YUI SHIRO 油井史郎

… Alternative Names

Yui Shiro 油井史郎

油井史郎ユイシロウ

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Researcher Number	00383886
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京医科歯科大学, 統合研究機構, 准教授 2019: 東京医科歯科大学, 統合研究機構, 講師 2018: 東京医科歯科大学, 統合研究機構, 助教 2012: 東京医科歯科大学, 医歯(薬)学総合研究科, メディカルフェロー
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator オルガノイド移植 / オルガノイド移植治療 / 可塑性 / 幹細胞 / 上皮細胞互換性 / 人工肝細胞 / TMDU細胞 / 上皮細胞胎児化 / 細胞外基質依存性上皮細胞可塑性 / リプログラミング … More / 上皮傷害 / 胎児型上皮への運命転換 / Lgr5 positive stem cells / Transplantation / Mathematical modeling / FEnS / 上皮移植モデル / 数理モデル / 胎児腸上皮細胞 / I型コラーゲン / 腸上皮オルガノイド / 腸上皮再生機構 / 疾患感受性遺伝子 / 再生医療 / 腸管上皮初代培養技術 / 遺伝子操作技術 … More Except Principal Investigator 炎症性腸疾患 / 全身制御 / ArtDO / ArtDo / オルガノイドデザイン / 大腸粘膜再生 / 炎症性腸疾患？ / 大腸炎 / 胚細胞 / 腸上皮オルガノイド / オルガノイド / 潰瘍性大腸炎 / 粘膜再生 / 杯細胞 / 複合臓器体外モデル / iPS細胞 / iPS細胞複合臓器体外モデル / 臓器間制御 / 臓器共培養 / 臓器間制御機構 / ヒトオルガノイド Less

腸オルガノイドによる大腸組織再生の最適化Principal Investigator
- Principal Investigator
  
  油井史郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
オルガノイドデザインによる臓器創出と移植による全身制御
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Juntendo University
  Tokyo Medical and Dental University
Epithelial cell plasticity and reversibility of primitive endodermal tissuesPrincipal Investigator
- Principal Investigator
  
  Yui Shiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of homeostasis mechanisms using a human in vitro multi organ model
- Principal Investigator
  
  Watanabe Mamoru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Tokyo Medical and Dental University
Identification and functional analysis of colonic label-retaining goblet cells for the application to regeneration of the inflamed mucosa.
- Principal Investigator
  
  Okamoto Ryuichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Identification of molecular mechanisms in the wound associated reprogramming of intestinal epithelial cellsPrincipal Investigator
- Principal Investigator
  
  Yui Shiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
培養大腸上皮細胞への遺伝子導入技術の開発Principal Investigator
- Principal Investigator
  
  油井史郎
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019 2018 2012 Other

All Journal Article Presentation Book Other

[Book] 腸上皮の老化に関わるストレス応答の2方向性2021
- Author(s)
  小笠原暢彦、油井史郎、渡辺守
- Total Pages
  5
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20H03657
[Book] 腸上皮の老化に関わるストレス応答の2 方向性2021
- Author(s)
  小笠原暢彦、油井史郎、渡辺守
- Total Pages
  5
- Publisher
  生体の科学
- Data Source
  KAKENHI-PROJECT-20H03657
[Book] 分子消化器病 9巻３号2012
- Author(s)
  油井史郎、中村哲也、渡辺守
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24790684
[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024
- Author(s)
  Ogasawara N, Kano Y, Yoneyama Y, Kobayashi S, Watanabe S, Kirino S, Velez-Bravo FD, Hong Y, Ostapiuk A, Lutsik P, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Kinugasa Y, Ohashi K, Watanabe M, Okamoto R, Tejpar S, Yui S.
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 3 Pages: 109247-109247
- DOI
  10.1016/j.isci.2024.109247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-23K07394, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-23K27578
[Journal Article] Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment2023
- Author(s)
  Watanabe Satoshi、Ogasawara Nobuhiko、Kobayashi Sakurako、Kirino Sakura、Inoue Masami、Hiraguri Yui、Nagata Sayaka、Shimizu Hiromichi、Ito Go、Mizutani Tomohiro、Nemoto Yasuhiro、Tsuchiya Kiichiro、Okamoto Ryuichi、Watanabe Mamoru、Yui Shiro
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 58 Issue: 4 Pages: 379-393
- DOI
  10.1007/s00535-023-01959-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08048, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-23K07394, KAKENHI-PROJECT-22K19519, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23K27578
[Journal Article] The Effect of Vitamin D3 and Valproic Acid on the Maturation of Human-Induced Pluripotent Stem Cell-Derived Enterocyte-Like Cells2023
- Author(s)
  Leo Sylvia、Kato Yusuke、Wu Yumeng、Yokota Mutsumi、Koike Masato、Yui Shiro、Tsuchiya Kiichiro、Shiraki Nobuaki、Kume Shoen
- Journal Title
  
