WATANABE Hisayoshi 渡辺久剛

Researcher Number	00332536
Affiliation (based on the past Project Information) *help	2015: 山形大学, 医学部, 非常勤講師 2012 – 2014: 山形大学, 医学部, 講師 2010: 山形大学, 医学部, 講師 2008 – 2009: Yamagata University, 医学部, 助教 2004: 山形大, 医学部, 助手 2001 – 2004: 山形大学, 医学部, 助手 2002: 山形大学, 医学部・内科学第二講座, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / Hygiene
Keywords	Principal Investigator HCV / 感染培養系 / メタボローム解析 / 感染 / 細胞内代謝 / メタボローム / C型肝炎 / 中和抗体 / ワクチン / SLC7A7 … More / NOドナー / リジン尿性蛋白不耐症 / 門脈循環 / NO / L-アルギニン / 分子生物学 / 遺伝子変異 / X遺伝子 / B型肝炎ウイルス … More Except Principal Investigator oval cell / ALDH2 / ADH / Matrigel / Notch signal / Musashi-1 gene / oval cells / 肝幹細胞 / 肝がん / C型肝炎 / Single nucleotide polymorphism / Hepatocullular carcinoma / Hepatitis C / ADH2 / 遺伝子多型 / GFP transgenic mice / bone marrow cells / Hepatic stem cells / Liver regeneration / natchシグナル / Musashi-1遺伝子 / oval cell line / GFPトランスジェニック・マウス / Musashi-1 / GFPトランスジェニックマウス / 骨髄細胞 / Musashi-1遺伝 / 肝再生 / angiotensin II / Angiotensin II receptor / chronic hepatitis C / hepatic cirrhosis / Hepatic fibrosis / アンギオテンシン受容体 / アンギオテンシン / アンギオテンシンII受容体 / アンギオテンシンII / 受容体阻害薬 / アンギオテンジンII受容体 / アンギオテンジンII / C型慢性肝炎 / 肝硬変 / 肝線維化 / Hepatoma cell lines / hepatocytes / Hepatic Stem cell / 肝細胞 / 肝癌細胞株 / 幹細胞 / Musashi遺伝子 / 診断マーカー / 分子標的治療 / microRNA / 肝癌 / RHAi / 脂質代謝 / 自然免疫 / HCV replicon / RNAi / C型肝炎ウイルス Less

Metabolomic profile of hepatitis C virus-infected hepatocytesPrincipal Investigator
- Principal Investigator
  
  Watanabe Hisayoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
A translational research on miR-224: towards novel diagnostic and therapeutic approach for hepatocellular carcinoma
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
RNA interference screen for host factors required for HCV replication
- Principal Investigator
  
  SHO Ri
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Mechanism of Neutralization using Infectious Hepatitis C Chimeric VirusesPrincipal Investigator
- Principal Investigator
  
  WATANABE Hisayoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
新しい肝病態、アルギニントランスポーター欠損症における門脈循環障害の分子機構解明Principal Investigator
- Principal Investigator
  
  渡辺久剛
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Development of liver regeneration therapy against severe hepatic failure based on stem cell science -Differentiation and growth of hepatic stem cell and cell transplantation.
- Principal Investigator
  
  KAWATA Sumio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Interaction of alcohol consumption and a single nucleotide polymorphism in aldehyde dehydrogenase 2 (ALDH2) on the susceptibility to hepatocellular carcinoma in Japanese patients with hepatitis C
- Principal Investigator
  
  LI Shao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Yamagata University
B型肝炎ウイルス変異株におけるウイルス蛋白発現抑制に関する研究Principal Investigator
- Principal Investigator
  
  渡辺久剛
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Development of strategic therapy for severe hepatic failure using regenerative medicine-Isolation of hepatic stem cell expressing musashi-1 gene and cell therapy
- Principal Investigator
  
  KAWATA Sumio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University
Development of hepatic anti-fibrotic therapy targeted to angiotensin II receptor antagonist-soppression of collagen production in the Ito cell via TGF-β
- Principal Investigator
  
  KAWATA Sumio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yamagata University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2004 Other

