Shiraki Takuma 白木琢磨

… Alternative Names

Takuma Shiraki 白木琢磨

SHIRAKI Takuma 白木琢磨

白木琢磨シラキタクマ

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Researcher Number	10311747
Other IDs
Affiliation (Current)	2025: 近畿大学, 生物理工学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 近畿大学, 生物理工学部, 准教授 2011 – 2013: 近畿大学, 生物理工学部, 准教授 2010: 東北大学, 医学系研究科, 助教 2008 – 2009: Tohoku University, 大学院・医学系研究科, 助教 2008: Tohoku University, 大学院医学系研究科, 助教 … More 2007: 大阪大学, 蛋白質研究所, 寄附研究部門助教 2007: Osaka University, 蛋白質研究所寄附研究部門, 助教 2006: 大阪大学, 蛋白質研究所, 寄附研究部門助手 2002: 京大, 情報学研究科, 助手 2001: 京都大学, 大学院・情報学研究科, 助手 2000 – 2001: 京都大学, 情報学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Environmental physiology (including Physical medicine and Nutritional physiology) / Basic Section 42010:Animal production science-related / Biological Sciences / General medical chemistry / Living organism molecular science Except Principal Investigator Environmental physiology (including Physical medicine and Nutritional physiology) / Basic Section 43020:Structural biochemistry-related / Biological Sciences
Keywords	Principal Investigator 核内受容体 / メタボローム / 転写制御 / 共有結合 / 豚血清 / エコフィード / 脂肪細胞分化誘導活性 / NMRメタボローム / 肉質理化学分析 / 自動化 … More / ビッグデータ / 個体差 / 豚肉質 / メタゲノム / 機械学習 / NMR / 血清メタボローム / 肉質 / 畜産 / ケミカルバイオロジー / プロトポルフィリン症 / 生活習慣病 / ヘム合成 / 脂質代謝 / 動脈硬化 / マクロファージ / ヘム代謝 / ポルフィリア / ユビキチン / 蛋白質分解 / 核外排出抑制 / ポリユビキチン化 / 多重レポーター遺伝子 / 転写活性化キネティクス / エイコサノイド / セロトニン / シグナル伝達 / ストップトフロー / キネティクス / 活性発現の分子機構 / 受容体型グアニレートシクラーゼB / 環状ヌクレオチド依存性カチオンチャンネル / 熱ショックタンパク質90 / 温度受容ニューロン / in situ hybridization / two-hybrid system / 免疫沈降法 / Fura2顕微測光法 / 熱ショックタンパク質90kDa / 受容体型グアニレートシクラーゼ / cGMP / 後根神経節 … More Except Principal Investigator 冷細胞 / パッチクランプ / センサー / 温度受容器 / CMR1 / カチオンチャンネル / 細胞内Caイメージング / 後根神経節 / サーモスタット / イオンチャンネル / NMR / 分子運動性 / ガン創薬 / タンパク質 / アロステリー / prostaglandin receptor / brown adipose tissue / medullary raphe nucleus / brain endothelial cells / fever / cyclooxygenase / prostaglandin E synthase / PGE合成酵素 / EP3受容体 / 縫線核 / 血管内皮細胞 / シクロオキシゲナーゼ-2 / くも膜 / プロスタグランジン輸送体 / ホスホリパーゼA2 / プロスタグランジン / GABA / プロスタグランジン受容体 / 褐色脂肪組織 / 延髄縫線核 / 脳血管内皮細胞 / 発熱 / シクロオキシゲナーゼ / プロスタグランジンE合成酵素 / Ca imaging / transducer / comparator / patch-clamp / cold receptor / 温度調節器 / 相転移 / Caイメージング / トランスジューサ / 比較器 / パッチクランプ記録 / 冷受容体 / プロテオミクス / 核磁気共鳴 / X線結晶構造解析 / 立体構造解析 / 転写共役因子 / 脂肪酸代謝物 / 転写制御 / 脂肪酸 / 転写調節因子 / 蛋白質立体構造 / 脂質代謝物 / 核内受容体 / ホメオスターシス / バイモダル受容 / メントール受容体 / 分子構造 / 系統発生 / 体温調節 / 感覚器 / 単離細胞 / 個体 / 反射系 / MED / 温細胞 / 温度比較器 Less

