kojima hiroyuki 小島弘幸

… Alternative Names

KOJIMA Hiroyuki 小島弘幸

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Researcher Number	10414286
External Links
Affiliation (Current)	2025: 北海道医療大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 北海道医療大学, 薬学部, 教授 2018: 北海道立衛生研究所, その他部局等, 部長等 2017: 北海道立衛生研究所, その他部局等, 主幹 2017: 北海道立衛生研究所, 生活科学部, 部長 2015 – 2016: 北海道立衛生研究所, 生活科学部, 主幹 … More 2015: 北海道立衛生研究所, 食品科学部・薬品安全グループ, 主幹 2013 – 2015: 北海道立衛生研究所, 食品科学部, 主幹 2012: 北海道立衛生研究所, その他部局等, 研究員 2012: 北海道立衛生研究所, 理化学部, 主幹 2012: 北海道道立衛生研究所 2011: 北海道立衛生研究所, 理化学部, 主査(有害化学物質) 2011: 日米薬科大学, 北海道立衛生研究所, 研究主査 2010: 北海道立衛生研究所, 研究主査 2007 – 2010: Hokkaido Institute of Public Health, 健康科学部, 研究主査 2005 – 2007: Hokkaido Institute of Public Health, researcher, 研究職員 Less
Review Section/Research Field	Principal Investigator Hygiene / Basic Section 63040:Environmental impact assessment-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health Except Principal Investigator Hygiene / Public health/Health science / Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Basic Section 38050:Food sciences-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 環境化学物質 / 核内受容体 / AhR / 遺伝子発現 / 免疫毒性 / レポーターアッセイ / Th17 / ROR / レポーター遺伝子アッセイ / 化学物質 … More / 環境保健 / ヒト血液 / トリプトファン代謝物 / 炎症性腸疾患 / ヒト血清 / 疫学 / AhR活性 / 海洋汚染物質 / 核内受容体Nr4a / Foxp3 / Nr4a / 制御性T細胞 / 制御性Ｔ細胞 / ベンゾトリアゾール系UV吸収剤 / アリルハイドロカーボン受容体 / マイクロプラスチック / 環境 / 可塑剤 / 難燃剤 / ビスフェノール類 / ポリ塩化ビフェニル類 / 複合曝露 / 免疫 / 複合曝露影響 / ダイオキシン / 自己免疫疾患 / IL17 / IL-17 / アンドロゲン受容体 / エストロゲン受容体 / 化学物質過敏症 / 室内空気 / シックハウス症候群 … More Except Principal Investigator 核内受容体 / 内分泌かく乱 / 内分泌かく乱作用 / バイオマーカー / 遺伝子発現 / 環境化学物質 / multiple chemical sensitivity / mRNA / DNAマイクロアレイ解析 / 多種類化学物質過敏症 / シックハウス症候群 / 低出生体重 / 母子保健 / 喘息 / 網羅的遺伝子発現 / フタル酸エステル類 / 疫学研究 / 環境疫学 / ゴミ埋立地浸出水 / 医薬品 / 高感度化 / エストロゲン受容体 / BPA代替物質 / ごみ埋立処分場浸出水 / ビスフェノール化合物 / バイオアッセイ / 一斉分析 / プラスチック添加剤 / 柱状堆積物 / プラスチック / 添加剤 / 紫外線吸収剤 / 内分泌攪乱化学物質 / ビスフェノールA / ノニルフェノール / マイクロプラスチック / 環境ホルモン / 浸出水 / 廃棄物埋立処分場 / ベンゾトリアゾール / BPA / ビスフェノール / 膵臓癌 / がん予防 / 癌幹細胞 / 癌化学予防 / 膵癌 / フコキサンチノール / 膵臓がん / 腫瘍微小環境 / がん化学予防 / 海藻 / フコキサンチン / カロテノイド / 第二次性徴 / 内分泌かく乱物質 / 遺伝子発現解析 / 生殖ホルモン / 細胞アッセイ系 / 遺伝子多型 / 出生コーホート / 有機フッ素化合物 / 衛生 / 環境 / フィラグリン / 酸化ストレスマーカー / ハウスダスト / 遺伝子 / アトピー性皮膚炎 / experimental animars / patients / formaldehyde / DNA micro allay analysis / immunological test / sick building syndrome / 実験動物 / 患者 / ホルムアルデヒド / 免疫学的検査 / bio chemical analysis / biomarker / marker gene / DNA micro alley analysis / peripheral blood mono nucleocyte / sick house syndrome / 生化学的検査 / 生体因子産物 / マーカー遺伝子 / 末梢血単核球 / 食事パターン / マイクロRNA(miRNA) / 発育 / 一塩基多型(SNP) / 成長軌跡 / DOHaD / 小児肥満 / プロテインジスルフィドイソメラーゼ / 核内レセプター / 甲状腺ホルモン撹乱 / プロテインジスルフィッドイソメラーゼ / 甲状腺ホルモン / 水酸化代謝物 / 代謝的活性化 / 内分泌撹乱 / ブロム化難燃剤 / サイトカイン / 早産 / 農薬 / 不育症 / 化学物質 / 遺伝要因 / エピジェネティック要因 Less

Measurement of AhR activity in human serum using a cell-besed assay and its application for epidemiological studyPrincipal Investigator
- Principal Investigator
  
  小島弘幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63040:Environmental impact assessment-related
- Research Institution
  Health Sciences University of Hokkaido
Adverse health effects of environmental chemical exposure: elucidation of mechanisms via human and animal studies
- Principal Investigator
  
  池田敦子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hokkaido University
Elucidation of molecular network-regulating mechanisms on pancreatic tumor microenvironment suppression by fucoxanthin
- Principal Investigator
  
  TERASAKI Masaru
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Health Sciences University of Hokkaido
Sources and behaviors of broad-spectrum phenolic endocrine distrusting chemicals (EDCs) and historical trends of their pollution
- Principal Investigator
  
  高田秀重
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Tokyo University of Agriculture and Technology
Effects of microplastic-derived chemicals on functions of regulatory T cells via nuclear receptor Nr4a.Principal Investigator
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Health Sciences University of Hokkaido
Perfluorinated alkyl substances exposure and onset of puberty - birth cohort and in vitro studies
- Principal Investigator
  
  Ikeda Atsuko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Hokkaido University
Effects of chemical mixtures contained in foods on immune response via nuclear receptors.Principal Investigator
- Principal Investigator
  
  Kojima Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Hokkaido Institute of Public Health
FLG variance and environmnetal chemical exposure to atopic dermatitis among school children
- Principal Investigator
  
  Atsuko Araki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene and public health
- Research Institution
  Hokkaido University
Interaction among fetal environment, genome and epigenome and growth trajectory after birth: verification of DOHaD theory
- Principal Investigator
  
  Sata Fumihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Tokyo Medical and Dental University
  National Institute of Public Health
Effects of environmental chemicals on Th17 cells differenciation via aryl hydrocarbon receptorPrincipal Investigator
- Principal Investigator
  
  KOJIMA HIROYUKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health
Determination of targets for thyroid hormone disruption by brominated flame retardants
- Principal Investigator
  
  KITAMURA Shigeyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nihon Pharmaceutical University
Effects of environmental chemicals on differentiation of helper-T 17 cells via retinoic acid receptor-related orphan receptorsPrincipal Investigator
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health
化学物質に対する胎児・小児の脆弱性に係わる遺伝・エピジェネティック要因の解明
- Principal Investigator
  
  Sata Fumihiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  National Institute of Public Health
Effects of Indoor Air Chemicals on Transcriptional Activities via Nuclear Receptors and Dioxin ReceptorPrincipal Investigator
- Principal Investigator
  
  KOJIMA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Hokkaido Institute of Public Health
Animal experiment and clinical research on the immunological involvement in pathological formation of sick building symptoms
- Principal Investigator
  
  YOSHIDA Takahiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Asahikawa Medical College
Developmental research of biochemical test based on the molecular biological analysis of sick house syndrome
- Principal Investigator
  
  YOSHIDA Takahiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Asahikawa Medical College

