Nomura Norimichi 野村紀通

… Alternative Names

NOMURA Norimichi 野村紀通

NOMURA Norimiti 野村紀通

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Researcher Number	10314246
Other IDs	https://orcid.org/0000-0002-6330-2239
External Links
Affiliation (Current)	2025: 京都大学, 生命科学研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 京都大学, 医学研究科, 准教授 2016 – 2018: 京都大学, 医学研究科, 助教 2017: 京都大学, 大学院医学研究科, 助教 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2014: 京都大学, 大学院医学研究科, 助教 … More 2012: 京都大学, 大学院・医学研究科, 助教 2010 – 2011: 京都大学, 医学研究科, 助教 2005: 京大, (連合)農学研究科(研究院), 助手 2000 – 2004: 京都大学, 農学研究科, 助手 2002: 京都大学, 農学研究科, 助教授 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Structural biochemistry / Applied molecular and cellular biology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Medium-sized Section 50:Oncology and related fields / Basic Section 49060:Virology-related / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Applied molecular and cellular biology Except Principal Investigator Structural biochemistry / General medical chemistry … More / Fisheries chemistry / Basic Section 38030:Applied biochemistry-related / Complex systems / Basic Section 43030:Functional biochemistry-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Applied microbiology / Fisheries chemistry Less
Keywords	Principal Investigator 超好熱菌 / 古細菌 / 可動性イントロン / ホーミングエンドヌクレアーゼ / クライオ電子顕微鏡単粒子解析 / X線結晶構造解析 / 利己的遺伝子 / 遺伝子水平伝播 / イントロンホーミング / ゲノム多型 … More / ゲノム / ホーミング / イントロン / 遺伝子破壊 / 逆遺伝学 / 創薬ターゲット / 抗体 / 膜タンパク質 / ファージディスプレイ / 膜蛋白質 / 進化 / クライオ電子線トモグラフィー解析 / 仮足形成 / がん転移・悪性化進展 / テトラスパニン / 抗ウイルス薬 / 宿主ーウイルス相互作用 / 感染受容体 / B型肝炎ウイルス / 宿主因子 / クライオ電子顕微鏡 / エンベロープタンパク質 / ウイルス受容体 / 阻害剤 / アロステリックモジュレーター / 中分子ペプチド / 創薬 / 中分子 / 中分子創薬 / コレステロール / トランスポーター / 胆汁酸 / 高脂血症 / プァージディスプレイ / 膜輸送体 / 抗体フラグメント / 結晶化リガンド / 耐熱性酵素 / 無細胞蛋白質合成系 / バイオインフォマティックス / 制限修飾系 / 蛋白質-DNA分子間相互作用 / II型制限酵素 / 有用遺伝子資源 … More Except Principal Investigator X線結晶構造解析 / 結晶構造解析 / 膜タンパク質 / 抗体 / 創薬 / 超好熱菌 / ホーミングエンドヌクレアーゼ / 古細菌 / 膜輸送 / 構造解析 / クライオ電子顕微鏡単粒子解析 / シグナル伝達 / 構造生物学 / エンドヌクレアーゼ / Archaea / トランスポーター / GPCR / 耐熱性酵素 / 制限修飾系 / ゲノム / 脱オーファン化 / 薬剤排出輸送体 / チャネルロドプシン / フォトクロミックタンパク質 / 構造ダイナミクス / ロドプシン / 時分割X線結晶構造解析 / X線自由電子レーザー / 光遺伝学 / 病原菌 / 再構成 / 薬剤排出トランスポーター / 病原性細菌 / 多剤排出トランスポーター / 物質輸送 / 薬剤耐性 / 細菌感染症 / MFS輸送体 / 薬剤排出 / ファージディスプレイ / クライオ電子顕微鏡 / 中分子 / ウイルス感染受容体 / 中分子ペプチド / B型肝炎ウイルス / 抗ウイルス薬 / 中分子医薬品 / 創薬ターゲット / 癌 / 蛋白質 / G蛋白質共役型受容体 / タンパク質 / Gタンパク質共役型受容体 / 機能性抗体 / 睡眠 / ナルコレプシー / 薬剤開発 / ヒト膜受容体 / Crystal structure analysis / DNA-binding protein / Alteration of substrate specificity / Protein engineering / Restriction endonuclease / DNA認識機構 / 転写制御因子 / 界面活性剤 / 金属イオン / 部位特異的変異 / 結晶化 / DNA結合タンパク質 / 特異性改変 / タンパク質工学 / 制限酵素 / endonuclease / hydrogenase / thermostable enzyme / genetic resources / genome / hyperthermophilles / deep sea hydrothermal environment / 知的財産権 / 環境バイオテクノロジー / メタゲノム解析 / 有用ゲノム資源 / 海底熱水口 / ホーミングエンドヌクレアー / 深海熱水孔 / ヌクレアーゼ / など / ヒドロゲナーゼ / 遺伝子資源 / 深海熱水環境 / restriction enzyme / Intron / hydrogen bacteria / homing endonuclease / heat stable enzymes / marine hydrothermal vent / hyperthermophilic microorganism / 分子系統解析 / 好気性超好熱菌 / 好熱遺伝子群 / プロテアーゼ / イントロン / 水素細菌 / 耐熱酵素 / 海底熱水孔 / 輸送体 / 膜輸送体 / アデノシンA2a受容体 / 立体構造認識抗体 / モノクローナル抗体 / 無細胞蛋白質合成系 / バイオインフォマテイックス / タンパク質-DNA相互作用 / II型制限酵素 / 有用遺伝子資源 / 可動性イントロン / 利己的遺伝子 / 遺伝子水平伝播 / イントロンホーミング / ゲノム多型 Less

ウイルス膜蛋白質の生理的準安定構造の解明と創薬応用Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
Deorphanization of MFS-Type Multidrug Efflux Transporters: Inhibition of Drug Efflux and Physiological function
- Principal Investigator
  
