Takeuchi Osamu 竹内理

… Alternative Names

TAKEUCHI Osamu 竹内理

竹内理タケウチオサム

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Researcher Number	10379092
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2025: 京都大学, 医学研究科, 教授 2018: 京都大学, ウイルス・再生医科学研究所, 教授 2015: 京都大学, ウイルス研究所, 教授 2012: 京都大学, ウイルス研究所, 教授 2008 – 2012: 大阪大学, 微生物病研究所, 准教授 2005 – 2006: 大阪大学, 微生物病研究所, 助手
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Immunology / Transformative Research Areas, Section (III) / Basic Section 48040:Medical biochemistry-related / Broad Section H Except Principal Investigator Immunology / Biological Sciences
Keywords	Principal Investigator 免疫応答 / ｍRNA分解 / mRNA分解 / サイトカイン / mRNA制御 / 自然免疫応答 / 自然免疫 / mRNA安定性 / シグナル伝達 / コドン … More / 細胞傷害性T細胞 / RNA分解酵素 / T細胞 / RNA分解 / コドンバイアス / 転写後制御 / 免疫制御 / mRNA修飾 / 免疫細胞分化 / 核酸医薬 / 炎症性疾患 / Toll-like receptor / プロテオソーム / ユビキチン化 / Zc3h12a / IkBキナーゼ / RNA安定性 / 炎症 / 樹状細胞 / ウイルス / ヘリカーゼ / インターフェロン … More Except Principal Investigator 自己免疫疾患 / サイトカインストーム / 感染・炎症 / インフルエンザ / Regnase-1 / Arid5a / Th17細胞 / STAT分子 / IL-6 mRNA / 転写後調節 / RNA結合タンパク質 / RNA安定性制御 / T細胞過剰活性化 / オートファジー / 病原体センサー / ユビキチン化 / H3K27メチル化 / エピジェネティクス / Toll-like receptor / 遺伝子発現 / 蛋白質分解 / シグナル伝達 / パターン認識受容体 / 好中球 / マクロファージ / 炎症 / 生活習慣病 / インターフェロン / サイトカイン / 感染症 / 炎症性疾患 / 自然免疫 Less

内在性レトロウイルスに起因する撹乱RNAの安定性制御機構の解明Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
抗腫瘍T細胞応答を調節する転写後制御機構の解析Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2024
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
mRNA結合タンパク質による免疫制御機構の解明Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
抗腫瘍T細胞応答を調節する転写後制御機構の解析Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kyoto University
コドンに隠された暗号の解明：ヒトコドン最適化制御による治療戦略Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kyoto University
Analysis of immune regulatory mechanisms mediated by mRNA metabolismPrincipal Investigator
- Principal Investigator
  
  Takeuchi Osamu
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  Kyoto University
Control of immune responses via spatiotemporal regulation of mRNA decayPrincipal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kyoto University
The pathogenic role of Arid5a in infection and autoimmunity.
- Principal Investigator
  
  MASUDA Kazuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
Analysis of the mechanisms of an RNase, Zc3h12a-mediated immune regulation.Principal Investigator
- Principal Investigator
  
  TAKEUCHI Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
  Osaka University
Comprehensive study of innate immunity
- Principal Investigator
  
  AKIRA Shizuo
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
自然免疫系によるウイルス特異的分子パターン認識機構の解析Principal Investigator
- Principal Investigator
  
  竹内理
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University

[Book] RNA Damage and Repair2021
- Author(s)
  Hia F and Takeuchi O
- Total Pages
  24
- Publisher
  Springer International Publishing
- ISBN
  9783030765705
- Data Source
  KAKENHI-PROJECT-18H05278
[Book] RNA Damage and Repair (The Role of Ribonucleases in RNA Damage, Inactivation and Degradation)2021
- Author(s)
  Hia F, Takeuchi O
- Total Pages
  24
- Publisher
  Springer Cham
- ISBN
  9783030765712
- Data Source
  KAKENHI-PROJECT-20F20115
[Book] Innate immunity.Encyclop.Mol.Cell Biol.Mol.Med.2nd Ed.Vol.72005
- Author(s)
  Takeuchi O, Akira S.
- Total Pages
  22
- Publisher
  Wiley, VCH, Weinheim
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] RNA Metabolism Governs Immune Function and Response2024
- Author(s)
  Yoshinaga Masanori、Takeuchi Osamu
- Journal Title
  
  Advances in experimental medicine and biology
  
  Volume: 1444 Pages: 145-161
- DOI
  10.1007/978-981-99-9781-7_10
- ISBN
  9789819997800, 9789819997817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-23H00402
[Journal Article] Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz2024
- Author(s)
  3.Uehata T, Yamada S, Ori D, Vandenbon A, Giladi A, Jelinski A, Murakawa Y, Watanabe H, Takeuchi K, Toratani K, Mino T, Kiryu H, Standley DM, Tsujimura T, IkawaT, Kondoh G, Landthaler M, Kawamoto H, Rodewald HR, Amit I, Yamamoto R, Miyazaki M, Takeuchi O
- Journal Title
  
  Blood
  
  Volume: 143 Issue: 3 Pages: 243-257
- DOI
  10.1182/blood.2023020903
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0209, KAKENHI-PROJECT-23K11299, KAKENHI-PROJECT-20K12059, KAKENHI-PROJECT-22K19430, KAKENHI-PROJECT-22KF0226, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23H00402, KAKENHI-PROJECT-23K27425
[Journal Article] Regulation of inflammatory diseases via the control of mRNA decay2024
- Author(s)
  Yoshinaga Masanori、Takeuchi Osamu
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 44 Issue: 1 Pages: 14-14
- DOI
  10.1186/s41232-024-00326-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-23H00402
[Journal Article] Regnase-1 plays an essential role in maintaining skin immune homeostasis via regulation of chemokine expression2023
- Author(s)
  Yang Gabsik、Lee Hye Eun、Trzeciak Magdalena、Pawelczyk Tadeusz、Takeuchi Osamu、Kang Han Chang、Cho Yong-Yeon、Lee Hye Suk、Lee Joo Young
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 162 Pages: 114558-114558
- DOI
  10.1016/j.biopha.2023.114558
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-23H00402
[Journal Article] Hyperfructosemia in sleep disordered breathing: metabolome analysis of Nagahama study2023
- Author(s)
  Nakatsuka Y, Murase K, Sonomura K, Tabara Y, Nagasaki T, Hamada S, Matsumoto T, Minami T, Kanai O, Takeyama H, Sunadome H, Takahashi N, Nakamoto I, Tanizawa K, Handa T, Sato TA, Komenami N, Wakamura T, Morita S, Takeuchi O, Nakayama T, Hirai T, Kamatani Y, Matsuda F, Chin K.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 12735-12735
- DOI
  10.1038/s41598-023-40002-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07638, KAKENHI-PROJECT-21H04850, KAKENHI-PROJECT-23H00402
[Journal Article] Innate immune sensing of pathogens and its post-transcriptional regulations by RNA-binding proteins2023
- Author(s)
  Tse Ka Man、Takeuchi Osamu
- Journal Title
  
  Archives of Pharmacal Research
  
  Volume: 46 Issue: 2 Pages: 65-77
- DOI
  10.1007/s12272-023-01429-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism2022
- Author(s)
  Chong Yee Kien、Tartey Sarang、Yoshikawa Yuki、Imami Koshi、Li Songling、Yoshinaga Masanori、Hirabayashi Ai、Liu Guohao、Vandenbon Alexis、Hia Fabian、Uehata Takuya、Mino Takashi、Suzuki Yutaka、Noda Takeshi、Ferrandon Dominique、Standley Daron M.、Ishihama Yasushi、Takeuchi Osamu
- Journal Title
  
  Science Signaling
  
  Volume: 15 Issue: 729 Pages: 1-19
- DOI
  10.1126/scisignal.abm5011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04844, KAKENHI-PUBLICLY-21H05720, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-20F20115, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-20K22737
[Journal Article] Regnase-1 Prevents Pulmonary Arterial Hypertension Through mRNA Degradation of Interleukin-6 and Platelet-Derived Growth Factor in Alveolar Macrophages2022
- Author(s)
  Yaku Ai、Inagaki Tadakatsu、Asano Ryotaro、Okazawa Makoto、Mori Hiroyoshi、Sato Ayuko、Hia Fabian、Masaki Takeshi、Manabe Yusuke、Ishibashi Tomohiko、Vandenbon Alexis、Nakatsuka Yoshinari、Akaki Kotaro、Yoshinaga Masanori、Uehata Takuya、Mino Takashi、Morita Satoshi、Ishibashi-Ueda Hatsue、Morinobu Akio et al.
- Journal Title
  