[Journal Article] Immunoregulatory Effects of Elemental Diet and Its Ingredient, Tryptophan, via Activation of the Aryl Hydrocarbon Receptor in Mice2024
- Author(s)
  Kubota Atsuhito、Imai Shungo、Aoyagi Ryoichi、Murase Wataru、Terasaki Masaru、Sugawara Mitsuru、Takekuma Yoh、Kojima Hiroyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 6 Pages: 3448-3448
- DOI
  10.3390/ijms25063448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K11454, KAKENHI-PROJECT-21K14821
[Journal Article] Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays2023
- Author(s)
  Murase Wataru、Kubota Atsuhito、Ikeda-Araki Atsuko、Terasaki Masaru、Nakagawa Koji、Shizu Ryota、Yoshinari Kouichi、Kojima Hiroyuki
- Journal Title
  
  Toxicology
  
  Volume: 494 Pages: 153577-153577
- DOI
  10.1016/j.tox.2023.153577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K11454, KAKENHI-PROJECT-21H04843
[Journal Article] Requirement of CLIC4 Expression in Human Colorectal Cancer Cells for Sensitivity to Growth Inhibition by Fucoxanthinol2022
- Author(s)
  YOKOYAMA REO、KUSHIBIKI AYUMI、YAMADA SHIORI、KUBOTA ATSUHITO、KOJIMA HIROYUKI、OHTA TOHRU、HAMADA JUNICHI、MAEDA HAYATO、MUTOH MICHIHIRO、TERASAKI MASARU
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 19 Issue: 4 Pages: 428-444
- DOI
  10.21873/cgp.20330
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05879
[Journal Article] A Biscuit Containing Fucoxanthin Prevents Colorectal Carcinogenesis in Mice2022
- Author(s)
  Terasaki Masaru、Murase Wataru、Kamakura Yukino、Kawakami Serina、Kubota Atsuhito、Kojima Hiroyuki、Ohta Tohru、Tanaka Takuji、Maeda Hayato、Miyashita Kazuo、Mutoh Michihiro
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 74 Issue: 10 Pages: 3651-3661
- DOI
  10.1080/01635581.2022.2086703
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05879
[Journal Article] Effects of benzotriazole UV stabilizers, UV-PS and UV-P, on the differentiation of splenic regulatory T cells via aryl hydrocarbon receptor2022
- Author(s)
  Kubota Atsuhito、Terasaki Masaru、Sakuragi Yuuta、Muromoto Ryuta、Ikeda-Araki Atsuko、Takada Hideshige、Kojima Hiroyuki
- Journal Title
  
  Ecotoxicology and Environmental Safety
  
  Volume: 238 Pages: 113549-113549
- DOI
  10.1016/j.ecoenv.2022.113549
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-21K14821, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin2022
- Author(s)
  Terasaki Masaru、Ono Shion、Hashimoto Saki、Kubota Atsuhito、Kojima Hiroyuki、Ohta Tohru、Tanaka Takuji、Maeda Hayato、Miyashita Kazuo、Mutoh Michihiro
- Journal Title
  
  The Journal of Nutritional Biochemistry
  
  Volume: 99 Pages: 108871-108871
- DOI
  10.1016/j.jnutbio.2021.108871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Fucoxanthinol Promotes Apoptosis in MCF-7 and MDA-MB-231 Cells by Attenuating Laminins?Integrins Axis2022
- Author(s)
  Yasuda Ayaka、Wagatsuma Momoka、Murase Wataru、Kubota Atsuhito、Kojima Hiroyuki、Ohta Tohru、Hamada Junichi、Maeda Hayato、Terasaki Masaru
- Journal Title
  
  Onco
  
  Volume: 2 Issue: 3 Pages: 145-163
- DOI
  10.3390/onco2030010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05471, KAKENHI-PROJECT-20K05879
[Journal Article] 5-Aminosalicylic Acid, A Weak Agonist for Aryl Hydrocarbon Receptor That Induces Splenic Regulatory T Cells2021
- Author(s)
  Kubota Atsuhito、Terasaki Masaru、Takai Rie、Kobayashi Masaki、Muromoto Ryuta、Kojima Hiroyuki
- Journal Title
  
  Pharmacology
  
  Volume: 107 Issue: 1-2 Pages: 28-34
- DOI
  10.1159/000520404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879, KAKENHI-PROJECT-21K14821
[Journal Article] An analytical survey of benzotriazole UV stabilizers in plastic products and their endocrine-disrupting potential via human estrogen and androgen receptors2021
- Author(s)
  Sakuragi Yuuta、Takada Hideshige、Sato Hiroya、Kubota Atsuhito、Terasaki Masaru、Takeuchi Shinji、Ikeda-Araki Atsuko、Watanabe Yoko、Kitamura Shigeyuki、Kojima Hiroyuki
- Journal Title
  
  Science of The Total Environment
  
  Volume: 800 Pages: 149374-149374
- DOI
  10.1016/j.scitotenv.2021.149374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain “gatekeeper” function2021
- Author(s)
  Takeda Fuyo、Oda Masako、Terasaki Masaru、Ichimura Yuichi、Kojima Hiroyuki、Saitoh Hiroshi
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 423 Pages: 115570-115570
- DOI
  10.1016/j.taap.2021.115570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843
[Journal Article] Fucoxanthin Prevents Pancreatic Tumorigenesis in C57BL/6J Mice That Received Allogenic and Orthotopic Transplants of Cancer Cells2021
- Author(s)
  Murase Wataru、Kamakura Yukino、Kawakami Serina、Yasuda Ayaka、Wagatsuma Momoka、Kubota Atsuhito、Kojima Hiroyuki、Ohta Tohru、Takahashi Mami、Mutoh Michihiro、Tanaka Takuji、Maeda Hayato、Miyashita Kazuo、Terasaki Masaru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 24 Pages: 13620-13620
- DOI
  10.3390/ijms222413620
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-20K05879
[Journal Article] A fucoxanthinol induces apoptosis in a pancreatic 　intraepithelial neoplasia cells.2021
- Author(s)
  Terasaki, M., Takuya Inoue, T., Murase, W., Atsuhito Kubota, A., Kojma, H., Kojoma, M., Ohta, T., Maeda, H., Miyashita, K., Mutoh, M., Takahashi, M.
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 18 Issue: 2 Pages: 133-146
- DOI
  10.21873/cgp.20248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07081, KAKENHI-PROJECT-20K05879
[Journal Article] Detection of Cells Displaying High Expression of CLIC4 in Tumor Tissue of Patients With Colorectal Cancer2021
- Author(s)
  YOKOYAMA REO、KUBOTA ATSUHITO、KOJIMA HIROYUKI、TANAKA TAKUJI、MUTOH MICHIHIRO、TERASAKI MASARU
- Journal Title
  
  In Vivo
  
  Volume: 35 Issue: 6 Pages: 3165-3173
- DOI
  10.21873/invivo.12611
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells2021
- Author(s)
  Terasaki M, Takahashi S, Nishimura R, Kubota A, Kojima H, Ohta T, Hamada J, Kuramitsu Y, Maeda H, Miyashita K, Takahashi M, Mutoh M
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 16 Issue: 1 Pages: 1-16
- DOI
  10.1080/01635581.2020.1863994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05879
[Journal Article] Fucoxanthin and Colorectal Cancer Prevention2021
- Author(s)
  Terasaki Masaru、Kubota Atsuhito、Kojima Hiroyuki、Maeda Hayato、Miyashita Kazuo、Kawagoe Chikara、Mutoh Michihiro、Tanaka Takuji
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 10 Pages: 2379-2379
- DOI
  10.3390/cancers13102379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Fucoxanthin Prevents Colorectal Cancer Development in Dextran Sodium Sulfate-treated Apc Min/+ Mice2021
- Author(s)
  Terasaki M, Hamoya T, Kubota A, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 3 Pages: 1299-1305
- DOI
  10.21873/anticanres.14887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05879
[Journal Article] Downregulated expression of organic anion transporting polypeptide (Oatp) 2b1 in the small intestine of rats with acute kidney injury2021
- Author(s)
  Takeda Fuyo、Oda Masako、Terasaki Masaru、Kubota Atsuhito、Asada Keita、Ichimura Yuichi、Kojima Hiroyuki、Saitoh Hiroshi
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 40 Pages: 100411-100411
- DOI
  10.1016/j.dmpk.2021.100411
- NAID
  210000166019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-21H04843, KAKENHI-PROJECT-20K05879
[Journal Article] Effects of CLIC4 on Fucoxanthinol-Induced Apoptosis in Human Colorectal Cancer Cells2020
- Author(s)
  Yokoyama Reo、Kojima Hiroyuki、Takai Rie、Ohta Tohru、Maeda Hayato、Miyashita Kazuo、Mutoh Michihiro、Terasaki Masaru
- Journal Title
  
