Minamino Tetsuo 南野哲男

… Alternative Names

Researcher Number	30379234
Other IDs
Affiliation (Current)	2020: 香川大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020: 香川大学, 医学部, 教授 2016 – 2018: 香川大学, 医学部, 教授 2015: 大阪大学, 大学院医学系研究科, 准教授 2014 – 2015: 大阪大学, 医学(系)研究科(研究院), 准教授 2012 – 2013: 大阪大学, 医学(系)研究科(研究院), 講師 … More
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine / Basic Section 53020:Cardiology-related Except Principal Investigator Circulatory organs internal medicine / Cell biology / Cardiovascular medicine / General applied physics / Basic Section 90130:Medical systems-related
Keywords	Principal Investigator 小胞体ストレス / 心不全 / プロテアソーム / 心不全指標 / 心筋虚血 / 動脈硬化 / CHOP / 冠動脈プラーク破綻 / 分子心臓病態学 / 劇症型心筋症 … More Except Principal Investigator 心不全 / 循環器・高血圧 / アデノシン / 生体分子 / 細胞・組織 / 心不全診断 / 心不全治療 / トランスレーショナル研究 / 臨床試験 / 循環器病学 / 小胞体 / 分子シャペロン / 転写誘導 / 膜結合性転写因子 / ノックアウトマウス / 選別輸送 / 還元 / 脂肪滴 / アポリポプロテイン / 組織・細胞 / ゲノム / エピジェネティクス / マイクロアレイ / 遺伝子 / スプライシング / エピゲノム / 細胞核クロマチン / 難治性心不全 / 分子循環器病学 / 臨床循環器 / 慢性心不全 / 自然免疫 / 心筋保護 / 内因性免疫 / G蛋白共役受容体 / 心筋リモデリング / 心筋細胞 / G蛋白共役性受容体 / IL-33 / ST2受容体 / MAPキナーゼ / NF-kB / 心筋肥大 / アポトーシス / 心筋梗塞 / Nitric Oxide / プレコンディショニング / myocardial infarction / heart failure / preconditioning / adenosine / nitric oxide / 増殖因子 / 創薬 / 興奮収縮連関 / 強心剤 / ゼブラフィッシュ / Heart Failure / Growth Factor / drug discovery / contraction-excitation coupling / cardiotonic drug / zebrafish / QCM / バイオセンサー / 蛋白質相互作用 / 無線 / QCMバイオセンサー / MEMSプロセス / アミロイド線維 / 計測工学 / マイクロ・ナノデバイス / 核酸 / 脳神経疾患 / アミロイドβ / 超音波 / フレイル / 高血圧 / 左室肥大 / 左室拡張障害 / 座位心臓超音波検査 / 医療安全 / 要介護 Less

小学生におけるLDL-コレステロールの健診スクリーニングの意義Principal InvestigatorOngoing
- Principal Investigator
  
  南野哲男
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kagawa University
Development of a sitting position ultrasonic examination method for patient safety and its application to evaluation of cardiac function of flail patients and long-term care recipientsOngoing
- Principal Investigator
  
  舛形尚
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kagawa University
Development of next-generation wireless-electroless oscillator biosensors for diagnosis and drug development
- Principal Investigator
  
  Ogi Hirotsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General applied physics
- Research Institution
  Osaka University
Development of antibody-drug conjugate to diagnose and treat vulnerable plaquePrincipal Investigator
- Principal Investigator
  
  MINAMINO TETSUO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kagawa University
  Osaka University
Exploration for Aggravating Process of Heart Failure Induced by Specific Interaction with G-protein-coupled Receptor and Toll-like Receptor
- Principal Investigator
  
  Sanada Shoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Osaka University
Role of ER oxidoreductin-1 in cardiovascular remodelingPrincipal Investigator
- Principal Investigator
  
  MINAMINO TETSUO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
A New Diagnostics Method for Refractory Heart Failure
- Principal Investigator
  
  ASANO YOSHIHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Development of image diagnosis and treatment for fluminant myocarditisPrincipal Investigator
- Principal Investigator
  
  MINAMINO Tetsuo
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Role of splicing variants in heart failure
- Principal Investigator
  
  ASAKURA Masanori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Analysis of molecular mechanism of sensing endoplasmic reticulum stress and effect of failing in the endoplasmic reticulum stress response
- Principal Investigator
  
  MORI Kazutoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Identification and Functional Analysis of Cardiac Specific Singling Molecules and Therapeutic Applications for Cardiovascular Disease
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
新しい概念(エピジェネティクス)を応用した難治性心不全発症分子メカニズムの解明
- Principal Investigator
  
  高島成二
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Translational research of adenosine aiming for diagnosis and treatment of heart failure
- Principal Investigator
  
  MASAFUMI Kitakaze
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
Pathophysiological Role of ER-Ubiquitin/Proteasome System in Cardiovascular RemodelingPrincipal Investigator
- Principal Investigator
  
  MINAMINO Tetsuo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
New therapeutic approach for heart failure using HB-EGF mediated signal transduction
- Principal Investigator
  
  TAKASHIMA Seiji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
The role of ER stress and ubiquitin-proteasome system in the development of heart failruePrincipal Investigator
- Principal Investigator
  
  MINAMINO Tetsuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Experimental and clinical evaluation of cardioprotective effects by adenosine and nitric oxide
- Principal Investigator
  