  田辺幹雄
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  High Energy Accelerator Research Organization
Structural biology of the hepatitis B virus entry and its inhibitionPrincipal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto University
テトラスパニンを介した新たながん転移促進機構の解明Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kyoto University
Establishing key technologies for structure-based design of medium-sized therapeutic molecules targeting human membrane proteins
- Principal Investigator
  
  Iwata So
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
Elucidation of multidrug recognition and transport mechanisms of MFS-type multidrug efflux transporters
- Principal Investigator
  
  Mikio Tanabe
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  High Energy Accelerator Research Organization
Time-resolved XFEL crystallography and rational engineering of light-driven proteins
- Principal Investigator
  
  Iwata So
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Creation and crystallographic studies of artificial medium-sized aptamers that modulate membrane protein functionsPrincipal Investigator
- Principal Investigator
  
  Nomura Norimichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto University
Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodiesPrincipal Investigator
- Principal Investigator
  
  Nomura Norimichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Differential analysis of the crystal structures of active / inactive orexin receptor contributing to rational development of sleep control drug
- Principal Investigator
  
  Suno Ryoji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Trial for determining the structure of CXCR7
- Principal Investigator
  
  Shimamura Tatsuro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Structure determination of human membrane transporters
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Technologicaldevelopment for construction of synthetic proteins that facilitate membrane protein crystallizationPrincipal Investigator
- Principal Investigator
  
  NOMURA Norimichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Development of antibody stabilizing active or inactive state of GPCRs.
- Principal Investigator
  
  KOBAYASHI Takuya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
古細菌ゲノムに散在する可動性イントロンの集団内伝播と進化のダイナミクスPrincipal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ゲノム工学技術への応用をめざした人工レアカッター酵素の開発と分子設計原理の解明Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Large scale collection and their industrial application of hyperthemophilic archaeal genome from deep sea hydrothermal envirenments
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kyoto University
Structural analysis of endonuclease-DNA interaction and alteration of substrate specificity
- Principal Investigator
  
  KITA Keiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto University
古細菌ゲノムに散在する可動性イントロンの集団内伝播と進化のダイナミクスPrincipal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
海洋性好熱古細菌における新規制限酵素遺伝子群の網羅的開発に関する研究
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kyoto University
古細菌における制限酵素遺伝子群のゲノム規模での網羅的単離・同定Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
古細菌ゲノムの体系的・網羅的機能解析を支援する逆遺伝学的方法論の開発Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
古細菌ゲノムの体系的・網羅的機能解析を支援する逆遺伝学的方法論の開発Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
超好熱古細菌ゲノムの体系的機能解析のための分子遺伝学的基盤の構築Principal Investigator
- Principal Investigator
  
  野村紀通
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Isolation of novel thermophilic organisms from marine hydrothermal environments and the development of new catalytic functions
- Principal Investigator
  
  SAKO Yoshihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Fisheries chemistry
- Research Institution
  KYOTO UNIVERSITY

[Book] “The Intervening Removable Affinity Tag (iRAT) System for the Production of Recombinant Antibody Fragments” in Methods Mol Biol.2021
- Author(s)
  *Nomura N, Nomura Y, Sato Y and *Iwata S.
- Total Pages
  340
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] “The Intervening Removable Affinity Tag (iRAT) System for the Production of Recombinant Antibody Fragments” in Methods Mol Biol.2021
- Author(s)
  *Nomura N, Nomura Y, Sato Y and *Iwata S.
- Total Pages
  340
- Publisher
  Humana Press
- ISBN
  9781071611258
- Data Source
  KAKENHI-PROJECT-19H00923
[Book] Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy; Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)2019
- Author(s)
  Norimichi Nomura, Yayoi Nomura, Yumi Sato, So Iwata
- Total Pages
  511
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] Methods in Enzymology, Vol. 629, "Tumor Immunology and Immunotherapy; Molecular Methods" (Edited by Lorenzo Galluzzi, Nils-Petter Rudqvist)2019
- Author(s)
  Norimichi Nomura, Yayoi Nomura, Yumi Sato, So Iwata
- Total Pages
  511
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-19H00923
[Book] Methods Molecular Biology, Vol. 1700, Yamaguchi, A. and Nishino, K. (Eds.) “Bacterial Multidrug Exporters”2018
- Author(s)
  Jaenecke F., Nakada-Nakura, Y., Nagarathinam, K., Ogasawara, S., Liu, K., Hotta, Y., Iwata, S., Nomura, N., Tanabe, M
- Total Pages
  355
- Publisher
  Springer
- ISBN
  9781493974528
- Data Source
  KAKENHI-PROJECT-18K05334
[Book] Bacterial Multidrug Exporters2017
- Author(s)
  Jaenecke F., Nakada-Nakura, Y., Nagarathinam, K., Ogasawara, S., Liu, K., Hotta, Y., Iwata, S., Nomura, N., Tanabe, M
- Total Pages
  355
- Publisher
  Humana Press
- ISBN
  9781493974528
- Data Source
  KAKENHI-PROJECT-15K06968
[Book] 糖尿病学2016（第4章「GLUT5の立体構造とフルクトース輸送機構」）2016
- Author(s)
  野村紀通、岩田想
- Total Pages
  161
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] Structural basis of hepatitis B virus receptor binding2024
- Author(s)
  Asami Jinta、Park Jae-Hyun、Nomura Yayoi、Kobayashi Chisa、Mifune Junki、Ishimoto Naito、Uemura Tomoko、Liu Kehong、Sato Yumi、Zhang Zhikuan、Muramatsu Masamichi、Wakita Takaji、Drew David、Iwata So、Shimizu Toshiyuki、Watashi Koichi、Park Sam-Yong、Nomura Norimichi、Ohto Umeharu
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 31 Issue: 3 Pages: 447-454
- DOI
  10.1038/s41594-023-01191-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19447, KAKENHI-PROJECT-23K18211, KAKENHI-PROJECT-23K18239, KAKENHI-PROJECT-22K15046, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-23K23820, KAKENHI-PROJECT-23K24142, KAKENHI-PROJECT-23K27415
[Journal Article] B型肝炎ウイルスの感染受容体NTCPの構造2023
- Author(s)
  野村紀通
- Journal Title
  
