Kimoto Sohei 紀本創兵

… Alternative Names

KIMOTO SOHEI 紀本創兵

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Researcher Number	00405391
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 和歌山県立医科大学, 医学部, 教授 2022: 奈良県立医科大学, 医学部, 学内講師 2019 – 2022: 奈良県立医科大学, 医学部, 講師 2018 – 2019: 奈良県立医科大学, 医学部, 学内講師 2017: 奈良県立医科大学, 医学部附属病院, 研究員 2017: 奈良県立医科大学, 精神医学講座, 学内講師 2015 – 2017: 奈良県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science
Keywords	Principal Investigator 認知機能障害 / 統合失調症 / 死後脳 / 視空間作業記憶 / 作業記憶 / 前頭前野 / GPCRシグナル / 感情制御 / 気分障害 / 感情認知バイアス … More / 機能的MRI / 統合失調症スペクトラム / GPCR / 精神病スペクトラム障害 / OXPHOS / 作業記憶ネットワーク / 国際共同研究 / アクチン動態 / 樹状突起スパイン / 酸化的リン酸化 / ミトコンドリア / 死後脳解析 / トランスレーショナルリサーチ / 死後脳研究 / 細胞骨格 / 棘突起（スパイン） / アクチン細胞骨格 / 脳神経スパイン / staufen2 / RNA結合タンパク質 / 神経活動依存性発現遺伝子 / 抑制性神経伝達 / ネグレクト / 社会的隔離 / パルブアルブミン / 神経活動依存性 / 社会経験 … More Except Principal Investigator 死後脳 / 前頭前野 / 背外側前頭前野 / 錐体ニューロン / 自閉スペクトラム症 / ミエリン / MCI / 脳画像 / 慢性炎症 / フレイル / メタボ / 脳磁図 / 認知機能課題 / GABA / 認知機能 / GABAニューロン / 感情認知バイアス / ミクログリア / サイトカイン / TNF-α / マクロファージ / 発達 / 霊長類モデル / 死後脳研究 / 遺伝子発現 / ヒト死後脳 / 血管作動性腸管ペプチド / ネットワーク / 作業記憶 / μオピオイド受容体 / アクチン関連 / ソマトスタチン / パルブアルブミン / トランスレーショナルリサーチ / 分子神経免疫 / 神経性無食欲症 / 神経炎症 / ERP / 腸内フローラ / 糞便移植 / 思春期やせ症 / 近赤外線スペクトロスコピィ / 事象関連電位 / 摂食障害 / 思春期 / ユースメンタルヘルス / 脳腸相関 / 思春期メンタルヘルス / 神経性やせ症 / 恐怖記憶 / 前頭前野機能 / 自閉症 / 認知リハビリテーション / MRI / 社会的経験 / 髄鞘形成 / 社会性 / リハビリテーション / 小児期体験 / 海馬 / 隔離飼育 / クプリゾン / オリゴデンドロサイト / シナプス Less

統合失調症の作業記憶ネットワークにおける神経活動依存性遺伝子の発現解析
- Principal Investigator
  
  坪本真
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kanazawa University
Investigation of neural Basis of working memory and emotional regulation impairments in schizophrenia and mood disorders focused on GPCR signalingPrincipal Investigator
- Principal Investigator
  
  紀本創兵
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Wakayama Medical University
メタボ・フレイルによる慢性炎症と脳画像によるMCIの認知症への移行指標の確立
- Principal Investigator
  
  山田信一
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Wakayama Medical University
統合失調症と気分障害における感情制御ネットワーク障害のニューロンメカニズム
- Principal Investigator
  
  橋本隆紀
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kanazawa University
Research focusing on macrophage dysfunction in autism spectrum disorders
- Principal Investigator
  
  YAMAUCHI Takahira
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
Involvement of mitochondrial dysfunction in disrupted oscillatory brain activity in relation to cognitive deficits with schizophrenia.Principal Investigator
- Principal Investigator
  
  KIMOTO SOHEI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Wakayama Medical University
  Nara Medical University
Relationship between myu-opioid receptor and neuronal alterations in the prefrontal cortex of subjects with schizophrenia
- Principal Investigator
  
