UENO TAKAMASA 上野貴将

… Alternative Names

UENO Takamasa 上野貴将

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Researcher Number	10322314
Other IDs	https://orcid.org/0000-0003-4852-4236
External Links
Affiliation (Current)	2024: 熊本大学, ヒトレトロウイルス学共同研究センター, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 熊本大学, ヒトレトロウイルス学共同研究センター, 教授 2018: 熊本大学, エイズ学研究センター, 教授 2016 – 2017: 熊本大学, エイズ学研究センター, 准教授 2014: 熊本大学, 学内共同利用施設等, 准教授 2007 – 2014: Kumamoto University, エイズ学研究センター, 准教授 … More 2012: 熊本大学, 学内共同利用施設等, 准教授 2004 – 2006: 熊本大学, エイズ学研究センター, 講師 2001 – 2003: 熊本大学, エイズ学研究センター, 助手 Less
Review Section/Research Field	Principal Investigator Virology / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 54030:Infectious disease medicine-related / Biological Sciences / Virology / Biological Sciences Except Principal Investigator Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Infectious disease medicine
Keywords	Principal Investigator HIV / HIV/AIDS / 細胞傷害性T細胞 / 感染症 / ウイルス / HLA / HIV感染症 / ワクチン / 抗原提示 / T細胞レセプター … More / 細胞障害性T細胞 / AIDS / 免疫学 / SARS-CoV-2 / HIV-1 / 進化 / 感染防御 / HLAクラスI / 新型コロナウイルス / COVID-19 / 治療脱落者 / HIV-1/AIDS / 中和抗体 / Tanzania / neutralizing antibody / エイズウイルス / 薬剤耐性変異 / ゲノム / ウィルス / タンザニア / 潜伏感染 / プロウイルス / Sub-Sahara Africa / antiviral activity / AID S / T cell receptor / T lymphocyte / Antigen / ファージディスプレイ / 抗体 / MHCクラスI / 抗ウイルス機能 / T細胞 / 抗原 / SURFACE PLASMON RESONANCE / RECOMBINANT PROTEIN / CELLULAR IMMUNITY / CYTOTOXIC T LYMPHOCYTE / ANTIGEN PRESENTATION / T CELL RECEPTOR / 組換え蛋白質 / 表面プラズモン共鳴 / 組替え蛋白質 / 細胞性免疫 / 発現抑制 / Ｎｅｆ / ＨＩＶ／ＡＩＤＳ / ＨＬＡ / 免疫回避 / ＨＩＶ / 抗原ペプチド / 抗ウイルス免疫応答 / 淘汰圧 / 安定性 / Nef / エスケープ / 免疫監視 / ヒト抗ウイルス免疫監視 / 臨床 / 細胞・組織 … More Except Principal Investigator HTLV-1感染症 / 国際共同研究 / HTLV-1 / HIV / アクセサリータンパク / スクリーニング / 免疫淘汰 / 抗ウイルス剤 / ＨＩＶ / Nef / HLAクラスI免疫逃避 / HIV-1細胞障害性T細胞 / 免疫学 / 感染症 / ウイルス Less

Impact of cross-reactive immunity to pre-existing infections on COVID-19 pathogenesis in East AfricaPrincipal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kumamoto University
Investigation for potential CTL epitopes spanning various coronavirues aiming for universal vaccine developmentPrincipal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Tracking of defaulters from HIV treatment programs in developing countriesPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kumamoto University
Identification of broadly neutralizing antibodies to HIV-1 and its correlates with host genetic factorsPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kumamoto University
Molecular epidemiological study of vertically transmitted HIV positive young adultsPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Kumamoto University
Dynamic evolution and different pathogenesis of HTLV-1 across multiple continents revealed by next generation sequencing technology
- Principal Investigator
  
  Satou Yorifumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kumamoto University
Reinvestigating HIV-specific effector cells targeting latent reservoir cellsPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Analysis of latently infected HIV-1 circulating in Sub-Sahara AfricaPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
抗原変異の著しい病原体に対するＨＬＡ分子システムの可塑性と脆弱性Principal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Development of anti-HIV agents that exert synergism with host immune pressure
- Principal Investigator
  
  KODAMA Eiichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tohoku University
A bioinformatics approach toward understanding interplay betweenchronic virus infections and human antiviral immune responsesPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Functional adaptation of HIV accessory proteins towardimmune-mediated selective pressurePrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
CTLの抗ウイルス機能におけるβ2ミクログロブリンの役割Principal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
Effects of HLA alleles on antiviral activity of T cellsPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
ヒト記憶型T細胞のレパートリーが免疫監視機能とその維持に与える影響Principal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Effects of HLA-antigen presentation machinery on the antiviral effectiveness of T lymphocytes.Principal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
ヒト記憶型T細胞のレパートリーが免疫監視機能に及ぼす影響の解明Principal Investigator
- Principal Investigator
  
  上野貴将
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
HIV-1の細胞傷害性T細胞からの逃避機序の研究
- Principal Investigator
  
  滝口雅文
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
HIV-1の細胞傷害性T細胞からの逃避機序の研究
- Principal Investigator
  
  TAKIGUCHI Masafumi
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
KINETIC ANALYSIS OF ANTIGEN-PRESENTATION OF HIV-INFECTED CELLS USING SOLUBLE T CELL RECEPTORSPrincipal Investigator
- Principal Investigator
  
  UENO Takamasa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  KUMAMOTO UNIVERSITY

[Book] HIV感染症-宿主側の防衛因子の役割-「HIVコントロールにおけるCTLの役割」血液フロンティア2008
- Author(s)
  上野貴将、本園千尋
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-19590479
[Book] アイソトープのヒト免疫研究への活用細胞工学別冊実験プロトコールシリーズ2007
- Author(s)
  上野貴将
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Neutralizing immunity against coronaviruses in Tanzanian health care workers2024
- Author(s)
  Barabona Godfrey et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 00-00
- DOI
  10.1038/s41598-024-55989-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K20041, KAKENHI-PROJECT-22KK0148, KAKENHI-PROJECT-23K24378
[Journal Article] Differential Ability of Spike Protein of SARS-CoV-2 Variants to Downregulate ACE22024
- Author(s)
  Maeda Yosuke、Toyoda Mako、Kuwata Takeo、Terasawa Hiromi、Tokugawa Umiru、Monde Kazuaki、Sawa Tomohiro、Ueno Takamasa、Matsushita Shuzo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 2 Pages: 1353-1353
- DOI
  10.3390/ijms25021353
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08602, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-23K24378
[Journal Article] Evaluation of Neutralizing Activity against Omicron Subvariants in BA.5 Breakthrough Infection and Three-Dose Vaccination Using a Novel Chemiluminescence-Based, Virus-Mediated Cytopathic Assay2023
- Author(s)
  Toyoda Mako、Tan Toong Seng、Motozono Chihiro、Barabona Godfrey、Yonekawa Akiko、Shimono Nobuyuki、Minami Rumi、Nagasaki Yoji、Miyashita Yusuke、Oshiumi Hiroyuki、Nakamura Kimitoshi、Matsushita Shuzo、Kuwata Takeo、Ueno Takamasa
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 11 Issue: 4 Pages: 00660-23
- DOI
  10.1128/spectrum.00660-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1775, KAKENHI-PROJECT-22KK0277, KAKENHI-PROJECT-22K07089, KAKENHI-PROJECT-21K05989, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-23K24139, KAKENHI-PROJECT-23K24378, KAKENHI-PROJECT-23K27640
[Journal Article] Hypertension and traditional risk factors for cardiovascular diseases among treatment na?ve HIV- infected adults initiating antiretroviral therapy in Urban Tanzania2023
- Author(s)
  Mwakyandile Tosi M.、Shayo Grace A.、Sasi Philip G.、Mugusi Ferdinand M.、Barabona Godfrey、Ueno Takamasa、Lyamuya Eligius F.
- Journal Title
  
