Kurose Hitoshi 黒瀬等

… Alternative Names

黒瀬等クロセヒトシ

KUROSE Hitoshi 黒瀬等

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Researcher Number	10183039
Other IDs	https://orcid.org/0000-0003-4257-702X
External Links
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(薬学域), 徳島大学専門研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 徳島大学, 大学院医歯薬学研究部(薬学域), 徳島大学専門研究員 2016 – 2020: 九州大学, 薬学研究院, 教授 2011 – 2015: 九州大学, 薬学研究科(研究院), 教授 2012: 九州大学, 薬学研究院, 教授 2010: Kyushu University, 大学院・薬学研究院・薬効安全性学, 教授 … More 2010: 九州大学, 薬学研究院, 教授 2008 – 2009: Kyushu University, 大学院・薬学研究院, 教授 2006 – 2007: 九州大学, 薬学研究院, 教授 2005 – 2006: 九州大学, 大学院薬学研究院, 教授 2002 – 2004: Kyushu University, Pharmacology and Toxicology, Professor, 大学院・薬学研究院, 教授 2001: 東京大学, 大学院・薬学研究科, 助教授 1999 – 2001: 東京大学, 大学院・薬学系研究科, 助教授 1999: 東京大学, 大学院・薬学研究科, 助教授 1997 – 1998: The University of Tokyo, Graduate School of Pharmaceutical Sciences, Laboratory, 大学院・薬学系研究科, 助手 1994 – 1996: 東京大学, 薬学部, 助手 1987: 東京大学, 薬学部, 教務職員 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related / 医薬分子機能学 / Biological Sciences / Biological Sciences Except Principal Investigator Biological pharmacy / 医薬分子機能学 / 代謝生物化学
Keywords	Principal Investigator Gタンパク質 / 受容体キナーゼ / 炎症 / 心筋梗塞 / 貪食 / 細胞内シグナリング / 活性酸素 / NFAT / アンジオテンシン受容体 / TRPCチャネル … More / 受容体 / 線維化 / cAMP依存性リン酸化酵素 / G12ファミリー / TGF-β / angiotensin receptor / G protein / reactive oxygen species / 酸化ストレス / (-)-RO-363 / 細胞外微小環境 / 免疫学 / 循環器・高血圧 / シグナル伝達 / 薬理学 / 免疫細胞 / Gタンパク質共役型受容体キナーゼ / アポトーシス / シグナリング / MAPキナーゼ / 心肥大応答 / 細胞内Ca^<2+>濃度 / ホスホリパーゼC / アデノシン-三リン酸 / 心機能 / cGMP依存性リン酸化酵素 / ホスホジエステラーゼ5阻害剤 / リン酸化 / 圧負荷 / 心肥大 / G蛋白質 / β1アドレナリン受容体 / 百日咳毒素 / プロテインキナーゼC / がん化 / 脂質 / プロトン感知性受容体 / バイアス型阻害作用 / 阻害薬 / Gタンパク質選択的受容体 / 内皮細胞 / connective tissue growth factor / TRPC channels / intracellular Ca^2+ / G proteins / cardiac fibrosis / cardiac hypertrophy / G_<12>タンパク質 / G_qタンパク質 / 心筋線維化応答 / 結合組織成長因子 / 心臓の線維化 / hypertrophy / fibrosis / heart / MAP kinase / システイン修飾 / 肥大 / 心臓 / intracellular mediator / signaling molecule / cysteine residue / oxidative stress / セリン変異体 / 細胞保護 / 酸素毒性 / 細胞内メディエーター / シグナリング分子 / システイン / structure of ligand / constitutively active receptor / selective agonist / transmembrane region / β1-adrenergic receptor / 三次元モデル / β_1アドレナリン受容体 / アラニン置換型受容体 / リガンドの構造 / 構成的活性化受容体 / 選択的アゴニスト / 細胞膜貫通領域 / GFP / BRETプローブ / NF-κB経路 / TNF-α / 心疾患 / 線維芽細胞 / 抗炎症作用 / 死細胞 / 筋線維芽細胞 / 好中球 / ロイコトリエンB4受容体 / 拮抗薬 / ロイコトリエン受容体 / 白脾髄 / 赤脾臓 / 赤血球のリサイクル / ERMファミリー / マクロファージ / 自己免疫疾患 / 細胞内シグナル伝達 / G タンパク質共役型受容体キナーゼ / 圧負荷モデル / 化合物Pyr3 / 選択的阻害剤 / 細胞内Ca^<2+>制御 / 圧負荷ストレス / cGMP依存性タンパク質リン酸化酵素 / ホスホジエステラーゼ阻害剤 / cGMP / BRET / β_2アドレナリン受容体 / クラスリンボックス / G protein-coupled receptor kinase 2 / スカホールド蛋白質 / エンドサイトーシス / クラスリン / 低分子量G蛋白質 / 新生仔心室筋細胞 / ジアシルグリセロール / 13蛋白質 / G_12 / Rho / 伸展刺激 / G_q蛋白質 / 線維化促進因子 / パネキシン / プリン受容体 / アンジオテンシンII受容体 / ATP / 心不全 / キナーゼ / AUF-1 / RNA-タンパク質相互作用 / 3'-非翻訳領域 / mRNA / α_2-アドレナリン受容体 / コレラ毒素 / モノクロナール抗体 / アンチセンスDNA / α_2アドレナリン受容体 / 脱感作 / B_1-アドレナリン受容体 … More Except Principal Investigator 百日咳毒素 / βアドレナリン受容体 / 受容体キナーゼ / ERK / JNK / L-type Ca^<2+> channel / 心肥大 / 興奮収縮連関 / 心不全 / 情報伝達 / GTP結合蛋白質 / 2-ハイブリッド法 / cardiac hypertrophy / cardiac myocyte / C^<2+> channel / Ca^<2+> signaling / seven transmembrane / G protein / oxidative stress / reactive oxygen species / リアノジン受容体 / カルシウムチャネル / カルシウムシグナリング / システイン / G-タンパク質 / 心筋細胞 / Ca^<2+>チャネル / Ca^<2+>シグナル / 7回膜貫通型受容体 / Gタンパク質 / 酸化ストレス / 活性酸素 / heart failure / endothelin / catecholamine / β-adrenergic receptor / 細胞内シグナル伝達 / p38MAPK / エンドセリン / L型カルシウムチャネル / カテコラミン / Myocardial infarction model / β adrenergic receptors / Ca^<2+> handling / Ca^<2+> transients / Cardiac muscle / Excitation-contraction coupling / Heart failure / 過分極活性型(If)チャネル / カルシウムトランジェント / 洞房結節 / 細胞骨格 / カルシウムチャネル / カルシウムシグナリング / 梗塞モデル / 心筋梗塞モデル / Ca^<2+>ハンドリング / L型Ca^<2+>チャネル / Ca^<2+>トランジェント / 心筋 / G protein-coupled receptors / desensitization / adonovirus / subtype specificily / G protein-coupled receptor kinase / single chain Fv molecule / monoclonal antibody / intracellular immunization / 抗体遺伝子 / モノクロール抗体 / 調節機構 / 細胞内発現 / 細胞特異性 / 抗体分子の遺伝子 / Gタンパク質共役型受容体 / 脱感作 / アデノウイルス / サブタイプ特異性 / Gタンパク質共役型受容体キナーゼ / 一本鎖抗体 / モノクローナル抗体 / 細胞内免疫 / ユビキチン / ts変異株 / DNA複製開始 / 増殖制御機構 / 突然変異株 / ポリオーマウイルス / DNA合成 / 情報伝達系 / 細胞増殖 / 正常細胞 / 変異株 / IAP / 増殖制御 / Blue Fluerescent Protein(BFP) / Green Fluerescent Protein(GFP) / Green Fluorescent Protein(GFP) / CLCP Cl^-チャネル / 細胞内局在 / 蛍光共鳴エネルギー転移 / タンパク質-タンパク質相互作用 / HEK293細胞 / Cl^-チャネル / βアレスチン / インターナリゼーション Less

G12ファミリーのGタンパク質を介したシグナルの解析Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  The University of Tokushima
Analysis of the roles and interaction of various cells including myofibroblasts involved in fibrosis after myocardial infarctionPrincipal Investigator
- Principal Investigator
  
  KUROSE HITOSHI
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
心筋梗塞におけるロイコトリエンB4受容体の役割解析Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Roles of extracellular environment and various cells carrying different function for cardiac fibrosisPrincipal Investigator
- Principal Investigator
  
  KUROSE HITOSHI
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
Attempt of G protein-coupled receptor kinase-interacting proteins involved in engulfment of apoptotic cells and role of the receptor kinase in heart diseasePrincipal Investigator
- Principal Investigator
  
  KUROSE HITOSHI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyushu University
Role of GRK in engulfment of apoptotic cellsPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
Roles of Voltage- and cation-independent TRPC channels in cardiac hypertrophyPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
クラスリンのエンドサイトーシスとは関係しない細胞内シグナリング経路への役割解析Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
The mechanism of G protein-mediated cardiac fibrosisPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
mechanistic analysis of cardiac functions by building G protein signal networkPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Establishment of a role of reactive oxygen species as a second messengerPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
mRNA結合タンパク質の機能を阻害するペプチドの創製と細胞現象への適用Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
Novel Therapeutic Strategy for Heart Failure : Molecular Mechanism underlying the Regulation of Ca^<2+> Signaling in the Heart
- Principal Investigator
  