  Stem Cells
  
  Volume: 41 Issue: 8 Pages: 775-791
- DOI
  10.1093/stmcls/sxad042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18281, KAKENHI-PROJECT-22K07523, KAKENHI-PROJECT-23K06323, KAKENHI-PROJECT-22K19543, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-21H02978, KAKENHI-PROJECT-23K27578
[Journal Article] Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease2022
- Author(s)
  Shuji Hibiya, Kazuo Ohtsuka, Kento Takenaka, Ami Kawamoto, Yusuke Matsuyama, Yumi Udagawa, Maiko Motobayashi, Hiromichi Shimizu, Toshimitsu Fujii, Eiko Saito, Masakazu Nagahori, Ryuichi Okamoto, Mamoru Watanabe
- Journal Title
  
  BMC Gastroenterol.
  
  Volume: 22 Issue: 1 Pages: 218-218
- DOI
  10.1186/s12876-022-02300-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-21K15918, KAKENHI-PROJECT-21K15992
[Journal Article] Transplantation of intestinal organoids into a mouse model of colitis2022
- Author(s)
  Watanabe Satoshi、Kobayashi Sakurako、Ogasawara Nobuhiko、Okamoto Ryuichi、Nakamura Tetsuya、Watanabe Mamoru、Jensen Kim B.、Yui Shiro
- Journal Title
  
  Nature Protocols
  
  Volume: 17 Issue: 3 Pages: 649-671
- DOI
  10.1038/s41596-021-00658-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-21K07977, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03657
[Journal Article] Artificial intelligence for endoscopy in inflammatory bowel disease2022
- Author(s)
  Takenaka Kento、Kawamoto Ami、Okamoto Ryuichi、Watanabe Mamoru、Ohtsuka Kazuo
- Journal Title
  
  Intestinal Research
  
  Volume: 20 Issue: 2 Pages: 165-170
- DOI
  10.5217/ir.2021.00079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00472
[Journal Article] Transmural remission characterized by high biologic concentrations demonstrates better prognosis in Crohn's disease2022
- Author(s)
  Kento Takenaka, Ami Kawamoto, Yoshio Kitazume, Toshimitsu Fujii, Yumi Udagawa, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  J Crohns Colitis.
  
  Volume: - Issue: 6 Pages: 855-862
- DOI
  10.1093/ecco-jcc/jjac185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-23K07352, KAKENHI-PROJECT-23K07413, KAKENHI-PROJECT-23K27579
[Journal Article] Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease2022
- Author(s)
  Kento Takenaka, Yoshio Kitazume, Ami Kawamoto, Toshimitsu Fujii, Yumi Udagawa, Ryosuke Wanatabe, Hiromichi Shimizu, Shuji Hibiya, Masakazu Nagahori, Kazuo Ohtsuka, Hiroyuki Sato, Akihiro Hirakawa, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  Am J Gastroenterol.
  
  Volume: - Issue: 6 Pages: 1028-1035
- DOI
  10.14309/ajg.0000000000002127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K15991, KAKENHI-PROJECT-23K07352, KAKENHI-PROJECT-23K07413, KAKENHI-PROJECT-23K27579
[Journal Article] Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis.2022
- Author(s)
  Tamura A, Ito G, Matsuda H, Nibe-Shirakihara Y, Hiraoka Y, Kitagawa S, Hiraguri Y, Nagata S, Aonuma E, Otsubo K, Nemoto Y, Nagaishi T, Watanabe M, Okamoto R, Oshima S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 628 Pages: 147-154
- DOI
  10.1016/j.bbrc.2022.08.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02897, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-21K15968
[Journal Article] Extracellular Matrix Interactions Provide Tumor Cells With an Escape Mechanism for Commitment to Differentiation2022
- Author(s)
  Schweiger Pawel J.、Le Bouteiller Marie、Yui Shiro、Thodberg Malte、Clement Ditte、Jensen Kim B.
- Journal Title
  