  BMC Cardiovascular Disorders
  
  Volume: 23 Issue: 1 Pages: 309-309
- DOI
  10.1186/s12872-023-03332-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0148
[Journal Article] Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates2023
- Author(s)
  Matsumoto Kaho、Kuwata Takeo、Tolbert William D.、Richard Jonathan、Ding Shilei、Prevost Jeremie、Takahama Shokichi、Judicate George P.、Ueno Takamasa、Nakata Hirotomo、Kobayakawa Takuya、Tsuji Kohei、Tamamura Hirokazu、Smith Amos B.、Pazgier Marzena、Finzi Andres、Matsushita Shuzo
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 1
- DOI
  10.1128/jvi.01638-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05989, KAKENHI-PROJECT-22K15243, KAKENHI-PROJECT-20H03362, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-21K19657
[Journal Article] HIV virologic response, patterns of drug resistance mutations and correlates among adolescents and young adults: A cross-sectional study in Tanzania2023
- Author(s)
  Rugemalila J, Kamori D, Kunambi P, Mizinduko M. Sabasaba A. Masoud S, Msafiri F, Mugusi S. Mutagonda R. Mlunde L, Amani D, Mboya E. Mahiti M. Ruhago G. Mushi J. Sambu V, Mgomella G, Jullu B, Maokola W, Njau P, Mutayoba B, Barabona G, Ueno T, Pembe A. Nagu T. Sunguya B. Aboud S.
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 2 Pages: e0281528-e0281528
- DOI
  10.1371/journal.pone.0281528
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19657, KAKENHI-PROJECT-22KK0148
[Journal Article] Emerging integrase strand transfer inhibitor drug resistance mutations among children and adults on ART in Tanzania: findings from a national representative HIV drug resistance survey2023
- Author(s)
  Kamori D, Barabona G, Rugemalila J. Maokola W. Masoud S. Mizinduko M. Ruhago G. Sambu V, Mushi J. Mgomella G, Mcollogi J, Msafiri F, Mugusi S, Boniface J, Mutagonda R, Mlunde L. Amani D, Mboya E, Mahiti M, Rwebembera A, Ueno T, Pembe A. Njau P. Mutayoba B. Sunguya B
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: 78 Issue: 3 Pages: 779-787
- DOI
  10.1093/jac/dkad010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19657, KAKENHI-PROJECT-22KK0148
[Journal Article] Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-192022
- Author(s)
  Ogura Hideki、Gohda Jin、Lu Xiuyuan、Yamamoto Mizuki、Takesue Yoshio、Son Aoi、Doi Sadayuki、Matsushita Kazuyuki、Isobe Fumitaka、Fukuda Yoshihiro、Huang Tai-Ping、Ueno Takamasa、Mambo Naomi、Murakami Hiromoto、Kawaguchi Yasushi、Inoue Jun-ichiro、Shirai Kunihiro、Yamasaki Sho、Hirata Jun-Ichi、Ishido Satoshi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7063-7063
- DOI
  10.1038/s41467-022-34655-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0148, KAKENHI-PLANNED-22H05183, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20K07610, KAKENHI-PROJECT-23K24378
[Journal Article] The SARS-CoV-2 Omicron BA.1 spike G446S mutation potentiates antiviral T-cell recognition2022
- Author(s)
  Motozono C, Toyoda M, Tan TS, Hamana H, Goto Y, Aritsu Y, Miyashita Y, Oshiumi H, Nakamura K, Okada S, Udaka K, Kitamatsu M, Kishi H, Ueno T
- Journal Title
  
  Nat Commun
  
  Volume: 13 Issue: 1 Pages: 5440-5440
- DOI
  10.1038/s41467-022-33068-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-22KK0148, KAKENHI-PROJECT-21H02966, KAKENHI-PROJECT-23K24139, KAKENHI-PROJECT-23K24378
[Journal Article] Dissecting Naturally Arising Amino Acid Substitutions at Position L452 of SARS-CoV-2 Spike2022
- Author(s)
  Tan Toong Seng、Toyoda Mako、Ode Hirotaka、Barabona Godfrey、Hamana Hiroshi、Kitamatsu Mizuki、Kishi Hiroyuki、Motozono Chihiro、Iwatani Yasumasa、Ueno Takamasa
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 20
- DOI
  10.1128/jvi.01162-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0148, KAKENHI-PROJECT-21H02966, KAKENHI-PROJECT-23K24139, KAKENHI-PROJECT-23K24144, KAKENHI-PROJECT-23K24378
[Journal Article] Advanced baseline immunosuppression is associated with elevated levels of plasma markers of fungal translocation and inflammation in long-term treated HIV-infected Tanzanians2021
- Author(s)
  Barabona Godfrey、Mahiti Macdonald、Toyoda Mako、Kamori Doreen、Masoud Salim、Judicate George P.、Sunguya Bruno、Lyamuya Eligius、Ueno Takamasa
- Journal Title
  
  AIDS Research and Therapy
  
  Volume: 18 Issue: 1
- DOI
  10.1186/s12981-021-00381-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21K19657
[Journal Article] SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity2021
- Author(s)
  Ozono Seiya、Zhang Yanzhao、Ode Hirotaka、Sano Kaori、Tan Toong Seng、Imai Kazuo、Miyoshi Kazuyasu、Kishigami Satoshi、Ueno Takamasa、Iwatani Yasumasa、Suzuki Tadaki、Tokunaga Kenzo
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 848-848
- DOI
  10.1038/s41467-021-21118-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03482, KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-18K07156
[Journal Article] Acquired HIV drug resistance among children and adults receiving antiretroviral therapy in Tanzania: a national representative survey protocol2021
- Author(s)
  Rugemalila Joan、Kamori Doreen、Maokola Werner、Mizinduko Mucho、Barabona Godfrey、Masoud Salim、Mlunde Linda B、Mutagonda Ritah Francis、Ruhago George、Mushi Jeremiah、Sambu Veryeh、Ueno Takamasa、Mutayoba Beatrice、Njau Prosper、Nagu Tumaini、Aboud Said、Sunguya Bruno F
- Journal Title
  
  BMJ Open
  
  Volume: 11 Issue: 12 Pages: e054021-e054021
- DOI
  10.1136/bmjopen-2021-054021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21K19657
[Journal Article] Seroprevalence of Human Herpesvirus Infections in Newly Diagnosed HIV-Infected Key Populations in Dar es Salaam, Tanzania2021
- Author(s)
  Kamori Doreen、Joachim Agricola、Mizinduko Mucho、Barabona Godfrey、Mahiti Macdonald、Kibwana Upendo、Majigo Mtebe、Masoud Salim、Mwandigha Ambele M.、Ueno Takamasa、Mmbaga Elia、Lyamuya Eligius
- Journal Title
  
  International Journal of Microbiology
  
  Volume: 2021 Pages: 1-7
- DOI
  10.1155/2021/4608549
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21K19657
[Journal Article] Impact of Human Leukocyte Antigen-Associated Polymorphisms on Variability of HIV-1 Accessory and Regulatory Proteins2021
- Author(s)
  Kamori Doreen、Hasan Zafrul、Carlson Jonathan、Kawana-Tachikawa Ai、Gatanaga Hiroyuki、Oka Shinichi、Ueno Takamasa
- Journal Title
  
  AIDS Research and Human Retroviruses
  
  Volume: - Issue: 12 Pages: 962-966
- DOI
  10.1089/aid.2021.0055
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0230, KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21K19657
[Journal Article] Aromatic Side Chain at Position 412 of SERINC5 Exerts Restriction Activity toward HIV-1 and Other Retroviruses2021
- Author(s)
  Tan Toong Seng、Toyoda Mako、Tokunaga Kenzo、Ueno Takamasa
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 18
- DOI
  10.1128/jvi.00634-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21K07060
[Journal Article] Phenotypic and Genotypic Co-receptor Tropism Testing in HIV-1 Epidemic Region of Tanzania Where Multiple Non-B Subtypes Co-circulate2021
- Author(s)
  Judicate George P.、Barabona Godfrey、Kamori Doreen、Mahiti Macdonald、Tan Toong Seng、Ozono Seiya、Mgunya Amina Shaban、Kuwata Takeo、Matsushita Shuzo、Sunguya Bruno、Lyamuya Eligius、Tokunaga Kenzo、Ueno Takamasa
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 12 Pages: 703041-703041
- DOI
  10.3389/fmicb.2021.703041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-21H02970, KAKENHI-PROJECT-21K05989, KAKENHI-PROJECT-21K07060, KAKENHI-PROJECT-21K19657
[Journal Article] An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles2020
- Author(s)
  Mwimanzi Francis、Ngare Isaac、Toyoda Mako、Mori Masahiko、Mann Jaclyn、Ndung’u Thumbi、Goulder Phillip、Ueno Takamasa
- Journal Title
  
