SAKAMOTO NAOYA 坂本直哉

… Alternative Names

SAKAMOTO Naoya 坂本直哉

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Researcher Number	10334418
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 医学研究院, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 北海道大学, 医学研究院, 教授 2016: 北海道大学, 医学研究科, 教授 2012 – 2015: 北海道大学, 医学(系)研究科(研究院), 教授 2014: 北海道大学, 医学研究科, 教授 2014: 北海道大学, 大学院医学研究科, 教授 … More 2012: 北海道大学, 医学系研究科, 教授 2012: 北海道大学, 大学院・医学研究科, 教授 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄付講座教員 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員(准教授) 2010 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員 2009: 東京医科歯科大学, 医歯学総合研究科, 寄附講座准教授 2009: Tokyo Medical and Dental University, 医歯学総合研究科, 寄附講座教員 2008 – 2009: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 寄附講座准教授 2008: 東京医科歯科大学, 医歯学総合研究科, 准教授 2007: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 寄附講座教員 2006: Tokyo Medical and Dental University, Department of Gastroenerology and Hepatology, Associate Professor, 大学院医歯学総合研究科, 助教授 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 寄付講座教員 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座教員 2005: 東京医科歯科大学, 医学部付属病院, 助手 2005: Tokyo Medical and Dental University, Graduate school, Research associate, 大学院・医歯学総合研究科, 寄附講座教員 2002 – 2005: 東京医科歯科大学, 医学部附属病院, 助手 2004: Tokyo Medical and Dental Univ., Dept.of Gastroenteorology and Hepatology, Instructor, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Medium-sized Section 52:General internal medicine and related fields / Biological Sciences Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 肝線維化 / C型肝炎 / 抗ウイルス療法 / HCV-JFH1培養系 / 内科 / HCV replicon system / 遺伝子導入療法 / small interfering RNA / RNA interference / ウイルス学 … More / 医学 / ウイルス肝炎 / 肝炎ウイルス / HCVレプリコン / 肝発癌 / 糖鎖修飾 / DAA薬剤耐性 / 薬剤耐性 / 間葉系幹細胞 / 間葉系幹細胞 / 肝線維症 / 肝硬変 / 消化器内科 / high-throughput screening / type-I interferon / Interferon-stimulated genes / Cyclosporin A / Hepatitis C virus / siRNA / サイクロスポリンA / HCVレプリコン・システム / サイクロフィリン / スクリーニング / インターフェロン / 発現ライブラリー / サイクロスポリン / レプリコン / gene therapy / antiviral therapy / molecular targeted drug / adenovirus vector / hepatitis Ci virus / 分子標的治療 / アデノウイルスベクター / レプリコン・システム / C型肝炎ウイルス / 薬剤耐性変異 / 分子動力学シミュレーション / B型肝炎 / 基礎研究 / ウイルス / 感染症 / 医療 / CD81 / HCV / 小分子ライブラリー / HCV-Feoレプリコン / レプリコンシステム / HVC-JFH1培養系 / 原発性胆汁性肝硬変 / 胃癌 / 胃腺腫 / suppression subtractive hybridization … More Except Principal Investigator 再生医学 / 肝細胞 / HCV / 発生・分化 / 幹細胞 / 細胞移植 / インターフェロン / C型肝炎ウイルス / 肝癌幹細胞 / HBx / HCC / HBV / 肝癌 / FACS / 肝幹細胞 / HCVレプリコン / 抗ウイルス療法 / 分子標的治療 / レプリコン・システム / 肝線維化 / B型肝炎ウイルス / 細胞生物学 / 臍帯血 / interferon / replicon / IRF-1 / ＨＣＶ / RNAポリメラーゼ / 小胞体ストレス / 細胞障害効果 / プラークアッセイ / HCV-JFH1培養系 / Cardif / 慢性肝炎 / レプリコン / CXCL9 / FGFR4 / miRNA / 免疫寛容 / cancer stem like cells / 腫瘍免疫 / 肝がん / FGF / 免疫チェックポイント阻害剤 / 癌幹細胞 / R-Spondin / VOD/SOS / 肝GVHD / マクロファージ / 造血幹細胞移植 / 胆管上皮幹細胞 / オーガノイド / TGF-beta / GVHD / HBx蛋白 / HBc抗原 / HBs抗原 / 宿主制限因子 / 宿主因子 / バイオマーカー / NAFLD / 糖鎖マーカー / 糖鎖 / NASH / ドラッグスクリーニング / ハイスループット / IFN / 大規模スクリーニング / 抗HBV薬 / レポーター / 創薬 / drug screening / スクリーニング / 完全排除 / DDB1 / cccDNA / HBV cccDNA / ＨＢｘ / 癌 / CSCｓ / インテグレーション / HBｘ / 肝細胞癌 / truncated HBx / カルニチン / 肝脂肪化 / Hepatocytes / Cell biology / Cell therapy / Umbilical cord blood / Stem cells / Transplantation / Development ＆ Differentiation / Regenerative medicine / 傷害肝 / 再生医療 / 移植・再生医療 / cell biology / regenerative medicine / liver injury / cell transplantation / stem cells / hepatocytes / umbilical cord blood / SCIDマウス / NOD / linege marker / CD45 / アルブミン / ヒト臍帯血由来細胞 / 肝障害 / cyclophilin / HCV replicon system / Cyclosporin A / small interfering RNA / サイクロフィリン / レトロウイルスベクター / サイクロスポリンA / innate immunity / NS5A protein / Hepatitis C Virus / NF-KB / NS5A / microarray / NS5A領域 / interferon regulatory factor 3 / interferon sensitivity determining region / interferon regulatory factor 1 / 自然免疫 / NS5A蛋白 / 脂肪性肝炎 / 酸化ストレス / ストレス関連遺伝子 / Heat shock factor / HSF1 / 薬剤耐性ウイルス / ＩＦＮ / IL-6 / IFNλ / ＩＬ28Ｂ / ＮＳ4Ｂ / 細胞・組織 / 肝疾患治療 / 移植 / DAA製剤 / コア変異 / コア変異株 / インターロイキン６ / 肝発癌 / 治療抵抗性 / インターロイキン6 / C型慢性肝炎 / 治療抵抗性機序 / CD13 / 肝細胞移植 / 肝臓学 / ヒト肝臓キメラマウス / 生体発光共鳴エネルギー転移(Bioliminescence Resonance Energy ransfer) / STING / HCV-NS4B / RIG-I / HCV レプリコン / 細胞 / 細胞外マトリクス / shRNA / 遺伝子導入療法 / siRNA / 肝癌細胞 / 感染レセプター / Small interfering RNA / ウイルスベクター Less

肝線維化に関連する宿主因子を標的とした新規治療法の開発Principal Investigator
- Principal Investigator
  
  坂本直哉
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
肝癌のFGFR4-CXCL9 axis を介した免疫チェックポイント阻害剤耐性化機構の解析
- Principal Investigator
  
  荘拓也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Development of novel CAR-T therapy targeting hepatic stellate cell-specific oligosaccharide antigensPrincipal Investigator
- Principal Investigator
  
  坂本直哉
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hokkaido University
肝線維化治療標的同定とそれに基づく新規抗肝線維化治療法開発
- Principal Investigator
  
  須田剛生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Comprehensive search for host factors related to liver fibrosis mechanisms and development of novel therapeutic strategiesPrincipal Investigator
- Principal Investigator
  
  坂本直哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Elucidation of Maintenance and Immune Tolerance Mechanisms in hepatocellular carcinoma Stem Cells and Optimization of Therapeutic Approaches
- Principal Investigator
  
  Sho Takuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Glycan Modification Analysis as a Novel Diagnostic Marker and Therapeutic Target for Non-Alcoholic Fatty Liver Disease
- Principal Investigator
  
  Ogawa Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Development of novel antiviral therapy targeting hepatitis B virus host restriction factor
- Principal Investigator
  
  Morikawa Kenichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Targeting the glycosylated structure of liver tissue stromal proteins to form the basis for glycosylation drug discovery for liver fibrosis.Principal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Hokkaido University
Title of Research Project
- Principal Investigator
  
  Teshima Takanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Hokkaido University
High through anti-HBV drug screening by using reporter assay
- Principal Investigator
  
  Suda Goki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Comprehensive screening of miviroenvirinmental factors that affect liver fibrosisPrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hokkaido University
Development of drugs targeting liver fibrosis by modulation of protein/lipid glycosylationPrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Hokkaido University
A new development of antivirals for eradication of HBV cccDNA
- Principal Investigator
  
  Morikawa Kenichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Search for new cell- or small molecule-based therapies to promote regression of liver cirrohsisPrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Effect of truncated Hepatitis B virus X protein integration on malignant potential of HCC
- Principal Investigator
  
  Goki Suda
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Application of molecular dynamics simulation to construct of virtual assay system of antiviral drug resistancePrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Anti-Adipogenic and Antiviral Effects of L-Carnitine on Hepatitis C Virus Infection
- Principal Investigator
  
  koji ogawa
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Investigation of the HSF1 signaling pathway as the molecular targeted therapies for hepatocellular carcinoma.
- Principal Investigator
  
  Makoto Chuma
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
Establishment of virtual assay system by molecular dynamic simulation of HCV antiviral resistancePrincipal Investigator
- Principal Investigator
  
  Sakamoto Naoya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
To analyze the mechanisms of HCV drug resistance by using chimeric HCV cell culture system
- Principal Investigator
  
  SUDA Goki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
High throughput screening of chemical library for antiviral compounds for hepatitis virusesPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
Analysis of IL-6-mediated drug-resistance of hepatitis C virus infection
- Principal Investigator
  
  NAKAGAWA Mina
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Study on establishment of experimental animal model for chimeric liver with hepatitis C virus infection using induced hepatocyte-like cells
- Principal Investigator
  
  AZUMA Seishin
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Impaired host response and HCV disturbance of type I/III IFN signaling are closely associated with non-response to IFN-based anti-HCV treatment
- Principal Investigator
  
  OOKA Shinya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of drugs targeting hepatitis B x-proteinPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO NAOYA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Hokkaido University
細胞障害性HCV培養系を用いた重症C型肝炎発症機構の解析
- Principal Investigator
  
  筬島裕子
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Establishment of mouse-directed HCV infection modelsPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
High-throughput screening of virus-and host-targeted suppressors of HCV infectionPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
FRET/ BRET analysis of interaction between HCV protein and interferon signaling
- Principal Investigator
  
  FUJITA Megumi (TASAKA Megumi)
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of plaque assay to isolate cytopathic HCV clones
- Principal Investigator
  
  OOOKA Shinya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Analysis on molecular mechanisms of liver reconstitution by transplanted hepatic cells
- Principal Investigator
  
  AZUMA Seishin (CHEN Cheng-Hsin)
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Research on molecular mechanism of hepatic stem cell proliferation and development of mouse models for stem cell transplantation
- Principal Investigator
  
  KAKINUMA Sei
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Search for new classes of HCV therapeutics by large scale screening of antiviral compounds and host cellular factorsPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Research on transplantation of hepatic stem cells and development of experimental mouse models for hepatitis C virus
- Principal Investigator
  
  CHEN Cheng-hsin
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
C型肝炎ウイルス発現モデル動物を用いたsiRNAによる感染抑制系の開発
- Principal Investigator
  
  OOOKA Shinya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Suppression subraction法による消化器癌の分子病態の解析Principal Investigator
- Principal Investigator
  
  坂本直哉
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Study on hepatic differentiation of mesenchymal stem cells derived from human umbilical cord blood, and cell therapy for liver disease by use of mesenchymal stem cells.
- Principal Investigator
  
  CHEN Cheng-Hsin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Comprehensive screening of host proteins that suppress replication of HCV repliconPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Suppression of hepatitis C virus replication by cyclosporine A
- Principal Investigator
  
  OOOKA Shinya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Identification of human cord blood-derived hepatic stem cells, and establishment of cell therapy for lethal liver disease
- Principal Investigator
  
  KAKINUMA Sei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
  Tokyo Medical and Dental University
Therapeutic application of RNA interference to suppress hepatitis C virus replicationPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Naoya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
HCV VectorによるHCV感染過程の制御分子の同定
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Analysis of anti-interferon mechanism by HCV NS5A protein using HCV replicon system
- Principal Investigator
  
  ENOMOTO Nobuyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Yamanashi
  Tokyo Medical and Dental University

[Book] C型慢性肝炎・C型肝硬変. 日常診療に活かす診療ガイドラインUP-TO-DATE2018→2019.2018
- Author(s)
  森川賢一、坂本直哉.
- Total Pages
  1037
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-17K09400
[Book] C型肝炎-新薬開発の展望. B型・C型肝炎の抗ウイルス療法-最前線の治療エッセンス.2017
- Author(s)
  森川賢一、坂本直哉.
- Total Pages
  195
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-17K09400
[Book] 分子標的薬その作用機序と効果予測(肝細胞及び肝幹・前駆細胞移植におけるMatrix Metalloproteinaseの関与)2010
- Author(s)
  柿沼晴, 坂本直哉, 渡辺守, 他, 分著(小俣政男編集)
- Total Pages
  239
- Publisher
  アークメデイア
- Data Source
  KAKENHI-PROJECT-21590833
[Book] siRNAによるC型肝炎遺伝子治療.バイオ医薬品の開発技術とシーズ2009
- Author(s)
  坂本直哉、横田隆〓
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-21390226
[Book] 肝疾患レビュー 2□I : 肝炎ウイルスと自然免疫2006
- Author(s)
  坂本直哉(分担)
- Publisher
  日本メディカルセンター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Book] 肝疾患レビュー2006-2007:肝炎の基礎(4):肝炎ウイルスと自然免疫2006
- Author(s)
  坂本直哉(共著)
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-17590626
[Book] 肝疾患レビュー 2-I : 肝炎ウイルスと自然免疫2006
- Author(s)
  坂本直哉(分担)
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-17590626
[Book] 肝疾患Review20042004
- Author(s)
  坂本直哉, 榎本信幸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Book] 肝疾患Review20042004
- Author(s)
  坂本直哉, 榎本信幸
- Publisher
  HCV治療の基礎的戦略
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Changes in Serum Growth Factors during Resistance to Atezolizumab Plus Bevacizumab Treatment in Patients with Unresectable Hepatocellular Carcinoma2023
- Author(s)
  Yang Zijian、Suda Goki、Maehara Osamu、Ohara Masatsugu、Yoda Tomoka、Sasaki Takashi、Kohya Risako、Yoshida Sonoe、Hosoda Shunichi、Tokuchi Yoshimasa、Kitagataya Takashi、Suzuki Kazuharu、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Ogawa Koji、Ohnishi Shunsuke、Sakamoto Naoya
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 3 Pages: 593-593
- DOI
  10.3390/cancers15030593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K17039
[Journal Article] Serum Angiopoietin-2 Predicts the Occurrence and Recurrence of Hepatocellular Carcinoma after Direct-Acting Antiviral Therapy for Hepatitis C2023
- Author(s)
  Kawagishi Naoki、Suda Goki、Yamamoto Yoshiya、Baba Masaru、Furuya Ken、Maehara Osamu、Ohnishi Shunsuke、Yoshida Sonoe、Fu Qingjie、Yang Zijian、Hosoda Shunichi、Tokuchi Yoshimasa、Kitagataya Takashi、Ohara Masatsugu、Suzuki Kazuharu、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 1 Pages: 181-181
- DOI
  10.3390/v15010181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08046, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-23K24311
[Journal Article] Neutrophil gelatinase-associated lipocalin predicts the efficacy of tolvaptan for ascites in patients with liver cirrhosis2023
- Author(s)
  Nakai Masato、Morikawa Kenichi、Sasaki Takashi、Kohya Risako、Yoshida Sonoe、Hosoda Shunichi、Kubo Akinori、Tokuchi Yoshimasa、Kitagataya Takashi、Yamada Ren、Ohara Masatsugu、Sho Takuya、Suda Goki、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 58 Issue: 7 Pages: 656-667
- DOI
  10.1007/s00535-023-01993-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07953
[Journal Article] Potential Correlation between Changes in Serum FGF21 Levels and Lenvatinib-Induced Appetite Loss in Patients with Unresectable Hepatocellular Carcinoma2023
- Author(s)
  Kohya Risako、Suda Goki、Kawagishi Naoki、et.al.,
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 12 Pages: 3257-3257
- DOI
  10.3390/cancers15123257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14998, KAKENHI-PROJECT-23K14999, KAKENHI-PROJECT-22K08023, KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-23K24311
[Journal Article] Coexistence of muscle atrophy and high subcutaneous adipose tissue radiodensity predicts poor prognosis in hepatocellular carcinoma2023
- Author(s)
  Ohara Masatsugu、Suda Goki、Kohya Risako、Sasaki Takashi、Yoda Tomoka、Yoshida Sonoe、Fu Qingjie、Yang Zijian、Hosoda Shunichi、Maehara Osamu、Ohnishi Shunsuke、Tokuchi Yoshimasa、Kitagataya Takashi、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 10 Pages: 1-10
- DOI
  10.3389/fnut.2023.1272728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16008, KAKENHI-PROJECT-23K14998, KAKENHI-PROJECT-23K14999, KAKENHI-PROJECT-22K08023, KAKENHI-PROJECT-22K08046, KAKENHI-PROJECT-21K07953
[Journal Article] Simultaneous determination of heparan sulfate, chondroitin/dermatan sulfates, and hyaluronan glycosaminoglycan disaccharides by high-performance liquid chromatography using a reverse-phase column with adamantyl groups2023
- Author(s)
  Hanamatsu Hisatoshi、Makino Satoshi、Ohara Masatsugu、Suda Goki、Yokota Ikuko、Nishihara Shoko、Sakamoto Naoya、Furukawa Jun-ichi
- Journal Title
  
  Journal of Chromatography A
  
  Volume: 1689 Pages: 463748-463748
- DOI
  10.1016/j.chroma.2022.463748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24759, KAKENHI-PROJECT-23K24311
[Journal Article] Hepatitis C virus eradication by direct‐acting antivirals causes a simultaneous increase in the prevalence of fatty liver and hyper low‐density lipoprotein cholesterolemia without an increase in body weight2023
- Author(s)
  Tokuchi Yoshimasa、Sho Takuya et al.,
- Journal Title
  
  Hepatology Research
  
  Volume: in press Issue: 7 Pages: 595-606
- DOI
  10.1111/hepr.13899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-22K08046, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-23K24311
[Journal Article] Effect of switching from tenofovir disoproxil fumarate to tenofovir alafenamide on lipid profiles in patients with hepatitis B2022
- Author(s)
  Suzuki Kazuharu、Suda Goki、Yamamoto Yoshiya、Abiko Satoshi、Kinoshita Kenji、Miyamoto Shuichi、Sugiura Ryo、Kimura Megumi、Maehara Osamu、Yamada Ren、Kitagataya Takashi、Shigesawa Taku、Ohara Masatsugu、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 1 Pages: 261760-261760
- DOI
  10.1371/journal.pone.0261760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371
[Journal Article] Small-molecule inhibitor cocktail promotes the proliferation of pre-existing liver progenitor cells2022
- Author(s)
  Fu Qingjie、Ohnishi Shunsuke、Suda Goki、Sakamoto Naoya
- Journal Title
  
  Stem Cell Reports
  
  Volume: 17 Issue: 7 Pages: 1589-1603
- DOI
  10.1016/j.stemcr.2022.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24311
[Journal Article] Prediction of hepatocellular carcinoma using age and liver stiffness on transient elastography after hepatitis C virus eradication2022
- Author(s)
  Nakai Masato、Yamamoto Yoshiya、Baba Masaru、Suda Goki、Kubo Akinori、Tokuchi Yoshimasa、Kitagataya Takashi、Yamada Ren、Shigesawa Taku、Suzuki Kazuharu、Nakamura Akihisa、Sho Takuya、Morikawa Kenichi、Ogawa Koji、Furuya Ken、Sakamoto Naoya
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1449-1449
- DOI
  10.1038/s41598-022-05492-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-23K24311
[Journal Article] The potential of soluble CD14 in discriminating nonalcoholic steatohepatitis from nonalcoholic fatty liver disease2022
- Author(s)
  Nakamura Akihisa、Yamamoto Koji、Sakamoto Naoya et al.
- Journal Title
  
  Hepatology Research
  
  Volume: - Issue: 6 Pages: 508-521
- DOI
  10.1111/hepr.13757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-23K24311
[Journal Article] Changes in Serum Growth Factors during Lenvatinib Predict the Post Progressive Survival in Patients with Unresectable Hepatocellular Carcinoma2022
- Author(s)
  Yang Zijian、Suda Goki、et al.,
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 1 Pages: 232-232
- DOI
  10.3390/cancers14010232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-20K17039, KAKENHI-PROJECT-23K24311
[Journal Article] Baseline serum angiopoietin-2 and VEGF levels predict the deterioration of the liver functional reserve during lenvatinib treatment for hepatocellular carcinoma2021
- Author(s)
  Shigesawa T, Suda G, Kimura M, Maehara O, Tokuchi Y, Kubo A, Yamada R, Furuya K, Baba M, Kitagataya T, Suzuki K, Ohara M, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N.
- Journal Title
  
  PLoS One
  
  Volume: 16(3) Issue: 3 Pages: e0247728-e0247728
- DOI
  10.1371/journal.pone.0247728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-20K17039, KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630
[Journal Article] FGFR2 maintains cancer cell differentiation via AKT signaling in esophageal squamous cell carcinoma2021
- Author(s)
  Maehara Osamu、Suda Goki、Natsuizaka Mitsuteru、Shigesawa Taku、Kanbe Gouki、Kimura Megumi、Sugiyama Masaya、Mizokami Masashi、Nakai Masato、Sho Takuya、Morikawa Kenichi、Ogawa Koji、Ohashi Shinya、Kagawa Shingo、Kinugasa Hideaki、Naganuma Seiji、Okubo Naoto、Ohnishi Shunsuke、Takeda Hiroshi、Sakamoto Naoya
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 22 Issue: 5-6 Pages: 372-380
- DOI
  10.1080/15384047.2021.1939638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-20K17039
[Journal Article] Frequency and Characteristics of Overestimated Renal Function in Japanese Patients with Chronic Liver Disease and Its Relation to Sarcopenia2021
- Author(s)
  Yoshida Sonoe、Suda Goki、et al.,
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 7 Pages: 2415-2415
- DOI
  10.3390/nu13072415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K08371
[Journal Article] Tenofovir-disoproxil-fumarate modulates lipid metabolism via hepatic CD36/PPAR-alpha activation in hepatitis B virus infection2021
- Author(s)
  Suzuki K, Suda G, Yamamoto Y, Furuya K, Baba M, Nakamura A, Miyoshi H, Kimura M, Maehara O, Yamada R, Kitagataya T, Yamamoto K, Shigesawa T, Nakamura A, Ohara M, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Ohnishi S, Sakamoto N
- Journal Title
  
  J Gastroenterol.
  
  Volume: 56 Issue: 2 Pages: 168-180
- DOI
  10.1007/s00535-020-01750-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-19H03630
[Journal Article] Baseline elevated serum angiopoietin-2 predicts long-term non-regression of liver fibrosis after direct-acting antiviral therapy for hepatitis C2021
- Author(s)
  Kawagishi Naoki、Suda Goki、Kimura Megumi、Maehara Osamu、Yamada Ren、Tokuchi Yoshimasa、Kubo Akinori、Kitagataya Takashi、Shigesawa Taku、Suzuki Kazuharu、Ohara Masatsugu、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Kudo Yusuke、Nishida Mutsumi、Sakamoto Naoya
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 9207-9207
- DOI
  10.1038/s41598-021-88632-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-20K17008
[Journal Article] Prospect of lenvatinib for unresectable hepatocellular carcinoma in the new era of systemic chemotherapy2021
- Author(s)
  Sho Takuya、Morikawa Kenichi、Kubo Akinori、Tokuchi Yoshimasa、Kitagataya Takashi、Yamada Ren、Shigesawa Taku、Kimura Mugumi、Nakai Masato、Suda Goki、Natsuizaka Mitsuteru、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  World Journal of Gastrointestinal Oncology
  
  Volume: 13 Issue: 12 Pages: 2076-2087
- DOI
  10.4251/wjgo.v13.i12.2076
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-21K07953
[Journal Article] Recent advances in the treatment of hepatitis C virus infection for special populations and remaining problems2021
- Author(s)
  Suda G, Sakamoto N
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: in press Issue: 5 Pages: 1152-1158
- DOI
  10.1111/jgh.15189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458
[Journal Article] Successful treatment by on-demand glecaprevir and pibrentasvir for hepatitis C flare during R-CHOP in patients with diffuse large B-cell lymphoma: a case report2021
- Author(s)
  Umemura Machiko、Suda Goki、Tsukamoto Shihori、Ebata Ko、Takahash Shinjiro、Sasaki Takashi、Nakajima Sae、Hirata Koji、Ozasa Mariko、Takano Masatoshi、Katagiri Masaki、Sakamoto Naoya
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 21 Issue: 1
- DOI
  10.1186/s12879-021-06091-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458
[Journal Article] Genomic profiling of intestinal/mixed‐type superficial non‐ampullary duodenal epithelial tumors2021
- Author(s)
  Miyamoto Shuichi、Suda Goki、Ishikawa Marin、Hayashi Hideyuki、Nimura Satoshi、Matsuno Yoshihiro、Mori Ryo、Tanishima Shigeki、Kudo Takahiko、Takagi Tomofumi、Yamamoto Yoshiya、Ono Shoko、Shimizu Yuichi、Sakamoto Naoya
- Journal Title
  
  JGH Open
  
  Volume: 5 Issue: 9 Pages: 1071-1077
- DOI
  10.1002/jgh3.12632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458
[Journal Article] Changes in the estimated renal function after hepatitis C virus eradication with direct-acting antiviral agents: Impact of changes in skeletal muscle mass2021
- Author(s)
  Tokuchi Y, Suda G, Kimura M, Maehara O, Kitagataya T, Ohara M, Yamada R, Shigesawa T, Suzuki K, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N.
- Journal Title
  
  J Viral Hepat.
  