新規アロステリック薬発見を目指したガン糖代謝関連タンパク質の動的分子構造解析
- Principal Investigator
  
  櫻井一正
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kindai University
Analytical tools to utilize livestock big data for improving meat qualityPrincipal Investigator
- Principal Investigator
  
  Takuma Shiraki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kindai University
疾患において変動する代謝物リガンドによる核内受容体ＰＰＡＲｇの機能制御Principal Investigator
- Principal Investigator
  
  白木琢磨
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kinki University
Regulation of nuclear receptor activity by intracellular signals and ligandsPrincipal Investigator
- Principal Investigator
  
  SHIRAKI Takuma
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kinki University
Kinetic analyses of nuclear receptor activationPrincipal Investigator
- Principal Investigator
  
  SHIRAKI Takuma
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Tohoku University
  Osaka University
Structural basis of functional coupling between transcription and cellular metabolism
- Principal Investigator
  
  MORIKAWA Kosuke
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Osaka University
カプサイシン受容体における活性化閾温度の決定機構Principal Investigator
- Principal Investigator
  
  白木琢磨
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
バイモダル受容
- Principal Investigator
  
  小林茂夫
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
Analysis of brain mechanism of fever using molecular probes for PGE synthesizing enzymes and PGE receptors.
- Principal Investigator
  
  MATSUMURA Kiyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
感覚器は比較器か?
- Principal Investigator
  
  KOBAYSHI Shigeo
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
熱ショックタンパク質は温度感覚に関与するか?Principal Investigator
- Principal Investigator
  
  白木琢磨
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
単離した細胞による温度調節系の自律的形成
- Principal Investigator
  
  小林茂夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
生体が持つサーモスタットの動作原理と分子基盤
- Principal Investigator
  
  小林茂夫
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Kyoto University
Ionic basis of cold receptors in cultured sensory cells of rats
- Principal Investigator
  
  KOBAYSHI Shigeo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  KYOTO UNIVERSITY

[Book] 食と健康を結ぶメディカルサイエンス（編集＝内田　浩二）2020
- Author(s)
  白木琢磨
- Total Pages
  242
- Publisher
  羊土社
- ISBN
  9784758103879
- Data Source
  KAKENHI-PROJECT-20K06383
[Book] 薬が作用するということ」化学と生物(3月号)2013
- Author(s)
  白木琢磨
- Publisher
  国際文献社
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 化学と生物、「薬が作用するということ」2013
- Author(s)
  白木琢磨
- Total Pages
  2
- Publisher
  国際文献社
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 化学と生物　３月号 pp193-195「薬が作用するということ」2013
- Author(s)
  白木琢磨
- Total Pages
  198
- Publisher
  株式会社　国際文献社
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 企画特集「タンパク質構造機能相関再考」(8月号)2013
- Author(s)
  木下賢吾, 白木琢磨
- Publisher
  生化学(日本生化学会)
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 生化学　総説「生体内代謝をモニターする転写システム：核内受容体PPARγを介した代謝ネットワーク間のクロストーク」2013
- Author(s)
  白木琢磨、和久剛、森川耿右
- Total Pages
  12
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PUBLICLY-24116524
[Book] 生化学　企画特集「タンパク質構造機能相関再考」2013
- Author(s)
  白木琢磨、木下賢吾　企画編集
- Total Pages
  70
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PUBLICLY-24116524
[Book] 生化学　特集「タンパク質構造機能相関再考」2013
- Author(s)
  白木琢磨、木下賢吾企画編集
- Total Pages
  70
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 生化学総説「生体内代謝をモニターする転写システム：核内受容体PPARγを介した代謝ネットワーク間のクロストーク」2013
- Author(s)
  白木琢磨、和久剛、森川耿右
- Total Pages
  12
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 生体内代謝物をモニターする転写システム:核内受容体PPARによる転写を介した代謝ネットワーク間のクロストーク(9月号)2013
- Author(s)
  白木琢磨, 和久剛, 森川耿右
- Publisher
  生化学(日本生化学会)
- Data Source
  KAKENHI-PROJECT-23590324
[Book] 化学と生物「薬が作用するということ」2013
- Author(s)
  白木琢磨
- Total Pages
  2
- Publisher
  国際文献社
- Data Source
  KAKENHI-PUBLICLY-24116524
[Book] 化学と生物　３月号　pp193-195「薬が作用するということ」2013
- Author(s)
  白木琢磨
- Total Pages
  198
- Publisher
  株式会社　国際文献社
- Data Source
  KAKENHI-PUBLICLY-24116524
[Book] 分子生物学会編「なぜなぜ生物学」2010
- Author(s)
  白木琢磨(共著)
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-18GS0316
[Book] 活性酸素シグナル酸化ストレス最前線, (実験医学増刊号)2009
- Author(s)
  白木琢磨
- Publisher
  親電子性リガンドセンサーとしてのPPARγ
- Data Source
  KAKENHI-PROJECT-19710187
[Book] 実験医学増刊「活性酸素シグナルと酸化ストレス」「親電子性リガンドセンサーとしての核内受容体PPARγ」205-2112009
- Author(s)
  白木琢磨
- Total Pages
  242
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18GS0316
[Book] 生化学, (79)2007
- Author(s)
  白木琢磨
- Publisher
  核内受容体PPARγの機能と内在性リガンドによる活性調節
- Data Source
  KAKENHI-PROJECT-19710187
[Journal Article] Distinct NMR Views Leverage New Strategies in Drug Discovery2024
- Author(s)
  井上直也、白木琢磨、米澤康滋、櫻井一正
- Journal Title
  