All Journal Article Presentation Book

[Book] 厚生労働省科学研究費補助金（肝炎等克服緊急対策事業）平成26年度総括・分担研究報告書「C型肝炎の新規診断法や新規治療法を開発するためのゲノムワイド関連解析の手法を用いた宿主因子の解析に関する研究」2015
- Author(s)
  渡辺久剛
- Total Pages
  120
- Publisher
  住民/患者コホートにおける病態進展に関わる遺伝因子の探索
- Data Source
  KAKENHI-PROJECT-25460974
[Book] 日本臨床増刊号「新ウイルス性肝炎学」2015
- Author(s)
  渡辺久剛、上野義之
- Total Pages
  704
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-25460974
[Book] 消化器内科2014
- Author(s)
  渡辺久剛、斎藤貴史、水野　恵、勝見智大、冨田恭子、佐藤智佳子、奥本和夫、西瀬雄子、上野義之
- Total Pages
  276
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-25460974
[Book] Hepatology Practice 「C型肝炎の診療を極める」2014
- Author(s)
  渡辺久剛、上野義之
- Total Pages
  332
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25460974
[Book] 肝胆膵2013
- Author(s)
  渡辺久剛、上野義之
- Total Pages
  564
- Publisher
  アークメディカル
- Data Source
  KAKENHI-PROJECT-25460974
[Book] メディカルレビュー2013
- Author(s)
  渡辺久剛、斎藤貴史、石橋正道、新澤陽英、河田純男
- Total Pages
  175
- Publisher
  コホート研究からみたウイルス性肝炎の解明
- Data Source
  KAKENHI-PROJECT-25460974
[Book] ハリソン内科学第4版2013
- Author(s)
  渡辺久剛、冨田恭子、河田純男
- Total Pages
  3120
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-25460974
[Book] HCVコホート研究による持続感染者の自然経過.HCV感染のnatural courseを探る:わが国におけるコホート研究(河田純男監修、佐田通夫・新沢陽英・斎藤貴史編)2011
- Author(s)
  渡辺久剛, 斎藤貴史, 西瀬雄子, 邵力, 佐藤智佳子, 石井里佳, 芳賀弘明, 奥本和夫, 斎藤孝治, 冨樫整, 新沢陽英, 河田純男
- Publisher
  山形大学出版
- Data Source
  KAKENHI-PROJECT-20590757
[Book] HCVコホート研究による持続感染者の自然経過.HCV感染のnatural courseを探る:わが国におけるコホート研究(河田純男監修、佐田通夫・新沢陽英・斎藤貴史編)2011
- Author(s)
  渡辺久剛, ほか
- Publisher
  山形大学出版
- Data Source
  KAKENHI-PROJECT-20590757
[Book] 分子標的薬治療における消化器症状対策.分子標的薬トータルマネージメントYURCCパッケージver.1.2(冨田善彦編)2010
- Author(s)
  渡辺久剛
- Publisher
  リッチヒルメディカル
- Data Source
  KAKENHI-PROJECT-20590757
[Book] HCV感染のnatural courseを探る:わが国におけるコホート研究2010
- Author(s)
  渡辺久剛, 齋藤貴史, 邵力等
- Publisher
  山形大学出版社
- Data Source
  KAKENHI-PROJECT-20590756
[Book] HCVキャリアからのHCV RNA自然消失はあるのか?肝臓病診療こんなときどうするQ & A(河田純男、佐々木裕編)2009
- Author(s)
  渡辺久剛, 河田純男
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590757
[Book] PegIFN+リバビリン療法の治療効果はウイルス学的にどこまで予測できるか?肝臓病診療こんなときどうするQ & A(河田純男、佐々木裕編)2009
- Author(s)
  齋藤貴史, 渡辺久剛, 河田純男
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590757
[Book] 慢性肝炎.ハリソン内科学第3版(福井次矢、黒川清編)2009
- Author(s)
  渡辺久剛, 河田純男
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-20590757
[Book] 当科における肝硬変の成因別実態.肝硬変の成因別実態(青柳豊、他編)2008
- Author(s)
  宇賀神智, 奥本和夫, 斎藤貴史, 佐藤智佳子, 芳賀弘明, 石井里佳, 鈴木明彦, 三條麻衣, 西瀬雄子, 伊藤純一, 菅原一彦, 渡辺久剛, 斎藤孝治, 冨樫整, 河田純男
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590757
[Book] 肝硬変.肝臓病のすべて(与芝真彰編)2008
- Author(s)
  渡辺久剛, 河田純男
- Publisher
  日本評論社
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] A thymine-adenine dinucleotide repeat polymorphism near IL28B is associated with spontaneous clearance of hepatitis C virus.2015
- Author(s)
  Hiramine S, Sugiyama M, Furusyo N, Uto H, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K, Masaki N, Hayashi J, Thomas DL, Mizokami M
- Journal Title
  
  J Gastroenterol
  
  Volume: 51 Pages: 1069-1077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] 脾摘6か月後に食道静脈瘤出血を来たした胆道閉鎖症術後の1小児例.2014
- Author(s)
  奥本和夫、水野　恵、勝見智大、冨田恭子、佐藤智佳子、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Journal Title
  
  日本門脈圧亢進症学会雑誌
  
  Volume: 20 Pages: 142-146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] ジェノタイプの感染実態の変遷とB型肝炎キャリアおよび急性肝炎例におけるジェノタイプの臨床的意義2014
- Author(s)
  渡辺久剛、斎藤貴史、水野　恵、勝見智大、冨田恭子、佐藤智佳子、奥本和夫、西瀬雄子、上野義之
- Journal Title
  