  Nutrition and Cancer
  
  Volume: 73 Issue: 5 Pages: 889-898
- DOI
  10.1080/01635581.2020.1779760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-18H03035
[Journal Article] Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice2020
- Author(s)
  Terasaki Masaru、Uehara Osamu、Ogasa Shinya、Sano Taishi、Kubota Atsuhito、Kojima Hiroyuki、Tanaka Takuji、Maeda Hayato、Miyashita Kazuo、Mutoh Michihiro
- Journal Title
  
  Carcinogenesis
  
  Volume: 42 Issue: 2 Pages: 210-219
- DOI
  10.1093/carcin/bgaa100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-18H03035
[Journal Article] Continuity of Tumor Microenvironmental Suppression in AOM/DSS Mice by Fucoxanthin May Be Able to Track With Salivary Glycine2020
- Author(s)
  TERASAKI MASARU、KIMURA RYOTA、KUBOTA ATSUHITO、KOJIMA HIROYUKI、TANAKA TAKUJI、MAEDA HAYATO、MIYASHITA KAZUO、MUTOH MICHIHIRO
- Journal Title
  
  In Vivo
  
  Volume: 34 Issue: 6 Pages: 3205-3215
- DOI
  10.21873/invivo.12156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-18H03035
[Journal Article] Dietary fucoxanthin induces anoikis in colorectal adenocarcinoma through suppressing integrin signaling in a murine colorectal cancer model.2020
- Author(s)
  3.Terasaki M, Ikuta M, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M.
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 1 Pages: 90-90
- DOI
  10.3390/jcm9010090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-18H03035
[Journal Article] Inhibitory effects of organophosphate esters on carboxylesterase activity of rat liver microsomes2020
- Author(s)
  Tsugoshi Yukie、Watanabe Yoko、Tanikawa Yuka、Inoue Chika、Sugihara Kazumi、Kojima Hiroyuki、Kitamura Shigeyuki
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 327 Pages: 109148-109148
- DOI
  10.1016/j.cbi.2020.109148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-18H03035
[Journal Article] The mixture effects of bisphenol derivatives on estrogen receptor and androgen receptor.2020
- Author(s)
  Park C, Song H, Choi J, Sim S, Kojima H, Park M, Iida M, Lee YJ.
- Journal Title
  
  Environmental Pollution
  
  Volume: 260 Pages: 114036-114036
- DOI
  10.1016/j.envpol.2020.114036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-18H03035
[Journal Article] Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An in Silico and in Vitro Study2020
- Author(s)
  Kenda Masa、Karas Kuzelicki Natasa、Iida Mitsuru、Kojima Hiroyuki、Sollner Dolenc Marija
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 128 Issue: 10 Pages: 107005-107005
- DOI
  10.1289/ehp6596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-20H00627, KAKENHI-PROJECT-18H03035
[Journal Article] Distribution of 58 semi-volatile organic chemicals in the gas phase and three particle sizes in indoor air and house dust in residential buildings during the hot season in Japan2019
- Author(s)
  3.Takeuchi S, Tanaka-Kagawa T, Saito I, Kojima H, Jinno H
- Journal Title
  
  BPB reports
  
  Volume: 2(6) Pages: 91-98
- NAID
  130007940489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03035
[Journal Article] Comparative study of the effect of 17 parabens on PXR-, CAR- and PPARalpha-mediated transcriptional activation.2019
- Author(s)
  1.Fujino C, Watanabe Y, Sanoh S, Hattori S, Nakajima H, Uramaru N, Kojima H, Yoshinari K, Ohta S, Kitamura S.
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 133 Pages: 110792-110792
- DOI
  10.1016/j.fct.2019.110792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-17K15493
[Journal Article] Effects of benzotriazole ultraviolet stabilizers on rat PXR, CAR and PPARα transcriptional activities2019
- Author(s)
  Watanabe Yoko、Hattori Shoko、Fujino Chieri、Tachibana Ken、Kojima Hiroyuki、Yoshinari Kouichi、Kitamura Shigeyuki
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 6 Issue: 2 Pages: 57-63
- DOI
  10.2131/fts.6.57
- NAID
  130007616171
- ISSN
  2189-115X
- Year and Date
  2019-03-19
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03035
[Journal Article] Activation of PXR, CAR and PPARalpha by pyrethroid pesticides and effect of the metabolism by rat liver microsomes.2019
- Author(s)
  2.Fujino C, Watanabe Y, Sanoh S, Nakajima H, Uramaru N, Kojima H, Yoshinari K, Ohta S, Kitamura S.
- Journal Title
  
  Heliyon
  
  Volume: 5 Issue: 9 Pages: e02466-e02466
- DOI
  10.1016/j.heliyon.2019.e02466
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10611, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-17K15493
[Journal Article] Profiling of bisphenol A and eight its analogues on transcriptional activity via human nuclear receptors2019
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Seigo Sanoh, Katsuhiro Okuda, Shigeyuki Kitamura, Naoto Uramaru, Kazumi Sugihara, Kouichi Yoshinari
- Journal Title
  
  Toxicology, 413(2),48-55,
  
  Volume: 413 Pages: 48-55
- DOI
  10.1016/j.tox.2018.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08401, KAKENHI-PROJECT-17K15493, KAKENHI-PROJECT-18H03035, KAKENHI-PROJECT-16K00559
[Journal Article] 危険ドラッグ検査の化学分析を補完する薬物受容体アッセイ及び植物片DNA解析の有用性評価2018
- Author(s)
  武内伸治、高橋正幸、藤本啓、佐藤正幸、小島弘幸
- Journal Title
  
  北海道公衆衛生学雑誌
  
  Volume: 32 Pages: 85-91
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03035
[Journal Article] Improved androgen specificity of AR-EcoScreen by CRISPR based glucocorticoid receptor knockout2017
- Author(s)
  Zwart Nick、Andringa Dave、de Leeuw Willem-Jan、Kojima Hiroyuki、Iida Mitsuru、Houtman Corine J.、de Boer Jacob、Kool Jeroen、Lamoree Marja H.、Hamers Timo
- Journal Title
  
  Toxicology in Vitro
  
  Volume: 45 Pages: 1-9
- DOI
  10.1016/j.tiv.2017.08.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791
[Journal Article] 肝細胞肥大の毒性学的特徴の解明に向けた農薬のラット反復投与毒性試験結果のデータベース構築2017
- Author(s)
  増田茜、増田雅美、川野拓歩、橘内陽子、中山晴香、中島宏之、小島弘幸、北村繁幸、浦丸直人、保坂卓臣、佐々木崇光、吉成浩一
- Journal Title
  
  薬学雑誌
  
  Volume: 137 Pages: 611-622
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08791
[Journal Article] Effects of unintentional PCBs in pigments and chemical products on transcriptional activity via aryl hydrocarbon and nuclear hormone receptors2017
- Author(s)
  Shinji Takeuchi, Katsunori Anezaki, Hiroyuki Kojima
- Journal Title
  
  Environmental Pollution
  
  Volume: 227 Pages: 306-313
- DOI
  10.1016/j.envpol.2017.04.059
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26740032, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791
[Journal Article] Biochanin A enhances RORγ activity through STAT3-mediated recruitment of NCOA12017
- Author(s)
  Takahashi Miki、Muromoto Ryuta、Kojima Hiroyuki、Takeuchi Shinji、Kitai Yuichi、Kashiwakura Jun-ichi、Matsuda Tadashi
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 489 Issue: 4 Pages: 503-508
- DOI
  10.1016/j.bbrc.2017.05.181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08263, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791
[Journal Article] 肝細胞肥大の毒性学的特徴の解明に向けた農薬のラット反復投与毒性試験結果のデータベース構築2017
- Author(s)
  増田茜,増田雅美,川野拓歩,橘内陽子,中山晴香,中島宏之,小島弘幸,北村繁幸,浦丸直人,保坂卓臣,佐々木崇光,吉成浩一
- Journal Title
  
  薬学雑誌
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04780
[Journal Article] Activation of nuclear receptor CAR by an environmental pollutant perfluorooctanoic acid.2017
- Author(s)
  Abe, T., Takahashi, M., Kano, M., Amaike, Y., Ishii, C., Maeda, K., Kudoh, Y., Morishita, T., Hosaka, T., Sasaki, T., Kodama, S., Matsuzawa, A., Kojima, H., Yoshinari, K.
- Journal Title
  
  Arch. Toxicol.
  