  近畿大学先端技術総合研究所紀要
  
  Volume: 29 Issue: 29 Pages: 1-9
- DOI
  10.15100/0002000987
- ISSN
  13468693
- URL
  https://kindai.repo.nii.ac.jp/records/2000987
- Year and Date
  2024-03-31
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06106
[Journal Article] How to expand the scale and diversity of chemical library2023
- Author(s)
  Kiyooka, K., Sakurai, K., Yonezawa, Y. and Shiraki, T.
- Journal Title
  
  Memoirs of Institute of Advanced Technology, Kindai University
  
  Volume: 28 Pages: 1-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06106
[Journal Article] How to expand the scale and diversity of chemical library2023
- Author(s)
  Kiyooka, K., Sakurai, K., Yonezawa, Y. and Shiraki, T.
- Journal Title
  
  Memoirs of Institute of Advanced Technology, Kindai University
  
  Volume: 28 Pages: 1-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06383
[Journal Article] Meat Quality Characteristics of Japanese Black Cattle Brand Beef Produced under Eco-Feed Feeding Conditions2022
- Author(s)
  MATSUHASHI, T., NAKAO, Y., GOTODA, M., KAMEI, T., MIYAMOTO, Y. and SHIRAKI, T.
- Journal Title
  
  Memoirs of Institute of Advanced Technology, Kindai University
  
  Volume: 27 Pages: 7-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06383
[Journal Article] -Research Note- High Pressure Protein Research Center's Efforts to Explore Allosteric Regulators2022
- Author(s)
  Shiraki, T., Sakurai, K. and Yonezawa, Y.
- Journal Title
  
  Memoirs of Institute of Advanced Technology, Kindai University
  
  Volume: 27 Pages: 15-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06383
[Journal Article] Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation.2014
- Author(s)
  Hada, H., Shiraki, T., Watanabe-Matsui, M., and Igarashi, K.
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: in press Issue: 7 Pages: 2351-2360
- DOI
  10.1016/j.bbagen.2014.02.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25860203
[Journal Article] Transactivation by Hesperetin Glucuronides is Distinct from That by a Thiazolidine-2,4-dione Agent.2014
- Author(s)
  Kanae Gamo, K., Shiraki, T., Matsuura, N., and Miyachi, H.
- Journal Title
  
  CHEM.PHARM.BULL.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] Transactivation by Hesperetin Glucuronides is Distinct from That by a Thiazolidine-2,4-dione Agent2014
- Author(s)
  Gamo, K., Shiraki, T., Matsuura, N., Miyachi, H.
- Journal Title
  
  CHEM.PHARM.BULL.
  
  Volume: 62 Pages: 491-493
- URL
  https://www.jstage.jst.go.jp/article/cpb/62/5/62_c14-00021/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] Transactivation by Hesperetin Glucuronides is Distinct from That by a Thiazolidine-2,4-dione Agent.2014
- Author(s)
  Gamo, K., Shiraki, T., Matsuura, N., and Miyachi, H.
- Journal Title
  
  CHEM.PHARM.BULL.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24116524
[Journal Article] Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism2012
- Author(s)
  Li, J., Shiraki, T., Igarashi, K.
- Journal Title
  
  FEBS Lett.
  