  消化器内科
  
  Volume: 58 Pages: 213-219
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.2014
- Author(s)
  Tomita K, Haga H, Mizuno K, Katsumi T, Sato C, Okumoto K, Nishise Y, Watanabe H, Saito T, Ueno Y
- Journal Title
  
  Am J Phisiol Gastrointest Liver Physiol
  
  Volume: 307 Issue: 1 Pages: G50-G57
- DOI
  10.1152/ajpgi.00434.2013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] アポ型ALTによりALTが異常低値を示したC型慢性肝炎に対して抗ウイルス療法を行った一例.2013
- Author(s)
  奥本和夫、斎藤貴史、勝見智大、冨田恭子、佐藤智佳子、阿蘇里佳、西瀬雄子、渡辺久剛、上野義之
- Journal Title
  
  肝臓
  
  Volume: 54 Pages: 543-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] Serum prolactin levels and prolactin mRNA expression in peripheral blood mononuclear cells in hepatitis C vrus infection.2013
- Author(s)
  Ishii R, Saito T, Shao L, Okumoto K, Nishise Y, Watanabe H, Makino N, Fukao A, Kitanaka C, Kayama T, Ueno Y, Kawata S.
- Journal Title
  
  J Med Virol
  
  Volume: 85 Pages: 1199-1205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] Impaired mitochondrial ß-oxidation in patients with chronic hepatitis C: relation with viral load and insulin resistance.2013
- Author(s)
  Sato C, Saito T, Shao L, Okumoto K, Nishise Y, Watanabe H, Makino N, Fukao A, Kitanaka C, Kayama T, Ueno Y, Kawata S.
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 13 Pages: 112-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] Dynamics of serum metabolites in patients with chronic hepatitis C receiving pegylated interferon plus ribavirin: A metabolomics analysis.2013
- Author(s)
  Saito T, Sugimoto M, Igarashi K, Saito K, Shao L, Katsumi T, Tomita K, Sato C, Okumoto K, Nishise Y, Watanabe H, Tomita M, Ueno Y, Soga T.
- Journal Title
  
  Metabolism
  
  Volume: 62 Pages: 1577-1586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] A case of adult type 1 Gaucher disease complicated by temporal intestinal hemorrhage.2013
- Author(s)
  Ito J, Saito T, Numakura C, Iwaba A, Sugahara S, Ishii R, Sato C, Haga H, Okumoto K, Nishise Y, Watanabe H, Ida H, Hayasaka K, Togashi H, Kawata S, Ueno Y.
- Journal Title
  
  Case Rep Gastroenterol
  
  Volume: 7 Pages: 340-346
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460974
[Journal Article] (99m) Tc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C2011
- Author(s)
  Ishii R, Togashi H, Iwaba A, Sato C, Haga H, Sanjo M, Okumoto K, Nishise Y, Ito JI, Watanabe H, Saito K, Okada A, Takahashi K, Saito T, Kawata S
- Journal Title
  
  Ann Nucl Med
  
  Pages: 520-523
- NAID
  10029525687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Serum metabolomics reveals γ-glutamyl dispeptides as biomarkers for discrimination among different forms of liver disease2011
- Author(s)
  Soga T, Sugimoto M, Honma M, Mori M, Igarashi K, Kashikura K, Ikeda S, Hirayama A, Yamamoto T, Yoshida H, Otsuka M, Tsuji S, Yatomi Y, Sakuragawa T, Watanabe H, Nihei K, Saito T, Kawata S, Suzuki H, Tomita M, Suematsu M
- Journal Title
  
  J Hepatol
  
  Pages: 896-965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Sequence heterogeneity of NS5A and core proteins of hepatitis C virus and virological responses to pegylated-interferon/ribavirin combination therapy2011
- Author(s)
  El-Shamy A, Shoji I, Saito T, Watanabe H, Ide YH, Deng L, Kawata S, Hotta H
- Journal Title
  
  Microbiol Immunol
  
  Pages: 418-426
- NAID
  10031121486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Potential therapeutic application of intravenous autologous bone marrow infusion in patients with alcoholic liver cirrhosis2011
- Author(s)
  Saito T, Okumoto K, Haga H, Nishise Y, Ishii R, Sato C, Watanabe H, Okada A, Ikeda M, Togashi H, Ishikawa T, Terai S, Sakaida I, Kawata S
- Journal Title
  
  Stem Cells Dev
  
  Pages: 1503-1510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Expression of the RNA-binding protein Musashi1 in adult liver stem-like cells2010
- Author(s)
  Hattori E, Shu HJ, Saito T, Okumoto K, Haga H, Yokozawa J, Ito J, Watanabe H, Saito K, Togashi H, Kawata S
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 432-437
- NAID
  10027291781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Enhanced expression of fibroblast growth factor 2 in bone marrow cells and its potential role in the differentiation of hepatic epithelial stem-like cells into the hepatocyte lineage2010
- Author(s)
  Haga H, Saito T, Okumoto K, Ugajin S, Sato C, Ishii R, Nishise Y, Ito J, Watanabe H, Saito K, Togashi H, Kawata S
- Journal Title
  