  NAGAO Taku
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
Redox Regulation of Signal Transduction Mechanism in the HeartPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
  The University of Tokyo
Role of receptor kinase in β1-adrenergic receptor signaling, and hypertrophy/heart failure
- Principal Investigator
  
  NAGAO Taku
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  University of Tokyo
Structural analysis and molecular modeling of high affinity binding and activation of β1-adrenergic receptorPrincipal Investigator
- Principal Investigator
  
  KUROSE Hitoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  University of Tokyo
Study on regulatory mechanism for cardiac contraction : seeking for therapeutic basis of heart failure.
- Principal Investigator
  
  NAGAO Taku
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Tokyo
βアドレナリン受容体の機能の解析とその制御メカニズム
- Principal Investigator
  
  長尾拓
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
蛍光共鳴エネルギー転移FRETを用いた2つのタンパク質の相互作用の測定
- Principal Investigator
  
  長尾拓
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
α_2-アドレナリン受容体のプロテインキナーゼCによる調節機構Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
α_2-アドレナリン受容体の調節機構Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
Establishment of Functional Analysis by Expressing Antibody Molecule in the Cells
- Principal Investigator
  
  NAGAO Taku
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo (Granduate School of Pharm.Sci.)
B_1-アドレナリン受容体の調節機構Principal Investigator
- Principal Investigator
  
  黒瀬等
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
正常およびがん化細胞の増殖におけるGTP結合蛋白質の役割
- Principal Investigator
  
  宇井理生
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
細胞増殖を支配する情報伝達系ーGTP結合蛋白質の関与を中心にー
- Principal Investigator
  
  宇井理生
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
突然変異株を用いた哺乳類細胞増殖制御機構の研究
- Principal Investigator
  
  花岡文雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo

[Book] 標準薬理学　第８版2021
- Author(s)
  黒瀬　等
- Publisher
  医学書院
- ISBN
  9784260041638
- Data Source
  KAKENHI-PROJECT-17H01525
[Book] バイアス型シグナル2016
- Author(s)
  黒瀬等
- Total Pages
  6
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25253011
[Book] βアドレナリン受容体2016
- Author(s)
  黒瀬等
- Total Pages
  7
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] New Therapeutics for Heart Failure: Focusing on cGMP Signaling.2023
- Author(s)
  Mangmool S, Duangrat R, Parichatikanond W, Kurose H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24 Issue: 16 Pages: 12866-12866
- DOI
  10.3390/ijms241612866
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06646
[Journal Article] Biased Signaling through G Protein-coupled Receptors2022
- Author(s)
  Kurose H.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 10 Pages: 1091-1101
- DOI
  10.1248/yakushi.22-00087
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-10-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06646
[Journal Article] Cardiac fibroblasts and fibrosis2022
- Author(s)
  Kurose H.
- Journal Title
  
  生化学
  
  Volume: 94 Issue: 1 Pages: 49-66
- DOI
  10.14952/SEIKAGAKU.2022.940049
- ISSN
  0037-1017
- Year and Date
  2022-02-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06646
[Journal Article] Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression2022
- Author(s)
  Nishiyama Kazuhiro、Nishimura Akiyuki、Shimoda Kakeru、Tanaka Tomohiro、Kato Yuri、Shibata Takahiro、Tanaka Hiroshi、Kurose Hitoshi、Azuma Yasu-Taka、Ihara Hideshi、Kumagai Yoshito、Akaike Takaaki、Eaton Philip、Uchida Koji、Nishida Motohiro
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 716 Pages: 716-716
- DOI
  10.1126/scisignal.abj0644
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07085, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-20K16008, KAKENHI-PLANNED-21H05263, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19J20086, KAKENHI-PROJECT-22K06646, KAKENHI-ORGANIZER-21H05258, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-22H00356
[Journal Article] A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.2022
- Author(s)
  Shimauchi T, Numaga-Tomita T, Kato Y, Morimoto H, Sakata K, Matsukane R, Nishimura A, Nishiyama K, Shibuta A, Horiuchi Y, Kurose H, Kim SG, Urano Y, Ohshima T, Nishida M.
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 13 Pages: 2041-2041
- DOI
  10.3390/cells11132041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06646, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05208, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H02607, KAKENHI-PROJECT-19K07116, KAKENHI-PROJECT-23K24035
[Journal Article] Pharmacology of Antagonism of GPCR2022
- Author(s)
  Kurose H, Kim SG.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 6 Pages: 669-674
- DOI
  10.1248/bpb.b22-00143
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-06-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06646
[Journal Article] Efferocytosis during myocardial infarction.2020
- Author(s)
  Yoshimura C, Nagasaka A, Kurose H, Nakaya M.
- Journal Title
  
  J Biochem.
  
  Volume: 68 Issue: 1 Pages: 1-6
- DOI
  10.1093/jb/mvaa051
- NAID
  40022279056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-20H03383
[Journal Article] Drebrin is induced during myofibroblast differentiation and enhances the production of fibrosis-related genes.2020
- Author(s)
  Hironaka T, Ueno T, Mae K, Yoshimura C, Morinaga T, Horii Y, Nagasaka A, Kurose H, Nakaya M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 529 Issue: 2 Pages: 224-230
- DOI
  10.1016/j.bbrc.2020.05.110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083
[Journal Article] Leukotriene B4 receptor 1 exacerbates inflammation following myocardial infarction.2020
- Author(s)
  Horii Y, Nakaya M, Ohara H, Nishihara H, Watari K, Nagasaka A, Nakaya T, Sugiura Y, Okuno T, Koga T, Tanaka A, Yokomizo T, Kurose H.
- Journal Title
  
  FASEB Journal
  
  Volume: 印刷中 Issue: 6 Pages: 8749-8763
- DOI
  10.1096/fj.202000041r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-19K07122, KAKENHI-PROJECT-19K07357, KAKENHI-PROJECT-20K07328, KAKENHI-PROJECT-19KK0199, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-18H02627, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-19J20083
[Journal Article] Therapeutic Targets for the Treatment of Cardiac Fibrosis and Cancer: Focusing on TGF-β Signaling2020
- Author(s)
  Parichatikanond W, Luangmonkong T, Mangmool S, Kurose H.
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 7 Pages: 34-34
- DOI
  10.3389/fcvm.2020.00034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Journal Article] Gα12/13 signaling in metabolic diseases.2020
- Author(s)
  Yang YM, Kuen DS, Chung Y, Kurose H, Kim SG.
- Journal Title
  
  Exp Mol Med
  
  Volume: 52 Issue: 6 Pages: 896-910
- DOI
  10.1038/s12276-020-0454-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Journal Article] The roles of inhibitory Smads in cancer progression2019
- Author(s)
  Hironaka T, Ohba Y, Kurose H, Nakaya M.
- Journal Title
  
  Nihon Yakurigaku Zasshi
  
  Volume: 154 Pages: 44-44
- NAID
  130007678393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01525
[Journal Article] Therapeutic Targets for Treatment of Heart Failure: Focus on GRKs and β-Arrestins Affecting βAR Signaling.2018
- Author(s)
  Mangmool S, Parichatikanond W, Kurose H.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 9 Pages: 1336-1336
- DOI
  10.3389/fphar.2018.01336
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Journal Article] Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance2018
- Author(s)
  Koshimizu TA, et al.
- Journal Title
  
  Nat Neurosci
  
  Volume: Epub ahead of print Issue: 6 Pages: 820-833
- DOI
  10.1038/s41593-018-0144-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04323, KAKENHI-PROJECT-15K15055, KAKENHI-PROJECT-18K19404, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-17H03984
[Journal Article] Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.2018
- Author(s)
  Kim TH, Yang YM, Han CY, Koo JH, Oh H, Kim SS, You BH, Choi YH, Park TS, Lee CH, Kurose H, Noureddin M, Seki E, Wan YY, Choi CS, Kim SG.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 12 Pages: 5587-5602
- DOI
  10.1172/jci97831
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Journal Article] Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.2017
- Author(s)
  Michio Nakaya,Kenji Watari,Mitsuru Tajima,Takeo Nakaya,Shoichi Matsuda,Hiroki Ohara,Hiroaki Nishihara,Hiroshi Yamaguchi,Akiko Hashimoto,Mitsuho Nishida,Akiomi Nagasaka,Yuma Horii,Hiroki Ono,Gentaro Iribe,Ryuji Inoue,Makoto Tsuda,Kazuhide Inoue,Akira Tanaka,Masahiko Kuroda,Shigekazu Nagata,Hitoshi Kurose
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 127 Issue: 1 Pages: 383-401
- DOI
  10.1172/jci83822
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01383, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-16J03451, KAKENHI-PROJECT-26293088, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15100, KAKENHI-PROJECT-16K08718, KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04678
[Journal Article] Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration2017
- Author(s)
  Takeda Tomoki、Komiya Yukiko、Koga Takayuki、Ishida Takumi、Ishii Yuji、Kikuta Yasushi、Nakaya Michio、Kurose Hitoshi、Yokomizo Takehiko、Shimizu Takao、Uchi Hiroshi、Furue Masutaka、Yamada Hideyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 25 Pages: 10586-10599
- DOI
  10.1074/jbc.m116.764332
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04708, KAKENHI-PROJECT-17H03984
[Journal Article] β-Adrenergic Receptor and Insulin Resistance in the Heart.2017
- Author(s)
  Mangmool S, Denkaew T, Parichatikanond W, Kurose H.
- Journal Title
  
  Biomol Ther (Seoul).
  