  医学のあゆみ
  
  Volume: 285 Pages: 1082-1083
- Data Source
  KAKENHI-PROJECT-23K27415
[Journal Article] Structure and mechanism of oxalate transporter OxlT in an oxalate-degrading bacterium in the gut microbiota2023
- Author(s)
  Jaunet-Lahary Titouan、Shimamura Tatsuro、Hayashi Masahiro、Nomura Norimichi、Hirasawa Kouta、Shimizu Tetsuya、Yamashita Masao、Tsutsumi Naotaka、Suehiro Yuta、Kojima Keiichi、Sudo Yuki、Tamura Takashi、Iwanari Hiroko、Hamakubo Takao、Iwata So、Okazaki Kei-ichi、Hirai Teruhisa、Yamashita Atsuko
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1730-1730
- DOI
  10.1038/s41467-023-36883-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03195, KAKENHI-PROJECT-20K21392, KAKENHI-PROJECT-20K21482, KAKENHI-PROJECT-18H02388, KAKENHI-PUBLICLY-21H00404, KAKENHI-PROJECT-23K18239, KAKENHI-PROJECT-22K20632, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21H02414, KAKENHI-PROJECT-21H02446, KAKENHI-PROJECT-23K27415
[Journal Article] B型肝炎ウイルスの感染受容体NTCPの構造2023
- Author(s)
  野村紀通
- Journal Title
  
  医学のあゆみ
  
  Volume: 285 Pages: 1082-71083
- Data Source
  KAKENHI-PROJECT-19H00923
[Journal Article] Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn2+ uptake into the Golgi apparatus2023
- Author(s)
  Bui Han Ba、Watanabe Satoshi、Nomura Norimichi、Liu Kehong、Uemura Tomoko、Inoue Michio、Tsutsumi Akihisa、Fujita Hiroyuki、Kinoshita Kengo、Kato Yukinari、Iwata So、Kikkawa Masahide、Inaba Kenji
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4770-4770
- DOI
  10.1038/s41467-023-40521-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18239, KAKENHI-PLANNED-19H05777, KAKENHI-PLANNED-21H05248, KAKENHI-PLANNED-21H05253, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21H04758, KAKENHI-PROJECT-23K27415
[Journal Article] B型肝炎ウイルスの感染受容体NTCPの構造2023
- Author(s)
  野村紀通
- Journal Title
  
  医学のあゆみ
  
  Volume: 285 Pages: 1082-1083
- Data Source
  KAKENHI-PLANNED-19H05777
[Journal Article] B型肝炎ウイルスの感染受容体NTCPの構造2023
- Author(s)
  野村紀通
- Journal Title
  
  医学のあゆみ
  
  Volume: 285 Pages: 1082-1083
- Data Source
  KAKENHI-PROJECT-23K18239
[Journal Article] Structure, mechanism and lipid-mediated remodeling of the mammalian Na+/H+ exchanger NHA22022
- Author(s)
  Matsuoka Rei、Fudim Roman、Jung Sukkyeong、Zhang Chenou、Bazzone Andre、Chatzikyriakidou Yurie、Robinson Carol V.、Nomura Norimichi、Iwata So、Landreh Michael、Orellana Laura、Beckstein Oliver、Drew David
- Journal Title
  
  Nature Structural and Molecular Biology
  
  Volume: 29 Issue: 2 Pages: 108-120
- DOI
  10.1038/s41594-022-00738-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers.2022
- Author(s)
  Hosaka, T. et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 119 Issue: 9
- DOI
  10.1073/pnas.2117433119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-20H05450, KAKENHI-PROJECT-18H04136, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-22H00557, KAKENHI-PROJECT-21H02439, KAKENHI-ORGANIZER-19H05776, KAKENHI-PLANNED-19H05781, KAKENHI-PLANNED-19H05777
[Journal Article] Structure of the?bile acid transporter?and HBV receptor NTCP2022
- Author(s)
  Asami Jinta、Kimura Kanako Terakado、Fujita-Fujiharu Yoko、Ishida Hanako、Zhang Zhikuan、Nomura Yayoi、Liu Kehong、Uemura Tomoko、Sato Yumi、Ono Masatsugu、Yamamoto Masaki、Noda Takeshi、Shigematsu Hideki、Drew David、Iwata So、Shimizu Toshiyuki、Nomura Norimichi、Ohto Umeharu
- Journal Title
  
  Nature
  
  Volume: 606 Issue: 7916 Pages: 1021-1026
- DOI
  10.1038/s41586-022-04845-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15046, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21J12207, KAKENHI-PROJECT-22J14378, KAKENHI-PROJECT-21K19207, KAKENHI-PROJECT-23K23820, KAKENHI-PLANNED-19H05777
[Journal Article] Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice.2022
- Author(s)
  Al-Habsi M, Chamoto K, Matsumoto K, Nomura N, Zhang B, Sugiura Y, Sonomura K, Maharani A, Nakajima Y, Wu Y, Nomura Y, Menzies R, Tajima M, Kitaoka K, Haku Y, Delghandi S, Yurimoto K, Matsuda F, Iwata S, Ogura T, Fagarasan S, Honjo T.
- Journal Title
  
