Higo Shuichiro 肥後修一朗

… Alternative Names

HIGO Schuichiro 肥後修一朗

KATO Hisakazu 加藤久和

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Researcher Number	00604034
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 大阪大学, 大学院医学系研究科, 講師 2022: 大阪大学, 大学院医学系研究科, 特任准教授(常勤) 2020 – 2021: 大阪大学, 医学系研究科, 特任准教授(常勤) 2018 – 2019: 大阪大学, 医学系研究科, 寄附講座准教授 2016 – 2017: 大阪大学, 医学系研究科, 助教 … More 2014 – 2016: 大阪大学, 大学院医学系研究科, 助教 2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2014: 大阪大学, 医学系研究科 2013: 大阪大学, 医学(系)研究科(研究院), 寄附講座助教 2012: 大阪大学, 医学部附属病院, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine Except Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields / Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine
Keywords	Principal Investigator 心不全 / 疾患iPS細胞 / ゲノム編集 / 高速シークエンサー / 不整脈原性心筋症 / デスモゾーム / 肥大型心筋症 / 循環器 / 相同組み換え / 心筋細胞 … More / 拡張型心筋症 / 心筋症 / 線維芽細胞 / トランスオミクス / 心臓リモデリング / 次世代シークエンサー / エピゲノム … More Except Principal Investigator 疾患iPS細胞 / 心筋症 / iPS細胞 / ゲノム編集 / 心不全 / ゲノム医療 / 不整脈原性心筋症 / 肥大型心筋症 / エネルギー代謝 / 太いフィラメント / 心筋サルコメア / 希少心筋症 / 心筋不全 / バイオマーカー / ディープフェノタイピング / 不整脈源性右室心筋症 / 遺伝子治療 / 難治性心筋症 / 循環器内科学 / 細胞間接着 / 病態モデル / デスモゾーム / 拡張型心筋症 / 細胞遊走 / Pdlim5 / AMPキナーゼ / ｃｅｌｌ　ｍｉｇｒａｔｉｏｎ / ＡＭＰＫ / cell migration / PDLIM5 / AMPK / 循環器・高血圧 / モデル動物 / 利尿ホルモン / アポトーシス / 心筋肥大 / NF-kB / MAPキナーゼ / ST2受容体 / IL-33 / G蛋白共役性受容体 / 心筋細胞 / 心筋リモデリング / G蛋白共役受容体 / 内因性免疫 / 心筋保護 / 自然免疫 / 慢性心不全 / 臨床循環器 / 分子循環器病学 / 難治性心不全 / 細胞核クロマチン / エピゲノム / ジスルフィド結合 / 低酸素 / 腹部大動脈瘤 / 小胞体ストレス Less

太いフィラメントに基づくサルコメア制御機構の心筋エネルギー代謝における役割
- Principal Investigator
  
  塚本蔵
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hyogo Medical University
Stratification of myocardial failure and development of genomic medicine
- Principal Investigator
  
  坂田泰史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Development of interventional therapy for desmosomal cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  肥後修一朗
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Elucidation of the mechanism of cardiomyocyte-autonomous fibrosis in rare cardiomyopathies and establishment of a genomic medicine framework
- Principal Investigator
  
  坂田泰史
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
重症心不全に潜む不整脈源性心筋症を診断するバイオマーカーの開発
- Principal Investigator
  
  坂田泰史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Development of clinical practice for rare intractable cardiomyopathy using deep phenotyping combined with iPS cell technology
- Principal Investigator
  
  Yasushi Sakata
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Development of Human Disease Model of Arrhythmogenic Right Ventricular Cardiomyopathy for Personalized Medicine
- Principal Investigator
  
  Sakata Yasushi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Therapeutic development targeting molecular basis of dilated-phase hypertrophic cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  Higo Shuichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Clarification of molecular pathophysiology and identification of therapeutic target in desmosome-related cardiomyopathy
- Principal Investigator
  
  Hikoso Shungo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Development of upstream therapy targeting molecular basis of refractory cardiomyopathy
- Principal Investigator
  
  Sakata Yasushi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Therapeutic Application of Genome Editing for Advanced Heart FailurePrincipal Investigator
- Principal Investigator
  
  Shuichiro Higo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Development of simple and noninvasive method to assess the severity of heart failure
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Molecular discovery research targeting cardiac remodeling using multi-directional transcriptional profiling and therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  Higo Shuichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
anti-atherosclerotic and anti-cancer effects of AMPK activation
- Principal Investigator
  
  Tsukamoto Osamu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Exploration for Aggravating Process of Heart Failure Induced by Specific Interaction with G-protein-coupled Receptor and Toll-like Receptor
- Principal Investigator
  
  Sanada Shoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Role of ER oxidoreductin-1 in cardiovascular remodeling
- Principal Investigator
  
  MINAMINO TETSUO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
A New Diagnostics Method for Refractory Heart Failure
- Principal Investigator
  
  ASANO YOSHIHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Quantitative Epigenome Mapping to Identify Therapeutic Target in Heart FailurePrincipal Investigator
- Principal Investigator
  
  HIGO Shuichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] 非分裂心筋細胞のゲノム編集と難治性心筋症への治療介入2023
- Author(s)
  肥後修一朗
- Total Pages
  605
- Publisher
  技術情報協会　ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
- ISBN
  9784861049781
- Data Source
  KAKENHI-PROJECT-21H02915
[Book] 非分裂心筋細胞のゲノム編集と難治性心筋症への治療介入2023
- Author(s)
  肥後修一朗
- Total Pages
  605
- Publisher
  技術情報協会　ゲノム編集の最新技術と医薬品・遺伝子治療・農業・水畜産物・有用物質生産への活用
- Data Source
  KAKENHI-PROJECT-22K19526
[Book] Heart View 疾患iPS細胞を用いた心筋症個別化医療へのアプローチ2022
- Author(s)
  肥後　修一朗
- Publisher
  MEDICAL VIEW
- Data Source
  KAKENHI-PROJECT-21H02915
[Book] Heart View 疾患iPS細胞を用いた心筋症個別化医療へのアプローチ2022
- Author(s)
  肥後　修一朗
- Publisher
  MEDICAL VIEW
- Data Source
  KAKENHI-PROJECT-19K08489
[Book] Heart View 疾患iPS細胞を用いた心筋症個別化医療へのアプローチ2022
- Author(s)
  肥後　修一朗
- Publisher
  MEDICAL VIEW
- Data Source
  KAKENHI-PROJECT-20K21602
[Book] 医学のあゆみ2021
- Author(s)
  肥後修一朗
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-19K08489
[Book] 医学のあゆみ2021
- Author(s)
  肥後修一朗
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20K21602
[Book] 心不全のサイエンス　ゲノム編集の難治性心筋症医療応用2019
- Author(s)
  肥後修一朗
- Total Pages
  216
- Publisher
  羊土社
- ISBN
  9784758103770
- Data Source
  KAKENHI-PROJECT-16K09500
[Book] 心不全のサイエンス　ゲノム編集の難治性心筋症医療応用2019
- Author(s)
  肥後修一朗
- Total Pages
  216
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18K19543
[Book] 医療応用をめざすゲノム編集　拡張型心筋症におけるゲノム編集治療2018
- Author(s)
  肥後修一朗
- Total Pages
  274
- Publisher
  化学同人
- ISBN
  9784759817294
- Data Source
  KAKENHI-PROJECT-16K09500
[Book] 心不全　ゲノム編集2018
- Author(s)
  肥後修一朗, 石津宜丸, 坂田泰史
- Total Pages
  720
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-16K09500
[Book] 心不全　ゲノム編集2018
- Author(s)
  肥後修一朗, 石津宜丸, 坂田泰史
- Total Pages
  720
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-18K19543
[Journal Article] SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes2023
- Author(s)
  Okuno Shota、Higo Shuichiro、Kondo Takumi、Shiba Mikio、Kameda Satoshi、Inoue Hiroyuki、Tabata Tomoka、Ogawa Shou、Morishita Yu、Sun Congcong、Ishino Saki、Honda Tomoyuki、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 21397-21397
- DOI
  10.1038/s41598-023-48084-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19436, KAKENHI-PROJECT-22K19526, KAKENHI-PROJECT-21H02738, KAKENHI-PROJECT-21H02915
[Journal Article] End-stage Hypertrophic Cardiomyopathy with Advanced Heart Failure in Patients Carrying <i>MYH7</i> R453 Variants: A Case Series2023
- Author(s)
  Naito Susumu、Higo Shuichiro、Kameda Satoshi、Ogawa Shou、Tabata Tomoka、Akazawa Yasuhiro、Nakamura Daisuke、Nakamoto Kei、Sera Fusako、Kuramoto Yuki、Aasano Yoshihiro、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 21 Pages: 3167-3173
- DOI
  10.2169/internalmedicine.1497-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02915
[Journal Article] Disease modeling of desmosome-related cardiomyopathy using induced pluripotent stem cell-derived cardiomyocytes2023
- Author(s)
  Higo Shuichiro
- Journal Title
  