  Volume: in press Issue: 5 Pages: 755-763
- DOI
  10.1111/jvh.13484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-20K17008
[Journal Article] Possible correlation between increased serum free carnitine levels and increased skeletal muscle mass following HCV eradication by direct acting antivirals2021
- Author(s)
  Tokuchi Yoshimasa、Suda Goki、et al.,
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16616-16616
- DOI
  10.1038/s41598-021-96203-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371
[Journal Article] Characteristics and Lenvatinib Treatment Response of Unresectable Hepatocellular Carcinoma with Iso-High Intensity in the Hepatobiliary Phase of EOB-MRI2021
- Author(s)
  Kubo Akinori、Suda Goki、Kimura Megumi、Maehara Osamu、Tokuchi Yoshimasa、Kitagataya Takashi、Ohara Masatsugu、Yamada Ren、Shigesawa Taku、Suzuki Kazuharu、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Ohnishi Shunsuke、Sakamoto Naoya
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 14 Pages: 3633-3633
- DOI
  10.3390/cancers13143633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-21K07953, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-20K17039
[Journal Article] Serum fatty acid-binding protein 5 is a significant factor in hepatocellular carcinoma progression independent of tissue expression level2021
- Author(s)
  Ohira Masafumi、Yokoo Hideki、Ogawa Koji、Fukai Moto、Kamiyama Toshiya、Sakamoto Naoya、Taketomi Akinobu
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 6 Pages: 794-803
- DOI
  10.1093/carcin/bgab025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08298
[Journal Article] Analysis of the optimal psoas muscle mass index cut-off values, as measured by computed tomography, for the diagnosis of loss of skeletal muscle mass in Japanese people.2020
- Author(s)
  Ohara M, Suda G, Kimura M, Maehara O, Shimazaki T, Shigesawa T, Suzuki K, Nakamura A, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Kobayashi T, Uebayashi M, Takagi R, Yokota I, Shimamura T, Sakamoto N.
- Journal Title
  
  Hepatol Res
  
  Volume: in press Issue: 6 Pages: 715-725
- DOI
  10.1111/hepr.13499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371
[Journal Article] High serum angiopoietin‐2 level predicts non‐regression of liver stiffness measurement‐based liver fibrosis stage after direct‐acting antiviral therapy for hepatitis C2020
- Author(s)
  Kawagishi Naoki、Suda Goki、Kimura Megumi、Maehara Osamu、Shimazaki Tomoe、Yamada Ren、Kitagataya Takashi、Shigesawa Taku、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Umemura Machiko、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Kudo Yusuke、Nishida Mutsumi、Sakamoto Naoya
- Journal Title
  
  Hepatology Research
  
  Volume: in press Issue: 6 Pages: 671-681
- DOI
  10.1111/hepr.13490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07959, KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K21592, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-19H03630
[Journal Article] Durable response without recurrence to Tolvaptan improves long-term survival2020
- Author(s)
  Nakai M, Suda G, Kubo A, Tokuchi Y, Kitagataya T, Yamada R, Shigesawa T, Suzuki K, Nakamura A, Kawagishi N, Ohara M, Umemura M, Sho T, Morikawa K, Ogawa K, Sakamoto N.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 55 Issue: 12 Pages: 1150-1161
- DOI
  10.1007/s00535-020-01721-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371
[Journal Article] Lenvatinib suppresses cancer stem-like cells in HCC by inhibiting FGFR1-3 signaling, but not FGFR4 signaling2020
- Author(s)
  Shigesawa Taku、Morikawa Kenichi et al.
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 1 Pages: 58-69
- DOI
  10.1093/carcin/bgaa049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-20K17039, KAKENHI-PROJECT-19H03630
[Journal Article] Baseline angiopoietin‐2 and FGF19 levels predict treatment response in patients receiving multikinase inhibitors for hepatocellular carcinoma2020
- Author(s)
  Shigesawa Taku、Suda Goki、Kimura Megumi、Shimazaki Tomoe、Maehara Osamu、Yamada Ren、Kitagataya Takashi、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Umemura Machiko、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  JGH Open
  
  Volume: 4 Issue: 5 Pages: 880-888
- DOI
  10.1002/jgh3.12339
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08371, KAKENHI-PROJECT-20K17008, KAKENHI-PROJECT-19H03630
[Journal Article] Tri-antennary tri-sialylated mono-fucosylated glycan of alpha-1 antitrypsin as a non-invasive biomarker for non-alcoholic steatohepatitis: a novel glycobiomarker for non-alcoholic steatohepatitis2020
- Author(s)
  Ogawa Koji、Kobayashi Takashi、Furukawa Jun-ichi、Hanamatsu Hisatoshi、Nakamura Akihisa、Suzuki Kazuharu、Kawagishi Naoki、Ohara Masatsugu、Umemura Machiko、Nakai Masato、Sho Takuya、Suda Goki、Morikawa Kenichi、Sakamoto Naoya et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 321-321
- DOI
  10.1038/s41598-019-56947-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-20K21592
[Journal Article] Time-dependent changes in the seroprevalence of COVID-19 in asymptomatic liver disease outpatients in an area in Japan undergoing a second wave of COVID-192020
- Author(s)
  Suda G, Ogawa K, Kimura M, Maehara O, Kitagataya T, Ohara M, Tokuchi Y, Kubo A, Yamada R, Shigesawa T, Suzuki K, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Sakamoto N.
- Journal Title
  
  Hepatol Res.
  
  Volume: 5- Issue: 10 Pages: 1196-1200
- DOI
  10.1111/hepr.13551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08298, KAKENHI-PROJECT-20K08371
[Journal Article] Prevalence, clinical course, and predictive factors of immune checkpoint inhibitor monotherapy-associated hepatitis in Japan.2020
- Author(s)
  Kitagataya T, Suda G, Nagashima K, Katsurada T, Yamamoto K, Kimura M, Maehara O, Yamada R, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Umemura M, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Ohnishi S, Komatsu Y, Hata H, Takeuchi S, Abe T, Sakakibara-Konishi J, Teshima T, Homma A, Sakamoto N.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: in press Issue: 10 Pages: 1782-1788
- DOI
  10.1111/jgh.15041
- NAID
  120007160309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-20K08298
[Journal Article] Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues2019
- Author(s)
  Hanamatsu Hisatoshi、Nishikaze Takashi、Tsumoto Hiroki、Ogawa Koji、Kobayashi Takashi、Yokota Ikuko、Morikawa Kenichi、Suda Goki、Sho Takuya、Nakai Masato、Miura Nobuaki、Higashino Kenichi、Sekiya Sadanori、Iwamoto Shinichi、Miura Yuri、Furukawa Jun-ichi、Tanaka Koichi、Sakamoto Naoya
- Journal Title
  
  Analytical Chemistry
  
  Volume: 91 Issue: 21 Pages: 13343-13348
- DOI
  10.1021/acs.analchem.9b03617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07025, KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-19K15597, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-16K19324
[Journal Article] Effects of resistance-associated variants in genotype 2 hepatitis C virus on viral replication and susceptibility to antihepatitis C virus drugs.2019
- Author(s)
  Suda G, Kimura M, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Kawagishi N, Nakai M, Sho T, Maehara O, Shimazaki T, Morikawa K, Natsuizaka M, Ogawa K, Sakamoto N.
- Journal Title
  
  Hepatol Res
  
  Volume: 49 Issue: 11 Pages: 1275-1285
- DOI
  10.1111/hepr.13401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08458, KAKENHI-PROJECT-17K09400
[Journal Article] Correlation between Liver Elasticity by Ultrasound Elastography and Liver Functional Reserve2019
- Author(s)
  Sugiura Ryo、Kuwatani Masaki、Nishida Mutsumi、Hirata Koji、Sano Itsuki、Kato Shin、Kawakubo Kazumichi、Nakai Masato、Sho Takuya、Suda Goki、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya
- Journal Title
  
  Ultrasound in Medicine & Biology
  
  Volume: 45 Issue: 10 Pages: 2704-2712
- DOI
  10.1016/j.ultrasmedbio.2019.06.407
- NAID
  120006887711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400
[Journal Article] The Successful Retreatment with Glecaprevir and Pibrentasvir of Genotype 1 or 2 HCV-infected Hemodialysis Patients who Failed to Respond to NS5A and Protease Inhibitor Treatment2019
- Author(s)
  Suda Goki、Nakai Masato、Sho Takuya、Kimura Megumi、Shimazaki Tomoe、Maehara Osamu、Shigesawa Taku、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Umemura Machiko、Kawagishi Naoki、Baba Masaru、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya、for the NORTE Study Group
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 7 Pages: 943-947
- DOI
  10.2169/internalmedicine.2077-18
- NAID
  130007622183
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K09334
[Journal Article] Quantifying Protein-Specific N-Glycome Profiles by Focused Protein and Immunoprecipitation Glycomics2019
- Author(s)
  Kobayashi Takashi、Ogawa Koji、Furukawa Jun-ichi、Hanamatsu Hisatoshi、Hato Megumi、Yoshinaga Tomoyo、Morikawa Kenichi、Suda Goki、Sho Takuya、Nakai Masato、Higashino Kenichi、Numata Yoshito、Shinohara Yasuro、Sakamoto Naoya
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 18 Issue: 8 Pages: 3133-3141
- DOI
  10.1021/acs.jproteome.9b00232
- NAID
  120006876288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03630, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-16K19324
[Journal Article] Assessing the risk of hepatocellular carcinoma by combining liver stiffness and the controlled attenuation parameter2019
- Author(s)
  Izumi Takaaki、Sho Takuya、Morikawa Kenichi、Shigesawa Taku、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Kawagishi Naoki、Umemura Machiko、Shimazaki Tomoe、Kimura Megumi、Nakai Masato、Suda Goki、Natsuizaka Mitsuteru、Ogawa Koji、Kudo Yusuke、Nishida Mutsumi、Ono Kota、Baba Masaru、Furuya Ken、Sakamoto Naoya
- Journal Title
  
  Hepatology Research
  
  Volume: 49 Issue: 10 Pages: 1207-1217
- DOI
  10.1111/hepr.13391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324
[Journal Article] Entecavir treatment of hepatitis B virus‐infected patients with severe renal impairment and those on hemodialysis2019
- Author(s)
  Suzuki Kazuharu、Suda Goki、Yamamoto Yoshiya、Furuya Ken、Baba Masaru、Kimura Megumi、Maehara Osamu、Shimazaki Tomoe、Yamamoto Koji、Shigesawa Taku、Nakamura Akihisa、Ohara Masatsugu、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya、for the NORTE Study Group
- Journal Title
  
  Hepatology Research
  
  Volume: 49 Issue: 11 Pages: 1294-1304
- DOI
  10.1111/hepr.13399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324
[Journal Article] Glecaprevir and Pibrentasvir for Japanese Patients with Human Immunodeficiency Virus and Genotype 3 Hepatitis C Virus Coinfection: A Report of Three Cases2019
- Author(s)
  Sho Takuya、Suda Goki、Kimura Megumi、Shimazaki Tomoe、Maehara Osamu、Shigesawa Taku、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Umemura Machiko、Izumi Takaaki、Kawagishi Naoki、Baba Masaru、Nakai Masato、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya、for the NORTE Study Group
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 6 Pages: 797-802
- DOI
  10.2169/internalmedicine.1856-18
- NAID
  130007611402
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-03-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324
[Journal Article] Safety and efficacy of sofosbuvir and ribavirin for genotype 2 hepatitis C Japanese patients with renal dysfunction2018
- Author(s)
  Sho T, Suda G,, Nagasaka A, Yamamoto Y, Furuya K, Kumagai K, Uebayashi M, Terashita K, Kobayashi T, Tsunematsu I, Onodera M, Meguro T, Kimura M, Ito J, Umemura M, Izumi T, Kawagishi N, Ohara M, Ono Y, Nakai M, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N
- Journal Title
  
  Heptology Research
  
  Volume: in press Issue: 7 Pages: 529-538
- DOI
  10.1111/hepr.13056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K15420
[Journal Article] Evaluation of amnion-derived mesenchymal stem cells for treatment-resistant moderate Crohn's disease: study protocol for a phase I/II, dual-centre, open-label, uncontrolled, dose-response trial.2018
- Author(s)
  Otagiri S, Ohnishi S, Miura A, Hayashi H, Kumagai I, Ito YM, Katsurada T, Nakamura S, Okamoto R, Yamahara K, Cho KY, Isoe T, Sato N, Sakamoto N
- Journal Title
  
  BMJ Open Gastroenterol
  
  Volume: 5 Issue: 1 Pages: e000206-e000206
- DOI
  10.1136/bmjgast-2018-000206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05282
[Journal Article] Regulation of interferon signaling and HCV-RNA replication by extracellular matrix.2018
- Author(s)
  Kuwashiro T, Iwane S, Jinghe X, Matsuhashi S, Eguchi Y, Anzai K, Fujimoto K, Mizuta T, Sakamoto N, Ikeda M, Kato N, Ozaki I.
- Journal Title
  
  Int J Mol Med
  
  Volume: 42 Pages: 957-965
- DOI
  10.3892/ijmm.2018.3693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05196, KAKENHI-PROJECT-16H05282
[Journal Article] Cecum ulcer is a reliable endoscopic finding in cytomegalovirus colitis concomitant with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation2018
- Author(s)
  Matsuda Kana、Ono Shoko、Ishikawa Marin、Miyamoto Shuichi、Abiko Satoshi、Tsuda Momoko、Yamamoto Keiko、Kudo Takahiko、Shimizu Yuichi、Hayase Eiko、Hashimoto Daigo、Teshima Takanori、Matsuno Yoshihiro、Sakamoto Naoya
- Journal Title
  
  Annals of Hematology
  
  Volume: 97 Issue: 5 Pages: 877-883
- DOI
  10.1007/s00277-018-3241-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09945, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17H04206
[Journal Article] Liver steatosis and dyslipidemia after HCV eradication by direct acting antiviral agents are synergistic risks of atherosclerosis2018
- Author(s)
  Kawagishi Naoki、Suda Goki、Nakamura Akinobu、Kimura Megumi、Maehara Osamu、Suzuki Kazuharu、Nakamura Akihisa、Ohara Masatsugu、Izumi Takaaki、Umemura Machiko、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ogawa Koji、Kudo Yusuke、Nishida Mutsumi、Miyoshi Hideaki、Sakamoto Naoya
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 12 Pages: 615-620
- DOI
  10.1371/journal.pone.0209615
- NAID
  120006866533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19324, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17J00434, KAKENHI-PROJECT-16K09334
[Journal Article] Safety and efficacy of elbasvir and grazoprevir in Japanese hemodialysis patients with genotype 1b hepatitis C virus infection2018
- Author(s)
  Suda Goki、Morikawa Kenichi、Ogawa Koji、Sakamoto Naoya、他
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Issue: 1 Pages: 78-86
- DOI
  10.1007/s00535-018-1495-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324
[Journal Article] Mesenchymal stem cell therapy for acute and chronic pancreatitis.2018
- Author(s)
  Kawakubo K, Ohnishi S, Kuwatani M, Sakamoto N
- Journal Title
  
  J Gastroenterol
  
  Volume: 53 Issue: 1 Pages: 1-5
- DOI
  10.1007/s00535-017-1363-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05282
[Journal Article] Increased serum C-reactive protein and decreased urinary aquaporin 2 levels are predictive of the efficacy of tolvaptan in patients with liver cirrhosis2018
- Author(s)
  3.Nakai M, Ogawa K, Takeda R, Ohara M, Kawagishi N, Izumi T, Umemura M, Ito J, Sho T, Suda G, Morikawa K, Sakamoto N
- Journal Title
  
  Hepatolgy Research
  
  Volume: in press Issue: 3
- DOI
  10.1111/hepr.12988
- NAID
  120006551584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324, KAKENHI-PROJECT-16H05282
[Journal Article] Palmitoylethanolamide Ameliorates Carbon Tetrachloride-Induced Liver Fibrosis in Rats.2018
- Author(s)
  Ohara M, Ohnishi S, Hosono H, Yamamoto K, Fu Q, Maehara O, Suda G, Sakamoto N
- Journal Title
  
  Front Pharmacol
  
  Volume: 9 Pages: 709-709
- DOI
  10.3389/fphar.2018.00709
- NAID
  120006522665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17J00434
[Journal Article] Treatment of hepatitis C in special populations.2018
- Author(s)
  Suda G, Ogawa K, Morikawa K, Sakamoto N
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: in press Issue: 5 Pages: 591-605
- DOI
  10.1007/s00535-017-1427-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-15K08980
[Journal Article] Sialic Acid Linkage Specific Derivatization of Glycosphingolipid Glycans by Ring-Opening Aminolysis of Lactones.2018
- Author(s)
  Hanamatsu H, Nishikaze T, Miura N, Piao J, Okada K, Sekiya S, Iwamoto S, Sakamoto N, Tanaka K, Furukawa JI
- Journal Title
  
  Anal Chem
  
  Volume: 90 Issue: 22 Pages: 13193-13199
- DOI
  10.1021/acs.analchem.8b02775
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16K05804
[Journal Article] Conditioned Medium from Human Amnion-Derived Mesenchymal Stem Cells Regulates Activation of Primary Hepatic Stellate Cells.2018
- Author(s)
  Fu Q, Ohnishi S, Sakamoto N
- Journal Title
  
  Stem Cells Int
  
  Volume: 20 Pages: 4898152-4898152
- DOI
  10.1155/2018/4898152
- NAID
  120006541895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05282
[Journal Article] L-Carnitine Suppresses Loss of Skeletal Muscle Mass in Patients With Liver Cirrhosis2018
- Author(s)
  Ohara Masatsugu、Ogawa Koji、Suda Goki、Kimura Megumi、Maehara Osamu、Shimazaki Tomoe、Suzuki Kazuharu、Nakamura Akihisa、Umemura Machiko、Izumi Takaaki、Kawagishi Naoki、Nakai Masato、Sho Takuya、Natsuizaka Mitsuteru、Morikawa Kenichi、Ohnishi Shunsuke、Sakamoto Naoya
- Journal Title
  
  Hepatology Communications
  
  Volume: 2 Issue: 8 Pages: 906-918
- DOI
  10.1002/hep4.1207
- NAID
  120006585791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324, KAKENHI-PROJECT-17J00434, KAKENHI-PROJECT-16K09334
[Journal Article] Safety and efficacy of elbasvir/grazoprevir for the treatment of chronic hepatitis C: current evidence2018
- Author(s)
  Morikawa Kenichi、Nakamura Akihisa、Shimazaki Tomoe、Sakamoto Naoya
- Journal Title
  
  Drug Design, Development and Therapy
  
  Volume: Volume 12 Pages: 2749-2756
- DOI
  10.2147/dddt.s133697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09400
[Journal Article] Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats2018
- Author(s)
  Ohara Masatsugu、Ohnishi Shunsuke、Hosono Hidetaka、Yamamoto Koji、Yuyama Kohei、Nakamura Hideki、Fu Qingjie、Maehara Osamu、Suda Goki、Sakamoto Naoya
- Journal Title
  
  Stem Cells International
  
  Volume: 2018 Pages: 1-15
- DOI
  10.1155/2018/3212643
- NAID
  120006585982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06456, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17J00434, KAKENHI-PROJECT-16K09334
[Journal Article] Macrophage-Derived Extracellular Vesicles Induce Long-Lasting Immunity Against Hepatitis C Virus Which Is Blunted by Polyunsaturated Fatty Acids.2018
- Author(s)
  Cai C, Koch B, Morikawa K, Suda G, Sakamoto N, Rueschenbaum S, Akhras S, Dietz J, Hildt E, Zeuzem S, Welsch C, Lange CM
- Journal Title
  
  Front Immunol
  
  Volume: 9 Pages: 723-723
- DOI
  10.3389/fimmu.2018.00723
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05282
[Journal Article] Conditioned Medium Obtained from Amnion-Derived Mesenchymal Stem Cell Culture Prevents Activation of Keloid Fibroblasts.2018
- Author(s)
  Sato C, Yamamoto Y, Funayama E, Furukawa H, Oyama A, Murao N, Hosono H, Kawakubo K, Sakamoto N, Ohnishi S
- Journal Title
  
  Plast Reconstr Surg
  
  Volume: 141 Issue: 2 Pages: 390-398
- DOI
  10.1097/prs.0000000000004068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19530, KAKENHI-PROJECT-16H05282
[Journal Article] Increased serum C-reactive protein and decreased urinary aquaporin 2 levels are predictive of the efficacy of tolvaptan in patients with liver cirrhosis.2018
- Author(s)
  3.Nakai M, Ogawa K, Takeda R, Ohara M, Kawagishi N, Izumi T, Umemura M, Ito J, Sho T, Suda G, Morikawa K, Sakamoto N
- Journal Title
  
  Hepatology Research
  
  Volume: in press
- NAID
  120006551584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08980
[Journal Article] Effects of human amnion-derived mesenchymal stem cells and conditioned medium in rats with sclerosing cholangitis.2018
- Author(s)
  Sugiura R, Ohnishi S, Ohara M, Ishikawa M, Miyamoto S, Onishi R, Yamamoto K, Kawakubo K, Kuwatani M, Sakamoto N
- Journal Title
  
  Am J Transl Res
  
  Volume: 10 Pages: 2102-2114
- NAID
  120006528265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05282
[Journal Article] Hepatitis B virus X protein impairs α-interferon signaling via up-regulation of suppressor of cytokine signaling 3 and protein phosphatase 2A.2017
- Author(s)
  Tsunematsu S, Suda G, Yamasaki K, Kimura M, Izumi T, Umemura M, Ito J, Sato F, Nakai M, Sho T, Morikawa K, Ogawa K, Tanaka Y, Watashi K, Wakita T, Sakamoto N
- Journal Title
  
  J Med Virol
  
  Volume: 89 Issue: 2 Pages: 267-275
- DOI
  10.1002/jmv.24643
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16K15420, KAKENHI-PROJECT-26460565
[Journal Article] Interferon-free therapy with sofosbuvir plus ribavirin for successful treatment of genotype 2 hepatitis C virus with lichen planus: a case report2017
- Author(s)
  Yoshikawa Ayumu、Terashita Katsumi、Morikawa Kenichi、Matsuda Soichiro、Yamamura Takahiro、Sarashina Koichiro、Nakano Shintaro、Kobayashi Yoshimitsu、Sogabe Susumu、Takahashi Kazuhiro、Haba Shin、Oda Hisashi、Takahashi Tatsuro、Miyagishima Takuto、Sakamoto Naoya
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: 10 Issue: 3 Pages: 270-273
- DOI
  10.1007/s12328-017-0742-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400
[Journal Article] Hepatitis B virus reactivation during hepatitis C direct-acting antiviral therapy in patients with previous HBV infection2017
- Author(s)
  Kawagishi N, Suda G, Onozawa M, Kimura M, Maehara O, Ito J, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N
- Journal Title
  
  Journal of Hepatology
  
  Volume: 67 Issue: 5 Pages: 1098-1106
- DOI
  10.1016/j.jhep.2017.04.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-17J00434
[Journal Article] Add-on effects of fluvastatin in simeprevir/pegylated-interferon/ribavirin combination therapy for patients with genotype 1 hepatitis C virus infection: A randomized controlled study2017
- Author(s)
  5.Suda G, Ito J, Nagasaka A, Yamamoto Y, Furuya K, Okamoto M, Terashita K, Kobayashi T, Tsunematsu I, Yoshida J, Meguro T, Ohara M, Kawagishi N, Kimura M, Umemura M, Izumi T, Tsukuda Y, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N
- Journal Title
  
  Hepatology Research
  
  Volume: 48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08980
[Journal Article] Retreatment with sofosbuvir, ledipasvir, and add-on ribavirin for patients who failed daclatasvir and asunaprevir combination therapy2017
- Author(s)
  Suda G, Ogawa K, Yamamoto Y, Katagiri M, Furuya K, Kumagai K, Konno J, Kimura M, Kawagishi N, Ohara M, Umemura M, Ito J, Izumi T, Nakai M, Sho T, Natsuizaka M, Morikawa K, Tsubota A, Shimada N, Iio E, Tanaka Y, Sakamoto N; NORTE Study Group.
- Journal Title
  
  J Gastroenterol
  
  Volume: 印刷中 Issue: 10 Pages: 1122-1129
- DOI
  10.1007/s00535-017-1328-z
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-15K06810, KAKENHI-PROJECT-16K15420
[Journal Article] Retinoid derivative Tp80 exhibits anti-hepatitis C virus activity through restoration of GI-GPx expression.2017
- Author(s)
  Ngoc NB, Okuno Y, Ajiro M, Iida K, Denawa M, Yamamoto M, Sakamoto N, Kagechika H, Hagiwara M
- Journal Title
  
  J Med Virol
  
  Volume: Epub ahead of print Issue: 7 Pages: 1224-1234
- DOI
  10.1002/jmv.24739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-15H05721, KAKENHI-PROJECT-16K15420
[Journal Article] Brain micro-inflammation at specific vessels dysregulates organ-homeostasis via the activation of a new neural circuit.2017
- Author(s)
  Arima, Y., T. Ohki, N. Nishikawa, K. Higuchi, M. Ota, Y. Tanaka, J. Nio-Kobayashi, M. Elfeky, R. Sakai, Y. Mori, T. Kawamoto, A. Stofkova, Y. Sakashita, Y. Morimoto, M. Kuwatani, T. Iwanaga, Y. Yoshioka, N. Sakamoto, A. Yoshimura, M. Takiguchi, S. Sakoda, M. Prinz, D. Kamimura, M. Murakami.
- Journal Title
  
  eLife
  
  Volume: 6:e25517 Pages: 1-27
- DOI
  10.7554/elife.25517
- NAID
  120006360081
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19537, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-15H04741, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-15K08518, KAKENHI-PROJECT-17K15712
[Journal Article] Identification of novel serum autoantibodies against EID3 in non-functional pancreatic neuroendocrine tumors.2017
- Author(s)
  Hontani K, Tsuchikawa T, Hiwasa T, Nakamura T, Ueno T, Kushibiki T, Takahashi M, Inoko K, Takano H, Takeuchi S, Dosaka-Akita H, Kuwatani M, Sakamoto N, Hatanaka Y, Mitsuhashi T, Shimada H, Shichinohe T, Hirano S.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 63 Pages: 106206-106221
- DOI
  10.18632/oncotarget.22175
- NAID
  120006416017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08684, KAKENHI-PROJECT-16K10520, KAKENHI-PROJECT-16H05282
[Journal Article] Comparing the risk of hepatitis B virus reactivation between direct-acting antiviral therapies and interferon-based therapies for hepatitis C2017
- Author(s)
  Kawagishi N.、Suda G.、Onozawa M.、Kimura M.、Maehara O.、Ohara M.、Izumi T.、Umemura M.、Ito J.、Nakai M.、Sho T.、Natsuizaka M.、Morikawa K.、Ogawa K.、Sakamoto N.
- Journal Title
  
  J Viral Hepat.
  
  Volume: 24 Issue: 12 Pages: 1098-1106
- DOI
  10.1111/jvh.12737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K19324, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17J00434, KAKENHI-PROJECT-16K15420
[Journal Article] Fibroblast growth factor-2-mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma2017
- Author(s)
  Osamu Maehara, Goki Suda et al.
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Issue: 11 Pages: 1073-1083
- DOI
  10.1093/carcin/bgx095
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-17J00434, KAKENHI-PROJECT-15K08943
[Journal Article] The Paradoxical Effects of Different Hepatitis C Viral Loads on Host DNA Damage and Repair Abilities.2017
- Author(s)
  Wang SC, Lai KR, Li CY, Chiang CS, Yu GY, Sakamoto N, Tu WY, Hsieh MH, Huang JF, Chuang WL, Dai CY, Yu ML
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 1 Pages: 1-1
- DOI
  10.1371/journal.pone.0164281
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16K15420
[Journal Article] Safety and efficacy of daclatasvir and asunaprevir in hepatitis C virus infected patients with renal impairment2017
- Author(s)
  Suda G, Nagasaka A, Yamamoto Y, Furuya K, Kumagai K, Kudo M, Terashita K, Kobayashi T, Tsunematsu I, Yoshida J, Meguro T, Kimura M, Ito J, Umemura M, Izumi T, Tsunematsu S, Sato F, Tsukuda Y, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N; NORTE Study Group.
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 11 Pages: 1127-1136
- DOI
  10.1111/hepr.12851
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16K15420
[Journal Article] A Phase I Study of Combination Therapy with Sorafenib and 5-Fluorouracil in Patients with Advanced Hepatocellular Carcinoma2017
- Author(s)
  Sho Takuya、Nakanishi Mitsuru、Morikawa Kenichi、Ohara Masatsugu、Kawagishi Naoki、Izumi Takaaki、Umemura Machiko、Ito Jun、Nakai Masato、Suda Goki、Ogawa Koji、Chuma Makoto、Meguro Takashi、Nakamura Michio、Nagasaka Atsushi、Horimoto Hiromasa、Yamamoto Yoshiya、Sakamoto Naoya
- Journal Title
  
  Drugs R D.
  
  Volume: 17 Issue: 3 Pages: 381-388
- DOI
  10.1007/s40268-017-0187-7
- NAID
  120006369333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09400
[Journal Article] Genome-wide Association Study Identifies TLL1 Variant Associated With Development of Hepatocellular Carcinoma After Eradication of Hepatitis C Virus Infection.2017
- Author(s)
  Matsuura K, Honda M, et al.
- Journal Title
  
  Gastroenterology.
  