  AIDS
  
  Volume: 34 Issue: 9 Pages: 1325-1330
- DOI
  10.1097/qad.0000000000002559
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-18K15170, KAKENHI-PROJECT-18KK0230
[Journal Article] Circulating HIV-1 Integrase Genotypes in Tanzania: Implication on the Introduction of Integrase Inhibitors-Based Antiretroviral Therapy Regimen2020
- Author(s)
  Masoud Salim、Kamori Doreen、Barabona Godfrey、Mahiti Macdonald、Sunguya Bruno、Lyamuya Eligius、Ueno Takamasa
- Journal Title
  
  AIDS Research and Human Retroviruses
  
  Volume: - Issue: 6 Pages: 539-543
- DOI
  10.1089/aid.2020.0021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-18K19686, KAKENHI-PROJECT-18K16178, KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-18KK0230
[Journal Article] Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals2020
- Author(s)
  Toyoda Mako、Kamori Doreen、Tan Toong Seng、Goebuchi Kageaki、Ohashi Jun、Carlson Jonathan、Kawana-Tachikawa Ai、Gatanaga Hiroyuki、Oka Shinichi、Pizzato Massimo、Ueno Takamasa
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41598-020-76375-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703, KAKENHI-PROJECT-18K15170
[Journal Article] Modelling and in vitro testing of the HIV-1 Nef fitness landscape2019
- Author(s)
  Barton John P、Rajkoomar Erasha、Mann Jaclyn K、Murakowski Dariusz K、Toyoda Mako、Mahiti Macdonald、Mwimanzi Phillip、Ueno Takamasa、Chakraborty Arup K、Ndung’u Thumbi
- Journal Title
  
  Virus Evolution
  
  Volume: 5 Issue: 2
- DOI
  10.1093/ve/vez029
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19686
[Journal Article] Pre-treatment and acquired HIV drug resistance in Dar es Salaam, Tanzania in the era of tenofovir and routine viral load monitoring2019
- Author(s)
  Barabona Godfrey、Mahiti Macdonald、Masoud Salim、Mbelele Peter、Mgunya Amina Shaban、Minja Lilian、Sunguya Bruno、Shigemi Urara、Matsuda Masakazu、Hachiya Atsuko、Iwatani Yasumasa、Lyamuya Eligius、Ueno Takamasa
- Journal Title
  
  Journal of Antimicrobial Chemotherapy
  
  Volume: 74 Issue: 10 Pages: 3016-3020
- DOI
  10.1093/jac/dkz272
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-19H03482, KAKENHI-PROJECT-18K19686, KAKENHI-PROJECT-18K16178, KAKENHI-PROJECT-19H03703
[Journal Article] Resistance of major histocompatibility complex class B (MHC-B) to Nef-mediated downregulation relative to that of MHC-A is conserved among primate lentiviruses and influences antiviral T cell responses in HIV-1-infected individuals.2018
- Author(s)
  F Mwimanzi, M Toyoda, M Mahiti, J Mann, J Martin, D Bangsberg, M Brockman, P Goulder, F Kirchhoff, Z Brumme, T Ndung’u, T Ueno
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 1
- DOI
  10.1128/jvi.01409-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284, KAKENHI-PROJECT-16K19141, KAKENHI-PROJECT-18K16178
[Journal Article] Single blood transfusion induces the production of donor-specific alloantibodies and regulatory T cells mainly in the spleen.2018
- Author(s)
  Ueta H, Kitazawa Y, Sawanobori Y, Ueno T, Ueha S, Matsushima K, Matsuno K.
- Journal Title
  
  Int Immunol
  
  Volume: 30 Issue: 2 Pages: 53-67
- DOI
  10.1093/intimm/dxx078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08730, KAKENHI-PROJECT-17K08518, KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-15F15113, KAKENHI-PROJECT-16K08474, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05822
[Journal Article] Conserved Vδ1 binding geometry in a setting of locus-disparate pHLA recognition by δ/αβTCRs: insight into recognition of HIV peptides by TCR2017
- Author(s)
  ③Yi Shi, Ai Kawana-Tachikawa, Feng Gao, Jianxun Qi, Chuansheng Liu, Jia Gao, Hao Cheng, Takamasa Ueno, Aikichi Iwamoto, George Gao
- Journal Title
  
  Journal of Virology
  
  Volume: 91
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15284
[Journal Article] HIV-1 Tat and Viral Latency: What We Can Learn from Naturally Occurring Sequence Variations2017
- Author(s)
  Kamori Doreen、Ueno Takamasa
- Journal Title
  
  Frontiers Microbiology
  
  Volume: 8 Pages: 80-80
- DOI
  10.3389/fmicb.2017.00080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284
[Journal Article] Identification of two unique naturally occurring Vpr sequence polymorphisms associated with clinical parameters in HIV-1 chronic infection2017
- Author(s)
  Kamori Doreen、Hasan Zafrul、Ohashi Jun、Kawana-Tachikawa Ai、Gatanaga Hiroyuki、Oka Shinichi、Ueno Takamasa
- Journal Title
  
  Journal of Medical Virology
  
  Volume: 89 Issue: 1 Pages: 123-129
- DOI
  10.1002/jmv.24612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05822, KAKENHI-PROJECT-16K15284
[Journal Article] Relative resistance of HLA-B to down-regulation by naturally occurring HIV-1 Nef sequences2016
- Author(s)
  61.Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D Walker, Yong Xiong, Zabrina L Brumme, Mark A Brockman, Takamasa Ueno
- Journal Title
  
  ｍBio
  
  Volume: 7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822
[Journal Article] Relative resistance of HLA-B to down-regulation by naturally occurring HIV-1 Nef sequences2016
- Author(s)
  Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D Walker, Yong Xiong, Zabrina L Brumme, Mark A Brockman, Takamasa Ueno
- Journal Title
  
  ｍBio
  
  Volume: 7 Issue: 1
- DOI
  10.1128/mbio.01516-15
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15284
[Journal Article] Clonotypically similar hybrid αβ TCRs can exhibit markedly different surface expression, antigen specificity and cross-reactivity.2015
- Author(s)
  Chihiro Motozono, John S. Bridgeman, David A. Price, Andrew K. Sewell ,Takamasa Ueno
- Journal Title
  
  Clinical and Experimental Immunology
  
  Volume: in press Issue: 3 Pages: 560-570
- DOI
  10.1111/cei.12610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma.2015
- Author(s)
  Chen J, Tibroni N, Sauter D, Galaski J, Miura T, Alter G, Mueller B, Haller C, Walker BD, Kirchhoff F, Brumme ZL, Ueno T, Fackler OT.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120434-e0120434
- DOI
  10.1371/journal.pone.0120434
- NAID
  120006987120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Selection of TI8-8V mutant associated with long-term control of HIV-1 by cross-reactive HLA-B*51:01-restricted cytotoxic T cells.2014
- Author(s)
  Nozomi Kuse, Tomohiro Akahoshi, Hiroyuki Gatanaga, Takamasa Ueno, Shinichi Oka, Masafumi Takiguchi
- Journal Title
  
  Journal of Immunology
  
  Volume: 193 Issue: 10 Pages: 4814-4822
- DOI
  10.4049/jimmunol.1401419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Role of host immune responses in sequence variability of HIV-1 Vpu2014
- Author(s)
  Zafrul Hasan, Doreen Kamori and Takamasa Ueno
- Journal Title
  
  World Journal of Immunology
  
  Volume: 4 Issue: 2 Pages: 107-115
- DOI
  10.5411/wji.v4.i2.107
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PUBLICLY-25133706
[Journal Article] Peptide-dependent conformational fluctuation determines the stability of the human leukocyte antigen class Ⅰ complex2014
- Author(s)
  Saeko Yanaka, Takamasa Ueno, Yi Shi, Jianxun Gi, George F. Gao, Kouhei Tsumoto, and Kenji Sugase
- Journal Title
  
  J Biol Chem.
  
