ASANO YOSHIHIRO 朝野仁裕

… Alternative Names

ASANO Yoshihiro 朝野仁裕

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Researcher Number	60527670
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立循環器病研究センター, 病院, 部長 2025: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, バイオバンク長 2025: 大阪大学, 大学院医学系研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help	2023 – 2025: 国立研究開発法人国立循環器病研究センター, 病院, 部長 2022 – 2024: 大阪大学, 大学院医学系研究科, 特任准教授(常勤) 2021: 大阪大学, 医学系研究科, 特任准教授(常勤) 2016 – 2020: 大阪大学, 医学系研究科, 講師 2016 – 2017: 大阪大学, 大学院医学系研究科, 講師 … More 2014 – 2015: 大阪大学, 大学院医学系研究科, 助教 2012 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教 2014: 大阪大学, 医学系研究科 2011: 大阪大学, 大学院・医学系研究科, 助教 2010 – 2011: 大阪大学, 医学系研究科, 助教 2009 – 2010: Osaka University, 医学系研究科, 寄附講座助教 Less
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Circulatory organs internal medicine / Medium-sized Section 53:Organ-based internal medicine and related fields / Cardiovascular medicine Except Principal Investigator Cardiovascular medicine / Basic Section 53020:Cardiology-related / Circulatory organs internal medicine / Medium-sized Section 28:Nano/micro science and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medical sociology
Keywords	Principal Investigator 心筋症 / 分子循環器病学 / エピゲノム / 創薬開発 / 臨床循環器 / 難治性心不全 / 細胞核クロマチン / 創薬標的 / 病態解明 / ゲノム医療 … More / 病態機序 / リスク因子 / 病原性バリアント / 全ゲノム解析 / 新規治療法開発 / 新規治療薬開発 / 創薬 / オミックス / ゲノム / 創薬治療法開発 / オミックス研究 / ゲノムデータベース構築 / 選択的阻害薬 / チャネル遺伝子 / ゲノム解析 / 洞不全症候群 / 徐脈性不整脈 / 分子循環器学 / 希少難病 / ピストン修飾 / ヒストン修飾 / 胎児性遺伝子 / クロマチン免疫沈降法 / ヘテロクロマチン / 分子心臓病態学 … More Except Principal Investigator 心不全 / 循環器・高血圧 / 人工臓器学 / 再生医工学 / ナノマイクロバイオシステム / BioMEMS / ナノマイクロ加工 / 特発性冠動脈解離 / ゲノム編集 / iPS細胞 / ディープフェノタイピング / 疾患iPS細胞 / 心筋症 / 心血管イベント / 疾患特異的iPS細胞 / 心血管イベントリスク / 登録観察研究 / 治療薬探索 / iPS由来心筋細胞 / 遺伝性心血管疾患 / 不整脈 / 肥大型心筋症 / 次世代シークエンサー / 遺伝学的検査 / 拡張型心筋症 / ゲノム / HLA / 心臓サルコイドーシス / サルコイドーシス / cardiac MLCK / キナーゼ活性化機構 / ｃMLCK / サルコメア / ミオシン調節軽鎖キナーゼ / 医療・福祉 / 肺高血圧症 / 遺伝子 / 肺高血圧 / 患者との協働 / 患者とのコミュニケーション / 患者参加型研究 / ダイナミック・コンセント / 研究ガバナンス / 医学研究 / 発現制御 / メカニカルストレス / 転写因子 / BNP / 創薬 / シグナル伝達 / エンハンサー / ナトリウム利尿ホルモン / モデル動物 / 利尿ホルモン / 細胞遊走 / Pdlim5 / AMPキナーゼ / ｃｅｌｌ　ｍｉｇｒａｔｉｏｎ / ＡＭＰＫ / cell migration / PDLIM5 / AMPK / アポトーシス / 心筋肥大 / NF-kB / MAPキナーゼ / ST2受容体 / IL-33 / G蛋白共役性受容体 / 心筋細胞 / 心筋リモデリング / G蛋白共役受容体 / 内因性免疫 / 心筋保護 / 自然免疫 / 慢性心不全 / ジスルフィド結合 / 低酸素 / 腹部大動脈瘤 / 小胞体ストレス / 細胞・組織 / 生体分子 / 組織・細胞 Less

Elucidation of the pathophysiology of cardiomyopathy and exploration of new drug targets for realization of genomic medicinePrincipal Investigator
- Principal Investigator
  
  朝野仁裕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
特発性冠動脈解離の原因遺伝子ならびに再発機序解明を目指す臨床研究
- Principal Investigator
  
  片岡有
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
全ゲノム解析基盤による機能・情報統合解析と新規心筋症遺伝子の同定および機序解明Principal Investigator
- Principal Investigator
  
  朝野仁裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Fabrication of Stroke-on-a-Chip using microfluidic devices and validation using patient-derived tissue
- Principal Investigator
  
  横川隆司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  Kyoto University
Development of clinical practice for rare intractable cardiomyopathy using deep phenotyping combined with iPS cell technology
- Principal Investigator
  
  Yasushi Sakata
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Research in molecular and epidemiological cohort study of hereditary cardiovascular diseases
- Principal Investigator
  
  Fujino Noboru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kanazawa University
Identification of Novel Molecular Targets and Drug Development by Genomic and Multilayer-Omics Analysis of Hereditary CardiomyopathiesPrincipal Investigator
- Principal Investigator
  
  Asano Yoshihiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Evaluation for genetic predisposition and clinical pathological stratification in cardiac sarcoidosis
- Principal Investigator
  
  Minamiguchi Hitoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Osaka University
Elucidation of the pathological mechanism of KACh channelopathy and development of novel heart rate modulating drugPrincipal Investigator
- Principal Investigator
  
  Asano Yoshihiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Osaka University
Genetic analysis of familial pulmonary hypertension with the next generation DNA sequencer
- Principal Investigator
  
  Kubota Kayoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kagoshima University
Analysis of the regulatory mechanism of the activity of cardiac specific myosin light chain kinase
- Principal Investigator
  
  Tsukamoto Osamu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Elucidation of the irreversible mechanism of severe heart failure using biological monitoring murine heart failure modelPrincipal Investigator
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Elucidation of the regulatory mechanism of natriuretic hormone expression for oral heart failure drug development
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Development of medical research governance for 21st century by continuous communication with patients
- Principal Investigator
  
  KATO Kazuto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical sociology
- Research Institution
  Osaka University
anti-atherosclerotic and anti-cancer effects of AMPK activation
- Principal Investigator
  
  Tsukamoto Osamu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Development of simple and noninvasive method to assess the severity of heart failure
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Exploration for Aggravating Process of Heart Failure Induced by Specific Interaction with G-protein-coupled Receptor and Toll-like Receptor
- Principal Investigator
  
  Sanada Shoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Role of ER oxidoreductin-1 in cardiovascular remodeling
- Principal Investigator
  
  MINAMINO TETSUO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
A New Diagnostics Method for Refractory Heart FailurePrincipal Investigator
- Principal Investigator
  
  ASANO YOSHIHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
A Study for Epigenetic Regulation to Maintain Cardiac HomeostasisPrincipal Investigator
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Identification and Functional Analysis of Cardiac Specific Singling Molecules and Therapeutic Applications for Cardiovascular Disease
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