  Volume: 25 Issue: 1 Pages: 44-56
- DOI
  10.4062/biomolther.2016.128
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-17H01525
[Journal Article] The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction.2017
- Author(s)
  Nagasaka A, Mogi C, Ono H, Nishi T, Horii Y, Ohba Y, Sato K, Nakaya M, Okajima F, Kurose H.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 7812-7812
- DOI
  10.1038/s41598-017-07573-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09856, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-15H04641, KAKENHI-PROJECT-17H03984, KAKENHI-PROJECT-16J04161, KAKENHI-PROJECT-15K06767
[Journal Article] Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction2016
- Author(s)
  Hayato Fukuda, Saki Ito, Kenji Watari, Chihiro Mogi, Mitsuhiro Arisawa, Fumikazu Okajima, Hitoshi Kurose, Satoshi Shuto
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 7 Issue: 5 Pages: 493-497
- DOI
  10.1021/acsmedchemlett.6b00014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0063, KAKENHI-PROJECT-15K14976, KAKENHI-PROJECT-15H02495, KAKENHI-PROJECT-13J03105, KAKENHI-PROJECT-26288051, KAKENHI-PUBLICLY-16H01026, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-15H04641, KAKENHI-PROJECT-16K15136
[Journal Article] The purinergic P2Y6 receptor heterodimerizes with the angiotensin AT1 receptor to promote angiotensin II-induced hypertension2016
- Author(s)
  A. Nishimura, C. Sunggip, H. Tozaki-Saitoh, T. Shimauchi, T. Numaga-Tomita, K. Hirano, T. Ide, J-M. Boeynaems, H. Kurose, M. Tsuda, B. Robaye, K. Inoue and M. Nishida
- Journal Title
  
  Science Signaling
  
  Volume: Jan 19;9(411) Issue: 411
- DOI
  10.1126/scisignal.aac9187
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18883, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-26670144, KAKENHI-PLANNED-25117013, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-25253011
[Journal Article] Myofibroblasts and inflammatory cells as players of cardiac fibrosis.2016
- Author(s)
  Kurose H, Mangmool S.
- Journal Title
  
  Arch Pharm Res.
  
  Volume: 39 Issue: 8 Pages: 1100-1113
- DOI
  10.1007/s12272-016-0809-6
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] A new approach of indirect enzyme-linked immunosorbent assay for determination of D-glutamic acid through in situ conjugation2016
- Author(s)
  Sakamoto, S., Nagamitsu, R., Matsuura, Y., Tsuneura, Y., Kurose, H., Tanaka, H.*, Morimoto, S.
- Journal Title
  
  Journal of Immunoassay and Immunochemistry
  
  Volume: 37 Issue: 3 Pages: 296-306
- DOI
  10.1080/15321819.2015.1135161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25750167, KAKENHI-PROJECT-25253011
[Journal Article] GRK6 phosphorylates IκBα at Ser32/Ser36 and enhances TNF-α-induced inflammation2015
- Author(s)
  Yuki Ohba, Michio Nakaya*, Kenji Watari, Akiomi Nagasaka, & Hitoshi Kurose.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 461 Issue: 2 Pages: 307-313
- DOI
  10.1016/j.bbrc.2015.04.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-26860056, KAKENHI-PUBLICLY-15H01383, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-13J03105, KAKENHI-PROJECT-25713007
[Journal Article] GRK6 phosphorylates IκBα at Ser32/Ser36 and enhances TNF-α-induced inflammation via the activation of NF-κB signaling.2015
- Author(s)
  Ohba Y, Nakaya M, Watari K, Nagasaka A, Kurose H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670040
[Journal Article] Identification of a new molecule that promotes clearance of apoptotic cells — G protein-coupled receptor kinase 6 is involved in engulfment of apoptotic cells2015
- Author(s)
  仲矢道雄、黒瀬等
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 145 Issue: 1 Pages: 14-20
- DOI
  10.1254/fpj.145.14
- NAID
  130004827709
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670120, KAKENHI-PROJECT-25713007, KAKENHI-PROJECT-25253011
[Journal Article] Discovery and cardioprotective effects of the first non-Peptide agonists of the g protein-coupled prokineticin receptor-1.2015
- Author(s)
  Gasser A, Brogi S, Urayama K, Nishi T, Kurose H, Tafi A, Ribeiro N, Désaubry L, Nebigil CG.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 4 Pages: e0121027-e0121027
- DOI
  10.1371/journal.pone.0121027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] Multiple functions of G protein-coupled receptor kinases2014
- Author(s)
  Watari K, Nakaya M, Kurose H
- Journal Title
  
  Journal of Molecular Signaling
  
  Volume: 9 Pages: 1-1
- DOI
  10.1186/1750-2187-9-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J03105, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-25253011, KAKENHI-PROJECT-25670120, KAKENHI-PROJECT-25713007
[Journal Article] A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells.2013
- Author(s)
  Masubuchi Y, Nakagawa Y, Ma J, Sasaki T, Kitamura T, Yamamoto Y, Kurose H, Kojima I, Shibata H.
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] Attenuated desensitization of -adrenergic receptor by water-soluble N-nitrosamines that induce S-nitrosylation without nitric oxide release.2013
- Author(s)
  Makita N, Kabasawa Y, Otani Y, Firman F, Sato J, Hashimoto M, Nakaya M, Nishihara H, Nangaku M, Kurose H, Ohwada T and Iiri T.
- Journal Title
  
  Circ. Res.
  
  Volume: 112 Pages: 327-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance2013
- Author(s)
  Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, Nishihara H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto M, Tsuda M, Kuroda M, Inoue K, Kurose H
- Journal Title
  
  Nature Commun
  
  Volume: 4 Issue: 1 Pages: 1532-1532
- DOI
  10.1038/ncomms2540
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117013, KAKENHI-PROJECT-22590083, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23659042, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25293018, KAKENHI-PROJECT-25670031, KAKENHI-PLANNED-22136008, KAKENHI-PUBLICLY-23118520, KAKENHI-PUBLICLY-24113717
[Journal Article] GRK6-deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance.2013
- Author(s)
  Nakaya M, Tajima M, Kosako H, Nakaya N, Hashimoto A, Watari K, Nishihara H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto M, Tsuda M, Kuroda M, Inoue K, Kurose H.
- Journal Title
  
  Nat. Commun.
  
  Volume: 4 Pages: 1532-1532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670040
[Journal Article] -arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarction.2013
- Author(s)
  Watari K, Nakaya M, Nishida M, Kim K-M, Kurose H.
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25116716
[Journal Article] Attenuated desensitization of b-adrenergic receptor by water-soluble N-nitrosamines that induce S-nitrosylation without NO release2013
- Author(s)
  Noriko Makita*, Yoji Kabasawa*, Yuko Otani, Firman, Junichiro Sato, Makiko Hashimoto, Michio Nakaya, Hiroaki Nishihara, Masaomi Nangaku, Hitoshi Kurose, Tomohiko Ohwada, Taroh Iiri
- Journal Title
  
  Circ. Res
  
  Volume: 112 Issue: 2 Pages: 327-334
- DOI
  10.1161/circresaha.112.277665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590083, KAKENHI-PROJECT-22591008, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23790006
[Journal Article] Increased ubiquitination and the crosstalk of G protein signaling in cardiac myocytes: involvement of Ric-8B in Gs suppression by Gq signal.2013
- Author(s)
  Jenie RI, Nishimura M, Fujino M, Nakaya M, Mizuno N, Tago K, Kurose H, Itoh H.
- Journal Title
  
  Genes Cells
  
  Volume: 18 Pages: 1095-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] Ezrin, radixin and moesin phosphorylation in NIH3T3 cells revealed angiotensin II type 1 receptor cell type-dependent biased signaling.2013
- Author(s)
  Ibrahim I.A.A.E-H. , Nakaya M, Kurose H.
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 122 Pages: 1-9
- NAID
  10031177874
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25116716
[Journal Article] Multiple signaling routes involved in the regulation of adenylyl cyclase and extracellular regulated kinase by dopamine D(2) and D(3) receptors.2013
- Author(s)
  Jin M, Min C, Zheng M, Cho DI, Cheong SJ, Kurose H, Kim KM.
- Journal Title
  
  Pharmacol. Res.
  
  Volume: 67 Pages: 31-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25253011
[Journal Article] Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration.2012
- Author(s)
  Nishida M., et al
- Journal Title
  
  Nature Chen. Biol.
  
  Volume: 8 Issue: 8 Pages: 714-724
- DOI
  10.1038/nchembio.1018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05497, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21248016, KAKENHI-PROJECT-22500337, KAKENHI-PROJECT-23651239, KAKENHI-PROJECT-23659043, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24658122, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117013, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117703
[Journal Article] beta-arrestin-mediated signaling improves the efficacy of therapeutics.2012
- Author(s)
  Ibrahim IA, Kurose H.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 118 Pages: 408-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659043
[Journal Article] Induction of cardiac fibrosis by b-blocker in G protein-independent but GRK5/b-arrestin2-dependent signaling pathways2012
- Author(s)
  Michio Nakaya, Satsuki Chikura, Kenji Watari, Natsumi Mizuno, Koji Mochinaga, Supachoke Mangmool, Satoru Koyanagi, Shigehiro Ohdo, Yoji Sato, Tomomi Ide, Motohiro Nishida & Hitoshi Kurose
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 42 Pages: 35669-35677
- DOI
  10.1074/jbc.m112.357871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590083, KAKENHI-PROJECT-23659043, KAKENHI-PLANNED-22136008
[Journal Article] Cilostazol Suppresses Angiotensin II-Induced Vasoconstriction via Protein Kinase A-mediated Phosphorylation of the Transient Receptor Potential Canonical 6 Channel.2011
- Author(s)
  Nishioka K, Nishida N, Ariyoshi M, Jian Z, Saiki S, Hirano M, Nakaya M, Sato Y, Kita S, Iwamoto T, Hirano K, Inoue R, Kurose H.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol.
  