  Volume: 586 Pages: 448-454
- URL
  http://www.sciencedirect.com/science/article/pii/S0014579312000610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] Bach1 as a regulator of mitosis, beyond its transcriptional function2012
- Author(s)
  Li, J., Shiraki, T. Igarashi, K.
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 5 Pages: 1-3
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502211/
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism.2012
- Author(s)
  Li, J., Shiraki, T., Igarashi, K.
- Journal Title
  
  FEBS Lett.
  
  Volume: 586 Issue: 2 Pages: 448-454
- DOI
  10.1016/j.febslet.2008.12.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524
[Journal Article] Transcription-independent role of Bach1 in mitosis2012
- Author(s)
  Jie Li, Takuma Shiraki, Kazuhiko Igarashi
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Issue: 4 Pages: 448-454
- DOI
  10.1016/j.febslet.2012.01.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] Bach1 as a regulator of mitosis, beyond its transcriptional function.2012
- Author(s)
  Li, J., Shiraki, T., Igarashi, K.
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 5 Issue: 5 Pages: 1-3
- DOI
  10.4161/cib.21149
- Data Source
  KAKENHI-PROJECT-23590324, KAKENHI-PUBLICLY-24116524
[Journal Article] Detecting structural similarity of ligand interactions in the lipid metabolic system including enzymes, lipid-binding proteins and nuclear receptors.2011
- Author(s)
  Shionyu-Mitsuyama, C., Waku, T., Shiraki, T., Oyama, T., Shirai, T., Morikawa, K.
- Journal Title
  
  Protein Eng Des Sel 24
  
  Pages: 397-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Detecting structural similarity of ligand interactions in the lipid metabolic system including enzymes, lipid binding proteins, and nuclear receptors.2011
- Author(s)
  Shionyu-Matsuyama, C., Waku, T., Shiraki, T., Oyama, T., Shirai, T., Morikawa, K.
- Journal Title
  
  PEDS
  
  Volume: 24 Pages: 397-403
- URL
  http://peds.oxfordjournals.org/content/24/4/397.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590324
[Journal Article] The nuclear receptor PPARy individually responds to serotonin-and fatty acid-metabolites.2010
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Maebara, K., Nakamori, R., Morikawa, K.
- Journal Title
  
  EMBO J 29
  
  Pages: 3395-3407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor gamma activity through the direct binding to the activation function-1 domain2010
- Author(s)
  Fujimoto, Y., Shiraki, T., Horiuchi, Y., Waku, T., Shigenaga, A., Otaka, A., Ikura, T., Igarashi, K., Aimoto, S., Tate, S., Morikawa, K.
- Journal Title
  
  J Biol Chem 285(5)
  
  Pages: 3126-3132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Structural insight into PPARy activation through covalent modification with endogenous fatty acids.2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Fujimoto, Y., Maebara, K., Kamiya, N., Jingami, H., Morikawa, K.
- Journal Title
  
  J Mol Biol 385
  
  Pages: 188-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Fujimoto, Y., Maebara, K., Kamiya, N., Jingami, H., Morikawa, K.
- Journal Title
  
  J Mol Biol 385
  
  Pages: 188-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Atomic structure of mutant PPARγ LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARy/RXRa function by covalently bound ligands.2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Morikawa, K.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Structural insight into PPARγ activation through covalent modification with endogenous fatty acids2009
- Author(s)
  Waku, T.^*, Shiraki, T.^*, Oyama, T., Fujimoto, Y., Maebara, K., Kamiya, N., Jingami, H., and Morikawa, K
- Journal Title
  
  J. Mol. Biol 388
  
  Pages: 188-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710187
[Journal Article] Structural insight into PPARγ activation through covalent modification with endogenous fatty acids2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Fujimoto, Y., Maebara, K., Kamiya, N., Jingami, H. & Morikawa, K.
- Journal Title
  
  J. Mol. Biol. 385
  
  Pages: 188-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands2009
- Author(s)
  Waku, T., Shiraki T., Oyama T., Morikawa. K.
- Journal Title
  