  Science
  
  Volume: 378 Issue: 6618
- DOI
  10.1126/science.abj3510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20592, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20K07615, KAKENHI-PLANNED-19H05777
[Journal Article] Structure of SARS-CoV-2 membrane protein essential for virus assembly2022
- Author(s)
  Zhang Zhikuan、Nomura Norimichi、Muramoto Yukiko、Ekimoto Toru、Uemura Tomoko、Liu Kehong、Yui Moeko、Kono Nozomu、Aoki Junken、Ikeguchi Mitsunori、Noda Takeshi、Iwata So、Ohto Umeharu、Shimizu Toshiyuki
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4399-4399
- DOI
  10.1038/s41467-022-32019-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15046, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21K19207, KAKENHI-PLANNED-18H05426, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-23K23820, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-20H03380
[Journal Article] Structural insights into the G protein selectivity revealed by the human EP3-Gi signaling complex2022
- Author(s)
  Ryoji Suno, Yukihiko Sugita, Kazushi Morimoto, Hiroko Takazaki, Hirokazu Tsujimoto, Mika Hirose, Chiyo Suno-Ikeda, Norimichi Nomura, Tomoya Hino, Asuka Inoue, Kenji Iwasaki, Takayuki Kato, So Iwata, Takuya Kobayashi
- Journal Title
  
  Cell Rep.
  
  Volume: 40(11) Issue: 11 Pages: 111323-111323
- DOI
  10.1016/j.celrep.2022.111323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19360, KAKENHI-PLANNED-21H05112, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-19H03428, KAKENHI-PUBLICLY-22H04753, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-20H03434
[Journal Article] The structural basis of bacterial manganese import2021
- Author(s)
  Neville Stephanie L.、Sj?hamn Jennie、Watts Jacinta A.、MacDermott-Opeskin Hugo、Fairweather Stephen J.、Ganio Katherine、Carey Hulyer Alex、McGrath Aaron P.、Hayes Andrew J.、Malcolm Tess R.、Davies Mark R.、Nomura Norimichi、Iwata So、O’Mara Megan L.、Maher Megan J.、McDevitt Christopher A.
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 32
- DOI
  10.1126/sciadv.abg3980
- NAID
  120007149018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] The structure of MgtE in the absence of magnesium provides new insights into channel gating.2021
- Author(s)
  Jin F, Sun M, Fujii T, Yamada Y, Wang J, Maturana AD, Wada M, Su S, Ma J, Takeda H, Kusakizako T, Tomita A, Nakada-Nakura Y, Liu K, Uemura T, Nomura Y, Nomura N, Ito K, Nureki O, Namba K, Iwata S, Yu Y, Hattori M.
- Journal Title
  
  PLoS Biology
  
  Volume: 19 Issue: 4 Pages: e3001231-e3001231
- DOI
  10.1371/journal.pbio.3001231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-20K15754, KAKENHI-PLANNED-19H05777
[Journal Article] Molecular mechanism of SbmA, a promiscuous transporter exploited by antimicrobial peptides2021
- Author(s)
  Ghilarov Dmitry、Inaba-Inoue Satomi、Stepien Piotr、Qu Feng、Michalczyk Elizabeth、Pakosz Zuzanna、Nomura Norimichi、Ogasawara Satoshi、Walker Graham Charles、Rebuffat Sylvie、Iwata So、Heddle Jonathan Gardiner、Beis Konstantinos
- Journal Title
  
  Science Advances
  
  Volume: 7 Issue: 37
- DOI
  10.1126/sciadv.abj5363
- NAID
  120007147067
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] Cryo-EM structure of the human MT1-Gi signaling complex.2021
- Author(s)
  Okamoto, H. H., Miyauchi, H., Inoue, A., Raimondi, F., Tsujimoto, H., Kusakizako, T., Shihoya, W., Yamashita, K., Suno, R., Nomura, N., Kobayashi, T., Iwata, S., Nishizawa, T. and Nureki, O.
- Journal Title
  
  Nat. Struct. Mol. Biol.
  
  Volume: 28 Issue: 8 Pages: 694-701
- DOI
  10.1038/s41594-021-00634-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06294, KAKENHI-PLANNED-21H05112, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-19H03428, KAKENHI-PROJECT-21K19360, KAKENHI-PROJECT-20K15754, KAKENHI-PROJECT-22KJ0604, KAKENHI-PROJECT-21H05037, KAKENHI-PLANNED-19H05777
[Journal Article] Capturing structural changes of the S1 to S2 transition of photosystem II using time-resolved serial femtosecond crystallography2021
- Author(s)
  H Li, Y Nakajima, T Nomura, M Sugahara, S Yonekura, SK Chan, T Nakane, T Yamane, Y Umena, M Suzuki, T Masuda, T Motomura, H Naitow, Y Matsuura, T Kimura, K Tono, S Owada, Y Joti, R Tanaka, E Nango, F Akita, M Kubo, S Iwata, JR Shen and M Suga
- Journal Title
  
  IUCrJ
  
  Volume: 8 Issue: 3 Pages: 431-443
- DOI
  10.1107/s2052252521002177
- NAID
  120007037379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05446, KAKENHI-PROJECT-18K06158, KAKENHI-ORGANIZER-17H06433, KAKENHI-PLANNED-19H05781, KAKENHI-PLANNED-19H05784, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-20H03226, KAKENHI-PROJECT-20K06238, KAKENHI-PLANNED-17H06434, KAKENHI-PLANNED-19H05777
[Journal Article] Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein.2021
- Author(s)
  Nojima S, Fujita Y, Kimura KT, Nomura N, Suno R, Morimoto K, Yamamoto M, Noda T, Iwata S, Shigematsu H, Kobayashi T.
- Journal Title
  