  World Journal of Stem Cells
  
  Volume: 15 Issue: 3 Pages: 71-82
- DOI
  10.4252/wjsc.v15.i3.71
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-22K19526
[Journal Article] Tenascin-C as a potential marker for immunohistopathology of doxorubicin-induced cardiomyopathy2023
- Author(s)
  Nishikawa Tatsuya、Shiba Mikio、Ikeda Yoshihiko、Ohta-Ogo Keiko、Kondo Takumi、Tabata Tomoka、Oka Toru、Shioyama Wataru、Yamamoto Hironori、Yasui Taku、Higuchi Yoshiharu、Ishibashi-Ueda Hatsue、Honma Keiichiro、Izumi Chisato、Higo Shuichiro、Hatakeyama Kinta、Sakata Yasushi、Fujita Masashi
- Journal Title
  
  European Heart Journal Open
  
  Volume: 3 Issue: 5 Pages: 1-12
- DOI
  10.1093/ehjopen/oead104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06941, KAKENHI-PROJECT-21H02915
[Journal Article] Modeling Reduced Contractility and Stiffness Using iPSC-Derived Cardiomyocytes Generated From Female Becker Muscular Dystrophy Carrier2023
- Author(s)
  Kameda Satoshi、Higo Shuichiro、Shiba Mikio、Kondo Takumi、Li Junjun、Liu Li、Tabata Tomoka、Inoue Hiroyuki、Okuno Shota、Ogawa Shou、Kuramoto Yuki、Yasutake Hideki、Lee Jong-Kook、Takashima Seiji、Ikeda Yoshihiko、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: - Issue: 6 Pages: 599-613
- DOI
  10.1016/j.jacbts.2022.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19526, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-21H02914
[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022
- Author(s)
  Tabata Tomoka、Kuramoto Yuki、Ohtani Tomohito、Miyawaki Hiroshi、Miyashita Yohei、Sera Fusako、Kioka Hidetaka、Higo Shuichiro、Asano Yoshihiro、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 13 Pages: 1987-1993
- DOI
  10.2169/internalmedicine.8594-21
- NAID
  130008130223
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-23K24328, KAKENHI-PROJECT-19H03652
[Journal Article] Modeling reduced contractility and impaired desmosome assembly due to plakophilin-2 deficiency using isogenic iPS cell-derived cardiomyocytes2022
- Author(s)
  Inoue Hiroyuki、Nakamura Satoki、Higo Shuichiro、Shiba Mikio、Kohama Yasuaki、Kondo Takumi、Kameda Satoshi、Tabata Tomoka、Okuno Shota、Ikeda Yoshihiko、Li Junjun、Liu Li、Yamazaki Satoru、Takeda Maki、Ito Emiko、Takashima Seiji、Miyagawa Shigeru、Sawa Yoshiki、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 17 Issue: 2 Pages: 337-351
- DOI
  10.1016/j.stemcr.2021.12.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-21H02915
[Journal Article] Human-Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for TNNT2 Δ160E-Induced Cardiomyopathy2022
- Author(s)
  Kondo Takumi、Higo Shuichiro、Shiba Mikio、Kohama Yasuaki、Kameda Satoshi、Tabata Tomoka、Inoue Hiroyuki、Okuno Shota、Ogawa Shou、Nakamura Satoki、Takeda Maki、Ito Emiko、Li Junjun、Liu Li、Kuramoto Yuki、Lee Jong-Kook、Takashima Seiji、Miyagawa Shigeru、Sawa Yoshiki、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Circulation: Genomic and Precision Medicine
  
  Volume: 15 Issue: 5 Pages: 429-443
- DOI
  10.1161/circgen.121.003522
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-21H03808
[Journal Article] Multiplexed measurement of cell type-specific calcium kinetics using high-content image analysis combined with targeted gene disruption2022
- Author(s)
  Tabata Tomoka、Masumura Yuki、Higo Shuichiro、Kunimatsu Suzuka、Kameda Satoshi、Inoue Hiroyuki、Okuno Shota、Ogawa Shou、Takashima Seiji、Watanabe Mikio、Miyagawa Shigeru、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 40-49
- DOI
  10.1016/j.bbrc.2022.10.088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19526, KAKENHI-PROJECT-19H04048, KAKENHI-PROJECT-21H02915
[Journal Article] Genome Editing in Human Induced Pluripotent Stem Cells (hiPSCs)2021
- Author(s)
  Higo Shuichiro、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  Methods Mol Biol
  