  Volume: - Issue: 6 Pages: 1383-1394
- DOI
  10.1053/j.gastro.2017.01.041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16H05285, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K08986, KAKENHI-PROJECT-15K09006, KAKENHI-PROJECT-15K09019, KAKENHI-PROJECT-16K09335, KAKENHI-PROJECT-17K09457, KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-15K08314
[Journal Article] Daclatasvir and asunaprevir in hemodialysis patients with hepatitis C virus infection: a nationwide retrospective study in Japan2017
- Author(s)
  Suda Goki、Morikawa Kenichi、et al.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 53 Issue: 1 Pages: 119-128
- DOI
  10.1007/s00535-017-1353-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16K15420
[Journal Article] Hepatitis C virus-induced innate immune responses in human iPS cell-derived hepatocyte-like cells2017
- Author(s)
  Sakurai Fuminori、Kunito Takemaru、Takayama Kazuo、Hashimoto Rina、Tachibana Masashi、Sakamoto Naoya、Wakita Takaji、Mizuguchi Hiroyuki
- Journal Title
  
  Virus Research
  
  Volume: 242 Pages: 7-15
- DOI
  10.1016/j.virusres.2017.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09447, KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-16K15420
[Journal Article] Add-on effects of fluvastatin in simeprevir/pegylated-interferon/ribavirin combination therapy for patients with genotype 1 hepatitis C virus infection: A randomized controlled study2017
- Author(s)
  Suda Goki、Morikawa Kenichi、et al.
- Journal Title
  
  Hepatol Res.
  
  Volume: 48 Issue: 3
- DOI
  10.1111/hepr.12938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09400, KAKENHI-PROJECT-16K15420
[Journal Article] Prevalence and characteristics of naturally occurring sofosbuvir resistance-associated variants in patients with hepatitis C virus genotype 1b infection2016
- Author(s)
  Ito J, Suda G, Yamamoto Y, Nagasaka A, Furuya K, Kumagai K, Kikuchi H, Miyagishima T, Kobayashi T, Kimura M, Yamasaki K, Umemura M, Izumi T, Tsunematsu S, Sato F, Tsukuda Y, Terashita K, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto
- Journal Title
  
  Hepatol Res
  
  Volume: in press Issue: 13 Pages: 1294-1303
- DOI
  10.1111/hepr.12685
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-16K15420
[Journal Article] Viral life cycle of hepatitis B virus : host factors and druggable targets.2016
- Author(s)
  Morikawa K, Suda G, Sakamoto N
- Journal Title
  
  Hepatol Res
  
  Volume: EPub Issue: 9 Pages: 871-877
- DOI
  10.1111/hepr.12650
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-16K15420
[Journal Article] Anti-adipogenic and antiviral effects of l-carnitine on hepatitis C virus infection.2016
- Author(s)
  Tsukuda Y, Suda G, Tsunematsu S, Ito J, Sato F, Terashita K, Nakai M, Sho T, Maehara O, Shimazaki T, Kimura M, Morikawa K, Natsuizaka M, Ogawa K, Ohnishi S, Chuma M, Sakamoto N
- Journal Title
  
  J Med Virol
  
  Volume: 89 Issue: 5 Pages: 857-866
- DOI
  10.1002/jmv.24692
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05282, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08943, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-16K09334, KAKENHI-PROJECT-16K15420
[Journal Article] Efficacy and safety of daclatasvir and asunaprevir combination therapy in chronic hemodialysis patients with chronic hepatitis C.2016
- Author(s)
  Suda G, Kudo M, Nagasaka A, Furuya K, Yamamoto Y, Kobayashi T, Shinada K, Tateyama M, Konno J, Tsukuda Y, Yamasaki K, Kimura M, Umemura M, Izumi T, Tsunematsu S, Sato F, Terashita K, Nakai M, Horimoto H, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N
- Journal Title
  
  J Gastroenterol
  
  Volume: in press
- NAID
  120006313426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08980
[Journal Article] Efficacy and safety of daclatasvir and asunaprevir combination therapy in chronic hemodialysis patients with chronic hepatitis C.2016
- Author(s)
  Suda G, Kudo M, Nagasaka A, Furuya K, Yamamoto Y, Kobayashi T, Shinada K, Tateyama M, Konno J, Tsukuda Y, Yamasaki K, Kimura M, Umemura M, Izumi T, Tsunematsu S, Sato F, Terashita K, Nakai M, Horimoto H, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: EPub Issue: 7 Pages: 733-740
- DOI
  10.1007/s00535-016-1162-8
- NAID
  120006313426
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26461021, KAKENHI-PROJECT-15K08943
[Journal Article] ZEB1 expression is associated with prognosis of intrahepatic cholangiocarcinoma2016
- Author(s)
  Terashita K, Chuma M, Hatanaka Y, Hatanaka K, Mitsuhashi T, Yokoo H, Ohmura T, Ishizu H, Muraoka S, Nagasaka A, Tsuji T, Yamamoto Y, Kurauchi N, Shimoyama N, Toyoda H, Kumada T, Kaneoka Y, Maeda A, Ogawa K, Natsuizaka M, Kamachi H, Kakisaka T, Kamiyama T, Taketomi A, Matsuno Y, Sakamoto N
- Journal Title
  
  J Clin Pathol
  
  Volume: in press Issue: 7 Pages: 593-599
- DOI
  10.1136/jclinpath-2015-203115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-25460449, KAKENHI-PROJECT-24590674, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-15K08943, KAKENHI-PROJECT-16K08684
[Journal Article] Resistance Analyses of Japanese Hepatitis C-Infected Patients Receiving Sofosbuvir or Ledipasvir/Sofosbuvir Containing Regimens in Phase 3 Studies.2016
- Author(s)
  Mizokami M, Dvory-Sobol H, Izumi N, Nishiguchi S, Doehle B, Svarovskaia ES, De-Oertel S, Knox S, Brainard DM, Miller MD, Mo H, Sakamoto N, Takehara T, Omata M
- Journal Title
  
  J Viral Hepat
  
  Volume: 23 Issue: 10 Pages: 780-788
- DOI
  10.1111/jvh.12549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15420
[Journal Article] Impaired induction of interleukin 28B and expression of interferon λ 4 associated with nonresponse to interferon-based therapy in chronic hepatitis C.2015
- Author(s)
  Murakawa M, Asahina Y, Nakagawa M, Sakamoto N, Nitta S, Kusano-Kitazume A, Watanabe T, Kawai-Kitahata F, Otani S, Taniguchi M, Goto F, Nishimura-Sakurai Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590959
[Journal Article] New molecularly targeted therapies against advanced hepatocellular carcinoma: From molecular pathogenesis to clinical trials and future directions.2015
- Author(s)
  Chuma M, Terashita K, Sakamoto N
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 10
- DOI
  10.1111/hepr.12459
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26460982
[Journal Article] The JAK2 inhibitor AZD1480 inhibits hepatitis A virus replication in Huh7 cells.2015
- Author(s)
  Jiang X, Kanda T, Nakamoto S, Saito K, Nakamura M, Wu S, Haga Y, Sasaki R, Sakamoto N, Shirasawa H, Okamoto H, Yokosuka O
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 4 Pages: 908-912
- DOI
  10.1016/j.bbrc.2015.02.058
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590955, KAKENHI-PROJECT-26430155
[Journal Article] Human amnion-derived mesenchymeal stem cell transplantation ameliorates dextran sulfate sodium-induced severe colitis in rats.2015
- Author(s)
  ２．Onishi R, Ohnishi S, Higashi R, Watari M, Yamahara K, Okubo N, Nakagawa K, Katsurada T, Suda G, Natsuizaka M, Takeda H, Sakamoto N
- Journal Title
  
  Cell Transplantation
  
  Volume: Epub ahead of print
- NAID
  120005690898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] Serum granulysin levels as a predictor of serious telaprevir-induced dermatological reactions.2015
- Author(s)
  Suda G, Yamamoto Y, Nagasaka A, Furuya K, Kudo M, Chuganji Y, Tsukuda Y, Tsunematsu S, Sato F, Terasita K, Nakai M, Horimoto H, Sho T, Natsuizaka M, Ogawa K, Ohnishi S, Chuma M, Fujita Y, Abe R, Taniguchi M, Nakagawa M, Asahina Y, Sakamoto N
- Journal Title
  
  Hepatol Res
  
  Volume: 印刷中 Issue: 8 Pages: 837-45
- DOI
  10.1111/hepr.12421
- NAID
  120005820706
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860513, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-15K08980
[Journal Article] Intratumoral artery on contrast-enhanced computed tomography imaging: differentiating intrahepatic cholangiocarcinoma from poorly differentiated hepatocellular carcinoma2015
- Author(s)
  Tsunematsu S, Chuma M, Kamiyama T, Miyamoto N, Yabusaki S, Hatanaka K, Mitsuhashi T, Kamachi H, Yokoo H, Kakisaka T, Tsuruga Y, Orimo T, Wakayama K, Ito J, Sato F, Terashita K, Nakai M, Tsukuda Y, Sho T, Suda G, Morikawa K, Natsuizaka M, Nakanishi M, Ogawa K, Taketomi A, Matsuno Y, Sakamoto N
- Journal Title
  
  Abdom Imaging
  
  Volume: 40 Issue: 6 Pages: 1492-9
- DOI
  10.1007/s00261-015-0352-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-26460982, KAKENHI-PROJECT-26461021
[Journal Article] EGFR inhibitors eliminate cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition2015
- Author(s)
  １．Fumiyuki Sato, Yoshimasa Kubota, Mitsuteru Natsuizaka, Osamu Maehara, Yutaka Hatanaka, Katsuji Marukawa, Katsumi Terashita, Goki Suda, Shunsuke Ohnishi, Yuichi Shimizu, Yoshito Komatsu, Shinya Ohashi, Shingo Kagawa, Hideaki Kinugasa, Kelly Whelan, Anil Rustgi, Hiroshi Nakagawa, and Naoya Sakamoto
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] Amino acid polymorphisms in hepatitis C virus core affect infectious virus production and major histocompatibility complex class I molecule expression2015
- Author(s)
  Tasaka-Fujita M, Sugiyama N, Kang W, Masaki T, Murayama A, Yamada N, Sugiyama R, Tsukuda S, Watashi K, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 13994-14002
- DOI
  10.1038/srep13994
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09035, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-15K15285, KAKENHI-PROJECT-26860309, KAKENHI-PLANNED-24115003, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-25293169
[Journal Article] Hepatocellular carcinoma risk assessment using gadoxetic acid-enhanced hepatocyte phase magnetic resonance imaging.2015
- Author(s)
  Komatsu N, Motosugi U, Maekawa S, Shindo K, Sakamoto M, Sato M, Tatsumi A, Miura M, Amemiya F, Nakayama Y, Inoue T, Fukasawa M, Uetake T, Ohtaka M, Sato T, Asahina Y, Kurosaki M, Izumi N, Ichikawa T, Araki T, Enomoto N.
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 13 Pages: 1339-1346
- DOI
  10.1111/hepr.12309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24590965, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25670366
[Journal Article] Effects of HLA-DPB1 genotypes on chronic hepatitis B infection in Japanese individuals.2015
- Author(s)
  N. Nishida, J. Ohashi, M. Sugiyama, T. Tsuchiura, K. Yamamoto, K. Hino, M. Honda, S. Kaneko, H. Yatsuhashi, K. Koike, O. Yokosuka, E. Tanaka, A. Taketomi, M. Kurosaki, N. Izumi, N. Sakamoto, Y. Eguchi, T. Sasazuki, K. Tokunaga, and M. Mizokami
- Journal Title
  
  Tissue Antigens
  
  Volume: 5 Issue: 6 Pages: 406-412
- DOI
  10.1111/tan.12684
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-26293179, KAKENHI-PROJECT-25291103
[Journal Article] Ledipasvir and sofosbuvir fixed-dose combination with and without ribavirin for 12 weeks in treatment-naive and previously treated Japanese patients with genotype 1 hepatitis C: an open-label, randomised, phase 3 trial.2015
- Author(s)
  Mizokami M, Yokosuka O, Takehara T, Sakamoto N, Korenaga M, Mochizuki H, Nakane K, Enomoto H, Ikeda F, Yanase M, Toyoda H, Genda T, Umemura T, Yatsuhashi H, Ide T et al.
- Journal Title
  
  Lancet Infect Dis
  
  Volume: 印刷中 Issue: 6 Pages: 645-653
- DOI
  10.1016/s1473-3099(15)70099-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-26670375
[Journal Article] Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C.2015
- Author(s)
  Iio E, Matsuura K, Nishida N, Maekawa S, Enomoto N, Nakagawa M, Sakamoto N, Yatsuhashi H et al.
- Journal Title
  
  Hum Genet
  
  Volume: 134 Issue: 3 Pages: 279-289
- DOI
  10.1007/s00439-014-1520-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24390187, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590965, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26670378, KAKENHI-PROJECT-26293179
[Journal Article] Impaired induction of IL28B and expression of IFNλ4 associated with non-response to interferon-based therapy in chronic hepatitis C.2015
- Author(s)
  Murakawa M, Asahina Y, Nakagawa M, Sakamoto N, Nitta S, Kusano-Kitazume A, Watanabe T, Kawai-Kitahata F, Otani S, Taniguchi M, Goto F, Nishimura-Sakurai Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 印刷中 Issue: 6 Pages: 1075-84
- DOI
  10.1111/jgh.12902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-26460986, KAKENHI-PROJECT-26460987, KAKENHI-PROJECT-26460988, KAKENHI-PROJECT-26670375, KAKENHI-PROJECT-15K08988, KAKENHI-PROJECT-15K19316, KAKENHI-PROJECT-15K08989
[Journal Article] Intratumoral artery on contrast-enhanced computed tomography imaging: differentiating intrahepatic cholangiocarcinoma from poorly differentiated hepatocellular carcinoma2015
- Author(s)
  ３．Tsunematsu S1, Chuma M, Kamiyama T, Miyamoto N, Yabusaki S, Hatanaka K, Mitsuhashi T, Kamachi H, Yokoo H, Kakisaka T, Tsuruga Y, Orimo T, Wakayama K, Ito J, Sato F, Terashita K, Nakai M, Tsukuda Y, Sho T, Suda G, Morikawa K, Natsuizaka M, Nakanishi M, Ogawa K, Taketomi A, Matsuno Y, Sakamoto N
- Journal Title
  
  Abdom Imaging.
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] Human Amnion-derived Mesenchymal Stem Cell Transplantation Ameliorates Liver Fibrosis in Rats2015
- Author(s)
  Onishi R, Ohnishi S, Higashi R, Watari M, Yamahara K, Okubo N, Nakagawa K, Katsurada T, Suda G, Natsuizaka M, Takeda H, Sakamoto N
- Journal Title
  
  Transplant Direct
  
  Volume: 印刷中
- NAID
  120005773991
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390185
[Journal Article] A pivotal role of Krüppel-like factor 5 in regulation of cancer stem-like cells in hepatocellular carcinoma.2015
- Author(s)
  Maehara O, Sato F, Natsuizaka M, Asano A, Kubota Y, Itoh J, Tsunematsu S, Terashita K, Tsukuda Y, Nakai M, Sho T, Suda G, Morikawa K, Ogawa K, Chuma M, Nakagawa K, Ohnishi S, Komatsu Y, Whelan KA, Nakagawa H, Takeda H, Sakamoto N.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 16 Issue: 10 Pages: 14531461-14531461
- DOI
  10.1080/15384047.2015.1070992
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08943, KAKENHI-PROJECT-15K08980, KAKENHI-PROJECT-26460933, KAKENHI-PROJECT-26461021
[Journal Article] Sofosbuvir plus ribavirin in Japanese patients with chronic genotype 2 HCV infection: an open-label, phase 3 trial.2014
- Author(s)
  Omata M, Nishiguchi S, Ueno Y, Mochizuki H, Izumi N, Ikeda F, Toyoda H, Yokosuka O, Nirei K, Genda T, Umemura T, Takehara T, Sakamoto N, Nishigaki Y, Nakane K, Toda N, Ide T, Yanase M, Hino K et al.
- Journal Title
  
  J Viral Hepat
  
  Volume: 21 Issue: 11 Pages: 762-768
- DOI
  10.1111/jvh.12312
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670375
[Journal Article] Hepatosplenic Gamma-delta T-cell Lymphoma Associated with Epstein-Barr Virus2014
- Author(s)
  ６．Seiji Tsunematsu, Mitsuteru Natsuizaka, Hiromi Fujita, Noriyuki Otsuka, Katsumi Terashita, Fumiyuki Sato, Tomoe Kobayashi, Masato Nakai, Yoko Tsukuda, Hiromasa Horimoto, Takuya Sho, Goki Suda, Mitsuru Nakanishi, Satoshi Hashino, Makoto Chuma, Naoya Sakamoto
- Journal Title
  
  Intern Med
  
  Volume: 53(18) Pages: 2079-2082
- NAID
  130004687645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] Once-daily simeprevir in combination with pegylated-interferon and ribavirin: a new horizon in the era of direct-acting antiviral agent therapy for chronic hepatitis C.2014
- Author(s)
  Maekawa S, Enomoto N
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49(1) Issue: 12 Pages: 163-164
- DOI
  10.1371/journal.pone.0082299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590965, KAKENHI-PROJECT-24659204, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25460985, KAKENHI-PROJECT-25293110
[Journal Article] インターフェロン少量長期療法の実際と新薬時代における役割2014
- Author(s)
  須田剛生、坂本直哉
- Journal Title
  
  内科
  
  Volume: 113 Pages: 681-685
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] The J6JFH1 Strain of Hepatitis C Virus Infects Human B-Cells with Low Replication Efficacy.2014
- Author(s)
  Nakai M, Seya T, Matsumoto M, Shimotohno K, Sakamoto N, Aly HH.
- Journal Title
  
  Viral Immunol.
  
  Volume: 27 Issue: 6 Pages: 285-294
- DOI
  10.1089/vim.2013.0140
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22114004, KAKENHI-PROJECT-26670375
[Journal Article] The J6JFH1 strain of hepatitis C virus infects human B cells with low replication efficacy2014
- Author(s)
  Masato Nakai, Tsukasa Seya, Misako Matsumoto, Kunitada Shimotohno, Naoya Sakamoto, and Hussein H Aly
- Journal Title
  
  Viral Immunology
  
  Volume: (in press)
- NAID
  120005468145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] The J6JFH1 strain of hepatitis C virus infects human B cells with low replication efficacy.2014
- Author(s)
  Masato Nakai, Tsukasa Seya, Misako Matsumoto, Kunitada Shimotohno, Naoya Sakamoto, and Hussein H Aly
- Journal Title
  
  Viral Immunology
  
  Volume: in press
- NAID
  120005468145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Telaprevir:副作用とその対策2014
- Author(s)
  須田剛生、坂本直哉
- Journal Title
  
  Internal Medicine
  
  Volume: ６７ Pages: 855-860
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] ITPA genetic variants influence efficacy of PEG-IFN/RBV therapy in older patients infected with HCV genotype 1 and favourable IL28B type.2014
- Author(s)
  Matsuura K, Tanaka Y, Watanabe T, Fujiwara K, Orito E, Kurosaki M, Izumi N, Sakamoto N, Enomoto N, Yatsuhashi H, Kusakabe A, Shinkai N, Nojiri S, Joh T, Mizokami M.
- Journal Title
  
  J Viral Hepat.
  
  Volume: 21 Issue: 7 Pages: 466-474
- DOI
  10.1111/jvh.12171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461004, KAKENHI-PROJECT-26670375
[Journal Article] Heat shock factor 1 accelerates hepatocellular carcinoma development by activating nuclear factor κB/mitogen-activated protein kinase.2014
- Author(s)
  Chuma M, Sakamoto N, Nakai A, Hige S, Nakanishi M, Natsuizaka M, Suda G, Sho T, Hatakaka K, Matsuno Y, Yokoo H, Kamiyama T, Taketomi A, Fujii G, Tashiro K, Hikiba Y, Fujimoto M, Asaka M, Maeda S
- Journal Title
  
  Carcinogenesis
  
  Volume: Epub ahead of print Issue: 2 Pages: 272-281
- DOI
  10.1093/carcin/bgt343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25440010, KAKENHI-PROJECT-25860512, KAKENHI-PROJECT-25860513, KAKENHI-PROJECT-26460982
[Journal Article] Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Haliclona (Reniera) sp.2013
- Author(s)
  Fujimoto Y, Salam KA, Sakamoto N, et al.
- Journal Title
  
  Plos One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185
[Journal Article] IL6を介したC型慢性肝炎のインターフェロン治療抵抗性機構2013
- Author(s)
  須田剛生、坂本直哉
- Journal Title
  
  消化器内科
  
  Volume: 56 Pages: 421-426
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] NX-PVKA assay, a conventional but refined prognostic biomarker for Hepatocellular carcinoma.2013
- Author(s)
  Sakamoto N
- Journal Title
  
  Journal of Gastroenterol and Hepatol
  
  Volume: 28 Issue: 5 Pages: 755-756
- DOI
  10.1111/jgh.12138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Add-on therapy of pitavastatin and eicosapentaenoic acid improves outcome of peginterferon plus ribavirin treatment for chronic hepatitis C.2013
- Author(s)
  Kohjima M, Enjoji M, Sakamoto N, et al.
- Journal Title
  
  J Med Virol
  
  Volume: 85 Issue: 2 Pages: 250-260
- DOI
  10.1002/jmv.23464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] A multi-center survey of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic Hepatitis C in Japan2013
- Author(s)
  Oze T, Hiramatsu N, Mita E, Akuta N, Sakamoto N, et al.
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Issue: 1 Pages: 35-43
- DOI
  10.1111/j.1872-034x.2012.01056.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immunity2013
- Author(s)
  Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-kitazume A, Kiyohashi K, Murakawa M, Nishimura-Sakurai Y, Azuma S, Tasaka-Fujita M, asahina Y, Yoneyama M, Fujita T, Watanabe M
- Journal Title
  
  Hepatology
  
  Volume: 57 Issue: 1 Pages: 46-58
- DOI
  10.1002/hep.26017
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20112009, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-23390108, KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-24890058, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860522
[Journal Article] Wnt5a Signaling Mediates Biliary Differentiation of Fetal Hepatic Stem/Progenitor Cells2013
- Author(s)
  Kakinuma S, Kiyohashi K, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, YoshinoK, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, and *WatanabeM
- Journal Title
  
  Hepatology
  
  Volume: (in press) Issue: 6 Pages: 2502-2513
- DOI
  10.1002/hep.26293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-23790777, KAKENHI-PUBLICLY-24112505, KAKENHI-PUBLICLY-24112519, KAKENHI-PROJECT-24390304, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-25293169, KAKENHI-PROJECT-25293289, KAKENHI-PROJECT-25460271, KAKENHI-PROJECT-25670366, KAKENHI-PROJECT-25860522, KAKENHI-PLANNED-23102003, KAKENHI-PLANNED-23106004
[Journal Article] Hepatitis C virus replication is modulated by the interaction of non-structural protein NS5B and fatty acid synthase.2013
- Author(s)
  Huang JT, Tseng CP, Liao MH, Lu SC, Sakamoto N, et al.
- Journal Title
  
  Journal of Virology
  
  Volume: (Epub) Issue: 9 Pages: 4994-5004
- DOI
  10.1128/jvi.02526-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Hypoxia-inducible Factors Activate CD133 Promoter through ETS Family Transcription Factors2013
- Author(s)
  Ohnishi S, Maehara O, Nakagawa K, Kameya A, Otaki K, Fujita H, Higashi R, Takagi K, Asaka M, Sakamoto N, Kobayashi M, Takeda H
- Journal Title
  
  Plos One
  
  Volume: 8 Issue: 6 Pages: e66255-e66255
- DOI
  10.1371/journal.pone.0066255
- NAID
  120005326763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590074, KAKENHI-PROJECT-24659359
[Journal Article] C型肝炎ウイルス蛋白によるシグナル伝達制御2013
- Author(s)
  須田剛生、坂本直哉
- Journal Title
  
  分子消化器病
  
  Volume: 10 Pages: 68-72
- Data Source
  KAKENHI-PROJECT-25860513
[Journal Article] Cyclophilin A and nuclear factor of activated T cells are essential in cyclosporin A-mediated suppression of polyomavirus BK replication.2013
- Author(s)
  Li YJ, Wu HH, Sakamoto N, et al.
- Journal Title
  
  Am J Transplantation
  
  Volume: 12 Pages: 2348-2362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185
[Journal Article] Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C.2013
- Author(s)
  Nakagawa M, Sakamoto N, Watanabe T, Nishimura-Sakurai Y, Onozuka I, Azuma S, Kakinuma S, Nitta S, Kiyohashi K,Kusano-Kitazume A, Murakawa M, Yoshino K, Itsui Y, Tanaka Y, Mizokami M,Watanabe M, Ochanomizu Liver Conference Study Group
- Journal Title
  
  Hepatol Int
  
  Volume: 7(1) Issue: 1 Pages: 153-161
- DOI
  10.1007/s12072-012-9363-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958
[Journal Article] 肝炎ウイルス学近年の進歩2013
- Author(s)
  坂本直哉
- Journal Title
  
  診断と治療
  
  Volume: 101(9) Pages: 1283-1286
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Model incorporating the ITPA genotype identifies patients at high risk of anemia and treatment failure with pegylated-interferon plus ribavirin therapy for chronic hepatitis C.2013
- Author(s)
  Kurosaki M, Sakamoto N, Asahina Y, Izumi N et al
- Journal Title
  
  J Med Virol
  
  Volume: 85 Issue: 3 Pages: 449-458
- DOI
  10.1002/jmv.23497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-24790728, KAKENHI-PROJECT-24890058, KAKENHI-PROJECT-24590964
[Journal Article] Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis2012
- Author(s)
  Masayuki Kurosaki
- Journal Title
  
  Antiviral Therapy
  
  Volume: 17(1) Issue: 1 Pages: 35-43
- DOI
  10.3851/imp1923
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590982, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-24590964
[Journal Article] Cyclophilin A and nuclear factor of activated T cells are essential in cyclosporin A-mediated suppression of polyomavirus BK replication2012
- Author(s)
  Li YJ, Wu HH, Weng CH, Chen YC, Hung CC, Yang CW, Wang YL, Sakamoto N, Tian YC.
- Journal Title
  
  Am J Transplantation
  
  Volume: 12(9) Issue: 9 Pages: 2348-2362
- DOI
  10.1111/j.1600-6143.2012.04116.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] C型肝炎治療のEBM : テラプレビル2012
- Author(s)
  坂本直哉
- Journal Title
  
  肝胆膵
  
  Volume: 64(3) Pages: 319-325
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] HBV無症候性キャリアの自然経過と診療2012
- Author(s)
  中西満、坂本直哉
- Journal Title
  
  肝胆膵
  
  Volume: 65 (4) Pages: 627-634
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Inhibition of Hepatitis C Virus Replication and Viral Helicase by Ethyl Acetate Extract of the Marine Feather Star Alloeocomatella polycladia2012
- Author(s)
  Yamashita A, Maekawa S, et al
- Journal Title
  
  Mar.Drugs
  
  Volume: 10 Issue: 4 Pages: 744-761
- DOI
  10.3390/md10040744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-22590724, KAKENHI-PROJECT-22603007, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-24659359
[Journal Article] HBV無症候性キャリアの自然経過と診療2012
- Author(s)
  中西満、坂本直哉
- Journal Title
  
  医学のあゆみ
  
  Volume: 242 (5) Pages: 401-406
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Data Mining Analysis of Hepatocellular Carcinoma Risk Predictors in Chronic Hepatitis C2012
- Author(s)
  Kurosaki M, Hiramatsu N, Sakamoto M, Suzuki Y, iwasaki M, Tamori A, Matsuura K, Kakinuma S, Sugauchi F, Sakamoto N, Nakagawa M, Izumi NHiramatsu N, Sakamoto M, Suzuki Y, iwasaki M, Tamori A, Matsuura K, Kakinuma S, Sugauchi F, Sakamoto N
- Journal Title
  
  C.J Hepatol
  
  Volume: 56(3) Pages: 602-8
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis2012
- Author(s)
  Kurosaki M, Kakinuma S, Sakamoto N, Nakagawa M, et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 17(1) Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Let-7b is a novel regulator of hepatitis C virus replication. Cell Mol Life Sci 20122012
- Author(s)
  Cheng J-C, Yeh YJ, Tseng CP, Hsu SD, Chang YL, Sakamoto N, Huang HD
- Journal Title
  
  EPub ahead of Print
  
  Volume: 69 Issue: 15 Pages: 2621-2633
- DOI
  10.1007/s00018-012-0940-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] C型肝炎の近未来治療2012
- Author(s)
  坂本直哉
- Journal Title
  
  化学療法の領域
  
  Volume: 28(S-1) Pages: 1134-1140
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives2012
- Author(s)
  Nichols DB, Fournet G, Gurukumar KR, Basu A, Lee JC, Sakamoto N, Kozielski F, Musmuca I, Joseph B, Ragno R, Kaushik-Basu N
- Journal Title
  
  Eur J MedChem
  
  Volume: 49 Pages: 191-199
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives2012
- Author(s)
  Kaushik-Basu N, Sakamoto N
- Journal Title
  
  Eur J Med Chem
  
  Volume: 49 Pages: 191-199
- DOI
  10.1016/j.ejmech.2012.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine sponge Amphimedon sp.2012
- Author(s)
  Fujimoto Y
- Journal Title
  
  PLoS One.
  