[Book] 月刊心臓（公益財団法人日本心臓財団）HEART's Selection　拡張型心筋症の精密医療　5．拡張型心筋症をゲノムで層別化する2021
- Author(s)
  朝野仁裕
- Publisher
  日本医学出版
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] ゲノム・オミックス解析2021
- Author(s)
  朝野仁裕
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 月刊心臓　HEART's Selection　拡張型心筋症の精密医療　拡張型心筋症をゲノムで層別化する2021
- Author(s)
  朝野仁裕
- Publisher
  日本心臓財団・日本循環器学会（日本医学出版）
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 循環器内科　核膜蛋白の変異によってひき起こされる不整脈原性心筋症の新たな分子機序2021
- Author(s)
  四宮春輝, 朝野仁裕
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 新心臓病学　第7章心筋疾患・心膜疾患　不整脈原性右室心筋症2020
- Author(s)
  朝野仁裕
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] CARDIAC PRACTICE　循環器疾患のPrecision Medicine　不整脈Precision Medicineへ向けた試み2020
- Author(s)
  朝野仁裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] CARDIAC PRACTICE　循環器疾患のPrecision Medicine　不整脈Precision Medicineへ向けた試み2020
- Author(s)
  朝野仁裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18K19547
[Book] 新心臓病学　第7章心筋疾患・心膜疾患　不整脈原性右室心筋症2020
- Author(s)
  朝野仁裕
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18K19547
[Book] CARDIAC PRACTICE　循環器疾患のPrecision Medicine　トピック不整脈Precision Medicineへ向けた試み2020
- Author(s)
  朝野仁裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 月刊心臓　HEART's Selection　心臓病に挑むゲノム医療2019
- Author(s)
  朝野仁裕
- Publisher
  日本心臓財団・日本循環器学会（日本医学出版）
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 月刊心臓　心不全層別化に向けた疾患ゲノム解析2019
- Author(s)
  朝野仁裕
- Publisher
  日本心臓財団・日本循環器学会（日本医学出版）
- Data Source
  KAKENHI-PROJECT-18K19547
[Book] 医学のあゆみ　遺伝性心血管疾患のすべて　遺伝性徐脈性不整脈におけるゲノム医療へのアプローチ2019
- Author(s)
  朝野仁裕
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18K19547
[Book] 医学のあゆみ　遺伝性心血管疾患のすべて　遺伝性徐脈性不整脈におけるゲノム医療へのアプローチ2019
- Author(s)
  朝野仁裕
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 月刊心臓　HEART's Selection　心臓病に挑むゲノム医療2019
- Author(s)
  朝野仁裕
- Publisher
  日本心臓財団・日本循環器学会（日本医学出版）
- Data Source
  KAKENHI-PROJECT-18K19547
[Book] 月刊心臓　心不全層別化に向けた疾患ゲノム解析2019
- Author(s)
  朝野仁裕
- Publisher
  日本心臓財団・日本循環器学会（日本医学出版）
- Data Source
  KAKENHI-PROJECT-19H03652
[Book] 「重症心不全の患者さんが来ました」第１０章：「遺伝子」2016
- Author(s)
  朝野仁裕
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09139
[Book] 「ここが知りたい、強心薬のさじ加減」急性心不全：４章：「強心薬の効果が十分でない時の対応」2016
- Author(s)
  朝野仁裕
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09139
[Book] 循環器専門医2015
- Author(s)
  朝野仁裕
- Publisher
  南光堂
- Data Source
  KAKENHI-PROJECT-24591097
[Book] 最新医学　別冊　診断と治療のABC　「心不全」　第２章　病態・病態生理、心筋症の原因遺伝子2015
- Author(s)
  朝野仁裕
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15K09139
[Book] 循環器内科2015
- Author(s)
  朝野仁裕
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24591097
[Book] 医学のあゆみ2013
- Author(s)
  朝野仁裕、小室一成.
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24591097
[Book] メディカルサイエンス病態生化学／臨床化学検査学II 病態の生化学－人体の正常と異常 II-2 臓器機能の生化学 II-2-3 心・循環器機能2013
- Author(s)
  朝野仁裕、小室一成
- Publisher
  近代出版
- Data Source
  KAKENHI-PROJECT-24591097
[Book] 週刊『医学のあゆみ』第一土曜日特集特集「エクソーム解析―成果と将来」「全エクソーム解析による難治性循環器疾患の原因遺伝子の同定」2013
- Author(s)
  朝野仁裕、小室一成
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-24591097
[Book] 心不全の原因・病態に迫る検査「遺伝子診断はどのような症例に行うべきか?」変貌する心不全診療2012
- Author(s)
  朝野仁裕
- Publisher
  南光堂
- Data Source
  KAKENHI-PROJECT-21689022
[Book] 診断と治療　特集　心不全最近の話題　心不全の原因診断の進歩2012
- Author(s)
  朝野仁裕、小室一成
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24591097
[Book] 心不全の原因診断の進歩、心不全2012
- Author(s)
  朝野仁裕、小室一成
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-21689022
[Book] 拡張型心筋症に関する新しい解析方法、CARDIAC PRACTICE2011
- Author(s)
  朝野仁裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21689022
[Book] 医学の歩み心不全-研究と臨床の最前線 1月第5曜特集号2010
- Author(s)
  朝野仁裕、小室一成
- Total Pages
  7
- Publisher
  医歯薬出版社
- Data Source
  KAKENHI-PROJECT-21689022
[Book] 心不全におけるクロマチンリモデリングの役割、Annual Review循環器2010
- Author(s)
  朝野仁裕
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21689022
[Book] 最新・心不全Update-研究と臨床の最前線、心不全の先端的研究トピックス、心不全のジェネティクスとエピジェネティクス、医学のあゆみ2010
- Author(s)
  朝野仁裕、小室一成
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21689022
[Book] Annual Review 2010循環器2010
- Author(s)
  朝野仁裕
- Total Pages
  7
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-21689022
[Book] Altered epigenetic memory with chromatin disruption in the end-stage failing heart.分子心血管病2009
- Author(s)
  朝野仁裕
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] End-stage Hypertrophic Cardiomyopathy with Advanced Heart Failure in Patients Carrying <i>MYH7</i> R453 Variants: A Case Series2023
- Author(s)
  Naito Susumu、Higo Shuichiro、Kameda Satoshi、Ogawa Shou、Tabata Tomoka、Akazawa Yasuhiro、Nakamura Daisuke、Nakamoto Kei、Sera Fusako、Kuramoto Yuki、Aasano Yoshihiro、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 21 Pages: 3167-3173
- DOI
  10.2169/internalmedicine.1497-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02915
[Journal Article] Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin2023
- Author(s)
  Hitsumoto T, Tsukamoto O, Matsuoka K, Li J, Liu L, Kuramoto Y, Higo S, Ogawa S, Fujino N, Yoshida S, Kioka H, Kato H, Hakui H, Saito Y, Okamoto C, Inoue H, Hyejin J, Ueda K, Segawa T, Nishimura S, Asano Y, Asanuma H, Tani A, Imamura R, Komagawa S, Kanai T, Takamura M, Sakata Y, Kitakaze M, Haruta JI, Takashima S.
- Journal Title
  
  Circulation
  
  Volume: - Issue: 25 Pages: 1902-1918
- DOI
  10.1161/circulationaha.122.062885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-23KJ1480, KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20H03927, KAKENHI-PROJECT-23K24327
[Journal Article] Genetic assessment using whole-exome sequencing for a young hypertriglyceridemic patient with repeated acute pancreatitis2022
- Author(s)
  Fujita Shingo、Nishizawa Hitoshi、Miyashita Yohei、Imada Tasuku、Yamaguchi Takashi、Murano Takeyoshi、Bujo Hideaki、Asano Yoshihiro、Kozawa Junji、Maeda Norikazu、Shimomura Iichiro
- Journal Title
  
  Endocr J
  
  Volume: 69 Issue: 9 Pages: 1101-1108
- DOI
  10.1507/endocrj.EJ22-0024
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-23K24328
[Journal Article] Novel BCL11B truncation variant in a patient with developmental delay, distinctive features, epilepsy, and early craniosynostosis2022
- Author(s)
  Eto K, Machida O, Yanagishita T, Yamamoto Shimojima K, Chiba K, Aihara Y, Nagata M, Isihara Y, Miyashita Y, Asano Y, Nagata S, Toshiyuki Yamamoto T
- Journal Title
  
  Human Genome Variation
  
  Volume: 9 Issue: 1 Pages: 43-43
- DOI
  10.1038/s41439-022-00220-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07873, KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-23K24328
[Journal Article] Phospholamban p.Arg14del Cardiomyopathy: A Japanese Case Series2022
- Author(s)
  Tabata Tomoka、Kuramoto Yuki、Ohtani Tomohito、Miyawaki Hiroshi、Miyashita Yohei、Sera Fusako、Kioka Hidetaka、Higo Shuichiro、Asano Yoshihiro、Hikoso Shungo、Sakata Yasushi
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 13 Pages: 1987-1993
- DOI
  10.2169/internalmedicine.8594-21
- NAID
  130008130223
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08489, KAKENHI-PROJECT-20K21602, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-23K24328, KAKENHI-PROJECT-19H03652
[Journal Article] A novel nonsense variant in ARID1B causing simultaneous RNA decay and exon skipping is associated with Coffin-Siris syndrome2022
- Author(s)
  Sofronova Viktoriia、Fukushima Yu、Masuno Mitsuo、Naka Mami、Nagata Miho、Ishihara Yasuki、Miyashita Yohei、Asano Yoshihiro、Moriwaki Takahito、Iwata Rina、Terawaki Seigo、Yamanouchi Yasuko、Otomo Takanobu
- Journal Title
  
  Human Genome Variation
  
  Volume: 9 Issue: 1 Pages: 1-6
- DOI
  10.1038/s41439-022-00203-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06857, KAKENHI-PROJECT-20K17055, KAKENHI-PROJECT-23K24328
[Journal Article] Loss-of-function mutations in the co-chaperone protein BAG5 cause dilated cardiomyopathy requiring heart transplantation2022
- Author(s)
  Hakui Hideyuki、Kioka Hidetaka、Miyashita Yohei、Nishimura Shunsuke、Matsuoka Ken、Kato Hisakazu、Tsukamoto Osamu、（3人省略）、Saito Shigeyoshi、Ohta Kunio、Asanuma Hiroshi、Fu Hai Ying、Shinomiya Haruki、Yamada Noriaki、Ohtani Tomohito、Sawa Yoshiki、Kitakaze Masafumi、Takashima Seiji、Sakata Yasushi、Asano Yoshihiro
- Journal Title
  
  Science Translational Medicine
  
  Volume: 14 Issue: 628
- DOI
  10.1126/scitranslmed.abf3274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-19H03652
[Journal Article] A Mild Clinical Phenotype with Myopathic and Hemolytic Forms of Phosphoglycerate Kinase Deficiency (PGK Osaka): A Case Report and Literature Review2022
- Author(s)
  Baba K, Fukuda T, Furuta M, Tada S, Imai A, Asano Y, Sugie H, P Takahashi M, Mochizuki H
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 23 Pages: 3589-3594
- DOI
  10.2169/internalmedicine.9221-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-12-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24328
[Journal Article] Compound heterozygous variants of the NARS2 gene in siblings with developmental delay, epilepsy, and neonatal diabetes syndrome2022
- Author(s)
  Yagasaki Hideaki、Sano Fumikazu、Narusawa Hiromune、Watanabe Daisuke、Kaga Yoshimi、Kobayashi Koji、Asano Yoshihiro、Nagata Miho、Yonei Ayumi、Inukai Takeshi
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: 188 Issue: 8 Pages: 2466-2471
- DOI
  10.1002/ajmg.a.62873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08154, KAKENHI-PROJECT-23K24328
[Journal Article] Refractory Ventricular Arrhythmias in a Patient With Dilated Cardiomyopathy Caused by a Nonsense Mutation in <i>BAG5</i>2022
- Author(s)
  Hakui Hideyuki、Kioka Hidetaka、Sera Fusako、Nakamoto Kei、Ozu Kentaro、Kuramoto Yuki、Miyashita Yohei、Ohtani Tomohito、Hikoso Shungo、Asano Yoshihiro、Sakata Yasushi
- Journal Title
  