  Volume: - Pages: 235-245
- DOI
  10.1007/978-1-0716-1484-6_21
- ISBN
  9781071614839, 9781071614846
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915
[Journal Article] Phenotypic recapitulation and correction of desmoglein-2-deficient cardiomyopathy using human-induced pluripotent stem cell-derived cardiomyocytes2021
- Author(s)
  Shiba Mikio、Higo Shuichiro、Kondo Takumi、Li Junjun、Liu Li、Ikeda Yoshihiko、Kohama Yasuaki、Kameda Satoshi、Tabata Tomoka、Inoue Hiroyuki、Nakamura Satoki、Takeda Maki、Ito Emiko、Takashima Seiji、Miyagawa Shigeru、Sawa Yoshiki、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 15 Pages: 1384-1397
- DOI
  10.1093/hmg/ddab127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915
[Journal Article] Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes2020
- Author(s)
  Kohama Yasuaki、Higo Shuichiro、Masumura Yuki、Shiba Mikio、Kondo Takumi、Ishizu Takamaru、Higo Tomoaki、Nakamura Satoki、Kameda Satoshi、Tabata Tomoka、Inoue Hiroyuki、Motooka Daisuke、Okuzaki Daisuke、Takashima Seiji、Miyagawa Shigeru、Sawa Yoshiki、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 15348-15348
- DOI
  10.1038/s41598-020-72216-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K08356, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-18K08069, KAKENHI-PROJECT-19K16518
[Journal Article] Old-Age Onset Progressive Cardiac Contractile Dysfunction in a Patient with Polycystic Kidney Disease Harboring a <i>PKD1</i> Frameshift Mutation2019
- Author(s)
  Suwa Yoshinobu、Higo Shuichiro、Nakamoto Kei、Sera Fusako、Kunimatsu Suzuka、Masumura Yuki、Kanzaki Machiko、Mizote Isamu、Mizuno Hiroya、Fujio Yasushi、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 1 Pages: 220-225
- DOI
  10.1536/ihj.18-184
- NAID
  130007557187
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-01-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19543, KAKENHI-PROJECT-18K19545, KAKENHI-PROJECT-18K15848, KAKENHI-PROJECT-18H02603, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-17K16004
[Journal Article] Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction2019
- Author(s)
  Shibamoto Masato、Higo Tomoaki、Naito Atsuhiko T.、Nakagawa Akito、Sumida Tomokazu、Okada Katsuki、Sakai Taku、Kuramoto Yuki、Yamaguchi Toshihiro、Ito Masamichi、Masumura Yuki、Higo Shuichirou、Lee Jong-Kook、Hikoso Shungo、Komuro Issei、Sakata Yasushi
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 4 Pages: 944-957
- DOI
  10.1536/ihj.18-701
- NAID
  130007684141
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-07-30
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03662, KAKENHI-PROJECT-18K19543, KAKENHI-PROJECT-19K08489
[Journal Article] Targeted Genome Replacement via Homology-directed Repair in Non-dividing Cardiomyocytes2017
- Author(s)
  Ishizu T, Higo S, Masumura Y, Kohama Y, Shiba M, Higo T, Shibamoto M, Nakagawa A, Morimoto S, Takashima S, Hikoso S, Sakata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 9363-9363
- DOI
  10.1038/s41598-017-09716-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08514, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-17K08540, KAKENHI-PROJECT-17K16004, KAKENHI-PROJECT-15H04820
[Journal Article] A Development of Nucleic Chromatin Measurements as a New Prognostic Marker for Severe Chronic Heart Failure.2016
- Author(s)
  Kanzaki M, Asano Y, Ishibashi-Ueda H, Oiki E, Nishida T, Asanuma H, Kato H, Oka T, Ohtani T, Tsukamoto O, Higo S, Kioka H, Matsuoka K, Sawa Y, Komuro I, Kitakaze M, Takashima S, Sakata Y.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 2 Pages: e0148209-e0148209
- DOI
  10.1371/journal.pone.0148209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K09139
[Journal Article] Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.2016
- Author(s)
  Masumura Y, Higo S, Asano Y, Kato H, Yan Y, Ishino S, Tsukamoto O, Kioka H, Hayashi T, Shintani Y, Yamazaki S, Minamino T, Kitakaze M, Komuro I, Takashima S, Sakata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 28592-28592
- DOI
  10.1038/srep28592
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15K08271, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-16K09501
[Journal Article] Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5.2015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 6137-6137
- DOI
  10.1038/ncomms7137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-25461119
[Journal Article] Higdla is a oositive regulaator of cytochrome c oxidase2015
- Author(s)
  T. Hayashi, Y. Asano, Y. Shintani, H. Aoyama, H. Kioka, O. Tsukamoto, M. Hikita, K. Shinzawa-Itoh, K. Takajuji, S. Higo, H. Kato, S. Yamazaki, K. Matsuoka, A. Nakano, H. Asanuma, M. Asakura, T. Minamino, Y. Goto, T. Ogura, M. Kitakaze, I. Komuro, Y. Sakata, T. Tsukihara, S. Yoshikawa, S. Takashima
- Journal Title
  
  Proc. Nat. Acad. Sci. U.S.A.
  
  Volume: 112 Issue: 5 Pages: 1553-1558
- DOI
  10.1073/pnas.1419767112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PUBLICLY-25109540, KAKENHI-PROJECT-25860599, KAKENHI-PUBLICLY-26104532, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26670402, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-25461119
[Journal Article] Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5.2015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S..
- Journal Title
  
  Nat Commun.
  
  Volume: 30 Pages: 6137-6150
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670402
[Journal Article] Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart.2014
- Author(s)
  Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S.
- Journal Title
  
  FASEB J.
  
  Volume: 28(4) Issue: 4 Pages: 1870-9
- DOI
  10.1096/fj.13-245522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25118709, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26860559
[Journal Article] Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA2.2014
- Author(s)
  Shintani Y, Drexler HC, Kioka H, Terracciano CM, Coppen SR, Imamura H, Akao M, Nakai J, Wheeler AP, Higo S, Nakayama H, Takashima S, Yashiro K, Suzuki K.
- Journal Title
  
  EMBO Reports
  
  Volume: 15 Issue: 4 Pages: 438-445
- DOI
  10.1002/embr.201337945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390212, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25111703, KAKENHI-PROJECT-25461346, KAKENHI-PROJECT-25670387, KAKENHI-PUBLICLY-26115504, KAKENHI-PROJECT-26291027, KAKENHI-PROJECT-26560456, KAKENHI-PROJECT-26860559
[Journal Article] Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart2014
- Author(s)
  Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S
- Journal Title
  
  FASEB J
  
  Volume: 28(4) Pages: 1870-9
- Data Source
  KAKENHI-PROJECT-24790757
[Journal Article] Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2014
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Takafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y, Takashima S.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 111(1) Pages: 7-7
- Data Source
  KAKENHI-PROJECT-24790757
[Journal Article] Toll-like receptor 9 protects non-immune cells from stress by modulating mitochondrial ATP synthesis through the inhibition of SERCA22014
- Author(s)
  Shintani Y, Drexler HC, Kioka H, Terracciano CM, Coppen SR, Imamura H, Akao M, Nakai J, Wheeler AP, Higo S, Nakayama H, Takashima S, Yashiro K, Suzuki K
- Journal Title
  
  EMBO Rep
  
  Pages: 7-7
- Data Source
  KAKENHI-PROJECT-24790757
[Journal Article] Evaluation of intra-mitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2013
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Tkafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y and Takashima S
- Journal Title
  
  PNAS
  
  Volume: 111 Issue: 1 Pages: 273-278
- DOI
  10.1073/pnas.1318547111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24570149, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PROJECT-24790917, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25461119, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26461108
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer.2012
- Author(s)
  K. Nishikawa, T. Asai, H. Shigematsu, K. Shimizu, H. Kato, Y. Asano, S. Takashima, E. Mekada, N. Oku, T. Minamino
- Journal Title
  