  Volume: 268 Issue: 35 Pages: 24680-90
- DOI
  10.1074/jbc.m114.566174
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J09564, KAKENHI-PROJECT-24000011, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25000006, KAKENHI-PUBLICLY-25133706, KAKENHI-PROJECT-25249115
[Journal Article] Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths.2014
- Author(s)
  Chihiro Motozono, Masaru Yokoyama, Hironori Sato, Takamasa Ueno
- Journal Title
  
  Microbes and Infection
  
  Volume: 16 Issue: 4 Pages: 320-327
- DOI
  10.1016/j.micinf.2013.12.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-25133706
[Journal Article] Impaired Nef function is associated with early control of HIV-1 viremia.2014
- Author(s)
  Kuang XT, Li X, Anmole G, Mwimanzi P, Shahid A, Le AQ, Chong L, Qian H, Miura T, Markle T, Baraki B, Connick E, Daar ES, Jessen H, Kelleher AD, Little S, Markowitz M, Pereyra F, Rosenberg ES, Walker BD, Ueno T, Brumme ZL, Brockman MA.
- Journal Title
  
  Journal of Virology
  
  Volume: 88 Issue: 17 Pages: 10200-10213
- DOI
  10.1128/jvi.01334-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PUBLICLY-25133706
[Journal Article] Dynamic range of Nef functionsin chronic HIV-1 infection2013
- Author(s)
  Philip Mwimanzi, Tristan J Markle,Yoko Ogata, Eric Martin, MichiyoTokunaga, Macdonald Mahiti, Xiaomei TKuang, Bruce D Walker, Zabrina L Brumme,Mark A Brockman and *Takamasa Ueno
- Journal Title
  
  Virology
  
  Volume: 439 Issue: 2 Pages: 74-80
- DOI
  10.1016/j.virol.2013.02.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
[Journal Article] CD8+ T cell cross-reactivity profiles and HIV-1 immune escape towards an HLA-B35-restricted immunodominant Nef epitope.2013
- Author(s)
  C. Motozono, J. Miles, Z. Hasan, H. Gatanaga, S. Meribe, D. Price, S. Oka, A. Sewell, T. Ueno
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 6 Pages: e66152-e66152
- DOI
  10.1371/journal.pone.0066152
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25133706
[Journal Article] HLA class I down-regulation by HIV-1Nef: What might we learn from naturalsequence variants?2013
- Author(s)
  Philip Mwimanzi, Tristan J. Markle,Takamasa Ueno, Mark A. Brockman
- Journal Title
  
  Viruses
  
  Volume: 4 Issue: 9 Pages: 1711-1730
- DOI
  10.3390/v4091711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
[Journal Article] Attenuation of multiple Neffunctions in HIV-1 elite controllers2013
- Author(s)
  Philip Mwimanzi, Tristan J Markle,Eric Martin, Yoko Ogata, Xiaomei TKuang, Michiyo Tokunaga, MacdonaldMahiti, Florencia Pereyra, ToshiyukiMiura, Bruce D Walker, Zabrina L Brumme,Mark A Brockman and *Takamasa Ueno
- Journal Title
  
  Retrovirology
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1186/1742-4690-10-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232, KAKENHI-PROJECT-24390254
[Journal Article] Minorcontribution of HLA class I-associatedselective pressure to the variabilityof HIV-1 accessory protein Vpu2012
- Author(s)
  Zafrul Hasan, Jonathan M Carlson,Hiroyuki Gatanaga, Anh Q. Le, ChansonJ Brumme, Shinichi Oka, Zabrina LBrumme, *Takamasa Ueno
- Journal Title
  
  Biochem. Biophys. Res. Comm
  
  Volume: 421 Issue: 2 Pages: 291-295
- DOI
  10.1016/j.bbrc.2012.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-24390254
[Journal Article] Effects of naturally-arising HIV Nefmutations on cytotoxic T lymphocyterecognition and Nef's functionality inprimary macrophages2011
- Author(s)
  Philip Mwimanzi, Zafrul Hasan, RanyaHassan, Shinya Suzu, Masafumi Takiguchiand*TakamasaUeno
- Journal Title
  
  etrovirology
  
  Volume: 8 Issue: 1 Pages: 50-50
- DOI
  10.1186/1742-4690-8-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089, KAKENHI-PROJECT-23659232
[Journal Article] Theidentification of a small moleculecompound that reduces HIV-1Nef-mediated viral infectivityenhancement2011
- Author(s)
  Nopporn Chutiwitoonchai, MasateruHiyoshi, Philip Mwimanzi, TakamasaUeno, Akio Adachi, Hirotaka Ode,Hironori Sato, Oliver T. Fackler,Seiji Okada, Shinya Suzu
- Journal Title
  
  PLoS ONE
  
  Volume: 6(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089
[Journal Article] Differentin vivo effects of HIV-1immunodominant epitope-specific CTLson selection of escape mutant viruses2010
- Author(s)
  Koizumi H, Hashimoto M, Fujiwara M,Murakoshi H, Chikata T, Borghan MA,Hachiya A, Kawashima Y, Takata H, UenoT, Oka S, Takiguchi M
- Journal Title
  
  Journal of Virology
  
  Volume: 84 Pages: 5508-5519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089
[Journal Article] Failure of effectorfunction of human CD8+ T cells inNOD/SCID/JAK3-/- immunodeficient micetransplanted with human CD34+hematopoietic stem cells2010
- Author(s)
  Yoshinori Sato, Hiroshi Takata, NaokiKobayashi, Sayaka Nagata, NaomiNakagata, Takamasa Ueno, MasafumiTakiguchi
- Journal Title
  
  PLoS ONE
  
  Volume: 5(10) Issue: 10 Pages: e13109-e13109
- DOI
  10.1371/journal.pone.0013109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089
[Journal Article] Naturallyarising HIV-1 Nef variants conferringescape from cytotoxic T lymphocytesinfluence viral entry co-receptorexpression and susceptibility tosuperinfection2010
- Author(s)
  Philip Mwimanzi, Zafrul Hasan, MichiyoTokunaga, Hiroyuki Gatanaga, Shinichi Oka, *Takamasa Ueno
- Journal Title
  
  Biochem. Biophys. Res.Comm
  
  Volume: 403 Pages: 422-427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089
[Journal Article] Dynamicinterplay between viral adaptation andimmune recognition during HIV-1infection2010
- Author(s)
  Chihiro Motozono, Philip Mwimanzi,*Takamasa Ueno
- Journal Title
  
  Protein & Cell
  
  Volume: 1 Pages: 514-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390089
[Journal Article] Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection.2010
- Author(s)
  Chihiro Motozono, Philip Mwimanzi, Takamasa Ueno
- Journal Title
  
  Protein & Cell
  
  Volume: 1 Pages: 514-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659115
[Journal Article] Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral acivity of HIV-specific CTL2009
- Author(s)
  C Motozono, S Yanaka, K Tsumoto, M Takiguchi, T Ueno
- Journal Title
  
  J.Immunol 182
  
  Pages: 5528-5536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659115
[Journal Article] Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress HIV-1 replication in HIV-1-infected CD4+T cells and macrophages2009
- Author(s)
  Zheng N, Fujiwara M, Ueno T, Oka S, Takiguchi M
- Journal Title
  
  J.Virol 83
  
  Pages: 7668-7677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659115
[Journal Article] Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms2009
- Author(s)
  R Hassan, S Suzu, M Hiyoshi, N T-Makise, T Ueno, T Agatsuma, H Akari, J Komano, Y Takebe, K Motoyoshi, S Okada
- Journal Title
  
  J Cell Physiol 221
  
  Pages: 458-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659115
[Journal Article] Impact of intrinsic cooperative thermodynamics of peptide-MHC complexes on antiviral acivity of HIV-specific CTL2009
- Author(s)
  Chihiro Motozono, Saeko Yanaka, Kouhei Tsumoto, Masafumi Takiguchi, Takamasa Ueno
- Journal Title
  
  Journal of Immunology 182
  
  Pages: 5528-5536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241-249 epitope2008
- Author(s)
  Tetsuo Tsukamoto, Sachi Dohki, Takamasa Ueno, Miki Kawada, Akiko Takeda, Michio Yasunami, Taeko Naruse, Akinori Kimura, Masafumi Takiguchi, and Tetsuro Matano
- Journal Title
  
  AIDS 22
  
  Pages: 993-994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008
- Author(s)
  Takamasa Ueno
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 1107-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Cytotoxic T lymphocyte-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008
- Author(s)
  Takamasa Ueno
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 1107-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008
- Author(s)
  Takamasa Ueno, Chihiro Motozono, Sachi Dohki, Philip Mwimanzi, Susanne Rauch, Oliver T. Fackler, Shinichi, Oka, Masafumi Takiguchi
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 1107-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007
- Author(s)
  Takamasa Ueno, Yuka Idegami, Chihiro Motozono, Shinichi, Oka, Masafumi Takiguchi
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 5513-5523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs.2007
- Author(s)
  Takamasa Ueno, et al.
- Journal Title
  
  Journal of Immunology (in press)
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Altering effects of antigenic variations of HIV-1 on the antiviral effectiveness of HIV-specific CTLs2007
- Author(s)
  Takamasa Ueno, et al.
- Journal Title
  