  Circ J
  
  Volume: 86 Issue: 12 Pages: 2043
- DOI
  10.1253/circj.CJ-22-0329
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2022-11-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-22K08155, KAKENHI-PROJECT-22K20919, KAKENHI-PROJECT-23K24328
[Journal Article] Whole-exome Sequencing Analysis of a Japanese Patient With Hyperinsulinemia and Liver Dysfunction2022
- Author(s)
  Fujita Shingo、Horitani Emi、Miyashita Yohei、Fujita Yukari、Fukui Kenji、Kamada Yoshihiro、Mineo Ikuo、Asano Yoshihiro、Iwahashi Hiromi、Kozawa Junji、Shimomura Iichiro
- Journal Title
  
  Journal of the Endocrine Society
  
  Volume: 6 Issue: 3
- DOI
  10.1210/jendso/bvac008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08027, KAKENHI-PROJECT-20K08383, KAKENHI-PROJECT-23K24328, KAKENHI-PROJECT-19H03652
[Journal Article] Arrhythmogenic right ventricular cardiomyopathy complicating hypertrophic cardiomyopathy2022
- Author(s)
  Kagawa Y, Okamoto R, Asano Y, Sakata Y, Dohi K
- Journal Title
  
  Eur Heart J Cardiovasc Imaging
  
  Volume: 23 Issue: 5 Pages: 635-642
- DOI
  10.1093/ehjci/jeac136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24328
[Journal Article] Cardiac Fibroblasts Play Pathogenic Roles in Idiopathic Restrictive Cardiomyopathy2021
- Author(s)
  Tsuru Hirofumi、Ishida Hidekazu、Narita Jun、Ishii Ryo、Suginobe Hidehiro、Ishii Yoichiro、Wang Renjie、Kogaki Shigetoyo、Taira Masaki、Ueno Takayoshi、Miyashita Yohei、Kioka Hidetaka、Asano Yoshihiro、Sawa Yoshiki、Ozono Keiichi
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 5 Pages: 677-686
- DOI
  10.1253/circj.CJ-20-1008
- NAID
  130008028981
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-04-23
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07789, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K17561, KAKENHI-PROJECT-19H03652
[Journal Article] Visualization of Spatial Distribution of Spermatogenesis in Mouse Testes Using Creatine Chemical Exchange Saturation Transfer Imaging2021
- Author(s)
  Takahashi Yusuke、Kioka Hidetaka、Fukuhara Shinichiro、Kuribayashi Sohei、Saito Shigeyoshi、Asano Yoshihiro、Takashima Seiji、Yoshioka Yoshichika、Sakata Yasushi
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 54 Issue: 5 Pages: 1457-1465
- DOI
  10.1002/jmri.27734
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K08172, KAKENHI-PROJECT-21K15776, KAKENHI-PROJECT-19H03652
[Journal Article] A recurrent de novo ZSWIM6 variant in a Japanese patient with severe neurodevelopmental delay and frequent vomiting2021
- Author(s)
  Yanagishita Tomoe、Eto Kaoru、Yamamoto-Shimojima Keiko、Segawa Osamu、Nagata Miho、Ishihara Yasuki、Miyashita Yohei、Asano Yoshihiro、Sakata Yasushi、Nagata Satoru、Yamamoto Toshiyuki
- Journal Title
  
  Human Genome Variation
  
  Volume: 8 Issue: 1
- DOI
  10.1038/s41439-021-00148-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03652
[Journal Article] Aberrant accumulation of TMEM43 accompanied by perturbed transmural gene expression in arrhythmogenic cardiomyopathy2021
- Author(s)
  Shinomiya Haruki、Kato Hisakazu、・・・・・・・・Mashimo Tomoji、・・・・・・・・・・・・・・・・Sakata Yasushi、Asano Yoshihiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 11
- DOI
  10.1096/fj.202100800r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-19H03652
[Journal Article] Recurrent de novo pathogenic variant of WASF1 in a Japanese patient with neurodevelopmental disorder with absent language and variable seizures2021
- Author(s)
  Shimojima Yamamoto Keiko、Yanagishita Tomoe、Yamamoto Hisako、Miyamoto Yusaku、Nagata Miho、Ishihara Yasuki、Miyashita Yohei、Asano Yoshihiro、Sakata Yasushi、Yamamoto Toshiyuki
- Journal Title
  
  Human Genome Variation
  
  Volume: 8 Issue: 1 Pages: 43-43
- DOI
  10.1038/s41439-021-00176-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07873, KAKENHI-PROJECT-18H04078, KAKENHI-PROJECT-19H03652
[Journal Article] ASB2 is a novel E3 ligase of SMAD9 required for cardiogenesis2021
- Author(s)
  Min Kyung-Duk、Asakura Masanori、Shirai Manabu、Yamazaki Satoru、Ito Shin、Fu Hai Ying、Asanuma Hiroshi、Asano Yoshihiro、Minamino Tetsuo、Takashima Seiji、Kitakaze Masafumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 23056-23056
- DOI
  10.1038/s41598-021-02390-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-19H03652
[Journal Article] HECW2-related disorder in four Japanese patients2021
- Author(s)
  Yanagishita T, Hirade T, Shimojima Yamamoto K, Funatsuka M, Miyamoto Y, Maeda M, Yanagi K, Kaname T, Nagata S, Nagata M, Ishihara Y, Miyashita Y, Asano Y, Sakata Y, Kosaki K, Yamamoto T
- Journal Title
  
  Am Med Genet A
  
  Volume: 185 Issue: 10 Pages: 2895-2902
- DOI
  10.1002/ajmg.a.62363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09916, KAKENHI-PROJECT-21K07873, KAKENHI-PROJECT-19H03652
[Journal Article] Cardio- and reno-protective effects of dipeptidyl peptidase III in diabetic mice2021
- Author(s)
  Komeno M, Pang X, Shimizu A, Molla MR, Yasuda-Yamahara M, Kume S, Rahman NIA, Soh JEC, Nguyen LKC, Ahmat Amin MKB, Kokami N, Sato A, Asano Y, Maegawa H, Ogita H
- Journal Title
  
  J Biol Chem
  
  Volume: 296 Pages: 100761-100761
- DOI
  10.1016/j.jbc.2021.100761
- NAID
  120007045058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08489, KAKENHI-PROJECT-21K09419, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H03652
[Journal Article] The CR9 element is a novel mechanical load‐responsive enhancer that regulates natriuretic peptide genes expression2021
- Author(s)
  Miyashita Y, Tsukamoto O, Matsuoka K, Kamikubo K, Kuramoto Y, Fu HY, Tsubota T, Hasuike H, Takayama T, Ito H, Hitsumoto T, Okamoto C, Kioka H, Oya R, Shinomiya H, Hakui H, Shintani Y, Kato H, Kitakaze M, Sakata Y, Asano Y, Takashima S
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 4
- DOI
  10.1096/fj.202002111rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-20K17151, KAKENHI-PROJECT-19H03652
[Journal Article] Visualization of Spatial Distribution of Spermatogenesis in Mouse Testes Using Creatine Chemical Exchange Saturation Transfer (CrCEST) Imaging.2021
- Author(s)
  Takahashi Y, Kioka H, Saito S, Fukuhara S, Asano Y, Takashima S, Yoshioka Y, Sakata Y.
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: in-press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03652
[Journal Article] Accurate Estimation of the Duration of Testicular Ischemia Using Creatine Chemical Exchange Saturation Transfer ( CrCEST ) Imaging2020
- Author(s)
  Takahashi Yusuke、Kioka Hidetaka、Saito Shigeyoshi、Fukuhara Shinichiro、Asano Yoshihiro、Takashima Seiji、Yoshioka Yoshichika、Sakata Yasushi
- Journal Title
  