  Circulation
  
  Volume: 146 Issue: 13 Pages: 1006-1022
- DOI
  10.1161/circulationaha.122.059435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-22K16121, KAKENHI-PROJECT-18H05278
[Journal Article] The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity2022
- Author(s)
  Yoshinaga Masanori、Han Kyuho、Morgens David W.、Horii Takuro、Kobayashi Ryosuke、Tsuruyama Tatsuaki、Hia Fabian、Yasukura Shota、Kajiya Asako、Cai Ting、Cruz Pedro H. C.、Vandenbon Alexis、Suzuki Yutaka、Kawahara Yukio、Hatada Izuho、Bassik Michael C.、Takeuchi Osamu
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1-17
- DOI
  10.1038/s41467-022-34078-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-22K15026, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-18H05278
[Journal Article] DSP-crosslinking and Immunoprecipitation to Isolate Weak Protein Complex2022
- Author(s)
  Akaki Kotaro、Mino Takashi、Takeuchi Osamu
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 12 Issue: 15
- DOI
  10.21769/bioprotoc.4478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] Enhancement of Regnase-1 expression with stem loop?targeting antisense oligonucleotides alleviates inflammatory diseases2022
- Author(s)
  Tse Ka Man、Vandenbon Alexis、Cui Xiaotong、Mino Takashi、Uehata Takuya、Yasuda Keiko、Sato Ayuko、Tsujimura Tohru、Hia Fabian、Yoshinaga Masanori、Kinoshita Makoto、Okuno Tatsusada、Takeuchi Osamu
- Journal Title
  
  Science Translational Medicine
  
  Volume: 14 Issue: 644 Pages: 1-14
- DOI
  10.1126/scitranslmed.abo2137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-18H05278
[Journal Article] Enhancement of Regnase-1 expression with stem-loop-targeting antisense oligonucleotides alleviates inflammatory diseases2022
- Author(s)
  Ka Man Tse, Alexis Vandenbon, Xiaotong Cui, Takashi Mino, Takuya Uehata, Keiko Yasuda, Ayuko Sato, Tohru Tsujimura, Fabian Hia, Masanori Yoshinaga, Makoto Kinoshita, Tatsusada Okuno, Osamu Takeuchi
- Journal Title
  
  Science Translational Medicine
  
  Volume: In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] Androgens Alleviate Allergic Airway Inflammation by Suppressing Cytokine Production in Th2 Cells2022
- Author(s)
  Ejima Aki、Abe Shinya、Shimba Akihiro、Sato Susumu、Uehata Takuya、Tani-ichi Shizue、Munakata Satoru、Cui Guangwei、Takeuchi Osamu、Hirai Toyohiro、Kato Shigeaki、Ikuta Koichi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 209 Issue: 6 Pages: 1083-1094
- DOI
  10.4049/jimmunol.2200294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-20H03501
[Journal Article] Posttranscriptional regulation of ILC2 homeostatic function via tristetraprolin2021
- Author(s)
  Hikichi Yuki、Motomura Yasutaka、Takeuchi Osamu、Moro Kazuyo
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218 Issue: 12
- DOI
  10.1084/jem.20210181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H05286, KAKENHI-PROJECT-21F21115
[Journal Article] PIN and CCCH Zn-finger domains coordinate RNA targeting in ZC3H12 family endoribonucleases2021
- Author(s)
  Garg Ankur、Roske Yvette、Yamada Shinnosuke、Uehata Takuya、Takeuchi Osamu、Heinemann Udo
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 9 Pages: 5369-5381
- DOI
  10.1093/nar/gkab316
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-21K07079
[Journal Article] Extracellular mRNA transported to the nucleus exerts translation-independent function2021
- Author(s)
  Tomita Takeshi、Kato Masayoshi、Mishima Taishi、Matsunaga Yuta、Sanjo Hideki、Ito Ken-ichi、Minagawa Kentaro、Matsui Toshimitsu、Oikawa Hiroyuki、Takahashi Satoshi、Takao Toshifumi、Iwai Noriki、Mino Takashi、Takeuchi Osamu、Maru Yoshiro、Hiratsuka Sachie
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3655-3655
- DOI
  10.1038/s41467-021-23969-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06577, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-19H03500, KAKENHI-PROJECT-20K06554, KAKENHI-PROJECT-21K06868, KAKENHI-PROJECT-19H03506, KAKENHI-PROJECT-21H02438
[Journal Article] Post-transcriptional regulation of immunological responses by Regnase-1-related RNases2021
- Author(s)
  Uehata Takuya、Takeuchi Osamu
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 859-865
- DOI
  10.1093/intimm/dxab048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-21K07079
[Journal Article] IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay2021
- Author(s)
  Akaki Kotaro、Ogata Kosuke、Yamauchi Yuhei、Iwai Noriki、Tse Ka Man、Hia Fabian、Mochizuki Atsushi、Ishihama Yasushi、Mino Takashi、Takeuchi Osamu
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.71966
- NAID
  120007166024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-19J23450, KAKENHI-PROJECT-20F20115, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19H03196, KAKENHI-PLANNED-19H05678
[Journal Article] Regnase‐1-related endoribonucleases in health and immunological diseases2021
- Author(s)
  Mino Takashi、Takeuchi Osamu
- Journal Title
  
  Immunological Reviews
  
  Volume: 304 Issue: 1 Pages: 97-110
- DOI
  10.1111/imr.13023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-16H06279
[Journal Article] TANK prevents IFN-dependent fatal diffuse alveolar hemorrhage by suppressing DNA-cGAS aggregation2021
- Author(s)
  Wakabayashi Atsuko、Yoshinaga Masanori、Takeuchi Osamu
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 2 Pages: e202101067-e202101067
- DOI
  10.26508/lsa.202101067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-21K15372, KAKENHI-PROJECT-20K22737
[Journal Article] The effects of codon bias and optimality on mRNA and protein regulation2020
- Author(s)
  Hia Fabian、Takeuchi Osamu
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: 78 Issue: 5 Pages: 1909-1928
- DOI
  10.1007/s00018-020-03685-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-20F20115, KAKENHI-PROJECT-16H06279
[Journal Article] RNA Recognition and Immunity?Innate Immune Sensing and Its Posttranscriptional Regulation Mechanisms2020
- Author(s)
  Uehata Takuya、Takeuchi Osamu
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 7 Pages: 1701-1701
- DOI
  10.3390/cells9071701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-18K15185
[Journal Article] The transcription factor E2A activates multiple enhancers that drive Rag expression in developing T and B cells2020
- Author(s)
  Miyazaki Kazuko、Watanabe Hitomi、Yoshikawa Genki、Chen Kenian、Hidaka Reiko、Aitani Yuki、Osawa Kai、Takeda Rie、Ochi Yotaro、Tani-ichi Shizue、Uehata Takuya、Takeuchi Osamu、Ikuta Koichi、Ogawa Seishi、Kondoh Gen、Lin Yin C.、Ogata Hiroyuki、Miyazaki Masaki
- Journal Title
  
  Science Immunology
  
  Volume: 5 Issue: 51 Pages: 1455-1455
- DOI
  10.1126/sciimmunol.abb1455
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03487, KAKENHI-PROJECT-19J13775, KAKENHI-PROJECT-18K15185
[Journal Article] Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages2020
- Author(s)
  Maruyama Kenta、Kidoya Hiroyasu、Takemura Naoki、Sugisawa Erika、Takeuchi Osamu、Kondo Takeshi、Eid Mohammed Mansour Abbas、Tanaka Hiroki、Martino Mika?l M.、Takakura Nobuyuki、Takayama Yasunori、Akira Shizuo、Vandenbon Alexis、Kumagai Yutaro
- Journal Title
  
  Cell Reports
  
  Volume: 32 Issue: 2 Pages: 107906-107906
- DOI
  10.1016/j.celrep.2020.107906
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H02970, KAKENHI-PROJECT-19K22712, KAKENHI-PROJECT-18KT0070, KAKENHI-PROJECT-20H00516, KAKENHI-PROJECT-18K19475
[Journal Article] Live-Cell Imaging of Protein Degradation Utilizing Designed Protein-Tag Mutant and Fluorescent Probe with Turn-Off Switch2020
- Author(s)
  Gao J, Hori Y, Takeuchi O, Kikuchi K
- Journal Title
  
  Bioconjug Chem
  
  Volume: 31 Issue: 3 Pages: 577-583
- DOI
  10.1021/acs.bioconjchem.9b00696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19402, KAKENHI-PROJECT-19K22255, KAKENHI-PUBLICLY-18H04735, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H03935, KAKENHI-PROJECT-18F18116, KAKENHI-PROJECT-19J12178, KAKENHI-PLANNED-17H06409
[Journal Article] Profibrotic function of pulmonary group 2 innate lymphoid cells is controlled by regnase-12020
- Author(s)
  Nakatsuka Yoshinari、Yaku Ai、Handa Tomohiro、Vandenbon Alexis、Hikichi Yuki、Motomura Yasutaka、Sato Ayuko、Yoshinaga Masanori、Tanizawa Kiminobu、Watanabe Kizuku、Hirai Toyohiro、Chin Kazuo、Suzuki Yutaka、Uehata Takuya、Mino Takashi、Tsujimura Tohru、Moro Kazuyo、Takeuchi Osamu
- Journal Title
  