  Volume: 印刷中 Issue: 6 Pages: 2365-2374
- DOI
  10.1007/s00204-016-1888-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01168, KAKENHI-PUBLICLY-15H01391, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-26293011, KAKENHI-PROJECT-25460195, KAKENHI-PROJECT-15K08791, KAKENHI-PUBLICLY-17H05518, KAKENHI-PROJECT-16K15146
[Journal Article] Differential determination of plasticizers and organophosphorus flame retardants in residential indoor air in Japan.2016
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Ikue Saito, Hiroyuki Kojima, Kazuo Jin, Masayuki Satoh, Satoshi Kobayashi, Hideto Jinno
- Journal Title
  
  Environ. Sci. Pollut. Res.
  
  Volume: in press Issue: 8 Pages: 1-7
- DOI
  10.1007/s11356-015-4858-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-24390172
[Journal Article] Metabolism of methiocarb and carbaryl by rat and human livers and plasma, and effect on their PXR, CAR and PPARα activities2016
- Author(s)
  Chieri Fujino, Yuki Tamura, Satoko Tange, Hiroyuki Nakajima, Seigo Sanoh, Yoko Watanabe, Naoto Uramaru, Hiroyuki Kojima, Kouichi Yoshinari, Shigeru Ohta, Shigeyuki Kitamura
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 41 Issue: 5 Pages: 677-691
- DOI
  10.2131/jts.41.677
- NAID
  130005266225
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-16K00559
[Journal Article] Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Nele Van den Eede, Adrian Covaci
- Journal Title
  
  Toxicol. Lett.
  
  Volume: 245 Pages: 31-39
- DOI
  10.1016/j.toxlet.2016.01.004
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780
[Journal Article] A sensitive, rapid and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Shoji F. Nakayama, Takuya Shiozaki
- Journal Title
  
  Environ. Sci. Pollut. Res.
  
  Volume: in press Issue: 8 Pages: 1-7
- DOI
  10.1007/s11356-015-4662-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08791, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-24390172
[Journal Article] Effects of primary metabolites of organophosphate flame retardants on transcriptional activity via human nuclear receptors.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Nele Van den Eede, Adrian Covaci.
- Journal Title
  
  Toxicol. Lett.
  
  Volume: 245 Pages: 31-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172
[Journal Article] Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors alpha and gamma.2015
- Author(s)
  Hiroyuki Kojima, Yukimasa Takeda, Ryuta Muromoto, Miki Takahashi, Toru Hirao, Shinji Takeuchi, Anton M Jetten, and Tadashi Matsuda
- Journal Title
  
  Toxicology
  
  Volume: 329 Pages: 32-39
- DOI
  10.1016/j.tox.2015.01.007
- NAID
  120005712473
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25460056, KAKENHI-PROJECT-24390172
[Journal Article] Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.2015
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Seigo Sanoh, Kazumi Sugihara, Shigeyuki Kitamura, and Shigeru Ohta
- Journal Title
  
  Toxicology and Applied Pharmacology
  
  Volume: 282 Issue: 2 Pages: 119-128
- DOI
  10.1016/j.taap.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] 化学物質のリスク評価における肝肥大の取扱いの基本的考え方2015
- Author(s)
  吉田緑、梅村隆志、小島弘幸、井上薫、高橋美和、北村繁幸、浦丸直人、安部賀央里、頭金正博、小澤正吾、吉成浩一
- Journal Title
  
  食品衛生学雑誌
  
  Volume: 56 Pages: 42-48
- NAID
  130005067294
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590773
[Journal Article] Basic Principles of Interpretation of Hepatocellular Hypertrophy in Risk Assessment in Japan2015
- Author(s)
  Yoshida M., Umemura T., Kojima H., Inoue K., Takahashi M., Uramaru N., Kitamura S., Abe K., Tohkin M., Ozawa S., Yoshinari K.,
- Journal Title
  
  Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
  
  Volume: 56 Issue: 2 Pages: 42-48
- DOI
  10.3358/shokueishi.56.42
- NAID
  130005067294
- ISSN
  0015-6426, 1882-1006
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25340049, KAKENHI-PROJECT-24390172
[Journal Article] Review; A sensitive, rapid and simple DR-EcoScreen bioassay for the determination of PCDD/Fs and dioxin-like PCBs in environmental and food samples.2015
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Shoji F. Nakayama, and Takuya Shiozaki
- Journal Title
  
  Environmental Science and Pollution Research
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590773
[Journal Article] Reduction of Bromine Compounds in Oil Produced from Brominated Flame Retardant Plastics via Pyrolysis Using a Reflux Condenser.2014
- Author(s)
  Hlaing ZZ, Wajima T, Uchiyama S, Nakagome H.
- Journal Title
  
  International Journal of Environmental Science and Development
  
  Volume: 5 Pages: 207-211
- DOI
  10.7763/ijesd.2014.v5.479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172
[Journal Article] Detection of 34 plasticizers and 25 flame retardants in indoor air from houses in Sapporo, Japan.2014
- Author(s)
  Takeuchi S, Kojima H, Saito I, Jin K, Kobayashi S, Tanaka-Kagawa T, Jinno H.
- Journal Title
  
  Sci Total Environ
  
  Volume: in progress Pages: 1-8
- DOI
  10.1016/j.scitotenv.2014.04.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] Simple and rapid determination of PCDD/Fs in flue gases from various waste incinerators in China using DR-EcoScreen cells.2014
- Author(s)
  Zhou Z, Zhao B, Kojima H, Takeuchi S, Takagi Y, Tateishi N, Iida M, Shiozaki T, Xu P, Qi L, Ren Y, Li N, Zheng S, Zhao H, Fan S, Zhang T, Liu A, Huang Y.
- Journal Title
  
  Chemosphere
  
  Volume: 102 Pages: 24-30
- DOI
  10.1016/j.chemosphere.2013.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] Comparative study on transcriptional activity of 17 parabens mediated by estrogen receptor α and β and androgen receptor2013
- Author(s)
  Watanabe Y., Kojima H., Takeuchi S., Uramaru N., Ohta S, Kitamura S
- Journal Title
  
  Food and Chemical Toxicology
  
  Volume: 57 Pages: 227-234
- DOI
  10.1016/j.fct.2013.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510071, KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773, KAKENHI-PROJECT-24790126, KAKENHI-PROJECT-25340049
[Journal Article] Determination of Carbonyl Compounds Generated from the E-cigarette Using Coupled Silica Cartridges Impregnated with Hydroquinone and 2,4-Dinitrophenylhydrazine, Followed by High-Performance Liquid Chromatography2013
- Author(s)
  Uchiyama S, Ohta K, Inaba Y, Kunugita N.
- Journal Title
  
  Anal. Sci.
  
  Volume: 29 Issue: 12 Pages: 1219-1222
- DOI
  10.2116/analsci.29.1219
- NAID
  130004827331
- ISSN
  0910-6340, 1348-2246
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-25560361
[Journal Article] In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors.2013
- Author(s)
  Kojima H, Takeuchi S, Itoh T, Iida M, Kobayashi S, Yoshida T.
- Journal Title
  
  Toxicology
  
  Volume: 314 Issue: 1 Pages: 76-83
- DOI
  10.1016/j.tox.2013.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172, KAKENHI-PROJECT-24590773
[Journal Article] Smoking topography and biomarkers of exposure among Japanese smokers : associations with cigarette emissions obtained using machine smoking protocols2013
- Author(s)
  Matsumoto M, Inaba Y, Yamaguchi I, Endo O, Hammond D, Uchiyama S, Suzuki G.
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 18 Pages: 95-103
- NAID
  10031162104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172
[Journal Article] Smoking topography and biomarkers of exposure among Japanese smokers: associations with cigarette emissions from machine smoking protocols2013
- Author(s)
  Matsumoto M, Inaba Y, Yamaguchi I, Endo O, Hammond D, Uchiyama S, Suzuki G
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: 18 Issue: 2 Pages: 95-103
- DOI
  10.1007/s12199-012-0293-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500645, KAKENHI-PROJECT-22510079, KAKENHI-PROJECT-24390172
[Journal Article] イソフラボン類のIL-17産生増強作用2013
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田　正
- Journal Title
  
  ImmunoTox Letter (日本免疫毒性学会誌)
  