  J. Control. Release
  
  Volume: 160 Issue: 2 Pages: 274-280
- DOI
  10.1016/j.jconrel.2011.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-22890104, KAKENHI-PROJECT-23240126, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Patent] 不整脈源性心筋症患者由来の多能性幹細胞およびその利用ならびに不整脈源性心筋症治療用医薬2020
- Inventor(s)
  肥後修一朗, 彦惣俊吾, 宮川繁, 澤芳樹, 坂田泰史
- Industrial Property Rights Holder
  肥後修一朗, 彦惣俊吾, 宮川繁, 澤芳樹, 坂田泰史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-044996
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K08489
[Patent] 不整脈源性心筋症患者由来の多能性幹細胞およびその利用ならびに不整脈源性心筋症治療用医薬2020
- Inventor(s)
  肥後修一朗, 彦惣俊吾, 宮川繁, 澤芳樹, 坂田泰史
- Industrial Property Rights Holder
  肥後修一朗, 彦惣俊吾, 宮川繁, 澤芳樹, 坂田泰史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-044996
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Elucidation of the pathological basis and therapeutic development for advanced heart failure using disease-specific iPS cell-derived cardiomyocytes2023
- Author(s)
  Shuichiro Higo
- Organizer
  Symposium, Genomic analysis and Genome editing, CVMW2023, The 7th JCS Council Forum on Basic Cardiovascular Research
- Invited
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] 個別化医療を目的とした難治性心筋症ヒト疾患モデル細胞の構築2023
- Author(s)
  肥後修一朗
- Organizer
  第27回日本心不全学会シンポジウム再生医療の進歩（疾患iPS を含む）
- Invited
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] 個別化医療を目的とした難治性心筋症ヒト疾患モデル細胞の構築2023
- Author(s)
  肥後修一朗
- Organizer
  第27回日本心不全学会シンポジウム再生医療の進歩（疾患iPS を含む）
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes2023
- Author(s)
  Shota Okuno, Shuichiro Higo, Satoshi Kameda, Tomoka Tabata, Shou Ogawa, Shigeru Miyagawa, Yasushi Sakata
- Organizer
  第27回日本心不全学会YIA基礎部門優秀賞
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Elucidation of the pathological basis and therapeutic development for advanced heart failure using disease-specific iPS cell-derived cardiomyocytes2023
- Author(s)
  Shuichiro Higo
- Organizer
  Symposium, Genomic analysis and Genome editing, CVMW2023, The 7th JCS Council Forum on Basic Cardiovascular Research
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Elucidation of the pathological basis and therapeutic development for advanced heart failure using disease-specific iPS cell-derived cardiomyocytes2023
- Author(s)
  Shuichiro Higo
- Organizer
  第97回日本薬理学会年会国際心臓研究学会日本部会(ISHR)共催シンポジウム「心不全研究の最前線から拓く治療戦略」
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 左室収縮能低下を伴う重症心不全に移行しMYH7 R453バリアントが同定された肥大型心筋症の3症例2023
- Author(s)
  内藤進, 肥後修一朗, 亀田聡士, 小川翔, 田端智香, 赤澤康裕, 中村大輔, 中本敬, 世良英子, 藏本勇希, 朝野仁裕, 彦惣俊吾, 宮川繁, 坂田泰史
- Organizer
  第9回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Elucidation of the pathological basis and therapeutic development for advanced heart failure using disease-specific iPS cell-derived cardiomyocytes2023
- Author(s)
  Shuichiro Higo
- Organizer
  第97回日本薬理学会年会国際心臓研究学会日本部会(ISHR)共催シンポジウム「心不全研究の最前線から拓く治療戦略」
- Invited
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] SARS-CoV-2 spike receptor-binding domain is internalized and promotes protein ISGylation in human induced pluripotent stem cell-derived cardiomyocytes2023
- Author(s)
  Shota Okuno, Shuichiro Higo, Satoshi Kameda, Tomoka Tabata, Shou Ogawa, Shigeru Miyagawa, Yasushi Sakata
- Organizer
  第27回日本心不全学会YIA基礎部門優秀賞
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] Human iPSC-derived Closed-loop Cardiac Tissue for Improved Drug Assessment2023
- Author(s)
  Ying Hua, Junjun Li, Xiang Qu, Masako Ishida, Noriko Yoshida, Jingbo Zhang, Hayato Miyoshi, Mikio Shiba, Shuichiro Higo, Nagako Sougawa, Maki Takeda, Takuji Kawamura, Ryohei Matsuura, Toshihiko Toyofuku, Yoshiki Sawa, Li Liu, Shigeru Miyagawa
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] 左室収縮能低下を伴う重症心不全に移行しMYH7 R453バリアントが同定された肥大型心筋症の3症例2023
- Author(s)
  内藤進, 肥後修一朗, 亀田聡士, 小川翔, 田端智香, 赤澤康裕, 中村大輔, 中本敬, 世良英子, 藏本勇希, 朝野仁裕, 彦惣俊吾, 宮川繁, 坂田泰史
- Organizer
  第9回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] 不整脈原性心筋症iPS細胞由来分化心筋細胞を用いたプラコフィリン2欠損が細胞骨格に与える影響の検討2022
- Author(s)
  内藤進, 井上裕之, 肥後修一朗, 小川翔, 奥野翔太, 田端智香, 亀田聡士, 近藤匠巳, 坂田泰史
- Organizer
  第8回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 分子機能による難治性心筋症の層別化と病態解明2022
- Author(s)
  肥後修一朗
- Organizer
  第70回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] 分子機能による難治性心筋症の層別化と病態解明2022
- Author(s)
  肥後修一朗
- Organizer
  第70回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] ハイコンテントイメージングを用いた単一細胞カルシウム動態解析とゲノム編集への応用2022
- Author(s)
  羽白亮, 田端智香, 肥後修一朗, 近藤匠巳, 亀田聡士, 井上裕之, 奥野翔太, 小川翔, 坂田泰史
- Organizer
  第8回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 分子機能による層別化を目的とした心筋症疾患iPS細胞ライブラリーの構築2022
- Author(s)
  肥後修一朗, 木岡秀隆, 李鍾國, 彦惣俊吾, 朝野仁裕, 宮川繁, 坂田泰史
- Organizer
  第26回日本心不全学会学術集会シンポジウムゲノム情報を活かした心筋症医療
- Invited
- Data Source
  KAKENHI-PROJECT-22K19526
[Presentation] Modeling Reduced Contractility and Impaired Desmosome Assembly due to Plakophilin-2 Deficiency using Isogenic iPS Cell-Derived Cardiomyocytes2022
- Author(s)
  Hiroyuki Inoue,Satoki Nakamura,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Takumi Kondo,Satoshi Kameda,Tomoka Tabata,Shota Okuno,Yoshihiko Ikeda,Junjun Li,Li Liu,Satoru Yamazaki,Maki Takeda,Emiko Ito,Seiji Takashima,Shigeru Miyagwa,Sawa Yoshiki,Shungo Hikoso,Yasushi Sakata
- Organizer
  第86回日本循環器学会学術集会 YIA (Basic Research部門）優秀賞
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Modeling Reduced Contractility and Impaired Desmosome Assembly due to Plakophilin-2 Deficiency using Isogenic iPS Cell-Derived Cardiomyocytes2022
- Author(s)
  Hiroyuki Inoue,Satoki Nakamura,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Takumi Kondo,Satoshi Kameda,Tomoka Tabata,Shota Okuno,Yoshihiko Ikeda,Junjun Li,Li Liu,Satoru Yamazaki,Maki Takeda,Emiko Ito,Seiji Takashima,Shigeru Miyagwa,Sawa Yoshiki,Shungo Hikoso,Yasushi Sakata
- Organizer
  第86回日本循環器学会学術集会 YIA (Basic Research部門）優秀賞
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] iPS細胞由来分化心筋細胞を用いたBecker型筋ジストロフィー(BMD)心筋収縮力・剛性低下の再現と病態解明2022
- Author(s)
  亀田聡士, 肥後修一朗, 志波幹夫, 近藤匠巳, 李俊君, 劉莉, 田端智香, 井上裕之, 奥野翔太, 高島成二, 池田善彦, 彦惣俊吾, 宮川繁, 坂田泰史
- Organizer
  第8回日本心筋症研究会 YIA最優秀賞
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 分子機能による層別化を目的とした心筋症疾患iPS細胞ライブラリーの構築2022
- Author(s)
  肥後修一朗, 木岡秀隆, 李鍾國, 彦惣俊吾, 朝野仁裕, 宮川繁, 坂田泰史
- Organizer
  第26回日本心不全学会学術集会シンポジウムゲノム情報を活かした心筋症医療
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] ヒトiPS細胞由来分化心筋細胞を用いた不整脈原性心筋症の病態解明2022
- Author(s)
  肥後修一朗
- Organizer
  第8回日本心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Development of Personalized Medicine Targeting Arrhythmogenic Cardiomyopathy Concealed in Advanced Heart Failure2022
- Author(s)
  Shuichiro Higo
- Organizer
  第 86 回日本循環器学会学術集会幹細胞・遺伝子治療・心臓再生の最前線 Cutting-edge Science in Stem Cell, Gene Therapy, and Regeneration for Cardiovascular Disease
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] ドキソルビシン心筋症の病理学的診断におけるテネイシンC とマクロファージの有用性2022
- Author(s)
  西川達哉, 志波幹夫, 池田善彦, 近藤匠巳, 肥後修一朗, 安井琢, 岡亨, 泉知里, 植田初江, 畠山金太, 坂田泰史, 藤田雅史
- Organizer
  第5 回日本腫瘍循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Development of Personalized Medicine Targeting Arrhythmogenic Cardiomyopathy Concealed in Advanced Heart Failure2022
- Author(s)
  Shuichiro Higo
- Organizer
  第 86 回日本循環器学会学術集会幹細胞・遺伝子治療・心臓再生の最前線 Cutting-edge Science in Stem Cell, Gene Therapy, and Regeneration for Cardiovascular Disease
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Modeling Reduced Contractility and Impaired Desmosome Assembly due to Plakophilin-2 Deficiency using Isogenic iPS Cell-Derived Cardiomyocytes2022
- Author(s)
  Hiroyuki Inoue,Satoki Nakamura,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Takumi Kondo,Satoshi Kameda,Tomoka Tabata,Shota Okuno,Yoshihiko Ikeda,Junjun Li,Li Liu,Satoru Yamazaki,Maki Takeda,Emiko Ito,Seiji Takashima,Shigeru Miyagwa,Sawa Yoshiki,Shungo Hikoso,Yasushi Sakata