  Structure
  
  Volume: 29 Issue: 3 Pages: 252-260
- DOI
  10.1016/j.str.2020.11.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-19H03428, KAKENHI-PROJECT-19J12880, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06172, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-20H03434
[Journal Article] Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin2021
- Author(s)
  Oda Kazumasa、Nomura Takashi、Nakane Takanori、Yamashita Keitaro、Inoue Keiichi、Ito Shota、Vierock Johannes、Hirata Kunio、Maturana Andres D、Katayama Kota、( 32 authers )、Kandori Hideki、Hegemann Peter、Iwata So、Kubo Minoru、Nishizawa Tomohiro、Nureki Osamu
- Journal Title
  
  eLife
  
  Volume: 10 Pages: 1-21
- DOI
  10.7554/elife.62389
- NAID
  120006996980
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21251, KAKENHI-PROJECT-20K21383, KAKENHI-PROJECT-20K21392, KAKENHI-PROJECT-20K15754, KAKENHI-PUBLICLY-19H04959, KAKENHI-PLANNED-19H05784, KAKENHI-PUBLICLY-20H05098, KAKENHI-PUBLICLY-20H05441, KAKENHI-PLANNED-20H05758, KAKENHI-PROJECT-18H03986, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-17H03007, KAKENHI-PROJECT-19H03195, KAKENHI-PROJECT-18J21256, KAKENHI-PROJECT-16H06294, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-20H03200, KAKENHI-PROJECT-21H02414
[Journal Article] Structural insights into tetraspanin CD9 function2020
- Author(s)
  Umeda Rie、Satouh Yuhkoh、Takemoto Mizuki、Nakada-Nakura Yoshiko、Liu Kehong、Yokoyama Takeshi、Shirouzu Mikako、Iwata So、Nomura Norimichi、Sato Ken、Ikawa Masahito、Nishizawa Tomohiro、Nureki Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 643-651
- DOI
  10.1038/s41467-020-15459-7
- NAID
  120006957458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06686, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-16H06294, KAKENHI-PLANNED-19H05777, KAKENHI-PLANNED-19H05711
[Journal Article] The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone2020
- Author(s)
  Asada Hidetsugu、Inoue Asuka、Ngako Kadji Francois Marie、Hirata Kunio、Shiimura Yuki、Im Dohyun、Shimamura Tatsuro、Nomura Norimichi、Iwanari Hiroko、Hamakubo Takao、Kusano-Arai Osamu、Hisano Hiromi、Uemura Tomoko、Suno Chiyo、Aoki Junken、Iwata So
- Journal Title
  
  Structure
  
  Volume: 28 Issue: 4 Pages: 418-425.e4
- DOI
  10.1016/j.str.2019.12.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K16217, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] The Intervening Removable Affinity Tag (iRAT) System for the Production of Recombinant Antibody Fragments2020
- Author(s)
  Nomura Norimichi、Nomura Yayoi、Sato Yumi、Iwata So
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 2247 Pages: 77-103
- DOI
  10.1007/978-1-0716-1126-5_5
- ISBN
  9781071611258, 9781071611265
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05777
[Journal Article] Isolation and thermal stabilization of mouse ferroportin2020
- Author(s)
  Deshpande Chandrika N.、Azucenas Corbin R.、Qiao Bo、Nomura Norimichi、Xin Vicky、Font Josep、Iwata So、Ganz Tomas、Nemeth Elizabeta、Mackenzie Bryan、Jormakka Mika
- Journal Title
  
  FEBS Open Bio
  
  Volume: 11 Issue: 1 Pages: 26-34
- DOI
  10.1002/2211-5463.13039
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PLANNED-19H05777
[Journal Article] Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone2020
- Author(s)
  Im Dohyun、Inoue Asuka、Fujiwara Takaaki、Nakane Takanori、Yamanaka Yasuaki、Uemura Tomoko、Mori Chihiro、Shiimura Yuki、Kimura Kanako Terakado、Asada Hidetsugu、Nomura Norimichi、Tanaka Tomoyuki、Yamashita Ayumi、Nango Eriko、Tono Kensuke、Kadji Francois Marie Ngako、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41467-020-20221-0
- NAID
  120006943309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21392, KAKENHI-PLANNED-19H05781, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02394, KAKENHI-PROJECT-18K05334, KAKENHI-ORGANIZER-19H05776, KAKENHI-PLANNED-19H05777, KAKENHI-PROJECT-18H02388
[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020
- Author(s)
  Matoba Kazuaki、Kotani Tetsuya、Tsutsumi Akihisa、Tsuji Takuma、Mori Takaharu、Noshiro Daisuke、Sugita Yuji、Nomura Norimichi、Iwata So、Ohsumi Yoshinori、Fujimoto Toyoshi、Nakatogawa Hitoshi、Kikkawa Masahide、Noda Nobuo N.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 27 Issue: 12 Pages: 1185-1193
- DOI
  10.1038/s41594-020-00518-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06532, KAKENHI-PROJECT-19K07265, KAKENHI-PROJECT-19K16071, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H05339, KAKENHI-PROJECT-16H06375, KAKENHI-PROJECT-19H05645, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06097, KAKENHI-PLANNED-19H05708, KAKENHI-PLANNED-19H05777
[Journal Article] Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine2019
- Author(s)
  Kimura Kanako Terakado、Asada Hidetsugu、Inoue Asuka、Kadji Francois Marie Ngako、Im Dohyun、Mori Chihiro、Arakawa Takatoshi、Hirata Kunio、Nomura Yayoi、Nomura Norimichi、Aoki Junken、Iwata So、Shimamura Tatsuro
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 26 Issue: 2 Pages: 121-128
- DOI
  10.1038/s41594-018-0180-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388, KAKENHI-PROJECT-19H00923, KAKENHI-PLANNED-19H05777
[Journal Article] FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics2019
- Author(s)
  Kinjo Tomoaki、Terai Kenta、Horita Shoichiro、Nomura Norimichi、Sumiyama Kenta、Togashi Kaori、Iwata So、Matsuda Michiyuki
- Journal Title
  