  Journal of Magnetic Resonance Imaging
  
  Volume: 53 Issue: 5 Pages: 1559-1567
- DOI
  10.1002/jmri.27456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-19H03652
[Journal Article] Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases.2020
- Author(s)
  Hayashi K, et al.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 0 Issue: 13 Pages: 0-0
- DOI
  10.1093/cvr/cvaa010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-17K15995, KAKENHI-PROJECT-19H03652
[Journal Article] In vivo real‐time ATP imaging in zebrafish hearts reveals G0s2 induces ischemic tolerance2020
- Author(s)
  Kioka Hidetaka、Kato Hisakazu、Fujita Takeshi、Asano Yoshihiro、Shintani Yasunori、Yamazaki Satoru、Tsukamoto Osamu、Imamura Hiromi、Kogo Mikihiko、Kitakaze Masafumi、Sakata Yasushi、Takashima Seiji
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 2 Pages: 2041-2054
- DOI
  10.1096/fj.201901686r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] Non-Radioactive In Vitro Cardiac Myosin Light Chain Kinase Assays2020
- Author(s)
  Kamikubo Kenta、Tsukamoto Osamu、Uyama-Saito Yuki、Oya Ryohei、Tsubota Tomoya、Fujino Noboru、Asano Yoshihiro、Kato Hisakazu、Matsuoka Ken、Takashima Seiji
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 160 Issue: 160 Pages: 1-1
- DOI
  10.3791/61168
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-18H04050, KAKENHI-PROJECT-19H03652
[Journal Article] Identification of transmembrane protein 168 mutation in familial Brugada syndrome.2020
- Author(s)
  Shimizu A, Zankov DP, Sato A, Komeno M, Toyoda F, Yamazaki S, Makita T, Noda T, Ikawa M, Asano Y, Miyashita Y, Takashima S, Morita H, Ishikawa T, Makita N, Hitosugi M, Matsuura H, Ohno S, Horie M, Ogita H.
- Journal Title
  
  FASEB Journal
  
  Volume: 34 Issue: 5 Pages: 6399-6417
- DOI
  10.1096/fj.201902991r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08075, KAKENHI-PROJECT-18K19550, KAKENHI-PROJECT-18KK0245, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-17K08536, KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-20K08489, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K15894, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K08033, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-21K08119
[Journal Article] Mutant KCNJ3 and KCNJ5 potassium channels as novel molecular targets in bradyarrhythmias and atrial fibrillation.2019
- Author(s)
  Yamada N, Asano Y, Fujita M, Yamazaki S, Inanobe A, Matsuura N, Kobayashi H, Ohno S, Ebana Y, Tsukamoto O, Ishino S, Takuwa A, Kioka H, Yamashita T, Hashimoto N, Zankov DP, Shimizu A, Asakura M, Asanuma H, Kato H, Nishida Y, Miyashita Y, Shinomiya H, Naiki N, Hayashi K, Makiyama T, Ogita H, et al.
- Journal Title
  
  Circulation
  
  Volume: In press Issue: 18 Pages: 2157-2169
- DOI
  10.1161/circulationaha.118.036761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08627, KAKENHI-PROJECT-17K08657, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-17K09578, KAKENHI-PROJECT-18K07875, KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-17F17418, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-17K07251, KAKENHI-PROJECT-18K08033, KAKENHI-PROJECT-19K08538, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-17K09495, KAKENHI-PROJECT-17H04018, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04074, KAKENHI-PROJECT-18H02803, KAKENHI-PROJECT-18H02808, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-19H03652
[Journal Article] Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese2019
- Author(s)
  Ogawa, Kotaro; Okuno, Tatsusada; Hosomichi, Kazuyoshi; Hosokawa, Akiko; Hirata, Jun; Suzuki, Ken; Sakaue, Saori; Kinoshita, Makoto; Asano, Yoshihiro; Miyamoto, Katsuichi
- Journal Title
  
  Journal of neuroinflammation
  
  Volume: 16 Issue: 1 Pages: 162-162
- DOI
  10.1186/s12974-019-1551-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17962, KAKENHI-PLANNED-15H05911, KAKENHI-PLANNED-16H06502, KAKENHI-PUBLICLY-19H05344, KAKENHI-PROJECT-17K09779, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547
[Journal Article] Higd1a improves respiratory function in the models of mitochondrial disorder2019
- Author(s)
  Nagao Takemasa、Shintani Yasunori、Hayashi Takaharu、Kioka Hidetaka、Kato Hisakazu、Nishida Yuya、Yamazaki Satoru、Tsukamoto Osamu、Yashirogi Shohei、Yazawa Issei、Asano Yoshihiro、Shinzawa‐Itoh Kyoko、Imamura Hiromi、Suzuki Takeo、Suzuki Tsutomu、Goto Yu‐ichi、Takashima Seiji
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 1859-1871
- DOI
  10.1096/fj.201800389r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K22246, KAKENHI-PROJECT-17H03646, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-18H02094, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-18H05272, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] AST-120, an Adsorbent of Uremic Toxins, Improves the Pathophysiology of Heart Failure in Conscious Dogs.2019
- Author(s)
  Asanuma H, Chung H, Ito S, Min KD, Ihara M, Takahama H, Funayama M, Imazu M, Fukuda H, Ogai A, Asano Y, Minamino T, Takashima S, Morita T, Sugimachi M, Asakura M, Kitakaze M.
- Journal Title
  
  Cardiovasc Drugs Ther.
  
  Volume: 33 Issue: 3 Pages: 277-286
- DOI
  10.1007/s10557-019-06875-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08052, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-19H03652
[Journal Article] Impact of cardiac myosin light chain kinase gene mutation on development of dilated cardiomyopathy2019
- Author(s)
  Hodatsu A, Fujino N, Uyama Y, Tsukamoto O, Imai-Okazaki A, Yamazaki S, Seguchi O, Konno T, Hayashi K, Kawashiri MA, Asano Y, Kitakaze M, Takashima S, Yamagishi M
- Journal Title
  
  ESC Heart Fail
  
  Volume: 6 Issue: 2 Pages: 06-415
- DOI
  10.1002/ehf2.12410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09578, KAKENHI-PROJECT-18K08100, KAKENHI-PROJECT-18H04050, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-15H04826, KAKENHI-PROJECT-19K08553, KAKENHI-PROJECT-19K09408, KAKENHI-PROJECT-18K15863, KAKENHI-PROJECT-17K09082, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-19H03652
[Journal Article] A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G0/G1 switch gene 22019
- Author(s)
  Kamikubo Kenta、Kato Hisakazu、Kioka Hidetaka、Yamazaki Satoru、Tsukamoto Osamu、Nishida Yuya、Asano Yoshihiro、Imamura Hiromi、Kawahara Hiroyuki、Shintani Yasunori、Takashima Seiji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 40 Pages: 14562-14573
- DOI
  10.1074/jbc.ra119.008544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08105, KAKENHI-PROJECT-19K08581, KAKENHI-PROJECT-19K09408, KAKENHI-PUBLICLY-19H05293, KAKENHI-PROJECT-17H03654, KAKENHI-PROJECT-17H03657, KAKENHI-PROJECT-17K09577, KAKENHI-PROJECT-19K22386, KAKENHI-PROJECT-19H03652, KAKENHI-PROJECT-18K19547, KAKENHI-PROJECT-17K09578
[Journal Article] Successful treatment of severe combined post- and pre- capillary pulmonary hypertension in a patient with idiopathic restrictive cardiomyopathy.2018
- Author(s)
  S. Ishihara, H. Kioka, T. Ohtani, Y. Asano, O. Yamaguchi, S. Hikoso, K. Toda, Y. Saito, Y. Sawa, K. Yamauchi-Takihara, Y. Sakata
- Journal Title
  
  Pulm Circ
  
  Volume: 8 Issue: 3 Pages: 1-5
- DOI
  10.1177/2045894018770131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01712, KAKENHI-PROJECT-16K09501, KAKENHI-PROJECT-18K19547
[Journal Article] How to Eliminate Uncertainty in Clinical Medicine - Clues from Creation of Mathematical Models Followed by Scientific Data Mining.2018
- Author(s)
  Asano Y.
- Journal Title
  
  EBioMedicine.
  
  Volume: S2352 Pages: 30240-8
- DOI
  10.1016/j.ebiom.2018.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19547
[Journal Article] Anti-HB-EGF Antibody-Mediated Delivery of siRNA to Atherosclerotic Lesions in Mice2018
- Author(s)
  Shota Tsuchida, Takashi Matsuzaki, Masaki Yamato, Keiji Okuda, Hai Ying Fu, Ryo Araki, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Hiroyuki Hao, Seiji Takashima, Masafumi Kitakaze, Yasushi Sakata, Eisuke Mekada, Tetsuo Minamino
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 6 Pages: 1425-1431
- DOI
  10.1536/ihj.17-644
- NAID
  130007522227
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-11-30
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19659, KAKENHI-PROJECT-18K19547
[Journal Article] Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling2018
- Author(s)
  Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I.
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 20114-20119
- DOI
  10.1038/s41598-018-20114-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09129, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-17H04061, KAKENHI-PROJECT-17J00085, KAKENHI-PROJECT-17J05937, KAKENHI-PROJECT-15K21388, KAKENHI-PROJECT-17H06566, KAKENHI-PROJECT-17H01560, KAKENHI-PROJECT-15K09139
[Journal Article] Identification of genetic risk factors of aggressive periodontitis using genomewide association studies in association with those of chronic periodontitis.2018
- Author(s)
  Masumoto R, Kitagaki J, Fujihara C*, Matsumoto M, Miyauchi S, Asano Y, Imai A, Kobayashi K, Nakaya A, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: - Issue: 3 Pages: 12620-12620
- DOI
  10.1111/jre.12620
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17349, KAKENHI-PROJECT-18K19547
[Journal Article] Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats.2017
- Author(s)
  Okuda K, Fu HY, Matsuzaki T, Araki R, Tsuchida S, Thanikachalam PV, Fukuta T, Asai T, Yamato M, Sanada S, Asanuma H, Asano Y, Asakura M, Hanawa H, Hao H, Oku N, Takashima S, Kitakaze M, Sakata Y, Minamino T.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 8 Pages: e0160944-e0160944
- DOI
  10.1371/journal.pone.0160944
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-15K12542
[Journal Article] Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells2017
- Author(s)
  S Miyauchi, J Kitagaki, R Masumoto, A Imai, K Kobayashi, A Nakaya, S Kawai, C Fujihara, Y Asano, M Yamashita, M Yanagita, S Yamada, M Kitamura, S. Murakami
- Journal Title
  
  J Dent Res
  
  Volume: 96 Issue: 3 Pages: 339-46
- DOI
  10.1177/0022034516677938
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-15K11385, KAKENHI-PROJECT-16K11828, KAKENHI-PROJECT-15K09139
[Journal Article] Novel Synthesized Radical-Containing Nanoparticles Limit Infarct Size Following Ischemia and Reperfusion in Canine Hearts.2017
- Author(s)
  Asanuma H, Sanada S, Yoshitomi T, Sasaki H, Takahama H, Ihara M, Takahama H, Shinozaki Y, Mori H, Asakura M, Nakano A, Sugimachi M, Asano Y, Minamino T, Takashima S, Nagasaki Y, Kitakaze M.
- Journal Title
  
  Cardiovasc Drugs Ther.
  