  The Journal of Immunology 178
  
  Pages: 5513-5523
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007
- Author(s)
  Takamasa Ueno
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 5513-5523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590479
[Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs.2007
- Author(s)
  Takamasa Ueno, et al.
- Journal Title
  
  Journal of Immunology (in press)
- Data Source
  KAKENHI-PROJECT-17047034
[Journal Article] Altering effects of antigenic variations in HIV-1 on antiviral effectiveness of HIV-specific CTLs2007
- Author(s)
  Takamasa Ueno, et al.
- Journal Title
  
  The Journal of Immunology 178
  
  Pages: 5513-5523
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] HLAアリル多型性とHIV感染症2006
- Author(s)
  上野貴将
- Journal Title
  
  診断と治療 94(12)
  
  Pages: 121-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005
- Author(s)
  Takamasa Ueno, Masafumi Takiguchi
- Journal Title
  
  The Journal of AIDS Research 7・3
  
  Pages: 155-160
- NAID
  130003710521
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005
- Author(s)
  Takamasa Ueno, Masafumi Takiguchi
- Journal Title
  
  The Journal of AIDS Research 7・3
  
  Pages: 155-160
- NAID
  130003710521
- Data Source
  KAKENHI-PROJECT-17047034
[Journal Article] クラスI MHC拘束性抗原提示機構2005
- Author(s)
  上野貴将
- Journal Title
  
  臨床免疫学(上) 63・4
  
  Pages: 304-308
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Cytotoxic T lymphocyte-mediated immune responses to HIV.2005
- Author(s)
  Takamasa Ueno, et al.
- Journal Title
  
  The Journal of AIDS Research 7(3)
  
  Pages: 155-160
- NAID
  130003710521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] HIVに対する細胞傷害性T細胞の免疫応答2005
- Author(s)
  上野貴将ら
- Journal Title
  
  The Journal of AIDS Research 7(3)
  
  Pages: 155-160
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590419
[Journal Article] Functionally impaired HIV-specific CD8 T cells show high-affinity T cell receptor-ligand interactions.2004
- Author(s)
  Takamasa Ueno
- Journal Title
  
  J.Immunol. 173
  
  Pages: 5451-5457
- Data Source
  KAKENHI-PROJECT-16043244
[Journal Article] Reconstitution of anti-HIV effector functions of primary human CD8 T lymphocytes by transfer of HIV-specific αβ TCR genes.2004
- Author(s)
  Takamasa Ueno
- Journal Title
  