  HORIO Masatsugu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University

[Book] 小胞体ストレスと心臓病2013
- Author(s)
  南野哲男、小室一成
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-24591096
[Book] 心肥大・心不全と小胞ストレス2008
- Author(s)
  浅井光俊、南野哲男
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19590815
[Book] 心肥大・心不全と小胞体ストレス2008
- Author(s)
  浅井光俊, 南野哲男
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19590815
[Book] Annual Review 循環器2007
- Author(s)
  南野哲男
- Total Pages
  6
- Publisher
  小胞体ストレス
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Book] Cardiac Practice.18、活性酵素と小胞外ストレス2007
- Author(s)
  塚本蔵、南野哲男
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19590815
[Book] Medical Science Digest 33、小胞体ストレスと心血管疾患2007
- Author(s)
  浅井光俊、南野哲男
- Publisher
  北隆館/ニュー・サイエンス社
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Systemic Administration of siRNA with Anti-HB-EGF Antibody-Modified Lipid Nanoparticles for the Treatment of Triple-Negative Breast Cancer2018
- Author(s)
  Okamoto A, Asai T, Hirai Y, Shimizu K, Koide H, Minamino T, Oku N
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Pages: 1495-1504
- DOI
  10.1021/acs.molpharmaceut.7b01055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-17K14519, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-15J11660
[Journal Article] A novel therapy for acute autoimmune myocarditis with nano-sized liposomal FK5062017
- Author(s)
  Okuda K, Fu HY, Matsuzaki T, Araki R, Tsuchida S, Thanikachalam PV, Fukuta T, Asai T, Yamato M, Sanada S, Asanuma H, Asano Y, Asakura M, Hanawa H, Hao H, Oku N, Takashima S, Kitakaze M, Sakata Y, Minamino T.
- Journal Title
  
  PLoS One
  
  Volume: 11
- DOI
  10.1371/journal.pone.0160944
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-15K12542
[Journal Article] Development of a novel one-step production system for injectable liposomes under GMP.2017
- Author(s)
  Araki Ryo、Matsuzaki Takashi、Nakamura Ayumi、Nakatani Daisaku、Sanada Shoji、Fu Hai Ying、Okuda Keiji、Yamato Masaki、Tsuchida Shota、Sakata Yasushi、Minamino Tetsuo
- Journal Title
  
  Pharmaceutical Development and Technology
  
  Volume: 10 Pages: 1-6
- DOI
  10.1080/10837450.2017.1290106
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-15K12542
[Journal Article] RNA aptamer binds heparin-binding epidermal growth factor-like growth factor with high affinity and specificity and neutralizes its activity2017
- Author(s)
  Masaki Yamato, Tetsuo Minamino, yamato masaki, Takashi Matsuzaki, Ryo Araki, Shota Tsuchida, Keiji Okuda, Hai Ying Fu, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Hiroomi Torii, Kentaro Noi, Hirotsugu Ogi, Ryo Iwamoto, Eisuke Mekada, Seiji Takashima, Yasushi Sakata, Masafumi Kitakaze
- Journal Title
  
  International Journal of Gerontology
  
  Volume: 11 Pages: 191-196
- DOI
  10.1016/j.ijge.2017.03.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07046, KAKENHI-PROJECT-15H03587
[Journal Article] Btg2 is a Negative Regulator of Cardiomyocyte Hypertrophy through a Decrease in Cytosolic RNA2016
- Author(s)
  Masumura Y, Higo S, Asano Y, Kato H, Yan Y, Ishino S, Tsukamoto O, Kioka H, Hayashi T, Shintani Y, Yamazaki S, Minamino T, Kitakaze M, Komuro I, Takashima S, Sakata Y.
- Journal Title
  
  Science Report
  
  Volume: 6 Pages: 28592-28592
- DOI
  10.1038/srep28592
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15K08271, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K09139, KAKENHI-PROJECT-16K09500, KAKENHI-PROJECT-16K09501
[Journal Article] Histone Deacetylase Inhibitor Phenylbutyrate Exaggerates Heart Failure in Pressure Overloaded Mice independently of HDAC inhibition.2016
- Author(s)
  Ma J, Luo T, Zeng Z, Fu H, Asano Y, Liao Y, Minamino T, Kitakaze M.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 34036-34036
- DOI
  10.1038/srep34036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-15K09139
[Journal Article] Identification of the Mtus1 Splice Variant as a Novel Inhibitory Factor Against Cardiac Hypertrophy2016
- Author(s)
  Ito S, Asakura M, Liao Y, Min KD, Takahashi A, Shindo K, Yamazaki S, Tsukamoto O, Asanuma H, Mogi M, Horiuchi M, Asano Y, Sanada S, Minamino T, Takashima S, Mochizuki N, Kitakaze M.
- Journal Title
  
  J. Am. Heart. Assoc
  
  Volume: 5
- DOI
  10.1161/jaha.116.003521
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K09111
[Journal Article] Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction2016
- Author(s)
  Fu HY, Sanada S, Matsuzaki T, Liao Y, Okuda K, Yamato M, Tsuchida S, Araki R, Asano Y, Asanuma H, Asakura M, French BA, Sakata Y, Kitakaze M, Minamino T.
- Journal Title
  
  Circulation Research
  
  Volume: 118 Pages: 798-809
- DOI
  10.1161/circresaha.115.307604
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K12542, KAKENHI-PROJECT-15H04821
[Journal Article] An interaction between glucagon-like peptide-1 and adenosine contributes to cardioprotection of a dipeptidyl peptidase 4 inhibitor from myocardial ischemia-reperfusion injury.2015
- Author(s)
  Ihara M, Asanuma H, Yamazaki S, Kato H, Asano Y, Shinozaki Y, Mori H, Minamino T, Asakura M, Sugimachi M, Mochizuki N, Kitakaze M.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: in press Pages: 1287-1297
- DOI
  10.1152/ajpheart.00835.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-15K19378, KAKENHI-PROJECT-15H04821
[Journal Article] Higd1a is a positive regulator of Cytochrome c Oxidase2015
- Author(s)
  T. Hayashi, Y. Asano, Y. Shintani, H. Aoyama, H. Kioka, O. Tsukamoto, M. Hikita, K. Shinzawa-Itoh, K. Takajuji, S. Higo, H. Kato, S. Yamazaki, K. Matsuoka, A. Nakano, H. Asanuma, M. Asakura, T. Minamino, Y. Goto, T. Ogura, M. Kitakaze, I. Komuro, Y. Sakata, T. Tsukihara, S. Yoshikawa, S. Takashima
- Journal Title
  