  Volume: 18（2） Pages: 12-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590773
[Journal Article] Simultaneous determination of volatile organic compounds and carbonyls in mainstream cigarette smoke using a sorbent cartridge followed by two-step elution.2013
- Author(s)
  Uchiyama S, Tomizawa T, Inaba Y, Kunugita N.
- Journal Title
  
  J Chromatogr A
  
  Volume: 1314 Pages: 31-37
- DOI
  10.1016/j.chroma.2013.09.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172
[Journal Article] A diffusive sampling device for measurement of ammonia in air2012
- Author(s)
  Yamada T, Uchiyama S, Inaba Y, Kunugita N, Nakagome N, Seto H.
- Journal Title
  
  Atmospheric Environment
  
  Volume: 54 Pages: 629-633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390172
[Journal Article] Reductive amination of glutaraldehyde 2,4-dinitrophenylhydrazone using 2-picoline borane and high-performance liquid chromatographic analysis.2012
- Author(s)
  Uchiyama. S..; Sakamoto, H.; Ohno, A.; Inaba, Y.; Nakagome, H.; Kunugita, N.
- Journal Title
  
  Analyst
  
  Volume: 137 Issue: 18 Pages: 4274-4279
- DOI
  10.1039/c2an35230c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510079, KAKENHI-PROJECT-22790126, KAKENHI-PROJECT-24390172
[Journal Article] Ozone removal in the collection of carbonyl compounds in air.2012
- Author(s)
  Uchiyama. S..; Inaba, Y.; Kunugita, N.
- Journal Title
  
  Journal of Chromatography A
  
  Volume: 1229 Pages: 293-297
- DOI
  10.1016/j.chroma.2012.01.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510079, KAKENHI-PROJECT-24390172
[Journal Article] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptorsαandγ2012
- Author(s)
  Kojima H, Muromoto R, Takahashi M, Takeuchi S, Takeda Y, Jetten AM, and Matsuda T.
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 259 Issue: 3 Pages: 338-345
- DOI
  10.1016/j.taap.2012.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675, KAKENHI-PROJECT-23390015, KAKENHI-PROJECT-23790067
[Journal Article] Determination of dioxin concentrations in fish and seafood samples using a highly sensitive reporter cell line, DR-EcoScreen cells2011
- Author(s)
  Kojima H, Takeuchi S, Tsutsumi T, Yamaguchi K, Anezaki K, Kubo K, Iida M, Takahashi T, Kobayashi S, Jin K and Nagai T.
- Journal Title
  
  Chemosphere
  
  Volume: 83 Issue: 6 Pages: 753-759
- DOI
  10.1016/j.chemosphere.2011.02.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative Study of Human and Mouse Pregnane X Receptor Agonistic Activity in 200 Pesticides Using Reporter Gene Assays2011
- Author(s)
  Hiroyuki Kojima, Fumihiro Sata, Shinji Takeuchi, Tatsuya Sueyoshi, Tadanori Nagai
- Journal Title
  
  Toxicology
  
  Volume: VOL.280 Pages: 77-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Determination of Dioxin Concentrations in Fish and Seafood Samples Using a Highly Sensitive Reporter Cell Line, DR-EcoScreen Cells2011
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Tomoaki Tsutsumi, Katsuyuki Yamaguchi, Katsunori Anezaki, Keiko Kubo, Mitsuru Iida, Tetsuo Takahashi, Satoshi Kobayashi, Kazuo Jin, Tadanori Nagai
- Journal Title
  
  Chemosphere
  
  Volume: VOL.83 Pages: 753-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2011
- Author(s)
  Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K and Kojima H.
- Journal Title
  
  Toxicology
  
  Volume: 280 Issue: 2-3 Pages: 112-121
- DOI
  10.1016/j.tox.2011.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675, KAKENHI-PROJECT-22510071
[Journal Article] Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using reporter gene assays2011
- Author(s)
  Kojima H, Sata F, Takeuchi S, Sueyoshi T and Nagai T.
- Journal Title
  
  Toxicology
  
  Volume: 280 Issue: 3 Pages: 77-87
- DOI
  10.1016/j.tox.2010.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] 水性塗料成分1-メチル-2-ピロリドン及びテキサノールによる新築小学校の室内空気汚染2010
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫、秋津裕志、伊佐治信一
- Journal Title
  
  日本室内環境学会誌 (掲載確定, 印刷中)
- NAID
  40017162386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] [Minireview]Endocrine-disrupting Potential of Pesticides via Nuclear Receptors and Aryl Hydrocarbon Receptor2010
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Tadanori Nagai
- Journal Title
  
  Journal of Health Science (掲載確定, 印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] 農薬による核内受容体RORα/γを介したIL-17遺伝子発現に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Journal Title
  
  ImmunoTox Letter(日本免疫毒性学会)
  
  Volume: 15(2) Pages: 4-6
- URL
  http://www.immunotox.org/immunotoxletter/pdf/30vol15no2-2010J.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] 生体異物センサー;PXRとCARを介した内分泌撹乱作用2010
- Author(s)
  小島弘幸
- Journal Title
  
  Endocrine Disrupter NEWS LETTER(環境ホルモン学会)
  
  Volume: 13(1) Pages: 4-4
- URL
  http://www.jsedr.jp/newsletter/news1.htm#13-1
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Endocrine-disrupting potential of pesticides via nuclear receptors and aryl hydrocarbon receptor2010
- Author(s)
  Kojima H, Takeuchi S. and Nagai T.
- Journal Title
  
  J. Health Sci.
  
  Volume: 56(4) Pages: 374-386
- NAID
  130000303536
- URL
  https://www.jstage.jst.go.jp/article/jhs/56/4/56_4_374/_pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Journal Title
  
  Environmental Health Perspectives
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Application of a Bioassay Using DR-EcoScreen Cells to the Determination of Dioxins in Ambient Air : A Comparative Study with HRGC-HRMS Analysis2009
- Author(s)
  Katsunori Anezaki, Katsuyuki Yamaguchi, Shinji Takeuchi, Mitsuru Iida, Kazuo Jin, Hiroyuki Kojima
- Journal Title
  
  Environmental Science & Technology VOL.43
  
  Pages: 7478-7483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Journal Title
  
  Environmental Health Perspectives VOL.117
  
  Pages: 1210-1218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative Study on the Nuclear Hormone Receptor Activity of Various Phytochemicals and Their Metabolites by Reporter Gene Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Shinji Takeuchi, Tetsuo Takahashi, Yukiharu Sawada, Mitsuru Iida, Tadashi Matsuda, Hiroyuki Kojima
- Journal Title
  
  Biological & Pharmaceutical Bulletin 32(2)
  
  Pages: 195-202
- NAID
  110007042163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T. and Kitamura S.
- Journal Title
  
  Environ. Health Perspect
  
  Volume: 117 Issue: 8 Pages: 1210-1218
- DOI
  10.1289/ehp.0900753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylated and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells.2009
- Author(s)
  Kojima H., Takeuchi S., Uramaru N., Sugihara K., Yoshida T., and Kitamura S.
- Journal Title
  
  Environmental Health Perspectives (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Application of a bioassay using DR-EcoScreen cells to the determination of dioxins in ambient air : A comparative study with HRGC-HRMS analysis2009
- Author(s)
  Anezaki K, Yamaguchi K, Takeuchi S, Iida M, Jin K. and Kojima H.
- Journal Title
  
  Environ. Sci. Technol
  
  Volume: 43 Issue: 19 Pages: 7478-7483
- DOI
  10.1021/es901003b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590675
[Journal Article] Comparative study on the nuclear hormone receptor activity of various phytochemicals and their metabolites by reporter gene assays using Chinese hamster ovary cells.2009
- Author(s)
  Takeuchi S., Takahashi T., Sawada Y., Iida M., Matsuda T., and Kojima H.
- Journal Title
  
  Biological & Pharmaceutical Bulletin 32
  
  Pages: 195-202
- NAID
  110007042163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] In Vitro Screening for Aryl Hydrocarbon Receptor Agonistic Activity in 200 Pesticides Using a Highly Sensitive Reporter Cell Line, DR-EcoScreen Cells, and in Vivo Mouse Liver Cytochrome P450-1A Induction by Propanil, Diuron and Linuron2008
- Author(s)
  Shinji Takeuchi, Mitsuru Iida, Hisatoshi Yabushita, Tadashi Matsuda, Hiroyuki Kojima
- Journal Title
  
  Chemosphere 74
  
  Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron.2008
- Author(s)
  Takeuchi S., Iida M., Yabushita H., Matsuda T., and Kojima H.
- Journal Title
  