  J.Immunol. 34・12
  
  Pages: 3379-3388
- Data Source
  KAKENHI-PROJECT-16043244
[Patent] T細胞受容体を模倣する抗体断片及びその製造方法2008
- Inventor(s)
  熊谷泉、梅津光央、渡邊秀樹、上野貴将、本園千尋
- Industrial Property Rights Holder
  熊谷泉、梅津光央、渡邊秀樹、上野貴将、本園千尋
- Industrial Property Number
  2008-135007
- Filing Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] Analysis of cross-neutralising antibodies and T cell responses against Sars CoV 2 among infected and or vaccinated individuals in Dar es salaam Tanzania2023
- Author(s)
  Lilian Nkinda, Godfrey Barabona, Mark Ndubi, Isaac Ngare, Emmanuel Nkuwi, Doreen Kamori, Agricola Joachim, Sayoki Mfinanga, Senkoro Mbazi, Eligius Lyamuya, Takamasa Ueno, Emmanuel Balandya
- Organizer
  IUIS 2023 (International Congress of Immunology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0148
[Presentation] SARS-CoV-2抗原変異に対するHLA-A*24:02拘束性T細胞受容体の交差反応性2023
- Author(s)
  仲摩健、浜名洋、Huanyu Li、後藤由比古、有津由樹、豊田真子、Toong Seng Tan、北松瑞生、宇高恵子、岸裕幸、上野貴将、本園千尋
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24378
[Presentation] Heterogeneity in Neutralizing Antibody Responses following COVID-19 Vaccination in Japanese People Living with HIV2023
- Author(s)
  Isaac Ngare, Rumi Minami, Teruhisa Fujii, Toong Seng Tan, Takeo Kuwata, Soichiro Takahama, Emiko Nakashima, Naoya Yamazaki, Mako Toyoda, Chihiro Motozono, Takamasa Ueno
- Organizer
  the 12th IAS Conference on HIV Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24378
[Presentation] Analysis of cross-neutralising antibodies and T cell responses against Sars CoV 2 among infected and or vaccinated individuals in Dar es salaam Tanzania2023
- Author(s)
  Lilian Nkinda, Godfrey Barabona, Mark Ndubi, Isaac Ngare, Emmanuel Nkuwi, Doreen Kamori, Agricola Joachim, Sayoki Mfinanga, Senkoro Mbazi, Eligius Lyamuya, Takamasa Ueno, Emmanuel Balandya
- Organizer
  International Congress of Immunology (IUIS 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24378
[Presentation] Patient-derived envelope sequences are differentially resistant to SERINC5-mediated restriction of HIV-1 infectivity2023
- Author(s)
  Emmanuel Nkuwi,George P.Judicate,Toong Seng Tan, Godfrey Barabona, Mako Toyoda, Kaho Matsumoto, Takeo Kuwata,Shuzo Matsushita, Bruno Sunguya, Doreen Kamori, Takamasa Ueno
- Organizer
  IAS 2023, the 12th IAS Conference on HIV Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0148
[Presentation] Differential sensitivity of patient-derived envelope sequences to SERINC5-mediated restriction of HIV-1 infectivity2021
- Author(s)
  Emmanuel Nkuwi, George P. Judicate, Toong Seng Tan, Godfrey Barabona, Mako Toyoda, Takamasa Ueno
- Organizer
  Cold Spring Harbor Laboratory Meetings-Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] Plasma IL-21 associates with HIV-1 Neutralizing Potency of polyclonal IgG in the periphery2021
- Author(s)
  Isaac Ngare, Takeo Kuwata, Godfrey Barabona, Takamasa Ueno
- Organizer
  11th IAS Conference on HIV Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] Maraviroc less sensitive HIV-1 variants in a region where multiple non-B subtypes co-circulate2021
- Author(s)
  George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Takeo Kuwata, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  HIV research for prevention (HIVR4P)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] HIV-1の多型性から宿主との関連性を探る2021
- Author(s)
  上野貴将
- Organizer
  日本エイズ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] Inflammatory biomarkers but not latent reservoir size is associated with degree of immunosuppression in Tanzanians treated at advanced HIV disease2020
- Author(s)
  Godfrey Barabona, Macdonald Mahiti, Mako Toyoda, Doreen Kamori, Salim Masoud, George P Judicate, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  第34回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] Functional characterization of HIV-1 envelopes from Tanzania where multiple non-B co-circulates2020
- Author(s)
  George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Takeo Kuwata, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  第34回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03703
[Presentation] Implications of circulating HIV drug resistance mutations in Tanzania’s ART program; analysis of virally suppressed, treatment failure and ART naïve subjects2019
- Author(s)
  G Barabona, G Judicate, M Mahiti, S Masoud, D Kamori, P Mbelele, AS Mgunya, L Minja, B Sunguya, U Shigemi, M Matsuda, A Hachiya, E Lyamuya, T Ueno
- Organizer
  第33回日本エイズ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05822
[Presentation] 29.The presence and possible role of virus-host chimeric transcripts in adult T-cell leukemia-lymphoma.2019
- Author(s)
  Katsuya H, Miyazato P, Islam S, Tan BJY, Inada Y, Matsuo M, Ueno T, Tokunaga M, Hata H, Yamagishi M, Fujisawa J, Watanabe T, Uchimaru K, Utsunomiya A, Kimura S, Satou Y.
- Organizer
  62nd Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0230
[Presentation] Characterization of Currently Circulating HIV-1 Envelope Sequences in Tanzania2019
- Author(s)
  George Judicate, Godfrey Barabona, Macdonald Mahiti, Salim Masoud, Doreen Kamori, Amina Shaban Mgunya, Takeo Kuwata, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  第33回日本エイズ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19686
[Presentation] Identification and Molecular Characterization of a New HTLV-1 Enhancer2019
- Author(s)
  Misaki Matsuo, Takaharu Ueno, Paola Miyazato, Hiroo Katsuya, Saiful Islam, Benjy Tan, Saori Iwase, Masahito Tokunaga, Kisato Nosaka, Atae Utsunomya, Jun-ichi Fujisawa, Yorifumi Satou，
- Organizer
  19th International Conference on Human Retrovirology: HTLV and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0230
[Presentation] HIV immune evasion mechanisms and disease association revealed by MUHAS graduates.2018
- Author(s)
  Takamasa Ueno
- Organizer
  6th MUHAS SCIENTIFIC CONFERENCE
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19686
[Presentation] Molecular Characterization of a New HTLV-1 Enhancer. - HTLV-1内に存在する新規エンハンサー領域の分子メカニズム解析2018
- Author(s)
  松尾美沙希、上野孝治、宮里パオラ、勝屋弘雄、徳永雅仁、野坂生郷、宇都宮與、藤澤順一、佐藤賢文
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0230
[Presentation] CIRCULATING HIV-1 DRUG RESISTANCE MUTATIONS IN DAR ES SALAAM TANZANIA; IMPLICATION TO PRE EXPOSURE PROPHYLAXIS2018
- Author(s)
  Godfrey Barabona, Macdonald Mahiti, Salim Masoud, Peter Mbelele, Amina Shaban Mgunya, Lilian Minja, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  HIVR4P2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19686
[Presentation] CIRCULATING HIV-1 DRUG RESISTANCE MUTATIONS IN DAR ES SALAAM TANZANIA; IMPLICATION TO PRE EXPOSURE PROPHYLAXIS.2018
- Author(s)
  Godfrey Barabona, Macdonald Mahiti, Salim Masoud, Peter Mbelele, Amina Shaban Mgunya, Lilian Minja, Bruno Sunguya, Eligius Lyamuya, Takamasa Ueno
- Organizer
  HIVR4P2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822
[Presentation] HIV immune evasion mechanisms and disease association revealed by MUHAS graduates.2018
- Author(s)
  Takamasa Ueno
- Organizer
  6th MUHAS SCIENTIFIC CONFERENCE
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822
[Presentation] Relative resistance of MHC-B to Nef-mediated downregulation is conserved among lentiviruses and correlates with reduced viral loads in HIV-1-infected patient2017
- Author(s)
  Francis Mwimanzi, Macdonald Mahiti, Mako Toyoda, Frank Kirchhoff, Thumbi Ndung’u, Takamasa Ueno
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K15284
[Presentation] MHCとHIV-1 Nefとの相互作用と免疫制御への影響2017
- Author(s)
  上野貴将
- Organizer
  第26回日本組織適合性学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15284
[Presentation] Relative resistance of HLA-B for downregulation by Nef is a fundamental property across lentiviral lineage2017
- Author(s)
  Francis Mwimanzi, Macdonald Mahiti, Toyoda Mako, Jaclyn K Mann, Thumbi Ndung’u, Takamasa Ueno
- Organizer
  9th International AIDS Society Conference on HIV Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05822
[Presentation] Relative resistance of HLA-B for downregulation by Nef is a fundamental property across lentiviral lineage2017
- Author(s)
  Francis Mwimanzi, Macdonald Mahiti, Toyoda Mako, Jaclyn K Mann, Thumbi Ndung’u, Takamasa Ueno
- Organizer
  9th International AIDS Society Conference on HIV Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15284
[Presentation] MHCとHIV-1 Nefとの相互作用と免疫制御への影響2017
- Author(s)
  上野貴将
- Organizer
  第26回日本組織適合性学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05822
[Presentation] Poor disease Prognostication by a naturally-arising polymorphism within functional region of HIV-1 Nef2014
- Author(s)
  Stanley M, Hasan Z, Gatanaga H, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Takamasa Ueno
- Organizer
  Conference on Retroviruses and Opportunistic Infections
- Place of Presentation
  ボストン・アメリカ
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Effects of naturally occurring polymorphisms in functional domains of HIV-1 nef on in vivo disease progression2013
- Author(s)
  Stanley M, Hasan Z, Gatanaga H, Miura T, Kawana-Tachikawa A, Iwamoto A, Oka S, Takamasa Ueno
- Organizer
  The 27th Annual meeting of Japanese Society for AIDS Research
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] and the Acute HIVand International HIV Controllersstudy group. Reduced HIV-1 NefFunction in Acute/Early Individualswho become Viremic Controllers2013
- Author(s)
  X. Kuang, A Le, P Mwimanzi, T Markle,R Danroth, T Ueno, T Miura, B Walker,Z Brumme, M Brockman
- Organizer
  20thConference on Retroviruses andOpportunistic Infections (CROI)
- Place of Presentation
  Georgia World Congress Center, Atlanta,USA
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Reduced HIV-1 Nef Function in Acute/Early Individuals who become Viremic Controllers.2013
- Author(s)
  X. Kuang, A Le, P Mwimanzi, T Markle, R Danroth, T Ueno, T Miura, B Walker, Z Brumme, M Brockman, and the Acute HIV and International HIV Controllers study group.
- Organizer
  The 20th Conference on Retroviruses and Opportunistic Infections (CROI)
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] HLA class I-mediatedsequence polymorphism in HIV-1accessory protein Vpu2012
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme,Takamasa Ueno
- Organizer
  The 13thKUMAMOTO AIDS Seminar and GCOE JointInternational Symposium
- Place of Presentation
  Hotel NikkoKumamoto and Aso Resort GrandvrioHotel, Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impact of HLA class I-driven geneticvariability in HIV-1 accessory genevpu2012
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, S. Oka, Z. Brumme, Takamasa Ueno
- Organizer
  COLD SPRING HARBOR ASIACONFERENCES: Frontiers of Immunologyin Health and Disease
- Place of Presentation
  Suzhou DushuLake Conference Center, China
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Nef のウイルスレセプター発現低下機能と病態2012
- Author(s)
  緒方陽子、Philip Mwimanzi、李小光、徳永美知代、Tristan Markle、三浦聡之、Bruce Walker 、Zabrina Brumme 、MarkBrockman、上野貴将
- Organizer
  第26回日本エイズ学会学術集会・総会
- Place of Presentation
  慶應義塾大学日吉キャンパス(神奈川)
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Functional impairment of HIV-1 Nef in elite controllers and its correlation with immune-mediated selective pressure.2012
- Author(s)
  T. Ueno
- Organizer
  13th Kumamoto AIDS Seminar Global COE Joint International Symposium
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Modulation of HIV-1Nef-mediated HLA class Idown-regulation activity duringdisease progression2012
- Author(s)
  M. Mahiti, P. Mwimanzi, Y. Ogata, M.Tokunaga, B. Walker, Z. Brumme, M.Brockman, T. Ueno
- Organizer
  13th KumamotoAIDS seminar Aso Resort GrandiovrioHotel
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Modulation of HIV-1Nef-mediated HLA class Idown-regulation activity duringdisease progression2012
- Author(s)
  M. Mahiti, P. Mwimanzi, Y. Ogata, M.Tokunaga, B. Walker, Z. Brumme, M.Brockman, T. Ueno
- Organizer
  13th KumamotoAIDS seminar
- Place of Presentation
  Aso Resort GrandiovrioHotel, Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] HIV-1 immune escape andcross-reactivity profiles ofvirus-specific cytotoxic Tlymphocytes, YIS-A Session II2012
- Author(s)
  Chihiro Motozono, John J. Miles,Zafrul Hasan, Hiroyuki Gatanaga,Meribe Stanley, Shinichi Oka, MasaakiMiyazawa, Andrew K. Sewell, TakamasaUeno
- Organizer
  13thKumamoto AIDS Seminar Global COE JointInternational Symposium
- Place of Presentation
  Aso ResortGRANDVRIO, Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Functional impairment ofHIV-1 Nef in elite controllers and itscorrelation with immune-mediatedselective pressure2012
- Author(s)
  T. Ueno
- Organizer
  13th Kumamoto AIDSSeminar Global COE Joint InternationalSymposium
- Place of Presentation
  Aso Resort GrandvrioHotel,Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] The impact of a single amino acid difference in CDR3・onTCR・・・cross-reactivity、ワークショップ 32 ヒト免疫、2012
- Author(s)
  Chihiro Motozono, John S. Bridgeman,Masaaki Miyazawa, Andrew K. Sewell andTakamasa Ueno
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場、兵庫
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] HIV-1 Nef の遺伝子多型性と機能的可塑性2012
- Author(s)
  上野貴将
- Organizer
  第14回白馬シンポジウムin 京都
- Place of Presentation
  京都市国際交流会館
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Genetic and functional analyses of HIV-1 Nef in elite controllers.2012
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga, A. Le, C. Brumme, S. Oka, Z. Brumme, Takamasa Ueno.
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] HLA-B35拘束性HIV特異的TCRは野生型抗原に高い特異性を有する2012
- Author(s)
  本園千尋、John J. Miles、宮澤正顯、上野貴将、Andrew K. Sewell
- Organizer
  第21回組織適合性学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] The impact of a single amino acid difference in CDR3a on TCR ab cross-reactivity.2012
- Author(s)
  Chihiro Motozono, John S. Bridgeman, Masaaki Miyazawa, Andrew K. Sewell and Takamasa Ueno.