  Cell Tissue Res
  
  Volume: 343 Pages: 371-378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C2010
- Author(s)
  Sanjo M, Saito T, Nishise Y, Haga H, Okumoto K, Ito J, Watanabe H, Saito K, Togashi H, Fukuda K, Imai Y, El Shamy A, Deng L, Shoji I, Hotta H, Kawata S
- Journal Title
  
  J Med Virol
  
  Volume: 82 Pages: 1364-1370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Secondary structure of the amino-terminal region of HCV NS3 and virological response to pegylated interferon plus ribavirin therapy for chronic hepatitis C2010
- Author(s)
  Sanjo M, Saito T, Ishii R, Nishise Y, Haga H, Okumoto K, Ito J, Watanabe H, Saito K
- Journal Title
  
  J Med Virol
  
  Volume: 82(8) Pages: 1364-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590756
[Journal Article] Relationship between alcohol consumption and serum adiponection levels : the Takahata study-a cross-sectional study of a healthy Japanese population2010
- Author(s)
  Nishise Y, Saito T, Makino N, Okumoto K, Ito JI, Watanabe H, Saito K, Togashi H, Ikeda C, Kubota I, Daimon M, Kato T, Fukao A, Kawata S
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 95 Pages: 3828-3835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Clearance of hepatitis C in chimpanzees is associated with intrahepatic T-cell perforin expression during late acute phase2010
- Author(s)
  Watanabe H, Wells F, Major ME
- Journal Title
  
  J Viral Hepatitis
  
  Volume: 17 Pages: 245-253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Relationship between alcohol consumption and serum adiponection levels : the Takahata study- a cross-sectional study of a healthy Japanese population2010
- Author(s)
  Nishise Y, Saito T, Watanabe H, et al
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 95 Pages: 3828-3835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity2009
- Author(s)
  Zhang P, Zhong L, Struble EB, Watanabe H, Kachko A, Mihalik K, Virata-Theimer ML, Alter HJ, Feinstone S, Major ME
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106(18) Pages: 7537-7541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] T-cell vaccines that elicit effective immune responses against HCV in chimpanzees may create greater immune pressure for viral mutation2009
- Author(s)
  Zubkova I, Choi YH, Chang E, Pirollo K, Uern T, Watanabe H, Wells F, Kachko A, Krawczynski K, Major ME
- Journal Title
  
  Vaccine
  
  Volume: 27 Pages: 2594-2602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity.2009
- Author(s)
  Zhang P, Zhong L.Struble EB, Watanabe H, et.al
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 7537-7541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Impact of metabolic syndrome on elevated serum alanine aminotransferase levels in the Japanese population2009
- Author(s)
  Saito T, Nishise Y, Makino N, Haga H, Ishii R, Okumoto K, Ito JI, Watanabe H, Saito K, Takeda H, Togashi H, Kubota I, Daimon M, Kato T, Kawata S
- Journal Title
  
  Metabolism
  
  Volume: 58 Pages: 1067-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] T-cell vaccines that elicit effective immune responses against HCV in chimpanzees may create greater immune pressure for viral mutation.2009
- Author(s)
  Zubkova I, Choi Y.H., Watanabe H, et.al
- Journal Title
  
  Vaccine 27
  
  Pages: 2594-2602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590757
[Journal Article] Transmission of hepatitis C virus quasispecies between human adults2004
- Author(s)
  Sitao T, Watanabe H, Shao L, et al.
- Journal Title
  
  Hepatol Res. 30-2
  
  Pages: 57-62
- NAID
  10018025222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590507
[Journal Article] Transmission of hepatitis C virus quasispecies between human adults2004
- Author(s)
  Sitao T, Watanabe H, Shao L, et al.
- Journal Title
  