  Nature Methods
  
  Volume: 16 Issue: 10 Pages: 1029-1036
- DOI
  10.1038/s41592-019-0541-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K07066, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18H02490, KAKENHI-PROJECT-17J07950, KAKENHI-PROJECT-16H06280, KAKENHI-PLANNED-19H05777
[Journal Article] Outward open conformation of a Major Facilitator Superfamily multidrug/H+ antiporter provides insights into switching mechanism2018
- Author(s)
  Nagarathinam K, Nakada-Nakura Y, Parthier C, Terada T, Juge N, Jaenecke F, Liu K, Hotta Y, Miyaji T, Omote H, Iwata S, Nomura N, Stubbs M, Tanabe M
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4005-4005
- DOI
  10.1038/s41467-018-06306-x
- NAID
  120006528362
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06114, KAKENHI-PROJECT-17K19489, KAKENHI-PROJECT-18H03179
[Journal Article] Structural basis for tumor necrosis factor blockade with the therapeutic antibody golimumab2018
- Author(s)
  Ono Masatsugu、Horita Shoichiro、Sato Yumi、Nomura Yayoi、Iwata So、Nomura Norimichi
- Journal Title
  
  Protein Science
  
  Volume: 印刷中 Issue: 6 Pages: 1038-1046
- DOI
  10.1002/pro.3407
- NAID
  120006471155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PROJECT-18K05334
[Journal Article] Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog2018
- Author(s)
  Asada H, Horita S, Hirata K, Shiroishi M, Shiimura Y, Iwanari H, Hamakubo T, Shimamura T, Nomura N, Kusano-Arai O, Uemura T, Suno C, Kobayashi T, Iwata S.
- Journal Title
  
  Nature Structural and Molecular Biology
  
  Volume: 25 Issue: 7 Pages: 570-576
- DOI
  10.1038/s41594-018-0079-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-17K19349, KAKENHI-PROJECT-18H02388
[Journal Article] The multidrug-resistance transporter MdfA from Escherichia coli: crystallization and X-ray diffraction analysis2017
- Author(s)
  Nagarathinam Kumar、Jaenecke Frank、Nakada-Nakura Yoshiko、Hotta Yunhon、Liu Kehong、Iwata So、Stubbs Milton T.、Nomura Norimichi、Tanabe Mikio
- Journal Title
  
  Acta Crystallographica Section F Structural Biology Communications
  
  Volume: 73 Issue: 7 Pages: 423-430
- DOI
  10.1107/s2053230x17008500
- NAID
  120006318883
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] The intervening removable affinity tag (iRAT) production system facilitates Fv antibody fragment-mediated crystallography.2016
- Author(s)
  Nomura Y, Sato Y, Suno R, Horita S, Iwata S, Nomura N.
- Journal Title
  
  Protein Sci.
  
  Volume: 25 Issue: 12 Pages: 2268-2276
- DOI
  10.1002/pro.3035
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J04343, KAKENHI-PROJECT-15K06968, KAKENHI-PROJECT-15K08268
[Journal Article] A three dimensional movie of structural changes in bacteriorhodopsin.2016
- Author(s)
  Nango, E., Royant, A.†, Kubo, M.† et al. (†equal contribution)(45名中2番目)
- Journal Title
  
  Science
  
  Volume: 354 Issue: 6319 Pages: 1552-1557
- DOI
  10.1126/science.aah3497
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01055, KAKENHI-PROJECT-15H03841, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15H05476, KAKENHI-PROJECT-15K18486, KAKENHI-PROJECT-15K18523, KAKENHI-PROJECT-16H06315
[Journal Article] High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1.2016
- Author(s)
  Horita S, Nomura Y, Sato Y, Shimamura T, Iwata S, Nomura N.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 35297-35297
- DOI
  10.1038/srep35297
- NAID
  120005850219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-15J04343, KAKENHI-PROJECT-15K06968
[Journal Article] Structure and Molecular Mechanism of the Mammalian Fructose Transporter GLUT52016
- Author(s)
  野村紀通，岩田想
- Journal Title
  
  Nihon Kessho Gakkaishi
  
  Volume: 58 Issue: 3 Pages: 133-138
- DOI
  10.5940/jcrsj.58.133
- NAID
  130005159764
- ISSN
  0369-4585, 1884-5576
- Language
  Japanese
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06968
[Journal Article] Structure and mechanism of the mammalian fructose transporter GLUT52015
- Author(s)
  Nomura N, Verdon G, Kang HJ, Shimamura T, Nomura Y, Sonoda Y, Hussien SA, Qureshi AA, Coincon M, Sato Y, Abe H, Nakada-Nakura Y, Hino T, Arakawa T, Kusano-Arai O, Iwanari H, Murata T, Kobayashi T, Hamakubo T, Kasahara M, Iwata S, Drew D
- Journal Title
  
  Nature
  
  Volume: 526 Issue: 7573 Pages: 397-401
- DOI
  10.1038/nature14909
- NAID
  120005657713
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06968, KAKENHI-PLANNED-24108007, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-25711004
[Journal Article] Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharoroyces cerevisiae.2012
- Author(s)
  Shiroishi M., et al.
- Journal Title
  
  Micorb, Cell Fact.
  
  Volume: 11 Issue: 1 Pages: 78-78
- DOI
  10.1186/1475-2859-11-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074, KAKENHI-PROJECT-23770123, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PUBLICLY-24121715
[Journal Article] G protein-coupled receptor inactivation by an allosteric inverse-agonist antibody2012
- Author(s)
  Hino T., et al
- Journal Title
  
  Nature
  
  Volume: 482 Issue: 7384 Pages: 237-40
- DOI
  10.1038/nature10750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-20221010, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074
[Journal Article] Cloning, expressionand purification of the anion exchanger 1homologue from basidiomycetePhanerochaete chrysosporium2011
- Author(s)
  Tokuda, N., Igarashi, K., Shimamura, T., Yurugi-Kobayashi, T., Shiroishi, M., Ito, K., Sugawara, T., Asada, H., Murata, T., Nomura, N., Iwata, S. and Kobayashi, T.
- Journal Title
  
  Protein Expr. Purif
  
  Volume: 79 Pages: 81-87
- URL
  http://www.sciencedirect.com/science/article/pii/S1046592811000866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659059
[Journal Article] Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T., Iwata, S., Kobayashi, T
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 10 Issue: 1 Pages: 24-24
- DOI
  10.1186/1475-2859-10-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04341, KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium2011
- Author(s)
  Tokuda N, Igarashi K, Shimamura T(co-1st author), Yurugi-Kobayashi T, Shiroishi M, Ito K, Sugawara T, Asada H, Murata T, Nomura N, Iwata S, Kobayashi T.
- Journal Title
  
  Protein. Expr. Purif.
  