  Volume: 31 Issue: 5-6 Pages: 501-510
- DOI
  10.1007/s10557-017-6758-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K16398, KAKENHI-PROJECT-25220203, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-16K15628, KAKENHI-PROJECT-15K09139
[Journal Article] Heat Failure Phenotypes Induced by Knockdown of DAPIT in Zebrafish: A New Insight into Mechanism of Dilated Cardiomyopathy.2017
- Author(s)
  Nagata Y, Yamagishi M, Konno T, Nakanishi C, Asano Y, Ito S, Nakajima Y, Seguchi O, Fujino N, Kawashiri MA, Takashima S, Kitakaze M, Hayashi K.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 17417-17417
- DOI
  10.1038/s41598-017-17572-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-17K15995, KAKENHI-PROJECT-15KK0302, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15K09134
[Journal Article] Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms2017
- Author(s)
  Kondo H, Maksimova N, Otomo T*,Kato H, Imai A, Asano Y, Kobayashi K, Nojima S, Nakaya A, Hamada Y, Irahara K, Gurinova E, Sukhomyasova A, Nogovicina A, Savvina M, Yoshimori T, Ozono K Sakai N*
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 26 Pages: 173-183
- DOI
  10.1093/hmg/ddw377
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25111002, KAKENHI-PROJECT-15H05673, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15K08423, KAKENHI-PROJECT-16K19404, KAKENHI-PROJECT-15K09139
[Journal Article] A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population2016
- Author(s)
  Kitagaki J, Miyauchi S, Asano Y, Imai A, Kawai S, Michikami I, Yamashita M, Yamada S, Kitamura M, Murakami S
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0160765-e0160765
- DOI
  10.1371/journal.pone.0160765
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02579, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-15K11385
[Journal Article] Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy.2016
- Author(s)
  Ito S, Asakura M, Liao Y, Min KD, Takahashi A, Shindo K, Yamazaki S, Tsukamoto O, Asanuma H, Mogi M, Horiuchi M, Asano Y, Sanada S, Minamino T, Takashima S, Mochizuki N, Kitakaze M.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5 Issue: 7
- DOI
  10.1161/jaha.116.003521
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K09111
[Journal Article] A Development of Nucleic Chromatin Measurements as a New Prognostic Marker for Severe Chronic Heart Failure.2016
- Author(s)
  Kanzaki M, Asano Y, Ishibashi-Ueda H, Oiki E, Nishida T, Asanuma H, Kato H, Oka T, Ohtani T, Tsukamoto O, Higo S, Kioka H, Matsuoka K, Sawa Y, Komuro I, Kitakaze M, Takashima S, Sakata Y.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 2 Pages: e0148209-e0148209
- DOI
  10.1371/journal.pone.0148209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K09139
[Journal Article] Histone Deacetylase Inhibitor Phenylbutyrate Exaggerates Heart Failure in Pressure Overloaded Mice independently of HDAC inhibition.2016
- Author(s)
  Ma J, Luo T, Zeng Z, Fu H, Asano Y, Liao Y, Minamino T, Kitakaze M.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34036-34036
- DOI
  10.1038/srep34036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-15K09139
[Journal Article] Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA.2016
- Author(s)
  Masumura Y, Higo S, Asano Y, Kato H, Yan Y, Ishino S, Tsukamoto O, Kioka H, Hayashi T, Shintani Y, Yamazaki S, Minamino T, Kitakaze M, Komuro I, Takashima S, Sakata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 28592-28592
- DOI
  10.1038/srep28592
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15K08271, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-16K09501
[Journal Article] Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5.2015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 6137-6137
- DOI
  10.1038/ncomms7137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-25461119
[Journal Article] Higdla is a oositive regulaator of cytochrome c oxidase2015
- Author(s)
  T. Hayashi, Y. Asano, Y. Shintani, H. Aoyama, H. Kioka, O. Tsukamoto, M. Hikita, K. Shinzawa-Itoh, K. Takajuji, S. Higo, H. Kato, S. Yamazaki, K. Matsuoka, A. Nakano, H. Asanuma, M. Asakura, T. Minamino, Y. Goto, T. Ogura, M. Kitakaze, I. Komuro, Y. Sakata, T. Tsukihara, S. Yoshikawa, S. Takashima
- Journal Title
  
  Proc. Nat. Acad. Sci. U.S.A.
  
  Volume: 112 Issue: 5 Pages: 1553-1558
- DOI
  10.1073/pnas.1419767112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PUBLICLY-25109540, KAKENHI-PROJECT-25860599, KAKENHI-PUBLICLY-26104532, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26670402, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-25461119
[Journal Article] Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5.2015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S..
- Journal Title
  
  Nat Commun.
  
  Volume: 30 Pages: 6137-6150
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670402
[Journal Article] Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart.2014
- Author(s)
  Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S.
- Journal Title
  
  FASEB J.
  
  Volume: 28(4) Issue: 4 Pages: 1870-9
- DOI
  10.1096/fj.13-245522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25118709, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26860559
[Journal Article] Usefulness of transient elastography for noninvasive and reliable estimation of right-sided filling pressure in heart failure.2014
- Author(s)
  Taniguchi T, Sakata Y, Ohtani T, Mizote I, Takeda Y, Asano Y, Masuda M, Minamiguchi H, Kanzaki M, Ichibori Y, Nishi H, Toda K, Sawa Y, Komuro I.
- Journal Title
  
  Am J Cardiol.
  
  Volume: 113 Issue: 3 Pages: 552-8
- DOI
  10.1016/j.amjcard.2013.10.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591097
[Journal Article] Carperitide induces coronary vasodilation and limits infarct size in canine ischemic hearts: Role of NO.2014
- Author(s)
  Asanuma H, Sanada S, Asakura M, Asano Y, Kim J, Shinozaki Y, Mori H, Minamino T, Takashima S,Kitakaze M.
- Journal Title
  
  Hypertens Res.
  
  Volume: 37(8) Issue: 8 Pages: 716-23
- DOI
  10.1038/hr.2014.70
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-26461134
[Journal Article] Comprehensive metagenomic approach for detecting causative microorganisms in culture-negative infective endocarditis.2014
- Author(s)
  Imai A, Gotoh K, Asano Y* (corresponding author), Yamada N, Motooka D, Fukushima M, Kanzaki M, Ohtani T, Sakata Y, Nishi H, Toda K, Sawa Y, Komuro I, Horii T, Iida T, Nakamura S, Takashima S.
- Journal Title
  
  Int J Cardiol.
  
  Volume: 172 Issue: 2 Pages: 288-9
- DOI
  10.1016/j.ijcard.2013.12.197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24890103, KAKENHI-PROJECT-25670271, KAKENHI-PROJECT-25670272
[Journal Article] Switching from carvedilol to bisoprolol ameliorates adverse effects in heart failure patients with dizziness or hypotension.2013
- Author(s)
  Taniguchi T, Ohtani T, Mizote I, Kanzaki M, Ichibori Y, Minamiguchi H, Asano Y, Sakata Y, Komuro I.
- Journal Title
  
  J Cardiol.
  
  Volume: 61 Issue: 6 Pages: 417-22
- DOI
  10.1016/j.jjcc.2013.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591097
[Journal Article] Decreased Mortality Associated with Statin Treatment in Patients with Acute Myocardial Infarction and Lymphotoxin- C804A Polymorphism.2013
- Author(s)
  Suna Shinichiro
- Journal Title
  
  Atherosclerosis
  
  Volume: 227 Issue: 2 Pages: 373-379
- DOI
  10.1016/j.atherosclerosis.2013.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390162, KAKENHI-PROJECT-22590827, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-25350910
[Journal Article] Evaluation of intra-mitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2013
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Tkafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y and Takashima S
- Journal Title
  
  PNAS
  
  Volume: 111 Issue: 1 Pages: 273-278
- DOI
  10.1073/pnas.1318547111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24570149, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PROJECT-24790917, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25461119, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26461108
[Journal Article] Dipeptidyl-peptidase IV inhibition improves pathophysiology of heart failure and increases survival rate in pressure-overloaded mice.2013
- Author(s)
  Takahashi A, Asakura M, Ito S, Min KD, Shindo K, Yan Y, Liao Y, Yamazaki S, Sanada S, Asano Y, Ishibashi-Ueda H, Takashima S, Minamino T, Asanuma H, Mochizuki N, Kitakaze M
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 304(10) Issue: 10 Pages: H1361-H1369
- DOI
  10.1152/ajpheart.00454.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590817, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097
[Journal Article] Dipeptidyl-Peptidase IV Inhibition Improves Pathophysiology of Heart Failure and Increases Survival Rate in Pressure-Overloaded Mice2013
- Author(s)
  Takahashi A, Asakura M, Ito S, Min KD, Shindo K, Yan Y, Liao Y, Yamazaki S, Sanada S, Asano Y, Ueda H, Takashima S, Minamino T, Asanuma H, Mochizuki N, Kitakaz M
- Journal Title
  
  Am J Phyisol
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591096
[Journal Article] Liposomal amiodarone augments anti-arrhythmic effects and reduces hemodynamic adverse effects in an ischemia/reperfusion rat model.2013
- Author(s)
  Takahama H, Shigematsu H, Asai T, Matsuzaki T, Sanada S, Fu HY, Okuda K, Yamato M, Asanuma H, Asano Y, Asakura M, Oku N, Komuro I, Kitakaze M, Minamino T.
- Journal Title
  
  Cardiovasc Drugs Ther.
  