  FEBS Lett 583
  
  Pages: 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Structural insight into PPARγ activation through covalent modification with endogenous fatty acids2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Fujimoto, Y., Maebara, K., Kamiya, N., Jingami, H., Morikawa, K
- Journal Title
  
  J. Mol. Biol 388
  
  Pages: 188-199
- Data Source
  KAKENHI-PROJECT-19710187
[Journal Article] Atomic structure of mutant PPARγ LBD complexed with 15d-PGJ2 : novel modulation mechanism of PPARγ/RXRα function by covalently bound ligands2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., Morikawa, K
- Journal Title
  
  FEBS Lett 853
  
  Pages: 320-324
- Data Source
  KAKENHI-PROJECT-19710187
[Journal Article] Atomic structure of mutant PPARγ LBD complexed with 15d-PGJ_2 : novel modulation mechanism of PPARγ/RXRα function by covalently bound ligands2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T., and Morikawa, K.
- Journal Title
  
  FEBS Lett 853
  
  Pages: 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710187
[Journal Article] Atomic structure of mutant PPARγLBD complexed with 15d-PGJ2 : novel modulation mechanism of PPARγ/RXRαfunction by covalently bound ligands2009
- Author(s)
  Waku, T., Shiraki, T., Oyama, T. & Morikawa, K.
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 320-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Activation mechanism of PPARg by its endogenous ligands.2007
- Author(s)
  Shiraki, T.
- Journal Title
  
  生化学 79
  
  Pages: 960-964
- Data Source
  KAKENHI-PROJECT-18GS0316
[Journal Article] Activation mechanism of PPARg bu its endogenous ligands.2007
- Author(s)
  Shiraki. T.
- Journal Title
  