  Heptol Res 30・2
  
  Pages: 57-62
- NAID
  10018025222
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590507
[Presentation] HCVキャリアコホートにおけるM2BPGiの肝線維化および肝発がん予測に対する有用性2016
- Author(s)
  渡辺久剛、伊藤麻衣、水野　恵、奥本和夫、斎藤貴史、上野義之
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  東京ベイ幕張ホール（千葉県幕張市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Glyco-isomer of serum Mac-2-binding protein is associated with the risk of developing hepatocellular carcinoma after achieving sustained viral response in Japanese chronic hepatitis C patients.2016
- Author(s)
  Watanabe H, Ito M, Nakazawa Y, Ito N, Ishihama K.
- Organizer
  Digestive Disease Week 2016
- Place of Presentation
  サンディエゴコンベンションセンター（サンディエゴ、カリフォルニア、アメリカ合衆国）
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] DAA製剤を用いたIFN-free治療における治療成績と難治要因2015
- Author(s)
  渡辺久剛、水野　恵、勝見智大、奥本和夫、斎藤貴史、上野義之
- Organizer
  第19回日本肝臓学会大会
- Place of Presentation
  グランドプリンス高輪（東京都品川区）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 当県の肝炎ネットワークにおけるHCV薬剤耐性変異スクリーニングとインターフェロンフリー治療導入アウトカム2015
- Author(s)
  渡辺久剛、水野　恵、勝見智大、奥本和夫、斎藤貴史、上野義之
- Organizer
  第51回日本肝臓学会総会（ワークショップ）
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] インターフェロンフリー治療における薬剤耐性変異と治療効果への影響2015
- Author(s)
  渡辺久剛、水野　恵、勝見智大、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  鶴屋東館（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] HBV核酸アナログ治療例における線維化マーカーの推移と肝発癌2015
- Author(s)
  渡辺久剛、佐藤智佳子、水野　恵、勝見智大、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第101回日本消化器病学会総会（プレナリーセッション）
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Polymorphisms consisting of (TA)n dinucleotide repeat near IL28B gene could improve the predictive value for HCV spontaneous clearance with IL28B SNPs.2013
- Author(s)
  Sugiyama M, Hiramine S, Furusho N, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K, Masaki N, and Mizokami M.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington Convention Center, Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.2013
- Author(s)
  Tomita K, Haga H, Mizuno K, Katsumi T, Tomita K, Saito C, Okumoto K, Nishise Y, Watanabe H, Saito T, and Ueno Y.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington Convention Center, Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] CRM197, an inhibitor of HB-EGF, can suppress the growth of human hepatocellular carcinoma cells in vitro and in vivo.2013
- Author(s)
  Kawata S, Ugajin S, Yokozawa J, Watanabe H, Saito T, Inui Y, and Ueno Y.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington Convention Center, Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Is microRNA-224 a potential therapeutic target for HCC?2013
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] Predictive Value of hepatitis B Virus Genotypes on the Responses to Long-term Nucleoside Analogue Therapy in Patients with Chronic Hepatitis B.2013
- Author(s)
  Watanabe H, Saito C, Mizuno K, Katsumi T, Tomita K, Okumoto K, Nishise Y, Saito T, and Ueno Y.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington Convention Center, Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Ability of miRNA profiling to distinguish the clinical course of patients with primary biliary cirrhosis: comprehemsive analysis with deep sequencing.2013
- Author(s)
  Katsumi T, Ninomiya M, Mizuno K, Tomita K, Saito C, Okumoto K, Nishise Y, Watanabe H, Saito T, Shimosegawa T, and Ueno Y.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington Convention Center, Washington DC（USA）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Identification of miR-224 target genes and pathways related to hepatocellular carcinoma2012
- Author(s)
  Zhang XH, Sho R, Watanabe H, et al
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場 (福岡)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] The Use of RNAi-based Screens to Identify Host Factors Involved in HCV Replication2012
- Author(s)
  Sho R, Zhang XH, Watanabe H, et al
- Organizer
  The 10th JSH Single Topic Conference “Hepatitis C:Best Practice Based on Science”
- Place of Presentation
  KEIO PLAZA HOTEL (Shinjuku, Tokyo)
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] Clearance of hepatitis C virus in chimpanzees is associated with intrahepatic perforin expression during the late acute phase2010
- Author(s)
  Watanabe H, et al
- Organizer
  18th United European Gastroenterology Week
- Place of Presentation
  スペイン、バルセロナ
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Incidence of hepatocellular carcinoma after achieving sustained virological response to interferon therapy for chronic hepatitis C2010
- Author(s)
  Watanabe H, Saito T, Ishii R, Sato C, Haga H, Sanjo M, Okumoto K, Nishise Y, Ito J, Saito K, Kawata S
- Organizer
  The 61th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston,USA
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] HCVコホートにおけるウイルス自然治癒および肝発癌の検討2010
- Author(s)
  渡辺久剛, ほか
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形県山形市ホテルメトロポリタン山形
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Incidence of hepatocellular carcinoma after achieving sustained virological response to interferon therapy for chronic hepatitis C2010