  European Respiratory Journal
  
  Volume: 57 Issue: 3 Pages: 2000018-2000018
- DOI
  10.1183/13993003.00018-2020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H05286, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-20K22737, KAKENHI-PROJECT-18K15185
[Journal Article] Codon bias confers stability to human mRNAs2019
- Author(s)
  Hia Fabian、Yang Sheng Fan、Shichino Yuichi、Yoshinaga Masanori、Murakawa Yasuhiro、Vandenbon Alexis、Fukao Akira、Fujiwara Toshinobu、Landthaler Markus、Natsume Tohru、Adachi Shungo、Iwasaki Shintaro、Takeuchi Osamu
- Journal Title
  
  EMBO reports
  
  Volume: 20 Issue: 11
- DOI
  10.15252/embr.201948220
- NAID
  120006767912
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H03992, KAKENHI-PROJECT-19J00920, KAKENHI-PROJECT-19K22406, KAKENHI-PROJECT-17H04998
[Journal Article] RNA binding proteins in the control of autoimmune diseases2019
- Author(s)
  Yoshinaga Masanori、Takeuchi Osamu
- Journal Title
  
  Immunological Medicine
  
  Volume: 42 Issue: 2 Pages: 53-64
- DOI
  10.1080/25785826.2019.1655192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.2019
- Author(s)
  Yamasoba D, Sato K, Ichinose T, Imamura T, Koepke L, Joas S, Reith E, Hotter D, Misawa N, Akaki K, Uehata T, Mino T, Miyamoto S, Noda T, Yamashita A, Standley DM, Kirchhoff F, Sauter D, Koyanagi Y, Takeuchi O.
- Journal Title
  
  Nat Microbiol
  
  Volume: 4 Issue: 9 Pages: 1532-1544
- DOI
  10.1038/s41564-019-0460-3
- NAID
  120006731123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22529, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18KK0447, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-17H04082, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-18H02662, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-17J10132, KAKENHI-PROJECT-18K15185
[Journal Article] Translation-dependent unwinding of stem?loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs2019
- Author(s)
  Mino Takashi、Iwai Noriki、Endo Masayuki、Inoue Kentaro、Akaki Kotaro、Hia Fabian、Uehata Takuya、Emura Tomoko、Hidaka Kumi、Suzuki Yutaka、Standley Daron M、Okada-Hatakeyama Mariko、Ohno Shigeo、Sugiyama Hiroshi、Yamashita Akio、Takeuchi Osamu
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 47 Pages: 8838-8859
- DOI
  10.1093/nar/gkz628
- NAID
  120006708220
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-18KK0139, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-19H03488, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-16H06356, KAKENHI-PROJECT-18K15185
[Journal Article] Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis2019
- Author(s)
  Kakiuchi Nobuyuki et al.
- Journal Title
  
  Nature
  
  Volume: 577 Issue: 7789 Pages: 260-265
- DOI
  10.1038/s41586-019-1856-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07224, KAKENHI-PROJECT-18K15747, KAKENHI-PROJECT-18K16084, KAKENHI-PLANNED-15H05909, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-19H04806, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H01053, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-19H03560, KAKENHI-PROJECT-17J05245, KAKENHI-PROJECT-15H05707, KAKENHI-PROJECT-18H05278
[Journal Article] Post‐transcriptional control of immune responses and its potential application2019
- Author(s)
  Yoshinaga Masanori、Takeuchi Osamu
- Journal Title
  
  Clinical & Translational Immunology
  
  Volume: 8 Issue: 6
- DOI
  10.1002/cti2.1063
- NAID
  120006784407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation2019
- Author(s)
  Yamasoba D, Sato K, Ichinose T, Imamura T, Koepke L, Joas S, Reith E, Hotter D, Misawa N, Akaki K, Uehata T, Mino T, Miyamoto S, Noda T, Yamashita A, Standley DM, Kirchhoff F, Sauter D, Koyanagi Y, Takeuchi O.
- Journal Title
  
  Nature Microbiology
  
  Volume: 印刷中
- NAID
  120006731123
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Journal Article] NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements2019
- Author(s)
  Hirabayashi Shigeki、Bhagat Shruti、Matsuki Yu、Takegami Yujiro、Uehata Takuya、Kanemaru Ai、Itoh Masayoshi、Shirakawa Kotaro、Takaori-Kondo Akifumi、Takeuchi Osamu、Carninci Piero、Katayama Shintaro、Hayashizaki Yoshihide、Kere Juha、Kawaji Hideya、Murakawa Yasuhiro
- Journal Title
  
  Nature Genetics
  
  Volume: 51 Issue: 9 Pages: 1369-1379
- DOI
  10.1038/s41588-019-0485-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H03992, KAKENHI-PROJECT-16H02902, KAKENHI-PROJECT-18K15185
[Journal Article] Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia2018
- Author(s)
  Nakatsuka Yoshinari、Vandenbon Alexis、Mino Takashi、Yoshinaga Masanori、Uehata Takuya、Cui Xiaotong、Sato Ayuko、Tsujimura Tohru、Suzuki Yutaka、Sato Atsuyasu、Handa Tomohiro、Chin Kazuo、Sawa Teiji、Hirai Toyohiro、Takeuchi Osamu
- Journal Title
  
  Mucosal Immunology
  
  Volume: AOP Issue: 4 Pages: 1203-1218
- DOI
  10.1038/s41385-018-0024-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J08040, KAKENHI-PROJECT-17K08731, KAKENHI-PROJECT-18K15185, KAKENHI-PROJECT-15H05713, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H04027, KAKENHI-PROJECT-18H02905, KAKENHI-PROJECT-16K08832, KAKENHI-PROJECT-16H06279
[Journal Article] Hassall’s corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus2018
- Author(s)
  Wang Jianwei、Sekai Miho、Matsui Takeshi、Fujii Yosuke、Matsumoto Mitsuru、Takeuchi Osamu、Minato Nagahiro、Hamazaki Yoko
- Journal Title
  
  International Immunology
  
  Volume: 31 Issue: 3 Pages: 127-139
- DOI
  10.1093/intimm/dxy073
- NAID
  120007164929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-19K16689, KAKENHI-PROJECT-15K19125, KAKENHI-PUBLICLY-17H05641, KAKENHI-PROJECT-18H02640, KAKENHI-PROJECT-18K19442
[Journal Article] Post-transcriptional regulation of immune responses by RNA binding proteins2018
- Author(s)
  MINO Takashi、TAKEUCHI Osamu
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 94 Issue: 6 Pages: 248-258
- DOI
  10.2183/pjab.94.017
- NAID
  130007395766
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2018-06-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-18H04027, KAKENHI-PROJECT-16K08832
[Journal Article] Translation of Hepatitis A Virus IRES Is Upregulated by a Hepatic Cell-Specific Factor2018
- Author(s)
  Sadahiro Akitoshi、Fukao Akira、Kosaka Mio、Funakami Yoshinori、Takizawa Naoki、Takeuchi Osamu、Duncan Kent E.、Fujiwara Toshinobu
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 9 Pages: 1-10
- DOI
  10.3389/fgene.2018.00307
- NAID
  120006534584
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05607, KAKENHI-PROJECT-18H05278, KAKENHI-PROJECT-16H04745, KAKENHI-PROJECT-17J07163, KAKENHI-PROJECT-16K09271, KAKENHI-PROJECT-16K14652
[Journal Article] Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA2016
- Author(s)
  Masuda, K., Ripley, B., Nyati, K., Dubey, P., Zaman, M., Hanieh, H., Hoga, M., Yamashita, K., Standley, D., Mashima, T., Katahira, M., Okamoto, T., Matsuura, Y., Takeuchi, O. and Kishimoto, T.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 213 Issue: 4 Pages: 605-619
- DOI
  10.1084/jem.20151289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00813, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-26860328, KAKENHI-PROJECT-15H04736
[Journal Article] Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages2013
- Author(s)
  Satoh T, Kidoya H, Naito H, Yamamoto M,Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S
- Journal Title
  
  Nature
  
  Volume: 495 Pages: 524-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation2013
- Author(s)
  Uehata T, Iwasaki H, Vandenbon A, Matsushita K, Hernandez Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O and Akira S
- Journal Title
  
  Cell
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation2013
- Author(s)
  Uehata T, Iwasaki H, Vandenbon A, Matsushita, K, Hernandez Cuellar E, Kuniyoshi K, Satoh T, Mino T, Suzuki Y, Standley DM, Tsujimura T, Rakugi H, Isaka Y, Takeuchi O and Akira S
- Journal Title
  