  Proc Natl Acad Sci U SA
  
  Volume: 112 Pages: 1553-1553
- DOI
  10.1073/pnas.1419767112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24350086, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PUBLICLY-25109540, KAKENHI-PROJECT-25860599, KAKENHI-PUBLICLY-26104532, KAKENHI-PROJECT-26291033, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26670402, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-25461119
[Journal Article] Carperitide induces coronary vasodilation and limits infarct size in canine ischemic hearts: role of NO.2015
- Author(s)
  Asanuma H, Sanada S, Asakura M, Asano Y, Kim J, Shinozaki Y, Mori H, Minamino T, Takashima S,Kitakaze M.
- Journal Title
  
  Hypertens Res
  
  Volume: 37(8) Pages: 716-23
- DOI
  10.1038/hr.2014.70
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-26461134
[Journal Article] Augmented AMPK activity 1 inhibits cell migration by phosphorylating the novel substrate Pdlim52015
- Author(s)
  Yan Y, Tsukamoto O, Nakano A, Kato H, Kioka H, Ito N, Higo S, Yamazaki S, Shintani Y, Matsuoka K, Liao Y, Asanuma H, Asakura M, Takafuji K, Minamino T, Asano Y, Kitakaze M, Takashima S.
- Journal Title
  
  Ｎature Ｃommunications
  
  Volume: 6 Pages: 0-0
- DOI
  10.1038/ncomms7137
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26860558, KAKENHI-PROJECT-26860559, KAKENHI-PROJECT-15K09111, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-25461119
[Journal Article] Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing hear2014
- Author(s)
  Matsuoka K, Asano Y, Higo S, Tsukamoto O, Yan Y, Yamazaki S, Matsuzaki T, Kioka H, Kato H, Uno Y, Asakura M, Asanuma H, Minamino T, Aburatani H, Kitakaze M, Komuro I, Takashima S.
- Journal Title
  
  FASEB J
  
  Volume: 28(4) Pages: 1870-1870
- DOI
  10.1096/fj.13-245522
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24790757, KAKENHI-PUBLICLY-25118709, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26253049, KAKENHI-PROJECT-26461108, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-26860559
[Journal Article] Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation2014
- Author(s)
  Kioka H, Kato H, Fujikawa M, Tsukamoto O, Suzuki T, Imamura H, Nakano A, Higo S, Yamazaki S, Matsuzaki T, Tkafuji K, Asanuma H, Asakura M, Minamino T, Shintani Y, Yoshida M, Noji H, Kitakaze M, Komuro I, Asano Y and Takashima S
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America
  
  Volume: 111 Pages: 273-273
- DOI
  10.1073/pnas.1318547111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PROJECT-23227006, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24570149, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-24657101, KAKENHI-PROJECT-24790757, KAKENHI-PROJECT-24790917, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25253047, KAKENHI-PROJECT-25461119, KAKENHI-PROJECT-25860599, KAKENHI-PROJECT-26461108
[Journal Article] Decreased mortality associated with statin treatment in patients with acute myocardial infarction and lymphotoxin-alpha C804A polymorphism.2013
- Author(s)
  Suna Shinichiro
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 227 Pages: 373-379
- DOI
  10.1016/j.atherosclerosis.2013.01.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390162, KAKENHI-PROJECT-22590827, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-25350910
[Journal Article] Dipeptidyl-Peptidase IV Inhibition Improves Pathophysiology of Heart Failure and Increases Survival Rate in Pressure-Overloaded Mice2013
- Author(s)
  Takahashi A, Asakura M, Ito S, Min KD, Shindo K, Yan Y, Liao Y, Yamazaki S, Sanada S, Asano Y, Ueda H, Takashima S, Minamino T, Asanuma H, Mochizuki N, Kitakaz M
- Journal Title
  
  Am J Phyisol
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591096
[Journal Article] Dipeptidyl-Peptidase IV Inhibition Improves Pathophysiology of Heart Failure and Increases Survival Rate in Pressure-Overloaded Mice.2013
- Author(s)
  Takahashi A, Asakura M, Ito S, Min KD, Shindo K, Yan Y, Liao Y, Yamazaki S, Sanada S, Asano Y, Ishibashi-Ueda H, Takashima S, Minamino T, Asanuma H, Mochizuki N, Kitakaze M
- Journal Title
  
  American Journal of Physiology Heart and Circulatory Physiology
  
  Volume: 304(10)
- DOI
  10.1152/ajpheart.00454.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590817, KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591097
[Journal Article] Treatment of cerebral ischemia-reperfusion injury with PEGylated liposomes encapsulating FK5062013
- Author(s)
  Ishii T, Asai T, Oyama D, Agato Y, Yasuda N, Fukuta T, Shimizu K, Minamino T, Oku N.
- Journal Title
  
  FASEB Journal.
  
  Volume: 27 Pages: 1362-1370
- DOI
  10.1096/fj.12-221325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047, KAKENHI-PROJECT-25460041
[Journal Article] Liposomal Amiodarone Augments Anti-arrhythmic Effects and Reduces Hemodynamic Adverse Effects in an Ischemia/Reperfusion Rat Model.2013
- Author(s)
  Takahama H, Shigematsu H, Asai T, Matsuzaki T, Sanada S, Fu HY, Okuda K, Yamato M, Asanuma H, Asano Y, Asakura M, Oku N, Komuro I, Kitakaze M, Minamino T.
- Journal Title
  
  Cardiovasc. Drugs Ther.
  