- Author(s)
  Watanabe H, et al
- Organizer
  61th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  米国、ボストン
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] HCVコホート研究による持続感染者の自然経過2010
- Author(s)
  渡辺久剛, 斎藤貴史, 西瀬雄子, 邵力, 佐藤智佳子, 石井里佳, 芳賀弘明, 三條麻衣, 奥本和夫, 伊藤純一, 斉藤孝治, 石橋正道, 冨樫整, 新澤陽英, 河田純男
- Organizer
  第46回日本肝臓学会総会サテライトシンポジウム「HCV感染のnatural courseを探る:わが国におけるコホート研究」
- Place of Presentation
  山形市山形テルサ
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Expression Profiling of TLR Signaling Pathway Genes in Human Hepatocytes Infected with Cell Culture-produced Hepatitis C Virus2010
- Author(s)
  Sho R, Zhang XH, Watanabe H
- Organizer
  The 20th Conference of the APASL
- Place of Presentation
  Beijing・China National Convention Center
- Data Source
  KAKENHI-PROJECT-20590756
[Presentation] B型肝炎ジェノタイプB型高浸淫地域における急性B型肝炎の実態2010
- Author(s)
  渡辺久剛, 斎藤貴史, 西瀬雄子, 佐藤智佳子, 石井里佳, 芳賀弘明, 三條麻衣, 奥本和夫, 伊藤純一, 斉藤孝治, 冨樫整, 新澤陽英, 河田純男
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  横浜市パシフィコ横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] HCVコホートにおけるウイルス自然治癒および肝発癌の検討2010
- Author(s)
  渡辺久剛, 斎藤貴史, 西瀬雄子, 佐藤智佳子, 石井里佳, 芳賀弘明, 三條麻衣, 奥本和夫, 伊藤純一, 斉藤孝治, 冨樫整, 新澤陽英, 河田純男
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形市ホテルメトロポリタン山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] HCV培養細胞感染系におけるTLRシグナル伝達関連遺伝子の発現解析2010
- Author(s)
  邵力, 渡辺久剛, 齋藤貴史
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形市・山形国際ホテル
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20590756
[Presentation] B型肝炎ジェノタイプB型高浸淫地域における急性B型肝炎の実態2010
- Author(s)
  渡辺久剛, ほか
- Organizer
  第14回日本肝臓学会大会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Clearance of hepatitis C virus in chimpanzees is associated with intrahepatic perforin expression during the late acute phase2010
- Author(s)
  Watanabe H, Wells F, Saito T, Sato C, Ishii R, Haga H, Sanjo M, Okumoto K, Nishise Y, Ito J, Saito K, Kawata S, Major ME
- Organizer
  18th United European Gastroenterology Week
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Genetic variation in the IKK/NF-κB pathway and the live fibrosis progression in chronic hepatitis C2009
- Author(s)
  Shao L, Watanabe H, Saito T
- Organizer
  The 19th Conference of the APASL
- Place of Presentation
  Hong Kong・Hong Kong Convention and Exhibition Center
- Data Source
  KAKENHI-PROJECT-20590756
[Presentation] Real-time PCR法を用いたHCV持続感染者におけるウイルス自然陰性化の検討2009
- Author(s)
  渡辺久剛
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] A Long-Term Population-Based Cohort Study in an Endemic Area of Hepatitis C Virus in Japan : Spontaneous Elimination of Serum HCV RNA Detected by the Real-Time PCR System2009
- Author(s)
  Watanabe H, Saito T, Shao L, Nishise Y, Ishii R, Haga H, Okumoto K, Ito J, Saito K, Shinzawa H, Kawata S
- Organizer
  13th International Symposium on Viral Hepatitis and Liver Disease
- Place of Presentation
  Washington DC, USA
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Natural Clearance of Hepatitis C Virus (HCV) RNA in Chronic HCV Carriers : A Long-Term Cohort Study in an Endemic Area of HCV Infection in Japan2009
- Author(s)
  Watanabe H, Saito T, Nishise Y, Sasaki Y, Sato C, Ishii R, Haga H, Sanjo M, Okumoto K, Ito J, Saito K, Shinzawa H, Kawata S
- Organizer
  60th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, USA
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Real-time PCR法を用いたHCV持続感染者におけるウイルス自然陰性化の検討2009
- Author(s)
  渡辺久剛, 斎藤貴史, 西瀬雄子, 佐藤智佳子, 宇賀神智, 石井里佳, 芳賀弘明, 三條麻衣, 奥本和夫, 伊藤純一, 斉藤孝治, 冨樫整, 新澤陽英, 河田純男
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸市神戸ポートピアホテル
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Natural Clearance of Hepatitis C Virus(HCV)RNA in Chronic HCV Carriers : A Long-Term Cohort Study in an Endemic Area of HCV Infection in Japan. A2009
- Author(s)
  渡辺久剛, et al.
- Organizer
  60th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  米国、ボストン
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Genetic variation in the IKK/NF-κ B pathway and the live fibrosis progression in chronic hepatitis C2009
- Author(s)
  Shao L, Ishii K, Watanabe H, Saito T, et.al.
- Organizer
  19th Conference of the APASL
- Place of Presentation
  Hong Kong
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20590756
[Presentation] Profile of Toll-like receptor signaling pathway gene expression in human hepatocytes that carry self-replicating HCV replicons2008
- Author(s)
  Zhang XH, Sho R, Saito T, Watanabe H, et.al.
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20590756
[Presentation] 1a/2a chimera HCV培養細胞感染系を用いた中和抗体レベルの解析2008
- Author(s)
  渡辺久剛
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2008-06-04
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] 1a/2a chimera HCV培養細胞感染系を用いたHCV中和抗体レベルの解析2008
- Author(s)
  渡辺久剛, 斉藤貴史, 河田純男
- Organizer
  シンポジウム「C型ウイルス肝炎治療の新潮流」第44回日本肝臓学会総会
- Place of Presentation
  松山市愛媛県県民文化会館
- Year and Date
  2008-06-05
- Data Source
  KAKENHI-PROJECT-20590757