  Chemosphere 74
  
  Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] 改修工事に伴いシックハウス症候群が発生したマンションにおける室内空気中化学物質の測定と症状誘発に関与した物質の推定2007
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫、渡辺一彦
- Journal Title
  
  北海道立衛生研究所報 57
  
  Pages: 23-28
- NAID
  120006794425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] 化学物質過敏症患者の症状に関与する室内空気中化学物質の検索(第3報)2007
- Author(s)
  武内伸治、小島弘幸、小林智、高橋哲夫
- Journal Title
  
  北海道立衛生研究所報 57
  
  Pages: 29-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Journal Article] Determination of dioxins in emission gas, ash and atomospheric air samples using a highly sensitive AhR-mediated reporter cell line, DR-EcoScreen cells.2007
- Author(s)
  Kojima H., Takeuchi S., Anezaki K., Yamaguchi K., Otsuka H., Sawadaishi K., Honda K., Yabushita H., and Iida M.
- Journal Title
  
  Organohalogen Compounds 69
  
  Pages: 1234-1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] ユビキチンリガーゼTRAF6によるAhRの新規活性制御の解析2024
- Author(s)
  箱田涼, 村瀬渉, 安田彩夏, 窪田篤人, 進藤つぐみ, 土田史郎, 小島弘幸, 中川宏治
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] 前思春期のフタル酸エステル類曝露とステロイドホルモン値との関連：北海道スタディ2024
- Author(s)
  安田彩夏、アイツバマイゆふ、山口健史、Rahel Mesfin Ketema、曾怡、池中良徳、宮下ちひろ、Megasari Marsela、岸玲子、小島弘幸、池田敦子
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] 前思春期のフタル酸エステル類曝露とステロイドホルモン値との関連：北海道スタディ2024
- Author(s)
  安田彩夏、アイツバマイゆふ、山口健史、Rahel Mesfin Ketema、池中良徳、宮下ちひろ、Megasali Marsera、岸玲子、小島弘幸、池田敦子
- Organizer
  第94回日本衛生学会
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] ペルフルオロオクタン酸（PFOA）の代替物質 GenX による新生仔マウス肝臓での遺伝子発現に及ぼす影響2024
- Author(s)
  村瀬渉, 窪田篤人, 箱田涼, 安田彩夏, 池田敦子, 小島弘幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] PFOA 曝露による肝細胞での遺伝子発現プロファイルと次世代への影響2023
- Author(s)
  村瀬渉, 窪田篤人, 池田敦子, 小島弘幸
- Organizer
  第２回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] ペルフルオロオクタン酸(PFOA)による核内受容体活性化を介した遺伝子発現プロファイル.2023
- Author(s)
  村瀬渉、窪田篤人、木村ゆり、池田敦子、小島弘幸
- Organizer
  日本薬学会第143回年会. 北海道大学、札幌
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] PFOA曝露による肝細胞での遺伝子発現プロファイルと次世代への影響2023
- Author(s)
  村瀬渉、窪田篤人、池田敦子、小島弘幸
- Organizer
  第２回環境化学物質３学会合同大会
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] 高残留性ペルフルオロオクタン酸（PFOA）のヒト及びマウス肝細胞に及ぼす影響2023
- Author(s)
  村瀬渉, 窪田篤人, 池田敦子, 小島弘幸
- Organizer
  日本薬学会北海道支部第150回例会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] フタル酸ジ(2-エチルヘキシル)代謝物の核内受容体活性プロファイルと HepaRG 細胞への曝露影響2023
- Author(s)
  安田彩夏、村瀬渉、窪田篤人、浦丸直人、奥田勝博、箱田涼、池田敦子、小島弘幸
- Organizer
  フォーラム2023衛生薬学・環境とエコロジー
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] 成分栄養療法の制御性T細胞誘導に及ぼす抗菌薬併用の影響2023
- Author(s)
  窪田篤人, 村瀬渉, 今井俊吾, 菅原満, 武隈洋, 小島弘幸
- Organizer
  第30回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K11454
[Presentation] レポーター遺伝子アッセイ法を用いた下水処理水及び河川水中の内分泌かく乱活性の測定2022
- Author(s)
  窪田篤人、中田典秀、高田秀重、五味麻尋、寺崎将、小島弘幸
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] フコキサンチンによる膵がん予防に対する免疫関連分子制御の検討2022
- Author(s)
  村瀬渉、寺崎将、窪田篤人、安田彩夏、植原治、田中卓二、高橋真美、小島弘幸
- Organizer
  第29回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] レポーター遺伝子アッセイ法を用いた下水処理水及び河川水中の内分泌かく乱活性の測定2022
- Author(s)
  窪田篤人、中田典秀、高田秀重、五味麻尋、寺崎将、小島弘幸
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] レポーター遺伝子アッセイ法を用いた下水処理水及び河川水中の内分泌かく乱活性の測定2022
- Author(s)
  窪田篤人, 中田典秀, 高田秀重, 五味茉尋, 寺崎将, 小島弘幸
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] プラスチック製品中のフェノール系内分泌攪乱物質の溶出2022
- Author(s)
  坂根史紀、水川薫子、窪田篤人、小島弘幸、高田秀重
- Organizer
  環境化学物質3学会合同大会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] Gene expression profiles in human HepaRG liver cells treated with perfluorooctanoic acid (PFOA)2022
- Author(s)
  Atsuhito Kubota, Masaru Terasaki, Yuri Kimura, Atsuko Ikeda-Araki, Reiko Kishi, Hiroyuki Kojima
- Organizer
  International Society for Environmental Epidemiology Asia and Western Pacific Chapter & International Society for Exposure Science Asia Chapter Joint Conference 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] ucoxanthinolによるCLIC4依存性がん細胞アポトーシス誘導機構2022
- Author(s)
  横山怜央, 窪田篤人, 小島弘幸, 寺崎将
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] レポーター遺伝子アッセイ法を用いた下水処理水及び河川水中の内分泌かく乱活性の測定2022
- Author(s)
  窪田篤人、中田典秀、高田秀重、五味麻尋、寺崎将、小島弘幸
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] 同所移植マウス膵がんモデルにおけるFucoxanthinによるがん化学予防2022
- Author(s)
  村瀬渉, 窪田篤人, 小島弘幸, 寺崎将
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] 5-ASA による脾臓 Treg 誘導と機序の解明2021
- Author(s)
  窪田篤人、寺崎将、高井理恵、小林正紀、室本竜太、小島弘幸
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] プラスチック添加剤による核内受容体を介した内分泌系・免疫系のかく乱作用2021
- Author(s)
  小島弘幸
- Organizer
  第23回環境ホルモン学会研究発表会・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] 同種同所マウス膵がんモデルにおけるFucoxanthinによるがん予防2021
- Author(s)
  村瀬渉、窪田篤人、小島弘幸、寺崎将
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] 5-ASA による脾臓 Treg 誘導と機序の解明2021
- Author(s)
  窪田篤人、寺崎将、高井理恵、小林正紀、室本竜太、小島弘幸
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] プラスチック添加剤・ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した免疫毒性作用2021
- Author(s)
  小島弘幸、窪田篤人、寺崎将、室本竜太、高田秀重
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] 5-ASA による脾臓 Treg 誘導と機序の解明2021
- Author(s)
  窪田篤人、寺崎将、高井理恵、小林正紀、室本竜太、小島弘幸
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した制御性T細胞の誘導2021
- Author(s)
  窪田篤人、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] プラスチック添加剤・ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した免疫毒性作用2021
- Author(s)
  小島弘幸、窪田篤人、寺崎将、室本竜太、高田秀重
- Organizer
  第48回日本毒性学会学術年会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] プラスチック添加剤による核内受容体を介した内分泌系・免疫系のかく乱作用2021
- Author(s)
  小島弘幸
- Organizer
  第23回環境ホルモン学会研究発表会・シンポジウム
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] ベンゾトリアゾール系UV吸収剤のAhRアゴニスト活性と免疫系に及ぼす影響2021
- Author(s)
  窪田篤人、桜木優太、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] プラスチック添加剤・ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した免疫毒性作用2021
- Author(s)
  小島弘幸、窪田篤人、寺崎将、室本竜太、高田秀重
- Organizer
  第48回日本毒性学会学術年会・シンポジウム
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] プラスチック添加剤・ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した免疫毒性作用2021
- Author(s)
  小島弘幸、窪田篤人、寺崎将、室本竜太、高田秀重
- Organizer
  第48回日本毒性学会学術年会・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] FucoxanthinolによるCLIC4依存性がん細胞アポトーシス誘導機構2021
- Author(s)
  横山怜央、窪田篤人、小島弘幸、寺崎将
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] ベンゾトリアゾール系UV吸収剤のAhRアゴニスト活性と免疫系に及ぼす影響2021
- Author(s)
  窪田篤人、桜木優太、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] プラスチック添加剤による核内受容体を介した内分泌系・免疫系のかく乱作用2021
- Author(s)
  小島弘幸
- Organizer
  第23回環境ホルモン学会研究発表会・シンポジウム
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した制御性T細胞の誘導2021
- Author(s)
  窪田篤人、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した制御性T細胞の誘導2021
- Author(s)
  窪田篤人、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  日本免疫毒性学会第28学術年会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] ベンゾトリアゾール系UV吸収剤によるAhR活性化を介した制御性T細胞の誘導2021
- Author(s)
  窪田篤人、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-21H04843
[Presentation] Cell-based assay法を用いたUV吸収剤のホルモン受容体を介したエストロゲン・抗アンドロゲン作用の検出2020
- Author(s)
  桜木優太、寺崎将、小島弘幸
- Organizer