  Gastroenterology
  
  Volume: 163 Issue: 6 Pages: 1688-1690.e3
- DOI
  10.1053/j.gastro.2022.08.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03657
[Journal Article] Suspension culture in a rotating bioreactor for efficient generation of human intestinal organoids2022
- Author(s)
  Takahashi Junichi、Mizutani Tomohiro、Sugihara Hady Yuki、Nagata Sayaka、Kato Shu、Hiraguri Yui、Takeoka Sayaka、Tsuchiya Mao、Kuno Reiko、Kakinuma Sei、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 2 Issue: 11 Pages: 100337-100337
- DOI
  10.1016/j.crmeth.2022.100337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21H02896
[Journal Article] Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study2022
- Author(s)
  Kento Takenaka, Toshimitsu Fujii, Ami Kawamoto, Kohei Suzuki, Hiromichi Shimizu, Chiaki Maeyashiki, Osamu Yamaji, Maiko Motobayashi, Akira Igarashi, Ryoichi Hanazawa, Shuji Hibiya, Masakazu Nagahori, Eiko Saito, Ryuichi Okamoto, Kazuo Ohtsuka, Mamoru Watanabe
- Journal Title
  
  Lancet Gastroenterol Hepatol
  
  Volume: 7 Issue: 3 Pages: 230-237
- DOI
  10.1016/s2468-1253(21)00372-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-21K07977, KAKENHI-PROJECT-21K15991, KAKENHI-PROJECT-22K07978, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-21K15918, KAKENHI-PROJECT-21K15992
[Journal Article] Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation2022
- Author(s)
  Kobayashi S, Ogasawara N, Watanabe S, Yoneyama Y, Kirino S, Hiraguri Y, Inoue M, Nagata S, Okamoto-Uchida Y, Kofuji S, Shimizu H, Ito G, Mizutani T, Yamauchi S, Kinugasa Y, Kano Y, Nemoto Y, Watanabe M, Tsuchiya K, Nishina H, Okamoto R, Yui S.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 49-49
- DOI
  10.1186/s41232-022-00237-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06544, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K08048, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21H02898
[Journal Article] Nickel particles are present in Crohn's disease tissue and exacerbate intestinal inflammation in IBD susceptible mice.2022
- Author(s)
  Hiroki Matsuda, Yoichi Nibe-Shirakihara, Akiko Tamura, Emi Aonuma, Satoko Arakawa, Kana Otsubo, Yasuhiro Nemoto, Takashi Nagaishi, Kiichiro Tsuchiya, Shigeomi Shimizu, Averil Ma, Mamoru Watanabe, Motohiro Uo, Ryuichi Okamoto, Shigeru Oshima.
- Journal Title
  
  Biochemical and Biophysical Research Communications.
  
  Volume: 592 Pages: 74-80
- DOI
  10.1016/j.bbrc.2021.12.111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20H00467, KAKENHI-PLANNED-17H06414, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02897, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-20K08304, KAKENHI-PUBLICLY-21H05743, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-21K15968, KAKENHI-WRAPUP-22H04899, KAKENHI-PUBLICLY-22H04639
[Journal Article] Activated mucosal-associated invariant T cells have a pathogenic role in a murine model of inflammatory bowel disease.2022
- Author(s)
  usuke Yasutomi, Asako Chiba, Keiichi Haga, Goh Murayama, Ayako Makiyama, Taiga Kuga, Mamoru Watanabe, Ryuichi Okamoto, Akihito Nagahara, Takashi Nagaishi, Saichiko Miyake.
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology.
  