[Presentation] Telaprevir（TVR）3剤療法でのTVR用量別治療効果と安全性．
- Author(s)
  渡辺久剛、勝見智大、冨田恭子、佐藤智佳子、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  高輪プリンスホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 肝再生におけるエピレグリンの役割と機能解析
- Author(s)
  冨田恭子、芳賀弘明、勝見智大、佐藤智佳子、石井里佳、奥本和夫、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 再燃を繰り返す自己免疫性肝炎に対する免疫抑制剤投与に関する検討
- Author(s)
  奥本和夫、水野　恵、勝見智大、佐藤智佳子、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第40回日本肝臓学会東部会
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 高度肝障害時にEpiregulinは肝前駆細胞を誘導・増殖させることにより肝再生に寄与する
- Author(s)
  冨田恭子、芳賀弘明、水野　恵、勝見智大、佐藤智佳子、奥本和夫、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] アルコール性肝障害と非アルコール性脂肪性肝炎を背景とした肝癌症例の臨床的特徴．
- Author(s)
  佐藤智佳子、渡辺久剛、上野義之
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  高輪プリンスホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Association between (TA)n dinucleotide repeat near IL28B gene and HCV spontaneous clearance in Japanese and African American.
- Author(s)
  Sugiyama M, Hiramine S, Furusyo N, Ido A, Tsubouchi H, Watanabe H, Ueno Y, Korenaga M, Murata K, Masaki N, Kanto T, Hayashi J, Thomas D, Mizokami M.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] HBV遺伝子型からみたB型慢性肝疾患に対する核酸アナログ治療反応性とウイルス抗原量スコア化による中止可能性の検討
- Author(s)
  佐藤智佳子、渡辺久剛、勝見智大、冨田恭子、石井里佳、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] ソラフェニブ治療例における効果のある症例と増悪症例の検討
- Author(s)
  奥本和夫、勝見智大、冨田恭子、佐藤智佳子、石井里佳、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 糖尿病患者では潜在的NASHが混在し、NASHでは肝病態進展に糖尿病が促進的役割を果たす
- Author(s)
  佐藤智佳子、渡辺久剛、上野義之
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] C型肝炎ウイルス1bのNS3領域蛋白質2次構造を基にしたサブグループ分類と肝細胞癌発生の関連に関する前向き研究　第3報
- Author(s)
  西瀬雄子、斎藤貴史、勝見智大、冨田恭子、佐藤智佳子、石井里佳、奥本和夫、渡辺久剛、今井康陽、堀田博、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] C型肝炎患者の肝関連イベントおよび生命予後の予測にはARFIによる肝硬度および血清肝線維化スコアが有用である
- Author(s)
  西瀬雄子、渡辺久剛、冨田恭子、勝見智大、佐藤智佳子、奥本和夫、斎藤貴史、上野義之
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 原発性胆汁性肝硬変における血清内microRNAの発現とバイオマーカーとしての可能性
- Author(s)
  勝見智大、二宮匡史、冨田恭子、佐藤智佳子、石井里佳、奥本和夫、西瀬雄子、渡辺久剛、斎藤貴史、下瀬川徹、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 日本人C型肝炎患者におけるインターフェロンλ4遺伝子多型性の検討
- Author(s)
  渡辺久剛, 邵力, 上野義之
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京国際フォーラム, 東京
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] 生活習慣からみた非B非C肝癌の臨床的特徴と囲い込みのためのリスクファクター
- Author(s)
  渡辺久剛、佐藤智佳子、上野義之
- Organizer
  第18回日本肝臓学会大会
- Place of Presentation
  ポートピアホテル（神戸）
- Year and Date
  2014-10-23 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] HBV 遺伝子型からみた自然経過観察例および核酸アナログ治療例のHBs抗原陰性化と肝発癌予後
- Author(s)
  渡辺久剛、佐藤智佳子、水野　恵、勝見智大、冨田恭子、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] ゲノタイプB高浸淫地区における免疫抑制・化学療法を受けたHBV既往感染者のHBV再活性化の検討．
- Author(s)
  西瀬雄子、奥本和夫、冨田恭子、勝見智大、佐藤智佳子、阿蘓里佳、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  高輪プリンスホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] C型慢性肝炎SVR後の線維化マーカーの推移と肝発癌リスクの検討．
- Author(s)
  渡辺久剛、阿蘇里佳、上野義之
- Organizer
  第40回日本肝臓学会東部会（パネルディスカッション）
- Place of Presentation
  京王プラザホテル（東京）
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 肝動脈化学塞栓療法におけるシスプラチン製剤とアドリアマイシンによるランダム化比較試験（RCT）に基づいた有効性、安全性の検討
- Author(s)
  奥本和夫、渡辺久剛、上野義之
- Organizer
  第50回日本肝臓学会総会（ワークショップ）
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] ジェノタイプの感染実態の変遷とB型肝炎キャリアおよび急性肝炎例におけるジェノタイプの臨床的意義
- Author(s)
  渡辺久剛、佐藤智佳子、上野義之
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Genetic polymorphism in interferon-λ4 gene and treatment response to peginterferon and ribavirin in Japanese chronic hepatitis C
- Author(s)
  Watanabe H, Sho R, Saito T, et al
- Organizer
  65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  John B. Hynes Veterans Memorial Convention Center, Boston
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590953
[Presentation] 当科における肝硬変の成因別実態と合併症の臨床的特徴
- Author(s)
  水野　恵、渡辺久剛、阿蘇里佳、宇賀神智、勝見智大、冨田恭子、佐藤智佳子、奥本和夫、西瀬雄子、斎藤貴史、上野義之
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] PBCの臨床病型による定型例・非定型例の予後の検討．
- Author(s)
  勝見智大、渡辺久剛、上野義之
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  高輪プリンスホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] ウイルソン病肝硬変患者に対する酢酸亜鉛製剤の有用性について．
- Author(s)
  奥本和夫、水野　恵、勝見智大、冨田恭子、佐藤智佳子、西瀬雄子、渡辺久剛、斎藤貴史、上野義之
- Organizer
  第55回日本消化器病学会大会
- Place of Presentation
  高輪プリンスホテル（東京）
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 日本人C型肝炎患者におけるインターフェロンλ4遺伝子多型性の検討
- Author(s)
  渡辺久剛、邵　力、上野義之
- Organizer
  第100回日本消化器病学会総会（シンポジウム）
- Place of Presentation
  京王プラザ（東京）
- Year and Date
  2014-04-26 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] Genetic polymorphism in interferon-λ4 gene and treatment response to peginterferon and ribavirin in Japanese chronic hepatitis C.
- Author(s)
  Watanabe H, Sho Ri, Saito T, Mizuno K, Katsumi T, Saito C, Okumoto K, Nishise Y and Ueno Y.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Hynes Convention Center, Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-25460974
[Presentation] 本県における肝炎対策の現状と課題をふまえた「やまがた肝炎ネットワーク」の構築と肝疾患診療連携体制
- Author(s)
  渡辺久剛、斎藤貴史、上野義之
- Organizer
  第50回日本肝臓学会総会（ワークショップ）
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25460974