  日本薬学会北海道支部第147回例会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] マイクロプラスチック由来化学物質におけるヒトエストロゲン受容体alpha/betaアゴニスト活性の比較2020
- Author(s)
  桜木優太、寺崎将、武内伸治、小島弘幸
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Cell-based assay法を用いたUV吸収剤のホルモン受容体を介したエストロゲン・抗アンドロゲン作用の検出2020
- Author(s)
  1.桜木優太、寺崎将、小島弘幸
- Organizer
  日本薬学会北海道支部第147回例会
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Cell-based assay法を用いたUV吸収剤のホルモン受容体を介したエストロゲン・抗アンドロゲン作用の検出2020
- Author(s)
  桜木優太、寺崎将、小島弘幸
- Organizer
  日本薬学会北海道支部第147回例会
- Data Source
  KAKENHI-PROJECT-20H00627
[Presentation] ベンゾトリアゾール系UV吸収剤のAhRアゴニスト活性と免疫系に及ぼす影響2020
- Author(s)
  2.窪田篤人、桜木優太、寺崎将、室本竜太、高田秀重、小島弘幸
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Cell-besed assay法を用いたUV吸収剤のホルモン受容体を介したエストロゲン・抗アンドロゲン作用の検出2020
- Author(s)
  桜木優太、寺崎将、小島弘幸
- Organizer
  第147回日本薬学会北海道支部例会
- Data Source
  KAKENHI-PROJECT-20K05879
[Presentation] マイクロプラスチック由来化学物質におけるヒトエストロゲン受容体alpha/beta;アゴニスト活性の比較2020
- Author(s)
  桜木優太、寺崎将、武内伸治、小島弘幸
- Organizer
  日本薬学会第140年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] 環境化学物質による核内受容体活性の探索と免疫毒性作用2019
- Author(s)
  小島弘幸
- Organizer
  第162回日本獣医学会学術集会（日本比較薬理学・毒性学会シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] 環境化学物質による核内受容体活性の探索と免疫毒性作用2019
- Author(s)
  小島弘幸
- Organizer
  第162回日本獣医学会学術集会（日本比較薬理学・毒性学会シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Effects of perfluorocarboxylic acids on transcriptional activity via human nuclear receptors and gene expression in human macrophage-like THP-1 cells.2019
- Author(s)
  Kojima H, Takeuchi S, Okuda K, Muromoto R, Kishi R, Araki A.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Effects of perfluorocarboxylic acids on transcriptional activity via human nuclear receptors and gene expression in human macrophage-like THP-1 cells.2019
- Author(s)
  Kojima H, Takeuchi S, Okuda K, Muromoto R, Kishi R, Araki A.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Measurement of dioxin-related compounds in trace biological samples using highly sensitive cells, DR-EcoScreenHS bioassay.2019
- Author(s)
  Matsuda R, Nakamura M, Kojima H, Iida M.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Distribution of 58 semi-volatile organic chemicals in the gas phase and three particle sizes in indoor air and house dust in residential buildings during the hot season in Japan.2019
- Author(s)
  Takeuchi S, Tanaka-Kagawa T, Saito I, Kojima H, Jinno H.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10611
[Presentation] Measurement of dioxin-related compounds in trace biological samples using highly sensitive cells, DR-EcoScreenHS bioassay.2019
- Author(s)
  Matsuda R, Nakamura M, Kojima H, Iida M.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Distribution of 58 semi-volatile organic chemicals in the gas phase and three particle sizes in indoor air and house dust in residential buildings during the hot season in Japan.2019
- Author(s)
  Takeuchi S, Tanaka-Kagawa T, Saito I, Kojima H, Jinno H.
- Organizer
  39th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] Effects of essential oil constituents on in vitro transcriptional activities via estrogen and androgen receptors, and in silico molecular docking study.2018
- Author(s)
  Takeuchi S, Okuda K, Sugihara K, Kojima H.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Effects of essential oil constituents on in vitro transcriptional activity via estrogen and androgen receptors, and in an in silico molecular docking study2018
- Author(s)
  Takeuchi S, Okuda K, Sugihara K, Kojima H.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] ヒトマクロファージ様THP-1細胞の遺伝子発現に及ぼす核内受容体アゴニストの曝露影響2018
- Author(s)
  小島弘幸、武内伸治、室本竜太、岸玲子、荒木敦子
- Organizer
  第25回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] In vitro and in silico studies on PPARalpha/gamma and PXR activation by di-(2-ethylhexyl) phthalate and its metabolites.2018
- Author(s)
  Kojima H, Okuda K, Uramaru N, Kitamura S, Takeuchi S, Muromoto R, Sugihara K, Kishi R, Araki A.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] フタル酸エステルとその代謝物が核内受容体PXRおよびPPARαの転写活性に及ぼす影響2018
- Author(s)
  佐藤志穂、渡部容子、立花研、浦丸直人、小島弘幸、吉成浩一、樋口敏幸、北村繁幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] フタル酸エステルとその代謝物が核内受容体PXRおよびPPARalphaの転写活性に及ぼす影響2018
- Author(s)
  佐藤志穂、渡部容子、立花研、浦丸直人、小島弘幸、吉成浩一、樋口敏幸、北村繁幸
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] In vitro and in silico studies on PPAR and PXR activation by di-(2-ethylhexyl) phthalate and its metabolites.2018
- Author(s)
  Kojima H, Okuda K, Uramaru N, Kitamura S, Takeuchi S, Muromoto R, Sugihara K, Kishi R, Araki A
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] In vitro and in silico studies on PPARα/γand PXR activation by di-(2-ethylhexyl) phthalate and its metabolites2018
- Author(s)
  Kojima H, Okuda K, Uramaru N, Kitamura S, Takeuchi S, Muromoto R, Sugihara K, Kishi R, Araki A.
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] 核内受容体活性を指標とした化学物質の毒性影響評価2018
- Author(s)
  小島弘幸
- Organizer
  生物化学的測定研究会第23回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03035
[Presentation] ヒトマクロファージ様THP-1細胞の遺伝子発現に及ぼすDEHPとMEHPの曝露影響2017
- Author(s)
  小島弘幸、武内伸治、室本竜太、岸玲子、荒木敦子
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] ベンゾトリアゾール系紫外線吸収剤のPXR, CARおよびPPARアルファ活性とシトクロムP450活性への影響2017
- Author(s)
  服部祥子、渡部容子、立花研、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] ヒトマクロファージ様THP-1細胞の遺伝子発現に及ぼすDEHPとMEHPの曝露影響2017
- Author(s)
  小島弘幸、武内伸治、室本竜太、岸玲子、荒木敦子
- Organizer
  第24回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] カルバメート系農薬のラットおよびヒトでのin vitro代謝とその核内受容体活性への影響2017
- Author(s)
  藤野智恵里、渡部容子、浦丸直人、佐能生剛、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] LC/TOF-MS及び薬物受容体アッセイを用いた危険ドラッグ成分のスクリーニング2017
- Author(s)
  武内伸治、佐藤正幸、小島弘幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Effects of photopolymerization initiators on in vitro transcriptional activities via nuclear receptors.2017
- Author(s)
  Takeuchi S, Kojima H.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] カルバメート系農薬のラットおよびヒトでのin vitro代謝とその核内受容体活性への影響2017
- Author(s)
  藤野智恵里、渡部容子、浦丸直人、佐能生剛、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市（仙台国際センター）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] リン系難燃剤のラット核内受容体PXR, CARおよびPPARalpha;に対するアゴニスト活性2017
- Author(s)
  柳川ひらり、渡部容子、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市（仙台国際センター）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] C/TOF-MS及び薬物受容体アッセイを用いた危険ドラッグ成分のスクリーニング2017
- Author(s)
  武内伸治、佐藤正幸、小島弘幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市（仙台国際センター）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] ベンゾトリアゾール系紫外線吸収剤のPXR, CARおよびPPARalpha活性とシトクロムP450活性への影響2017
- Author(s)
  服部祥子、渡部容子、立花研、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市（仙台国際センター）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Biochanin Aによる核内受容体ROR;活性化機構の解析2017
- Author(s)
  室本竜太、高橋美妃、小島弘幸、武内伸治、松田正
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Characterization of the endocrine disruption potential of bisphenol A structural analogues via human nuclear receptors.2017