  Volume: 27 Issue: 2 Pages: 125-132
- DOI
  10.1007/s10557-012-6437-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25460041
[Journal Article] H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.2012
- Author(s)
  Yoshida A, Asanuma H, Sasaki H, Sanada S, Yamazaki S, Asano Y, Shinozaki Y, Mori H, Shimouchi A, Sano M, Asakura M, Minamino T, Takashima S, Sugimachi M, Mochizuki N, Kitakaze M.
- Journal Title
  
  Cardiovasc Drugs Ther.
  
  Volume: 26 Pages: 217-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591097
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer.2012
- Author(s)
  K. Nishikawa, T. Asai, H. Shigematsu, K. Shimizu, H. Kato, Y. Asano, S. Takashima, E. Mekada, N. Oku, T. Minamino
- Journal Title
  
  J. Control. Release
  
  Volume: 160 Issue: 2 Pages: 274-280
- DOI
  10.1016/j.jconrel.2011.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-22890104, KAKENHI-PROJECT-23240126, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Journal Article] The impact of cardiac resynchronization therapy in an end-stage heart failure patient with a left ventricular assist device as a bridge to recovery. A case report2011
- Author(s)
  Muratsu J, Hara M, Mizote I, Asano Y, Sakata Y, Saito S, Matsumiya G, Sawa Y, Komuro I
- Journal Title
  
  Int Heart J
  
  Volume: 52(4) Pages: 246-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] A Case Report2011
- Author(s)
  Muratsu J, Hara M, Mizote I, Asano Y, Sakata Y, Saito S, Matsumiya G, Sawa Y, Komuro I
- Journal Title
  
  Int. Heart J.
  
  Volume: 52 Issue: 4 Pages: 246-247
- DOI
  10.1536/ihj.52.246
- NAID
  130000971171
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer2011
- Author(s)
  Nishikawa K, Asai T, Shigematsu H, Shimizu K, Kato H, Asano Y, Takashima S, Mekada E, Oku N, Minamino T
- Journal Title
  
  J Control Release
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] A case of non-cardiogenic acute pulmonary edema in a patient with POEMS syndrome-associated pulmonary arterial hypertension2011
- Author(s)
  Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I
- Journal Title
  
  Ann Hematol
  
  Volume: 90(4) Pages: 489-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] Clinical impact of off-label cardiac resynchronization therapy in end-stage heart failure patients on continuous intravenous inotrope2011
- Author(s)
  Hara M, Mizuno H, Mizote I, Nakatani D, Asano Y, Sakata Y, Nanto S, Komuro I
- Journal Title
  
  Clin Cardiol
  
  Volume: 34(11) Pages: 714-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes.2010
- Author(s)
  Sawada T, Minamino T, Fu HY, Asai M, Okuda K, Isomura T, Yamazaki S, Asano Y, Okada K, Tsukamoto O, Sanada S, Asanuma H, Asakura M, Takashima S, Kitakaze M, Komuro I.
- Journal Title
  
  Journal of molecular and cellular cardiology. 48(6)
  
  Pages: 1280-1289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1(HP1)2010
- Author(s)
  Higo S, Asano Y, Kato H, Yamazaki S, Nakano A, Tsukamoto O, Seguchi O, Asai M, Asakura M, Asanuma H, Sanada S, Minamino T, Komuro I, Kitakaze M, Takashima S
- Journal Title
  
  J Biol Chem
  
  Volume: 285(41) Pages: 31337-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/ CRE-like element in cardiomyocytes2010
- Author(s)
  Sawada T, Minamino T, Fu HY, Asai M, Okuda K, Isomura T, Yamazaki S, Asano Y, Okada K, Tsukamoto O, Sanada S, Asanuma H, Asakura M, Takashima S, Kitakaze M, Komuro I
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 48(6) Pages: 1280-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.2010
- Author(s)
  Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, Asano Y, Seguchi O, Higo S, Shintani Y, Asanuma H, Asakura M, Minamino T, Kaibuchi K, Mochizuki N, Kitakaze M, Takashima S.
- Journal Title
  
  Nat Cell Biol. 12(6)
  
  Pages: 583-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Ablation of C/ EBP Homologous Protein Attenuates Endoplasmic Reticulum-Mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload2010
- Author(s)
  Fu HY, Okada KI, Liao Y, Tsukamoto O, Isomura T, Asai M, Sawada T, Okuda K, Asano Y, Sanada S, Asanuma H, Asakura M, Takashima S, Komuro I, Kitakaze M, Minamino T
- Journal Title
  
  Circulation
  
  Volume: 122(4) Pages: 361-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload.2010
- Author(s)
  Fu HY, Okada K, Liao Y, Tsukamoto O, Isomura T, Asai M, Sawada T, Okuda K, Asano Y, Sanada S, Asanuma H, Asakura M, Takashima S, Komuro I, Kitakaze M, Minamino T.
- Journal Title
  
  Circulation. 122(4)
  
  Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Sildenafil and steroid therapy effectively improved POEMS syndromeassociated pulmonary arterial hypertension2010
- Author(s)
  Shimomura Y, Hara M, Mizote I, Nakaoka Y, Tanaka H, Asano Y, Sakata Y, Komuro I
- Journal Title
  
  Int J Hematol
  
  Volume: 92(5) Pages: 774-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1).2010
- Author(s)
  Higo S, Asano Y, Kato H, Yamazaki S, Nakano A, Tsukamoto O, Seguchi O, Asai M, Asakura M, Asanuma H, Sanada S, Minamino T, Komuro I, Kitakaze M, Takashima S.
- Journal Title
  
  The Journal of biological chemistry. 285(41)
  
  Pages: 31337-31347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation2010
- Author(s)
  Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, Asano Y, Seguchi O, Higo S, Shintani Y, Asanuma H, Asakura M, Minamino T, Kaibuchi K, Mochizuki N, Kitakaze M, Takashima S
- Journal Title
  
  Nature Cell Biology
  
  Volume: 12(6) Pages: 583-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.2009
- Author(s)
  Asai M, Tsukamoto O, Minamino T, Asanuma H, Fujita M, Asano Y, Takahama H, Sasaki H, Higo S, Asakura M, Takashima S, Hori M, Kitakaze M.
- Journal Title
  
  Journal of molecular and cellular cardiology. 46(4)
  
  Pages: 452-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Natriuretic peptides enhance the production of adiponectin in human adipocytes and in patients with chronic heart failure2009
- Author(s)
  Tsukamoto O, Fujita M, Kato M, Yamazaki S, Asano Y, Ogai A, Okazaki H, Asai M, Nagamachi Y, Maeda N, Shintani Y, Minamino T, Asakura M, Kishimoto I, Funahashi T, Tomoike H, Kitakaze M
- Journal Title
  
  J Am Coll Cardiol
  
  Volume: 53(22) Pages: 2070-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts2009
- Author(s)
  Asai M, Tsukamoto O, Minamino T, Asanuma H, Fujita M, Asano Y, Takahama H, Sasaki H, Higo S, Asakura M, Takashima S, Hori M, Kitakaze M
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 46(4) Pages: 452-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689022
[Journal Article] Identification of a novel substrate for TNFalpha-induced kinase NUAK2.2008
- Author(s)
  Yamamoto H, Takashima S, Shintani Y, Yamazaki S, Seguchi O, Nakano A, Higo S, Kato H, Liao Y, Asano Y, Minamino T, Matsumura Y, Takeda H, Kitakaze M.
- Journal Title
  
  Biochem Biophys Res Commun. 365(3)
  
  Pages: 541-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Higher mortality in heterozygous neuropilin-1 mice after cardiac pressure overload.2008
- Author(s)
  Li F, Zhao H, Liao Y, Takashima S, Asano Y, Shintani Y, Hori M, Kitakaze M.
- Journal Title
  
  Biochem Biophys Res Commun. 370(2)
  
  Pages: 317-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Identification of p32 as a novel substrate for ATM in heart.2008
- Author(s)
  Kato H, Takashima S, Asano Y, Shintani Y, Yamazaki S, Seguchi O, Yamamoto H, Nakano A, Higo S, Ogai A, Minamino T, Kitakaze M, Hori M.
- Journal Title
  
  Biochem Biophys Res Commun. 366(4)
  