- Organizer
  第41回日本免疫学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] HLA-B35 拘束性 HIV 特異的 TCR は野生型抗原に高い特異性を有する、学術賞ならびに学術奨励賞候補口演2012
- Author(s)
  本園千尋、John J. Miles、宮澤正顯、上野貴将、Andrew K. Sewell
- Organizer
  第21回組織適合性学会大会
- Place of Presentation
  明治大学、東京
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] HIV-1 immune escape and cross-reactivity profiles of virus-specific cytotoxic T lymphocytes, YIS-A Session II.2012
- Author(s)
  Chihiro Motozono, John J. Miles, Zafrul Hasan, Hiroyuki Gatanaga, Meribe Stanley, Shinichi Oka, Masaaki Miyazawa, Andrew K. Sewell, Takamasa Ueno.
- Organizer
  The13th Kumamoto AIDS Seminar Global COE Joint International Symposium
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Modulation of HIV-1 Nef-mediated HLA class I down-regulation activity during disease progression.2012
- Author(s)
  M. Mahiti, P. Mwimanzi, Y. Ogata, M. Tokunaga, B. Walker, Z. Brumme, M. Brockman, T. Ueno
- Organizer
  13th Kumamoto AIDS seminar
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Effect of HLA class I-mediatedselective pressure on HIV-1 accessorygenes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  International Union ofMicrobiological Societies 2011Congress: Virus and host response
- Place of Presentation
  Sapporo Convention Center, Sapporo,Japan
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes in Japanese sequences. KeystoneSymposia HIV Evolution2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  Genomics andPathogenesis
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  2011 The Annual Meeting of theJapanese Society for Immunology
- Place of Presentation
  Chiba,Makuhari Messe, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impairment of virioninfectivity by nef alleles from HIVelite controllers2011
- Author(s)
  Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
- Organizer
  Keystone SymposiaHIV Evolution
- Place of Presentation
  Genomics andPathogenesis, Canada
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impaired viralinfectivity and viral replicationcapacity by nef alleles from HIV elitecontrollers2011
- Author(s)
  Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
- Organizer
  25th Annual Meeting ofJapanese Society for AIDS Research
- Place of Presentation
  Tokyo Hyatt Regency, Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Nef のウイルスレセプター発現低下機能と病態2011
- Author(s)
  緒方陽子、大津家裕仁、Philip Mwimanzi、徳永美知代、Tristan Markle、三浦聡之、Bruce Walker 、Zabrina Brumme 、MarkBrockman、上野貴将
- Organizer
  一般演題「アクセサリー遺伝子-2」第25回日本エイズ学会学術集会・総会
- Place of Presentation
  ハイアットリージェンシー東京
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Subtle effect of HLA classI-driven selective forces on thevariability of HIV-1 accessory genes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  12th Kumamoto AIDS Seminar and GCOEJoint International Symposium
- Place of Presentation
  HotelNikko Kumamoto and Aso ResortGrandvrio Hotel, Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Effect of HLA class I-mediatedselective pressure on HIV-1 accessorygenes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  International Union ofMicrobiological Societies 2011Congress: Virus and host response
- Place of Presentation
  Sapporo Convention Center, Sapporo,Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Subtle effect of HLA classI-driven selective forces on thevariability of HIV-1 accessory genes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  12th Kumamoto AIDS Seminar and GCOEJoint International Symposium
- Place of Presentation
  HotelNikko Kumamoto and Aso ResortGrandvrio Hotel, Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impairment ofviral replication capacity by nefalleles from HIV elite controllers.Frontiers of Retrovirology2011
- Author(s)
  Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, MarkBrockman,Takamasa Ueno
- Organizer
  Complexretroviruses, retroelements and theirhosts
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Thecross-reactivity footprints ofHIV-specific CTLs2011
- Author(s)
  Chihiro Motozono, John J. Miles, LindaWooldridge, David A. Price, TakamasaUeno, Andrew K. Sewell
- Organizer
  12th Kumamoto AIDSSeminar and GCOE Joint InternationalSymposium
- Place of Presentation
  Hotel Nikko Kumamoto and Aso Resort Grandvrio Hotel, Kumamoto,Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impairment of virioninfectivity by nef alleles from HIVelite controllers2011
- Author(s)
  Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
- Organizer
  Nef activity inenhancement of virion infectivity isimpaired in HIV elite controllers
- Place of Presentation
  XV,International Congress of Virology,Sapporo Convention Center,Sapporo,Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Population analysis ofviral replication capacity by nefalleles of HIV elite controllers2011
- Author(s)
  Philip Mwimanzi, Tristan Markle,Michiyo Tokunaga, Toshiyuki Miura,Eric Martin, Florencia Pereyra, BruceWalker, Zabrina Brumme, Mark Brockman,Takamasa Ueno
- Organizer
  12thKumamoto AIDS Seminar
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Impact of HLA class I-drivengenetic variability in HIV-1 accessorygenes2011
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga,A. Le, C. Brumme, S. Oka, Z. Brumme, T.Ueno
- Organizer
  2011 The Annual Meeting of theJapanese Society for Immunology
- Place of Presentation
  Chiba,Makuhari Messe, Japan
- Data Source
  KAKENHI-PROJECT-23659232
[Presentation] Implication of the effects of hostimmune responses on the HIV-1 vpu geneevolution2010
- Author(s)
  Zafrul Hasan, Hiroyuki Gatanaga,Shinichi Oka, and Takamasa Ueno
- Organizer
  24th Annual Meeting of theJapanese Society for AIDS Research
- Place of Presentation
  Grand Prince Hotel Takanawa, PrinceSakura Tower, Takanawa, Tokyo
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Implication of the effects of hostimmune responses on the HIV-1 vpu geneevolution2010
- Author(s)
  Zafrul Hasan, Hiroyuki Gatanaga,Shinichi Oka, and Takamasa Ueno
- Organizer
  The 11th KUMAMOTO AIDSSeminar and GCOE Joint InternationalSymposium
- Place of Presentation
  Hotel Nikko Kumamoto andAso Resort Grandvrio Hotel, Kumamoto,Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] CTL-escape Nefvariants influence CCR5 downregulation and HIV superinfectionsusceptibility2010
- Author(s)
  Mwimanzi P., Ueno T
- Organizer
  The 14thInternational Conference ofImmunology (ICI)
- Place of Presentation
  Kobe InternationalExhibition and Portopia Hotel, Kobe,Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] Nef activity in downregulation of viral receptors andprotection of HIV superinfection ismodulated by Nef mutations that conferCTL escape during acute infection2010
- Author(s)
  Mwimanzi, P., Oniangue-Ndza, C., AllenT.M., and Ueno,T
- Organizer
  11th KUMAMOTO AIDS Seminar GCOE JointInternational Symposium
- Place of Presentation
  Hotel NikkoKumamoto and Aso Grand Vrio Hotel,Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-22390089
[Presentation] CTL-mediated selective pressure and pathogenic functions of Nef2009
- Author(s)
  Ueno, T.
- Organizer
  Meeting on HIV research in Mexico
- Place of Presentation
  Mexico City, Mexico
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21659115
[Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages2009
- Author(s)
  Philip Mwimanzi, M. Fujiwara, M. Takiguchi, Takamasa Ueno
- Organizer
  Keystone Symposium -HIV immunobiology : From Infection to Immune Control, Keystone Resort, Keystone
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] Antiviral activity of HIV-specific cytotoxic T lymphocytes is influenced by intrinsic cooperative thermodynamics of peptide-MHC complexes2009
- Author(s)
  C. Motozono, S. Yanaka, K. Tsumoto, M. Takiguchi, Takamasa Ueno
- Organizer
  Keystone Syposium -HIV immunobiology : From Infection to Immune Control, Keystone Resort, Keystone
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] HIV特異的T細胞の抗原特異性と抗原変異に対する交差反応性、一般口演「レンチウイルス、HIV(7)」2008
- Author(s)
  本園千尋、滝口雅文、上野貴将
- Organizer
  第56回日本ウイルス学会学術集会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] 抗原ペプチド・MHC複合体の安定性はT細胞の抗ウイルス機能に影響する、ワークショップ「ウイルス感染-2」2008
- Author(s)
  本園千尋、滝口雅文、上野貴将
- Organizer
  第38回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The balance of power : Nef and CTL2008
- Author(s)
  Takamasa Ueno
- Organizer
  9th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] 抗原ペプチド複合体の内在的安定性はCTLの抗ウイルス活性に影響する、一般口演「O-37)免疫」2008
- Author(s)
  本園千尋、滝口雅文、上野貴将
- Organizer
  第22回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2008
- Author(s)
  Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
- Organizer
  XVII International AIDS Conference
- Place of Presentation
  Mexico City
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The effect of TCR-peptide-MHC interactions on antiviral activity and cross-reactive capacity of HIV-specific CTLs2008
- Author(s)
  Chihiro Motozono, Masafumi Takiguchi, and Takamasa Ueno
- Organizer
  Keystone Symposia -HIV Pathogenesis-
- Place of Presentation
  Banff, Canada
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] ヒト免疫監視システムとHIVの適応馴化2008
- Author(s)
  上野貴将
- Organizer
  第22回日本エイズ学会学術集会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages、一般口演「O-35)アクセサリー」2008
- Author(s)
  Mwimanzi Philip、藤原守、滝口雅文、上野貴将
- Organizer
  第22回日本エイズ学会学術集会・総会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The effects of CTL-escape conferring mutations on Nef's pathogenic functions in primary macrophages2008
- Author(s)
  Philip Mwimanzi, Mamoru Fujiwara, Masafumi Takiguchi, Takamasa Ueno
- Organizer
  9th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] ヒト免疫監視システムとHIVの適応馴化シンポジウム「ヒトはなぜエイズになるのか」2008
- Author(s)
  上野貴将
- Organizer
  第22回日本エイズ学会学術集会
- Place of Presentation
  大阪国際交流センター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The decay of peptide-MHC complex influences antiviral activity of HIV-specific CTLs2008
- Author(s)
  Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno
- Organizer
  9th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The capacity of antigenic peptides that dictates antiviral activity of Cytotoxic T Lymphocytes2007
- Author(s)
  Chihiro Motozono, Masafumi Takiguchi, Takamasa Ueno
- Organizer
  8th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007
- Author(s)
  T.Ueno
- Organizer
  AIDS Vaccine Conference
- Place of Presentation
  Seattle,WA.U.S.A.
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] Ability of HIV-1-specific CTL to suppress HIV-1 replication and selection of escape mutants in chronically HIV-1-infected individuals2007
- Author(s)
  Koizumi, H., Iwatani, T., Hachiya, A., Kawashima, Y., Ueno, T., Oka, S., and Takiguchi, M.
- Organizer
  8th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] The impact of CTL-mediated selective forces on pathogenic functions of HIV-1 Nef2007
- Author(s)
  Takamasa Ueno
- Organizer
  Center for AIDS Research, Kumamoto University, 10th Anniversary Symposium
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007
- Author(s)
  Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
- Organizer
  AIDS Vaccine 07
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007
- Author(s)
  Takamasa Ueno, Chihiro Motozono, Sachi Douki, Susanne Rauch, Philip Mwimanzi, Oliver T. Fackler, Shinichi Oka, Masafumi Takiguchi
- Organizer
  8th AIDS Seminar in KUMAMOTO
- Place of Presentation
  Kumamoto, Japan
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] HIV Nefの病原性機能維持と宿主免疫淘汰圧2007
- Author(s)
  上野貴将
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] HIV Nefの病原性機能維持と宿主免疫淘汰圧ワークショップ2007
- Author(s)
  上野貴将、本園千尋、道木佐知、岡慎一、滝口雅文
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure modulates pathogenic functions of HIV-1 Nef2007
- Author(s)
  Takamasa Ueno, Chihiro Motozono, Sachi Douki, Shinichi Oka, Masafumi Takiguchi
- Organizer
  Keystone Symposia-Molecular and Cellular Determinants of HIV Pathogenesis-
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] CTL-mediated selective pressure influences dynamic evolution and pathogenic functions of HIV-1 Nef2007
- Author(s)
  上野貴将、本園千尋、道木佐知、Philip Mwimanzi、岡慎一、滝口雅文
- Organizer
  ワークショップ第37回日本免疫学会総会・学術集会
- Place of Presentation
  高輪プリンスホテル
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-19590479
[Presentation] Dynamic range of down-regulation of HIV-1 entry receptors by primary Nef isolates.
- Author(s)
  Toyoda M, Ogata Y, Mahiti M, Pereyra F, Miura T, Walker BD, Brumme ZL, Brockman MA, Ueno T.
- Organizer
  The annual Conference on Retroviruses and Opportunistic Infections (CROI).
- Place of Presentation
  シアトル・アメリカ
- Year and Date
  2015-02-23 – 2015-02-26
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Effects of natural variability of Vpr on immunological footprints and protein functions.
- Author(s)
  Kamori D, Murakami T, Hasan Z, Meribe S, Carlson J, Siarot L, Miura T, Kawana-Tachikawa A, Iwamoto A, Gatanaga H, Oka S, Aida Y, Ueno T.
- Organizer
  Keystone Symposia HIV Vaccines (X5)
- Place of Presentation
  バンフ・カナダ
- Year and Date
  2015-03-22 – 2015-03-27
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Impact of HLA class I-driven genetic variability in HIV-1 accessory gene vpu.
- Author(s)
  Zafrul Hasan, J. Carlson, H. Gatanaga, A. Le, S. Oka, Z. Brumme, Takamasa Ueno.
- Organizer
  COLD SPRING HARBOR ASIA CONFERENCES: Frontiers of Immunology in Health and Disease.
- Place of Presentation
  中国蘇州
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] Differential down-regulation of the HLA class I allotypes by HIV-1 Nef primary isolate.
- Author(s)
  Mahiti M, Jia X, Toyoda M, Mwimanzi F, Walker BD, Brumme ZL, Brockman MA, Xiong Y, Ueno T.
- Organizer
  The annual Conference on Retroviruses and Opportunistic Infections (CROI).
- Place of Presentation
  シアトル・アメリカ
- Year and Date
  2015-02-23 – 2015-02-26
- Data Source
  KAKENHI-PROJECT-24390254