  Cell
  
  Volume: 23;153 Issue: 5 Pages: 1036-49
- DOI
  10.1016/j.cell.2013.04.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-24790484, KAKENHI-PROJECT-25860355
[Journal Article] Critical Role of AZI2 in GM-CSF-Induced Dendritic Cell Differentiation.2013
- Author(s)
  Fukasaka M, Ori D, Kawagoe T, Uematsu S, Maruyama K, Okazaki T, Kozaki T, Imamura T, Tartey S, Mino T, Satoh T, Akira S, Takeuchi O.
- Journal Title
  
  J Immunol.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] Critical role of Trib1 for the differentiation of adipose tissue-resident macrophages maintaining metabolic homeostasis.2013
- Author(s)
  Satoh T, Kidoya H, Naito H, Yamamoto M, Takemura N, Nakagawa K, Yoshioka Y, Morii E, Takakura N, Takeuchi O, Akira S
- Journal Title
  
  Nature
  
  Volume: 495(7442) Issue: 7442 Pages: 524-528
- DOI
  10.1038/nature11930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008, KAKENHI-PROJECT-22613004, KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-23590425, KAKENHI-PROJECT-23701054, KAKENHI-PROJECT-25830080, KAKENHI-PLANNED-22112005, KAKENHI-PUBLICLY-23122511
[Journal Article] Essential Roles of K63-Linked Polyubiquitin-Binding Proteins TAB2 and TAB3 in B Cell Activaion via MAPKs.2013
- Author(s)
  Ori D
- Journal Title
  
  J Immunol
  
  Volume: 190(8) Issue: 8 Pages: 4037-4045
- DOI
  10.4049/jimmunol.1300173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008, KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-23790438, KAKENHI-PROJECT-25860355
[Journal Article] Critical Role of AZI2 in GM-CSF-Induced Dendritic Cell Differentiation2013
- Author(s)
  Fukasaka M, Ori D, Kawagoe T, Uematsu S, Maruyama K, Okazaki T, Kozaki T, Imamura T, Tartey S, Mino T, Satoh T, Akira S, Takeuchi O
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 11 Pages: 5702-11
- DOI
  10.4049/jimmunol.1203155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-24590582, KAKENHI-PROJECT-25860355
[Journal Article] The transcription factor Jun dimerization protein 2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation2012
- Author(s)
  kenta Maruyama, Masahiro Fukasaka, Alexis Vandenbon, Tatsuya Saitoh, Takumi Kawasaki, Takeshi Kondo, Kazunari K. Yokoyama, Hiroyasu Kidoya, Nobuyuki Takakura, Daron Standley, Osamu Takeuchi, and Shizuo Akira
- Journal Title
  
  Immunity
  
  Volume: 37 Issue: 6 Pages: 1024-1036
- DOI
  10.1016/j.immuni.2012.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00081, KAKENHI-PROJECT-20002008, KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-23701054, KAKENHI-PROJECT-24300330, KAKENHI-PLANNED-22112005, KAKENHI-PUBLICLY-23122511
[Journal Article] The toll-like receptor 3-mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice2012
- Author(s)
  Abe Y, Fujii K, Nagata N, Takeuchi O, Akira S, Oshiumi H, Matsumoto M, Seya T, Koike S
- Journal Title
  
  J Virol
  
  Volume: 86 Pages: 185-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] TRAF family member-associated NF-_<K>B activator (TANK) is a negative regulator of osteoclastogenesis and bone formation2012
- Author(s)
  kenta Maruyama, Tatsukata Kawagoe, Takeshi Kondo, Shizuo Akira, and Osamu Takeuchi.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Issue: 34 Pages: 29114-29124
- DOI
  10.1074/jbc.m112.347799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00081, KAKENHI-PROJECT-22689016
[Journal Article] Epigenetic control of macrophage polarization2011
- Author(s)
  Takeuchi O, et al
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Issue: 9 Pages: 2490-2493
- DOI
  10.1002/eji.201141792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-12011
- Author(s)
  Iwasaki H, Takeuchi O, Teraguchi S, Matsushita K, Uehata T, Kuniyoshi K, Satoh T, Saitoh T, Matsushita M, Standley DM, Akira S
- Journal Title
  
  Nature Immunology
  
  Volume: 12 Pages: 1167-1175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] The TRAF-associated protein TANK facilitates cross-talk within the IkappaB kinase family during Toll-like receptor signaling2011
- Author(s)
  Clark K, Takeuchi O, Akira S, Cohen P
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 108 Pages: 17093-17098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.2011
- Author(s)
  Saitoh T, Satoh T, Yamamoto N, Uematsu S, Takeuchi O, Kawai T, Akira S.
- Journal Title
  
  Immunity.
  
  Volume: 34 Issue: 3 Pages: 352-363
- DOI
  10.1016/j.immuni.2011.03.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR-IL-1R by controlling degradation of regnase-1.2011
- Author(s)
  Iwasaki H, Takeuchi O, Teraguchi S, Matsushita K, Uehata T, Kuniyoshi K, Satoh T, Saitoh T, Matsushita M, Standley DM, Akira S.
- Journal Title
  
  Nat Immunol.
  
  Volume: 12 Issue: 12 Pages: 1167-1175
- DOI
  10.1038/ni.2137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008, KAKENHI-PROJECT-21570169, KAKENHI-PROJECT-22689016, KAKENHI-PROJECT-22890224
[Journal Article] Pattern recognition receptors and inflammation.2010
- Author(s)
  Takeuchi, O., Akira, S.
- Journal Title
  
  Cell
  
  Volume: 6 Pages: 805-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] The Jmjd3-Irf4 axis regulates M2 macropharge polarization and host responses against helminth infection.2010
- Author(s)
  Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Kumagai, Y., Miyake, T., Matsuyama, T., Yui K., Okazaki, T., Saitoh, T., Honma, K., Nakai, K., Akira, S.
- Journal Title
  
  Nat Immunol
  
  Volume: 11 Pages: 936-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] Pattern recognition receptors and inflammation.2010
- Author(s)
  Takeuchi O, Akira S
- Journal Title
  
  Cell
  
  Volume: 140(6) Issue: 6 Pages: 805-20
- DOI
  10.1016/j.cell.2010.01.022
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] p53 controls radiation-induced gastrointestinal syndrome in mice independent of apoptosis.2010
- Author(s)
  Kirsch DG, Santiago PM, di Tomaso E, Sullivan JM, Hou WS, Dayton T, Jeffords LB, Sodha P, Mercer KL, Cohen R, Takeuchi O, Korsmeyer SJ, Bronson RT, Kim CF, Haigis KM, Jain RK, Jacks T.
- Journal Title
  
  Science
  
  Volume: 327 Pages: 593-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] I{kappa}B{zeta} is essential for natural killer cell activation in response to IL-12 and IL-18.2010
- Author(s)
  Miyake, T., Satoh, T., Kato, H., Matsushita, K., Kumagai, Y., Vandenbon, A., Tani, T., Muta, T., Akira, S., Takeuchi, O.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107(41) Pages: 17680-17685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] The Jmjd3-Irf4 axis regulates M2 macropharge polarization and host responses against helminth infection.2010
- Author(s)
  Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Kumagai Y, Miyake T, Matsuyama T, Yui K, Okazaki T, Saitoh T, Honma K, Nakai,K Akira S.
- Journal Title
  
  Nat Immunol.
  
  Volume: 11(10) Issue: 10 Pages: 936-944
- DOI
  10.1038/ni.1920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] An Slfn2 mutation causes lymphoid and myeloid immunodeficiency due to loss of immune cell quiescence.2010
- Author(s)
  Berger M, Krebs P, Crozat K, Li X, Croker BA, Siggs OM, Popkin D, Du X, Lawson BR, Theofilopoulos AN, Xia Y, Khovananth K, Y Moresco EM, Satoh T, Takeuchi O, Akira S, Beutler B.
- Journal Title
  
  Nat Immunol
  
  Volume: 11 Pages: 335-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] IκBζ Is Essential for Natural Killer Cell Activation in Response to IL-12 and IL-182010
- Author(s)
  Miyake, T., Satoh, T., Kato, H., Matsushita, K., Kumagai, Y., Vandenbon, A., Tani, T., Muta, T., Akira, S., Takeuchi, O.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Issue: 41 Pages: 17680-17685
- DOI
  10.1073/pnas.1012977107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.2010
- Author(s)
  Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH
- Journal Title
  
  Science
  
  Volume: 330 Pages: 1390-1393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] The Jmjd3-lrf4 axis regulates M2 macropharge polarization and host responses against helminth infection.2010
- Author(s)
  Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Kumagai, Y., Miyake, T., Matsuyama, T., Yui, K., Okazaki, T., Saitoh, T., Honma, K., Nakai, K.and Akira, S.
- Journal Title
  