- Organizer
  第86回日本循環器学会学術集会 YIA (Basic Research部門）優秀賞
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Development of Personalized Medicine Targeting Arrhythmogenic Cardiomyopathy Concealed in Advanced Heart Failure2022
- Author(s)
  Shuichiro Higo
- Organizer
  第 86 回日本循環器学会学術集会幹細胞・遺伝子治療・心臓再生の最前線 Cutting-edge Science in Stem Cell, Gene Therapy, and Regeneration for Cardiovascular Disease
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] トロポニンTΔ160E変異を有するアイソジェニックiPS心筋を用いた拡張相肥大型心筋症の病態解明2021
- Author(s)
  近藤匠巳,肥後修一朗,志波幹夫,小濱康明,亀田聡士,田端智香,井上裕之,奥野翔太,武田真季,藏本勇希,李鍾國,高島成二,宮川繁,彦惣俊吾,坂田泰史
- Organizer
  第7回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] 悪性心室性頻拍と重症心不全を特徴とする日本におけるホスホランバン p.Arg14del心筋症の臨床像2021
- Author(s)
  田端智香,藏本勇希,大谷朋仁,宮脇大,宮下洋平,世良英子,木岡秀隆,肥後修一朗,朝野仁裕,彦惣俊吾,坂田泰史
- Organizer
  第25回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Modeling Augmented Sarcomeric Calcium Retention and Altered Calcium Handling Pathway by TNNT2 Δ160E Mutation using Isogenic Human iPS Cell-derived Cardiomyocytes2021
- Author(s)
  Takumi Kondo,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Shota Okuno,Maki Takeda,Yuki Kuramoto,Jong-Kook Lee,Seiji Takashima,Shigeru Miyagawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第25回日本心不全学会学術集会YIA基礎部門優秀賞
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] トロポニンTΔ160E変異を有するアイソジェニックiPS心筋を用いた拡張相肥大型心筋症の病態解明2021
- Author(s)
  近藤匠巳,肥後修一朗,志波幹夫,小濱康明,亀田聡士,田端智香,井上裕之,奥野翔太,武田真季,藏本勇希,李鍾國,高島成二,宮川繁,彦惣俊吾,坂田泰史
- Organizer
  第7回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] 難治性心筋症に対する個別化医療2021
- Author(s)
  肥後修一朗
- Organizer
  第7回日本心筋症研究会シンポジウム4「心筋症のゲノム研究最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Modeling Augmented Sarcomeric Calcium Retention and Altered Calcium Handling Pathway by TNNT2 Δ160E Mutation using Isogenic Human iPS Cell-derived Cardiomyocytes2021
- Author(s)
  Takumi Kondo,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Shota Okuno,Maki Takeda,Yuki Kuramoto,Jong-Kook Lee,Seiji Takashima,Shigeru Miyagawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第25回日本心不全学会学術集会YIA基礎部門優秀賞
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] 難治性心筋症に対する個別化医療2021
- Author(s)
  肥後修一朗
- Organizer
  第7回日本心筋症研究会シンポジウム4「心筋症のゲノム研究最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Strategies to Promote Homology-directed Repair in Post-mitotic Cardiomyocytes2021
- Author(s)
  Shuichiro Higo,Yasushi Sakata
- Organizer
  ESC CONGRESS 2021 symposium CRISPR/Cas9 gene editing for heart disease: ready for prime time?
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] 悪性心室性頻拍と重症心不全を特徴とする日本におけるホスホランバン p.Arg14del心筋症の臨床像2021
- Author(s)
  田端智香,藏本勇希,大谷朋仁,宮脇大,宮下洋平,世良英子,木岡秀隆,肥後修一朗,朝野仁裕,彦惣俊吾,坂田泰史
- Organizer
  第25回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Modeling Augmented Sarcomeric Calcium Retention and Altered Calcium Handling Pathway by TNNT2 Δ160E Mutation using Isogenic Human iPS Cell-derived Cardiomyocytes2021
- Author(s)
  Takumi Kondo,Shuichiro Higo,Mikio Shiba,Yasuaki Kohama,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Shota Okuno,Maki Takeda,Yuki Kuramoto,Jong-Kook Lee,Seiji Takashima,Shigeru Miyagawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第25回日本心不全学会学術集会YIA基礎部門優秀賞
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] 難治性心筋症に対する個別化医療2021
- Author(s)
  肥後修一朗
- Organizer
  第7回日本心筋症研究会シンポジウム4「心筋症のゲノム研究最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Development of Precision Medicine for Arrhythmogenic Cardiomyopathy using Isogenic Human Disease Model2021
- Author(s)
  Shuichiro Higo,Shungo Hikoso,Yasushi Sakata
- Organizer
  第85日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Development of Precision Medicine for Arrhythmogenic Cardiomyopathy using Isogenic Human Disease Model2021
- Author(s)
  Shuichiro Higo,Shungo Hikoso,Yasushi Sakata
- Organizer
  第85日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Development of Precision Medicine for Arrhythmogenic Cardiomyopathy using Isogenic Human Disease Model2021
- Author(s)
  Shuichiro Higo,Shungo Hikoso,Yasushi Sakata
- Organizer
  第85日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] Strategies to Promote Homology-directed Repair in Post-mitotic Cardiomyocytes2021
- Author(s)
  Shuichiro Higo,Yasushi Sakata
- Organizer
  ESC CONGRESS 2021 symposium CRISPR/Cas9 gene editing for heart disease: ready for prime time?
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] トロポニンTΔ160E変異を有するアイソジェニックiPS心筋を用いた拡張相肥大型心筋症の病態解明2021
- Author(s)
  近藤匠巳,肥後修一朗,志波幹夫,小濱康明,亀田聡士,田端智香,井上裕之,奥野翔太,武田真季,藏本勇希,李鍾國,高島成二,宮川繁,彦惣俊吾,坂田泰史
- Organizer
  第7回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 悪性心室性頻拍と重症心不全を特徴とする日本におけるホスホランバン p.Arg14del心筋症の臨床像2021
- Author(s)
  田端智香,藏本勇希,大谷朋仁,宮脇大,宮下洋平,世良英子,木岡秀隆,肥後修一朗,朝野仁裕,彦惣俊吾,坂田泰史
- Organizer
  第25回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Strategies to Promote Homology-directed Repair in Post-mitotic Cardiomyocytes2021
- Author(s)
  Shuichiro Higo,Yasushi Sakata
- Organizer
  ESC CONGRESS 2021 symposium CRISPR/Cas9 gene editing for heart disease: ready for prime time?
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] Phenotypic Recapitulation and Correction of Desmoglein-2-deficient Cardiomyopathy using Human Induced Pluripotent Stem Cellderived Cardiomyocytes2020
- Author(s)
  志波幹夫,肥後修一朗,近藤匠巳,李俊君,劉莉,小濱康明,亀田聡士,田端智香,井上裕之,中村聡希,武田真季,池田善彦,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第68回日本心臓病学会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Adeno-associated Virus-mediated Gene Delivery Promotes S-Phase Entry-independent Homology-directed Repair in Cardiomyocytes2020
- Author(s)
  Yasuaki Kohama,Shuichiro Higo,Mikio Shiba,Takumi Kondo,Satoki Nakamura,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Seiji Takashima,Shigeru Miyagawa,Yoshiki Sawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第24回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] 不整脈源性右室心筋症（ARVC）を迅速に再現するヒトモデル細胞の樹立2020
- Author(s)
  中村聡希,肥後修一朗,志波幹夫,小濱康明,近藤匠巳,亀田聡士,田端智香,井上裕之,山崎悟,武田真季,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] ハイコンテントイメージング・数値計算ソフトウェアを用いた心筋症iPS 分化心筋におけるカルシウム動態解析2020
- Author(s)
  田端智香,肥後修一朗,増村雄喜,志波幹夫,小濱康明,近藤匠巳,亀田聡士,井上裕之,中村聡希,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Generation of Human Disease Model for Personalized Medicine Targeting Intractable Cardiomyopathy2020
- Author(s)
  Shuichiro Higo, Shungo Hikoso, Shigeru Miyagawa, Yoshiki Sawa, Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会 ESC-JCS Young Researchers Session
- Invited
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Adeno-associated Virus-mediated Gene Delivery Promotes S-Phase Entry-independent Homology-directed Repair in Cardiomyocytes2020
- Author(s)
  Yasuaki Kohama,Shuichiro Higo,Mikio Shiba,Takumi Kondo,Satoki Nakamura,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Seiji Takashima,Shigeru Miyagawa,Yoshiki Sawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第24回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] ハイコンテントイメージング・数値計算ソフトウェアを用いた心筋症iPS 分化心筋におけるカルシウム動態解析2020
- Author(s)
  田端智香,肥後修一朗,増村雄喜,志波幹夫,小濱康明,近藤匠巳,亀田聡士,井上裕之,中村聡希,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Phenotypic Recapitulation and Correction of Desmoglein-2-deficient Cardiomyopathy using Human Induced Pluripotent Stem Cellderived Cardiomyocytes2020
- Author(s)
  志波幹夫,肥後修一朗,近藤匠巳,李俊君,劉莉,小濱康明,亀田聡士,田端智香,井上裕之,中村聡希,武田真季,池田善彦,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第68回日本心臓病学会
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Drug discovery for cardiomyopathies using disease-specific iPDCs2020
- Author(s)