  Volume: 27 Pages: 125-132
- DOI
  10.1007/s10557-012-6437-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591093, KAKENHI-PROJECT-24390203, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24591097, KAKENHI-PROJECT-25460041
[Journal Article] Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin2012
- Author(s)
  Ishii T, Asai T, Oyama D, Fukuta T, Yasuda N, Shimizu K, Minamino T, Oku N
- Journal Title
  
  J Control Release
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659416
[Journal Article] Amelioration of cerebral ischemia-reperfusion injury based on liposomal drug delivery system with asialo-erythropoietin.2012
- Author(s)
  T.Ishii, T.Asai, D.Oyama, T.Fukuta, N.Yasuda, K.Shimizu, T.Minamino, N.Oku
- Journal Title
  
  J Control Release
  
  Volume: (In press) Pages: 81-7
- DOI
  10.1016/j.jconrel.2012.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J55523, KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-23249005, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer2012
- Author(s)
  K. Nishikawa, T. Asai, H. Shigematsu, K. Shimizu, H. Kato, Y. Asano, S. Takashima, E. Mekada, N. Oku, T. Minamino
- Journal Title
  
  J Control Release
  
  Volume: 160 Pages: 274-280
- DOI
  10.1016/j.jconrel.2011.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790045, KAKENHI-PROJECT-22890104, KAKENHI-PROJECT-23240126, KAKENHI-PROJECT-23659416, KAKENHI-PROJECT-24591096, KAKENHI-PROJECT-24790047
[Journal Article] H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.2012
- Author(s)
  Yoshida A, Asanuma H, Sasaki H, Sanada S, Yamazaki S, Asano Y, Shinozaki Y, Mori H, Shimouchi A, Sano M, Asakura M, Minamino T, Takashima S, Sugimachi M, Mochizuki N, Kitakaze M.
- Journal Title
  
  Cardiovasc Drugs Ther.
  
  Volume: 26 Pages: 217-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591097
[Journal Article] Development of anti-HB-EGF immunoliposomes for the treatment of breast cancer2011
- Author(s)
  Nishikawa K, Asai T, Shigematsu H, Shimizu K, Kato H, Asano Y, Takashima S, Mekada E, Oku N, Minamino T
- Journal Title
  
  J Control Release
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659416
[Journal Article] Identification of Genes related to Heart Failure Using Global Gene Expression Profiling of Human Failing Myocardium2010
- Author(s)
  Min KD, Asakura M, Liao Y, Nakamaru K, Okazaki H, Takahashi T, Fujimoto K, Ito S, Takahashi A, Asanuma H, Yamasaki S, Minamino T, Sanada S, Seguchi O, Nakano A, Ando Y, Otsuka T, Furukawa H, Isomura T, Takashima S, Mochizuki N, Kitakaze M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 393(1) Pages: 55-60
- Data Source
  KAKENHI-PROJECT-21590945
[Journal Article] Identification of genes related to heart failure using global gene expression profiling of human failing myocardium.2010
- Author(s)
  Min KD, Asakura M, Liao Y, Nakamaru K, Okazaki H, Takahashi T, Fujimoto K, Ito S, Takahashi A, Asanuma H, Yamazaki S, Minamino T, Sanada S, Seguchi O, Nakano A, Ando Y, Otsuka T, Furukawa H, Isomura T, Takashima S, Mochizuki N, Kitakaze M.
- Journal Title
  
  Biochem Biophys Res Commun. 393(1)
  
  Pages: 55-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] X-box binding protein 1 regulates brain natriuretic peptide through a novel AP1/CRE-like element in cardiomyocytes.2010
- Author(s)
  Sawada T, Minamino T, Fu HY, Asai M, Okuda K, Isomura T, Yamazaki S, Asano Y, Okada K, Tsukamoto O, Sanada S, Asanuma H, Asakura M, Takashima S, Kitakaze M, Komuro I.
- Journal Title
  
  Journal of molecular and cellular cardiology. 48(6)
  
  Pages: 1280-1289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation.2010
- Author(s)
  Nakano A, Kato H, Watanabe T, Min KD, Yamazaki S, Asano Y, Seguchi O, Higo S, Shintani Y, Asanuma H, Asakura M, Minamino T, Kaibuchi K, Mochizuki N, Kitakaze M, Takashima S.
- Journal Title
  
  Nat Cell Biol. 12(6)
  
  Pages: 583-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload.2010
- Author(s)
  Fu HY, Okada K, Liao Y, Tsukamoto O, Isomura T, Asai M, Sawada T, Okuda K, Asano Y, Sanada S, Asanuma H, Asakura M, Takashima S, Komuro I, Kitakaze M, Minamino T.
- Journal Title
  
  Circulation. 122(4)
  
  Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Isoform-specific intermolecular disulfide bond formation of heterochromatin protein 1 (HP1).2010
- Author(s)
  Higo S, Asano Y, Kato H, Yamazaki S, Nakano A, Tsukamoto O, Seguchi O, Asai M, Asakura M, Asanuma H, Sanada S, Minamino T, Komuro I, Kitakaze M, Takashima S.
- Journal Title
  
  The Journal of biological chemistry. 285(41)
  
  Pages: 31337-31347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Overexpression of ER-resident Chaperone Attenuates ardiomyocyte Death Induced by Proteasome Inhibition2009
- Author(s)
  Fu H, Minamino T, Tsukamoto O, 他8名
- Journal Title
  
  Cardiovas Res Vol.79(4)
  
  Pages: 600-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.2009
- Author(s)
  Asai M, Tsukamoto O, Minamino T, Asanuma H, Fujita M, Asano Y, Takahama H, Sasaki H, Higo S, Asakura M, Takashima S, Hori M, Kitakaze M.
- Journal Title
  
  Journal of molecular and cellular cardiology. 46(4)
  