  Nat Immunol. 11(10)
  
  Pages: 936-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] I{kappa}B{zeta} is essential for natural killer cell activation in response to IL-12 and IL-18.2010
- Author(s)
  Miyake, T., Satoh, T., Kato, H., Matsushita, K., Kumagai, Y., Vandenbon, A., Tani, T., Muta, T., Akira, S., Takeuchi, O.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107 Pages: 17680-17685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689016
[Journal Article] The Jmjd3-Irf4 axis regulates M2 macropharge polarization and host responses against helminth infection.2010
- Author(s)
  Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Kumagai, Y., Miyake, T., Matsuyama, T., Yui, K., Okazaki, T., Saitoh, T., Honma, K., Nakai, K., Akira, S.
- Journal Title
  
  Nat Immunol
  
  Volume: 11(10) Pages: 936-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Pattern recognition receptors and inflammation.2010
- Author(s)
  Takeuchi, O., Akira, S.
- Journal Title
  
  Cell 140(6)
  
  Pages: 805-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Pattern recognition receptors and inflammation.2010
- Author(s)
  Takeuchi, O., Akira, S.
- Journal Title
  
  Cell
  
  Volume: 140(6) Pages: 805-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.2010
- Author(s)
  Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.
- Journal Title
  
  Proc Natl Acad Sci USA. 107(4)
  
  Pages: 1512-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-(alpha) production in plasmacytoid dendritic cells.2009
- Author(s)
  Kumagai Y, Kumar H, Koyama S, Kawai T, Takeuchi O, Akira S.
- Journal Title
  
  J Immunol. 182(7)
  
  Pages: 3960-3964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.2009
- Author(s)
  Kawagoe, T., Takeuchi, O., Takabatake, Y., Kato, H., Isaka, Y., Tsujimura, T., Akira S.
- Journal Title
  
  Nat Immunol 10(9)
  
  Pages: 965-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Innate immunity to virus infection2009
- Author(s)
  Takeuchi O, Akira S.
- Journal Title
  
  Immunol Rev. 227(1)
  
  Pages: 75-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.2009
- Author(s)
  Kawagoe T^*, Takeuchi O*, Takabatake Y, Kato H, Isaka Y, Tsujimura T, Akira S.
- Journal Title
  
  Nat Immunol. 10(9)
  
  Pages: 965-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response.2009
- Author(s)
  Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T, Yamamoto N, Kawai T, Ishii K, Takeuchi O, Yoshimori T, Akira S.
- Journal Title
  
  Proc Natl Acad Sci USA. 106(49)
  
  Pages: 20842-20846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-I and TRIF-dependent pathways.2009
- Author(s)
  Miyake T, Kumagai Y, Kato H, Guo Z, Matsushita K, Satoh T, Kawagoe T, Kumar H, Jang MH, Kawai T, Tani T, Takeuchi O, Akira S.
- Journal Title
  
  J Immunol. 183(4)
  
  Pages: 2522-2528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Zc3h12a is an Base essential for controlling immune responses by regulating mRNA decay.2009
- Author(s)
  Matsushita K^*, Takeuchi O^*, Standley DM, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsuiimura T, Nakamura H, Akira S.
- Journal Title
  
  Nature. 458(7242)
  
  Pages: 1185-1190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay.2009
- Author(s)
  Matsushita K, Takeuchi O, Standley D, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato H, Tsujimura T, Nakamura H, Akira S.
- Journal Title
  
  Nature.
  
  Volume: 458(7242) Issue: 7242 Pages: 1185-1190
- DOI
  10.1038/nature07924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis.2009
- Author(s)
  Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T, Akira S.
- Journal Title
  
  Nat Immunol.
  
  Volume: 10(9) Issue: 9 Pages: 965-972
- DOI
  10.1038/ni.1771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] RIG-I-like antiviral protein in files2008
- Author(s)
  Takeuchi O, Akira S.
- Journal Title
  
  Nat Immunol 9(12)
  
  Pages: 1327-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.2008
- Author(s)
  Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, Saitoh T, Kawai T, Takeuchi O, Akira S.
- Journal Title
  
  Nat Immunol 9(6)
  
  Pages: 684-691
- NAID
  40016500618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1 beta production2008
- Author(s)
  Saitoh T, Fujita N, Jang M.H, Uematsu S, Yang B.G, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Tsujimura T, Takeuchi O, Yoshimori T, Akira S
- Journal Title
  
  Nature. 456(7219)
  
  Pages: 264-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.2008
- Author(s)
  Saitoh, T., Fujita, N., Jang, M.H., Uematsu, S., Yang, B.G., Satoh, T., Omori, H., Noda, T., Yamamoto, N., Komatsu, M., Tanaka, K., Tsujimura, T., Takeuchi, O., Yoshimori, T., Akira S.
- Journal Title
  
  Nature 456(7219)
  
  Pages: 264-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Pathogen recognition by innate receptors2008
- Author(s)
  Kumagai Y, Takeuchi O, Akira S.
- Journal Title
  
  J Infect Chemother 14(2)
  
  Pages: 86-92
- NAID
  10021193501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Length-dependent recognition of double-stranded ribonucleic acids by rethinoic acid-inducible gene-I and melanoma differentiation-associated gene 52008
- Author(s)
  Kato H, Takeuchi O, Mikamo-Satoh E, Hirai R, Kawai T, Matsushita K, Hiiragi A, Dermody T.S, Fujita T, Akira S.
- Journal Title
  
  J Exp Med. 205(7)
  
  Pages: 1601-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.2008
- Author(s)
  Saitoh T, Fujita N, Jang M.H, Uematsu S, Yang B.G, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Tsujimura T, Takeuchi O, Yoshimori T, Akira S.
- Journal Title
  
  Nature.
  
  Volume: 456(7219) Issue: 7219 Pages: 264-268
- DOI
  10.1038/nature07383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Journal Article] Essential function for the kinase TAK1 in innate and adaptive immune responses.2005
- Author(s)
  Sato S, Sanjo H, Takeda K, Ninomiya-Tsuji J, Yamamoto M, Kawai T, Matsumoto K, Takeuchi O, Akira S.
- Journal Title
  
  Nat.Immunol. 6
  
  Pages: 1087-1095
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-alpha induction.2005
- Author(s)
  Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.
- Journal Title
  
  J.Exp.Med. 201
  
  Pages: 915-923
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] Essential role of BAX, BAK in B cell homeostasis and prevention of autoimmune disease.2005
- Author(s)
  Takeuchi O, Fisher J, Suh H, Harada H, Malynn BA, Korsmeyer SJ.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102
  
  Pages: 11272-11277
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] Cell type specific involvement of RIG-I in antiviral response2005
- Author(s)
  Kato H, Sato S, Yoneyama M, Yamamoto M, Uematsu S, Matsui K, Tsujimura T, Takeda, K, Fujita, T, Takeuchi O, Akira S.
- Journal Title
  
  Immunity 23
  
  Pages: 19-28
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] A-Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.2005
- Author(s)
  Ishii KJ, Coban C, Kato H, Takahashi K, Torii.Y, Takeshita F, Ludwig H, Sutter G, Suzuki K, Hemmi H, Sato S, Yamamoto M, Uematsu S, Kawai T, Takeuchi O, Akira S.
- Journal Title
  
  Nat.Immunol. 7
  
  Pages: 40-48
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] IPS-1, an adaptor triggering RIG-I and Mda5-mediated type I interferon induction.2005
- Author(s)
  Kawai T, Takahashi K, Sato S, Coban C, Kumar H, Kato H, Ishii KJ, Takeuchi O, Akira S.
- Journal Title
  
  Nat.Immunol. 6
  
  Pages: 981-988
- Data Source
  KAKENHI-PROJECT-17790320
[Journal Article] Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay
- Author(s)
  Matsushita K, Takeuchi O, Standley D, Kumagai Y, Kawagoe T, Miyake T, Satoh T, Kato II, Tsujimura T, Nakamura H, Akira S
- Journal Title
  