  生化学 79
  
  Pages: 960-964
- Data Source
  KAKENHI-PROJECT-19710187
[Patent] 核内受容体に結合するリガンド2007
- Inventor(s)
  白木琢磨
- Industrial Property Rights Holder
  国立大学法人大阪大学
- Filing Date
  2007-03-29
- Overseas
- Data Source
  KAKENHI-PROJECT-19710187
[Patent] 核内受容体に結合するリガンド2006
- Inventor(s)
  白木琢磨
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Number
  2006-117239
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] 牛伝染性リンパ腫ウイルス感染を早期に検出する新規バイオマーカーの探索2022
- Author(s)
  車取侑香, 古谷眞椰, 猪島康雄, 松本和也, 白木琢磨, 松橋珠子
- Organizer
  第５９回肉用牛研究会和歌山大会
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] AIを飼いならす：構造多様性を持った化合物ライブラリーの作成2022
- Author(s)
  清岡和俊, 白木琢磨
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] AIを飼いならす：構造多様性を持った化合物ライブラリーの作成2022
- Author(s)
  清岡和俊, 白木琢磨
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06106
[Presentation] ORの数理：バラツキを生み出す生命システム2022
- Author(s)
  白木琢磨
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] 牛個体栄養管理のための生体血清メタボローム解析2022
- Author(s)
  清岡和俊, 鈴木文香, 小西真奈, 前田恵助, 松橋珠子, 白木琢磨
- Organizer
  第５９回肉用牛研究会和歌山大会
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] エコフィードを給与して生産された紀州和華牛の肉質特性探索2022
- Author(s)
  長堀百花, 後藤田実咲, 宮本泰成, 後藤洋人, 白木琢磨, 松橋珠子
- Organizer
  第５９回肉用牛研究会和歌山大会
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] 確率論的に振る舞う豚の調理法：ビッグデータ時代の畜産学2021
- Author(s)
  白木琢磨
- Organizer
  日本環境変異原ゲノム学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] メタボロームから考える健康：畜産学から栄養学へ2021
- Author(s)
  白木琢磨
- Organizer
  日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] 生体分子のゆらぎと表現型のバラツキ2021
- Author(s)
  白木琢磨
- Organizer
  日本蛋白質科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] 栄養学5.02020
- Author(s)
  白木琢磨
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06383
[Presentation] 核内受容体に作用する生体内代謝物の分子解剖2014
- Author(s)
  Shiraki, T.
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜
- Invited
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Multiple metabolic pathways regulate PPARγ in multiple ways2013
- Author(s)
  Shiraki, T., Morikawa, K., Igarashi, K.
- Organizer
  CSHL meeting 2013　“Metabolic signaling & Disease: From cell to organism”
- Place of Presentation
  コールドスプリングハーバー研究所
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Metabolite-mediated regulation of PPARα in health and disease2013
- Author(s)
  Masaya Ohishi, Yuji Shimomura, Ryo Tsukahara, Naoya Arahi and Takuma Shiraki
- Organizer
  国際シンポジウム（第5回班会議）
- Place of Presentation
  兵庫県淡路市
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] Multiple metabolic pathways regulate PPARg in multiple ways2013
- Author(s)
  Shiraki, T., Morikawa, K., Igarashi, K.
- Organizer
  CSHL meeting
- Place of Presentation
  Cold Spring Harbor Laboratory, NY, USA
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Multiple metabolic pathways regulate PPARγ in multiple ways2013
- Author(s)
  Takuma Shiraki, Kosuke Morikawa, and Kazuhiko Igarashi
- Organizer
  CSHL meeting 2013　“Metabolic signaling & Disease: From cell to organism”
- Place of Presentation
  コールドスプリングハーバー研究所
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] One receptor senses two ligands; the nuclear receptor PPARγ monitors multiple cellular metabolism2012
- Author(s)
  Shiraki T., Morikawa K., and Igarashi K.
- Organizer
  Metabolism, Diet and Disease
- Place of Presentation
  Washington DC（米国）
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Structural basis for the activation of the nuclear receptor, PPARgamma, by fatty acid- and serotonin metabolites2012
- Author(s)
  Waku T, Shiraki T, Oyama T, Shionyu C and Morikawa K
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] SRC1によるPPARgのアゴニスト依存的な構造変化の認識2012
- Author(s)
  橋本愛美、野坂佳加、白木琢磨、楯真一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] 組換えヘモペキシンを用いた細胞外ヘムによる遺伝子制御機構の解明2012
- Author(s)
  羽田浩士、白木琢磨、松井美紀、五十嵐和彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] 組換えヘモペキシンを用いた細胞外ヘムによる遺伝子制御機構の解明2012
- Author(s)
  羽田浩士、白木琢磨、松井美紀、五十嵐和彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] One receptor senses two ligands; the nuclear receptor PPARγ monitors multiple cellular metabolism2012
- Author(s)
  Shiraki T., Morikawa K., and Igarashi K.
- Organizer
  Metabolism, Diet and Disease
- Place of Presentation
  Washington DC（米国）
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] Structural basis for the activation of the nuclear receptor, PPARgamma, by fatty acid- and serotonin metabolites2012
- Author(s)
  Waku, T., Shiraki, T., Morikawa, K.
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] One receptor senses two ligands; the nuclear receptor PPARg monitors multiple cellular metabolism2012
- Author(s)
  Shiraki, T., Morikawa, K., Igarashi, K.
- Organizer
  Metabolism, Diet and Disease
- Place of Presentation
  Georgetown University Hotel and Conference Center, Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] SRC1によるPPARgのアゴニスト依存的な構造変化の認識2012
- Author(s)
  橋本愛美、野坂佳加、白木琢磨、楯真一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-24116524
[Presentation] Structural basis for the activation of the nuclear receptor, PPARgamma, by fatty acid- and serotonin metabolites2012
- Author(s)
  Waku T, Shiraki T, Oyama T, Shionyu C and Morikawa K
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Serotonin metabolites act on PPARg as ligands2011
- Author(s)
  Takuma Shiraki
- Organizer
  LXXVI Cold Spring Harbor Symposium
- Place of Presentation
  Cold Spring Harbor Laboratory (NY, USA)
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Sertonin metabolites act on the nuclear receptor PPARg as endogenous ligands independently of fatty-acid metabolites2011
- Author(s)
  Shiraki, T., Morikawa, K., Igarashi, K.
- Organizer
  LXXVI Cold Spring Harbor Symposium on Quantitative Biology
- Place of Presentation
  Cold Spring Harbor Laboratory, NY, USA