  Shuichiro Higo, Shungo Hikoso, Shigeru Miyagawa, Yoshiki Sawa, Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] Adeno-associated Virus-mediated Gene Delivery Promotes S-Phase Entry-independent Homology-directed Repair in Cardiomyocytes2020
- Author(s)
  Yasuaki Kohama,Shuichiro Higo,Mikio Shiba,Takumi Kondo,Satoki Nakamura,Satoshi Kameda,Tomoka Tabata,Hiroyuki Inoue,Seiji Takashima,Shigeru Miyagawa,Yoshiki Sawa,Shungo Hikoso,Yasushi Sakata
- Organizer
  第24回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] Phenotypic Recapitulation and Correction of Desmoglein-2-deficient Cardiomyopathy using Human Induced Pluripotent Stem Cellderived Cardiomyocytes2020
- Author(s)
  志波幹夫,肥後修一朗,近藤匠巳,李俊君,劉莉,小濱康明,亀田聡士,田端智香,井上裕之,中村聡希,武田真季,池田善彦,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第68回日本心臓病学会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] 不整脈源性右室心筋症（ARVC）を迅速に再現するヒトモデル細胞の樹立2020
- Author(s)
  中村聡希,肥後修一朗,志波幹夫,小濱康明,近藤匠巳,亀田聡士,田端智香,井上裕之,山崎悟,武田真季,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Drug discovery for cardiomyopathies using disease-specific iPSCs2020
- Author(s)
  Shuichiro Higo,Shungo Hikoso,Shigeru Miyagawa,Yoshiki Sawa,Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会 Modelling Cardiovascular Disease with Human iPS Cells: Current Status and Future Prospects
- Invited
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Generation of Human Disease Model for Personalized Medicine Targeting Intractable Cardiomyopathy2020
- Author(s)
  Shuichiro Higo, Shungo Hikoso, Shigeru Miyagawa, Yoshiki Sawa, Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] 不整脈源性右室心筋症（ARVC）を迅速に再現するヒトモデル細胞の樹立2020
- Author(s)
  中村聡希,肥後修一朗,志波幹夫,小濱康明,近藤匠巳,亀田聡士,田端智香,井上裕之,山崎悟,武田真季,高島成二,宮川繁,澤芳樹,彦惣俊吾,坂田泰史
- Organizer
  第6回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] Generation of Human Disease Model for Personalized Medicine Targeting Intractable Cardiomyopathy2020
- Author(s)
  Shuichiro Higo, Shungo Hikoso, Shigeru Miyagawa, Yoshiki Sawa, Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会 ESC-JCS Young Researchers Session
- Invited
- Data Source
  KAKENHI-PROJECT-20K21602
[Presentation] Drug discovery for cardiomyopathies using disease-specific iPSCs2020
- Author(s)
  Shuichiro Higo,Shungo Hikoso,Shigeru Miyagawa,Yoshiki Sawa,Yasushi Sakata
- Organizer
  第84回日本循環器学会学術集会 Modelling Cardiovascular Disease with Human iPS Cells: Current Status and Future Prospects
- Invited
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Generation of Human Disease Model for Personalized Medicine Targeting Intractable Cardiomyopathy2019
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shigeru Miyagawa, Shungo Hikoso and Yasushi Sakata
- Organizer
  第36回 ISHR（国際心臓研究学会日本部会）
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Genome Editing Targeting Cardiovascular Disease2019
- Author(s)
  肥後　修一朗
- Organizer
  第83回日本循環器学会学術集会　モーニングレクチャー
- Invited
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] High-content Image Analysis Combined with Genome Editing Clarifies the Role for Pkd1 as a Sarcoplasmic Reticulum Protein that Regulates Calcium Influx in Cardiomyocytes2019
- Author(s)
  Yuki Masumura, Shuichiro Higo, Takamaru Ishizu, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Satoshi Kameda, Hiroyuki Inoue, Tomoka Tabata, Satoki Nakamura, Seiji Takashima, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
- Organizer
  第3回BCVR
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Therapeutic and Diagnostic Application of Genome Editing for Advanced Heart2019
- Author(s)
  Takamaru Ishizu, Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  第3回BCVR
- Invited
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Generation of Human Disease Model for Personalized Medicine Targeting Intractable Cardiomyopathy2019
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shigeru Miyagawa, Shungo Hikoso and Yasushi Sakata
- Organizer
  第36回 ISHR（国際心臓研究学会日本部会）
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Medical Application of Genome Editing for Advanced Heart Failure2019
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  第83回日本循環器学会学術集会　プレナリーセッション
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Genome Editing Targeting Cardiovascular Disease2019
- Author(s)
  肥後　修一朗
- Organizer
  第83回日本循環器学会学術集会　モーニングレクチャー
- Invited
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] High-content Image Analysis Combined with Genome Editing Clarifies the Role for Pkd1 as a Sarcoplasmic Reticulum Protein that Regulates Calcium Influx in Cardiomyocytes2019
- Author(s)
  Yuki Masumura, Shuichiro Higo, Takamaru Ishizu, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Satoshi Kameda, Hiroyuki Inoue, Tomoka Tabata, Satoki Nakamura, Seiji Takashima, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
- Organizer
  第3回BCVR
- Data Source
  KAKENHI-PROJECT-19K08489
[Presentation] Therapeutic and Diagnostic Application of Genome Editing for Advanced Heart2019
- Author(s)
  Takamaru Ishizu, Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  第3回BCVR
- Invited
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Medical Application of Genome Editing for Advanced Heart Failure2019
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  第83回日本循環器学会学術集会　プレナリーセッション
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Development of Homology-directed Repair-mediated Genome Replacement Targeting Pathological Mutation in Cardiomyocytes2018
- Author(s)
  Takamaru Ishizu, Shuichiro Higo, Shungo Hikoso, Yasushi Sakata
- Organizer
  第1回日本循環器学会基礎研究フォーラム　基礎研究助成講演
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Homology-directed Repair-mediated Genome Replacement Targeting Pathological Mutation in Dilated Cardiomyopathy2018
- Author(s)
  Shuichiro Higo, Takamaru Ishizu, Yuki Masumura, Tomoaki Higo Hikoso Shungo, Sakata Yasushi
- Organizer
  第9回武田科学振興財団薬科学シンポジウム医薬応用を目指したゲノム編集
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] ゲノム編集の重症心不全医療応用2018
- Author(s)
  肥後修一朗、増村雄喜、彦惣俊吾、坂田泰史
- Organizer
  第22回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] 高齢期において進行性難治性心不全を呈しPKD1フレームシフト変異が同定された多発性嚢胞腎の1例2018
- Author(s)
  宮崎友希, 肥後修一朗, 諏訪恵信, 中本敬, 世良英子, 溝手勇, 水野裕八, 藤尾慈, 彦惣俊吾, 坂田泰史
- Organizer
  医学生研修医の日本内科学会ことはじめ2018京都
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2018
- Author(s)
  Yuki Masumura, Shuichiro Higo, Shungo Hikoso, Seiji Takashima, Yasushi Sakata
- Organizer
  第2回BCVR
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Rapid Evaluation of Candidate Causal Gene Mutation using High-content Image Analysis Combined with Targeted Gene Disruption2018
- Author(s)
  Yuki Masumura, Suzuka Kunimatsu, Shuichiro Higo, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Masato Shibamoto, Seiji Takashima, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
- Organizer
  AHA scientific sessions 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation2018
- Author(s)
  Yuki Masumura, Shuichiro Higo, Shungo Hikoso, Seiji Takashima, Yasushi Sakata
- Organizer
  第2回BCVR
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] ゲノム編集の重症心不全医療応用2018
- Author(s)
  肥後修一朗、増村雄喜、彦惣俊吾、坂田泰史
- Organizer
  第22回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Genome Editing in Cardiomyopathy2018
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  European Society of Cardiology Congress 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Multiplexed Measurement of Cell-type Specific Calcium Dynamics Using High-content Image Analysis2018
- Author(s)
  Yuki Masumura, Suzuka Kunimatsu, Shuichiro Higo, Takamaru Ishizu, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Tomoaki Higo, Masato Shibamoto, Seiji Takashima, Shungo Hikoso, Yasushi Sakata
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] ハイコンテントイメージ解析及びゲノム編集を用いた心筋症遺伝子変異の病原性の迅速な評価系の構築2018