  Nature (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20002008
[Patent] 炎症抑制用の組成物2023
- Inventor(s)
  竹内理
- Industrial Property Rights Holder
  竹内理
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Acquisition Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-23H00402
[Patent] がんを処置するための組成物2022
- Inventor(s)
  竹内理、植畑拓也
- Industrial Property Rights Holder
  竹内理、植畑拓也
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-088931
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-18H05278
[Patent] 肺高血圧症の検査方法、肺動脈性肺高血圧症の病態モデル動物、及び肺高血圧症の予防又は治療薬2021
- Inventor(s)
  竹内理、夜久愛、中岡良和
- Industrial Property Rights Holder
  竹内理、夜久愛、中岡良和
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-187370
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H05278
[Patent] 炎症抑制用の組成物2021
- Inventor(s)
  竹内理
- Industrial Property Rights Holder
  竹内理
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2023
- Overseas
- Data Source
  KAKENHI-PROJECT-18H05278
[Patent] 炎症抑制用の組成物2018
- Inventor(s)
  竹内理
- Industrial Property Rights Holder
  竹内理
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-054780
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Post-transcriptional regulation of the immune system by Regnase-1-like endoribonucleases2024
- Author(s)
  Osamu Takeuchi
- Organizer
  Global Immunology Summit GIS-2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Post-transcriptional regulation of the immune system by Regnase-1-like endoribonucleases2024
- Author(s)
  Osamu Takeuchi
- Organizer
  FIMSA Advanced Training Course 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Regulation of immune cell differentiation and activation by ASOs targeting mRNA structures recognized by Regnase-1-related RNases2023
- Author(s)
  Osamu Takeuchi
- Organizer
  CSHAsia Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Regulation of immune responses by a mRNA decay factor Regnase-12023
- Author(s)
  Osamu Takeuchi
- Organizer
  The ISID2023 satellite meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Regulation of the immune system via antisense oligonucleotides targeting mRNA structures recognized by RNA-binding proteins2023
- Author(s)
  Osamu Takeuchi
- Organizer
  NatsJ8
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] mRNA構造を標的とした核酸医薬による免疫制御2023
- Author(s)
  竹内理
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Regulation of immune responses by a mRNA decay factor Regnase-12023
- Author(s)
  Osamu Takeuchi
- Organizer
  The ISID2023 satellite meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] 自然免疫の制御と疾患～Regnase-1によるサイトカインmRNA制御の役割～2023
- Author(s)
  竹内理
- Organizer
  日本歯周病学会
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] Regulation of the immune system via antisense oligonucleotides targeting mRNA structures recognized by RNA-binding proteins2023
- Author(s)
  Osamu Takeuchi
- Organizer
  NatsJ8
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] 炎症制御と自己免疫疾患抑制における Regnase-1 の役割2023
- Author(s)
  竹内理
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] Regulation of immune cell differentiation and activation by ASOs targeting mRNA structures recognized by Regnase-1-related RNases2023
- Author(s)
  Osamu Takeuchi
- Organizer
  CSHAsia Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] 自然免疫の制御と疾患～Regnase-1によるサイトカインmRNA制御の役割～2023
- Author(s)
  竹内理
- Organizer
  日本歯周病学会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00402
[Presentation] 炎症制御と自己免疫疾患抑制における Regnase-1 の役割2023
- Author(s)
  竹内理
- Organizer
  第8回日本肺高血圧・肺循環学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] RNA structure profiling reveals differential accessibility of regulatory RBPs in responses to immune stimulation2022
- Author(s)
  Mino T, Hia F, Akaki K, Takeuchi O
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] mRNA制御システムとその核酸医薬への応用2022
- Author(s)
  竹内理
- Organizer
  日本核酸医薬学会第7回年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical roles of an endoribonuclease N4bp1 in regulating CD8 T cell homeostasis and cancer immunosurveillance2022
- Author(s)
  Liu GH, Chong YK, Takeuchi O
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1-mediated immune-related mRNA decay is a therapeutic target for inflammatory diseases2022
- Author(s)
  Osamu Takeuchi
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 14-3-3-mediated regulatory mechanism of Regnase-1 under inflammatory stimulation2022
- Author(s)
  赤木宏太朗, 小形公亮, 三野享史, 石濱泰, 竹内理
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Development of a novel anti-tumor nucleic acid therapy targeting RNA structure2022
- Author(s)
  植畑拓也，竹内理
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Analysis of metabolic reprogramming in macrophage utilizing genome-wide CRISPR screening2022
- Author(s)
  Yasukura S, Yoshinaga M, Bassik MC and Takeuchi O
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] mRNA分解調節による免疫・炎症疾患の制御2022
- Author(s)
  竹内理
- Organizer
  第43回日本炎症・再生医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The Regnase-1/3-Nfkbiz axis controls hematopoietic lineage priming.2022
- Author(s)
  Uehata T，Ori D，Miyazaki M，Ikawa T，Rodewald H-R，Kawamoto H，Takeuchi O.
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical role of N6-methyladenosine modification deposited by METTL16 in hematopoiesis2022
- Author(s)
  Yoshinaga M, Bassik MC, and Takeuchi O
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Molecular mechanisms of metabolic reprogramming in tumor-associated macrophages2022
- Author(s)
  Osamu Takeuchi
- Organizer
  Franco-Japanese immuno-oncology webinar series
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1による免疫応答の制御と疾患2022
- Author(s)
  竹内理
- Organizer
  第59回日本消化器免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] mRNAの制御と免疫疾患～Regnase-1の役割を中心に～2022
- Author(s)
  竹内理
- Organizer
  第20回 Osteoimmunology Forum
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Antiviral immunity and its regulation by RNA binding proteins2022
- Author(s)
  Osamu Takeuchi
- Organizer
  Japanese-German Immunology Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The 5′ untranslated region of Regnase-1 mRNA mediates protein translation through structure to regulate immune response2022
- Author(s)
  Li W, Akaki K, Mino T, and Takeuchi O
- Organizer
  第9 回CCR4-NOT研究会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical roles of an endoribonuclease N4bp1 in regulating CD8 T cell homeostasis and cancer immunosurveillance2022
- Author(s)
  Liu GH, Chong YK, Takeuchi O
- Organizer
  第51回日本免疫学術集会
- Data Source
  KAKENHI-PROJECT-22KF0226
[Presentation] The N6-methyladenosine transferase METTL16 enables erythropoiesis through safeguarding genome integrity2022
- Author(s)
  Yoshinaga M, Kawahara Y, Bassik MC, and Takeuchi　O
- Organizer
  第23回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The N6-methyladenosine transferase METTL16 enables erythropoiesis through safeguarding genome integrity2022
- Author(s)
  Yoshinaga M, Bassik MC, and Takeuchi O
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 炎症制御におけるRNA構造変化と翻訳依存性、非依存性mRNA分解2022
- Author(s)
  竹内理
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Clues to reveal the mechanism underlying Regnase-1-mRNA binding2022
- Author(s)
  Akaki K, Li W, Mino T, Takeuchi O
- Organizer
  第9 回CCR4-NOT研究会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 12.Immune regulation by targeting Regnase-1-mediated cytokine mRNA decay2022
- Author(s)
  Osamu Takeuchi
- Organizer
  The international Symposium『Cancer Immunology, Genomics and Metabolism』
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 宿主RNA結合タンパク質によるウイルス感染免疫応答と制御2022
- Author(s)
  竹内理
- Organizer
  千里ライフサイエンスセミナーＴ３「感染症における免疫制御機構」
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Post-transcriptional regulation of hematopoietic stem and progenitor cell lineage priming by Rnases Regnase-1/-3 via Nfkbiz mRNA decay2021
- Author(s)
  Takuya Uehata, Daisuke Ori, Masaki Miyazaki, Amir Giladi, Tomokatsu Ikawa, Hiroshi Kawamoto, Ido Amit, Osamu Takeuchi
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 炎症によるmRNA制御を介した免疫細胞分化運命決定の調節機構2021
- Author(s)
  竹内理
- Organizer
  第73回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulation of Regnase-1 mRNA stability by antisense oligonucleotides alleviates inflammatory responses in pulmonary and autoimmune diseases2021
- Author(s)
  Ka Man Tse, Xiaotong Cui, Alexis Vandenbon, Keiko Yasuda, Takuya Uehata, Ayuko Sato, Tohru Tsujimura, Masanori Yoshinaga, Tatsusada Okuno, Yoshinari Nakatsuka, Osamu Takeuchi
- Organizer
  KAI International Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Antiviral innate immunity targeting RNA2021
- Author(s)
  Osamu Takeuchi
- Organizer
  European Congress Immunology (ECI) 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Unexpected role of atypical cyclin in mediating macrophage functionality via metabolic regulation2021
- Author(s)
  Yee Kien Chong, Osamu Takeuchi
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 赤芽球分化を制御する新規転写後調節機構の解明2021
- Author(s)
  吉永正憲、竹内理
- Organizer
  第44回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 免疫細胞制御における翻訳とmRNA分解2021
- Author(s)
  竹内理
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Unexpected role of atypical cyclin in mediating macrophage functionality via metabolic regulation2021
- Author(s)
  Yee Kien Chong, Sarang Tartey, Osamu Takeuchi
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] mRNA分解による免疫制御と疾患2021
- Author(s)
  竹内理
- Organizer
  第36回 Wakoワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulating the expression of Regnase-1 by antisense oligonucleoties to counteract inflammatory diseases2021
- Author(s)
  Ka Man Tse, Takashi Mino, Takuya Uehata, Keiko Yasuda, Masanori Yoshinaga, Osamu Takeuchi
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Lymphoid-myeloid cell fateLymphoid-Myeloid cell fate determination by endoribonucleases Regnase-1 and -32021
- Author(s)
  Takuya Uehata, Shinnosuke Yamada, Masaki Miyazaki, Amir Giladi, Alexis Vandenbon, Ido Amit, Hiroshi Kawamoto, Osamu Takeuchi
- Organizer
  MMCB2020+1
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulating the expressions of Regnase-1 by stem-loop-targeting-antisense oligonucleotides to counteract inflammatory diseases2021
- Author(s)
  Ka Man Tse, Xiaotong Cui, Alexis Vandenbon, Takashi Mino, Takuya Uehata, Keiko Yasuda, Ayuko Sato, Tohru Tsujimura, Fabian Hia, Masanori Yoshinaga, Osamu Takeuchi
- Organizer
  第44回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulation of Regnase-1 mRNA stability by morpholino-based antisense oligonucleotides alleviates inflammatory responses in pulmonary and autoimmune diseases2021
- Author(s)
  Ka Man Tse, Xiaotong Cui, Alexis Vandenbon, Keiko Yasuda, Takuya Uehata, Ayuko Sato, Tohru Tsujimura, Takashi Mino, Masanori Yoshinaga, Tatsusada Okuno, Yoshinari Nakatsuka, Osamu Takeuchi
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1/-3-Nfkbiz制御軸が造血幹細胞における細胞分化の方向性を調節する2021
- Author(s)
  Takuya Uehata, Daisuke Ori, Masaki Miyazaki, Amir Giladi, Hiroshi Kawamoto, Ido Amit, Osamu Takeuchi
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Post-transcriptional regulation of innate immunity by Regnase-12021
- Author(s)
  Osamu Takeuchi
- Organizer
  The 27th International Symposium on Molecular Cell Biology of Macrophages
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Deciphering the role of Regnase-1 in the pathophysiology of pulmonary arterial hypertension2021
- Author(s)
  Ai Yaku, Yusuke Manabe, Osamu Takeuchi
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulation of Regnase-1 mRNA stability alleviates inflammatory responses in diseased models2020
- Author(s)
  Tse, K.M., Cui, X., Uehata, T., Takeuchi, O.
- Organizer
  RNA2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1による免疫調節機構2020
- Author(s)
  竹内理
- Organizer
  第7回免疫セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Manipulation of Regnase-1 mRNA stability alleviates inflammatory responses in diseased models2020
- Author(s)
  Tse, K.M., Cui, X., Uehata, T., Takeuchi, O
- Organizer
  MBSJ2020
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Immune regulation by translation-dependent mRNA decay2020
- Author(s)
  Osamu Takeuchi
- Organizer
  MBSJ2020
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Codon Bias Confers Stability to mRNAs in Humans, The 25th Annual Meeting of the RNA Society2020
- Author(s)
  Hia, F., Yang, S.F., Shichino, Y., Yoshinaga, M., Murakawa, Y., Vandenbon, A., Fukao, A., Fujiwara, T., Landthaler, M., Natsume, T., Adachi, S., Iwasaki, S., Takeuchi, O.
- Organizer