  Pages: 452-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Inhibition of cardiac remodeling by Pravastatin is associated with amelioration of endoplasmic reticulum stress2009
- Author(s)
  Zhao H, Liao Y, Minamino T, 他8名
- Journal Title
  
  Hypertens Res Vol.31
  
  Pages: 1977-1987
- NAID
  10024827861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] PKA rapidly enhances proteasome assembly and activityin in vivo canine hearts2009
- Author(s)
  Asai M, Tsukamoto O, Minamino T, 他10名
- Journal Title
  
  J Mol Cell Cardiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Prolonged targeting of ischemic/reperfused myocardium by liposomal adenosine augments cardioprotection in rats.2009
- Author(s)
  Takahama H, Minamino T, Asanuma H, Fujita M, Asai T, Wakeno M, Sasaki H, Kikuchi H, Hashimoto K, Oku N, Asakura M, Kim J, Takashima S, Komamura K, Sugimachi M, Mochizuki N, Kitakaze M.
- Journal Title
  
  J Am Coll Cardiol. 53(8)
  
  Pages: 709-717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Metformin prevents progression of heart failure in dogs: role of AMP-activated protein kinase.2009
- Author(s)
  Sasaki H, Asanuma H, Fujita M, Takahama H, Wakeno M, Ito S, Ogai A, Asakura M, Kim J, Minamino T, Takashima S, Sanada S, Sugimachi M, Komamura K, Mochizuki N, Kitakaze M.
- Journal Title
  
  Circulation. 119(19)
  
  Pages: 2568-2577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] PKA repidly enhances assembly and Activity in vivo canine hearts2009
- Author(s)
  Asai T, Tsukamoto O, Minamino T, 他10名
- Journal Title
  
  J Mol Cell Cardiol Vol 46
  
  Pages: 452-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Prolonged Targeting of Ischemic/Reperfused Myocardium by Liposomal Adenosine Augments Cardioprotection in Rats2009
- Author(s)
  Takahama H, Minamino T, Asanuma H, Fujita M, Asai T, Wakeno M, Sasaki H, Kikuchi H, Hashimoto K, Oku N, Asakura M, Kim J, Takashima S, Komamura K, Sugimachi M, Mochizuki N, Kitakaze M
- Journal Title
  
  Journal of the American College of Cardiology 53(8)
  
  Pages: 709-717
- Data Source
  KAKENHI-PROJECT-19390220
[Journal Article] Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress.2008
- Author(s)
  Zhao H, Liao Y, Minamino T, Asano Y, Asakura M, Kim J, Asanuma H, Takashima S, Hori M, Kitakaze M.
- Journal Title
  
  Hypertens Res. 31(10)
  
  Pages: 1977-1987
- NAID
  10024827861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Atorvastatin slows the progression of cardiac remodeling in mice with pressure overload and inhibits epidermal growth factor receptor activation.2008
- Author(s)
  Liao Y, Zhao H, Ogai A, Kato H, Asakura M, Kim J, Asanuma H, Minamino T, Takashima S, Kitakaze M.
- Journal Title
  
  Hypertens Res. 31(2)
  
  Pages: 335-344
- NAID
  10024360118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Inhibition of cardiac remodeling by pravastatin is associated with amelioration of endoplasmic reticulum stress2008
- Author(s)
  Zhao H, Liao Y, Minamino T, 他7名
- Journal Title
  
  Hypertens Res 31(10)
  
  Pages: 1977-1987
- NAID
  10024827861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Identification of a novel substrate for TNFalpha-induced kinase NUAK2.2008
- Author(s)
  Yamamoto H, Takashima S, Shintani Y, Yamazaki S, Seguchi O, Nakano A, Higo S, Kato H, Liao Y, Asano Y, Minamino T, Matsumura Y, Takeda H, Kitakaze M.
- Journal Title
  
  Biochem Biophys Res Commun. 365(3)
  
  Pages: 541-547
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Identification of p32 as a novel substrate for ATM in heart.2008
- Author(s)
  Kato H, Takashima S, Asano Y, Shintani Y, Yamazaki S, Seguchi O, Yamamoto H, Nakano A, Higo S, Ogai A, Minamino T, Kitakaze M, Hori M.
- Journal Title
  
  Biochem Biophys Res Commun. 366(4)
  
  Pages: 885-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390225
[Journal Article] Overexpression of ER-resident Chaperone Attenuates Cardiomyocyte Death Induced by Proteasome Inhibition2008
- Author(s)
  Fu H, Minamino T, Tsukamoto O, 他8名
- Journal Title
  
  Cardiovas Res 79(4)
  
  Pages: 600-610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning2007
- Author(s)
  Fujita M, Asanuma H, Hirata A, Wakeno M, Takahama H, Sasaki H, Kim J, Takashima S, Tsukamoto O, Minamino T, Shinozaki Y, Tomoike H, Hori M, Kitakaze M
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology 292(4)
- Data Source
  KAKENHI-PROJECT-19390220
[Journal Article] A Novel Cardiac Myosin Light Chain Kinase Regulates Sarcomere Assembly in the Vertebrate Heart.2007
- Author(s)
  Osamu Seguchi, Seiji Takashima, Satoru Yamazaki, Masanori Asakura, Yoshihiro Asano, Yasunori Shintani, Masakatsu Wakeno, Tetsuo Minamino, Hiroya Kondo, Hidehiko Furukawa, Kenji Nakamaru, Asuka NaitoTomoko Takahashi, Toshiaki Ohtsuka, Koichi Kawakami, Tadashi Isomura, Soichiro Kitamura, Hitonobu Tomoike, Naoki Mochizuki, Masafumi Kitakaze
- Journal Title
  