1. SHO Ri (80344787)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. SAITO Takafumi (80250918)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SAITO Koji (90250919)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KAWATA Sumio (90183285)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TOGASHI Hitoshi (60192209)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. FUKAO Akira (80156736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ISHII Rika (60466612)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
8. ZHANG Xuhong (10292442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. TAKAHASHI Tatuya (50304928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 斎藤貴史

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results

WATANABE Hisayoshi 渡辺 久剛

Research Projects

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Metabolomic profile of hepatitis C virus-infected hepatocytesPrincipal Investigator

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A translational research on miR-224: towards novel diagnostic and therapeutic approach for hepatocellular carcinoma

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RNA interference screen for host factors required for HCV replication

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Mechanism of Neutralization using Infectious Hepatitis C Chimeric VirusesPrincipal Investigator

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新しい肝病態、アルギニントランスポーター欠損症における門脈循環障害の分子機構解明Principal Investigator

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Development of liver regeneration therapy against severe hepatic failure based on stem cell science -Differentiation and growth of hepatic stem cell and cell transplantation.

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Interaction of alcohol consumption and a single nucleotide polymorphism in aldehyde dehydrogenase 2 (ALDH2) on the susceptibility to hepatocellular carcinoma in Japanese patients with hepatitis C

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B型肝炎ウイルス変異株におけるウイルス蛋白発現抑制に関する研究Principal Investigator

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Development of strategic therapy for severe hepatic failure using regenerative medicine-Isolation of hepatic stem cell expressing musashi-1 gene and cell therapy

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Development of hepatic anti-fibrotic therapy targeted to angiotensin II receptor antagonist-soppression of collagen production in the Ito cell via TGF-β

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[Book] 厚生労働省科学研究費補助金（肝炎等克服緊急対策事業）平成26年度総括・分担研究報告書「C型肝炎の新規診断法や新規治療法を開発するためのゲノムワイド関連解析の手法を用いた宿主因子の解析に関する研究」2015

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[Book] 日本臨床増刊号「新ウイルス性肝炎学」2015

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[Book] 消化器内科2014

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[Book] Hepatology Practice 「C型肝炎の診療を極める」2014

WATANABE Hisayoshi 渡辺久剛