  Volume: 79(1) Issue: 1 Pages: 81-7
- DOI
  10.1016/j.pep.2011.04.006
- NAID
  120003255719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23657074
[Journal Article] Evaluation of the Pichiapastoris expression system for theproduction of GPCRs for structuralanalysis2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T. Iwata, S. and Kobayashi, T.
- Journal Title
  
  Microb. Cell Fact
  
  Volume: 10 Pages: 24-24
- URL
  http://www.microbialcellfactories.com/content/10/1/24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659059
[Journal Article] Structure of a hyperthermophilic archaeal homing endonuclease, I-Tsp 0611 : Contribution of cross-domain polar networks to thermostability2007
- Author(s)
  Nakayama, H., T., Shimamura, T., Imagawa, N., Shirai, T., Itoh, Y., Sako, M., Miyano, H., Sakuraba, T., Oshima, N., Nomura, H., Tanga
- Journal Title
  
  J. Mol. Biol 365
  
  Pages: 362-378
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208020
[Journal Article] I-Apel : a novel intron-encoded LAGLIDADG homing endonuclease from the archaea, Aeropyrum @ernix K1.2005
- Author(s)
  Nomura N. et al.
- Journal Title
  
  Nucleic Acid Res. 33
- Data Source
  KAKENHI-PROJECT-16208020
[Patent] 皮膚筋炎又は間質性肺炎の患者の治療抵抗性の予測方法、及び当該方法に使用されるキット2024
- Inventor(s)
  笹井蘭、笹井恒雄、野中元裕、野村紀通
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-015255
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-19H00923
[Patent] 皮膚筋炎又は間質性肺炎の患者の治療抵抗性の予測方法、及び当該方法に使用されるキット2024
- Inventor(s)
  笹井蘭、笹井恒雄、野中元裕、野村紀通
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-015255
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K27415
[Patent] 皮膚筋炎又は間質性肺炎の患者の治療抵抗性の予測方法、及び当該方法に使用されるキット2024
- Inventor(s)
  笹井蘭、笹井恒雄、野中元裕、野村紀通
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-015255
- Filing Date
  2024
- Data Source
  KAKENHI-PLANNED-19H05777
[Patent] 皮膚筋炎又は間質性肺炎の患者の治療抵抗性の予測方法、及び当該方法に使用されるキット2024
- Inventor(s)
  笹井蘭、笹井恒雄、野中元裕、野村紀通
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-015255
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K18239
[Patent] 膜蛋白質の立体構造を認識するモノクローナル抗体のスクリーニング方法2010
- Inventor(s)
  岩田想・小林拓也・野村紀通
- Industrial Property Rights Holder
  科学技術振興機構
- Filing Date
  2010
- Overseas
- Data Source
  KAKENHI-PROJECT-22659059
[Patent] 膜蛋白質の立体構造を認識するモノクローナル抗体のスクリーニング方法2010
- Inventor(s)
  日野智也, 村田武士, 荒川孝俊, 野村紀通, 小林拓也, 岩田想
- Industrial Property Rights Holder
  日野智也, 村田武士, 荒川孝俊, 野村紀通, 小林拓也, 岩田想
- Filing Date
  2010-04-28
- Overseas
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 抗体を用いた膜タンパク質構造研究2023
- Author(s)
  野村紀通
- Organizer
  京都大学BINDS合同シンポジウム：オープンイノベーションから創薬へ 2023
- Invited
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2023
- Author(s)
  浅見仁太*、朴在鉉、野村弥生、石本直偉士*、小林ちさ*、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2023
- Author(s)
  浅見仁太*、朴在鉉、野村弥生、石本直偉士*、小林ちさ*、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K27415
[Presentation] 抗体を用いた膜タンパク質構造研究2023
- Author(s)
  野村紀通
- Organizer
  京都大学BINDS合同シンポジウム：オープンイノベーションから創薬へ 2023
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] X線結晶構造解析で見るTNF阻害剤の分子機構2023
- Author(s)
  野村紀通
- Organizer
  潰瘍性大腸炎Webセミナー「TNFα阻害剤をMOAから再考する」
- Invited
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 抗体を用いた膜タンパク質構造研究2023
- Author(s)
  野村紀通
- Organizer
  京都大学BINDS合同シンポジウム：オープンイノベーションから創薬へ 2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K18239
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2023
- Author(s)
  浅見仁太*、朴在鉉、野村弥生、石本直偉士*、小林ちさ*、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-23K18239
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2023
- Author(s)
  浅見仁太*、朴在鉉、野村弥生、石本直偉士*、小林ちさ*、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] 抗体を用いた膜タンパク質構造研究2023
- Author(s)
  野村紀通
- Organizer
  京都大学BINDS合同シンポジウム：オープンイノベーションから創薬へ 2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K27415
[Presentation] 膜タンパク質構造研究この10年2022
- Author(s)
  野村紀通
- Organizer
  京都大学大学院医学研究科医学研究支援センター開設10周年記念セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] Unveiling membrane protein structures with the aid of antibody toolkits2022
- Author(s)
  Norimichi Nomura
- Organizer
  OIST-Kyoto University Joint Workshop -Challenges in Biomedical Complexity-
- Invited
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] X線結晶構造解析で見るTNF阻害剤の分子機構2022
- Author(s)
  野村紀通
- Organizer
  Golimumab Value Creation Seminar
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] Unveiling membrane protein structures with the aid of antibody toolkits2022
- Author(s)
  Norimichi Nomura
- Organizer
  OIST-Kyoto University Joint Workshop -Challenges in Biomedical Complexity-