  Volume: 31(10) Pages: 2278-2286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659043
[Journal Article] Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.2010
- Author(s)
  Nishida, M., Suda, R., Nagamatsu, Y., Tanabe, S., Onohara, N., Nakaya, M., Kanaho, Y., Shibata, T., Uchida, K., Sumimoto, H., Sato, Y., Kurose, H.
- Journal Title
  
  J Biol Chem. 285(20)
  
  Pages: 15268-15277
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Divergent roles of prokineticin receptors in the endothelial cells : angiogenesis and fenestration.2010
- Author(s)
  Guilini C, Urayama K, Turkeri G, Dedeoglu DB, Kurose H, Messaddeq N, Nebigil CG.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition.2010
- Author(s)
  Nishida M, Watanabe K, Sato Y, Nakaya M, Kitajima N, Ide T, Inoue R, Kurose H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 13244-13253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition2010
- Author(s)
  Nishida, M., Watanabe, K., Sato, Y., Nakaya, M., Kitajima, N., Ide, T., Inoue, R., Kurose, H.
- Journal Title
  
  J Biol Chem. 286(17)
  
  Pages: 13244-13253
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells.2010
- Author(s)
  Kimura T, Tomura H, Sato K, Ito M, Matsuoka I, Im DS, Kuwabara A, Mogi C, Itoh H, Kurose H, Murakami M, Okajima F.
- Journal Title
  
  J Biol Chem. 285
  
  Pages: 4387-4397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Pertussis toxin up-regulates angiotensin type 1 receptors through Toll-like receptor 4-mediated Rac activation.2010
- Author(s)
  Nishida M, Suda R, Nagamatsu Y, Tanabe S, Onohara N, Nakaya M, Kanaho Y, Shibata T, Uchida K, Sumimoto H, Sato Y, Kurose H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 15268-15277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] inhibition of TRPC6 channel actvitiy contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.2010
- Author(s)
  Kinoshita H, Kuwahara K, Nishida M, Jiang Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K.
- Journal Title
  
  Circ Res. 106(12)
  
  Pages: 1849-1860
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Phosphorylation of TRPC6 channels at Thr69 is required for anti-hypertrophic effects of phosphodiesterase 5 inhibition.2010
- Author(s)
  Nishida M, Watanabe K, Sato Y, Nakaya M, Kitajima N, Ide T, Inoue R, Kurose H.
- Journal Title
  
  J Biol Chem. 286(17)
  
  Pages: 13244-13253
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Agonist-induced endocytosis and receptor phosphorylation mediate resensitization of dopamine D_2 receptors.2010
- Author(s)
  Cho D, Zheng M, Min C, Ma L, Kurose H, Park JH, Kim KM.
- Journal Title
  
  Mol Endocrinol. 24
  
  Pages: 574-586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Inhibition of TRPC6 channel actvitiy contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart.2010
- Author(s)
  Kinoshita H, Kuwahara K, Nishida M, Jiang Z, Rong X, Kiyonaka S, Kuwabara Y, Kurose H, Inoue R, Mori Y, Nakagawa Y, Usami S, Fujiwara M, Yamada Y, Minami T, Ueshima K, Nakao K.
- Journal Title
  
  Circulation Research
  
  Volume: 106 Pages: 1849-1860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.2009
- Author(s)
  Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T, Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi. T., Sato, Y., Sato, C, Hamachi, I., Mori, Y.
- Journal Title
  
  Proceedings of the National Academy of Sciences of the USA 106巻
  
  Pages: 5400-5405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.2009
- Author(s)
  Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi. T., Sato, Y., Sato, C., Hamachi, I., Mori, Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 5400-5405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites.2009
- Author(s)
  Komachi M, Tomura H, Malchinkhuu E, Tobo M, Mogi C, Yamada T, Kimura T, Kuwabara A, Ohta H, Im DS, Kurose H, Takeyoshi I, Sato K, Okajima F.
- Journal Title
  
  Carcinogenesis 30
  
  Pages: 457-465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound.2009
- Author(s)
  Kiyonaka, S., Kato, K., Nishida, M., Mio, K., Numaga, T., Sawaguchi, Y., Yoshida, T., Wakamori, M., Mori, E., Numata, T., Ishii, M., Takemoto, H., Ojida, A., Watanabe, K., Uemura, A., Kurose, H., Morii, T., Kobayashi. T., Sato, Y., Sato, C., Hamachi, I., Mori, Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106(13)
  
  Pages: 5400-5405
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] Amphotericin B-induced renal tubular cell injury is mediated by Na^+ Influx through ion-permeable pores and subsequent activation of mitogen-activated protein kinases and elevation of intracellular Ca^<2+> concentration.2009
- Author(s)
  Yano T, Itoh Y, Kawamura E, Maeda A, Egashira N, Nishida M, Kurose H, Oishi R.
- Journal Title
  
  Antimicrob.Agents Chemother. 53
  
  Pages: 1420-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] 機械的伸展刺激により活性化されるGタンパク質共役型受容体の解析2008
- Author(s)
  西田基宏、上村綾、仲矢道雄、黒瀬等
- Journal Title
  
  表面 46
  
  Pages: 28-38
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Prokineticin Receptor-1 Induces Neovascularization and Epicardial-Deri ved Progenitor Cell Differentiation2008
- Author(s)
  Urayama, K., Celia Guilini, C., Turkeri, G., Takir, S., Kurose, H., Messaddeq, N., Dierich, A., and Nebigil, C.G.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology 28
  
  Pages: 841-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Keapl regulates the constitutive expression of GST Al during differentiation of Caco-2 cells.2008
- Author(s)
  Kusano, Y, Horie, S., Shibata, T, Satsu, H., Shimizu, M, Hitomi, E., Nishida, M., Kurose, H., Itoh, K., Kobayashi, A., Yamamoto, M., Uchida, K.
- Journal Title
  
  Biochemistry 47
  
  Pages: 6169-6177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced.2008
- Author(s)
  Obara, Y, Okano, Y, Ono, S., Yamauchi, A., Hoshino, T., Kurose, H., Nakahata, N.
- Journal Title
  
  Cellular Signaling 20
  
  Pages: 1275-1283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390025
[Journal Article] P2Y_6 receptor-Ga_(12/13) signaling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis2008
- Author(s)
  Nishida, M., Sato, Y., Uemura, A., Narita, Y., Tozaki-Saitoh, H., Nakay a, M., Ide, T., Suzuki, K., Inoue, K., Nagao, T., and Kurose, H.
- Journal Title
  
  EMBO Journal 27
  
  Pages: 3104-3115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] P2Y6 receptor-Gα12/13 signaling in cardiomyocytes triggers pressure overload-induced cardiac fibrosis2008
- Author(s)
  Nishida, M., Sato, Y., Uemura, A., Narita, Y., Tozaki-Saitoh, H., Nakaya, M., Ide, T., Suzuki, K., Inoue, K., Nagao, T., Kurose, H.
- Journal Title
  
  EMBO J. 27(23)
  
  Pages: 3104-3115
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor2007
- Author(s)
  Cho, E.Y., Cho, D.L, Park, J.H., Kurose, H., Caron, M.C, Kim, K.M.
- Journal Title
  
  Molecular Endcrinology 21
  
  Pages: 2242-2254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Gα_<12/13>-mediated upregulation of TRRC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through NFAT activation.2007
- Author(s)
  Nishida, M.・Onohara, N.・Sato, Y.・Suda, R・Ogushi, M.・Tanabe, S.・Inoue, R.・Mori, Y.・Kurose, H.
- Journal Title
  
  Journal of Biological Chemiostry 282
  
  Pages: 23117-23128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Small GTPase Rho signaling is involved in β1 integrin- mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor KB ligand on osteoblasts and osteoclast maturation2007
- Author(s)
  Hirai, F., Nakayamada, S., Okada, Y., Saito, K., Kurose, H., Mogami, A., Tanaka, Y
- Journal Title
  
  Biochemical Biophysical Research Communications 356
  
  Pages: 279-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Gα12/13-mediated upregulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through NFAT activation2007
- Author(s)
  Nishida, M., Onohara, N., Sato, Y., Suda, R., Ogushi, M., Tanabe, S., Inoue, R., Mori, Y., Kurose, H
- Journal Title
  
  Journal of Biological Chemistry 282
  
  Pages: 23117-23128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] TRPチャネルと心疾患2007
- Author(s)
  黒瀬等、西田基宏
- Journal Title
  
  生化学 79
  
  Pages: 953-956
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] The prokineticin receptor-1(GPR73) promotes cardiomyocyte survival and angiogenesis.2007
- Author(s)
  Urayama, K.・Guilini, C.・Messaddeq, N.・Hu, K.・Steenman, M.・Kurose, H.・Ert, G.・Nebigil, C.G.
- Journal Title
  
  FASEB Journal 21
  
  Pages: 2980-2993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] イオンチャネルと心疾患-心肥大形成とTRPC-NFATシグナリング2007
- Author(s)
  黒瀬等、西田基宏
- Journal Title
  