  Pages: 885-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress.2008
- Author(s)
  Zhao H, Liao Y, Minamino T, Asano Y, Asakura M, Kim J, Asanuma H, Takashima S, Hori M, Kitakaze M.
- Journal Title
  
  Hypertens Res. 31(10)
  
  Pages: 1977-1987
- NAID
  10024827861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Patent] 遺伝性徐脈性不整脈治療薬2020
- Inventor(s)
  朝野仁裕、高島成二、山田憲明、山下徹
- Industrial Property Rights Holder
  朝野仁裕、高島成二、山田憲明、山下徹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03652
[Patent] 心不全感受性エンハンサーを含む遺伝子治療用ベクター2020
- Inventor(s)
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Holder
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-206823
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03652
[Patent] 遺伝性徐脈性不整脈治療薬2019
- Inventor(s)
  朝野仁裕、高島成二、山田憲明、山下徹
- Industrial Property Rights Holder
  朝野仁裕、高島成二、山田憲明、山下徹
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03652
[Patent] 心不全感受性エンハンサーを含む遺伝子治療用ベクター2019
- Inventor(s)
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Holder
  朝野仁裕、高島成二、松岡研、塚本蔵、木岡秀隆
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-206823
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03652
[Patent] 遺伝性徐脈性不整脈治療薬2019
- Inventor(s)
  朝野仁裕、髙島成二、山田憲明、山下徹
- Industrial Property Rights Holder
  朝野仁裕、髙島成二、山田憲明、山下徹
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19547
[Patent] 遺伝性徐脈性不整脈治療薬2018
- Inventor(s)
  朝野仁裕、髙島成二、山田憲明、山下徹
- Industrial Property Rights Holder
  朝野仁裕、髙島成二、山田憲明、山下徹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-247919
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19547
[Patent] 心不全の重症度を無侵襲で経時的に正確に定量評価可能なマウス2013
- Inventor(s)
  高島成二, 朝野仁裕, 松岡研, 塚本蔵, 北風政史
- Industrial Property Rights Holder
  高島成二, 朝野仁裕, 松岡研, 塚本蔵, 北風政史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-228824
- Filing Date
  2013-09-02
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 左室収縮能低下を伴う重症心不全に移行しMYH7 R453バリアントが同定された肥大型心筋症の3症例2023
- Author(s)
  内藤進, 肥後修一朗, 亀田聡士, 小川翔, 田端智香, 赤澤康裕, 中村大輔, 中本敬, 世良英子, 藏本勇希, 朝野仁裕, 彦惣俊吾, 宮川繁, 坂田泰史
- Organizer
  第9回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 心臓疾患に対するAAVベクターを用いた遺伝子治療開発2022
- Author(s)
  朝野仁裕
- Organizer
  ACTjapanフォーラム
- Data Source
  KAKENHI-PROJECT-23K24328
[Presentation] 心筋症の遺伝子診断の標準化とAAVベクターによる遺伝子治療戦略2022
- Author(s)
  朝野仁裕
- Organizer
  第70回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24328
[Presentation] 第26回日本心不全学会2022
- Author(s)
  朝野仁裕
- Organizer
  ゲノム情報を活かした心筋症医療
- Data Source
  KAKENHI-PROJECT-23K24328
[Presentation] 分子機能による層別化を目的とした心筋症疾患iPS細胞ライブラリーの構築2022
- Author(s)
  肥後修一朗, 木岡秀隆, 李鍾國, 彦惣俊吾, 朝野仁裕, 宮川繁, 坂田泰史
- Organizer
  第26回日本心不全学会学術集会シンポジウムゲノム情報を活かした心筋症医療
- Invited
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] 心筋症のゲノム解析　～診療につなげる実践的解析に必要なもの～2022
- Author(s)
  朝野仁裕
- Organizer
  第8回日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-23K24328
[Presentation] 悪性心室性頻拍と重症心不全を特徴とする日本におけるホスホランバン p.Arg14del心筋症の臨床像2021
- Author(s)
  田端智香,藏本勇希,大谷朋仁,宮脇大,宮下洋平,世良英子,木岡秀隆,肥後修一朗,朝野仁裕,彦惣俊吾,坂田泰史
- Organizer
  第25回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02915
[Presentation] シンポジウム-2：遺伝子治療開発の最前線遺伝性心筋症に対する新たな遺伝子治療法の開発2021
- Author(s)
  朝野仁裕
- Organizer
  第34回日本動物細胞工学会2021年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] シンポジウム「心不全ゲノム医療の最前線」疾患ゲノム解析による心不全の層別化とゲノム医療への応用2021
- Author(s)
  朝野仁裕
- Organizer
  第25回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 臨床・かかりつけ医セッション心不全の原因を知り、治療へつなぐ情報の入手2021
- Author(s)
  朝野仁裕
- Organizer
  第69回日本心臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] シンポジウム6：心筋症の分子機序臨床にとどける心筋症のゲノム研究2021
- Author(s)
  朝野仁裕
- Organizer
  第7回日本心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 臨床における心筋症ゲノム解析研究2020
- Author(s)
  朝野仁裕
- Organizer
  第7回日本心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Genome Analysis and Genomic Medicine in Cardiomyopathy2020
- Author(s)
  Yoshihiro Asano
- Organizer
  第84回日本循環器学会学術集会（開催延期）
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Genome Analysis and Genomic Medicine in Cardiomyopathy2020
- Author(s)
  Yoshihiro Asano
- Organizer
  第84回日本循環器学会学術集会（開催延期）
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Application of Genome Analysis and Information to Diagnosis and Treatment of Cardiomyopathy2020
- Author(s)
  Yoshihiro Asano
- Organizer
  The 85th Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Elucidation of the Mechanism of KACh Channelopathy -New Stratification of the Disease, and Development of Treatment2020
- Author(s)
  Yoshihiro Asano
- Organizer
  The 85th Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 心筋症の臨床遺伝子診断とバリアントデータベースの利用による新規病態解明2020
- Author(s)
  朝野仁裕
- Organizer
  第 6 回日本心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Development of Gene Therapy for Hereditary Cardiomyopathy2020
- Author(s)
  Yoshihiro Asano
- Organizer
  第24回日本心不全学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 臨床にとどける心筋症のゲノム研究2020
- Author(s)
  朝野仁裕
- Organizer
  第24回日本心不全学会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Identification of Novel Genes for Cardiomyopathies, Elucidation of Pathogenesis, and Development of New Therapeutic Strategies for Genomic Medicine2020
- Author(s)
  Yoshihiro Asano
- Organizer
  The 85th Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 心筋症の遺伝子診断における問題点と解決策2019
- Author(s)
  朝野仁裕
- Organizer
  第23回日本心不全学会学術集会、シンポジウム14「心筋症と遺伝子診断」
- Invited
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] Genomic medicine in sinus bradycardia and a strategy for development of a novel targeted therapy2019
- Author(s)
  Yoshihiro Asano
- Organizer
  2019 XXIII ISHR WORLD CONGRESS（国際心臓研究会世界大会）Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] ミート・ザ・エキスパート 11 心筋症の新しい話題 "Application of Whole Exome Sequencing Data for Detection of Large Genomic Rearrangements in Cardiomyopathy"2019
- Author(s)
  朝野仁裕
- Organizer
  The 83rd Annual Scientific Meeting of the Japanese Circulation Society
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Cardiomyopathies: genetic causes and precision medicine2019
- Author(s)
  Yoshihiro Asano
- Organizer
  ESC CONGRESS 2019（欧州心臓病学会年会）Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Japan Heart Foundation the 44th Sato Memorial Award "Elucidation of the Molecular Mechanism, Establishment of Diagnostic Method, and Drug Development by Omics Analysis of Intractable Cardiovascular Diseases"2019
- Author(s)
  朝野仁裕
- Organizer
  The 83rd Annual Scientific Meeting of the Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Symposium 17. Precision Medicine in Inherited Arrhythmias "New Insights into the Therapeutic Potential of a KACh Channel in Hereditary Sinus Bradycardia"2019
- Author(s)
  朝野仁裕
- Organizer
  The 83rd Annual Scientific Meeting of the Japanese Circulation Society
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Genomic medicine in sinus bradycardia and a strategy for development of a novel targeted therapy2019
- Author(s)
  Yoshihiro Asano
- Organizer
  2019 XXIII ISHR WORLD CONGRESS（国際心臓研究会世界大会）Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] Cardiomyopathies: genetic causes and precision medicine2019
- Author(s)
  Yoshihiro Asano
- Organizer
  ESC CONGRESS 2019（欧州心臓病学会年会）Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03652
[Presentation] 心筋症の遺伝子診断における問題点と解決策2019
- Author(s)
  朝野仁裕
- Organizer
  第23回日本心不全学会学術集会シンポジウム14「心筋症と遺伝子診断」
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] プレナリーセッション：多層化する循環器ゲノム研究（Multilayered Cardiovascular Genetics） Clinical Application of Whole Exome Sequencing inSinus Bradycardia and a Strategy for Development of aNovel Targeted Therapy2018
- Author(s)
  朝野仁裕
- Organizer
  第82回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] シンポジウム3. ゲノム情報を心筋症診療に生かす「拡張型心筋症における全エクソームシーケンスの応用と展望」2018
- Author(s)
  朝野仁裕
- Organizer
  第4回心筋症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] 第6回日本心不全学会学術賞受賞講演：多層オミックス解析による心不全分子基盤の解明とゲノム医療を目指す診断治療法の開発2018
- Author(s)
  朝野仁裕
- Organizer
  第22回日本心不全学会
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] シンポジウム2「循環器領域における遺伝子診断と遺伝カウンセリング」希少循環器疾患におけるゲノム解析による遺伝子診断2018
- Author(s)
  朝野仁裕
- Organizer
  第22回日本心不全学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] 特別企画8「我が国における循環器病研究の現状と将来展望」2018
- Author(s)
  朝野仁裕
- Organizer
  第22回日本心不全学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] シンポジウム5. Practice and Application of Whole Exome Sequencing in Hereditary Heart Disease2018
- Author(s)
  朝野仁裕
- Organizer
  The 2nd JCS Council Forum on Basic Cardiovascular Research
- Invited
- Data Source
  KAKENHI-PROJECT-18K19547
[Presentation] 心筋症のエクソーム解析による原因変異検索2017
- Author(s)
  多久和綾子、朝野仁裕
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] De novo BNP enhancer region (CR9) works as the mechanical stress-responsive element of Nppb2017
- Author(s)
  宮下洋平、朝野仁裕
- Organizer
  第1回日本循環器学会基礎研究フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 教育セッション：ゲノム診療が循環器医に求めるもの2017
- Author(s)
  朝野仁裕
- Organizer
  第123回日本循環器学会近畿地方会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 特別講演：「次世代シークエンサーから見えてくる循環器疾患の病態」循環器希少難病に対する疾患ゲノム解析の実際と臨床応用2017
- Author(s)
  朝野仁裕
- Organizer
  第20回小児心血管分子医学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] BNPエンハンサー領域に着目した新規心毒性評価系の開発2017
- Author(s)
  宮下洋平、朝野仁裕
- Organizer
  Molecular Cardiovascular Metabolic Conference
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 心筋症症例の全エクソームシーケンスによる疾患変異解析（Genetic　Analysis for a Cardiomyopathy population with Whole Exome Sequencing）2017
- Author(s)
  多久和綾子、朝野仁裕
- Organizer
  第62回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 難治性遺伝性循環器疾患における全エクソーム解析と家系症例に対する臨床遺伝子診断の試み2016
- Author(s)
  朝野仁裕
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 教育セッション（６）「臨床医が学ぶ基礎医学講座」「疾患ゲノム解析の進化と臨床への応用」2015
- Author(s)
  朝野仁裕
- Organizer
  第19回日本心不全学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] 心筋症の遺伝子・分子医学・基礎と臨床「遺伝性心筋症における新たなゲノム情報解析による変異同定法の開発」2015
- Author(s)
  朝野仁裕
- Organizer
  第１回心筋症研究会
- Place of Presentation
  東京
- Year and Date
  2015-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-15K09139
[Presentation] G0/G1 Switch Gene 2 Promotes Mitochondrial ATP Production and Protects Cardiomyocytes from the Energy Crisis under Hypoxia2013
- Author(s)
  Hidetaka Kioka, Yoshihiro Asano, Seiji Takashima, Masafumi Kitakaze, Issei Komuro
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] Quantitative ChIP-Sequence Analysis Reveals the Differentially Altered Active Epigenomic States in Murine Pressure-Overloaded Failing Hearts2012
- Author(s)
  Higo Shuichiro, Asano Yoshihiro, Takashima Seiji, Kitakaze Masafumi, Komuro Issei
- Organizer
  The 29th Annual Meeting of the International Society for Heart Research Japanese Section
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 「パネルディスカッション　再生医療に貢献する技術」心筋細胞の可塑性を判断する病理学的臨床指標の開発2012
- Author(s)
  朝野　仁裕
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 心不全におけるクロマチンリモデリング制御と細胞機能維持機構の解明、成人病の病因・病態の解明に関する研究助成2011
- Author(s)
  朝野仁裕
- Organizer
  第17回研究発表会
- Place of Presentation
  大阪
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-21689022
[Presentation] 心不全の新しい病態解析法新しい心筋viability評価法の開発による治療抵抗性心不全へのアプローチ2011
- Author(s)
  朝野仁裕
- Organizer
  大阪ハートクラブ
- Place of Presentation
  大阪
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21689022
[Presentation] Evidence for dynamic changes of chromatin state at the stress-induced gene locus in cardiomyocytes2011
- Author(s)
  Shuichiro Higo, Yoshihiro Asano, Seiji Takashima, Issei Komuro
- Organizer
  Molecular Cardiovascular Conference
- Place of Presentation
  北海道
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21689022
[Presentation] 心不全におけるクロマチンリモデリング制御と細胞機能維持機構の解明2011
- Author(s)
  朝野仁裕
- Organizer
  成人病の病因・病態の解明に関する研究助成第17回研究発表会
- Place of Presentation
  大阪
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-21689022
[Presentation] 心不全の新しい病態解析法新しい心筋viability評価法の開発による治療抵抗性心不全へのアプローチ2011
- Author(s)
  朝野仁裕
- Organizer
  大阪ハートクラブ学術講演会
- Place of Presentation
  大阪
- Year and Date
  2011-05-18
- Data Source
  KAKENHI-PROJECT-21689022
[Presentation] Heart Failure Specific Enhancer Regulates the Expression of Natriuretic Peptides
- Author(s)
  Ken Matsuoka, Yoshihiro Asano
- Organizer
  第17 回日本心不全学会学術集会
- Place of Presentation
  埼玉大宮
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 心筋細胞核クロマチン形態は拡張型心筋症患者の予後不良予測因子となりうる
- Author(s)
  神崎万智子、朝野仁裕
- Organizer
  第35 回心筋生検研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] Comprehensive quantitative epigenome mapping reveals the differential induction of histone H3 lysine 4 trimethylation marks in pressure-overloaded murine hearts
- Author(s)
  Shuichiro Higo,Yoshihiro Asano, Seiji Takashima, Masafumi Kitakaze, Issei Komuro
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles、USA
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 重症慢性心不全の病態可塑性判断を可能にする心臓病理エピゲノム診断指標の開発
- Author(s)
  朝野仁裕
- Organizer
  第62回日本心臓病学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2014-09-26 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] A New Diagnostics Method for Refractory Heart Failure
- Author(s)
  朝野仁裕
- Organizer
  第31回国際心臓研究学会（ISHR）日本部会
- Place of Presentation
  名古屋
- Year and Date
  2015-01-10 – 2015-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] Research Strategies of Whole Exome Sequencing ~ Practical Approaches for 110 Patients (32 families) with Hereditary Cardiomyopathy and Arrhythmia ~
- Author(s)
  Yoshihiro Asano
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] 拡張型心筋症の病態不可逆性を予測する新規心臓エピゲノム診断指標の開発
- Author(s)
  朝野仁裕
- Organizer
  第44回日本心脈管作動物質学会
- Place of Presentation
  高松
- Year and Date
  2015-02-06 – 2015-02-07
- Invited
- Data Source
  KAKENHI-PROJECT-24591097
[Presentation] Morphometric and Quantitative Analysis in Cardiomyocyte’s Nucleus were Associated with Poor Outcome in Patients with Idiopathic Dilated Cardiomyopathy
- Author(s)
  Machiko Kanzaki, Yoshihiro Asano
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591097