  J. of Clin.Invest. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390229
[Journal Article] Prolonged transient acidosis during early reperfusion contributes to the cardioprotective effects of postconditioning.2007
- Author(s)
  Fujita M, Asanuma H, Hirata A, Wakeno M, Takahama H, Sasaki H, Kim J, Takashima S, Tsukamoto O, Minamino T, Shinozaki Y, Tomoike H, Hori M, Kitakaze M.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 292(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Increased Endoplasmic Reticulum Stress in Atheroscleroticlaques Associated With Acute Coronary Syndrome.2007
- Author(s)
  Myoishi M, Hao H, Minamino T, Watanabe K, Nishihira K, Hatakeyama K, Asada Y, Okada KI, Ishibashi-Ueda H, Gabbiani G, Bochaton-Piallat ML, Mochizuki N, Kitakaze M
- Journal Title
  
  Circulation 116
  
  Pages: 1226-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] Increased Endoplasmic Reticulum Stress in Atherosclerotic Plaques Associated With Acute Coronary Syndrome2007
- Author(s)
  Myoishi M, Hao H, Minamino T, 他10名
- Journal Title
  
  Circulation Vol.116(11)
  
  Pages: 1226-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590815
[Journal Article] S-nitrosylated and pegylated hemoglobin, a newly developed artificial oxygen carrier, exerts cardioprotection against ischemic hearts.2007
- Author(s)
  Asanuma H, Nakai K, Sanada S, Minamino T, Takashima S, Ogita H, Fujita M, Hirata A, Wakeno M, Takahama H, Kim J, Asakura M, Sakuma I, Kitabatake A, Hori M, Komamura K, Kitakaze M.
- Journal Title
  
  J Mol Cell Cardiol. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Long-term stimulation of adenosine Alb receptors begun after myocardial infarction prevents cardiac remodeling in rats.2006
- Author(s)
  Wakeno M, Minamino T, Seguchi O, Okazaki H, Tsukamoto O, Okada K, Hirata A, Fujita M, Asanuma H, Kim J, Komamura K, Takashima S, Mochizuki N, Kitakaze M.
- Journal Title
  
  Circulation. 114(18)
  
  Pages: 1923-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs2006
- Author(s)
  Hirata A, Minamino T, 他
- Journal Title
  
  J Am Coll Cardiol. 48(1)
  
  Pages: 176-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats.2006
- Author(s)
  Wakeno M, Minamino T, 他
- Journal Title
  
  Circulation 114(18)
  
  Pages: 1923-1932
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats.2006
- Author(s)
  Tsukamoto, O., Minamino, T., Sanada, S., Okada, K., Hirata, A., Fujita, M., Shintani, Y., Yulin, L., Asano, Y, Takashima, S., Yamasaki, S., Tomoike, H., Hori, M., Kitakaze, M.
- Journal Title
  
  Cardiovasc Drugs Ther 20
  
  Pages: 93-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390229
[Journal Article] Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs.2006
- Author(s)
  Hirata A, Minamino T, Asanuma H, Fujita M, Wakeno M, Myoishi M, Tsukamoto O, Okada K, Koyama H, Komamura K, Takashima S, Shinozaki Y, Mori H, Shiraga M, Kitakaze M, Hori M.
- Journal Title
  
  J Am Coll Cardiol. 48(1)
  
  Pages: 176-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats2006
- Author(s)
  Wakeno M, Minamino T, Seguchi O, Okazaki H, Tsukamoto O, Okada K, Hirata A, Fujita M, Asanuma H, Kim J, Komamura K, Takashima S, Mochizuki N, Kitakaze M
- Journal Title
  
  Circulation 114(18)
  
  Pages: 1923-1932
- Data Source
  KAKENHI-PROJECT-19390220
[Journal Article] Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition.2006
- Author(s)
  Okazaki H, Minamino T, Tsukamoto O, Kim J, Okada K, Myoishi M, Wakeno M, Takashima S, Mochizuki N, Kitakaze M.
- Journal Title
  
  Hypertens Res. 29(4)
  
  Pages: 277-84
- NAID
  10017985662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Blockade of histamine H2 receptors protects the heart against ischemia and reperfusion injury in dogs2006
- Author(s)
  Asanuma H, Minamino T, 他
- Journal Title
  
  J Mol Cell Cardiol 40(5)
  
  Pages: 666-674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Blockade of histamine H2 receptors protects the heart against ischemia and reperfusion injury in dogs.2006
- Author(s)
  Asanuma H, Minamino T, Ogai A, Kim J, Asakura M, Komamura K, Sanada S, Fujita M, Hirata A, Wakeno M, Tsukamoto O, Shinozaki Y, Myoishi M, Takashima S, Tomoike H, Kitakaze M.
- Journal Title
  
  J Mol Cell Cardiol. 40(5)
  
  Pages: 666-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Angiotensin II type 1 receptor blocker prevents atrial structural remodeling in rats with hypertension induced by chronic nitric oxide inhibition2006
- Author(s)
  Okazaki H, Minamino T, 他
- Journal Title
  
  Hypertens Res 29(4)
  
  Pages: 277-284
- NAID
  10017985662
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Journal Article] Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats.2006
- Author(s)
  Wakeno, M., Minamino, T., Seguchi, O., Okazaki, H., Tsukamoto, O., Okada, K., Hirata, A., Fujita, M., Asanuma, H., Kim, J., Komamura, K., Takashima, S., Mochizuki, N., Kitakaze, M.
- Journal Title
  