  Hashimoto Takanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Kanazawa University
Identification of the psychobiotics in young patients with anorexia nervosa by multidimensional analysis: Toward the discovery of therapeutic agents
- Principal Investigator
  
  Toshifumi Kishimoto
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Nara Medical University
注意欠如多動症と自閉スペクトラム症併存の神経基盤の解明と治療効果予測を目指して
- Principal Investigator
  
  山室和彦
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Exploration of the regulatory mechanism of RNA binding protein for the dendritic spine pathology in schizophreniaPrincipal Investigator
- Principal Investigator
  
  KIMOTO Sohei
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Dissecting the prefrontal cortex dysfunction and its recovery in autism spectrum disorder.
- Principal Investigator
  
  Makinodan Manabu
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Social experience-dependent myelination in the mPFC and its relevant synapse formation
- Principal Investigator
  
  Makinodan Manabu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University
Investigation of the molecular basis for social experience-depencent neural development in prefrotal cortexPrincipal Investigator
- Principal Investigator
  
  KIMOTO SOHEI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Nara Medical University

All 2024 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 精神医学領域の論文を読みこなすキーワード100!2022
- Author(s)
  紀本創兵（分担執筆：編集, 鬼塚俊明、橋本亮太）
- Total Pages
  280
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-20K07949
[Journal Article] Aberrant brain dynamics of large-scale functional networks across schizophrenia and mood disorder2024
- Author(s)
  Ishida Takuya、Yamada Shinichi、Yasuda Kasumi、Uenishi Shinya、Tamaki Atsushi、Tabata Michiyo、Ikeda Natsuko、Takahashi Shun、Kimoto Sohei
- Journal Title
  
  NeuroImage: Clinical
  
  Volume: 41 Pages: 103574-103574
- DOI
  10.1016/j.nicl.2024.103574
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07484, KAKENHI-PROJECT-23K06992, KAKENHI-PROJECT-23K27532
[Journal Article] Expression of actin- and oxidative phosphorylation-related transcripts across the cortical visuospatial working memory network in unaffected comparison and schizophrenia subjects.2022
- Author(s)
  Kimoto S, Hashimoto T, Berry KJ, Tsubomoto M, Yamaguchi Y, Enwright JF, Chen K, Kawabata R, Kikuchi M, Kishimoto T, Lewis DA.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: - Issue: 12 Pages: 2061-2070
- DOI
  10.1038/s41386-022-01274-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07949, KAKENHI-PROJECT-19H03580
[Journal Article] Tumor necrosis factor-α expression aberration of M1/M2 macrophages in adult high-functioning autism spectrum disorder.2021
- Author(s)
  Yamauchi T, Makinodan M, Toritsuka M, Okumura K, Kayashima Y, Ishida R, Kishimoto N, Takahashi M, Komori T, Yamaguchi Y, Takada R, Yamamuro K, Kimoto S, Yasuda Y, Hashimoto R, Kishimoto T
- Journal Title
  
  Autism Research
  
  Volume: 14 Issue: 11 Pages: 2330-2341
- DOI
  10.1002/aur.2585
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18K07609
[Journal Article] 腸内細菌-腸管-脳軸と児童青年の精神活動　脳-腸-微生物円環からみた思春期やせ症2020
- Author(s)
  紀本創兵、山口泰成、中野章代、矢野寿一、岸本年史
- Journal Title
  
  児童青年精神医学とその近接領域
  
  Volume: 61 Pages: 422-427
- Data Source
  KAKENHI-PROJECT-18H02754
[Journal Article] Delayed Prefrontal Hemodynamic Response Associated With Suicide Risk in Autism Spectrum Disorder2020
- Author(s)
  Ota T, Iida J, Okazaki K, Ishida R, Takahashi M, Okamura K, Yamamuro K, Kishimoto N, Kimoto S, Yasuda Y, Hashimoto R, Makinodan M, Kishimoto T.
- Journal Title
  