  Volume: 7 Issue: 11 Pages: 744-761
- DOI
  10.1371/journal.pone.0048685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590724, KAKENHI-PROJECT-22603007, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-23590544, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659204, KAKENHI-PROJECT-24659359
[Journal Article] Suppression of hepatitis C virus replicon by adenovirus vector-mediated expression of tough decoy RNA against miR-122a. Virus Research2012
- Author(s)
  Sakurai F, Furukawa N, Higuchi M, Okamoto S, Ono K, Yoshida T, Kondoh M, Yagi K, Sakamoto N, Katayama K, Mizuguchi H
- Journal Title
  
  EPub ahead of Print
  
  Volume: 165 Issue: 2 Pages: 214-218
- DOI
  10.1016/j.virusres.2012.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis2012
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Journal Title
  
  Antivir Ther
  
  Volume: 17(1) Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] C型肝炎治療薬テラプレビル2012
- Author(s)
  坂本直哉
- Journal Title
  
  薬局
  
  Volume: 63 (1) Pages: 123-128
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyonashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 56(3) Pages: 1315-1323
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] 座談会-B型肝炎 : 克服へのロードマップ2012
- Author(s)
  坂本直哉
- Journal Title
  
  肝胆膵
  
  Volume: 65(4) Pages: 763-778
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyonashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 56(3) Pages: 1315-23
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Anemia and thrombocytosis induced by ribavirin monotherapy in patients with chronic hepatitis C.2012
- Author(s)
  Kobayashi T, Hige s, Sakamoto N, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Issue: 11 Pages: 1228-1237
- DOI
  10.1007/s00535-012-0579-y
- NAID
  10031126955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis2012
- Author(s)
  Kurosaki M, Hiramatsu N, Sakamoto M, Suzuki Y, Iwasaki M, Tamori A, Matsuura K, Kakinuma S, Sakaguchi F, Sakamoto N, Nakagawa M, Izumi N
- Journal Title
  
  C.J Hepatol
  
  Volume: 56(3) Pages: 602-8
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis2012
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 17(1) Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyonashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 56(3) Issue: 3 Pages: 1315-23
- DOI
  10.1128/aac.05764-11
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-23790778, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590959, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-21249013
[Journal Article] Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C2012
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, et al.
- Journal Title
  
  J Hepatol
  
  Volume: 56(3) Issue: 3 Pages: 602-608
- DOI
  10.1016/j.jhep.2011.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590836, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790632, KAKENHI-PROJECT-23590982, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590957, KAKENHI-PROJECT-24590958, KAKENHI-PROJECT-24659359
[Journal Article] Ochanomizu Liver Conference Study Group : Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C.2012
- Author(s)
  Nakagawa M, Sakamoto N, Watanabe T, et al.
- Journal Title
  
  Hepatol Int
  
  Volume: (Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390185
[Journal Article] Age and total ribavirin dose are independent predictors of relapse after interferon therapy in chronic hepatitis C revealed by data mining analysis2012
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Journal Title
  
  Antivir Ther
  
  Volume: 17(1) Pages: 35-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831
[Journal Article] Ochanomizu Liver Conference Study Group : Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C2012
- Author(s)
  Nakagawa M, Sakamoto N, Watanabe T, Nishimura-Sakurai Y, Onozuka I, Azuma S, Kakinuma S, Nitta S, Kiyohashi K, Kusano-Kitazume A, Murakawa M, Yoshino K, Itsui Y, Tanaka Y, Mizokami M, Watanabe M
- Journal Title
  
  Hepatol Int
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Factors responsible for the discrepancy between IL28B polymorphism prediction and the viral response to peginterferon plus ribavirin therapy in Japanese chronic hepatitis C patients2012
- Author(s)
  Saito H, Ito K, Sugiyama M, Matsui T, Aoki Y, Imamura M, Murata K, Masaki N, Nomura H, Adachi H, Hige S, Enomoto N, Sakamoto N, Kurosaki M, Mizokami M, Watanabe S
- Journal Title
  
  Hepatol Res
  
  Volume: 42(10) Issue: 10 Pages: 958-65
- DOI
  10.1111/j.1872-034x.2012.01013.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23591005, KAKENHI-PROJECT-23890255, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24659359
[Journal Article] Identification of novel N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N(equalcontribution), Okuno Y, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyonashi K, Nitta S, Murakawa M, Azuma S, Nishimura-Sakurai Y, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 56(3) Pages: 1315-1323
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Ochanomizu Liver Conference Study Group : Association of ITPA gene variant and serum ribavirin concentration with blood cells decline in pegylated interferon-alfa plus ribavirin therapy for chronic hepatitis C2012
- Author(s)
  Nakagawa M, Sakamoto N, Watanabe T, Nishimura-Sakurai Y, Onozuka I, Azuma S, Kakinuma S, Nitta S, Kiyohashi K, Kusano-Kitazume A, Murakawa M, Yoshino K, Itsui Y, Tanaka Y, Mizokami M, Watanabe M.
- Journal Title
  
  Hepatol Int
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis Cvirus cell culture.2011
- Author(s)
  Machi Yamamoto, Naoya Sakamoto, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Serum interleukin-6 levels can predict resistance to treatment of chronic hepatitis C infection with pegylated-interferon alpha 2b plus ribavirin.2011
- Author(s)
  Mayumi Ueyama, Mina Nakagawa, Naova Sakamoto, Seishin Azuma, Mamoru Watanabe, et al.
- Journal Title
  
  Antivral Therapy
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes..2011
- Author(s)
  Toyoda M, Kitaoka A, Machida K, Nishinakagawa T, Yada R, Kohjima M, Kato M, Kotoh K, Sakamoto N, et al.
- Journal Title
  
  Int J Mol Med
  
  Volume: (EPub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection2011
- Author(s)
  Yoshida T, Takayama K, Kondoh M, Sakurai F, Tani H, Sakamoto N, Matsuura Y, Mizuguchi H, Yagi K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 416(1-2) Pages: 119-124
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture2011
- Author(s)
  Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Kato T, Wakita T, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Issue: 3 Pages: 258-269
- DOI
  10.1111/j.1872-034x.2010.00771.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23790778
[Journal Article] Serum interleukin-6 levels can predict resistance to treatment of chronic hepatitis C infection with pegylated-interferon alpha 2b plus ribavirin2011
- Author(s)
  Ueyama M, Nakagawa M, Sakamoto N, Onozuka I, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Kitazume A, Murakawa M, Nishimura-Sakurai Y, Sekine-Osajima Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 1081-1091
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Analysis of the complete open reading frame of hepatitis C virus in genotype 2a infection reveals critical sites influencing the response to peginterferon and ribavirin therapy2011
- Author(s)
  Kadokura M, Nakagawa M, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  Hepatol Int
  
  Volume: 5(3) Issue: 3 Pages: 789-799
- DOI
  10.1007/s12072-011-9267-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-24659359
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture2011
- Author(s)
  Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Tsuchiya K, Kato T, Wakita T, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 258-269
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes2011
- Author(s)
  Toyoda M, Kitaoka A, Machida K, Nishinakagawa T, Yada R, Kohjima M, Kato M, Kotoh K, Sakamoto N, Shiota G, Nakamuta M, Nakashima M, Enjoji M
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Pages: 619-624
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K,Watanabe M
- Journal Title
  
  J Virol
  
  Volume: 85 Issue: 12 Pages: 5986-94
- DOI
  10.1128/jvi.02583-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22790633, KAKENHI-PUBLICLY-23130506
[Journal Article] Inhibitory effect of a triterpenoid compound, with or without alpha interferon, on hepatitis C virus infection2011
- Author(s)
  Watanabe T, Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 55(6) Issue: 6 Pages: 2537-2545
- DOI
  10.1128/aac.01780-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790778
[Journal Article] Pre-treatment prediction of response to pegylated-interferon plus ribavirin for chronic hepatitis C using genetic polymorphism in IL28B and viral factors2011
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Journal Title
  
  J Hepatol
  
  Volume: 54 Issue: 3 Pages: 439-448
- DOI
  10.1016/j.jhep.2010.07.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590836, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117
[Journal Article] Analysis of the complete open reading frame of genotype 2b hepatitis C virus in association with the response to peginterferon and ribavirin therapy2011
- Author(s)
  Kadokura M, Maekawa S, Sueki R, Miura M, Komase K, Shindo H, Amemiya F, Uetake T, Inoue T, Sakamoto M, Nakagawa M, Sakamoto N, Watanabe M, Enomoto N
- Journal Title
  
  PLoS One
  
  Volume: 6(9)
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Adenovirus vector-mediated assay system for Hepatitis C virus replication.2011
- Author(s)
  Takeshi Yoshida, Masuo Kondoh, Manabu Ojima, Hiroyuki Mizuguchi, Naoya Sakamoto
- Journal Title
  
  Nucl Acid Res
  
  Volume: (EPub ahead ofprint)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Tanaka Y, Sakamoto N, et al.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 20(17) Issue: 17 Pages: 3507-3516
- DOI
  10.1093/hmg/ddr249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21390227, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21659186, KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-23390201
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-alpha2b plus ribavirin2011
- Author(s)
  Ueyama M, Nakagawa M, Sakamoto N, et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 1081-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Sequences in the interferon sensitivity-determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG-interferon plus ribavirin : data mining analysis2011
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, et al.
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 3 Pages: 445-452
- DOI
  10.1002/jmv.22005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790633
[Journal Article] Suppression of Hath1 gene expression directly regulated by Heslvia Notch signaling is associated with goblet cell depletion in ulcerative colitis2011
- Author(s)
  Zheng X, Nakamura T, et al
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17 Issue: 11 Pages: 2251-2260
- DOI
  10.1002/ibd.21611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590805, KAKENHI-PUBLICLY-22117508, KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-22590694, KAKENHI-PROJECT-22590695, KAKENHI-PUBLICLY-23130506, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24659359
[Journal Article] Inhibitory effect of triterpenoid compound, with or without interferon-alpha, on hepatitis C virus infection2011
- Author(s)
  Watanabe T, Sakamoto N, Nakagawa M, Kakinuma S, Itsui Y, Nishimura-Sakurai Y, Ueyama M, Funaoka Y, Kitazume A, Nitta S, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Oooka S, Watanabe M
- Journal Title
  
  Antimicrob Agent Chemother
  
  Volume: 55 Pages: 2537-45
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice2011
- Author(s)
  Onozuka I, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Issue: 1 Pages: 134-140
- DOI
  10.1016/j.bbrc.2011.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22591762, KAKENHI-PROJECT-22659145, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23689040
[Journal Article] Studies on virus kinetics using injbctious fluorescence-tagged hepatitis C ViruS Cell Culture.2011
- Author(s)
  Machi Yamamoto, Naoya Sakamoto, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Adenovirus vector-mediated assay system for hepatitis C virus replication2011
- Author(s)
  Yoshida T, Kondoh M, Ojima M, Mizuguchi H, Yamagishi Y, Sakamoto N, Yagi K.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39(10)
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Analysis of the complete open reading frame of genotype 2b hepatitis C virus inassociation with the response to peginterferon and ribavirin therapy2011
- Author(s)
  Kadokura M, Maekawa S, Sueki R, Miura M, Komase K, Shindo H, Amemiya F, Uetake T, Inoue T, Sakamoto M, Nakagawa M, Sakamoto N, Watanabe M, Enomoto N
- Journal Title
  
  PLoSOne
  
  Volume: 6(9)
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association of IL28B polymorphism withresponse to pegylated-interferon alpha plusribavirin combination therapy in patientswith chronic genotype 2 hepatitis C2011
- Author(s)
  Sakamoto N, Nakagawa M, Tanaka Y, Sekine-Osajima Y, Ueyama M, Kurosaki M, Nishida N, Tamori A, Nishimura-Sakurai Y, Itsui Y, Azuma S, Kakinuma S, Hige S, Ito Y, Tanaka E, Hiasa Y, Izumi N, Tokunaga K, Mizokami M, Watanabe M
- Journal Title
  
  JMedical Virol
  
  Volume: 83 Pages: 871-878
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Pretreatment prediction of anemia progression by pegylated interferon a2b plus ribavirin combination therapy in chronic hepatitis C infection : Decision-tree analysis2011
- Author(s)
  Hiramatsu N, Kurosaki M, Sakamoto N, Iwasaki M, Sakamoto M, Suzuki Y, Sakaguchi F, Tamori A, Kakinuma S, Matsuura K, Izumi N
- Journal Title
  
  JGastroenterol
  
  Volume: 46 Pages: 1111-19
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Association of IL28B variants with response to pegylated-interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b2011
- Author(s)
  Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Journal Title
  
  J Med Virol
  
  Volume: 83 Issue: 5 Pages: 871-878
- DOI
  10.1002/jmv.22038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590833, KAKENHI-PROJECT-22390151, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22710191, KAKENHI-PROJECT-22790633, KAKENHI-PROJECT-23390117, KAKENHI-PROJECT-23790778
[Journal Article] Pretreatment Prediction of response to peginterferon plus ribavirin inchronic hepatitis C using data mining analysis.2011
- Author(s)
  Masayuki Kurosaki, Naoya Sakamoto, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection withpegylated-interferon-α2b plus ribavirin2011
- Author(s)
  Ueyama M, Nakagawa M, Sakamoto N,Onozuka I, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Kitazume A, Murakawa M, Nishimura-Sakurai Y, Sekine-Osajima Y, Itsui Y, Azuma S, Kakinuma S, Watanabe M and the Ochanomizu-Liver Conference Study Group
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Issue: 7 Pages: 1081-1091
- DOI
  10.3851/imp1864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-23790778
[Journal Article] Adenovirus vector-mediated assay system for hepatitis C virus replication2011
- Author(s)
  Yoshida T, Kondoh M, Ojima M, Mizuguchi H, Yamagishi Y, Sakamoto N, Yagi K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39(10)
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association of gene expression involving innate immunity and genetic variation in IL28B with antiviral response2011
- Author(s)
  Asahina Y, Sakamoto N, et al
- Journal Title
  
  Hepatology
  
  Volume: 55(1) Issue: 1 Pages: 20-29
- DOI
  10.1002/hep.24623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21659186, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-24390185, KAKENHI-PROJECT-24590960, KAKENHI-PROJECT-24659359, KAKENHI-PROJECT-24890058
[Journal Article] A new method for induced fit docking(GENIUS) and its application to virtual screening of novel HCV NS3-4A protease inhibitors2011
- Author(s)
  Takaya D, Yamashita A, Kamijo K, Gomi J, Ito M, Maekawa S, Enomoto N, SakamotoN, Watanabe Y, Arai R, Umeyama H, Honma T, Matsumoto T, Yokoyama S
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 19(22) Pages: 6892-6905
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylatedinterferon and ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Tanaka Y, Kurosaki M, Nishida N, Sugiyama M, Matsuura K, Sakamoto N, Enomoto N, Yatsuhashi H, Nishiguchi S, Hino K, Hige S, Itoh Y, Tanaka E, Mochida S, Honda M, Hiasa Y, Koike A, Sugauchi F, Kaneko S, Izumi N, Tokunaga K, Mizokami M
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 20(17) Pages: 3507-3516
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-alpha2b plus ribavirin2011
- Author(s)
  Ueyama M, Sakamoto N, et al
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 1081-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis2011
- Author(s)
  Kurosaki M, Sakamoto N, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(3) Issue: 3 Pages: 401-409
- DOI
  10.1007/s00535-010-0322-5
- NAID
  10029028096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145
[Journal Article] Association of IL28B polymorphism with response to pegylated-interferon alpha plus ribavirin combination therapy in patients with chronic genotype 2 hepatitis C.2011
- Author(s)
  Naova Sakamoto, et al.
- Journal Title
  
  JMedical Virol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] A new method for induced fit docking (GENIUS) and its application to virtual screening of novel HCV NS3-4A protease inhibitors2011
- Author(s)
  Takaya D, Sakamoto N, et al.
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 19(22) Issue: 22 Pages: 6892-6905
- DOI
  10.1016/j.bmc.2011.09.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-21659186, KAKENHI-PROJECT-22590724, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-23390195, KAKENHI-PROJECT-24659359
[Journal Article] Analysis of the complete open reading frame of genotype 2b hepatitis C virus in association with the response to peginterferon and ribavirin therapy2011
- Author(s)
  Kadokura M, Nakagawa M, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  PLoS One
  
  Volume: 6(9) Issue: 9 Pages: e24514-e24514
- DOI
  10.1371/journal.pone.0024514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590837, KAKENHI-PROJECT-21659186, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-23390195
[Journal Article] Pretreatment Prediction of Anemia Progression by Peginterferon Plus Ribavirin Therapy in Chronic Hepatitis C : Decision-Tree Analysis2011
- Author(s)
  Hiramatsu N, Sakamoto N, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(9) Issue: 9 Pages: 1111-1119
- DOI
  10.1007/s00535-011-0412-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-21590836, KAKENHI-PROJECT-22659145, KAKENHI-PROJECT-22790632
[Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Funaoka Y, Sakamoto N(equal contribution), Nakagawa M, Kakinuma S, Suda S, Watanabe T, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, and Watanabe M
- Journal Title
  
  J Virol
  
  Volume: 85(12) Pages: 5986-5994
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Adenovirus vector-mediated assay system for hepatitis C virus replication2011
- Author(s)
  Yoshida T, Sakamoto N, et al
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39(10) Issue: 10 Pages: e64-e64
- DOI
  10.1093/nar/gkr047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22659145
[Journal Article] Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection2011
- Author(s)
  Yoshida T, Sakamoto N, et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 416(1-2) Issue: 1-2 Pages: 119-124
- DOI
  10.1016/j.bbrc.2011.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-24659359
[Journal Article] Serum interleukin-6 levels can predict resistance to treatment of chronichepatitis C infection with pegylated-interferon alpha 2b plus ribavirin.2011
- Author(s)
  Mayumi Ueyama, Mina Nakagawa, Naova Sakamoto, Seishin Azuma, Mamoru Watanabe, et al.
- Journal Title
  
  Antiviral Therapy
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection2011
- Author(s)
  Yoshida T, Takayama K, Kondoh M, Sakurai F, Tani H, Sakamoto N, Matsuura Y, Mizuguchi H, Yagi K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 416(1-2) Pages: 119-124
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Funaoka Y, Sakamoto N, Suda G, Itsui Y, Nakagawa M, Kakinuma S, Watanabe T, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Watanabe M
- Journal Title
  
  J Virol
  
  Volume: 85 Pages: 5986-94
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Association between hpid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes.2011
- Author(s)
  Tbyoda M, Kitaoka A, Machida K, Nishinakagawa T, Yada R, Kohjima M, Kato M, Kotoh K, Sakamoto N, et al.
- Journal Title
  
  Int J Mol Med
  
  Volume: (EPub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Pretreatment Prediction of response to peginterferon plus ribavirin in chronic hepatitis C using data mining analysis.2011
- Author(s)
  Masayuki Kurosaki, Naoya Sakamoto, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Sequences in the Interferon Sensitivity Determining Region and Core Region of Hepatitis C Virus Impact Pretreatment Prediction of Response to Peg-interferon Plus Ribavirin : Data Mining Analysis.2011
- Author(s)
  Masayuki Kurosaki, Naoya Sakamoto, Manabu Iwasaki, Minoru Sakamoto, et al.
- Journal Title
  
  J Medical Virol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes2011
- Author(s)
  Toyoda M, Kitaoka A, Machida K, Nishinakagawa T, Yada R, Kohjima M, Kato M, Kotoh K, Sakamoto N, Shiota G, Nakamuta M, Nakashima M, Enjoji M
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Pages: 619-624
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-alpha2b plus ribavirin2011
- Author(s)
  Ueyama M, Nakagawa M, Sakamoto N, et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 1081-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Funaoka Y, Sakamoto N, Kakinuma S, Azuma S, Watanabe M, et al
- Journal Title
  
  Journal of Virology
  
  Volume: 85 Pages: 5986-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Pre-treatment prediction of response topegylated-interferon plus ribavirin forchronic hepatitis C using genetic polymorphism in IL28B and viral factors2011
- Author(s)
  Kurosaki M, Tanaka Y, Nishida N, Sakamoto N, Enomoto N, Honda M, SugiyamaM, Matsuura K, Sugauchi F, Asahina Y, Nakagawa M, Watanabe M, Sakamoto M, Maekawa S, Sakai A, Kaneko S, Ito K, Masaki N, Tokunaga K, Izumi N, Mizokami M
- Journal Title
  
  JHepatol
  
  Volume: 54 Pages: 439-448
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Serum interleukin-6 levels correlate with resistance to treatment of chronic hepatitis C infection with pegylated-interferon-alpha2b plus ribavirin2011
- Author(s)
  Ueyama M, Sakamoto N, et al
- Journal Title
  
  Antivir Ther
  
  Volume: 16 Pages: 1081-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831
[Journal Article] NCV-NS4B蛋白とIFN発現計シグナル分子との分子間相互作用の解析2011
- Author(s)
  新田沙由梨,坂本直哉
- Journal Title
  
  消化器と免疫
  
  Volume: 48 Pages: 174-177
- Data Source
  KAKENHI-PROJECT-24659359
[Journal Article] Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes2011
- Author(s)
  Toyoda M, Sakamoto N, et al
- Journal Title
  
  Int J Mol Med
  
  Volume: 27 Issue: 5 Pages: 619-624
- DOI
  10.3892/ijmm.2011.622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832
[Journal Article] The inhibitory effect on hepatitis C virus infection of a triterpenoid compound, with or without interferon-alpha2011
- Author(s)
  Watanabe T, Sakamoto N, Nakagawa M, Kakinuma S, Itsui Y, Nishimura-Sakurai Y, Ueyama M, Funaoka Y, Kitazume A, Nitta S, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Oooka S, Watanabe M
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 55(6) Pages: 2537-2545
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice2011
- Author(s)
  Kakinuma S, Onozuka I, Kamiya A, Miyoshi M, Sakamoto N, Kiyohashi K, Watanabe T, Funaoka Y, Ueyama M, NakagawaM, Koshikawa N, Seiki M, Nakauchi H, and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 134-140
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture2011
- Author(s)
  Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Tsuchiya K, Kato T, Wakita T, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 41 Pages: 258-269
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Association of gene expression involving innate immunity and genetic variation in IL28B with antiviral response2011
- Author(s)
  Asahina Y, Sakamoto N, et al.
- Journal Title
  
  Hepatology
  
  Volume: 55(1) Pages: 20-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Adenovirus vector-mediated assay system for hepatitis C virus replication2011
- Author(s)
  Yoshida T, Sakamoto N, et al.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39(10)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Association of IL28B polymorphism with response to pegylated-interferonalpha plus ribavirin combination therapy in patients with chronic genotype 2 hepatitis C.2011
- Author(s)
  Naoya Sakamoto, et al.
- Journal Title
  
  J Medical Virol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Association of gene expression involving innate immunity and genetic variation in IL28B with antiviral response2011
- Author(s)
  Asahina Y, Tsuchiya K, Muraoka M, TanakaK, Suzuki Y, Tamaki N, Hoshioka Y, Yasui Y, Katoh T, Hosokawa T, Ueda K, Nakanishi H, Itakura J, Takahashi Y, Kurosaki M, Enomoto N, Nitta S, Sakamoto N, Izumi N
- Journal Title
  
  Hepatology
  
  Volume: 55(1) Pages: 20-29
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] The inhibitory effect on hepatitis C virus infection of a triterpenoid compound, with or without interferon-alpha2011
- Author(s)
  Watanabe T, Sakamoto N, Nakagawa M, Kakinuma S, Itsui Y, Nishimura-Sakurai Y, Ueyama M, Funaoka Y, Kitazume A, Nitta S, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, Oooka S, Watanabe M
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 55(6) Pages: 2537-2545
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Funaoka Y, Sakamoto N, Nakagawa M, Kakinuma S, Suda S, Watanabe T, Nitta S, Kitazume A, Kiyohashi K, Murakawa M, Azuma S, Tsuchiya K, and Watanabe M
- Journal Title
  
  J Virol
  
  Volume: 85(12) Pages: 5986-5994
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] シクロフィリン阻害剤2011
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Journal Title
  
  肝胆膵
  
  Volume: 62 Pages: 403-412
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Sequences in the Interferon Sensitivity Determining Region and Core Region of Hepatitis C Virus Impact Pretreatment Prediction of Response toPeg-interferon Plus Ribavirin : Data Mining Analysis.2011
- Author(s)
  Masayuki Kurosaki, Naoya Sakamoto, Manabu Iwasaki, Minoru Sakamoto, et al.
- Journal Title
  
  J Medical Virol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway.2010
- Author(s)
  KyeongJin Kim, Kook Hwan Kim, Hye Young Kim, Hyun Kook Cho, Naova Sakamoto., et al.
- Journal Title
  
  FEBS Letter
  
  Volume: 584 Pages: 707-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants2010
- Author(s)
  Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.2010
- Author(s)
  Tomokazu Mizui, Shunhei Yamashina, Isei Tanida, Motoki Takashima, Naova Sakamoto, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 5 Pages: 195-203
- NAID
  10027214573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2010
- Author(s)
  Suda G, Sakamoto N, Itsui Y, Nakagawa M, Mishima K, Onuki-Karakama Y, Yamamoto M, Funaoka Y, Watanabe T, Kiyohashi K, Nitta S, Azuma S, Kakinuma S, Tuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N,Mogushi K, Nagaie S, Nakagawa M,Itsui Y, Sekine-Osajima Y,Tasaka-Fujita M, Onuki-Karakama Y,Suda G, Mishima M, Yamamoto M,Ueyama M, Funaoka Y, Watanabe T,Chen CH, Kakinuma S, Tsuchiya K,Tanaka H, Enomoto N, Watanabe M
- Journal Title
  
  J Gastroentorol (in press)
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790485
[Journal Article] Cen culture and in-vivo analyses of plaque-derived cytopathic hepatitis C Vlrus mutants.2010
- Author(s)
  Kako Mishima, Naova Sakamoto, et al
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2010
- Author(s)
  Suda G, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Azuma S, Kakinuma S, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway2010
- Author(s)
  Kim K, Kim KH, Kim HY, Cho HK, Sakamoto N, Cheong J
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 707-712
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] ITPA gene variant protects against anemia induced by pegylated interferon-alfa and ribavirin therapy for Japanese patients with chronichepatitis C2010
- Author(s)
  Naova Sakamoto, Yasuhito Tanaka, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 40 Pages: 1063-1071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Comparison of HCVLassociated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010
- Author(s)
  Yuki Nishimura-Sakurai, Naoya Sakamoto, et al.
- Journal Title
  
  JGastroentorol
  
  Volume: 45 Pages: 523-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Cell culture and in-vivo analyses of plaque-derived cytopathic hepatitis Cvirus mutants.2010
- Author(s)
  Suda G, Sakamoto N, Azuma S
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection.2010
- Author(s)
  Nakagawa M, Sakamoto N, Ueyama M, Mogushi K, Nagaie S, Itsui Y, Azuma S, Kakinuma S, Tanaka H, Enomoto N, Watanabe M
- Journal Title
  