1. TAKIGUCHI Masafumi (00183450)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. 野村拓志 (80711001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MIURA Toshiyuki (00296576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. GATANAGA Hiroyuki (10466211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. KODAMA Eiichi (50271151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Satou Yorifumi (70402807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 冨山宏子 (50301370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 勝屋弘雄 (80632041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 桑田岳夫 (70346063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. BARABONA GODFREY (40906674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. IWATANI Yasumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. UEHA Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. Matsushima Kouji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 前田洋助

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 岸裕幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 本園千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UENO TAKAMASA 上野 貴将

UENO Takamasa 上野 貴将

Research Projects

Research Products

Co-Researchers

Impact of cross-reactive immunity to pre-existing infections on COVID-19 pathogenesis in East AfricaPrincipal Investigator

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Investigation for potential CTL epitopes spanning various coronavirues aiming for universal vaccine developmentPrincipal Investigator

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Tracking of defaulters from HIV treatment programs in developing countriesPrincipal Investigator

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Identification of broadly neutralizing antibodies to HIV-1 and its correlates with host genetic factorsPrincipal Investigator

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Molecular epidemiological study of vertically transmitted HIV positive young adultsPrincipal Investigator

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Dynamic evolution and different pathogenesis of HTLV-1 across multiple continents revealed by next generation sequencing technology

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Reinvestigating HIV-specific effector cells targeting latent reservoir cellsPrincipal Investigator

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Analysis of latently infected HIV-1 circulating in Sub-Sahara AfricaPrincipal Investigator

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抗原変異の著しい病原体に対するＨＬＡ分子システムの可塑性と脆弱性Principal Investigator

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Development of anti-HIV agents that exert synergism with host immune pressure

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A bioinformatics approach toward understanding interplay betweenchronic virus infections and human antiviral immune responsesPrincipal Investigator

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Functional adaptation of HIV accessory proteins towardimmune-mediated selective pressurePrincipal Investigator

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CTLの抗ウイルス機能におけるβ2ミクログロブリンの役割Principal Investigator

Principal Investigator

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UENO TAKAMASA 上野貴将

UENO Takamasa 上野貴将