  Volume: 13 Issue: 1 Pages: 81-93
- DOI
  10.1016/j.jcmgh.2021.08.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20K17452, KAKENHI-PROJECT-19K24002, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02964, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20K08807, KAKENHI-PROJECT-22H00472
[Journal Article] Importance of Telomere Shortening in the Pathogenesis of Ulcerative Colitis: A New Treatment From the Aspect of Telomeres in Intestinal Epithelial Cells2021
- Author(s)
  Watanabe Sho、Hibiya Shuji、Katsukura Nobuhiro、Kitagawa Sayuki、Sato Ayako、Okamoto Ryuichi、Watanabe Mamoru、Tsuchiya Kiichiro
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 16 Issue: 1 Pages: 109-121
- DOI
  10.1093/ecco-jcc/jjab115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-21K15918
[Journal Article] Functional analysis of isoflavones using patient-derived human colonic organoids2021
- Author(s)
  Tsuchiya Mao、Ito Go、Hama Minami、Nagata Sayaka、Kawamoto Ami、Suzuki Kohei、Shimizu Hiromichi、Anzai Sho、Takahashi Junichi、Kuno Reiko、Takeoka Sayaka、Hiraguri Yui、Sugihara Hady Yuki、Mizutani Tomohiro、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 542 Pages: 40-47
- DOI
  10.1016/j.bbrc.2021.01.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20K22895, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19K23990, KAKENHI-PROJECT-20K22920, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21K15992
[Journal Article] Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients2021
- Author(s)
  Kuno Reiko、Ito Go、Kawamoto Ami、Hiraguri Yui、Sugihara Hady Yuki、Takeoka Sayaka、Nagata Sayaka、Takahashi Junichi、Tsuchiya Mao、Anzai Sho、Mizutani Tomohiro、Shimizu Hiromichi、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 25 Pages: 100906-100906
- DOI
  10.1016/j.bbrep.2020.100906
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-20K22895, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17484, KAKENHI-PROJECT-19K23990, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-20K22920, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21K15992
[Journal Article] A Cellular "Hub" Function to Resolve Colitis.2021
- Author(s)
  Ito G, Yui S, Okamoto R.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 12(2) Issue: 2 Pages: 789-790
- DOI
  10.1016/j.jcmgh.2021.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22895, KAKENHI-PROJECT-20H03657
[Journal Article] Serum leucine-rich α-2 glycoprotein; a novel biomarker for small bowel mucosal activity in Crohn’s Disease.2021
- Author(s)
  Kawamoto T, Takenaka K, Hibiya S, Ohtsuka K, Okamoto R, Watanabe M
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 20 Issue: 5 Pages: e1196-e1200
- DOI
  10.1016/j.cgh.2021.06.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-20K08378, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-21K15918, KAKENHI-PROJECT-21K15991
[Journal Article] A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production.2021
- Author(s)
  Ai Minamidate, Michio Onizawa, Chikako Saito, Rie Hikichi, Tomoaki Mochimaru, Mai Murakami, Chiharu Sakuma, Takehito Asakawa, Yuichi Hiraoka, Shigeru Oshima, Takashi Nagaishi, Kiichiro Tsuchiya, Hiromasa Ohira, Ryuichi Okamoto, Mamoru Watanabe.
- Journal Title
  
  Biochemistry and Biophysics Reports.
  
  Volume: 27 Pages: 101065-101065
- DOI
  10.1016/j.bbrep.2021.101065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-20K21597, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-21H02897, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-20K08304
[Journal Article] Organoid-based regenerative medicine for inflammatory bowel diasease.2020
- Author(s)
  Okamoto R, Shimizu H, Suzuki K, Kawamoto A, Takahashi J, Kawai M, Nagata S, Hiraguri Y, Takeoka S, Sugihara HY, Yui S, Watanabe M
- Journal Title
  
  Regen Ther.
  
  Volume: 13 Pages: 1-6
- DOI
  10.1016/j.reth.2019.11.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-19K23990
[Journal Article] High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage2020
- Author(s)
  Tanaka Shohei、Nemoto Yasuhiro、Takei Yuria、Morikawa Ryo、Oshima Shigeru、Nagaishi Takashi、Okamoto Ryuichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Stutte Susanne、Watanabe Mamoru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 4 Pages: 971-977
- DOI
  10.1016/j.bbrc.2019.11.158
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-17H04024
[Journal Article] CD8αα+ T cells show amoeboid shape and frequent morphological change in?vitro, and localize to small intestinal intraepithelial region in?vivo2020
- Author(s)
  Takei Yuria、Nemoto Yasuhiro、Morikawa Ryo、Tanaka Shohei、Oshima Shigeru、Nagaishi Takashi、Okamoto Ryuichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Watanabe Mamoru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Issue: 2 Pages: 328-335
- DOI
  10.1016/j.bbrc.2019.12.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17H04024
[Journal Article] TGF-β promotes fetal gene expression and cell migration velocity in a wound repair model of untransformed intestinal epithelial cells2020
- Author(s)
  Anzai Sho、Kawamoto Ami、Nagata Sayaka、Takahashi Junichi、Kawai Mao、Kuno Reiko、Kobayashi Sakurako、Watanabe Satoshi、Suzuki Kohei、Shimizu Hiromichi、Hiraguri Yui、Takeoka Sayaka、Sugihara Hady Yuki、Yui Shiro、Oshima Shigeru、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 3 Pages: 533-541
- DOI
  10.1016/j.bbrc.2020.01.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675
[Journal Article] TP53 mutation by CRISPR system enhances the malignant potential of colon cancer.2019
- Author(s)
  Watanabe S, Tsuchiya K, Nishimura R, Shirasaki T, Katsukura N, Hibiya S, Okamoto R, Nakamura T, Watanabe M
- Journal Title
  
  Mol Cancer Res.
  