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] 核内受容体PPARgの機能解析：分子生物学的アプローチと生化学的アプローチ2011
- Author(s)
  白木琢磨
- Organizer
  第８４回　日本生化学会大会
- Place of Presentation
  京都国際会議場（京都府）
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] 核内受容体PPARgの機能解析:分子生物学的アプローチと生化学的アプローチ2011
- Author(s)
  白木琢磨
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23590324
[Presentation] Structural basis for the activation of the nuclear receptor, PPARgamma, by fatty acid-and serotonin metabolites2010
- Author(s)
  和久剛、白木琢磨、大山拓次、森川耿右
- Organizer
  Korea-Japan Chromatin & Epigenetics Joint Symposium 2010
- Place of Presentation
  Hyundai sungwoo resort, Hoengseong Gun(韓国)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] Proline cis/trans isomerase Pin1 regulates nuclear receptor PPARg activity through the direct binding to the AF-1 domain2010
- Author(s)
  白木琢磨、楯真一、森川耿右、五十嵐和彦
- Organizer
  転写情報DECODE・冬のワークショップ2009
- Place of Presentation
  湯沢グランドホテル(新潟)
- Year and Date
  2010-01-19
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] Activation mechanism of PPARg by oxidized fatty acids2009
- Author(s)
  白木琢磨、森川耿右
- Organizer
  JST International Symposium "Molecular mechanism of environmental response to food and oxygen III"
- Place of Presentation
  Gonryo Kaikan, Sendai
- Year and Date
  2009-02-10
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] Activation mechanism of PPARg by oxidized fatty acids2009
- Author(s)
  Takuma Shiraki, Kosuke Morikawa
- Organizer
  JST International Symposium" Molecular mechanism of environmental response to food and oxygen III"
- Place of Presentation
  Gonryo Kaikan, Sendai
- Year and Date
  2009-02-10
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] Activation mechanism of PPARy by oxidized fatty acids. JST International Symposium2009
- Author(s)
  白木琢磨., 森川取右.
- Organizer
  Molecular mechanism of environmental response to food and oxygen III
- Place of Presentation
  Sendai, Japan
- Year and Date
  2009-02-10
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] Molecular mechanism of environmental response to food and oxygen III2009
- Author(s)
  Takuma Shiraki, Kosuke Morikawa
- Organizer
  Activation mechanism of PPARg by oxidized fatty acids JST International Symposium
- Place of Presentation
  Sendai
- Year and Date
  2009-02-10
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] 内在性リガンドによる核内受容体PPARgの活性化機構の解明と創薬への応用2009
- Author(s)
  白木琢磨、和久剛、森川耿右
- Organizer
  転写情報DECODE・冬のワークショップ2009
- Place of Presentation
  越後湯沢
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] ヘム関連代謝物による核内受容体PPARgの活性制御2009
- Author(s)
  白木琢磨、森川耿右、五十嵐和彦
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] 内在性リガンドによる核内受容体PPARgの活性化機構の解明と創薬への応用2009
- Author(s)
  白木琢磨、和久剛、森川耿右
- Organizer
  転写情報DEのワークショップ 2009
- Place of Presentation
  越後湯沢
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] 内在性リガンドによる核内受容体PPARgの活性化機構の解明と創薬への応用2009
- Author(s)
  白木琢磨、和久剛、森川耿右
- Organizer
  転写情報DECODE・冬のワークショップ2009
- Place of Presentation
  越後湯沢
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] 内在性リガンドによる核内受容体PPARγの活性化機構の解明と創薬への応用.2009
- Author(s)
  白木琢磨、和久剛、森川取右
- Organizer
  転写情報DECODE・冬のワークショップ.
- Place of Presentation
  越後湯沢.
- Year and Date
  2009-01-19
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] PPARy activating process through covalent modification by endogenous fatty acids.2008
- Author(s)
  白木琢磨.
- Organizer
  Lipid Peroxidation
- Place of Presentation
  Karuizawa, Japan
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] 核内受容体PPARgammaに対する新規内在性脂肪酸リガンドの同定と受容体活性化機構2008
- Author(s)
  和久剛、白木琢磨、森川耿右
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会年大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] 脂肪酸リガンドによる核内受容体PPARγの活性化キネティクス2008
- Author(s)
  白木琢磨、和久剛、森川耿右
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会年大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] PPARγ activating process through covalent modification by endogenous fatty acids2008
- Author(s)
  白木琢磨
- Organizer
  Lipid Peroxidation 2008
- Place of Presentation
  軽井沢プリンスホテル
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] PPARγ activating process through covalent modification by endogenous fatty acids2008
- Author(s)
  白木琢磨
- Organizer
  Lipid Peroxidation 2008
- Place of Presentation
  軽井沢
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] リガンドの共通部分構造を認識する脂質シグナル系タンパク質部位の探索2008
- Author(s)
  塩生くらら、和久剛、大山拓次、白木琢磨、白井剛、森川耿右
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] 脂肪酸リガンドによる核内受容体PPARγの活性化キネティクス2008
- Author(s)
  白木琢磨、和久剛、森川耿右
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会年大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] PPAR γ activating process through covalent modification by endogenous fatty acids2008
- Author(s)
  白木琢磨
- Organizer
  Lipid Peroxidation 2008
- Place of Presentation
  軽井沢プリンスホテル
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] PPARγ activating process through covalent modification by endogenous fatty acids2008
- Author(s)
  Shiraki, T.
- Organizer
  Lipid Peroxidation
- Place of Presentation
  Karuizawa, Japan
- Year and Date
  2008-10-16
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] リガンドの共通部分構造を認識する脂質シグナル系タンパク質部位の探索2008
- Author(s)
  塩生くらら、和久剛、大山拓次、白木琢磨、白井剛、森川耿右
- Organizer
  第46回日本生物物理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] 核内受容体PPARγに対する新規内在性脂肪酸リガンドの同定と受容体活性化機構2008
- Author(s)
  和久剛、白木琢磨、森川耿右
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会年大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19710187
[Presentation] リガンドの共通部分構造を認識する脂質シグナル系タンパク質部位の探索2008
- Author(s)
  塩生くらら、和久剛、大山拓次、白木琢磨、白井剛、森川耿右
- Organizer
  第46回日本生物物理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-18GS0316
[Presentation] リガンドの共通部分構造を認識する脂質シグナル系タンパク質部位の探索2008
- Author(s)
  塩生くらら、和久剛、大山拓次、白木琢磨、白井剛、森川耿右
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-18GS0316