  J Gastroentorol (in press)
- NAID
  10027216778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790485
[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirin for Chronic Hepatitis C using Genetic Polymorphism in IL28B and Viral Factors.2010
- Author(s)
  Masayuki Kurosaki, Yasuhito Tanaka, Nao Nishida, Masaya Sugiyama, Naoya Sakamoto, et al.
- Journal Title
  
  J Hepatol
  
  Volume: (EPub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-richprotein kinase.2010
- Author(s)
  Yuko Karakama, Naoya Sakamoto, et al.
- Journal Title
  
  Antimicrobial Agent and Chemotherapy
  
  Volume: 54 Pages: 3179-3186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway.2010
- Author(s)
  Kim K, Sakamoto N, et al
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 707-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus'associated autophagy.2010
- Author(s)
  Tomokazu Mizui, Shunhei Yamashina, Isei Tanida, MotokiTakashima, Naova Sakamoto, etal.
- Journal Title
  
  J Gastroenterol
  
  Volume: 5 Pages: 195-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] HCVの複製・増殖機構と遺伝子型・遺伝子変異2010
- Author(s)
  筬島裕子、中川美奈、坂本直哉
- Journal Title
  
  日本臨床
  
  Volume: 69 Pages: 52-58
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Mutations in the Interferon Sensitivity Determining Region and virological response to combination therapy with Pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection.2010
- Author(s)
  Nakagawa M, Sakamoto N(equal contribution), et al
- Journal Title
  
  J Gastroenterol (in press)
- NAID
  10027216778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] ITPA gene variant protects against anemia induced by pegylated interferon-alfa and ribavirin therapy for Japanese patients with chronic hepatitis C2010
- Author(s)
  Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 1063-1071
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] SR蛋白リン酸化酵素阻害剤によるHCV増殖抑制効果の解析2010
- Author(s)
  唐鎌優子、坂本直哉、井津井康浩、中川美奈、藤田めぐみ、櫻井幸、柿沼晴、大岡真也、東正新、土屋輝一郎、小野木博、萩原正敏、渡辺守
- Journal Title
  
  消化器内科
  
  Volume: 51(6) Pages: 632-635
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] ITPA gene variant protects against anemia induced by pegylated in terferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C.2010
- Author(s)
  Sakamoto N, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 40 Pages: 1063-1071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590720
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010
- Author(s)
  Nishimura-Sakurai Y, Sakamoto, N, Sekine-Osaiima Y, et al.
- Journal Title
  
  J.Gastroenterol
  
  Volume: 45 Pages: 523-536
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590720
[Journal Article] Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1pathway2010
- Author(s)
  KyeongJin Kim, Kook Hwan Kim, Hye Ybung Kim, Hyun Kook Cho, Naova Sakamoto, et al.
- Journal Title
  
  FEBS Letter
  
  Volume: 584 Pages: 707-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2010
- Author(s)
  Suda G, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Azuma S, Kakinuma S, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Mutations in the interferon sensitivity determining region and virological response to combination therapy with pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection2010
- Author(s)
  Nakagawa M, Sakamoto N, Ueyama M, Mogushi K, Nagaie S, Itsui Y, Azuma S, Kakinuma S, Tanaka H, Enomoto N, Watanabe M
- Journal Title
  
  J Gastroentorol
  
  Volume: 45 Pages: 656-665
- NAID
  10027216778
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-rich protein kinase2010
- Author(s)
  Karakama Y, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Nishimura-Sakurai Y, Kakinuma S, Oooka S, Azuma S, Tsuchiya K, Onogi H, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob AgentChemother
  
  Volume: 54 Pages: 3179-86
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Inhibition of hepatitis C virus replication by a specific inhibitor of serine-arginine-rich protein kinase2010
- Author(s)
  Karakama Y, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Nishimura-Sakurai Y, Kakinuma S, Oooka M, Azuma S, Tsuchiya K, Onogi H, Hagiwara M, Watanabe M
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 54 Pages: 3179-3186
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells2010
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N, Kakinuma S, Azuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Gastroenterorlogy (印刷中(Epub ahead of print))
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.2010
- Author(s)
  Suda G, Sakamoto N, Azuma S, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-rich protein kinase.2010
- Author(s)
  Yuko Karakama,Naoya Sakamoto, et al.
- Journal Title
  
  Antimicrobial Agent and Chemotherapy
  
  Volume: 54 Pages: 3179-3186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Cell culture and in-vivo analyses of plaque-derived cytopathic hepatitis C virus mutants2010
- Author(s)
  Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Tuchiya K, Imamura M, Chayama K, Wakita T, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones.2010
- Author(s)
  Goki Suda, Naova Sakamoto, et al.
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] ITPA gene variant protects against anemia induced by pegylated interferon-alpha and ribavirin therapy for Japanese patients with chronic hepatitis C2010
- Author(s)
  Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Honda M, Ito K, Mizokami M, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 40 Pages: 1063-1071
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] IL-6-mediated intersubgenotypic variation of interferon sensitivity inhepatitis C virus genotype 2a/2b chimeric clones.2010
- Author(s)
  Goki Suda, Naova Sakamoto, et al.
- Journal Title
  
  Virology
  
  Volume: 407 Pages: 80-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-rich protein kinase2010
- Author(s)
  Karakama Y, Sakamoto N, Kakinuma S, Azuma S, Watanabe M, et al.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 54 Pages: 3179-3186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Pretreatment Prediction of Response to Pegylated-Interferon Plus Ribavirinfor Chronic Hepatitis C using Genetic Polymorphism in IL28B and ViralFactors.2010
- Author(s)
  Masayuki Kurosaki, Yasuhito Tanaka, Nao Nishida, Masaya Sugiyama, Naoya Sakamoto, et al.
- Journal Title
  
  J Hepatol
  
  Volume: (EPub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2010
- Author(s)
  Yuki Nishimura-Sakurai, Naoya Sakamoto, et al.
- Journal Title
  
  J Gastroentorol
  
  Volume: 45 Pages: 523-536
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] ITPA gene variant protects against anemia induced by pegylated interferon-alfa and ribavirin therapy for Japanese patients with chronichepatitis C.2010
- Author(s)
  Naova Sakamoto, Yasuhito Tanaka, et al.
- Journal Title
  
  Hepatology Research
  
  Volume: 40 Pages: 1063-1071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Cell Culture and in vivo analyses of cytopathic hepatitis C virus mutanis2010
- Author(s)
  Mishima K, Sakamoto N, Sekine
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590720
[Journal Article] Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants2010
- Author(s)
  Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Mutations in the Interferon Sensitivity Determining Region and virological response to combination therapy with Pegylated-interferon alpha 2b plus ribavirin in patients with chronic hepatitis C-1b infection.2010
- Author(s)
  Nakagawa M, Sakamoto N(equal contribution), et al.
- Journal Title
  
  J Gastroenterol (in press)
- NAID
  10027216778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells2010
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N, Mogushi K, Nagaie S, Nakagawa M, Itsui Y, Sekine-Osajima Y, Tasaka-Fujita M, Onuki-Karakama Y, Suda G, Mishima M, Yamamoto M, Ueyama M, Funaoka Y, Watanabe T, Chen CH, Kakinuma S, Tsuchiya K, Tanaka H, Enomoto N, Watanabe
- Journal Title
  
  J Gastroentorol
  
  Volume: 45 Pages: 523-36
- NAID
  10027216127
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Cell culture and in vivo analyses of cytopathic hepatitis C virus mutants2010
- Author(s)
  Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Azuma S, Kakinuma S, Kiyohashi K, Kitazume A, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Wakita T, Watanabe M
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Inhibition of HCV replication by a specific inhibitor of serin-arginine-rich protein kinase.2010
- Author(s)
  Yuko Karakama, Naoya Sakamoto, Shinva Oooka, et al.
- Journal Title
  
  Antimicrobial Agent and Chemotherapy
  
  Volume: 54 Pages: 3179-31869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Mutations in the Interferon Sensitivity Determining Region and virological response to combination therapy with Pegylated-interferon alpha 2b plusribavirin in patients with chronic hepatitis C-1b infection.2010
- Author(s)
  Mina Nakagawa, Naoya Sakamoto, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 45 Pages: 656-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article] Mutations in the Interferon Sensitivity Determining Region and virological response to combination therapy with Pegylated-interferon alpha 2b plusribavirin in patients with chronic hepatitis C-1b infection.2010
- Author(s)
  Mina Nakagawa, Naoya Sakamoto, et al.
- Journal Title
  
  JGastroenterol
  
  Volume: 45 Pages: 656-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Cell culture and in-vivo analyses of plaque-derived cytopathic hepatitis Cvirus mutants.2010
- Author(s)
  Kako Mishima, Naoya Sakamoto, et al
- Journal Title
  
  Virology
  
  Volume: 405 Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659145
[Journal Article]2009
- Author(s)
  坂本直哉、横田隆徳
- Journal Title
  
  siRNAによるC型肝炎遺伝子治療.バイオ医薬品の開発技術とシーズ(シーエムシー出版)
  
  Pages: 246-251
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein.2009
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Azuma S, Watanabe M, et al.
- Journal Title
  
  Hepatology 50
  
  Pages: 1727-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Two flavonoids extracts from Glycyrrhizae radix inhibit in vitro hepatitis C virus replication2009
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Suda G, Mishima K, Onuki Y, Yamamoto M, Maekawa S, Enomoto N, Kanai T, Tsuchiya K, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 39 Pages: 60-69
- NAID
  10025324061
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein2009
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Nakagawa M, Sekine-Osajima Y, Tasaka-Fujita M, Nishimura-Sakurai Y, Suda G, Karakama Y, Mishima K, Yamamoto M, Watanabe T, Ueyama M, Funaoka Y, Azuma S, Watanabe M
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1727-1737
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq2009
- Author(s)
  Wang SY, Tseng CP, Tsai KC, Lin CF, Wen CY, Tsay HS, Sakamoto N, Tseng CH, Cheng JC
- Journal Title
  
  Biochem BiophysRes Commun
  
  Volume: 385 Pages: 230-235
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cellsin bone marrow2009
- Author(s)
  Fujii T, Kanai T, Tomita T, Nemoto Y,Totsuka T, Sakamoto N, Nakamura T,Tsuchiya K, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol 38(12)
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C2009
- Author(s)
  Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano K, Masaki N, Sugauchi F, Izumi N, Tokunaga K, Mizokami M
- Journal Title
  
  NatGenet
  
  Volume: 41 Pages: 1105-1109
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Musashi-1 suppressesexpression of Paneth cell-specific genes inhuman intestinal epithelial cells2009
- Author(s)
  Murayama M, Okamoto R, Tsuchiya K, Akiyama J, Nakamura T, Sakamoto N, Kanai T and Watanabe M
- Journal Title
  
  Gasroenterology 44
  
  Pages: 173-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.2009
- Author(s)
  Tai AW, Sakamoto N, et al
- Journal Title
  
  Cell Host Microbe. 5
  
  Pages: 298-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C2009
- Author(s)
  Tanaka Y, Nishida N, Sugiyama M, Kurosaki M, Matsuura K, Sakamoto N, Nakagawa M, Korenaga M, Hino K, Hige S, Ito Y, Mita E, Tanaka E, Mochida S, Murawaki Y, Honda M, Sakai A, Hiasa Y, Nishiguchi S, Koike A, Sakaida I, Imamura M, Ito K, Yano K, Masaki N, Sugauchi F, Izumi N, Tokunaga K, Mizokami M
- Journal Title
  
  NatGenet
  
  Volume: 41 Pages: 1105-1109
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Prospects for future therapy of hepatitis C virus infection.2009
- Author(s)
  Sakamoto N, Wu GY
- Journal Title
  
  Future Virology 4
  
  Pages: 453-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Two flavonoidsextracts from Glycyrrhizae radix inhibit in vitrohepatitis C virus replication2009
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Suda G, Mishima K, Onuki Y, Yamamoto M, Maekawa S, Enomoto N, Kanai T, Tsuchiya K and Watanabe M
- Journal Title
  
  Hepatol Res 39
  
  Pages: 60-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein2009
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Nakagawa M, Sekine-Osajima Y, Tasaka-Fujita M, Nishimura-Sakurai Y, Suda G, Karakama Y, Mishima K, Yamamoto M, Watanabe T, Ueyama M, Funaoka Y, Azuma S, Watanabe M
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1727-37
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Signaling pathway via TNFa/NFnB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.2009
- Author(s)
  Onizawa, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Nagaishi T, Sakamoto N, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5Bprotein2009
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Nakagawa M, Sekine-Osajima Y, Tasaka-Fujita M, Nishimura-Sakurai Y, Suda G, Karakama Y, Mishima K, Yamamoto M, Watanabe T, Ueyama M, Funaoka Y, Azuma S, Watanabe M
- Journal Title
  
  Hepatology
  
  Volume: 50(6) Issue: 6 Pages: 1727-37
- DOI
  10.1002/hep.23195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831
[Journal Article] The isomerase active site of cyclophilin A is critical for hepatitis C virus replication.2009
- Author(s)
  Chatterji U, Sakamoto N, et al
- Journal Title
  
  J Biol Chem 284
  
  Pages: 16998-17005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] New therapeutic approaches to hepatitis Cvirus2009
- Author(s)
  Sakamoto N, Watanabe M
- Journal Title
  
  JGastroenterol
  
  Volume: 44 Pages: 643-649
- NAID
  10025175879
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] The isomerase active site of cyclophilin A is critical for hepatitis C virus replication2009
- Author(s)
  Chatterji U, Bobardt M, Selvarajah S, Yang F, Tang H, Sakamoto N, Vuagniaux G, Parkinson T, Gallay P
- Journal Title
  
  J Biol Chem
  
  Volume: 284 Pages: 16998-17005
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Inhibition of intracellular hepatitis C virus replication by nelfinavir and synergistic effect with interferon-alpha.2009
- Author(s)
  Toma S, Sakamoto N, et al
- Journal Title
  
  Journal of Viral Hepatitis 16
  
  Pages: 506-512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] IL-7 is Essential for Lymphopenia-driven Turnover of Colitogenic CD4+ Memory T Cells in Chronic Colitis.2009
- Author(s)
  Tomita T, Sakamoto N, et al
- Journal Title
  
  Eur J Immuno 39
  
  Pages: 2737-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] A functional genomic screen identifies cellular cofactors of hepatitis C virus replication.2009
- Author(s)
  Andrew W. Tai, Yair Benita, Lee F. Peng, Sun-Suk Kim, Naoya Sakamoto, Ramnik J. Xavier, Raymond T. Chung
- Journal Title
  
  Cell Host & Microbe In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.2009
- Author(s)
  Tanaka Y, Sakamoto N, et al
- Journal Title
  
  Nature Genetics 41
  
  Pages: 1105-1109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] New therapeutic approaches to HCV.J2009
- Author(s)
  Naoya Sakamoto, Mamoru Watanabe
- Journal Title
  
  Gastroenterol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by nelfinavir and interferon-a.2009
- Author(s)
  Satoshi Toma, Tsuyoshi Yamashiro, Shingo Arakaki, Joji Shiroma, Tatsuji Maeshiro, Kenji Hibiya, Naoya Sakamoto, Fukunori Kinjo, Masao Tateyama, Jiro Fujita
- Journal Title
  
  Journal of Viral Hepatitis In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Two flavonoids extracts from a herb, Glycyrrhizae radix, inhibit in-vitro hepatitis C virus replication2009
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Suda G, Mishima K, Onuki Y, Yamamoto M, Maekawa S, Enomoto N, Kanai T, Tsuchiya K, Watanabe M
- Journal Title
  
  Hepatology Res 39(1)
  
  Pages: 60-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Bioactivity-guided screening identifies pheophytin a as a potent anti-hepatitis C virus compound from Lonicera hypoglauca Miq.2009
- Author(s)
  Wang SY, Sakamoto N, et al
- Journal Title
  
  Biochem Biophys Res Commun 385
  
  Pages: 230-235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Two flavonoids extracts from Glycyrrhizae radix inhibit in vitro hepatitis C virus replication2009
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Suda G, Mishima K, Onuki Y, Yamamoto M, Maekawa S, Enomoto N, Kanai T, Tsuchiya K, Watanabe M
- Journal Title
  
  Hepatol Res
  
  Volume: 39 Pages: 60-69
- NAID
  10025324061
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2009
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N, et al
- Journal Title
  
  J Gastroentorol (EPub)
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] A functional genomic screen identifies cellular cofactors of hepatitis C virus replication2009
- Author(s)
  Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, Chung RT
- Journal Title
  
  Cell Host Microbe
  
  Volume: 5 Pages: 298-307
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] HCV-associated gene expression and cell signaling pathway in cells with or without HCV replicon and in replicon-cured cells.2009
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N, Megumi Tasaka-Fujita
- Journal Title
  
  J.Gastroentelorogy
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831
[Journal Article] Signaling pathway via TNFa/NFkB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis.2009
- Author(s)
  Onizawa M, Sakamoto N, et al
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein.2009
- Author(s)
  Itsui Y, Sakamoto N(equal contribution), et al
- Journal Title
  
  Hepatology 50
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein.2009
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Nakagawa M, Sekine-Osajima Y, Tasaka-Fujita M, Nishimura-Sakurai Y, Suda G, Karakama Y, Mishima K, Yamamoto M, Watanabe T, Ueyama M, Funaoka Y, Azuma S, Watanabe M
- Journal Title
  
  Hepatology 50
  
  Pages: 1727-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790485
[Journal Article] Signaling pathway via TNFa/NFkB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, Nagano KI, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, TsuchiyaK, Aoki K, Ohya K, Yagita H and Watanabe M
- Journal Title
  
  Am J Physol Gastrntest Liver Physiol (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Two flavonoids extracts from a herb, Glycyrrhizae radix, inhibit in-vitro hepatitis C virus replication.2009
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Suda G, Mishima K, Onuki Y, Yamamoto M, Maekawa S, Enomoto N, Kanai T, Tsuchiya K, Watanabe M
- Journal Title
  
  Hepatoloj Res 39
  
  Pages: 60-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.2009
- Author(s)
  Mizui T, Sakamoto N, et al
- Journal Title
  
  J Gastroenterol 45
  
  Pages: 195-203
- NAID
  10027214573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein2009
- Author(s)
  Itsui Y, Sakamoto N, Megumi Tasaka- Fujita
- Journal Title
  
  Hepatology 50
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590831
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.2009
- Author(s)
  Totsuka T, Sakamoto N, et al
- Journal Title
  
  J Immunol. 182
  
  Pages: 6079-6087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Hepatitis C virus NS5A protein increases hepatic lipid accumulation via induction of activation and expression of PPARgamma.2009
- Author(s)
  Kim K, Sakamoto N, et al
- Journal Title
  
  FEBS Letter 583
  
  Pages: 2720-2726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Antiviral effects of the interferon-induced protein GBP-1 and its interaction with the hepatitis C virus NS5B protein.2009
- Author(s)
  Itsui Y, Sakamoto N(equal contribution)
- Journal Title
  
  Hepatology 50
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Comparison of HCV-associated gene expression and cell signaling pathways in cells with or without HCV replicon and in replicon-cured cells.2009
- Author(s)
  Nishimura-Sakurai Y, Sakamoto N, et al
- Journal Title
  
  J Gastroentorol
- NAID
  10027216127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590832
[Journal Article] Adoptive immunotherapy with liver allograft-derived lymphocytes induces anti-HCV activity after liver transplantation in humans and humanized mice.2009
- Author(s)
  Ohira M, Sakamoto N, et al
- Journal Title
  
  J Clin Invest 119
  
  Pages: 3226-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] New therapeutic approaches to hepatitis C virus.2009
- Author(s)
  Sakamoto N, Watanabe M.
- Journal Title
  
  J Gastroenterol. 44
  
  Pages: 643-649
- NAID
  10025175879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Long-lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis.2009
- Author(s)
  Nemoto Y, Sakamoto N, et al
- Journal Title
  
  J Immunol 183
  
  Pages: 5059-5068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Prospects for future therapy of hepatitis Cvirus infection2009
- Author(s)
  Sakamoto N, Wu GY
- Journal Title
  
  Future Virology
  
  Volume: 4 Pages: 453-462
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] MyD88-dependentpathway in T cells directly modulates theexpansion of colitogenic CD4+ T cells in chroniccolitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, SakamotoN, Akira S and Watanabe M
- Journal Title
  
  J Immunol 180
  
  Pages: 5291-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Immunosenescent colitogenic CD4+ T cells convert to regulatory cells and suppress colitis.2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Effects of immunosuppressants on the progression of hepatitis C in hepatitis C virus-positive renal transplantation and the usefulness of interferon therapy.2008
- Author(s)
  Nanmoku K, Imaizumi R, Tojimbara T, Nakajima I, Fuchinoue S, Sakamoto N, Watanabe M, Teraoka S
- Journal Title
  
  Transplant Proc 40
  
  Pages: 2382-2385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA.2008
- Author(s)
  Sakamoto N, Tanabe Y, Yokota T, Saito K, Sekine-Osajima Y, Nakagawa M, Itsui Y, Tasaka M, Sakurai Y, Chen CH, Yano M, Ohkoshi S, Aoyagi Y, Maekawa S, Enomoto N, Kohara M, Watanabe M
- Journal Title
  
  J Gastro Hepatol 23
  
  Pages: 1437-1447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Two flavonoids extracts from a herb, Glycyrrhizae radix, inhibit in-vitrohepatitis C virus replication.2008
- Author(s)
  Sakamoto N, Sekine-Osajima Y, Nakagawa M, Itsui Y, Chen CH, Watanabe M, et. al.
- Journal Title
  
  Hepatology Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Effects of immunosuppressantson the progression of hepatitis C in hepatitis Cvirus-positive renal transplantation and theusefulness of interferon therapy2008
- Author(s)
  Nanmoku K, Imaizumi R, Tojimbara T, Nakajima I, Fuchinoue S, Sakamoto N, Watanabe M and Teraoka S
- Journal Title
  
  Transplant Proc 40
  
  Pages: 2382-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow2008
- Author(s)
  Fujii T, Tomita T, Kanai T, Nemoto Y,Totsuka T, Sakamoto N, Nakamura T, TsuchiyaK, Okamoto R and Watanabe M
- Journal Title
  
  EurJ Immunol 38
  
  Pages: 3290-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Griseofulvin, an oral antifungal agent, suppresses HCV replication in vitro.2008
- Author(s)
  Jin H, Wakita T, Sakamoto N, Enomoto N, et. al.
- Journal Title
  
  Hepatology Research (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Immunosenescent colitogenicCD4(+) T cells convert to regulatory cells and Dsuppress colitis2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R and Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1275-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Continuous generation ofcolitogenic CD4(+) T cells in persistent colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y,Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N and Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1264-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Targeting lipid metabolism in the treatment of hepatitis C.2008
- Author(s)
  Amemiya F, Maekawa S, Itakura Y, Kanayama A, Takano S, Yamaguchi T, Itakura J, Kitamura T, Inoue T, Sakamoto M, Yamauchi K, Okada S, Sakamoto N, Enomoto N
- Journal Title
  
  J Infect Dis 368
  
  Pages: 361-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Proteasomal degradation ofAtoh1 by aberrant Wnt signaling maintains theundifferentiated state of colon cancer2008
- Author(s)
  Aragaki M, Tsuchiya K, Okamoto R,Yoshioka S, Nakamura T, Sakamoto N, Kanai T and Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 923-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Continuous generation of colitogenic CD4+ T cells may be one of the mechanisms to persist colitis.2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N. Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Targeting lipid metabolism in the treatment of hepatitis C2008
- Author(s)
  Amemiya F, Maekawa S, Itakura Y,Kanayama A, Takano S, Yamaguchi T,Itakura J, Kitamura T, Inoue T, Sakamoto M,Yamauchi K, Okada S, Sakamoto N, Enomoto N
- Journal Title
  
  J Infect Dis 197(3)
  
  Pages: 361-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Potential relevance of cytoplasmic viral sensors and related regulators involving innate immunity in antiviral response.2008
- Author(s)
  Asahina Y, Izumi N, Hirayama I, Tanaka T, Sato M, Yasui Y, Komatsu N, Umeda N, Hosokawa T, Ueda K, Tsuchiya K, Nakanishi H, Itakura J, Kurosaki M, Enomoto N, Tasaka M, Sakamoto N, Miyake S
- Journal Title
  
  Gastroenterology 134
  
  Pages: 1396-1405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Systemic, but not intestinal, IL-7is essential for the persistence of chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N and Watanabe M
- Journal Title
  
  J Immunol 180
  
  Pages: 383-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Effects of immunosuppressants on the progression ofhepatitis C in hepatitis C virus-positive renal transplantation and the usefulness of interferon therapy2008
- Author(s)
  Nanmoku K, Imaizumi R, Tojimbara T,Nakajima I, Fuchinoue S, Sakamoto N, Watanabe M, Teraoka S
- Journal Title
  
  Transplant Proc 40(7)
  
  Pages: 2382-2385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Development of plaque assays forhepatitis C virus-JFH1 strain and isolation ofmutants with enhanced cytopathogenicity and replication capacity2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N, MishimaK, Nakagawa M, Itsui Y, Tasaka M,Nishimura-Sakurai Y, Chen CH, Kanai T, Tsuchiya K, Wakita T, Enomoto N and Watanabe M
- Journal Title
  
  Virology 371
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Blockade of NKG2D signaling prevents the development ofmurine CD4+ T cell-mediated colitis2008
- Author(s)
  Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, OkumuraK, Yagita H and Watanabe M
- Journal Title
  
  Am J Physiol Gastro intest Liver Physiol 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Negative feedback regulation of colitogenicCD4(+) T cells by increased granulopoiesis2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T,Okamoto R, Tsuchiya K, Nakamura T, SakamotoN, Fukuda T, Miura O, Yagita H and Watanabe M
- Journal Title
  
  In flamm Bowel Dis
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Potential relevance of cytoplasmic viralsensors and related regulators involving innate immunity in antiviral response2008
- Author(s)
  Asahina Y, Izumi N, Hirayama I, Tanaka T,Sato M, Yasui Y, Komatsu N, Umeda N,Hosokawa T, Ueda K, Tsuchiya K,Nakanishi H, Itakura J, Kurosaki M,Enomoto N, Tasaka M, Sakamoto N, Miyake S
- Journal Title
  
  Gastroenterology 134(5)
  
  Pages: 1396-1405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Proteasomal degradation of Atohl by aberrant Wnt signaling maintains the undifferentiated state of colon cancer.2008
- Author(s)
  Aragaki M, Tsuchiya K, Okamoto R, Yoshioka S, Nakamura T, Sakamoto N, Kanai T, Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 923-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA.2008
- Author(s)
  Sakamoto N, Chen CH, Watanabe M, et. al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA2008
- Author(s)
  Sakamoto N, Tanabe Y, Yokota T, Saito K,Sekine-Osajima Y, Nakagawa M, Itsui Y,Tasaka M, Sakurai Y, Chen CH, Yano M,Ohkoshi S, Aoyagi Y, Maekawa S, Enomoto N, Kohara M, Watanabe M
- Journal Title
  
  J Gastro Hepatol 23(9)
  
  Pages: 1437-1447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Colitogenic CD4(+) effector-memory T cellsactively recirculate in chronic colitic mice2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T,Nozaki K, Okamoto R, Tsuchiya K, Nakamura T,Sakamoto N, Totsuka T and Watanabe M
- Journal Title
  
  In flamm Bowel Dis
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Development of plaque assays for hepatitis C virus and isolation of mutants with enhanced cytopathogenicity and replication capacity.2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N (equal contribution), Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Kanai T, Tsuchiya K, Wakita T, Enomoto N, Watanabe M
- Journal Title
  
  Virology 368
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Proteasomal degradation of Atohl by aberrant Wnt signaling maintains the undifferentiated state of colon cancer.2008
- Author(s)
  Aragaki M, Sakamoto N, Kanai T, et. al.
- Journal Title
  
  Biochem Biophys Res Commun (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity.2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Chen CH, Watanabe M, et. al.
- Journal Title
  
  Virology 371
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Griseofulvin, an oral antifungal agent, suppresses HCV replication in vitro2008
- Author(s)
  Jin H, Yamashita A, Maekawa S, Yang P, HeL, Takayanagi S, Wakita T, Sakamoto N,Enomoto N, Ito M
- Journal Title
  