  医学のあゆみ 223
  
  Pages: 464-468
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Small GTPase Rho signaling is involved in β1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor κB lig and on osteoblasts and osteoclast maturation.2007
- Author(s)
  Hirai, F., Nakayamada, S., Okada, Y.Saito, K., Kurose, H., Mogami, A., and Tanaka, Y.
- Journal Title
  
  Biochemical and Biophysical Research Communications 356
  
  Pages: 279-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] イオンチャネルと心疾患-心肥大形成とTRPC-NFATシグナリング-2007
- Author(s)
  黒瀬等、西田基宏
- Journal Title
  
  医学のあゆみ 223
  
  Pages: 464-468
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanism2007
- Author(s)
  Tobo, M., Tomura, H., Mogi, C. Wang, ,JQ, Liu, JP., Komachi, M., Damirin, A., Kimura, T., Murata, N., Kurose, H., Sato, K., Okajima, F
- Journal Title
  
  Cellular Signalling 19
  
  Pages: 1745-1753
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Small GTPase Rho signaling is involved in (β1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor KB lig and on osteoblasts and osteoclast maturation2007
- Author(s)
  Hirai, F., Nakayamada, S., Okada, Y.Saito, K., Kurose, H., Mogami, A., and Tanaka, Y
- Journal Title
  
  Biochemical and Biophysical Research Communications 356
  
  Pages: 275-285
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Gα12/13-mediated upregulation of TRPC6 negatively regulates endothelin-1-induced cardiac myofibroblast formation and collagen synthesis through NFAT activation2007
- Author(s)
  Nishida, M., Onohara, N., Sato, Y., Suda, R., Ogushi, M., Tanabe, S., Inoue, R., Mori, Y., Kurose, H.
- Journal Title
  
  J. Biol. Chem. 282(32)
  
  Pages: 23117-23128
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] The prokineticin receptor-1 (GPR73) promotes cardiomyocyte survival and angiogenesis2007
- Author(s)
  Urayama, K., Guilini, C., Messaddeq, N., Hu, K., Steenman, M., Kurose, H., Ert, G., Nebigil, CG
- Journal Title
  
  FASEB Journal 21
  
  Pages: 2980-2993
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Previously postulated 'ligand-independent'signaling of GPR4 is mediated through proton-sensing mechanism2007
- Author(s)
  Tobo, M., Tomura, H., Mogi, C., Wang, J.Q., Liu, J.P., Komachi, M., Damirin, A., Kimura, T., Murata, N., kurose, H., Sato, K., and Okajima, F
- Journal Title
  
  Cellular Signalling 19
  
  Pages: 1745-1753
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] アンジオテンシン受容体2007
- Author(s)
  黒瀬等
- Journal Title
  
  日薬理誌 130
  
  Pages: 232-234
- NAID
  10025739876
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Previously postulated 'ligand-independent' signaling of GPR4 is mediated through proton-sensing mechanism.2007
- Author(s)
  Tobo, M., Tomura, H., Mogi, C., Wang, J.Q., Liu, J.P., Komachi, M., Damirin, A., Kimura, T., Murata, N., Kurose, H., Sato, K., and Okajima, F.
- Journal Title
  
  Cellular Signalling 19
  
  Pages: 1745-1753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Roles of protein kinase C and actin-binding protein 280 in the regulation of intracellular trafficking of dopamine D3 receptor2007
- Author(s)
  Cho, EY, Cho, DI, Park, JH, Kurose, H., Caron, MG, Kim, KM
- Journal Title
  
  Molecular Endocrinology 21
  
  Pages: 2242-2254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Heterotrimeric G protein Gα13-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts.2006
- Author(s)
  Nagamatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., Kurose, H.
- Journal Title
  
  J. Pharmacol. Sci. 101
  
  Pages: 144-150
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells.2006
- Author(s)
  Kimura, T., Tomura, H., Mogi, C., Kuwabara, A., Ishiwara, M., Shibasawa, K., Sato, K., Ohwada, S., Im, D.S, Kurose, H., Ishizuka, T., Murakami, M., Okajima, F.
- Journal Title
  
  Cellular Signalling 18(6)
  
  Pages: 841-850
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Thromboxane A_2 receptor-mediated G_<12/13>-dependent glial morphological change2006
- Author(s)
  Honma, S., Saika, M., Ohkubo, S., Kurose, H., Nakahata, N
- Journal Title
  
  European Journal of Pharmacology 545
  
  Pages: 100-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.2006
- Author(s)
  Onohara, N., Nishida, N., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H.
- Journal Title
  
  EMBO Journal 25(22)
  
  Pages: 5305-5316
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Thromboxane A_2 receptor-mediated G_<12/13>-dependent glial morphological change.2006
- Author(s)
  Honma, S., Saika, M., Ohkubo, S., Kurose, H., Nakahata, N.
- Journal Title
  
  European Journal of Pharmacology 545 (2-3)
  
  Pages: 100-108
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Heterotrimeric G protein Gα13- induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts2006
- Author(s)
  Nagamatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., Kurose, H
- Journal Title
  
  Journal of Pharmacological Sciences 101
  
  Pages: 144-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Clathrin required for phosphorylation and internalization of β_2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).2006
- Author(s)
  Mangmool, S., Haga, T., Kobayashi, H., Kim, K-M., Nakata, H., Nishida, M., Kurose, H.
- Journal Title
  
  Journal of Biological Chemistry 281(42)
  
  Pages: 31940-31949
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Heterotrimeric G protein Gα_13-induced induction of cytokine mRNAs through two distinct oathwavs in cardiac fibroblasts.2006
- Author(s)
  Naganatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., Kurose, H.
- Journal Title
  
  Journal of Pharmacological Sciences 101
  
  Pages: 144-150
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Beta-blockers shows inverse agonism to a novel constitutively active mutant of β_1-adrenoceptor.2006
- Author(s)
  Ahmed, M., Muntasir, H.A., Hossain, M., Isiguro, M., Komiyama, T., Muramatsu, I., Kurose, H., Nagatomo, T.
- Journal Title
  
  Journal of Pharmacological Sciences 102
  
  Pages: 167-172
- NAID
  10020345451
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Clathrin required for phosphorylation and internalization of β_2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).2006
- Author(s)
  Mangmool, S., Haga, T., Kobayashi, H., Kim, K-M., Nakata, H., Nishida, M., Kurose, H.
- Journal Title
  
  Journal of Biological Chemistry 281 (42)
  
  Pages: 31940-31949
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy2006
- Author(s)
  Onohara, N., Nishida, N., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H
- Journal Title
  
  EMBO Journal 25
  
  Pages: 5305-5316
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Beta-blockers shows inverse agonism to a novel constitutively active mutant of β1-adrenoceptor2006
- Author(s)
  Ahmed, M., Muntasir, H.A., Hossain, M., Isiguro, M., Komiyama, T., Muramatsu, I., Kurose, H., Nagatomo, T.
- Journal Title
  
  Journal of Pharmacological Sciences 102
  
  Pages: 167-172
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Heterotrimeric G protein Gα_<13>-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts.2006
- Author(s)
  Naganatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., Kurose, H.
- Journal Title
  
  Journal of Pharmacological Sciences 101
  
  Pages: 144-150
- NAID
  10018237777
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells.2006
- Author(s)
  Kimura, T., Tomura, H., Mogl, C., Kuwabara, A., Ishiwara, M., Shibasawa, K., Sato, K., Ohwada, S., Im, D.S, Kurose, H., Ishizuka, T., Murakami, M., Okajima, F.
- Journal Title
  
  Cellular Signalling 18 (6)
  
  Pages: 841-850
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Thromboxane A_2 receptor-mediated G_<12/13>-dependent glial morphological change.2006
- Author(s)
  Honma, S., Saika, M., Ohkubo, S., Kurose, H., Nakahata, N.
- Journal Title
  
  European Journal of Pharmacology 545(2-3)
  
  Pages: 100-108
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Clathrin required for phosphorylation and internalization of β2-adrenergic receptor by G protein-coupled receptor kinase (GRK2).2006
- Author(s)
  Mangmool, S., Haga, T., Kobayashi, H., Kim, K.-M., Nakata, H., Nishida, M., Kurose, H
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 31940-31949
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells.2006
- Author(s)
  Kimura, T., Tomura, H., Mogi, C., Kuwabara, A., Ishiwara, M., Shibasawa, K., Sato, K., Ohwada, S., Im, D.S, Kurose, H., Ishizuka, T., Murakami, M., Okajima, F.
- Journal Title
  
  Cellular Signalling 18(6)
  
  Pages: 841-850
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells2006
- Author(s)
  Kimura, T., Tomura, H., Mogi, C., Kuwabara, A., Ishiwara, M., Shibasawa, K., Sato, K., Ohwada, S., Im, DS, Kurose, H., Ishizuka, T., Murakami, M., Okajima, F
- Journal Title
  
  Cellular Signalling 18
  
  Pages: 841-850
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.2006
- Author(s)
  Onohara, N., Nishida, N., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H.
- Journal Title
  
  EMBO Journal 25 (22)
  
  Pages: 5305-5316
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.2006
- Author(s)
  Onohara, N., Nishida, N., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H.
- Journal Title
  
  EMBO J. 25(22)
  