  RNA2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20F20115
[Presentation] Regulatory mechanisms of innate immune responses2020
- Author(s)
  Osamu Takeuchi
- Organizer
  FIMSA Immunology course-2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Codon Bias Confers Stability to mRNAs in Humans, The 25th Annual Meeting of the RNA Society2020
- Author(s)
  Hia, F., Yang, S.F., Shichino, Y., Yoshinaga, M., Murakawa, Y., Vandenbon, A., Fukao, A., Fujiwara, T., Landthaler, M., Natsume, T., Adachi, S., Iwasaki, S., Takeuchi, O.
- Organizer
  RNA2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] LYMPHOID-MYELOID CELL FATE DETERMINATION BY ENDORIBONUCLEASES REGNASE-1 AND -32020
- Author(s)
  Takuya, U., Yamada, S., Miyazaki, M., Giladi, A., Vandenbon, A., Amit, I., Kawamoto, H., Takeuchi, O.
- Organizer
  8th Annual Meeting of the International Cytokine & Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] RNA代謝による自然免疫応答の惹起と制御2020
- Author(s)
  竹内理
- Organizer
  日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] RNA分解による免疫応答の制御機構2020
- Author(s)
  竹内理
- Organizer
  2020年度東京大学医科学研究所国際共同利用・共同研究拠点成果報告会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Control of Immune Responses via RNA Degradation2019
- Author(s)
  Osamu Takeuchi
- Organizer
  The Polish-Japanese Meeting on RNA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] RNA分解による免疫細胞の制御機構2019
- Author(s)
  竹内理
- Organizer
  第8回さきがけ「RNAと生体機能」研究会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Ribonucleases Regnase-1 and Regnase-3 have a critical role in cotrolling transcriptome biases in LMPP to ensure lymphopoiesis.2019
- Author(s)
  Shinnosuke Yamada, Takuya Uehata, Osamu Takeuchi
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regulation of immune responses by RNA degradation2019
- Author(s)
  Osamu Takeuchi
- Organizer
  The 18th Awaji International Forum on Infection and Immunity
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] ヒトにおけるコドンバイアスによるmRNA安定性制御2019
- Author(s)
  竹内理
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] RNA分解を介した免疫制御機構2019
- Author(s)
  竹内理
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Endonucleases Regnase-1 and Regnase-3 regulate transcriptome biases to ensure lymphopoiesis.2019
- Author(s)
  Takuya Uehata, Osamu Takeuchi
- Organizer
  CiRA 2019 International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical roles of endonucleases Regnase-1 and Regnase-3 in early lymphopoiesis.2019
- Author(s)
  Takuya Uehata, Osamu Takeuchi
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Codon Bias Confers Stability to mRNAs via ILF2 in Humans2019
- Author(s)
  Hia, F., Takeuchi, O
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 免疫細胞制御における翻訳とmRNA分解の連関2019
- Author(s)
  竹内理
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Unwinding of stem-loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs.2019
- Author(s)
  Takashi Mino, Osamu Takeuchi
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] A型肝炎ウイルスIRES依存的翻訳は肝臓特異的因子により活性化される2018
- Author(s)
  貞廣暁利，深尾亜喜良，小坂実央，滝沢直己，船上仁範，竹内理，Duncan, K.E.，藤原俊伸
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Post-transcriptional control of innate immune responses2018
- Author(s)
  Osamu Takeuchi
- Organizer
  Japan-Germany Immunology Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Innate immune Sensing and Regulation2018
- Author(s)
  Osamu Takeuchi
- Organizer
  第66回ウイルス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The role of CyclinJ as a Novel Regulator in Modulating Tumor-associated Macrophage (TAM).2018
- Author(s)
  Chong, Y.K., and Takeuchi, O.
- Organizer
  The 47th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 鉄代謝を制御する転写後調節機構の解明2018
- Author(s)
  吉永正憲，三野享史，Bassik, M. C.，竹内理
- Organizer
  第20回日本RNA学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] dentification of a host RNA binding protein as a novel HIV-1 restriction factor.2018
- Author(s)
  Yamasoba, D., Sato, K., Hotter, D., EReith, E., Koepke, L., Linsenmeyer, R., Standley, D.M., Sauter, D., Koyanagi, Y., and Takeuchi, O.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Retroviruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical roles of endonucleases Regnase-1 and Regnase-3 in early lymphopoiesis2018
- Author(s)
  Takuya Uehata, Shinnosuke Yamada, Masaki Miyazaki, Hiroshi Kawamoto, Osamu Takeuchi
- Organizer
  Keystone Symposia, Transcription and RNA Regulation in Inflammation and Immunity (B1)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] MALT1によるN4BP1の分解は潜伏感染HIV-1の再活性化を促進する2018
- Author(s)
  山岨大智，佐藤佳，小柳義夫，竹内理
- Organizer
  第32回日本エイズ学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The role of CyclinJ in modulating innate immune cells and inflammation.2018
- Author(s)
  Chong, Y.K., Tartey, S, and Takeuchi, O.
- Organizer
  The 25th International Symposium on Molecular Cell Biology of Macrophages.
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Post-transcriptional control of innate immune responses2018
- Author(s)
  Osamu Takeuchi
- Organizer
  Japanese-German Immunology Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04027
[Presentation] mRNA分解による免疫調節機構とその制御2018
- Author(s)
  竹内　理
- Organizer
  日本核酸医薬学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04027
[Presentation] Posttranscriptional control of pro-inflammatory cytokine expression by Regnase-1 and Roquin2018
- Author(s)
  Osamu Takeuchi
- Organizer
  WCP2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04027
[Presentation] Posttranscriptional control of pro-inflammatory cytokine expression by Regnase-1 and Roquin2018
- Author(s)
  Osamu Takeuchi
- Organizer
  WCP2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] 新規RNA分解酵素によるHIV-1感染制御機構の解明2018
- Author(s)
  山岨大智，佐藤佳，小柳義夫，竹内理
- Organizer
  第29回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Critical Roles of an RNase N4BP1 in Anti-HIV-1 Host Defense and its Control by TCR Signaling2018
- Author(s)
  Osamu Takeuchi
- Organizer
  Keystone Symposia, Transcription and RNA Regulation in Inflammation and Immunity (B1)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] mRNA分解を介した免疫制御機構2018
- Author(s)
  竹内理
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] SMG1はRegnase-1経路を介して炎症性mRNAを制御する2018
- Author(s)
  三野享史，岩井紀貴，赤木宏太朗，山下暁朗，竹内理
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1によるmRNA分解を介した免疫制御機構2018
- Author(s)
  竹内理
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] MALT1-mediated cleavage of N4BP1, an antiviral RNase, contributes to the viral reactivation in latently HIV-1 infected cells2018
- Author(s)
  山岨大智，佐藤佳，小柳義夫，竹内理
- Organizer
  第66回ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1は鉄代謝関連のmRNAを分解することで鉄恒常性を維持する2018
- Author(s)
  吉永正憲，三野享史，竹内理
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Regnase-1によるmRNA分解を介した免疫制御機構2018
- Author(s)
  竹内　理
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04027
[Presentation] mRNA分解による免疫調節機構とその制御2018
- Author(s)
  竹内理
- Organizer
  日本核酸医薬学会第4回年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] The ribonuclease Regnase-1 maintains iron homeostasis via the destabilization of iron-regulatory transcripts.2018
- Author(s)
  Yoshinaga, M., Mino, T., and Takeuchi, O.
- Organizer
  RNA2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] RNA分解酵素Regnase-1による鉄代謝制御機構2018
- Author(s)
  竹内理
- Organizer
  第４２回日本鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H05278
[Presentation] Posttranscriptional control of inflammation by an RNase, Regnase-1.2012
- Author(s)
  Takeuchi, O
- Organizer
  IEIIS2012
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Posttranscriptional control of inflammation.2012
- Author(s)
  Takeuchi, O.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Posttranscriptional control of inflammation by an RNase, Regnase-1.2012
- Author(s)
  Takeuchi, O
- Organizer
  19th East Asia Joint Symposium on Biomedical Research
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Posttranscriptional control of inflammation by an RNase, Regnase-1.2012
- Author(s)
  Takeuchi, O
- Organizer
  19th East Asia Joint Symposium on Biomedical Research
- Place of Presentation
  Seoul, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Posttranscriptional control of inflammation by an Rnase, Regnase-12012
- Author(s)
  Takeuchi, O
- Organizer
  IEIIS2012
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Recognition of viral infection by innate immunity.2012
- Author(s)
  Takeuchi, O.
- Organizer
  Single Topic Conference “Hepatitis C: Best Practice Based on Science”
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Review Talk: Systems Immunology―最近の動向.2012
- Author(s)
  Takeuchi, O.
- Organizer
  Annual Meeting of Japanese Society for Immunology
- Place of Presentation
  Kobe
- Invited
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Systems Immunology-最近の動向2012
- Author(s)
  Takeuchi, O.
- Organizer
  Annual Meeting of Japanese Society for Immunology
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Recognition of viral infection by innate immunity2012
- Author(s)
  Takeuchi, O
- Organizer
  Single Topic Conference "Hepatitis C: Best Practice Based on Science"
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] RNA分解酵素Regnase-1による自然免疫制御2012
- Author(s)
  竹内理
- Organizer
  日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Posttranscriptional control of inflammation2012
- Author(s)
  Takeuchi, O
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] RNA分解調節による炎症制御メカニズム2011
- Author(s)
  竹内理
- Organizer
  第75回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  静岡県立大学(静岡)(招待講演)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] 自然免疫応答調節メカニズム2011
- Author(s)
  竹内理
- Organizer
  第19回肺リモデリング研究会
- Place of Presentation
  東京ステーションコンファレンス(東京)(招待講演)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Control of inflammation by Toll-like receptor-inducible genes2011
- Author(s)
  Osamu Takeuchi
- Organizer
  Avison Biomedical Symposium
- Place of Presentation
  Seoul (Korea)(招待講演)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Regulation of inflammation by Toll-like receptor-inducible genes2011
- Author(s)
  Osamu Takeuchi
- Organizer
  International Symposium : Towards comprehensive understanding of Immune Dynamism
- Place of Presentation
  千里阪急ホテル(大阪)
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Rapid degradation of Zc3h12a to TLR/IL-1R stimulation regulates inflammatory gene expression2011
- Author(s)
  Osamu Takeuchi
- Organizer
  Toll2011
- Place of Presentation
  Riva del Garda Congress Center(Italy)
- Year and Date
  2011-05-07
- Data Source
  KAKENHI-PROJECT-20002008
[Presentation] Rapid degradation of Zc3h12a to TLR/IL-1R stimulation regulates inflammatory gene expression2011
- Author(s)
  Osamu Takeuchi
- Organizer
  Toll2011
- Place of Presentation
  Riva del Garda, Italy
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Zc3h12a, an RNase promoting Interleukin 6 mRNA decay, undergoes posttranscriptional modification to pathogenic stimuli2011
- Author(s)
  Osamu Takeuchi
- Organizer
  RNA2011
- Place of Presentation
  国立京都国際会館(京都)(招待講演)
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Control of inflammation by Toll-like receptor-inducible genes2011
- Author(s)
  Osamu Takeuchi
- Organizer
  International Symposium on Cell Dynamics and Bioimaging
- Place of Presentation
  GIST, Gwangju (Korea)(招待講演)
- Year and Date
  2011-02-23
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Role of Zc3h12c in regulating inflammatory responses in macrophages2010
- Author(s)
  Osamu Takeuchi
- Organizer
  International Congress of Immunology
- Place of Presentation
  神戸ポートピアホテル(兵庫)
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] 自然免疫たよる炎症制御機構2010
- Author(s)
  竹内理
- Organizer
  Molecular Cardiovascular Conference II
- Place of Presentation
  キロロホテルピアノ(北海道)(招待講演)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] RIG-Iファミリーによるウイルス感染認識メカニズム2010
- Author(s)
  竹内理
- Organizer
  第58回日本ウイルス学会
- Place of Presentation
  あわぎんホール(徳島)(招待講演)
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Mechanisms of innate immune recognition to virus infection2010
- Author(s)
  Osamu Takeuchi
- Organizer
  17th International Meeting on Hepatitis C Virus and Related Viruses
- Place of Presentation
  パシフィコ横浜(神奈川)(招待講演)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22689016
[Presentation] Zc3h12a is an RNase promoting Interleukin 6 mRNA decay and regulates immune responses.2010
- Author(s)
  Osamu Takeuchi
- Organizer
  Gordon Conference
- Place of Presentation
  Salve Regina University (USA)(招待講演)
- Data Source
  KAKENHI-PROJECT-22689016