  Volume: in press Issue: 7 Pages: 1459-1467
- DOI
  10.1158/1541-7786.mcr-18-1195
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-19K17425, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-17H04024
[Journal Article] 細胞包埋材料が規定する腸上皮オルガノイドの形質2019
- Author(s)
  小林桜子、油井史郎
- Journal Title
  
  Medical Science Digest
  
  Volume: 45
- Data Source
  KAKENHI-PROJECT-18K15743
[Journal Article] Tracing the origin of adult intestinal stem cells2019
- Author(s)
  Jordi Guiu, , Shiro Yui, Samuel Martti Maimets, Perlman, Lene Lundvall, Linn Salto Mamsen, Agnete Larsen, Rasmus H Olesen, Claus Yding Andersen, Lea Langhoff Thuesen, Kristine Juul Hare, Tune H Pers, Benjamin D Simons, Kim B Jensen et al.
- Journal Title
  
  Nature
  
  Volume: 570 Issue: 7759 Pages: 107-111
- DOI
  10.1038/s41586-019-1212-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15743
[Journal Article] Stem cell-based therapy for inflammatory bowel disease.2019
- Author(s)
  Hiromichi Shimizu, Kohei Suzuki, Mamoru Watanabe, Ryuichi Okamoto
- Journal Title
  
  Intest Res
  
  Volume: 17 Issue: 3 Pages: 311-316
- DOI
  10.5217/ir.2019.00043
- Open Access
- Data Source
  KAKENHI-PROJECT-19H03634, KAKENHI-PROJECT-19K17484
[Journal Article] Single cell analysis of Crohn’s disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties2018
- Author(s)
  Suzuki Kohei、Murano Tatsuro、Shimizu Hiromichi、Ito Go、Nakata Toru、Fujii Satoru、Ishibashi Fumiaki、Kawamoto Ami、Anzai Sho、Kuno Reiko、Kuwabara Konomi、Takahashi Junichi、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Watanabe Mamoru、Okamoto Ryuichi
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 印刷中 Issue: 9 Pages: 1035-1047
- DOI
  10.1007/s00535-018-1437-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-16K09302, KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674
[Journal Article] Ubiquitin D is Upregulated by Synergy of Notch Signalling and TNF-α in the Inflamed Intestinal Epithelia of IBD Patients2018
- Author(s)
  Kawamoto Ami、Nagata Sayaka、Anzai Sho、Takahashi Junichi、Kawai Mao、Hama Minami、Nogawa Daichi、Yamamoto Kouhei、Kuno Reiko、Suzuki Kohei、Shimizu Hiromichi、Hiraguri Yui、Yui Shiro、Oshima Shigeru、Tsuchiya Kiichiro、Nakamura Tetsuya、Ohtsuka Kazuo、Kitagawa Masanobu、Okamoto Ryuichi、Watanabe Mamoru
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 13 Issue: 4 Pages: 495-509
- DOI
  10.1093/ecco-jcc/jjy180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09370, KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-17K19675, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K15743, KAKENHI-PROJECT-18K15774, KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-16H05284, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-18H02867, KAKENHI-PROJECT-17K19513, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-18H02791
[Journal Article] Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+stem cell2012
- Author(s)
  Yui S, Nakamura T, Sato T, Nemoto Y, Mizutani T, Zheng X, Ichinose S, Nagaishi T, Okamoto R, Tsuchiya K, Clevers H, and Watanabe M
- Journal Title
  