  Circulation. 114
  
  Pages: 1923-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390229
[Patent] 炎症性疾患治療用医薬組成物2014
- Inventor(s)
  南野哲男
- Industrial Property Rights Holder
  南野哲男
- Industrial Property Rights Type
  特許
- Filing Date
  2014-03-23
- Overseas
- Data Source
  KAKENHI-PROJECT-24591096
[Patent] 炎症性疾患治療用医薬組成物2012
- Inventor(s)
  南野哲男、小室一成、松崎高志、奥直人、浅井知浩、富海英
- Industrial Property Rights Holder
  国立大学法人大阪大学、静岡県効率大学法人
- Industrial Property Number
  2012-117077
- Filing Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23659416
[Patent] 心筋の小胞体ストレス抑制剤2007
- Inventor(s)
  南野哲男ら、他3名
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2007-09-25
- Data Source
  KAKENHI-PROJECT-19590815
[Patent] 心筋の小胞体ストレス抑制剤2007
- Inventor(s)
  南野哲男・他3名
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2007-247227
- Filing Date
  2007-09-25
- Data Source
  KAKENHI-PROJECT-19590815
[Patent] METHOD FOR DIAGNOSING HEART FAILURE2006
- Inventor(s)
  Tetsuo Minamino et al.
- Industrial Property Rights Holder
  Osaka University
- Filing Date
  2006-08-10
- Data Source
  KAKENHI-PROJECT-17590731
[Patent] METHOD FOR DIAGNOSING HEART FAILURE2006
- Inventor(s)
  Tetsuo, Minamino et al.
- Industrial Property Rights Holder
  Osaka University
- Filing Date
  2006-08-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590731
[Patent] 心不全の判定方法2006
- Inventor(s)
  南野哲男, 堀正二, 岡田健一郎, 北風政史
- Industrial Property Rights Holder
  国立大学法人大阪大学, 財団法人ヒューマンサイエンス振興財団
- Industrial Property Number
  2006-016514
- Filing Date
  2006-01-25
- Data Source
  KAKENHI-PROJECT-17590731
[Presentation] Late Breaking Clinical Trials 2 (HF) : Low dose Erythropoietin in Patients with ST segment Elevation Myocardial Infarction (EPO AMI II Study): A Randomized Controlled Clinical Trial2017
- Author(s)
  南野哲男
- Organizer
  第81回日本循環器学会学術集会総会
- Place of Presentation
  金沢
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04821
[Presentation] A chemical ER chaperone attenuates cardiac dysfunction by doxorubicin2016
- Author(s)
  南野哲男
- Organizer
  Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  仙台
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04821
[Presentation] A Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin- induced Cardiac Dysfunction2016
- Author(s)
  南野哲男
- Organizer
  日本循環器学会学術集会プレナリーセッション 20年後を見据えた心不全診療のあり方 ―基礎・臨床研究からの提言と臨床での実践―
- Place of Presentation
  仙台
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15H04821
[Presentation] Ablation of IL-33 gene Exacerbate Myocardial Remodeling in Mice with Heart Failure Induced by Mechanical Stress2016
- Author(s)
  Punniyakoti Veeraveedu Thanikachalam, Shoji Sanada, Tetsuo Minamino
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  宮城県仙台市・仙台国際センター
- Year and Date
  2016-03-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461108
[Presentation] シンポジウム３「先端医療とDDSの進展」ドッラクデリバリーシステムを用いた急性心筋梗塞治療薬の開発2016
- Author(s)
  南野哲男
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  岐阜
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15H04821
[Presentation] Detection of target protein via aptamer electrostatically immobilized on wireless-electrodeless QCM biosensor chip2015
- Author(s)
  鳥居宏臣、荻博次、平尾雅彦、山戸昌樹、松崎高志、南野哲男
- Organizer
  第36回超音波エレクトロニクスの基礎と応用に関するシンポジウム
- Place of Presentation
  つくば国際会議場、つくば市
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-15H03587
[Presentation] シンポジウム＜新たに見えてきた慢性心不全治療の標的　Novel treatment targets of heart failure＞ Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload2013
- Author(s)
  南野哲男
- Organizer
  第76回日本循環器学会総会・学術集会・
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24591096
[Presentation] シンポジウム2 ＜小胞体ストレスと活性酵素ストレスのクロストーク＞心血管リモデリングにおける小胞体ストレス応答の役割解明2012
- Author(s)
  南野哲男
- Organizer
  第12回日本NO学会学術集会
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-24591096
[Presentation] シンポジウム : 心不全における心筋バイオマーカー小胞体ストレス誘導分子の心不全マーカーとしての有用性2009
- Author(s)
  南野哲男
- Organizer
  第12回日本心不全学会学術大学
- Place of Presentation
  東京
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-19590815
[Presentation] Symposium 10 <SubcellRemodeling in the Failing Heart> <Ablation of C/EBP Homologous Protein Attenuates ER-mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload>2009
- Author(s)
  南野哲男
- Organizer
  第73回日本循環器学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-20
- Data Source
  KAKENHI-PROJECT-19590815
[Presentation] ミニシンポジウム<Cancer Therapeutics and Cardiotoxicity> 小胞体ケミカルシャペロンによるドキソルビシン心毒性の軽減効果2009
- Author(s)
  南野哲男
- Organizer
  第88回大阪府立成人病センターセミナーシリーズ
- Place of Presentation
  大阪
- Year and Date
  2009-03-23
- Data Source
  KAKENHI-PROJECT-19590815
[Presentation] Management of Hyperphosphatemia Is an Important Novel Therapeutic Target In Chronic Heart Failure2008
- Author(s)
  Asanuma H, Asakura M, Kim J, Takahama H, Sasaki H, Sanada S, Ohara T, Min K, Ito S, Fujita M, Asano Y, Takashima S, Minamino T, Komamura K, Kitakaze M
- Organizer
  米国心臓協会年次学術集会 2008
- Data Source
  KAKENHI-PROJECT-19390220
[Presentation] Activation of Myocardial AMP-activated Protein Kinase by Metformin Prevents Progression of Heart Failure in Dogs; Involvement of eNOS Activation2008
- Author(s)
  Sasaki H, Asanuma H, Fujita M, Takahama H, Asakura M, Kim J, Minamino T, Takashima S, Sanada S, Ito S, Min K, Komamura K, Mochizuki N, Kitakaze M
- Organizer
  米国心臓協会年次学術集会 2008
- Data Source
  KAKENHI-PROJECT-19390220
[Presentation] 冠動脈プラーク破綻の新しい指標-小胞体ストレス誘導分子の測定キット開発2008
- Author(s)
  南野哲男
- Organizer
  第56回日本心臓病学会学術集会・パネルディスカッション
- Place of Presentation
  東京
- Year and Date
  2008-09-09
- Data Source
  KAKENHI-PROJECT-19590815
[Presentation] Inhibition of Cardiac Remodeling by Pravastatin is Associated withAmelioration of Endoplasmic Reticulum Stress2008
- Author(s)
  Zhao H, Liao Y, Minamino T, Asano Y, Asakura M, Kim J, Asanuma H, Takashima S, Hori M, Kitakaze M
- Organizer
  米国心臓協会年次学術集会 2008
- Data Source
  KAKENHI-PROJECT-19390220
[Presentation] Distinct Regulation of Cardiac Function by Histone Deacetylase Inhibitors in Response to Pressure Overload2008
- Author(s)
  Me J, Minamino T, Asano Y, Liao YL, Kitakaze M, Wang SW
- Organizer
  米国心臓協会年次学術集会 2008
- Data Source
  KAKENHI-PROJECT-19390220
[Presentation] Polyethylene-glycol coated liposomal adenosine attenuates hypotension and bradycardia and augments cardioprotection against ischemia/repertusion injury in rats - Nano-size drug delivery system targeted to infarcted myocardium2007
- Author(s)
  Takahama H, Minamino T, Asanuma H, Fujita M, Wakeno M, Asakura M, Kim J, Takashima S, Komamura K, Hori M, Mochizuki N, Kitakaze M
- Organizer
  米国心臓協会年次学術集会 2007
- Data Source
  KAKENHI-PROJECT-19390220
[Presentation] Academic Drug Development for Treatment of Acute Myocardial Infarction Using Nano-sized Liposomes
- Author(s)
  南野哲男
- Organizer
  日本循環器学会学術集会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591096
[Presentation] アカデミア創薬：院内GMPリポソームを用いた急性心筋梗塞に対する新しい治療薬の開発
- Author(s)
  南野哲男
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京（慶応義塾大学薬学部芝共立キャンパス）
- Year and Date
  2015-07-30 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-24591096
[Presentation] Development of Novel Therapy for Autoimmune Myocarditis with Nanotechnology
- Author(s)
  富　海英、南野哲男
- Organizer
  日本心不全学会　YIA
- Place of Presentation
  埼玉県大宮市
- Data Source
  KAKENHI-PROJECT-24591096