1. CHONG YEE KIEN

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. AKIRA Shizuo (50192919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 27 results
3. KAWAI Taro (50456935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. SAITOH Tatsuya (60456936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. SATOH Takashi (60619716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
6. MASUDA Kazuya (70722544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KISHIMOTO Tadamitsu (10093402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 植畑拓也 (50785970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
9. 三野享史 (60646149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
10. HIA FABIAN

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. Yoshinaga Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
12. TIN Kazuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 今見考志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 村川泰裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 野田岳志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 山下暁朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 小井川浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 真嶋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 堀雄一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 榛葉旭恒

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 藤原俊伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takeuchi Osamu 竹内 理

TAKEUCHI Osamu 竹内 理

竹内 理 タケウチ オサム

Research Projects

Research Products

Co-Researchers

内在性レトロウイルスに起因する撹乱RNAの安定性制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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抗腫瘍T細胞応答を調節する転写後制御機構の解析Principal Investigator

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mRNA結合タンパク質による免疫制御機構の解明Principal Investigator

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抗腫瘍T細胞応答を調節する転写後制御機構の解析Principal Investigator

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コドンに隠された暗号の解明：ヒトコドン最適化制御による治療戦略Principal Investigator

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Analysis of immune regulatory mechanisms mediated by mRNA metabolismPrincipal Investigator

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Control of immune responses via spatiotemporal regulation of mRNA decayPrincipal Investigator

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The pathogenic role of Arid5a in infection and autoimmunity.

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Analysis of the mechanisms of an RNase, Zc3h12a-mediated immune regulation.Principal Investigator

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Comprehensive study of innate immunity

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自然免疫系によるウイルス特異的分子パターン認識機構の解析Principal Investigator

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[Book] RNA Damage and Repair2021

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[Book] RNA Damage and Repair (The Role of Ribonucleases in RNA Damage, Inactivation and Degradation)2021

Author(s)

Takeuchi Osamu 竹内理

TAKEUCHI Osamu 竹内理

竹内理タケウチオサム