  Nature Medicine
  
  Volume: 18 Issue: 4 Pages: 618-623
- DOI
  10.1038/nm.2695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590803, KAKENHI-PROJECT-21590805, KAKENHI-PROJECT-21590806, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PROJECT-22590696, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-23890204, KAKENHI-PROJECT-24390186, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-24790684, KAKENHI-PUBLICLY-24112508, KAKENHI-PUBLICLY-24112523
[Presentation] Analysis of gene expression to elucidate the pathogenesis of pancreatic solid pseudopapillary neoplasm.2023
- Author(s)
  Hiromune Katsuda, Go Ito, Yui Hiraguri, Tomohiro Muto, Shun Ishido, Masanori Kobayashi, Hironari Yamashita, Akira Ito, Hiroaki Ono, Atsushi Kudo, Mamoru Watanabe, Minoru Tanabe, Ryuichi Okamoto
- Organizer
  UEGW2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Unveiling the gene network behind cell plasticity provides a novel insight into the therapeutic approach for human colorectal cancer2023
- Author(s)
  Ogasawara N, Kano Y, Kobayashi S, Watanabe S, Kirino S, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Watanabe M, Kinugasa Y, Ohashi Y, Okamoto R, Yui S
- Organizer
  Keystone Symposia, The resident tumor microenvironment,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27578
[Presentation] APL DOWNREGULATION IN T CELLS IN THE SETTING OF CHRONIC COLITIS.2023
- Author(s)
  Mone Fushimi, Tadahiko Inoue, Daiki Yamada, Taro Watabe, Mamoru Watanabe, Ryuichi Okamoto, Takashi Nagaish
- Organizer
  UEGW2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] ECM-niche dependent plasticity controls the acquisition of invasive phenotype in colorectal cancer2023
- Author(s)
  Ogasawara N, Kano Y, Kobayashi S, Watanabe S, Kirino S, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Watanabe M, Kinugasa Y, Ohashi Y, Okamoto R, Yui S
- Organizer
  第82回日本癌学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27578
[Presentation] Fetal-like reprogramming is the key to understand the heterogeneity of colorectal cancer.2023
- Author(s)
  Shiro Yui
- Organizer
  第41回札幌国際がんシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27578
[Presentation] ECM-niche dependent plasticity controls the acquisition of invasive phenotype in colorectal cancer2023
- Author(s)
  Nobuhiko Ogasawara, Yoshihito Kano, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Mamoru Watanabe, Yusuke Kinugasa, Kenichi Ohashi, Ryuichi Okamoto, Shiro Yui
- Organizer
  第82回日本癌学会
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] 腸上皮細胞の時相調整におけるECM-Nicheの役割解明2023
- Author(s)
  油井　史郎
- Organizer
  第22回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] Fetal-like reprogramming is the key to understand the heterogeneity of colorectal cancer.2023
- Author(s)
  Shiro Yui
- Organizer
  The 41st Sapporo International Cancer Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Unveiling the gene network behind cell plasticity provides a novel insight into the therapeutic approach for human colorectal cancer.2023
- Author(s)
  Nobuhiko Ogasawara, Yoshihito Kano, Sakurako Kobayashi, Satoshi Watanabe, Sakura Kirino, Iichiroh Onishi, Shinichi Yamauchi, Yui Hiraguri, Go Ito, Mamoru Watanabe, Yusuke Kinugasa, Kenichi Ohashi, Ryuichi Okamoto, Shiro Yui
- Organizer
  Keystone Symposia, The resident tumor microenvironment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Dissection of inflammatory and regenerative signature of intestinal epithelium via in vitro culture recapitulating the repair process.2022
- Author(s)
  Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Go Ito, Yoshito Kano, Tomohiro Mizutani, Hiromich Shimizu, Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui.
- Organizer
  Digestive Disease Week (DDW)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] Dissection of inflammatory and regenerative signature of intestinal epithelium via in vitro culture recapitulating the repair process2022
- Author(s)
  Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Go Ito, Yoshihito Kano, Tomohiro Mizutani, Hiromichi Shimizu , Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui
- Organizer
  DDW2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Application of DSS grafting assay to evaluate the potential of Cecum organoids as u useful cellular source for the treatment of colitis.2022
- Author(s)
  Satoshi Watanabe, Nobuhiko Ogasawara, Sakurako Kobayashi, Go Ito, Yoshito Kano, Tomohiro Mizutani, Hiromich Shimizu, Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui.
- Organizer
  Digestive Disease Week (DDW)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] Dissection of cancer cell plasticity in a novel defined culture system for human colorectal cancer2022
- Author(s)
  Nobuhiko Ogasawara, Sakurako Kobayashi, Satoshi Watanabe, Go Ito, Yoshihito Kano, Tomohiro Mizutani, Hiromichi Shimizu , Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui
- Organizer
  DDW2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Application of DSS-Grafting Assay to Evaluate the Potential of Cecum Organoids as a Useful Cellular Source for the Treatment of Colitis2022
- Author(s)
  Satoshi Watanabe, Nobuhiko Ogasawara, Sakurako Kobayashi , Go Ito, Yoshihito Kano, Tomohiro Mizutani, Hiromichi Shimizu , Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui
- Organizer
  DDW2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00472
[Presentation] Dissection of cancer cell plasticity in a novel defined culture system for human colorectal cancer.2022
- Author(s)
  Nobuhiko Ogasawara, Sakurako Kobayashi, Satoshi Watanabe, Go Ito, Yoshito Kano, Tomohiro Mizutani, Hiromich Shimizu, Mamoru Watanabe, Ryuichi Okamoto, Shiro Yui
- Organizer
  Digestive Disease Week (DDW)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 腸上皮細胞の胎児化機構の同定とヒト腸への応用2021
- Author(s)
  油井史郎
- Organizer
  第20回日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 13.Conceptual basis of lineage shift between intestinal epithelium and hepatocytes.2021
- Author(s)
  Sakurako Kobayashi, Satoshi Watanabe, Nobuhiko Ogasawara, Yosuke Yoneyama, Kousuke Tanimoto, Ryu Nishimura, Sayaka Nagata, Masami Inoue, Kouhei Suzuki, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Takanori Takebe, Shiro Yui