  Pages: 5305-5316
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Heterotrimeric G protein Gα_<13>-induced induction of cytokine mRNAs through two distinct pathways in cardiac fibroblasts.2006
- Author(s)
  Naganatsu, Y., Nishida, M., Onohara, N., Fukutomi, M., Maruyama, Y., Kobayashi, H., Sato, Y., Kurose, H.
- Journal Title
  
  Journal of Pharmacological Sciences 101
  
  Pages: 144-150
- NAID
  10018237777
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.2006
- Author(s)
  Onohara, N., Nishida, N., Inoue, R., Kobahasyi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H.
- Journal Title
  
  EMBO Journal 25(22)
  
  Pages: 5305-5316
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Thromboxane A_2 receptor-mediated G_<12/13>-dependent glial morphological change.2006
- Author(s)
  Honma, S., Saika, M., Ohkubo, S., Kurose, H., Nakahata, N.
- Journal Title
  
  European Journal of Pharmacology 545(2-3)
  
  Pages: 100-108
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Clathrin required for phosphorylation and internalization of β_2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2).2006
- Author(s)
  Mangmool, S., Haga, T., Kobayashi, H., Kim, K-M., Nakata, H., Nishida, M., Kurose, H.
- Journal Title
  
  Journal of Biological Chemistry 281(42)
  
  Pages: 31940-31949
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Beta-blockers shows inverse agonism to a novel constitutively active mutant of β_1-adrenoceptor.2006
- Author(s)
  Ahmed, M., Muntasir, H.A., Hossain, M., Isiguro, M., Komiyama, T., Muramatsu, I., Kurose, H., Nagatomo, T.
- Journal Title
  
  Journal of Pharmacological Sciences 102
  
  Pages: 167-172
- NAID
  10020345451
- Data Source
  KAKENHI-PROJECT-18659024
[Journal Article] Beta-blockers shows inverse agonism to a novel constitutively active mutant of β_1-adrenoceptor.2006
- Author(s)
  Ahmed, M., Muntasir, H.A., Hossain, M., Isiguro, M., Komiyama, T., Muramatsu, I., Kurose, H., Nagatomo, T.
- Journal Title
  
  Journal of Pharmacological Sciences 102
  
  Pages: 167-172
- NAID
  10020345451
- Data Source
  KAKENHI-PROJECT-18390028
[Journal Article] Caveolae-independent activation of protein kinase A in rat neonatal myocytes.2005
- Author(s)
  Fukutomi, M., Nishida, M., Maruyama, Y., Kobayashi, H., Kurose, H.
- Journal Title
  
  Journal of Pharmacological Science 98(2)
  
  Pages: 168-174
- NAID
  10025728483
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Caveolae-independent activation of protein kinase A in rat neonatal myocytes.2005
- Author(s)
  Fukutomi, M., Nishida, M., Maruyama, Y., Kobayashi, H., Kurose, H.
- Journal Title
  
  J. Pharmacol. Sci. 98(2)
  
  Pages: 168-174
- NAID
  10025728483
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Gα_<12/13>-mediated production of reactive oxygen species is critical for angotensin receptor-induced NFAT activation in cardiac fibroblasts.2005
- Author(s)
  Fujii, T., Onohara, N., Maruyama, Y., Tanabe, S., Kobayashi, H., Fukutomi, M., Nagamatsu, Y., Nishihara, N., Inoue, R., Sumimoto, H., Shibasaki, F., Nagao, T., Nishida, M., Kurose, H.
- Journal Title
  
  Journal of Biological Chemistry 280(24)
  
  Pages: 23041-23047
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] G_<α12/13>- and reactive oxygen species-dependent activation of c-Jun NH_2-terminal kinase and p38 mitogen -activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.2005
- Author(s)
  Nishida, M., Tanabe, S., Maruyma, Y., Mangmool, S., Urayama, K., Nagamatsu, Y., Takagahara, S., Turner, J.H., Kozasa, T., Kobayashi, H., Sato, Y., Kawanishi, T., Inoue, R., Nagao, T., Kurose, H.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 18434-18441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Journal Article] Down-regulation of Na^+/Ca^<2+> exchanger by fluvastatin in rat cardiomyoblast H9c2 cells : Involvement of RhoB in Na^+/Ca^<2+> exchanger mRNA stability.2005
- Author(s)
  Maeda, S., Matsuoka, I., Iwamoto, T., Kurose, H., Kimura, J.
- Journal Title
  
  Molecular Pharmacology 68(2)
  
  Pages: 414-420
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] G protein-coupled receptor signaling through Gq and JNK negatively regulates neural progenitor cell migration.2005
- Author(s)
  Mizuno, N., Kokubu, H., Sato, M., Nishimura, A., Yamauchi, J., Kurose, H., Itoh, H.
- Journal Title
  
  Proceedings of National Academy of Sciences USA 102(35)
  
  Pages: 12365-12370
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Gα12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 MAPK by angiotensin receptor stimulation in rat neonatal cardiomyocytes.2005
- Author(s)
  Nishida, M., Tanabe, S., Maruyama, Y., Mangmool S., Urayama K., Nagamatsu, Y., Takagahara, S., Turner, J.H., Kozasa, T., Kobayashi, H., Sato, Y., Kawanishi, T., Inoue, R., Nagao, T., Kurose, H.
- Journal Title
  
  J. Biol. Chem. 280(18)
  
  Pages: 18434-18441
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Gα_<12/13>- and reactive species-dependent activation of c-Jun NH_2-terminal kinase and p38 MAPK by angiotensin receptor stimulation in rat neonatal cardiomyocytes.2005
- Author(s)
  Nishida, M., Tanabe, S., Maruyama, Y., Mangmool S., Urayama K., Nagamatsu, Y., Takagahara, S., Turner J.H., Kozasa, T., Kobayashi, H., Sato, Y., Kawanishi, T., Inoue, R., Nagao, T., Kurose, H.
- Journal Title
  
  Journal of Biological Chemistry 280(18)
  
  Pages: 18434-18441
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Gα12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts2005
- Author(s)
  Fujii, T., Onohara, N., Maruyama, Y., Tanabe, S., Kobayashi, H., Fukutomi, M., Nagamatsu, Y., Nishihara, N., Inoue, R., Sumimoto, H., Shibasaki, F., Nagao, T., Nishida, M., Kurose, H.
- Journal Title
  
  J. Biol. Chem. 280(24)
  
  Pages: 23041-23047
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] β-Arrestin2 enhances β_2-adrenergic receptor-mediated nuclear translocation of ERK.2005
- Author(s)
  Kobayashi, H., Narita, Y., Nishida, M., Kurose, H.
- Journal Title
  
  Cell.Signal. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Journal Article] Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts.2005
- Author(s)
  Nakayamada, S., Kurose, H., Saito, K., Mogami, A., Tanaka, Y.
- Journal Title
  
  Arth.Reas.Ther. 7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Journal Article] Thronboxane A_2 promotes interleukin-6 synthesis mediated by an activation of cyclic AMP-response element binding prptein in 1321N1 human astrocytome cells.2005
- Author(s)
  Obara, Y., Kurose, H., Nakahata, N.
- Journal Title
  
  Molecular Pharmacology 68(3)
  
  Pages: 670-679
- Data Source
  KAKENHI-PROJECT-17079007
[Journal Article] Involvement of ERK MAP kinase in endoplasmic reticulum stress in SH-SY5Y human neuroblastoma cells.2004
- Author(s)
  Arai, K., Lee, S-R., van Leyen, K., Kurose, H., Lo, E.H.
- Journal Title
  
  J.Neurochem. 89
  
  Pages: 232-239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Journal Article] TDAG8 is a proteon-sensing and psychosine-sensitive G-protein-coupled receptor.2004
- Author(s)
  Wang, J-Q., Kon, J., Magi, C., Tobo, M., Damirin, A., Sato, K., Komachi, M., Malchinkhuu, E., Murata, N., Kimura, T., Kuwabara, A., Wakamatsu, K., Koizumi, H., Uede, T., Tsujimoto, G., Kurose, H., Sato, T., Harada, A., Misawa, N., Tonomura, H., Okajima, F.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 45626-45633
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Journal Article] Properties of rat melanin-concentrating receptor 1 internalization.2004
- Author(s)
  Saito, Y., Tetsuka, M., Li, Y., Kurose, H., Maruyama, K.
- Journal Title
  