1. TSUKAMOTO Osamu (80589151)

# of Collaborated Projects: 11 results

# of Collaborated Products: 10 results
2. HIGO Schuichiro (00604034)

# of Collaborated Projects: 6 results

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# of Collaborated Projects: 4 results

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23. TASHIRO Shimon (50548550)

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24. Kubota Kayoko (50709863)

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# of Collaborated Products: 5 results
43. Yan Yi

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44. YAMASHITA Motozo

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45. KITAGAKI Jirouta

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46. ASAKURA Masanori

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47. MIN Kyung-Duk

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48. YOSHITOMI Toru

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49. ITO Shin

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50. YAGASAKI Hideaki

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51. TAKAHAMA Hiroyuki

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52. HAGIWARA nobuhisa

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53. SHIGA tsuyoshi

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ASANO YOSHIHIRO 朝野 仁裕

ASANO Yoshihiro 朝野 仁裕

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Elucidation of the pathophysiology of cardiomyopathy and exploration of new drug targets for realization of genomic medicinePrincipal Investigator

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全ゲノム解析基盤による機能・情報統合解析と新規心筋症遺伝子の同定および機序解明Principal Investigator

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Identification of Novel Molecular Targets and Drug Development by Genomic and Multilayer-Omics Analysis of Hereditary CardiomyopathiesPrincipal Investigator

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Elucidation of the pathological mechanism of KACh channelopathy and development of novel heart rate modulating drugPrincipal Investigator

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Elucidation of the irreversible mechanism of severe heart failure using biological monitoring murine heart failure modelPrincipal Investigator

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ASANO YOSHIHIRO 朝野仁裕

ASANO Yoshihiro 朝野仁裕

[Book] 月刊心臓（公益財団法人日本心臓財団）HEART's Selection　拡張型心筋症の精密医療　5．拡張型心筋症をゲノムで層別化する2021

[Book] 月刊心臓　HEART's Selection　拡張型心筋症の精密医療　拡張型心筋症をゲノムで層別化する2021

[Book] 循環器内科　核膜蛋白の変異によってひき起こされる不整脈原性心筋症の新たな分子機序2021

[Book] 新心臓病学　第7章心筋疾患・心膜疾患　不整脈原性右室心筋症2020