  Hepatology Res 38(9)
  
  Pages: 909-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Development of plaque assaysfor hepatitis C virus and isolation of mutantswith enhanced cytopathogenicity and replication capacity2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N(equal contribution), Nakagawa M, Itsui Y, TasakaM, Nishimura-Sakurai Y, Chen CH, Kanai T,Tsuchiya K, Wakita T, Enomoto N and Watanabe M
- Journal Title
  
  Virology 371
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Griseofulvin, an oral antifungal agent, suppresses HCV replication in vitro.2008
- Author(s)
  Jin H, Yamashita A, Maekawa S, Yang P, He L, Takayanagi S, Wakita T, Sakamoto N, Enomoto N, Ito M
- Journal Title
  
  Hepatology Res 38
  
  Pages: 909-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow.2008
- Author(s)
  Fujii T, Kanai T, Tomita T, Nemoto Y, Totsuka T, Sakamoto N, Nakamura T, Tsuchiya K, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer2008
- Author(s)
  Aragaki M, Tsuchiya K, Okamoto R,Yoshioka S, Nakamura T, Sakamoto N,Kanai T, Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun 368(4)
  
  Pages: 923-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Systemic, but not intestinal,IL-7 is essential for the persistence ofchronic colitis2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T,Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
- Journal Title
  
  J immunol 180(1)
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] MyD88-dependent Pathway in T Cells Directly Modulates the Expansion of Colitogenic CD4+ T Cells in Chronic Colitis.2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N. Akira S, Watanabe M
- Journal Title
  
  J Immunol 180
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Bone morphogenetic protein-7 and interferon-alpha synergistically suppress hepatitis C virus replicon2007
- Author(s)
  Sakamoto N, Yoshimura M, Kimura T, Toyama K, Sekine-Osajima Y, Watanabe M, Muramatsu M
- Journal Title
  
  Biochem Biophys Res Commun 357
  
  Pages: 467-473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Human Cord Blood Cells Transplanted into Chronic-Damaged Liver Exhibit Similar Characteristics to Functional Hepatocytes2007
- Author(s)
  Kakinuma S, Asahina K, Okamura K,Teramoto K, Tateno C, Yoshizato K, TanakaY, Yasumizu T, Sakamoto N, Watanabe M,Teraoka H
- Journal Title
  
  Transplantation Proceedings 39
  
  Pages: 240-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] HCV nonstructural proteins responsible for suppression of RIG-I/Cardif-induced interferon response2007
- Author(s)
  Tasaka M, Sakamoto N(equal contribution), Itakura Y, Nakagawa M, Itusi Y,Sekine-Osajima Y, Nishimura-Sakurai Y,Chen CH, Yoneyama M, Fujita T, Wakita T,Maekawa S, Enomoto N, Watanabe M
- Journal Title
  
  J Gen Virol 88
  
  Pages: 3323-3333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Human cord blood cells transplanted into chronic-damaged liver exhibit similar characteristics to functional hepatocytes.2007
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  Transplantation Proceedings 39・1
  
  Pages: 240-243
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Inhibition of hepatitis C virus infection and expression in vitro and in vivo by recombinant adenovirus expressing short hairpin RNA2007
- Author(s)
  Sakamoto N, Tanabe Y, Yokota T, Satoh K, Sekine-Osajima Y, Nakagawa M, Itsui Y, Tasaka M, Sakurai Y, Chen CH, Yano M, Ohkoshi S,Aoyagi Y, Maekawa S, Enomoto N, Kohara M and Watanabe M
- Journal Title
  
  J Gastroenterol Hepatol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] Identification of novel epoxide inhibitors of HCV replication、. a high-throughput screen2007
- Author(s)
  Peng LF, Kim SS, Matchacheep S, Lei X, SuS, Lin W, Runguphan W, Choe WH, Sakamoto N, Ikeda M, Kato N, Beeler AB,Porco JA Jr, Schreiber SL and Chung RT
- Journal Title
  
  Antimicrob Agent Chemother 51(10)
  
  Pages: 3756-3759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Human cord blood cells transplanted into chronic-damaged liver exhibit similar characteristics to functional hepatocytes.2007
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  Transplantation Proceedings 39(1)
  
  Pages: 240-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response2007
- Author(s)
  Tasaka M, Sakamoto N, Itakura Y,Nakagawa M, Itsui Y, Sekine-Osajima Y,Nishimura-Sakurai Y, Chen CH, Yoneyama M,Fujita T, Wakita T, Maekawa S, Enomoto N and Watanabe M
- Journal Title
  
  J Gen Virol 88
  
  Pages: 3323-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] A cell-based, high-throughput screen for small molecule regulators of HCV replication2007
- Author(s)
  Kim SS, Peng LF, Lin W, Choe WH,Sakamoto N, Schreiber SL, Ikeda M, Kato N, Chung RT
- Journal Title
  
  Gastroenterology2007 132
  
  Pages: 311-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] Human cord blood cells transplanted into chronic-damaged liver exhibit similar characteristics to functional hepatocytes.2007
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  Transplantation Proceedings. 39・1
  
  Pages: 240-243
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Hepatitis C virus non-structural proteins responsible for suppression of the RIG-I/Cardif-induced interferon response.2007
- Author(s)
  Tasaka M, Sakamoto N, Chen CH, Watanabe M, et. al.
- Journal Title
  
  Journal of General Virology 88
  
  Pages: 3323-3333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] A cell-based, high-throughput screen for small molecule regulators of HCV replication2007
- Author(s)
  Kim SS, Sakamoto N, Chung RT et al.
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 311-320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Bone morphogenetic protein-7 and interferon-alpha synergistically suppresshepatitis C virus replicon2007
- Author(s)
  Sakamoto N, Yoshimura M, Kimura T, Toyama K, Sekine-Osajima Y, Watanabe M and Muramatsu M
- Journal Title
  
  Biochem Biophys Res Commun 357
  
  Pages: 467-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590752
[Journal Article] A cell-based, high-throughput screen for small molecule regulators of HCV replication,2007
- Author(s)
  Kim SS, Sakamoto N, Chung RT, et al.
- Journal Title
  
  Gastroenterology 132
  
  Pages: 311-320
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication2006
- Author(s)
  Itsui Y, Sakamoto N, et al.
- Journal Title
  
  Journal of Viral Hepatitis (In press)
- Data Source
  KAKENHI-PROJECT-17015014
[Journal Article] Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor-3.2006
- Author(s)
  Yamashiro T, Sakamoto N, Nakagawa M, Itsui Y, et al.
- Journal Title
  
  J Gastroenterol. 41
  
  Pages: 750-757
- NAID
  10018255879
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication.2006
- Author(s)
  Itsui Y, Sakamoto N, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13・10
  
  Pages: 690-700
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3.2006
- Author(s)
  Yamashito T, Sakamoto N, Chen CH, Watanabe M, et al.
- Journal Title
  
  Journal of Gastroenterology 41(8)
  
  Pages: 750-757
- NAID
  10018255879
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Maekawa S, Sakamoto N, Watanabe H, Tanabe Y, et al.
- Journal Title
  
  J Viral Hepatitis 13
  
  Pages: 582-582
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication2006
- Author(s)
  Itsui Y, Sakamoto N, et al.
- Journal Title
  
  Journal of Viral Hepatitis (in press)
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Sakamoto N, Chen CH, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13(9)
  
  Pages: 582-590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor-3.2006
- Author(s)
  Yamashiro T, Sakamoto N, Nakagawa M, Itsui Y, et al.
- Journal Title
  
  J Gastroenterol 41
  
  Pages: 750-757
- NAID
  10018255879
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] A cell-based, high-throughput screen for small molecule regulators of HCV replication.2006
- Author(s)
  Kim SS, Sakamoto N, Chung RT et al.
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 311-320
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication.2006
- Author(s)
  Itsui Y, Sakamoto N, Kanazawa N, Nakagawa M, et al.
- Journal Title
  
  J Viral Hepatitis. 13
  
  Pages: 690-700
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Maekawa S, Sakamoto N, Watanabe H, et al.
- Journal Title
  
  J Viral Hepatitis. 13
  
  Pages: 582-582
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication.2006
- Author(s)
  Itsui Y, Sakamoto N, Kurosaki M, Kanazawa N, Tanabe Y, Koyama T, Takeda Y, Nakagawa M, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13
  
  Pages: 690-700
- Data Source
  KAKENHI-PROJECT-18590721
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Maekawa S, Sakamoto N, Watanabe H, Tanabe Y, Chen CH, Nakagawa M, Kakinuma S, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13
  
  Pages: 582-590
- Data Source
  KAKENHI-PROJECT-18590721
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Sakamoto N, Chen CH, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Viral Hepatitis. 13・9
  
  Pages: 582-590
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modules hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Maekawa S, Sakamoto N, Watanabe H, et al.
- Journal Title
  
  J Viral Hepatitis. 13
  
  Pages: 582-582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.2006
- Author(s)
  Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, et al.
- Journal Title
  
  Hepatology Res. 34
  
  Pages: 41-49
- NAID
  10020406147
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Site-specific mutation of interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication2006
- Author(s)
  Kohashi T, Sakamoto N, et al.
- Journal Title
  
  Journal of Viral Hepatitis (in press)
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.2006
- Author(s)
  Kohashi T, Sakamoto N, Chen CH, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Viral Hepatitis 13・9
  
  Pages: 582-590
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Expressional screening of interferon-stimulated genes for antiviral activity against hepatitis C virus replication.2006
- Author(s)
  Itsui Y, Sakamoto N, Kurosaki M, Kanazawa N, Nakagawa M, et al.
- Journal Title
  
  J Viral Hepatitis 13
  
  Pages: 690-700
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.2006
- Author(s)
  Koyama T, Sakamoto N, Tanabe Y, Nakagawa M, Itsui Y, et al.
- Journal Title
  
  Hepatology Res 34
  
  Pages: 41-49
- NAID
  10020406147
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3.2006
- Author(s)
  Yamashiro T, Sakamoto N, Chen CH, Watanabe M, et al.
- Journal Title
  
  Journal of Gastroenterology. 41・8
  
  Pages: 750-757
- NAID
  10018255879
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Negative regulation of intracellular hepatitis C virus replication by interferon regulatory factor 3.2006
- Author(s)
  Yamashiro T, Sakamoto N, Chen CH, Watanabe M, et al.
- Journal Title
  
  Journal of Gastroenterology 41・8
  
  Pages: 750-757
- NAID
  10018255879
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication2006
- Author(s)
  Koyama T, Sakamoto N, et al.
- Journal Title
  
  Hepatology Research 34
  
  Pages: 41-49
- NAID
  10020406147
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Characteristic sequence changes of hepatitis C virus genotype 2b associated with sustained biochemical response to IFN therapy2005
- Author(s)
  Tanabe Y, Sakamoto N, et al.
- Journal Title
  
  Journal of Viral Hepatitis 12
  
  Pages: 251-261
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Enhancement of mitochondrial gene expression in the liver of primary biliary cirrhosis.2005
- Author(s)
  Chen CH, Sakamoto N, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Hepatology Research 31(1)
  
  Pages: 24-30
- NAID
  10015455952
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N, Kakinuma S, Watanabe M et al.
- Journal Title
  
  Gastroenterology 129(3)
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590581
[Journal Article] Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin.2005
- Author(s)
  Itakura J, Nagayama K, Enomoto N, Hamano K, Sakamoto N, Fanning LJ, Kenny-Walsh E, Shanahan F, Watanabe M
- Journal Title
  
  J Viral Hepat. 12
  
  Pages: 594-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Characteristic sequence changes of hepatitis C virus genotype 2b associated with sustained biochemical response to IFN therapy.2005
- Author(s)
  Tanabe Y, Nagayama K, Enomoto N, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  J Viral Hapat. 12
  
  Pages: 251-261
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Enhancement of Mitochondrial Gene Expression in the Liver of Primary Biliary Cirrhosis.2005
- Author(s)
  Chen CH, Nagayama K, Enomoto N, Miyasaka Y, Kurosaki M, Sakamoto N, Meakawa S, Kakinuma S, Ideda T, Izumi N, Sato C, Watanabe M
- Journal Title
  
  Hepatology Res. 31
  
  Pages: 24-30
- NAID
  10015455952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N (equal contribution), Tanabe Y, Koyama T, Itsui Y, Watanabe M, et al.
- Journal Title
  
  Gastroenterology. 129
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N, Chen CH, Kakinuma S, Watanabe M et al.
- Journal Title
  
  Gastroenterology 129(3)
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-α plus ribavirin combination therapy.2005
- Author(s)
  Hamano K, Sakamoto N, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology 20(9)
  
  Pages: 1401-1409
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Suppression of hepatitis C virus replication by cycosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N, Chen CH, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Gastroenterology 129(3)
  
  Pages: 1031-1041
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N, Tanabe Y, Koyama T, Itsui Y, Takeda Y, Chen CH, Kakinuma S, Oooka S, Maekawa S, Enomoto N, Watanabe M
- Journal Title
  
  Gastroenterology 129(3)
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Mutations in the NS5B region of the hepatitis C virus genome correlate with clinical outcomes of interferon-alpha plus ribavirin combination therapy.2005
- Author(s)
  Hamano K, Sakamoto N, et al.
- Journal Title
  
  Journal of Gastroenterology and Hepatology 20
  
  Pages: 1401-1409
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Characteristic sequence changes of hepatitis C virus genotype 2b associated with sustained biochemical response to IFN therapy.2005
- Author(s)
  Tanaka Y, Nagayama K, Enomoto N, Izumi N, Tazawa J, Kurosaki M, Sakamoto N, Sato C, Watanabe M
- Journal Title
  
  J viral Hepat. 12
  
  Pages: 251-261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Enhancement of Mitochondrial Gene Expression in the Liver of Primary Biliary Cirrhosis.2005
- Author(s)
  Chen CH, Nagayama K, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  Hepatology Res. 31
  
  Pages: 24-30
- NAID
  10015455952
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N, Chen CH, Kakinuma S, Watanabe M, et al.
- Journal Title
  
  Gastroenterology. 129・3
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590625
[Journal Article] Viral load change and sequential evolution of entire hepatitis C virus genome in Irish recipients of single source-contaminated anti-D immunoglobulin.2005
- Author(s)
  Itakura J, Nagayama K, Sakamoto N, Watanabe M, et al.
- Journal Title
  
  J Viral Hapat. 12
  
  Pages: 594-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockade of cyclophilins2005
- Author(s)
  Nakagawa M, Sakamoto N, et al.
- Journal Title
  
  Gastroenterology 129
  
  Pages: 1031-1041
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Suppression of hepatitis C virus replication by cyclosporin A is mediated by blockage of cyclophilins.2005
- Author(s)
  Nakagawa M, Sakamoto N (equal contribution), Tanabe Y, Koyama T.Itsui Y, Takeda Y, Chen CH, Kakinuma S, Oooka S, Maekawa S, Enomoto N, Watanabe M
- Journal Title
  
  Gastroenterology. 129(3)
  
  Pages: 1031-1041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590626
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A2004
- Author(s)
  Sakamoto N., Oooka M, et al.
- Journal Title
  
  Biochem Biophys Res Com 313
  
  Pages: 42-47
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor-I2004
- Author(s)
  Kanazawa N, Sakamoto N, et al.
- Journal Title
  
  J Virol 2004;78(18):9713-9720 78(18)
  
  Pages: 9713-9720
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor 1.2004
- Author(s)
  Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, Itsui Y, Yamashiro T, Tanabe Y, Maekawa S, Nakagawa M, Chen CH, Kakinuma S, Oshima S, Nakamura T, Kato T, Wakita T, Watanabe M.
- Journal Title
  
  J virol. 78
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A.2004
- Author(s)
  Nakagawa M, Sakamoto N, Enomoto N, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 313・1
  
  Pages: 42-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Changes of HCV quasispecies during combination therapy with interferon and ribavirin.2004
- Author(s)
  Ueda E, Enomoto N, Sakamoto N, Hamano K, Sato C, Izumi N, Watanabe M.
- Journal Title
  
  Hepatol Res. 29
  
  Pages: 89-96
- NAID
  10018024225
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A2004
- Author(s)
  Sakamoto N. et al.
- Journal Title
  
  Biochem Biophys Res Com 313
  
  Pages: 42-47
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4 : Evidence for impaired Skp2-dependent degradation of, p27 in terminal differentiation.2004
- Author(s)
  Tamamori-Adachi M, Hayashida K, Nobori K, Omizu C, Yamada K, Sakamoto N, Kamura T, Fukuda K, Ogawa S, Nakayama KI, Kitajima S
- Journal Title
  
  J Biol Chem 279
  
  Pages: 50429-50436
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon-alpha.2004
- Author(s)
  Tanabe Y, Sakamoto N, Enomoto N, Kurosaki M, Ueada E, Maekawa S, Yamashiro T, Nakagawa M, Chen CH, Kanazawa N, Watanabe M.
- Journal Title
  
  J Infect Dis 189
  
  Pages: 1129-1139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor-12004
- Author(s)
  Kanazawa N, Sakamoto N, et al.
- Journal Title
  
  J Virol 78(18)
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells.2004
- Author(s)
  Maekawa S, Enomoto N, Sakamoto N, Kurosaki M, Ueda E, Kohashi T, Watanabe H, Chen CH, Yamashiro T, Tanabe Y, Kanazawa N, Nakagawa M, Sato C, Watanabe M.
- Journal Title
  
  J Viral Hepat. 11
  
  Pages: 394-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A2004
- Author(s)
  Sakamoto N, et al.
- Journal Title
  
  Biochem Biophys Res Com 313
  
  Pages: 42-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor-12004
- Author(s)
  Kanazawa N, Sakamoto N, et al.
- Journal Title
  
  J Virol 2004;78(18):9713-9720 78(18)
  
  Pages: 9713-9720
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon-alpha.2004
- Author(s)
  Tanabe Y, Sakamoto N, Enomoto N, Kurosaki M, Ueda E, Maekawa S, Yamashiro T, Nakagawa M, Chen CH, Kanazawa N, Kakinuma S, Watanabe M.
- Journal Title
  
  J Infect Dis. 189
  
  Pages: 1129-1139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4:Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation2004
- Author(s)
  Tamamori-Adachi M, Sakamoto N. et al.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 50429-50436
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon-alpha2004
- Author(s)
  Sakamoto N, et al.
- Journal Title
  
  J Infect Dis 189
  
  Pages: 1129-1139
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Specific inhibition of hepatitis C virus replication by cyclosporin A.2004
- Author(s)
  Nakagawa M, Sakamoto N, Enomoto N, Tanabe Y, Kanazawa N, Koyama T, Kurosaki M, Maekawa S, Yamashiro T, Chen CH, Itsui Y, Kakinuma S, Watanabe M.
- Journal Title
  
  Biochem Biophys Res Commun. 313
  
  Pages: 42-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Introduction of NS5A Mutations Enables Subgenomic HCV-Replicon Derived from Chimpanzee-Infectious HC-J4 Isolate to Replicate Efficiently in Huh-7 Cells.2004
- Author(s)
  Maekawa S, Enomoto N, Sakamoto N, Kurosaki M, Ueda E, Kohashi T, Watanabe H, Chen CH, Yamashiro T, Tanabe Y, Kanazawa N, Nakagawa M, Sato C, Watanabe M.
- Journal Title
  
  J Viral Hepatitis 11
  
  Pages: 394-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Introduction of NS5A Mutations Enables Subgenomic HCV-Replicon Derived from Chimpanzee-Infectious HC-J4 Isolate to Replicate Efficiently in Huh-7 Cells.2004
- Author(s)
  Maekawa S, Sakamoto N, et al.
- Journal Title
  
  J Viral Hepatitis 11
  
  Pages: 394-403
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Introduction of NS5A Mutations Enables Subgenomic HCV-Replicon Derived from Chimpanzee-Infectious HC-J4 Isolate to Replicate Efficiently in Huh-7 Cells.2004
- Author(s)
  Maekawa S, Sakamoto N, et al.
- Journal Title
  
  J Viral Hepatitis 11
  
  Pages: 394-403
- Data Source
  KAKENHI-PROJECT-16590580
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon-alpha2004
- Author(s)
  Sakamoto N, et al.
- Journal Title
  
  J Infect Dis 189
  
  Pages: 1129-1139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor 1.2004
- Author(s)
  Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, et al.
- Journal Title
  
  J Virol. 78・18
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Regulation of hepatitis C virus replication by interferon regulatory factor-1.2004
- Author(s)
  Kanazawa N, Kurosaki M, Sakamoto N, Enomoto N, Itsui Y, Yamashiro T, Tanabe Y, Maekawa S, Nakagawa M, Chen CH, Oshima S, Nakamura T, Kato T, Wakita T, Watanabe M.
- Journal Title
  
  J Virol 78(18)
  
  Pages: 9713-9720
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by combination of ribavirin and interferon- alpha.2004
- Author(s)
  Tanabe Y, Sakamoto N, Enomoto N, et al.
- Journal Title
  
  J Infect Dis. 189・7
  
  Pages: 1129-1139
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370175
[Journal Article] Hepatitis C virus NS5A protein inhibits TNF-alpha mediated apontosis in HUH7 Cells.2003
- Author(s)
  Miyasaka Y, Sakamoto N, et al.
- Journal Title
  
  J Infect Dis 188
  
  Pages: 1537-1544
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived siRNAs2003
- Author(s)
  Sakamoto N, Yokota T, et al.
- Journal Title
  
  EMBO Reports 4
  
  Pages: 602-608
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived siRNAs2003
- Author(s)
  Sakamoto N, Yokota T, et al.
- Journal Title
  
  EMBO Roports 4
  
  Pages: 602-608
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived siRNAs.2003
- Author(s)
  Yokota T, Sakamoto N, Enomoto N, Tanabe Y, Miyagishi M, Maekawa S, Ye L, Kurosaki M, Taira K, Watanabe M, Mizusawa H.
- Journal Title
  
  EMBO Reports. 4
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Hepatitis C virus NS5A protein inhibits TNF-alpha mediated apoptosis in HUH7 Cells.2003
- Author(s)
  Miyasaka Y, Sakamoto N, et al.
- Journal Title
  
  J Infect Dis 188
  
  Pages: 1537-1544
- Data Source
  KAKENHI-PROJECT-15590629
[Journal Article] Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladia
- Author(s)
  Yamashita A, Abdus K, Furuta A, Matsuda Y, Fujita O, Tani H, Fujita Y, Fujimoto Y, Ikeda M, Kato N, Sakamoto N, Maekawa S, Enomoto N, Nakakoshi M, Tsubuki M, Sekiguchi Y, Thuneda S, Akimitsu N, Noda N, Tanaka J, Moriishi K
- Journal Title
  
  Marine Drugs
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21390226
[Journal Article] Studies on virus kinetics using infectious fluorescence-tagged hepatitis C virus cell culture
- Author(s)
  Yamamoto M, Sakamoto N, Nakamura T, Itsui Y, Nakagawa M, Nishimura-Sakurai Y, Kakinuma S, Azuma S, Kato T, Wakita T, Watanabe M
- Journal Title
  
  Hepatol Res
- Data Source
  KAKENHI-PROJECT-21590833
[Journal Article] Synergistic inhibition of intracellular hepatitis C virus replication by nelfinavir and interferon-α
- Author(s)
  Satoshi Toma, Tsuyoshi Yamashiro, ShingoArakaki, Joji Shiroma, Tatsuji Maeshiro, Kenji Hibiya, Naoya Sakamoto, FukunoriKinjo, Masao Tateyama, Jiro Fujita
- Journal Title
  
  Journal of Viral Hepatitis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Journal Article] A functional genomic screen identifies cellular cofactors of hepatitis C virus replication
- Author(s)
  Andrew W. Tai, Yair Benita, Lee F. Peng, Sun-Suk Kim, Naoya Sakamoto, Ramnik J.Xavier, Raymond T. Chung
- Journal Title
  