- Organizer
  第18回幹細胞シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 14.炎症・再生に関与する胎児化機構の同定とヒト腸への応用2021
- Author(s)
  油井史郎、小林桜子、渡辺諭、小笠原暢彦、井上正美、大島茂、柿沼晴、土屋輝一郎、岡本隆一、渡辺守
- Organizer
  第42回日本炎症再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 15.The art of intestinal organoids in basic research and its potential for clinical applications2021
- Author(s)
  Shiro Yui, Ryuichi Okamoto, Mamoru Watanabe
- Organizer
  ISSCR/JSRM International Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 12.ヒト腸管上皮細胞における発生・炎症・発癌オーバーラップに関する基礎研究2021
- Author(s)
  油井　史郎、岡本隆一、渡辺守
- Organizer
  第107回日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] Development of hyper plastic cellular materials by utilizing the injury associated reprogramming2020
- Author(s)
  Shiro Yui
- Organizer
  第43回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] 腸炎細胞治療におけるオルガノイド特性の最適化2020
- Author(s)
  渡辺諭、高橋純一、小林桜子、土屋輝一郎、岡本隆一、Gunnar Hansson、Kim Jensen、渡辺守、油井史郎
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20H03657
[Presentation] Conceptual basis of lineage shift between intestinal epithelium and hepatocytes2020
- Author(s)
  Sakurako Kobayashi, Satoshi Watanabe, Yosuke Yoneyama, Kousuke Tanimoto, Ryu Nishimura, Sayaka Nagata, Masami Inoue, Kouhei Suzuki, Sei Kakinuma, Kiichiro Tsuchiya, Ryuichi Okamoto, Mamoru Watanabe, Takanori Takebe, Shiro Yui
- Organizer
  Keystone Symposia, Tissue Organoids as Models of Host Physiology and Pathophysiology of Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] 消化管疾患の主役『上皮細胞』の医学研究2020
- Author(s)
  油井　史郎
- Organizer
  第19回御茶ノ水消化器疾患先端医療研究会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Long-term inflammation model using human colonic organoids2019
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Tomoaki Shirasaki, Sho Watanabe, Nobuhiro Katsukura, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe
- Organizer
  AOCC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03634
[Presentation] Establishment of chronic inflammation model using human small intestinal and colonic organoids2019
- Author(s)
  Shuji Hibiya, Kiichiro Tsuchiya, Ryu Nishimura, Sho Watanabe, Nobuhiro Katsukura, Tomoaki Shirasaki, Ryuichi Okamoto, Mamoru Watanabe
- Organizer
  UEG Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03634
[Presentation] Functional analysis of isoflavones using patient-derived intestinal organoids.2019
- Author(s)
  Kawai M, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Yui S, Okamoto R, Watanabe M
- Organizer
  AOCC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01050
[Presentation] 腸管炎症による間質線維化が誘導する上皮幹細胞の胎児型形質転換2019
- Author(s)
  油井　史郎
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Stem Cells in Gut, Who are They and How They Work, What Can We Account on Them2019
- Author(s)
  Shiro Yui
- Organizer
  The 7th Annual Meeting of Asian Organization for Crohn’s & Colitis (AOCC)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Functional analysis of isoflavones using patient-derived intestinal organoids2019
- Author(s)
  Kawai M, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Yui S, Okamoto R, Watanabe M
- Organizer
  AOCC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03634
[Presentation] 【The 6th JSGE International Topic Conference Lifestyle-related Diseases in Gastroenterology】Gastrointestinal tract（role of gut microbiome and diet）：Food-bome factors in inflammatory bowel disease2019
- Author(s)
  Ryuichi Okamoto, Mao Kawai, Minami Hama, Sayaka Nagata, Ami Kawamoto, Kohei Suzuki, Hiromichi Shimizu, Sho Anzai, Junichi Takahashi, Reiko Kuno, Sayaka Takeoka, Yui Hiraguri, Shiro Yui, Mamoru Watanabe
- Organizer
  The105th General Meeting of the Japanese Society of Gastroenterology
- Invited
- Data Source
  KAKENHI-PROJECT-19H03634
[Presentation] Stem Cells in Gut, Who are They and How They Work, What Can We Count on Them.2019
- Author(s)
  Yui S, Watanabe M
- Organizer
  AOCC 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01050
[Presentation] 患者由来腸上皮オルガノイドを用いたイソフラボン類による腸上皮機能調節機構の解析2019
- Author(s)
  川井麻央、河本亜美、永田紗矢香、安斎　翔、高橋純一、久野玲子、平栗優衣、鈴木康平、清水寛路、油井史郎、岡本隆一、渡辺　守
- Organizer
  第56回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-19H03634
[Presentation] 【The 6th JSGE International Topic Conference　Lifestyle-related Diseases in Gastroenterology】Gastrointestinal tract（role of gut microbiome and diet）.2019
- Author(s)
  Okamoto R, Kawai M, Hama M, Nagata S, Kawamoto A, Suzuki K, Shimizu H, Anzai S, Takahashi J, Kuno R, Takeoka S, Hiraguri Y, Yui S, Watanabe M
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19H01050
[Presentation] 成体由来・高可塑性腸上皮オルガノイドのリプログラミング法開発2019
- Author(s)
  油井　史郎
- Organizer
  令和元年度AMED再生医療研究交流会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Development of fetal-like hyper-plastic intestinal organoids derived from mature-adult intestine2019
- Author(s)
  Shiro Yui
- Organizer
  令和元年度　幹細胞・再生医学イノベーション創出プログラム　事業内交流会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Regenerative medicine in treatment of IBD2019
- Author(s)
  Shiro Yui
- Organizer
  Asian Pacific Digestive Week (APDW)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] 4.日本の消化器内科医が主導する世界のオルガノイド研究～IBDの病態解明から再生医療へ～2018
- Author(s)
  油井　史郎
- Organizer
  東京西部消化器先端医療勉強会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] Broad progression of research in intestinal epithelial biologyーFrom primary culture to epithelial regeneration2018
- Author(s)
  油井　史郎
- Organizer
  東京医科歯科大学湯島若手塾
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] 成体由来・高可塑性腸上皮オルガノイドのリプログラミング法開発2018
- Author(s)
  油井　史郎
- Organizer
  再生医療実現拠点ネットワークプログラム（幹細胞・再生医学イノベーション創出プログラム）平成30 年度事業内交流会
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] YAP/TAZ依存性の胎児化誘導を介した間質リモデリングの上皮再生促進機構2018
- Author(s)
  油井　史郎、岡　本隆一、土屋　輝一郎、中村　哲也、渡辺　守
- Organizer
  第4回G-PLUS
- Data Source
  KAKENHI-PROJECT-18K15743
[Presentation] マウス及びヒトの正常な腸管上皮初代培養法の確立
- Author(s)
  油井　史郎
- Organizer
  第3回 Japan Gut Club
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790684
[Presentation] Regeneration of damaged colon tissue by transplanted colon stem cells maintained and expanded in vitro.
- Author(s)
  Yui S, Nakamura T et al
- Organizer
  10th Stem Cell Research Symposium
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PROJECT-24790684
[]