1. TAKASHIMA Seiji (90379272)

# of Collaborated Projects: 9 results

# of Collaborated Products: 34 results
2. MASAFUMI Kitakaze (20294069)

# of Collaborated Projects: 6 results

# of Collaborated Products: 31 results
3. ASANO Yoshihiro (60527670)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
4. TSUKAMOTO Osamu (80589151)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
5. SANADA Shoji (70593797)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
6. HIGO Schuichiro (00604034)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. HORIO Masatsugu (20124779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
8. ASAKURA Masanori (80443505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
9. MORI Kazutoshi (70182194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. KATO Hisakazu (30589312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
11. MATSUZAKI Takashi (90456939)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. HAO Hiroyuki (40393243)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. 村上和司 (60575207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KIM Jiyoong (30393226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
15. OGAI Akiko (90359274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOMOIKE Hitonobu (90112333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. NAKATANI Satoshi (80393221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KOMAMURA Kazuo (90311448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. OYADOMARI Seiichi (90502534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HARADA Akihiro (40251441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YAMAZAKI Satoru (70348796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
22. ASANUMA Hiroshi (20416217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
23. OGITA Hisakazu (50379236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TOYOFUKU Toshihiko (60322179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKEDA Hiroshi (20127252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Ogi Hirotsugu (90252626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. 後藤祐児 (40153770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 中村暢伴 (50452404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 浅井知浩 (00381731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
30. 野間貴久 (20363202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 富海英 (70754646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 舛形尚 (70263910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 千田彰一 (30145049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 松永圭司 (70791052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. NAKANO Atsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
36. IHARA Madoka

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. MIN Kyung-Duk

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
38. Yan Yi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
39. IMAMURA Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. ITO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. SATO Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. SAKATA Yasuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. SHINDO Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. TAKAHASHI Ayako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 小室一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
47. 木岡秀隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
48. 野地博行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 鈴木俊治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 藤川誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 新谷泰範

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
52. 小倉尚志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 吉川信也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 新沢伊藤恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 砂真一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 坂田泰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. 小出裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 奥直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
59. 清水広介

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
60. 目加田英輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. 岩本亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Minamino Tetsuo 南野 哲男

南野 哲男 ミナミノ テツオ

MINAMINO Tetsuo 南野 哲男

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小学生におけるLDL-コレステロールの健診スクリーニングの意義Principal InvestigatorOngoing

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Development of a sitting position ultrasonic examination method for patient safety and its application to evaluation of cardiac function of flail patients and long-term care recipientsOngoing

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Development of antibody-drug conjugate to diagnose and treat vulnerable plaquePrincipal Investigator

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Role of ER oxidoreductin-1 in cardiovascular remodelingPrincipal Investigator

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Development of image diagnosis and treatment for fluminant myocarditisPrincipal Investigator

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Pathophysiological Role of ER-Ubiquitin/Proteasome System in Cardiovascular RemodelingPrincipal Investigator

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Minamino Tetsuo 南野哲男

南野哲男ミナミノテツオ

MINAMINO Tetsuo 南野哲男