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] Structural analysis of the hepatitis B virus entry receptor NTCP2022
- Author(s)
  浅見仁太、木村香菜子、藤田陽子、石田英子、張志寛、野村弥生、劉紅、植村智子、佐藤有美、小野真嗣、山本雅貴、野田岳志、重松秀樹、ドリューデイビッド、岩田想、清水敏之、野村紀通、大戸梅治
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] X線結晶構造解析で見るTNF阻害剤の分子機構2022
- Author(s)
  野村紀通
- Organizer
  TNF Value Creation Seminar
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] 膜タンパク質構造研究この10年2022
- Author(s)
  野村紀通
- Organizer
  京都大学大学院医学研究科医学研究支援センター開設10周年記念セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 胆汁酸トランスポーターNTCPを介したB型肝炎ウイルスの侵入に関する構造的洞察2022
- Author(s)
  木村香菜子、浅見仁太、藤田陽子、石田英子、張志寛、野村弥生、劉紅、植村智子、佐藤有美、小野真嗣、山本雅貴、野田岳志、重松秀樹、Drew David、岩田想、清水敏之、野村紀通、大戸梅治
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] 胆汁酸トランスポーターNTCPによるB型肝炎ウイルス認識の構造基盤2022
- Author(s)
  浅見仁太、朴在鉉、野村弥生、石本直偉士、小林ちさ、御舩淳紀、植村智子、劉紅、佐藤有美、村松正道、脇田隆字、Drew David、渡士幸一、岩田想、清水敏之、朴三用、野村紀通、大戸梅治
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] B型肝炎ウイルス受容体NTCPの構造解析2022
- Author(s)
  浅見仁太、木村香菜子、藤田陽子、石田英子、張志寛、野村弥生、劉紅、植村智子、佐藤有美、小野真嗣、山本雅貴、野田岳志、重松秀樹、Drew David、岩田想、清水敏之、野村紀通、大戸梅治
- Organizer
  日本薬学会第142年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] B型肝炎ウイルス受容体NTCPの構造解析2022
- Author(s)
  浅見仁太、木村香菜子、藤田陽子、石田英子、張志寛、野村弥生、劉紅、植村智子、佐藤有美、小野真嗣、山本雅貴、野田岳志、重松秀樹、Drew David、岩田想、清水敏之、野村紀通、大戸梅治
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 次世代構造創薬研究を先導するヒト膜タンパク質・抗体の生産技術支援2019
- Author(s)
  岩田　想、野村紀通
- Organizer
  BINDS公開シンポジウム2019
- Data Source
  KAKENHI-PLANNED-19H05777
[Presentation] 次世代構造創薬研究を先導するヒト膜タンパク質・抗体の生産技術支援2019
- Author(s)
  岩田想，野村紀通
- Organizer
  BINDS公開シンポジウム2019
- Data Source
  KAKENHI-PROJECT-19H00923
[Presentation] 膜蛋白質のX線結晶構造解析を支援する抗体工学技術の確立2011
- Author(s)
  野村紀通, ら
- Organizer
  第84回日本生化学会大会シンポジウム「多様な生物種における膜タンパク質の機能理解を目指した新戦略」
- Place of Presentation
  京都国際会館
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 膜蛋白質のX線結晶構造解析を支援する抗体工学技術の確立2011
- Author(s)
  野村紀通,他
- Organizer
  第84回日本生化学会大会シンポジウム「多様な生物種における膜タンパク質の機能理解を目指した新戦略」
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 抗体フラグメントを用いたヒト膜タンパク質の結晶構造解析2010
- Author(s)
  岩田想, 野村紀通
- Organizer
  BioJapan2014アカデミックシーズ発表会
- Place of Presentation
  パシフィコ横浜(横浜市西区)
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-22570114
[Presentation] 好気性超好熱菌Aeropyrum pernixTB5株由来ヒドロゲナーゼの精製と性状解析2007
- Author(s)
  西村宏・岩田恵里・野村良子・左子芳彦
- Organizer
  日本水産学会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16208020
[Presentation] 好気性超好熱菌Aeropyrum pernix TB5株由来ヒドロゲナーゼの精製と性状解析2007
- Author(s)
  西村宏・岩田恵里・野村良子・左子芳彦
- Organizer
  日本水産学会
- Place of Presentation
  東京海洋大学
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-16208020
[Presentation] Purification and characterization of hydrogenase from aerobic hyperther- mophilic archaeon Aaropyrum pernix TB52007
- Author(s)
  Nishimura, H., E., Iwata, Y., Nomura, Y., Sako
- Organizer
  The Japanese Society of Fisheries Scince
- Place of Presentation
  Tokyo Univ. of Marine Science and Technology, Tokyo
- Year and Date
  2007-03-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16208020

1. IWATA So (60452330)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. SAKO Yoshihiko (60153970)

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28. IM Dohyun

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42. 森貴治

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43. 井上明俊

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Nomura Norimichi 野村 紀通

NOMURA Norimichi 野村 紀通

NOMURA Norimiti 野村 紀通

Research Projects

Research Products

Co-Researchers

ウイルス膜蛋白質の生理的準安定構造の解明と創薬応用Principal Investigator

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Structural biology of the hepatitis B virus entry and its inhibitionPrincipal Investigator

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テトラスパニンを介した新たながん転移促進機構の解明Principal Investigator

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Creation and crystallographic studies of artificial medium-sized aptamers that modulate membrane protein functionsPrincipal Investigator

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Crystallographic study of the mammalian bile acid transporter NTCP in complex with its conformation-specific antibodiesPrincipal Investigator

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Technologicaldevelopment for construction of synthetic proteins that facilitate membrane protein crystallizationPrincipal Investigator

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Nomura Norimichi 野村紀通

NOMURA Norimichi 野村紀通

NOMURA Norimiti 野村紀通