  Peptide 25
  
  Pages: 1597-1604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390027
[Presentation] β-Blocker Signaling in Cardiac Myocytes.2021
- Author(s)
  Hitoshi Kurose
- Organizer
  第85回日本循環器学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] G protein selectivity of antagonists.2020
- Author(s)
  Hitoshi Kurose
- Organizer
  NIPS International Meeting on Cardiovascular Physiology 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] プロトン感知性GPCR（GPR4）に着目した心筋梗塞時におけるpH低下の生理的影響の解析2019
- Author(s)
  荻野瑠星、伊藤峻太、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Smad6を安定化し、BMPシグナルを抑制するユビキチンリガーゼの同定2019
- Author(s)
  廣中貴則、大場悠生、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2019
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Smad6を安定化させ、BMPシグナルを抑制するユビキチンリガーゼの同定2019
- Author(s)
  廣中貴則、大場悠生、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞後の応答におけるGタンパク質共役型受容体の役割2019
- Author(s)
  黒瀬　等
- Organizer
  第48回日本心脈管作動物質学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Smad6の安定化を介してBMPシグナルを抑制するubiquitin ligaseの同定2018
- Author(s)
  大場悠生、仲矢道雄、廣中貴則、小迫英尊、長坂明臣、黒瀬等
- Organizer
  第17回次世代を担う若手ファーマ・バイオフォーラム2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Construction of Gα13-selective designer GPCR2018
- Author(s)
  Masaki Hagiwara, Akiomi Nagasaka, Michio Nakaya, Hitoshi Kurose
- Organizer
  Translational Research Metabolic and Inflammatory Diseases and Cancer, Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1 deteriorates inflammation following myocardial infarction2018
- Author(s)
  Yuma Horii, Michio Nakaya, Hiroaki Nishihara, Hiroki Ohara, Kenji Watari, Akiomi Nagasaka, Hitoshi Kurose
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (IUPHAR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心疾患のシグナリング解析2018
- Author(s)
  黒瀬等
- Organizer
  第30回蔵王カンファランス
- Invited
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Role of proton-sensing GPCR (GPR4) in myocardial infarction2018
- Author(s)
  Shunta Ito, Masaki Hagiwara, Kenji Watari, Toshihide Nishi, Akiomi Nagasaka, Michio Nakaya, Hitoshi Kurose
- Organizer
  Translational Research Metabolic and Inflammatory Diseases and Cancer, Seoul
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2018
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時の死細胞除去のメカニズム2018
- Author(s)
  黒瀬　等
- Organizer
  第5回 iHFフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞時におけるプロトン感知性GPCR（GPR4）の役割解析2018
- Author(s)
  伊藤竣太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  生体機能と創薬シンポジウム　2018
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] pH imaging at infarct area in myocardial infarction2017
- Author(s)
  萩原柾、長坂明臣、伊藤峻太、仲矢道雄、浅沼大祐、廣瀬謙造、黒瀬等
- Organizer
  69th Korean Society of Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  酸素生物学・ダイイングコード合同若手会議
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心肥大時に生じる死細胞はMFG-E8を介して貪食除去される2017
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市仙台国際センター、東北大学川内北キャンパス
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞後に出現する筋線維芽細胞の起源2017
- Author(s)
  黒瀬等、仲矢道雄、渡健治
- Organizer
  第16回生命科学研究会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] BLT1は心筋梗塞時における炎症を悪化させる2017
- Author(s)
  堀井雄真、仲矢道雄、西原弘朗、大原広貴、渡健治、長坂明臣、黒瀬等
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール、長崎新聞文化ホール　アストピア
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時におけるプロトン感知性受容体（GPR4）の役割解析2017
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] The role of GPR4 in myocardial infarction2017
- Author(s)
  伊藤峻太、萩原柾、渡健治、長坂明臣、仲矢道雄、黒瀬等
- Organizer
  69th Korean Society of Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] GRK2は、Smad6を介してBMPによる骨芽細胞の分化を促進する2017
- Author(s)
  大場悠生、仲矢道雄、小迫英尊、長坂明臣、黒瀬等
- Organizer
  第16回次世代を担う若手ファーマ・バイオフォーラム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] Cardiac Fibrosis2017
- Author(s)
  黒瀬等
- Organizer
  69th Korean Society of Pharmacology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] 心筋梗塞におけるpH低下のin vivoイメージング2017
- Author(s)
  萩原柾、長坂明臣、伊藤峻太、仲矢道雄、浅沼大祐、廣瀬謙造、黒瀬等
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17H01525
[Presentation] The role of GRK2 in BMP signaling2017
- Author(s)
  Yuki Ohba, Michio Nakaya, Akiomi Nagasaka, Hitoshi Kurose
- Organizer
  International Students' Science Camp of Kyushu University KAIST-Kyushu University Joint Seminar
- Place of Presentation
  Shikanoshima, Fukuoka
- Year and Date
  2017-01-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時の死細胞を除去するメカニズム2016
- Author(s)
  仲矢道雄、渡健治、黒瀬等
- Organizer
  第15回生命科学研究会
- Place of Presentation
  メルパルク東京
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心肥大時に生じる死細胞はMFG-E8を介して除去される2016
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  第15回　次世代を担う若手ファーマ・バイオフォーラム2016
- Place of Presentation
  大阪大学吹田地区薬学キャンパス
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時にGタンパク質共役型受容体によって仲介される応答2016
- Author(s)
  黒瀬等
- Organizer
  第８９回　日本薬理学会年会
- Place of Presentation
  横浜パシフィコ（神奈川）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞におけるpH感知性GPCR（TDAG8）の役割解析2015
- Author(s)
  西俊英、長坂明臣、小野達貴、仲矢道雄、黒瀬等
- Organizer
  第14回生命科学研究会
- Place of Presentation
  三浦市民ホール（三浦市三崎、神奈川）
- Year and Date
  2015-06-27
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 1型アンジオテンシンII受容体拮抗薬は異なるβ-アレスチン2の構造変化をおよびβ-アレスチン2-受容体相互作用を引き起こす2014
- Author(s)
  Islam IBRAHIM、仲矢道雄、黒瀬等
- Organizer
  日本薬学会　第134年会
- Place of Presentation
  熊本大学黒髪キャンパス
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] 心肥大時に生じるアポトーシス細胞はMFG-E8を介して除去される2014
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール、福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] アポトーシス細胞の貪食におけるGRK6の関与2014
- Author(s)
  仲矢道雄、黒瀬等
- Organizer
  第87回　日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-25670040
[Presentation] 心筋梗塞時におけるロイコトリエンB4受容体の役割解明2014
- Author(s)
  西原弘朗、仲矢道雄、渡健治、黒瀬等
- Organizer
  第87回　日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] 心筋梗塞時に生じる炎症応答における線維芽細胞の役割2014
- Author(s)
  黒瀬等、仲矢道雄
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学　郡元キャンパス
- Invited
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] G タンパク質共役型受容体の G タンパク質依存性と非依存性の細胞応答(シンポジウム 55「心臓・循環生理の新たな調節機構-三量体G 蛋白質シグナルの新コンセプト-」)2013
- Author(s)
  黒瀬等
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] β-アレスチン2による心筋梗塞後の炎症応答抑制メカニズムの解明2013
- Author(s)
  渡健治、仲矢道雄、西田基宏、黒瀬等
- Organizer
  第12回　生命科学研究会
- Place of Presentation
  浅虫観光ホテル
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] β-アレスチン2による心筋梗塞後の炎症応答抑制メカニズムの解明2013
- Author(s)
  渡健治、仲矢道雄、黒瀬等
- Organizer
  第66回　日本薬理学会西南部会
- Place of Presentation
  福岡大学薬学部
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] G タンパク質共役型受容体の活性を調節する分子群の疾患での役割シンポジウム2S-04「G蛋白質共役型受容体(GPCR)およびGPCRキナーゼの機能不全によって引き起こされる疾患」2012
- Author(s)
  黒瀬等、仲矢道雄
- Organizer
  第85回資本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] アポトーシス細胞の貪食におけるGRK6の役割2012
- Author(s)
  橋本明子、仲矢道雄、田島充、大場三奈、西田基宏、黒瀬等
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学高等推進機構
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] アポトーシス細胞の貪食におけるGRK6の関与2011
- Author(s)
  田島充、仲矢道雄、大場三奈、橋本明子、西田基宏、黒瀬等
- Organizer
  第10回ファーマバイオフォーラム
- Place of Presentation
  東北大学片平キャンパス　さくらホール
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] βアドレナリン受容体遮断薬によるGRK5/βアレスチン2を介した心臓の線維化2010
- Author(s)
  仲矢道雄、西田基宏、黒瀬等
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  シンポジウム
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] βアドレナリン受容体遮断薬のGRK5/βアレスチン2を介した心臓の線維化2010
- Author(s)
  仲矢道雄、西田基宏、黒瀬等
- Organizer
  日本薬学会第130年会
- Place of Presentation
  シンポジウム
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 心臓の線維化2010
- Author(s)
  黒瀬等
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  シンポジウム
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 心臓の線維化2010
- Author(s)
  黒瀬等
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 心臓の線維化2009
- Author(s)
  黒瀬等
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  九州大学病院キャンパスコラボステーション
- Year and Date
  2009-05-16
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] 線維化とプリン受容体2009
- Author(s)
  黒瀬等
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場・京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] 転写因子のシステイン修飾による受容体発現の調節機構2009
- Author(s)
  黒瀬等、西田基宏、大串真理、須田玲子、仲矢道雄
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 線維化とプリン受容体2009
- Author(s)
  黒瀬等
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] 線維化とプリン受容体2009
- Author(s)
  黒瀬等
- Organizer
  日本薬学会第129年会
- Place of Presentation
  シンポジウム
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] アンジオテンシン受容体の調節機構2008
- Author(s)
  黒瀬等、西田基宏、仲矢道雄、須田玲子、大串真理子
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜パシフィコ・横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] 抗血小板薬シロスタゾールのTRPCチャネルの抑制を介した血管拡張作用2008
- Author(s)
  有吉麻里奈、西岡絹恵、仲矢道雄、西田基宏、黒瀬等
- Organizer
  薬理学会共催・第2回トランスポーター研究会ポスター発表
- Place of Presentation
  ワークショップin福岡
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 受容体・TRPCチャネル機能連関による心肥大シグナル制御2008
- Author(s)
  西田基宏, 仲矢道雄, 黒瀬等
- Organizer
  薬理学会共催・トランスポーター研究会
- Place of Presentation
  福岡大学
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 心臓の線維化におけるG_<12/13>蛋白質の役割2008
- Author(s)
  黒瀬等、西田基宏
- Organizer
  薬理学会共催・第2回トランスポーター研究会
- Place of Presentation
  シンポジウムワークショップin福岡
- Data Source
  KAKENHI-PROJECT-20390025
[Presentation] 心臓の線維化のトリガーとなるG_<12/13>蛋白質共役型受容体の同定2007
- Author(s)
  西田基弘、黒瀬等
- Organizer
  第6回生命科学研究会
- Place of Presentation
  京成ホテルミラマーレ、千葉
- Year and Date
  2007-07-06
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] βアドレナリン受容体遮断薬の薬理2007
- Author(s)
  黒瀬等
- Organizer
  第2回臨床薬理学会/薬理学会共催シンポジウム
- Place of Presentation
  栃木県総合文化センター(宇都宮)
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-18659024
[Presentation] Roles of TRPC channel in the heart2007
- Author(s)
  黒瀬等
- Organizer
  The 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Place of Presentation
  静岡コンベンションセンター
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] βアドレナリン受容体遮断薬の薬理2007
- Author(s)
  黒瀬等
- Organizer
  第2回臨床薬理学会/薬理学会共催シンポジウム
- Place of Presentation
  栃木県総合文化センター・宇都宮
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] G_α<13>-TRPC6-NFAT signaling pathway negatively regulates cardiac myofibroblast formation2007
- Author(s)
  Nishida, M., Onohara, N., Kurose, H.
- Organizer
  G_α<13>-TRPC6-NFAT signaling pathway negatively regulates cardiac myofibroblast formation
- Place of Presentation
  Belogna, Italy
- Year and Date
  2007-06-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] 受容体発現を制御するGタンパク質2007
- Author(s)
  黒瀬等
- Organizer
  薬学会第127年会
- Place of Presentation
  富山国際会議場など・富山
- Year and Date
  2007-03-29
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] Roles of TRPCchannel in the heart2007
- Author(s)
  黒瀬等
- Organizer
  The 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Place of Presentation
  静岡コンベンションセンター
- Year and Date
  2007-05-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] リガンドに依存したシグナリングの差異2006
- Author(s)
  黒瀬等
- Organizer
  第126回薬学会年会
- Place of Presentation
  仙台国際センター・仙台
- Year and Date
  2006-03-29
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] Racを介したアンジオテンシン受容体の発現調節2006
- Author(s)
  黒瀬等
- Organizer
  第34回薬物活性シンポジウム・第115回日本薬理学会関東部会
- Place of Presentation
  高崎シティギャラリー、高崎市庁舎会議室・群馬
- Year and Date
  2006-09-29
- Data Source
  KAKENHI-PROJECT-17079007
[Presentation] GRK6 and heart disease
- Author(s)
  Hitoshi Kurose
- Organizer
  FASEB Science Research Conference ~G protein-coupled receptor kinases
- Place of Presentation
  Steamboat Spring, Colorado, USA
- Year and Date
  2014-06-09 – 2014-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-25670040
[Presentation] ロイコトリエンB4受容体の心筋梗塞での役割
- Author(s)
  黒瀬等、西原弘朗、大原広貴、長坂明臣、仲矢道雄
- Organizer
  第13回生命科学研究会
- Place of Presentation
  JRタワーホテル日航札幌、札幌
- Year and Date
  2014-06-20 – 2014-06-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] Role of superoxide anion in TNF-a-induced p38 MAPK activation in cardiac fibroblasts
- Author(s)
  Murakami, T., Takakuri, S., Sumimoto, H., INishida, M., Ichihara, K., Kurose, H
- Organizer
  The 80th Japan Pharmacological Society Meeting
- Place of Presentation
  Nagoya International Convention Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] Role of G_α<12/13> in angiotensin II-induced cardiac fibrosis
- Author(s)
  Narita, Y., Onohara, N., Nishida, M., Sato, Y., Nagao, T., Kurose, H
- Organizer
  The 80th Japan Pharmacological Society Meeting
- Place of Presentation
  Nagoya International Convention Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] Roles of TRPC channel in the heart
- Author(s)
  Kurose, H
- Organizer
  The 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects
- Place of Presentation
  Shizuoka Convention Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] βアレスチンを介したバイアス型シグナリング
- Author(s)
  黒瀬等
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Invited
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心肥大におけるMFG-E8の役割解明
- Author(s)
  松田翔一、仲矢道雄、小宮詩織、長坂明臣、黒瀬等
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2014
- Place of Presentation
  大阪、近畿大学
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] The Physiological and pathological roles of cardiac fibroblasts
- Author(s)
  黒瀬等、仲矢道雄
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞時におけるプロトン感知性受容体（TDAG8)の役割解明
- Author(s)
  西俊英、長坂明臣、仲矢道雄、岡島史和、黒瀬等
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25253011
[Presentation] 心筋梗塞におけるロイコトリエンB4受容体の機能解析及びその受容体拮抗薬を用いた新規心筋梗塞治療法の開発
- Author(s)
  大原広貴、仲矢道雄、西原弘朗、渡健治、長坂明臣、黒瀬等
- Organizer
  第13回次世代を担う若手ファーマバイオフォーラム 2014
- Place of Presentation
  富山国際会議場富山国際会議場
- Year and Date
  2014-09-20 – 2014-09-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] Gタンパク質共役型受容体の活性を調節する分子群の疾患での役割
- Author(s)
  黒瀬等、仲矢道雄
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] アポトーシス細胞の貪食におけるGRK6の関与
- Author(s)
  橋本明子、仲矢道雄、田島充、大場三奈、西原弘朗、黒瀬等
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] 心筋梗塞時におけるGRK5の役割解明
- Author(s)
  藤野美香、仲矢道雄、野田誠、高嶋美由紀、黒瀬等
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] マクロファージに発現するβ-アレスチン2による心筋梗塞後の炎症応答抑制メカニズム
- Author(s)
  渡健治、仲矢道雄、西田基宏、黒瀬等
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] 心筋梗塞時におけるロイコトリエンB4受容体の役割
- Author(s)
  大原広貴、仲矢道雄、西原弘朗、渡健治、長坂明臣、黒瀬等
- Organizer
  生体機能と創薬シンポジウム 2014
- Place of Presentation
  近畿大学東大阪キャンパス 39号館（薬学部）
- Year and Date
  2014-08-28 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PUBLICLY-25116716
[Presentation] Gタンパク質共役型受容体のGタンパク質依存性と非依存性の細胞応答
- Author(s)
  黒瀬等
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀
- Invited
- Data Source
  KAKENHI-PROJECT-23659043
[Presentation] Inhibition of angiotensin II signaling by ATP-stimulated NFAT activation in rat cardiac fibroblasts
- Author(s)
  Suda, R., Onohara, N., Sato, Y., Nishida, M., Kurose, H
- Organizer
  The 80th Japan Pharmacological Society Meeting
- Place of Presentation
  Nagoya International Convention Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[Presentation] Role of TRPC3/TRPC6 in angiotensin II receptor-induced hypertrophic responses in cardiomyocytes
- Author(s)
  Nishida, M., Onohara, N., Inoue, R., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H
- Organizer
  The 80th Japan Pharmacological Society Meeting
- Place of Presentation
  Nagoya International Conference Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390028
[]

