笹川千尋、水島恒裕
- Organizer
  新学術領域研究「ユビキチンネオバイオロジー」平成26年度領域班会議
- Place of Presentation
  ホテルたつき（愛知・蒲郡市）
- Year and Date
  2014-12-03 – 2014-12-05
- Data Source
  KAKENHI-PLANNED-24112009
[Presentation] Structural analyses of bacterial effectors and their mechanisms of infection in the ubiquitin-proteasome system
- Author(s)
  Mizushima T.
- Organizer
  2nd International Picobiology Institute Symposium Development & Destruction
- Place of Presentation
  先端科学技術支援センター (兵庫・赤穂郡上郡町)
- Year and Date
  2014-10-09 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PLANNED-24112009

1. KIM Minsoo (50466835)

# of Collaborated Projects: 5 results

# of Collaborated Products: 32 results
2. KATO Koichi (20211849)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
3. 谷一寿 (20541204)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. YAMAGUCHI Takumi (60522430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KAMIYA Yukiko (00527947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. SATO Tadashi (80532100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SANADA Takahito (00569957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAGI Hirokazu (70565423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Tezuka Tohru (50312319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山口芳樹 (90323451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 栗本英治 (90234575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 加藤龍一 (50240833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 山吉麻子 (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. S Youssefian (00210576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KUWABARA Naoyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. TAKAGI Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
17. KOBAYASHI Hatasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. TAGUCHI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 木村洋子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 岩井一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 小泉昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizushima Tsunehiro 水島 恒裕

MIZUSHIMA Tsunehiro 水島 恒裕

Research Projects

Research Products

Co-Researchers

ユビキチンリガーゼが制御する病原菌感染と生体防御応答の構造生物学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New antibiotics development

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural studies of infection mechanisms targeting the NF-kB pathway by pathogenic bacterial effectorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of heritable risk factors for moyamoya disease and stroke

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural and functional analyses of bacterial ubiquitin ligasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural biology of Shigella effectors to elucidate the molecular mechanisms of substrate recognition and infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural studies for specific recognition of ubiquitin signalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analyses of bacterial effectors and their mechanisms of infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

26Sプロテアソーム複合体構造解析による超分子作動機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vitro reconstitution of eukaryotic proteasomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A bacterial effector deamidates UBC13 to dampen the inflammatory response

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

20Sプロテアソーム複合体構築に関与するシャペロン蛋白質の構造及び作用機構解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of structural basis for molecular recognition and supramolecular complex formation of intracellular lectins involved in post-endoplasmic reticulum quality control

Principal Investigator

Project Period (FY)

Mizushima Tsunehiro 水島恒裕

MIZUSHIMA Tsunehiro 水島恒裕

[Book] 実験医学増刊号タンパク質の分解機構 (SCF^<Fbs1>の構造と機能分担執筆)2008

[Book] 実験医学増刊号タンパク質の分解機構(SCF^<Fbs1>の構造と機能分担執筆)2008

[Book] 実験医学増刊号タンパク質の分解機構 (SCF^<Fbs1>の構造と機能分担執筆)2008