  Psychiatry Res
  
  Volume: 289 Pages: 112971-112971
- DOI
  10.1016/j.psychres.2020.112971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17068, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18KT0022
[Journal Article] Anti-inflammatory Effect of Ghrelin in Lymphoblastoid Cell Lines From Children With Autism Spectrum Disorder2019
- Author(s)
  Yamashita Yasunori、Makinodan Manabu、Toritsuka Michihiro、Yamauchi Takahira、Ikawa Daisuke、Kimoto Sohei、Komori Takashi、Takada Ryohei、Kayashima Yoshinori、Hamano-Iwasa Kaori、Tsujii Masatsugu、Matsuzaki Hideo、Kishimoto Toshifumi
- Journal Title
  
  Frontiers in Psychiatry
  
  Volume: 10 Pages: 152-152
- DOI
  10.3389/fpsyt.2019.00152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05373, KAKENHI-PROJECT-16H05377
[Journal Article] Altered gene expression in lymphoblastoid cell lines after subculture.2018
- Author(s)
  Toritsuka M, Makinodan M, Yamauchi T, Yamashita Y, Ikawa D, Komori T, Kimoto S, Hamano-Iwasa K, Matsuzaki H, Kishimoto T.
- Journal Title
  
  In Vitro Cell. Dev. Biol. Anim.
  
  Volume: 54 Issue: 7 Pages: 523-527
- DOI
  10.1007/s11626-018-0267-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05373, KAKENHI-PROJECT-16H05377
[Journal Article] Effects of cross-rearing with social peers on myelination in the medial prefrontal cortex of a mouse model with autism spectrum disorder2017
- Author(s)
  Makinodan M. Okumura K. Ikawa D. Yamashita Y. Yamamuro K. Toritsuka M. Kimoto S. Yamauchi T. Komori T. Kayashima Y. Yoshino H. Wanaka A. Kishimoto T.
- Journal Title
  
  Heliyon
  
  Volume: 3 Issue: 11 Pages: e00468-e00468
- DOI
  10.1016/j.heliyon.2017.e00468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Journal Article] Effects of the mode of re-socialization after juvenile social isolation on medial prefrontal cortex myelination and function2017
- Author(s)
  Makinodan M. Ikawa D. Yamamuro K. Yamashita Y. Torituka M. Kimoto S. Okumura K. Komori T. Fukami S. Yoshino H. Kanba S. Wanaka A. Kishimoto T
- Journal Title
  