  Cell Host & Microbe (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390196
[Patent] C型肝炎ウイルスの増殖を抑制する医薬組成物2011
- Inventor(s)
  坂本直哉、渡辺守、北詰晶子、萩原正敏、奥野友紀子
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Number
  2011-194082
- Filing Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21590832
[Patent] C型肝炎ウイルスの増殖を抑制する医薬組成物2011
- Inventor(s)
  坂本直哉、渡辺守、北詰晶子、萩原正敏、奥野友紀子
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Number
  2011-194082
- Filing Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21390226
[Patent] C型肝炎ウイルスの増殖を抑制する医薬組成物2011
- Inventor(s)
  坂本直哉、渡辺守、北詰晶子、萩原正敏、奥野友紀子
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Number
  2011-194082
- Filing Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21590831
[Patent] C型肝炎ウイルスの増殖を抑制する医薬組成物2011
- Inventor(s)
  坂本直哉、渡辺守、北詰晶子、萩原正敏、奥野友紀子
- Industrial Property Rights Holder
  東京医科歯科大学
- Industrial Property Number
  2011-194082
- Filing Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-22659145
[Patent] 米国特許仮出願2005
- Inventor(s)
  坂本直哉
- Industrial Property Rights Holder
  坂本直哉
- Filing Date
  2005-05-23
- Data Source
  KAKENHI-PROJECT-17590626
[Patent] C型肝炎ウイルスのタンパク質合成及び/又はC型肝炎ウイルスの複製を抑制することができる二本鎖オリゴヌクレオチド2003
- Inventor(s)
  横田隆徳、榎本信幸、坂本直哉、多比良和誠、宮岸真
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究
- Industrial Property Number
  2003-104940
- Filing Date
  2003-05-11
- Data Source
  KAKENHI-PROJECT-19390196
[Patent] HCVのタンパク質合成およびHCVの複製を阻害できる2本鎖オリゴヌクレオチド2003
- Inventor(s)
  横田隆徳, 坂本直哉, 他
- Industrial Property Rights Holder
  横田隆徳
- Filing Date
  2003-05-01
- Data Source
  KAKENHI-PROJECT-15590629
[Patent] HCVのタンパク質合成およびHCVの複製を阻害できる2本鎖オリゴヌクレオチド2003
- Inventor(s)
  横田隆徳, 坂本直哉
- Industrial Property Rights Holder
  横田隆徳
- Filing Date
  2003-05-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590629
[Presentation] 肝癌に対する新世代マイクロ波凝固療法の治療成績2022
- Author(s)
  中井正人, 吉田苑永, 細田峻一, 久保彰則, 得地祐匡, 北潟谷隆, 山田錬, 重沢拓,荘拓也, 須田剛生, 森川賢一, 小川浩司, 坂本直哉.
- Organizer
  第130回日本消化器病学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 再活性化が疑われた急性E型肝炎の1例2022
- Author(s)
  久保彰則, 小川浩司, 吉田苑永, 細田峻一, 得地祐匡, 北潟谷隆, 山田錬, 重沢拓, 中井正人, 荘拓也, 須田剛生, 森川賢一, 石田勢津子, 坂本直哉
- Organizer
  第130回日本消化器病学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 当院における切除不能肝細胞癌に対するアテゾリズマブ＋ベバシズマブ療法の使用経験2021
- Author(s)
  吉田苑永, 荘拓也, 久保彰則, 得地祐匡, 細田峻一, 北潟谷隆, 山田錬, 中井正人,須田剛生, 森川賢一, 小川浩司, 坂本直哉
- Organizer
  第129回日本消化器病学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] Lenvatinib加療後にCRに至りconversion surgeryを施行した肝内多発転移を伴う肝細胞癌の1例2021
- Author(s)
  細田峻一, 中井正人, 吉田苑永, 久保彰則, 得地祐匡, 北潟谷隆, 山田錬, 荘拓也, 須田剛生, 森川賢一, 小川浩司, 坂本直哉, 岡崎ななせ, 大塚拓也, 三橋智子
- Organizer
  第129回日本消化器病学会北海道地方会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 部分的脾動脈塞栓術(PSE), バルーン閉塞下逆行性経静脈的塞栓術(BRTO)の肝予備能, 線維化マーカー, 予後への影響2021
- Author(s)
  5.中井正人, 小川浩司, 坂本直哉, 久保彰則, 得地祐匡, 北潟谷隆, 山田錬, 重沢拓, 荘拓也, 須田剛生, 森川賢一
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] B型肝炎ウイルス宿主制限因子の回復を目指した創薬研究2021
- Author(s)
  森川賢一, 山田錬, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 肝炎ウイルス複製・病原性と関連する宿主因子のプロテオーム解析2021
- Author(s)
  森川賢一, 久保彰則, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 脂質異常症を合併する非アルコール性脂肪性肝疾患患者に対するペマフィブラート投与効果の検討2021
- Author(s)
  久保彰則, 森川賢一, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 腸内細菌叢を標的としたNASH治療戦略の検討2021
- Author(s)
  山田錬, 森川賢一, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] フォンタン術後肝合併症の現状と5年経過からみえてくること2021
- Author(s)
  荘拓也, 森川賢一, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] 肝疾患患者における筋肉量の経時変化の評価はBIA法に比べCT画像を用いた方法が有用である2021
- Author(s)
  大原正嗣, 須田剛生, 重沢拓, 鈴木和治, 中村晃久, 川岸直樹, 中井正人, 荘拓也,小川浩司, 森川賢一, 坂本直哉
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] ストレス応答よりみえてくるB型およびC型肝炎ウイルスの戦略2020
- Author(s)
  森川賢一, 須田剛生, 坂本直哉.
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K08371
[Presentation] Long-term effect of nucleos(t)ide analogs on hepatitis B surface antigen in chronic hepatits B patients.2019
- Author(s)
  1.Morikawa K, Umemura M, Ogawa K, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Kawagishi N, Shimazaki T, Kimura M, Izumi T, Nakai M, Sho T, Suda G, Natsuizaka M, Ono K, Murata K, Sugiyama M, Mizokami M, Sakamoto N.
- Organizer
  The European Association for the Study of the Liver (EASL) International Liver Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] B型慢性肝炎の核酸アナログ治療におけるインターフェロンλ3の役割の検討.2019
- Author(s)
  森川賢一, 小川浩司, 坂本直哉.
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] 羊膜由来間葉系幹細胞の消化器疾患への治療応用2018
- Author(s)
  大西俊介，山本幸司，坂本直哉
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05282
[Presentation] Risk assessment of hepatocellular carcinoma in chronic liver disease patients with a combination of liver stiffness measurement and controlled attenuation parameter by FibroScan.2018
- Author(s)
  Morikawa K, Izumi T, Sho T, Suzuki K, Nakamura A, Ohara M, Kawagishi N, Umemura M, Nakai M, Suda G, Ogawa K, Kudo Y, Nishida M, Baba M, Furuya K, Sakamoto N.
- Organizer
  The European Association for the Study of the Liver (EASL) International Liver Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] B型肝炎ウイルス発現培養細胞のプロテオメタボロミクス解析.2018
- Author(s)
  森川賢一, 梅村真知子, 坂本直哉.
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] B型肝性肝炎における核酸アナログ長期治療によるHBs抗原減少効果の検討.2018
- Author(s)
  梅村真知子, 森川賢一,坂本直哉.
- Organizer
  第42回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Changes in liver steatosis and lipid metabolism accompanied by successful interferon-free DAAs therapy in HCV infected patients; a comprehensive analysis.2018
- Author(s)
  Kawagishi N, Suda G, Morikawa K, Ogawa K, Sakamoto N.
- Organizer
  The European Association for the Study of the Liver (EASL) International Liver Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Clinical phase 1b study results for safety, pharmacokinetics and efficacy of ND-L02-s0201, a novel targeted lipid nanoparticle delivering HSP47 SIRNA for the treatment of Japanese patients with advanced liver fibrosis.2018
- Author(s)
  Sakamoto N, Ogawa K, Morikawa K, Suda G, Sho T, Nakai M, Suzuki H, Yamagata N, Tanaka Y, Ying W, Tamura Y, Niitsu Y, Maruyama K.
- Organizer
  he European Association for the Study of the Liver (EASL) International Liver Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Hepatitis B virus X protein impairs a host restriction factor via interaction with DDB1 pangenotypically.2017
- Author(s)
  Morikawa K, Sakamoto N.
- Organizer
  The 2017 International HBV Meeting. (Washington DC, USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Hepatitis B virus infected cell slows down its cell cycle and proliferation by viral protein and replication.2017
- Author(s)
  Morikawa K, Shimazaki T, Izumi T, Umemura M, Nakai M, Suda G, Sakamoto N.
- Organizer
  The European Association for the Study of the Liver (EASL) International Liver Congress. (Amsterdam, Netherlands)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] 培養細胞を用いたB型肝炎ウイルスによる宿主免疫機構の撹乱の解析.2017
- Author(s)
  森川賢一, 梅村真知子, 坂本直哉.
- Organizer
  第53回日本肝臓学会総会. (広島県広島市）
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Prevalence and risk factors of hepatitis B virus reactivation in interferon-free direct-acting antiviral therapies for hepatitis C.2017
- Author(s)
  Kawagishi N, Suda G, Onozawa M, Kimura M, Maehara O, Ohara M, Izumi T, Umemura M, Ito J, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N.
- Organizer
  The European Association for the Study of the Liver (EASL) International Liver Congress. (Amsterdam, Netherlands)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Influence of hepatitis B virus genotypes on innate immune response by impairing Mitochondrial Antiviral Signaling Protein.2017
- Author(s)
  Umemura M, Morikawa K, Ando S, Takeda R, Izumi T, Shimazaki T, Kawagishi N, Ohara M, Ito J, Nakai M, Sho T, Suda G, Ogawa K, Sakamoto N.
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference. (Nagasaki, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Hepatitis B virus X protein modulates host restriction factor via interaction with DDB1.2017
- Author(s)
  Izumi T, Morikawa K, Ando S, Takeda R, Umemura M, Shimazaki T, Kawagishi N, Ohara M, Ito J, Nakai M, Sho T, Suda G, Ogawa K, Sakamoto N.
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference. (Nagasaki, Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09400
[Presentation] Molecular Pathogenesis for HCC Development: HSF1 Potential Molecular Target for HCC Therapies2016
- Author(s)
  Chuma M, Sakamoto N, Yokoo H, Kamiyama T, Taketomi A, Maeda S.
- Organizer
  The 25th Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Tokyo
- Year and Date
  2016-02-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460982
[Presentation] 肝硬変患者に対するカルニチン製剤の有用性の検討2015
- Author(s)
  小川浩司,梅村真知子,出水孝章,伊藤淳,常松聖司,佐藤史幸,中井正人,荘拓也,須田剛生,森川賢一,坂本直哉.
- Organizer
  第117回日本消化器病学会北海道支部例会
- Place of Presentation
  札幌コンベンションセンター（北海道　札幌市）
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-15K08980
[Presentation] Analysis of First and Second Generation Protease Inhibitor Combination Therapy in Patients with Chronic Hepatitis C Virus Infection2014
- Author(s)
  須田剛生　永坂敦坂本直哉
- Organizer
  日本消化器病関連学会週間
- Place of Presentation
  神戸国際展示場　（兵庫県　神戸）
- Year and Date
  2014-10-23
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] プロテアーゼ阻害剤併用療法の治療予測因子・薬剤耐性ウイルスの検討2014
- Author(s)
  須田剛生　中馬誠坂本直哉
- Organizer
  消化器病学会総会
- Place of Presentation
  東京国際フォーラム (東京都　千代田区）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] C型慢性肝炎に対するDAA療法の治療予測因子・薬剤耐性ウイルスの検討2014
- Author(s)
  須田剛生　中馬誠坂本直哉
- Organizer
  肝臓病学会総会
- Place of Presentation
  ホテルニューオータニ　（東京都　千代田区)
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] DAA併用療法におけるDAA耐性ウイルス/治療予測因子の検討2014
- Author(s)
  須田剛生　古家乾　坂本直哉
- Organizer
  肝臓病学会東部会
- Place of Presentation
  京王プラザホテル　（東京　新宿）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] Serum granulysin levels as a predictor of serious telaprevir-induced dermatological reaction2014
- Author(s)
  Goki Suda1 ,Yoko Tsukuda1, Seiji Tsunematsu1, Fumiyuki Satou1, Katsumi Terasita1, Takuya Sho 1, Masato Nakai1, Mitsuteru Natsuizka1, Makoto Chuma 1, Naoya Sakamoto
- Organizer
  65th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston (USA)
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] 肝細胞癌の早期再発予測に関する血清バイオマーカー2014
- Author(s)
  中馬　誠、坂本　直哉、神山　俊哉
- Organizer
  第50回肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-26460982
[Presentation] Serum granulysin level is correlated with severity of telaprevir induced dermatological adverse reactions and could be a useful predictor2014
- Author(s)
  Goki Suda , Yoshiya Yamamoto, Astusi Nagasaka, Ken Furuya, Yoko Tsukuda, Seiji Tsunematsu, Fumiyuki Satou, Katsumi Terasita, Keita Horimoto, Takuya Sh Masato Nakai, Mitsuteru Natsuizka, Makoto Chuma , Naoya Sakamoto
- Organizer
  Asian Pacific Association for The Study of the Liver
- Place of Presentation
  Brisbane Convention & Exhibition Centre（Brisbene）, Australia
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] Substitution of amino acid 70/91 in the hepatitis C virus core region affects infectious virus production and cell surface expression of MHC class I.2013
- Author(s)
  Tasaka-Fujita M, Sugiyama N, Kang W, Murayama A, Asahina Y, Sakamoto N, Wakita T, Shin EC, Kato T.
- Organizer
  The 64th Annual Meeting of the American Association for the Study of Liver Disease (AASLD The Liver Meeting 2013)
- Place of Presentation
  Washington DC(USA)
- Data Source
  KAKENHI-PROJECT-24590960
[Presentation] Wnt5a-CaMK2経路による肝幹/前駆細胞の胆管分化の調節機構2013
- Author(s)
  柿沼晴、幾世橋佳、山中秀人、紙谷聡英、新田沙由梨、藤木純子、吉野耕平、中川美奈、東正新、坂本直哉、朝比奈靖浩、中内啓光、渡辺守
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京（京王プラザホテル）
- Data Source
  KAKENHI-PROJECT-24590959
[Presentation] Telaprevir/Peg-IFN/RBV3剤併用療法の治療効果および副作用予測因子の解析2013
- Author(s)
  須田剛生　中馬誠　坂本直哉
- Organizer
  日本消化器病関連学会週間
- Place of Presentation
  グランドプリンス高輪ホテル（東京）
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] Wnt5a-CaMK2経路による肝幹/前駆細胞の分化調節機構2013
- Author(s)
  柿沼晴、幾世橋佳、紙谷聡英、新田沙由梨、東正新、中川美奈、朝比奈靖浩、坂本直哉、中内啓光、渡辺守
- Organizer
  JDDW 2013 第17回日本肝臓学会大会
- Place of Presentation
  東京（グランドプリンスホテル新高輪）
- Data Source
  KAKENHI-PROJECT-24590959
[Presentation] Establishment of Interferon resistant genotype 2b/JFH-1 chimeric Hepatitis C virus cell culture system2013
- Author(s)
  Goki Suda, Yoko Tsukuda, Mitsuteru Natsuizaka, Makoto Chuma, Naoya Sakamoto
- Organizer
  64th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Walter E. Washington Convention Center　（Wachington DC）, USA
- Data Source
  KAKENHI-PROJECT-25860513
[Presentation] 宿主遺伝子情報に基づいたC型慢性肝炎治療の効果・安全性の最適化（シンポジウム6ゲノムワイド検索（GWAS）と消化器疾患）2012
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-24659359
[Presentation] Treatment and outcomes for elderly patientswith hepatocellular caricinoma2012
- Author(s)
  Azuma S, Sakamoto N, Sakurai Y, Nakagawa M, Kakinuma S, Watanabe M
- Organizer
  22nd Conference of the Asian Pacific Association for the Study of the Liver, Feb-18-2012, Taipei, Taiwan
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2012-02-18
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] HCV-NS4B blocks the RIG-I mediated IFN pathway through targeting of STING2012
- Author(s)
  Sayuri Nitta, Naoya Sakamoto, Mina Nakagawa, Sei Kakinuma, Kako Mishima, Akiko Kusano-Kitazume, Kei Kiyohashi, Miyako Murakawa, Kohei Yoshino, Megumi Tasaka-Fujita, Yasuhiro Asahina, Mamoru Watanabe
- Organizer
  19^<th> International Symposium of Hepatitis C Virus and Related Viruses
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] 宿主遺伝子情報に基づいたC型慢性肝炎治療の効果・安全性の最適化(シンポジウム6)2012
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-24390185
[Presentation] Let-7b is a novel regulator of hepatitis C virus replication. J Hepatol 2011; in submission.. 19th. International Meeting on Hepatitis C Virus &Related Viruses.2012
- Author(s)
  Yeh YJ, Tseng CP, Sakamoto N,et al.
- Organizer
  19th. International Meeting on Hepatitis C Virus & Related Viruses.
- Place of Presentation
  Palazzo del Cinema（イタリア、ベニス）
- Data Source
  KAKENHI-PROJECT-24659359
[Presentation] HCV-NS4B protein binds STINGand blocks the RIG-I mediated IFN pathway2012
- Author(s)
  Sayuri Nitta, Naoya Sakamoto, Mina Nakagawa, Sei Kakinuma, Akiko Kusano Kitazume, Miyako Murakawa, Megumi Tasaka-Fujita, Yasuhiro Asahina, Mamoru Watanabe
- Organizer
  10th single topic conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCVNS4B蛋白はSTINGを介しRIG-I誘導性 Interferon産生応答を抑制する2012
- Author(s)
  新田沙由梨、坂本直哉、吉野耕平、村川美也子、北詰晶子、幾世橋佳、東正新、柿沼晴、中川美奈、朝比奈靖浩、渡辺守
- Organizer
  第48回肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCV NS4B蛋白によるRIG-I誘導性Interferon発現経路の抑制機構についての解析2012
- Author(s)
  新田沙由梨、坂本直哉、吉野耕平、村川美也子、北詰晶子、幾世橋佳、東正新、柿沼晴、中川美奈、朝比奈靖浩、渡辺守
- Organizer
  JDDW2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] IFN不応例における宿主自然免疫応答とHCV逃避機構2012
- Author(s)
  新田沙由梨,朝比奈靖浩,坂本直哉,村川美也子,北詰晶子,幾世橋佳,東正新,柿沼晴,中川美奈,渡辺守
- Organizer
  第77回日本インターフェロン・サイトカイン学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] 肝線維形成過程におけるMatrix Metalloproteinase-2の機能的意義(シンポジウム8)2012
- Author(s)
  柿沼晴、坂本直哉、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-24390185
[Presentation] Treatment and outcomes for elderly patients with hepatocellular caricinoma2012
- Author(s)
  Azuma S, Sakamoto N, Kakinuma S, Watanabe M, et al
- Organizer
  The 22nd Conference of the Asian Pacific Association for the Study of the Liver
- Place of Presentation
  Taipei,台湾
- Year and Date
  2012-02-17
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] IL-6を介したC型慢性肝炎のインターフェロン治療抵抗性機構(シンポジウム3)2012
- Author(s)
  坂本直哉、中川美奈、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-24390185
[Presentation] Imparied IL28B gene induction and poor IL28B promoter activity influenced by the IL28B minor allele are closely associated with a null response to interferon in chronic hepatitis C patients.2012
- Author(s)
  Asahina Y, Sakamoto N, Azuma S, Watanabe M et al
- Organizer
  AASLD The Liver Meeting 2012
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] IL-6を介したC型慢性肝炎のインターフェロン治療抵抗性機構（シンポジウム3 ）2012
- Author(s)
  坂本直哉、中川美奈、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-24659359
[Presentation] Antiviral effects and action mechanisms of novel N-(morpholine-4-carbonyloxy) amidine compaunds against hepatitis C virus.2012
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Azuma S, Asahina Y, Watanabe M et al
- Organizer
  AASLD The Liver Meeting 2012
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Let-7b is a novel regulator of hepatitis C virus replication.2012
- Author(s)
  Yeh YJ, Tseng CP, Sakamoto, N, et al.
- Organizer
  19th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Palazzio del Chinema (Venice, Italy)
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PROJECT-24390185
[Presentation] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Sakamoto N, Nakagawa M, Watanabe M, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Antiviral effect of a novel interferon-inducible protein, IFI-27, against hepatitis C virus replication2011
- Author(s)
  Itsuil Y, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic henatitis C patients2011
- Author(s)
  Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV-NS4B targets STING and abrogates RIG-I-mediated type-I interferon- dependent innate immune response2011
- Author(s)
  Nitta S, Sakamoto N, Watanabe M, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] 蛍光蛋白発現HCV培養系を用いたHigh-content screening assayの樹立及びHCVエントリー阻害剤探索への応用2011
- Author(s)
  北詰晶子、坂本直哉、奥野友紀子、筬島裕子、中川美奈、柿沼晴、植山真由美、小野塚泉、船岡祐介、渡辺貴子、幾世橋佳、新田沙由梨、村川美也子、萩原正敏、渡辺守
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京(一般口演, O-164)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] IL28B and ITPA gene variants correlate with treatment efficacy in pegylated-interferon plus ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Matsuura K, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Mutations in the interferon sensitivity determining region of HCV, age and total ribavirin dose is an independent predictor of relapse among early virological responders to peg-interferon plus ribavirin therapy2011
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic hepatitis C patients2011
- Author(s)
  Sakamoto N, Azuma S, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCV-NS4B蛋白とRIG-I惹起性IFN産生シグナル関連蛋白との分子間相互作用の解析2011
- Author(s)
  新田沙由梨、坂本直哉、藤田めぐみ、柿沼晴、村川美也子、北詰晶子、幾世橋佳、船岡祐介、渡辺貴子、植山真由美、小野塚泉、櫻井幸、中川美奈、東正新、渡辺守
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2011-06-02
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Yoshida T, Sakamoto N, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] IL28B and ITPA gene variants correlate with treatment efficacy in pegylated-interferon plus ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Matsuura K, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates fo rsmall molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Yamamoto M, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyohashi K, Nitta S, Murakawa M, Hagiwara M, Watanabe M
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA.(Poster# 383)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV-NS4B targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immune response2011
- Author(s)
  Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Prediction model of ribavirin-induced anemia incorporating ITPA genotype could identify chronic hepatitis C patients at high risk of relapse among virological responders to pegylated-interferon and ribavirin2011
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Kamiya A, Sakamoto N, Nakauchi H, Watanabe M
- Organizer
  62nd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] 肝線維化プロセスにおけるMatrixMetalloproteinase-2の機能2011
- Author(s)
  柿沼晴、紙谷聡英、小野塚泉、東正新、坂本直哉、中内啓光、渡辺守
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic hepatitis C patients2011
- Author(s)
  Sakamoto N, Tanaka Y, Nakagawa M, Yatsuhashi H, Nishiguchi S, Enomoto N, Azuma S, Nishimura-Sakurai Y, Kakinuma S, Nishida N, Tokunaga K, Mizokami M, Watanabe M
- Organizer
  62 nd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA. USA
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] Antiviral effect of a novel interferon-inducible protein, IFI-27, against hepatitis C virus replication2011
- Author(s)
  Itsuil Y, Sakamoto N, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Prediction model of ribavirin-induced anemia incorporating ITPA genotype could identify chronic hepatitis C patients at high risk of relapse among virological responders to pegylated-interferon and ribavirin2011
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic hepatitis C patients2011
- Author(s)
  Sakamoto N, Azuma S, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Yoshida T, Sakamoto N, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV-NS4B蛋白とIFN発現シグナル分子との分子間相互作用の解析2011
- Author(s)
  新田沙由梨、坂本直哉、藤田めぐみ、北詰晶子、幾世橋佳、船岡祐介、渡辺貴子、植山真由美、小野塚泉、東正新、中川美奈、柿沼晴、渡辺守
- Organizer
  第48回日本消化器免疫学会
- Place of Presentation
  金沢
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Antiviral effect of a novel interferon-inducible protein, IFI-27, against hepatitis C virus replication2011
- Author(s)
  Itsuil Y, Sakamoto N, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Loww of Wnt5A promotes biliary differentiation of murine hepatic stem/progenitor cells2011
- Author(s)
  Kiyohashi K, Sakamoto N, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates for small molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Okuno Y, Yamamoto M, Sekine-Osajima Y, Nakagawa M, Kakinuma S, Kiyohashi K, Nitta S, Murakawa M, Hagiwara M, Watanabe M
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA.(Poster# 383)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Yoshiaki Yamagishi, Takeshi Yoshida, Masuo Kondoh, Hiroyuki Mizuguchi, Naoya Sakamoto, Akihiro Watari, Kiyohito Yagi
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington, DC
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Loww of Wnt5A promotes biliary differentiation of murine hepatic stem/progenitor cells2011
- Author(s)
  Kiyohashi K, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2011
- Author(s)
  Suda G, Sakamoto N, Itsui Y, Nakagawa M, Tasaka-Fujita M, Funaoka Y, Watanabe T, Nitta S, Kiyohashi K, Azuma S, Kakinuma S, Tsuchiya K, Imamura M, Hiraga N, Chayama K, Watanabe M
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates for small molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Nakagawa M, Kakinuma S, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Yamagishi Y, Sakamoto N, et al.
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2011
- Author(s)
  Suda G, Sakamoto N, Azuma S, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Cell based high-throughput screeningによる新規抗ウイルス小分子の同定及びその作用機構の解析2011
- Author(s)
  北詰晶子、坂本直哉、奥野友紀子、筬島裕子、中川美奈、柿沼晴、植山真由美、小野塚泉、船岡祐介、渡辺貴子、幾世橋佳、新田沙由梨、村川美也子、萩原正敏、渡辺守
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  東京(一般口演, O-156)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2011
- Author(s)
  Suda G, Sakamoto N, Nakagawa M, Azuma S, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Prediction model of ribavirin-induced anemia incorporating ITPA genotype could identify chronic hepatitis C patients at high risk of relapse among virological responders to pegylated-interferon and ribavirin2011
- Author(s)
  Kurosaki M, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Yamagishi Y, Sakamoto N, et al.
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] IL28B and ITPA gene variants correlate with treatment efficacy in pegylated-interferon plus ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Matsuura K, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] HCV-NS4B targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immune response2011
- Author(s)
  Nitta S, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al
- Organizer
  62nd Annual meeting of the American Association of the Study of Liver Disease
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Yamagishi Y, Sakamoto N, et al
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Sakamoto N, Watanabe M, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] MMP-2 and MMP-14 derived from donor cells enhance therapeutic efficacy of liver cell transplantation in mice2011
- Author(s)
  Kakinuma S, Sakamoto N, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Mutations in the interferon sensitivity determining region of HCV, age and total ribavirin dose is an independent predictor of relapse among early virological responders to peg-interferon plus ribavirin therapy2011
- Author(s)
  Kurosaki M, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Sakamoto N, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] ITPA gene variant protects against treatment-induced anemia and improves viral clearance by pegylated interferon-alfa and ribavirin therapy in chronic hepatitis C patients2011
- Author(s)
  Sakamoto N, Nakagawa M, Kakinuma S, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] IL-6-mediated intersubgenotypic variation of interferon sensitivity in hepatitis C virus genotype 2a/2b chimeric clones2011
- Author(s)
  Suda G, Sakamoto N, Nakagawa M, Kakinuma S, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCV-NS4B targets STING anda brogates RIG-I-mediated type-Iinterferon-dependent innate immune response2011
- Author(s)
  Sayuri Nitta, Naoya Sakamoto, Megumi Tasaka-Fujita, Kei Kiyohashi, Akiko Kusano-Kitazume, Miyako Murakawa, Kouhei Yoshino, Kako Mishima, SeiKakinuma, Mina Nakagawa, Mamoru Watanabe
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle, WA
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] IL28B and ITPA gene variants correlate with treatment effcacy in pegylated-interferon plus ribavirin therapy for chronic hepatitis C2011
- Author(s)
  Matsuura K, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] EYFP発現HCV培養系を用いたHigh-content screening assayによるウイルス侵入阻害剤の同定.(ポスターP26)2011
- Author(s)
  北詰晶子、坂本直哉、奥野友紀子、中川美奈、柿沼晴、山本満千、幾世橋佳、新田沙由梨、村川美也子、萩原正敏、渡辺守
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCV-NS4B targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immune response2011
- Author(s)
  Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-KitazumeA, KiyohashiK, Murakawa M, Yoshino K, Tasaka-Fujita M, Watanabe M
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates for small molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Mutations in the interferon sensitivity determining region of HCV, age and total ribavirin dose is an independent predictor of relapse among early virological responders to peg-interferon plus ribavirin therapy2011
- Author(s)
  Kurosaki M, Sakamoto N, Nakagawa M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Takeshi Yoshida, Fumi Satoh, Watari Akihiro, Masuo Kondoh, Hiroyuk iMizuguchi, Naoya Sakamoto, Kiyohito Yagi
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle, WA
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV-NS4B targets STING and abrogates RIG-I-mediated type-I interferon-dependent innate immune response2011
- Author(s)
  Nitta S, Sakamoto N, Tasaka-Fujita M, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Antiviral effect of a novel interferon-inducible protein, IFI-27, against hepatitis C virus replication2011
- Author(s)
  Itsuil Y, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Yoshida T, Sakamoto N, et al
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] 高齢者肝細胞癌患者に対する治療方法とその成績2011
- Author(s)
  東正新、坂本直哉、桜井幸、吉野耕平、幾世橋佳、新田沙由梨、北詰晶子、村川美也子、中川美奈、柿沼晴、渡辺守
- Organizer
  JDDW 2011(第15回日本肝臓学会大会)
- Place of Presentation
  福岡
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] Loww of Wnt5A promotes biliary differentiation of murine hepatic stem/progenitor cells2011
- Author(s)
  Kiyohashi K, Sakamoto N, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Loww of Wnt5A promotes biliary differentiation of murine hepatic stem/progenitor cells2011
- Author(s)
  Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nakauchi H, Watanabe M
- Organizer
  62 nd Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA. USA
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates for small molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Watanabe M, et al
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Prediction model of ribavirin-induced anemia incorporating ITPA genotype could identify chronic hepatitis C patients at high risk of relapse among virological responders to pegylated-interferon and ribavirin2011
- Author(s)
  Kurosaki M, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Naoya Sakamoto, Yusuke Funaoka, Goki Suda, Mina Nakagawa, Sei Kakinuma, Mamoru Watanabe
- Organizer
  18th. International Meeting on Hepatitis C Virus & RelatedViruses
- Place of Presentation
  Seattle, WA
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Development of RNA pol-driven adenovirus vector expressing hepatitis C virus replicon2011
- Author(s)
  Yamagishi Y, Sakamoto N, et al
- Organizer
  Experimental Biology 2011
- Place of Presentation
  Washington
- Year and Date
  2011-04-13
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Analysis of interferon signaling by infectious hepatitis C virus clones with substitutions of core amino acids 70 and 912011
- Author(s)
  Sakamoto N, Nakagawa M, Kakinuma S, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Loww of Wnt5A promotes biliary differentiation of murine hepatic stem/progenitor cells2011
- Author(s)
  Kiyohashi K, Kakinuma S, Sakamoto N, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] A high-content screening assay using infectious fluorescence-tagged hepatitis C virus reveals candidates for small molecule inhibitors of viral entry2011
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Development of an RNA polymerase I-driven adenoviral vector and its application in an HCV replication assay2011
- Author(s)
  Yoshida T, Sakamoto N, et al.
- Organizer
  18th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Seattle
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Mutations in the interferon sensitivity determining region of HCV, age and total ribavirin dose is an independent predictor of relapse among early virological responders to peg-interferon plus ribavirin therapy2011
- Author(s)
  Kurosaki M, Sakamoto N, Kakinuma S, Nakagawa M, et al.
- Organizer
  62th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] RFA治療におけるreal-time 3D超音波の有用性2010
- Author(s)
  墓正新, 坂本杢直哉, 渡辺守, 他
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] 細胞障害性HCV-JFH1subcloneの細胞培養系および感染動物モデルにおける機能解析2010
- Author(s)
  三島果子、坂本直哉、筬島裕子、中川美奈、柿沼晴、東正新、脇田隆字、今村道雄、茶山一彰、渡辺守
- Organizer
  JDDW2010
- Place of Presentation
  横浜(ポスター)
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCV増殖を制御するインターフェロン誘導性蛋白GBP-1が介する分子免疫機構(シンポジウム)2010
- Author(s)
  井津井康浩、坂本直哉、渡辺守
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Genotype 2b HCV感染培養系におけるIL6を介したInterferOn抵抗性発現機構の解析(ワークショップ)2010
- Author(s)
  須田剛生、坂本直哉、渡辺守
- Organizer
  JDDW2010(第14回日本肝臓学会大会)
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] The inhibitory effect of triterpenoid compound with or without interferonαon Hepatitis C virus infection2010
- Author(s)
  Takako Watanabe, Naoya Sakamoto, Mina Nakagawa, Yasuhiro Itsui, Yuki Nishimura-Sakurai, Megumi Tasaka-Fujita, Yuko Sekine-Osajima, and Mamoru Watanabe
- Organizer
  17th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV増殖を制御するインターフェロン誘導性蛋白GBP-1が介する分子免疫機構2010
- Author(s)
  井津井康浩、坂本直哉、渡辺守
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟(シンポジウム)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCVレプリコン系を用いた抗ウイルス小分子の大規模スクリーニング.(ポスター)2010
- Author(s)
  北詰晶子、坂本直哉、筬島裕子、中川美奈、東正新、柿沼晴、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] ウイルスおよび宿主遺伝子情報に基づくC型慢性肝炎の治療戦略(パネルディスカッション)2010
- Author(s)
  中川美奈、柿沼晴、坂本直哉
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] 蛍光タグ付加HCV培養系を用いたウイルスライフサイクルの解析.(一般口演)2010
- Author(s)
  山本満千、坂本直哉、中川美奈、柿沼晴、東正新、加藤孝宣、脇田隆字、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Analysis of cell surface molecules on transplantable hepatic progenitor cells in mouse fetal neonatal livers2010
- Author(s)
  Kakinuma S, Kamiya A, Sakamoto N, Watanabe M, Nakauchi H
- Organizer
  1st JSGE International Topic Conference
- Place of Presentation
  Kamakura, JAPAN
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] Genotype 2b HCV感染培養系におけるIL-6を介したlnterferon抵抗性発現機構の解析2010
- Author(s)
  須田剛生、坂本直哉、渡辺守
- Organizer
  JDDW2010(第14回日本肝臓学会大会)
- Place of Presentation
  横浜(ワークショップ)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] ウイルス遺伝子および宿主IL28B遺伝子情報を統合したC型慢性肝炎治療のオーダーメイド化.(シンポジウム)2010
- Author(s)
  坂本直哉、中川美奈、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] 蛍光タグ付加HCV培養系を用いたウイルスライフサイクルの解析2010
- Author(s)
  山本満千、坂本直哉、中川美奈、柿沼晴、東正新、加藤孝宣、脇田隆字、渡辺守
- Organizer
  JDDW2010
- Place of Presentation
  横浜(ポスター)
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCV増殖を制御する宿主インターフェロン誘導遣伝子GBP-1が介する分子機構(ワークショップ)2010
- Author(s)
  井津井康浩、坂本直哉、渡辺守
- Organizer
  JDDW20lO(第14回日本肝臓学会大会)
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] C型慢性肝炎のインターフェロン治療効果におけるインターロイキン-6(IL-6)の関与2010
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  JDDW2010(第14回日本肝臓学会大会)
- Place of Presentation
  横浜(パネルディスカッション)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] ウイルスおよび宿主遺伝子情報に基づくC型慢性肝炎の治療戦略2010
- Author(s)
  中川美奈、柿沼晴、坂本直哉
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京(パネルディスカッション)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] ウイルス遺伝子および宿主IL28B遺伝子情報を統合したC型慢性肝炎治療のオーダーメイド化2010
- Author(s)
  坂本直哉、中川美奈、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形(シンポジウム)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Identification of Novel Small Molecules Inhibitors of Hepatitis C Virus Replication Using a Cell-Based High-Throughput Screen2010
- Author(s)
  Akiko Kusano-Kitazume, Naoya Sakamoto, Yuko Sekine-Osajima, Seishin Azuma, Mina Nakagawa, Sei Kakinuma, Yuki Nishimura-Sakurai, Yukiko Okuno, Masatoshi Hagiwara, and Mamoru Watanabe
- Organizer
  17th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] タイトル:IL28B遺伝子多型と治療抵抗性ウイルス変異からみたC型慢性肝炎の治療抵抗メカニズムの解析2010
- Author(s)
  中川美奈、柿沼晴、坂本直哉
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京(ワークショップ)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] HCV増殖を制御する宿主インターフェロン誘導遺伝子GBP-1が介する分子機構2010
- Author(s)
  井津井康浩、坂本直哉、渡辺守
- Organizer
  JDDW2010(第14回日本肝臓学会大会)
- Place of Presentation
  横浜(ワークショップ)
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] Identification of Novel Small Molecules Inhibitors of Hepatitis C Virus Replication Using a Cell-Based High-Throughput Screen.2010
- Author(s)
  Akiko Kusano-Kitazume, Naoya Sakamoto, Yuko Sekine-Osajima, Seishin Azuma, Mina Nakagawa, Sei Kakinuma, Yuki Nishimura-Sakurai, Yukiko Okuno, Masatoshi Hagiwara, and Mamoru Watanabe
- Organizer
  17th International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] SR蛋白リン酸化酵素(SRPK)阻害剤によるHCV増殖抑制効果の解析(ワークシヨップ)2010
- Author(s)
  唐鎌優子、坂本直哉、小野木博、井津井康浩、中川美奈、柿沼晴、東正新、萩原正敏、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV genotype 2a/2b感染クローンを用いたInterferon抵抗性発現機構の解析2010
- Author(s)
  坂本直哉、須田剛生、渡辺守
- Organizer
  第47回日本消化器免疫学会
- Place of Presentation
  大津(シンポジウム)
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] タイトル:IL28B遺伝子多型と治療抵抗性ウイルス変異からみたC型慢性肝炎の治療抵抗メカニズムの解析(ワークショップ)2010
- Author(s)
  中川美奈、柿沼晴、坂本直哉
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] HCV genotype 2a/2b感染クローンを用いたInterferon抵抗性発現機構の解析(シンポジウム)2010
- Author(s)
  坂本直哉、須田剛生、渡辺守
- Organizer
  第47回日本消化器免疫学会
- Place of Presentation
  大津
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] SR蛋白リン酸化酵素(SRPK)阻害剤によるHCV増殖抑制効果の解析2010
- Author(s)
  唐鎌優子、坂本直哉、小野木博、井津井康浩、中川美奈、柿沼晴、東正新、萩原正敏、渡辺守
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形(ワークショップ)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22659145
[Presentation] C型慢性肝炎のインターフェロン治療効果におけるインターロイキン-6(IL-6)の関与(パネルディスカッション)2010
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  JDDW2010(第14回日本肝臓学会大会)
- Place of Presentation
  横浜
- Year and Date
  2010-10-14
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] 細胞障害性HCV-JFH1における遺伝子変異の機能解析とin vivo感染動態の検討2010
- Author(s)
  三島果子、坂本直哉、筬島裕子、中川美奈、柿沼晴、陳正新、脇田隆字、今村道雄、茶山一彰、渡辺守
- Organizer
  (一般口演)第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] 肝臓細胞移植におけるドナー由来MatrixMetalloproteinaseの関与2010
- Author(s)
  柿沼晴、紙谷聡英、坂本直哉、渡辺守、中内啓光
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] Establishment and genetic analyses of cytopathogenic HCV-JFH1 mutants by plaque-forming assay2009
- Author(s)
  Mishima K, Sakamoto N, Sekine-Osajima Y, Nakagawa M, Tasaka M, Nishimura-Sakurai Y, Itsui Y, Wakita T, Watanabe M
- Place of Presentation
  Nice
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCV増殖を制御するInterferon誘導蛋白とHCV非構造蛋白の相互作用の解析2009
- Author(s)
  井津井康浩、坂本直哉、中川美奈、筬島裕子、田坂めぐみ、櫻井幸、須田剛生、三島果子、山本満千、植山真由美、渡辺貴子、船岡祐介、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCV複製増殖に関連する糖脂質代謝ネットワークの網羅的解析2009
- Author(s)
  櫻井幸、坂本直哉、中川美奈、井津井康浩、田坂めぐみ、小貫優子、須田剛生、三島果子、山本満千、植山真由美、船岡祐介、渡辺貴子、陳正新、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Establishment and genetic analyses of cytopathogenic HCV-JFH1 mutants by plaque-forming assay2009
- Author(s)
  Kako Mishima, Naoya Sakamoto, Yuko Sekine-Osajima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Takaji Wakita, and Mamoru Watanabe
- Organizer
  16th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Nice, France
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] Establishment and genetic analyses of cytopathogenic HCV-JFH1 mutants by plaque-forming assay.2009
- Author(s)
  Mishima K, Sakamoto N, et al
- Organizer
  16th.International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Nice
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] 細胞傷害性HCV-JFH1subcloneの単離と機能解析.(ワークショップ3)2009
- Author(s)
  三島果子坂本直哉中川美奈井津井康浩筬島裕子田坂めぐみ櫻井幸須田剛生山本満千植山真由美渡辺貴子船岡祐介渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] In-vitro replication and interferon sensitivity of core aa 70 and 91 mutant HCV cell culture2009
- Author(s)
  Yusuke Funaoka, Naoya Sakamoto, Goki Suda, Yasuhiro Itsui, Mina Nakagawa, Kako Mishima, Yuko Karakama, Machi Yamamoto, Cheng-Hsin Chen-Azuma, Sei Kakinuma and Mamoru Watanabe
- Organizer
  60th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Antiviral effects of interferon-induced proteins GBP-1 and its interactions with hepatitis C virus NS5B protein.2009
- Author(s)
  Itsui Y, Sakamoto N, et al
- Organizer
  60th.Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Establishment and genetic analyses of cytopathogenic HCV-JFH1 mutants by plaque-forming assay2009
- Author(s)
  Kako Mishima, Naoya Sakamoto, Yuko Sekine-Osajima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Takaji Wakita, and Mamoru Watanabe
- Organizer
  16th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Nice, France
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] In-vitro and in-vivo Characterization of a new genotype 2b HCV clone and 2b/JFH1 intergenotypic chimera and analyses of the factor that regulate interferon sensitivity.2009
- Author(s)
  Suda G, Sakamoto N, et al
- Organizer
  60th.Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] マウス胎生中期肝幹/前駆細胞を用いた細胞移植2009
- Author(s)
  柿沼晴、紙谷聡英、太田春彦、坂本直哉、渡辺守、中内啓光
- Organizer
  JDDW 2009 (第13回日本肝臓学会大会)
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20790485
[Presentation] Genotype 2b急性肝炎由来HCVクローンの構築と増殖・粒子形成能の解析2009
- Author(s)
  須田剛生、坂本直哉、中川美奈、田坂めぐみ、櫻井幸、小貫優子、山本満千、渡辺貴子、植山真由美、船岡祐介、井津井康浩、陳正新、今村道雄、茶山一彰、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Genotype 2型C型慢性肝炎のインターフェロン治療再燃例に対する再治療の試み2009
- Author(s)
  渡辺貴子、中川美奈、船岡祐介、植山真由美、三島果子、山本満千、小貫優子、須田剛生、櫻井幸、田坂めぐみ、筬島裕子、井津井康浩、陳正新、坂本直哉、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] HCVコア変異株培養系を用いたインターフェロン感受性、細胞内増殖、粒子分泌能の解析2009
- Author(s)
  船岡祐介、坂本直哉、井津井康浩、須田剛生、中川美奈、田坂めぐみ、櫻井幸、小貫優子、山本満千、渡辺貴子、植山真由美、陳正新、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] In-vitro replication and interferon sensitivity of core aa 70 and 91 mutant HCV cell culture.2009
- Author(s)
  Funaoka Y, Sakamoto N, et al
- Organizer
  60th.Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] Antiviral effects of interferon-induced proteins GBP-1 and its interactions with hepatitis C virusNS5B protein2009
- Author(s)
  Itsui Y, Sakamoto N, Nakagawa M, Osajima Y, Tasaka M, Sakurai Y, Suda G, Karakama Y, Mishima K, Yamamoto M, Watanabe T, Ueyama M, Funaoka Y, Azuma S (Chen CH), Kakinuma S, Yauchi T, Watanabe M
- Organizer
  60th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston
- Year and Date
  2009-11-02
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] マウス胎生中期肝幹/前駆細胞を用いた細胞移植2009
- Author(s)
  柿沼晴、坂本直哉、渡辺守, 他
- Organizer
  JDDW2009(第13回日本肝臓学会大会)
- Place of Presentation
  京都
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] RFA治療における4D超音波の有効性2009
- Author(s)
  東正新、坂本直哉, 他
- Organizer
  第45回日本肝癌研究会
- Place of Presentation
  福岡
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-21590833
[Presentation] 細胞障害性HCV-JFH1 subcloneの単離と機能解析2009
- Author(s)
  三島果子、坂本直哉、中川美奈、井津井康浩、筬島裕子、田坂めぐみ、櫻井幸、須田剛生、山本満千、植山真由美、渡辺貴子、船岡祐介、渡辺守
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] In-vitro and in-vivo Characterization of a new genotype 2b HCV clone and 2b/JFH1 intergenotypic chimera and analyses of the factor that regulate interferon sensitivity2009
- Author(s)
  Goki Suda, Naoya Sakamoto, Yasuhiro Itsui, Mina Nakagawa, Kako Mishima, Yuko Karakama, Machi Yamamoto, Cheng-Hsin Chen, Sei Kaki numa, KazuakiChayama, Michio Imamura and Mamoru Watanabe
- Organizer
  60th. Annual Meeting of American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21390226
[Presentation] 3cmを超える肝細胞癌に対する当科の治療方法と成績2008
- Author(s)
  陳正新、坂本直哉、井津井康浩、中川美奈、櫻井幸、須田剛生、山本満千、小貫優子、三島果子、渡辺守
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19590752
[Presentation] A novel NS5B-interacting protein modulates hepatitis C virus replication.2008
- Author(s)
  Jing-Tang Huang, Ching-Ping Tseng, Naoya Sakamoto, Shao-Chun Lu, Chuan-Mu Chen, Ju-Chien Cheng
- Organizer
  15th. International Meeting on Hepatitis C Virus & Related Viruses.
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Establishment and genetic analyses of cytopathogenic HCV-JFH1 mutants by plaque-forming assay2008
- Author(s)
  Naoya Sakamoto, Kako Mishima, YukoSekine-Osajima, Mina Nakagawa, MegumiTasaka, Yuki Nishimura-Sakurai, YasuhiroItsui, Takaji Wakita,and Mamoru Watanabe
- Organizer
  15th. International Meeting on Hepatitis C Virus & RelatedViruses
- Place of Presentation
  San Antonio, TX
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] A novel NS5B-interacting protein modulates hepatitis C virus replication2008
- Author(s)
  Jing-Tang Huang, Ching-Ping Tseng, Naoya Sakamoto, Shao-Chun Lu, Chuan-Mu Chen,Ju-Chien Cheng
- Organizer
  15th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  San Antonio, TX
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Pretreatment assessment of PEG-interferon plus ribavirin anti-HCV therapy using viral genetic profiles, NS5A-ISDR and Core mutations2008
- Author(s)
  Naoya Sakamoto, Mina Nakagawa,Cheng-Hsin Chen, Yasuhiro Itsui, Megumi Tasaka, Nobuyuki Enomoto,and Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco,CA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Establishment and genetic analyses of cytopatho genic HCV-JFH1 mutants by plaque-forming assay2008
- Author(s)
  Kako Mishima, Naoya Sakamoto, YukoSekine-Osajima, Mina Nakagawa, MegumiTasaka, Yuki Nishimura-Sakurai, YasuhiroItsui, Takaji Wakita,and Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco,CA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Establishment and genetic analyzes of cytopathogenic HCV-JFHI mutants by plaque-forming assay.2008
- Author(s)
  Naoya Sakamoto, Kako Mishima, Yuko Sekine-Osajima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Takaji Wakita, Mamoru Watanabe
- Organizer
  15th. International Meeting on Hepatitis C Virus & Related Viruses.
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Establishment and genetic analyzes of cytopathogenic HCV-JFH1 mutants by plaque-forming assay.2008
- Author(s)
  Kako Mishima, Naoya Sakamoto. Yuko Sekine-Osajima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Takaji Wakita, Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Suppression of interferon induction and response pathway by Hepatitis C virus NS4B2008
- Author(s)
  M. Tasaka, N. Sakamoto, M. Nakagawa, Y.Itsui, Y. Nishimura-Sakurai, C. Chen, Goki Suda, Kako Mishima, Machi Yamamoto,Yuko Onuki, M. Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco,CA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Pretreatment assessment of PEG-interferon plus ribavirin anti-HCV therapy using viral genetic profiles, NS5A-ISDR and Core mutations.2008
- Author(s)
  Naoya Sakamoto, Mina Nakagawa, Cheng-Hsin Chen, Yasuhiro Itsui, Megumi Tasaka, Nobuyuki Enomoto, Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] THE ISOMERASE ACTIVITY OF CYCLOPHILIN A IS CRITICAL FOR HCV REPLICATION.2008
- Author(s)
  Bobardt M., Chatterji U., Selvarajah S., Tang H., Sakamoto N., Coelmont L., Neyts J., Dumont J. -M., Vuagniaux G., Gallay P.
- Organizer
  15th. International Meeting on Hepatitis C Virus & Related Viruses.
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Suppression of interferon induction and response pathway by Hepatitis C virus NS4B.2008
- Author(s)
  M. Tasakal, N. Sakamoto, M. Nakagawa, Y. Itsui, Y. Nishimura-Sakurai, C. Chen, Goki Suda, Kako Mishima, Machi Yamamoto, Yuko Onuki, M. Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] THE ISOMERASE ACTIVITY OF CYCLOPHILIN A IS CRITICAL FOR HCV REPLICATION2008
- Author(s)
  Bobardt M., Chatterji U., Selvarajah S., TangH., Sakamoto N., Coelmont L., Neyts J.,Dumont J.-M., Vuagniaux G.and Gallay P.
- Organizer
  15th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  San Antonio, TX
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] ラジオ波熱凝固療法における第二世代超音波造影剤の有用性2007
- Author(s)
  陳正新、坂本直哉、井津井康浩、中川美奈、筬島裕子、田坂めぐみ、櫻井幸、渡辺守
- Organizer
  JDDW2007(第10回日本肝臓学会大会)
- Place of Presentation
  神戸
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19590752
[Presentation] Antiviral effects of interferon-induced proteins, GBP-1, IFI6-16 and IFI27 and their interactions with hepatitis C virus nonstructural proteins2007
- Author(s)
  Yasuhiro Itsui, Naoya Sakamoto, Mina Nakagawa, Yuko Sekine-Osajima, Megumi Tasaka,and Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA
- Year and Date
  2007-10-31
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Plaque-forming assays for hepatitis C virus and isolation of HCV-JFH1 mutants with enhanced cytopathogenicity and replication capacity2007
- Author(s)
  Naoya Sakamoto, Yuko Sekine-Osajima, Kako Mishima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, YasuhiroItsui, Takaji Wakita,and Mamoru Watanabe
- Organizer
  Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Boston, MA
- Year and Date
  2007-10-31
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] 当科における高齢肝細胞癌患者に対するラジオ波熱凝固療法の治療成績2007
- Author(s)
  陳正新、坂本直哉、渡辺守
- Organizer
  第43回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-19590752
[Presentation] Development of plaque-forming assays for hepatitis C virus and isolation of mutants with enhanced cytopathogenicity and replication capacity2007
- Author(s)
  Naoya Sakamoto, Yuko Sekine-Osajima, Kako Mishima, Mina Nakagawa, Megumi Tasaka, Yuki Nishimura-Sakurai, Yasuhiro Itsui, Takaji Wakita,and Mamoru Watanabe
- Organizer
  14th. International Meeting on Hepatitis C Virus & Related Viruses
- Place of Presentation
  Glasgow, UK
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] for the Ochanomizu Liver Conference : Clinical and virological factors that predict outcomes of interferon plus ribavirin combination therapy for HCV infection2007
- Author(s)
  Sakamoto N, Nakagawa M, Watanabe M
- Organizer
  APDW 2007 Symposium
- Place of Presentation
  Kobe, Japan
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Clinical and virological factors that predict outcomes of interferon plus ribavirin combination therapy for HCV infection.2007
- Author(s)
  Sakamoto N, Nakagawa M, Watanabe M,
- Organizer
  APDW2007(Asian Pacific Digestive Week 2007)
- Place of Presentation
  Kobe, Japan
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19390196
[Presentation] Expression of IFN/.4 in liver and PBMC is closely associated with higher basal expression of ISGs and impaired induction of IL28B by interferon treatment in chronic hepatitis C non-responder patients.
- Author(s)
  Murakawa M, Asahina Y, Nakagawa M, Sakamoto N, Nitta S, Kawai-Kitahata F, Taniguchi M, Watanabe T, Itsui Y, Kakinuma S, Watanabe M.
- Organizer
  The 65th Annual Meeting of the American Association for the Study of Liver Disease (AASLD The Liver Meeting 2014)
- Place of Presentation
  Boston, USA
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-24590960
[Presentation] HCV-NS4B Protein Binds STING and Blocks the RIG-I Mediated IFN Pathway.
- Author(s)
  Nitta S, Sakamoto N, Tasaka-Fujita M, Asahina Y, Watanabe M et al
- Organizer
  The 10th JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Discovery of N-(morpholine-4-carbonyloxy) amidine compounds as potent inhibitors against hepatitis C virus replication.
- Author(s)
  Kusano-Kitazume A, Sakamoto N, Asahina Y, Watanabe M et al
- Organizer
  The 10th JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] 宿主遺伝子情報に基づいたC型慢性肝炎の最適な治療法の選択
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590958
[Presentation] Impaired induction of IL28B expression in PBMC is associated with null response to interferon therapy in chronic hepatitis C.
- Author(s)
  Murakawa M, Sakamoto N, Asahina Y, Watanabe M et al
- Organizer
  19th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Venice
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] Matrix Metalloproteinase-14 による肝幹/前駆細胞分化の調節
- Author(s)
  大谷賢志、柿沼　晴、後藤文男、紙谷聡英、新田沙由梨、東　正新、中川美奈、朝比奈靖浩、坂本直哉、中内啓光、渡辺　守
- Organizer
  第５０回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ（東京）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24590959
[Presentation] 宿主遺伝子情報に基づいたC型慢性肝炎治療の効果・安全性の最適化
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590958
[Presentation] HCV-NS4B blocks the RIG-I mediated IFN pathway through targeting of STING.
- Author(s)
  Nitta S, Sakamoto N, Tasaka-Fujita M, Asahina Y, Watanabe M et al
- Organizer
  19th International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  Venice
- Data Source
  KAKENHI-PROJECT-21590831
[Presentation] C型肝疾患コホートにおける宿主遺伝子多型およびHCV遺伝子構造と予後との関連
- Author(s)
  中川美奈、坂本直哉、朝比奈靖浩
- Organizer
  第16回日本肝臓学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590958
[Presentation] 慢性肝疾患における肝細胞癌とIL-6の関連
- Author(s)
  中川美奈、坂本直哉、渡辺守
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24590958
[Presentation] 細胞障害性HCV-JFH1subcloneの単離と機能解析
- Author(s)
  三島果子、坂本直哉、筬島裕子、中川美奈、藤田めぐみ、櫻井幸、須田剛生、唐鎌優子、山本満千、渡辺貴子、植山真由美、船岡祐介、幾世橋佳、新田沙由梨、北詰晶子、井津井康浩、柿沼晴、陳正新、脇田隆字、渡辺守
- Organizer
  京都(ポスター)
- Data Source
  KAKENHI-PROJECT-21590832
[Presentation] 難治性C型慢性肝炎におけるIFN応答性に関与する要因とテラプレビル3剤併用療法の効果
- Author(s)
  中川美奈、坂本直哉、朝比奈靖浩
- Organizer
  第16回日本肝臓学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590958