1. Watanabe Mamoru (10175127)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
2. 柿沼晴 (30372444)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 土屋輝一郎 (40376786)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. Okamoto Ryuichi (50451935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. 鬼澤道夫 (30783352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 武部貴則 (20612625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 伊藤剛 (20733900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. KOFUJI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 長堀正和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 中村哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 永石宇治

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
12. 小林真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 水谷知裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 大塚和朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 齊藤詠子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 米山鷹介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YUI SHIRO 油井 史郎

Yui Shiro 油井 史郎

油井 史郎 ユイ シロウ

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腸オルガノイドによる大腸組織再生の最適化Principal Investigator

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オルガノイドデザインによる臓器創出と移植による全身制御

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Epithelial cell plasticity and reversibility of primitive endodermal tissuesPrincipal Investigator

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Analysis of homeostasis mechanisms using a human in vitro multi organ model

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Identification and functional analysis of colonic label-retaining goblet cells for the application to regeneration of the inflamed mucosa.

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Identification of molecular mechanisms in the wound associated reprogramming of intestinal epithelial cellsPrincipal Investigator

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培養大腸上皮細胞への遺伝子導入技術の開発Principal Investigator

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[Book] 腸上皮の老化に関わるストレス応答の2方向性2021

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[Book] 腸上皮の老化に関わるストレス応答の2 方向性2021

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[Book] 分子消化器病 9巻３号2012

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[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024

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[Journal Article] Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment2023

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[Journal Article] The Effect of Vitamin D3 and Valproic Acid on the Maturation of Human-Induced Pluripotent Stem Cell-Derived Enterocyte-Like Cells2023

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[Journal Article] Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease2022

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YUI SHIRO 油井史郎

Yui Shiro 油井史郎

油井史郎ユイシロウ