  Sci.Rep
  
  Volume: 14 Issue: 1 Pages: 5481-5481
- DOI
  10.1038/s41598-017-05632-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10339, KAKENHI-PROJECT-15K15432, KAKENHI-PROJECT-16H05377, KAKENHI-PROJECT-15K14354
[Presentation] 軽度認知障害におけるメタボ・痩せと認知機能の関連2024
- Author(s)
  平田真之将、田畑倫代、山田信一、紀本創兵
- Organizer
  第120回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07020
[Presentation] 動物モデルおよびヒト死後脳解析からみた統合失調症の認知機能障害の分子基盤2022
- Author(s)
  紀本創兵
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-20K07949
[Presentation] Tumor necrosis factor-α expression aberration of M1/M2 macrophages in adult high-functioning autism spectrum disorder2022
- Author(s)
  Takahira Yamauchi, Michihiro Toritsuka, Kazuki Okumura, Yoshinori Kayashima, Rio Ishida, Takashi Komori, Yasunari Yamaguchi, Ryohei Takada, Kazuhiko Yamamuro, Sohei Kimoto, Toshifumi Kishimoto, Manabu Makinodan
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-18K07609
[Presentation] 健常対象者と統合失調症患者の死後脳における視空間作業記憶ネットワーク回路におけるアクチン関連およびOXPHOS関連遺伝子の発現解析2021
- Author(s)
  紀本創兵, 橋本隆紀, 坪本真, 山口泰成, 岸本年史, David A. Lewis
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K07949
[Presentation] 統合失調症の大脳皮質ニューロンの変化とそのメカニズム－前頭前野の錐体ニューロンにおける分子発現の変化からみた統合失調症の認知機能障害生物基盤2021
- Author(s)
  紀本創兵
- Organizer
  第117回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07949
[Presentation] P300を用いた思春期神経性無食欲症における認知機能の評価2020
- Author(s)
  岡崎康輔、山室和彦、紀本創兵、長濱剛史、疇地崇広、山口泰成、松浦広樹、岸本直子、岸本直子、太田豊作、飯田順三
- Organizer
  第61回日本児童青年精神医学会総会
- Data Source
  KAKENHI-PROJECT-18H02754
[Presentation] 統合失調症の作業記憶神経ネットワークにおける興奮性と抑制性神経の機能を制御する遺伝子の発現変化2020
- Author(s)
  紀本創兵、橋本隆紀、川端梨加、坪本真、岸本年史、David A. Lewis
- Organizer
  第15回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-20K07949
[Presentation] 死後脳研究から考える統合失調症の認知機能障害とE-I balance変化の分子基盤2018
- Author(s)
  紀本　創兵
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会合同年会
- Data Source
  KAKENHI-PROJECT-17K16394
[Presentation] Expression of Stau2-Regulated Transcripts Across the Cortical Visuospatial Working Memory Network in Schizophrenia2018
- Author(s)
  Sohei Kimoto, Takanori Hashimoto, Makoto Tsubomoto, Yasunari Yamaguchi, Rika Kawabata, Toshifumi Kishimoto and David A. Lewis
- Organizer
  Society of Biological Psychiatry 73rd Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16394
[Presentation] Lower expression of regulator of G protein signaling 4 in schizophrenia: contribution of altered cortical excitation-inhibition balance2017
- Author(s)
  紀本創兵, 山口泰成, 岸本年史
- Organizer
  第60回日本神経化学会
- Data Source
  KAKENHI-PROJECT-17K16394
[Presentation] 認知機能障害の神経基盤に対する神経活動依存性に発現される遺伝子群の寄与2016
- Author(s)
  紀本創兵
- Organizer
  第38回日本生物学的精神医学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K19742
[Presentation] Altered markers of cortical GABA neuronal activity in schizophrenia:Role of NARP2016
- Author(s)
  紀本創兵
- Organizer
  第14回アジア太平洋神経化学大会
- Place of Presentation
  マレーシア　クアランプール
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-15K19742

1. Hashimoto Takanori (40249959)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
2. Makinodan Manabu (00510182)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 太田豊作 (10553646)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 鳥塚通弘 (20588529)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. YAMAUCHI Takahira (20550817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 井川大輔 (00526717)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 山室和彦 (60526721)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 松岡究 (80613794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 芳野浩樹 (10347560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 坪本真 (40835906)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 山田信一 (70549716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. Toshifumi Kishimoto (60201456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 深見伸一 (90424150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 安野史彦 (60373388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松田康裕 (70445063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮坂俊輝 (00771023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 北村聡一郎 (10714389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 矢野寿一 (20374944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 菊知充 (00377384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 廣澤徹 (80645127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石田卓也 (10549728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. 岡村和哉 (20635734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 松浦広樹 (70613793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TAKAHASHI Shun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 池田俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 松崎伸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 松崎秀夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 高田昌彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimoto Sohei 紀本 創兵

KIMOTO SOHEI 紀本 創兵

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Co-Researchers

Principal Investigator

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Investigation of neural Basis of working memory and emotional regulation impairments in schizophrenia and mood disorders focused on GPCR signalingPrincipal Investigator

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Involvement of mitochondrial dysfunction in disrupted oscillatory brain activity in relation to cognitive deficits with schizophrenia.Principal Investigator

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Exploration of the regulatory mechanism of RNA binding protein for the dendritic spine pathology in schizophreniaPrincipal Investigator

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Investigation of the molecular basis for social experience-depencent neural development in prefrotal cortexPrincipal Investigator

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Research Field

Research Institution

[Book] 精神医学領域の論文を読みこなすキーワード100!2022

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[Journal Article] Aberrant brain dynamics of large-scale functional networks across schizophrenia and mood disorder2024

Kimoto Sohei 紀本創兵

KIMOTO SOHEI 紀本創兵

[Journal Article] 腸内細菌-腸管-脳軸と児童青年の精神活動　脳-腸-微生物円環からみた思春期やせ症2020