- Author(s)
  増村雄喜、國松鈴花、肥後修一朗、小濱康明、志波幹夫、近藤匠巳、肥後友彰、柴本将人、高島成二、宮川繁、彦惣俊吾、坂田泰史
- Organizer
  第3回心筋症研究会 YIA
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] 二度の心停止から蘇生されプラコフィリン2(PKP2)ハプロ不全が同定された不整脈源性右室心筋症(ARVC)の一例2018
- Author(s)
  中村聡希, 肥後修一朗, 南口仁, 世良英子, 水野裕八國松鈴花, 志波幹夫, 高島成二, 彦惣俊吾, 坂田泰史
- Organizer
  第221回日本内科学会近畿地方会
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Genome Editing in Cardiomyopathy2018
- Author(s)
  Shuichiro Higo, Yuki Masumura, Shungo Hikoso, Yasushi Sakata
- Organizer
  European Society of Cardiology Congress 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] 二度の心停止から蘇生されプラコフィリン2(PKP2)ハプロ不全が同定された不整脈源性右室心筋症(ARVC)の一例2018
- Author(s)
  中村聡希, 肥後修一朗, 南口仁, 世良英子, 水野裕八國松鈴花, 志波幹夫, 高島成二, 彦惣俊吾, 坂田泰史
- Organizer
  第221回日本内科学会近畿地方会
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Rapid Evaluation of Candidate Causal Gene Mutation using High-content Image Analysis Combined with Targeted Gene Disruption2018
- Author(s)
  Yuki Masumura, Suzuka Kunimatsu, Shuichiro Higo, Yasuaki Kohama, Mikio Shiba, Takumi Kondo, Masato Shibamoto, Seiji Takashima, Shigeru Miyagawa, Shungo Hikoso, Yasushi Sakata
- Organizer
  AHA scientific sessions 2018（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19543
[Presentation] Clinical application of genome editing for advanced heart failure2018
- Author(s)
  肥後修一朗、増村雄喜、彦惣俊吾、坂田泰史
- Organizer
  第22回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08069
[Presentation] Therapeutic Genome Editing Targeting an Upstream Genetic Basis of Advanced Heart Failure2018
- Author(s)
  Shuichiro Higo, Takamaru Ishizu, Yuki Masumura, Tomoaki Higo, Shungo Hikoso, Yasushi Sakata
- Organizer
  第82回日本循環器学会学術集会　プレナリーセッション
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] 拡張型心筋症遺伝子変異に対する相同組換え修復（HDR）を介したゲノム編集治療の開発2017
- Author(s)
  石津宜丸肥後修一朗　増村雄喜　小濱康明　志波幹夫　肥後友彰　柴本将人　中川彰人　森本幸生　高島成二　彦惣俊吾　坂田泰史
- Organizer
  第2回日本ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] 心筋症遺伝子変異に対する相同組換え修復（HDR）を介したゲノム編集治療の開発2017
- Author(s)
  石津宜丸肥後修一朗　志波幹夫　小濱康明　柴本将人　肥後友彰　中川彰人　増村雄喜　森本幸生　彦惣俊吾　坂田泰史
- Organizer
  第3回心筋症研究会 YIA
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Development of Homology-directed Repair-mediated Genome Replacement Targeting Pathological Mutation in Cardiomyocytes2017
- Author(s)
  Shuichiro Higo, Takamaru Ishizu, Yuki Masumura, Tomoaki Higo,Sachio Morimoto, Seiji Takashima, Shungo Hikoso, Yasushi Sakata
- Organizer
  AHA scientific sessions 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Single Cell Imaging Analysis Clarifies Quantitative Kinetics of RNA in Cardiomyocytes2016
- Author(s)
  増村雄喜, 肥後修一朗, 朝野仁裕, 北風政史, 坂田泰史, 高島成二
- Organizer
  第89 回日本生化学学会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Clarification of the novel mechanism of cardiomyocyte hypertrophy via regulation of RNA metabolism2016
- Author(s)
  増村雄喜, 肥後修一朗, 朝野仁裕, 彦惣俊吾, 坂田泰史, 高島成二
- Organizer
  第33 回ISHR2016
- Place of Presentation
  東京
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-16K09500
[Presentation] Single Cell Imaging Analysis Clarifies RNA Quantity Control Mechanism in Cardiomyocytes2016
- Author(s)
  Yuki Masumura, Shuichiro Higo、Yoshihiro Asano、Hisakazu Kato、Yi Yan、Osamu Tsukamoto、Hidetaka Kioka、Takaharu Hayashi、Yasunori Shintani、Satoru Yamazaki、Tetsuo Minamino、Masafumi Kitakaze、Issei Komuro、Seiji Takashima、Yasushi Sakata.
- Organizer
  第80回日本循環器学会学術集会　Young Investigator's Award Finalists Lectures (Basic Research)
- Place of Presentation
  宮城県仙台市
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26860558
[Presentation] Molecular Discovery Research using TransOmics in Cardiovascular Pathophysiology.2015
- Author(s)
  Shuichiro Higo, Yuki Masumura, Yoshihiro Asano, Issei Komuro, Masafumi Kitakaze, Yasushi Sakata and Seiji Takashima.
- Organizer
  第79回日本循環器学会学術集会　シンポジウム
- Place of Presentation
  大阪府大阪市
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26860558
[Presentation] 定量的エピゲノム解析を用いた心臓線維芽細胞における細胞周期制御因子の同定2014
- Author(s)
  肥後修一朗、朝野仁裕、増村雄喜、坂田泰史、澤芳樹、北風政史、小室一成、高島成二
- Organizer
  第51回日本臨床分子医学会
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] 定量的エピゲノム解析を用いた心臓線維芽細胞における細胞周期制御因子の同定2014
- Author(s)
  肥後　修一朗
- Organizer
  第51回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] 定量的エピゲノム解析を用いた心臓線維芽細胞における細胞周期制御因子の同定2014
- Author(s)
  肥後　修一朗、朝野　仁裕、増村　雄喜、坂田　泰史、澤　　芳樹、北風　政史、小室　一成、高島　成二
- Organizer
  第51回日本臨床分子医学会
- Place of Presentation
  東京
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26860558
[Presentation] Comprehensive quantitative epigenome mapping reveals the differential induction of histone H3 lysine 4 trimethylation marks in pressure-overloaded murine hearts2013
- Author(s)
  肥後　修一朗
- Organizer
  AHA scientific sessions 2012
- Place of Presentation
  Losangels, USA
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Quantitative Epigenome Mapping Reveals the Differentially Induced Histone H3 Lysine 4 Trimethylation Marks in Pressure-overloaded Failing Hearts2012
- Author(s)
  肥後　修一朗
- Organizer
  Molecular Cardiovascular Conference II
- Place of Presentation
  北海道赤井川村キロロ
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Quantitative ChIP-Sequence Analysis Reveals the Differentially Altered Active Epigenomic States in Murine Pressure-Overloaded Failing Hearts2012
- Author(s)
  Higo Shuichiro, Asano Yoshihiro, Takashima Seiji, Kitakaze Masafumi, Komuro Issei
- Organizer
  The 29th Annual Meeting of the International Society for Heart Research Japanese Section
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] Quantitative ChIP-sequence Analysis Reveals the Differentially Altered Active Epigenomic States in Murine Pressure-overloaded Failing Hearts2012
- Author(s)
  肥後　修一朗
- Organizer
  第29回ISHR日本部会総会
- Place of Presentation
  九州大学　福岡
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Quantitative ChIP-sequence Analysis Reveals the Differentially Altered Active Epigenomic States in Murine Pressure-overloaded Failing Hearts.2012
- Author(s)
  Shuichiro Higo, Yoshihiro Asano, Seiji Takashima, Masafumi Kitakaze, Issei Komuro
- Organizer
  第29回ISHR日本部会総会
- Place of Presentation
  九州大学福岡
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Comprehensive quantitative epigenome mapping reveals the differential induction of histone H3 lysine 4 trimethylation.2012
- Author(s)
  Shuichiro Higo, Yoshihiro Asano, Seiji Takashima, Masafumi Kitakaze, Issei Komuro
- Organizer
  AHA scientific sessions
- Place of Presentation
  Losangels, USA
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Quantitative Epigenome Mapping Reveals the Differentially Induced Histone H3 Lysine 4 Trimethylation Marks in Pressure-overloaded Failing Hearts.2012
- Author(s)
  Shuichiro Higo, Yoshihiro Asano, Seiji Takashima, Issei Komuro
- Organizer
  Molecular CardiovascularConference II
- Place of Presentation
  北海道赤井川村キロロ
- Data Source
  KAKENHI-PROJECT-24790757
[Presentation] Meox1 is a Cell-cycle Oscillator Required for Mitotic Transition and Proliferation in Cardiac Fibroblasts
- Author(s)
  Shuichiro Higo, Yoshihiro Asano, Yuki Masumura, Yasushi Sakata, Masafumi Kitakaze, Seiji Takashima
- Organizer
  BASIC CARDIOVASCULAR SCIENCES 2014 SCIENTIFIC SESSIONS
- Place of Presentation
  Las Vegas, Nevada, USA
- Year and Date
  2014-07-14 – 2014-07-17
- Data Source
  KAKENHI-PROJECT-26860558
[Presentation] Comprehensive quantitative epigenome mapping reveals the differential induction of histone H3 lysine 4 trimethylation marks in pressure-overloaded murine hearts
- Author(s)
  Shuichiro Higo,Yoshihiro Asano, Seiji Takashima, Masafumi Kitakaze, Issei Komuro
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles、USA
- Data Source
  KAKENHI-PROJECT-24591097