1. KOBAYSHI Shigeo (40124797)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. MATSUMURA Kiyoshi (10157349)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MORIKAWA Kosuke (80012665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
4. MURAYAMA Akiko (50431656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TATE Shinーichi (20216998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KIMURA Keiji (50332268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OYAMA Takuji (60423133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
8. TAKAO Toshifumi (10197048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. MATSUMURA Kyoko (40173877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HOSOKAWA Hiroshi (90359779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 彼末一之 (50127213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川岸郁郎 (80234037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 富永真琴 (90260041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 櫻井一正 (10403015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 米澤康滋 (40248753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Shiraki Takuma 白木 琢磨

Takuma Shiraki 白木 琢磨

SHIRAKI Takuma 白木 琢磨

白木 琢磨 シラキ タクマ

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Analytical tools to utilize livestock big data for improving meat qualityPrincipal Investigator

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疾患において変動する代謝物リガンドによる核内受容体ＰＰＡＲｇの機能制御Principal Investigator

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Regulation of nuclear receptor activity by intracellular signals and ligandsPrincipal Investigator

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Kinetic analyses of nuclear receptor activationPrincipal Investigator

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カプサイシン受容体における活性化閾温度の決定機構Principal Investigator

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熱ショックタンパク質は温度感覚に関与するか?Principal Investigator

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Shiraki Takuma 白木琢磨

Takuma Shiraki 白木琢磨

SHIRAKI Takuma 白木琢磨

白木琢磨シラキタクマ

[Book] 食と健康を結ぶメディカルサイエンス（編集＝内田　浩二）2020

[Book] 化学と生物　３月号 pp193-195「薬が作用するということ」2013

[Book] 生化学　総説「生体内代謝をモニターする転写システム：核内受容体PPARγを介した代謝ネットワーク間のクロストーク」2013

[Book] 生化学　企画特集「タンパク質構造機能相関再考」2013

[Book] 生化学　特集「タンパク質構造機能相関再考」2013

[Book] 生化学総説「生体内代謝をモニターする転写システム：核内受容体PPARγを介した代謝ネットワーク間のクロストーク」2013

[Book] 化学と生物　３月号　pp193-195「薬が作用するということ」2013