1. SUDA Goki (20447460)

# of Collaborated Projects: 18 results

# of Collaborated Products: 84 results
2. WATANABE Mamoru (10175127)

# of Collaborated Projects: 17 results

# of Collaborated Products: 198 results
3. KAKINUMA Sei (30372444)

# of Collaborated Projects: 12 results

# of Collaborated Products: 86 results
4. CHEN Cheng-hsin (10376783)

# of Collaborated Projects: 9 results

# of Collaborated Products: 113 results
5. NAKAGAWA Mina (30401342)

# of Collaborated Projects: 8 results

# of Collaborated Products: 117 results
6. Morikawa Kenichi (60384377)

# of Collaborated Projects: 7 results

# of Collaborated Products: 63 results
7. ASAHINA Yasuhiro (00422692)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
8. ENOMOTO Nobuyuki (20251530)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
9. OOOKA Shinya (90361691)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
10. ITSUI Yasuhiro (20401341)

# of Collaborated Projects: 4 results

# of Collaborated Products: 28 results
11. 古川潤一 (30374193)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
12. TASAKA Megumi (50510369)

# of Collaborated Projects: 3 results

# of Collaborated Products: 50 results
13. 大西俊介 (10443475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
14. koji ogawa (20735188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
15. OSAJIMA Yuko (40451934)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
16. Sho Takuya (50581104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
17. 黒崎雅之 (10280976)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
18. KAMIYA Akihide (30321904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. SUZUKI Shinji (10456212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
20. NAKANISHI Mitsuru (10392250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. Makoto Chuma (30360910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
22. ENDO TOSHINORI (00323692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAKAMOTO Minoru (60324191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
24. ARAKI Akihiro (80361690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Teshima Takanori (40284096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 櫻井幸 (70547455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. 武井則雄 (50523461)

# of Collaborated Projects: 1 results

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28. 冨塚一磨 (40444640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. TSUMOTO Hiroki

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# of Collaborated Products: 1 results
30. Kamimura Daisuke

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# of Collaborated Products: 1 results
31. Arima Yasunobu

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# of Collaborated Products: 1 results
32. MASAKI Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. HATANAKA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. SHINKAI Noboru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. YUYAMA Kohei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. KAZUMOTO Murata

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. ITO Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. SUGIYAMA Masasya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. MAEHARA Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 夏井坂光輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 川岸直樹

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# of Collaborated Products: 2 results
42. 加藤宣之

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# of Collaborated Products: 1 results
43. 前川伸哉

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# of Collaborated Products: 2 results
44. 橋本大吾

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# of Collaborated Products: 1 results
45. 中村哲也

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# of Collaborated Products: 1 results
46. 下遠野邦忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 中井正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. 村上正晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 大原正嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 三橋智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 山本健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 米山光俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 藤原圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 脇田隆字

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 溝上雅史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAMOTO NAOYA 坂本 直哉

SAKAMOTO Naoya 坂本 直哉

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肝線維化に関連する宿主因子を標的とした新規治療法の開発Principal Investigator

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Development of novel CAR-T therapy targeting hepatic stellate cell-specific oligosaccharide antigensPrincipal Investigator

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Comprehensive search for host factors related to liver fibrosis mechanisms and development of novel therapeutic strategiesPrincipal Investigator

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Targeting the glycosylated structure of liver tissue stromal proteins to form the basis for glycosylation drug discovery for liver fibrosis.Principal Investigator

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Comprehensive screening of miviroenvirinmental factors that affect liver fibrosisPrincipal Investigator

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Development of drugs targeting liver fibrosis by modulation of protein/lipid glycosylationPrincipal Investigator

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SAKAMOTO NAOYA 坂本直哉

SAKAMOTO Naoya 坂本直哉