1. ASANO Yoshihiro (60527670)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
2. TSUKAMOTO Osamau (80589151)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
3. Sakata Yasushi (00397671)

# of Collaborated Projects: 6 results

# of Collaborated Products: 40 results
4. Hikoso Shungo (30423164)

# of Collaborated Projects: 5 results

# of Collaborated Products: 61 results
5. MINAMINO TETSUO (30379234)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SANADA Shoji (70593797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TAKASHIMA Seiji (90379272)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
8. 大谷朋仁 (30623897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. HAO Hiroyuki (40393243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATO Hisakazu (30589312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OGITA Hisakazu (50379236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHINTANI Yasunori (20712243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 辻川和丈 (10207376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 木岡秀隆 (70642099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田端智香 (30973094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Yan Yi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ASAKURA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. MIN Kyung-Duk

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. TO Seikon

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. NAKANO Astushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. ITO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 本田知之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 北風政史

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
24. 山崎悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
25. 浅沼博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
26. 野地博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 森本幸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中山博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 泉知里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 畠山金太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 浅井知浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 小倉尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Higo Shuichiro 肥後 修一朗

HIGO Schuichiro 肥後 修一朗

KATO Hisakazu 加藤 久和

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Development of interventional therapy for desmosomal cardiomyopathyPrincipal Investigator

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Therapeutic development targeting molecular basis of dilated-phase hypertrophic cardiomyopathyPrincipal Investigator

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Therapeutic Application of Genome Editing for Advanced Heart FailurePrincipal Investigator

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Molecular discovery research targeting cardiac remodeling using multi-directional transcriptional profiling and therapeutic applicationPrincipal Investigator

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Higo Shuichiro 肥後修一朗

HIGO Schuichiro 肥後修一朗

KATO Hisakazu 加藤久和

[Book] 心不全のサイエンス　ゲノム編集の難治性心筋症医療応用2019