1. NAGAO Taku (30217971)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. NAKAYA Michio (80464387)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
3. 榎本武美 (80107383)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 花岡文雄 (50012670)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. ADACHI-AKAHANE Satomi (00184185)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 長坂明臣 (10723877)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
7. 宇井理生 (50001037)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 堅田利明 (10088859)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NISHIDA Motohiro (90342641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 24 results
10. KAWANISHI Toru (40124383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KOBAYASHI Hiroyuki (20346810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. NOMATA Yasuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. SEIICH Sakamoto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 有澤光弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 輿水崇鏡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 西村明幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 横溝岳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 岡村孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 田中宏幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 茂木千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kurose Hitoshi 黒瀬 等

黒瀬 等 クロセ ヒトシ

KUROSE Hitoshi 黒瀬 等

Research Projects

Research Products

Co-Researchers

G12ファミリーのGタンパク質を介したシグナルの解析Principal Investigator

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Analysis of the roles and interaction of various cells including myofibroblasts involved in fibrosis after myocardial infarctionPrincipal Investigator

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心筋梗塞におけるロイコトリエンB4受容体の役割解析Principal Investigator

Principal Investigator

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Roles of extracellular environment and various cells carrying different function for cardiac fibrosisPrincipal Investigator

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Attempt of G protein-coupled receptor kinase-interacting proteins involved in engulfment of apoptotic cells and role of the receptor kinase in heart diseasePrincipal Investigator

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Role of GRK in engulfment of apoptotic cellsPrincipal Investigator

Principal Investigator

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Roles of Voltage- and cation-independent TRPC channels in cardiac hypertrophyPrincipal Investigator

Principal Investigator

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クラスリンのエンドサイトーシスとは関係しない細胞内シグナリング経路への役割解析Principal Investigator

Principal Investigator

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The mechanism of G protein-mediated cardiac fibrosisPrincipal Investigator

Principal Investigator

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mechanistic analysis of cardiac functions by building G protein signal networkPrincipal Investigator

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Establishment of a role of reactive oxygen species as a second messengerPrincipal Investigator

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mRNA結合タンパク質の機能を阻害するペプチドの創製と細胞現象への適用Principal Investigator

Principal Investigator

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Principal Investigator

Project Period (FY)

Kurose Hitoshi 黒瀬等

黒瀬等クロセヒトシ

KUROSE Hitoshi 黒瀬等