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YOSHIDA Tadashi  吉田 匡

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… Alternative Names

吉田 匡  ヨシダ タダシ

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Researcher Number 10004673
Other IDs
External Links
Affiliation (Current) 2025: 山形大学, 医学部, その他
Affiliation (based on the past Project Information) *help 1987 – 2007: School of Med. Dept. of Molecular and Pathological Biochemistry, Professor, 医学部, 教授
1986 – 1987: 山形大学, 医学部, 助教授
1986: 山形大, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Functional biochemistry / General medical chemistry / Structural biochemistry / Functional biochemistry / 代謝生物化学
Except Principal Investigator
代謝生物化学 / Functional biochemistry / Functional biochemistry / Cell biology / General medical chemistry / Pathological medical chemistry
Keywords
Principal Investigator
CO / ヘムオキシゲナーゼ / ビリベルジン / ヘムの分解 / 酸素活性化機構 / ビリルビン / ヘム / オキシゲナーゼ / 酵素活性化機構 / 酵素活性化 … More / Hmu O / Heme oxygenase / Corynebacterium diphtheriae / ジフテリア菌 / シアノバクテリア / ベルドヘム / BILIVERDIN / OXYGEN ACTIVATION / HEME OXYGENASE / ビリベルジン還元酵素 / ピリルビン / 細菌のヘム分解酵素 / Bilirubin / ビソルビン / ヘム分解 / アイソザイム / フマラーゼ / Production of fumarase / cDNA for fumarase / Isozyme / Fumarase / フマラーゼの生成 / フマラーゼのcDNA / フマラ-ゼの生成 / フマラ-ゼのcDNA / フマラ-ゼ / Tubulin / O-methylation / Protein carboxymethyltransferase / 高分子量微小管結合蛋白質 / 高分子単微小管結合蛋白質 / チュブリン / O-メチレーション / 蛋白質カルボキシメチル化反応 / Soybean, GmHO-1 / Cyanobacterium / Biliverdin / Verdoheme / Hydroxyheme / Oxygen activation / ショウジョウバエ / 過酸化水素 / 鉄 / ピリベルジン / 大豆ヘムオキシゲナーゼ / ヒドロキシヘム / 酸素活性化 / CYANOBACTERIUM / VERDOHEME / meso-HYDROXYHEME / HYDROPEROXO SPECIES / メソヒドロキシヘム / ヒドロペルオキソ / BILIRUBIN / BILIVERDIN REDUCTASE / INTERMEDIARY STEP / HEME DEGRADATION / ピリペルジン / 中間過程 / biliverdin / Activation of oxygen / Heme degradation enzyme / Heme degradation / オキシグナーゼ / ヘムオキシグナーゼ / HmuO / Bieiverdin / Degradation of heme / Heme / O_2 activation mechanism / Oxygenase / ビリベリジン / heme pocket / Insertion mechanism to microsome / site directed mutagenesis / Expression in E. coli / heme oxygenase / ヘムポケット / 小胞体への定着機構 / 部位指定変異 / 大腸菌での発現 / ヘムオキシゲナ-ゼ / ビソベルジン / 酸素活圧化 / CO親和性 / 酸素親和性 / COS細胞での発現 / 翻訳調節 / 液胞 / 膜透過 / 前駆体蛋白質 / プラスチド / 液泡 / ペルオキシソーム / ミトコンドリア / 核 … More
Except Principal Investigator
ミトコンドリア / ヘムオキシゲナーゼ / mitochondria / ヘム分解酵素 / カドミウム / heme oxygenase / bypass-import / 細胞質因子 / バイパス輸送 / 膜透過装置 / コンタクトサイト / 輸送装置 / ミトコンドリア蛋白質前駆体 / 転写調節 / ヒートショックタンパク質 / ストレスタンパク質 / メタルレスポンシブエレメント / 遺伝子発現調節 / 総括班 / 蛋白質の選別輸送 / 蛋白質の膜透過 / Receptor for precursor protein / Cytosolic factor / Precursor of Ornithine aminotransferase / Fxtra-peptide / Mitochondria / 細胞内局在化機構 / リポソーム / オルニチンアミノ基転移酵素前駆体 / 附加ペプチド / 蛋白質細胞内局在化機構 / 前駆体受容体 / オルニナンアミノ基転移酵素前駆体 / 付加ペプチド / regulation of reactions / protein / molecular recognition / specificity of species / enzymatic reaction mechanism / 反応制御 / タンパク質 / 分子認識 / 生物種依存性 / 酵素反応機構 / mitochondrial inner membrane / mitochondrial outer membrane / protein translocation / protein targeting / プレシークエンス / ミトコンドリア内膜 / ミトコンドリア外膜 / 蛋白質膜透過 / 蛋白質のターゲッティング / porin / re-translocation / transport machinery / protein transport / 膜間腔蛋白質 / ポリン / 再輸送 / 蛋白質輸送 / degradation of heme / HSP32 / cadmium / heat shock protein / stress protein / transcriptional control / 遺伝子発現 / CATアッセイ / ストレス関連蛋白質 / ヘムオキシゲナ-ゼ / translocation machinery / contact site / import machinery / presequence / mitochondrial protein precursor / 前駆体蛋白質 / 前駆体蛋白質受容体 / 延長ペプチド / Methylation / Brain / cDNA for protein carboxyl methyltransferase / Aging / Protein carboxyl methyltransferase / 蛋白質一次構造 / 異常アスパラギン酸 / cDNA塩基配列解析 / 神経生化学 / Sーアデノシルメチオニン / 蛋白質メチル化 / 脳 / 老化 / cDNAクロ-ニング / 蛋白質カルボキシメチル基転移酵素 / 転写因子 / USF / ヘム / ストレス / 転写制御 / 蛋白質の分泌 / タンパク質輸送 / オルガネラ / ソーティング / 小胞輸送 / 膜透過 Less
  • Research Projects

    (27 results)
  • Research Products

    (1 results)
  • Co-Researchers

    (32 People)
  •  How different biological species make heme oxygenase suit their own needs?_Elucidation of the dependence of heme catabolism on species

    • Principal Investigator
      MIGITA Taiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamaguchi University
  •  Mechanism of heme degradation by heme oxygenase and diversity of heme oxygenase among the various organismsPrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  Mechanism of heme degradation by heme oxygenase and the interaction of hemePrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  Relation between the structure and the oxygen acitivation of heme oxygenase reactionPrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      YAMAGATA UNIVERSITY
  •  ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Yamagata University
  •  ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Yamagata University
  •  Mechanism of heme degradation by heme oxygenasePrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Structural biochemistry
    • Research Institution
      YAMAGATA UNIVERSITY
  •  Molecular Mechanism of Mitochondrial Protein Import and Sorting

    • Principal Investigator
      ONO Hideyu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      YAMAGATA UNIVERSITY
  •  ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yamagata University
  •  Molucular mechanisms of oxygen activation at the three steps in heme oxygenase reactionPrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      YAMAGATA UNIVERSITY
  •  ヘムオキシゲナーゼの構造と機能との関連(特に酸素活性化について)Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yamagata University
  •  重金属ストレスによる群特異的遺伝子転写調節機構の解明

    • Principal Investigator
      佐藤 道比古
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  ヘムオキシゲナーゼによるヘム分解の中間過程の解析Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  Molecular mechanism of heme degradation catalyzed by heme oxygenasePrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Structural biochemistry
    • Research Institution
      YAMAGATA UNIVERSITY
  •  ラットヘムオキシゲナーゼ遺伝子の重金属による転写調節機構

    • Principal Investigator
      SATO Michihiko
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  一つのmRNAから翻訳される二種のフマラーゼアイソザイムの生成機構Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Yamagata University
  •  核、ミトコンドリア、ペルオキシソーム蛋白質局在化の分子機構Principal Investigator

    • Principal Investigator
      吉田 匡
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yamagata University
  •  Mechanism of targeting and transport of mitochondrial precursor proteins to mitochondria

    • Principal Investigator
      ISHIKAWA Kazunobu, 斧 秀勇
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamagata University
  •  蛋白質の膜透過と選別輸送の分子機構

    • Principal Investigator
      水島 昭二
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  蛋白質の膜透過と選別輸送の分子機構

    • Principal Investigator
      多賀谷 光男, 水島 昭二
    • Project Period (FY)
      1991 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo University of Pharmacy and Life Science
      The University of Tokyo
  •  On the role of heme oxygenase as a oxygen radical scavenger

    • Principal Investigator
      SATO Michihiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Yamagata University
  •  Molecular mechanism of recognition of mitochondrial protein precursor by mitochondria

    • Principal Investigator
      ONO Hideyu, 坪井 昭三
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Yamagata University
  •  Relation between structure and function of heme oxygenase and its insertion mechanism to microsomal membranesPrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Yamagata University
  •  On the Protein Carboxyl Methylation of the Aged Protein in the Brain

    • Principal Investigator
      SATO Michihiko
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      代謝生物化学
    • Research Institution
      Yamagata University
  •  Mechanism of the production of two isozymes of fumarase encoded from a single genePrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamagata University
  •  Research on the receptor for the precursors of mitochondrial proteins and the cytosolic factor required for their import

    • Principal Investigator
      TUBOI Syozo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Yamagata University School of Medicine, Department of Biochemistry
  •  Protein carboxymethyltransferase and its physiological significancePrincipal Investigator

    • Principal Investigator
      YOSHIDA Tadashi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Yamagata University

All 2006

All Journal Article

  • [Journal Article] Migita2006

    • Author(s)
      Tomohiko, Gohya, Xuhong, Zhang, Tadashi, Yoshida, Catharina, T
    • Journal Title

      the FEBS Journal 273

      Pages: 5384-5399

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570130
  • 1.  SATO Michihiko (00135344)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  FUJII Hiroshi (80228957)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  ONO Hideyu (40160915)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  MIGITA Taiko (90159161)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  ZHANG Zuhong (10292442)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  ISHIKAWA Kazunobu (80222959)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TUBOI Syozo (70004554)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  水島 昭二 (50013313)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  大村 恒雄 (80029933)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  多賀谷 光男 (30179569)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  IUCHI Yoshihito (60272069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MIGITA Kouto (90116757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  田代 裕 (40077558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  加藤 敬太郎 (70037571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  米田 悦啓 (80191667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  橋本 隆 (80009935)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  長谷 俊治 (00127276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  伊藤 明夫 (30037379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  森 正敬 (40009650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  中野 明彦 (90142140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  徳田 元 (40125943)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  勝沼 信彦 (50035375)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  鈴木 民夫 (30206502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  野口 正人 (10124611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OLSON John S.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  IKEDA-SAITO Masao
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  周 虹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  ZHOU Hong
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  兪 善昌
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ROUSSEAU Den
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  IKEDAーSAITO マサオ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  OLSOH John S
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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