- Author(s)
  Kojima H, Takeuchi S, Sanoh S, Kitamura S, Uramaru N, Sugihara K, Yoshinari K.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Characterization of the endocrine disruption potential of bisphenol A structural analogues via human nuclear receptors.2017
- Author(s)
  Kojima H, Takeuchi S, Sanoh S, Kitamura S, Uramaru N, Sugihara K, Yoshinari K.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Biochanin Aによる核内受容体RORgamma活性化機構の解析2017
- Author(s)
  室本竜太、高橋美妃、小島弘幸、武内伸治、松田正
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Effects of photopolymerization initiators on in vitro transcriptional activities via nuclear receptors.2017
- Author(s)
  Takeuchi S, Kojima H.
- Organizer
  The 14th International Symposium on Persistent Toxic Substances (ISPTS 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] リン系難燃剤のラット核内受容体PXR, CARおよびPPARアルファに対するアゴニスト活性2017
- Author(s)
  柳川ひらり、渡部容子、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター(宮城県・仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] パラベン、サリチル酸エステル及びフタル酸エステルの核内受容体活性の構造活性相関2016
- Author(s)
  津越幸枝、谷川悠華、渡部容子、浦丸直人、小島弘幸、北村繁幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] パラベン、サリチル酸エステル及びフタル酸エステルの核内受容体活性の構造活性相関2016
- Author(s)
  津越幸枝、谷川悠華、渡部容子、浦丸直人、小島弘幸、北村繁幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 環境化学物質による核内受容体を介した免疫毒性作用2016
- Author(s)
  小島弘幸
- Organizer
  第23回日本免疫毒性学会
- Place of Presentation
  北九州コンベンションセンター（福岡県・北九州市）
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Comparative study on the in vitro nuclear receptor activities of di-(2-ethylhexyl) phthalate and its five metabolites2016
- Author(s)
  Hiroyuki Kojima, Naoto Uramaru, Shigeyuki Kitamura, Shinji Takeuchi S, Reiko Kishi, Atsuko Araki
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Hokkaido University, Sapporo, Japan
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 危険ドラッグの迅速検知に向けたバイオアッセイ系について2016
- Author(s)
  小島弘幸、武内伸治
- Organizer
  第68回北海道公衆衛生学会
- Place of Presentation
  札幌市立大学桑園キャンパス(北海道・札幌市）
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 環境化学物質による核内受容体を介した免疫毒性作用2016
- Author(s)
  小島弘幸
- Organizer
  第23回日本免疫毒性学会
- Place of Presentation
  北九州市（北九州コンベンションセンター）
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Comparison of the forms of plasticizers and organophosphorus flame retardants present in residential indoor air in different seasons2016
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Masayuki Sato, Satoshi Kobayashi, Hiroyuki Kojima, Ikue Saito, Hitoshi Uemura, Hideto Jinno
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Hokkaido University, Sapporo, Japan
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 生活用品等に含まれる精油成分の性ホルモン受容体を介した作用2016
- Author(s)
  武内伸治、佐藤正幸、小林智、小島弘幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Effects of unintentional PCBs in pigments and chemical products on transcriptional activity via 10 nuclear receptors and aryl hydrocarbon receptor2016
- Author(s)
  Shinji Takeuchi, Katsunori Anezaki, Hiroyuki Kojima
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe International Conference Center, Kobe, Japan
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Characterization of thyroid hormone receptor and retinoid X receptor activities in 100 hydroxylated polychlorinated biphenyls using CHO-K1 cell-based transactivation assays2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fujio Shiraishi, Hiroaki Kuroki, Shigeyuki Kitamura
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe International Conference Center, Kobe, Japan
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 環境化学物質と核内受容体－Cell-based Assay法を用いた毒性評価と環境測定－2016
- Author(s)
  小島弘幸
- Organizer
  第30回薬物作用談話会
- Place of Presentation
  札幌市（北海道大学獣医学部）
- Invited
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Comparative study on the in vitro nuclear receptor activities of di-(2-ethylhexyl) phthalate and its five metabolites.2016
- Author(s)
  Hiroyuki Kojima, Naoto Uramaru, Shigeyuki Kitamura, Shinji Takeuchi S, Reiko Kishi, Atsuko Araki
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Sapporo (Japan)
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] ffects of unintentional PCBs in pigments and chemical products on transcriptional activity via 10 nuclear receptors and aryl hydrocarbon receptor.2016
- Author(s)
  Shinji Takeuchi, Katsunori Anezaki, Hiroyuki Kojima
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe (Japan)
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Environmental pollutant PFCAs are phenobarbital-like indirect human and mouse CAR activators.2016
- Author(s)
  Mirei Takahashi, Taiki Abe, Hiroyuki Kojima, Takamitsu Sasaki, Takuomi Hosaka, Kouichi Yoshinari
- Organizer
  11th International Society for the Study of Xenobiotics (ISSX) Meeting
- Place of Presentation
  Busan (South Korea)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 生活用品等に含まれる精油成分の性ホルモン受容体を介した作用2016
- Author(s)
  武内伸治、佐藤正幸、小林智、小島弘幸
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Comparison of the forms of plasticizers and organophosphorus flame retardants present in residential indoor air in different seasons.2016
- Author(s)
  Shinji Takeuchi, Toshiko Tanaka-Kagawa, Masayuki Sato, Satoshi Kobayashi, Hiroyuki Kojima, Ikue Saito, Hitoshi Uemura, Hideto Jinno
- Organizer
  Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter (ISEE-ISES AC 2016)
- Place of Presentation
  Sapporo (Japan)
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 環境化学物質と核内受容体－Cell-based Assay法を用いた毒性評価と環境測定－2016
- Author(s)
  小島弘幸
- Organizer
  第30回薬物作用談話会
- Place of Presentation
  北海道大学獣医学部（北海道・札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 危険ドラッグの迅速検知に向けたバイオアッセイ系について2016
- Author(s)
  小島弘幸、武内伸治
- Organizer
  第68回北海道公衆衛生学会
- Place of Presentation
  札幌市（札幌市立大学桑園キャンパス）
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 環境汚染物質perfluorocarboxylic acids (PFCAs) によるマウス及びヒトCAR活性化作用2016
- Author(s)
  高橋美玲,阿部大樹,小島弘幸,保坂卓臣,佐々木崇光,吉成浩一
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウインクあいち（愛知県・名古屋市）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 環境汚染物質perfluorocarboxylic acids (PFCAs) によるマウス及びヒトCAR活性化作用2016
- Author(s)
  高橋美玲、阿部大樹、小島弘幸、保坂卓臣、佐々木崇光、吉成浩一
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  名古屋市（ウインクあいち）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Characterization of thyroid hormone receptor and retinoid X receptor activities in 100 hydroxylated polychlorinated biphenyls using CHO-K1 cell-based transactivation assays.2016
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fujio Shiraishi, Hiroaki Kuroki, Shigeyuki Kitamura
- Organizer
  The 9th International PCB Workshop
- Place of Presentation
  Kobe (Jaoan)
- Year and Date
  2016-10-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] パーソナルケア製品に含まれる化学物質によるERalpha/beta及びPXRを介した内分泌撹乱活性2015
- Author(s)
  渡部容子、小島弘幸、武内伸治、藤本成明、北村繁幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌市（札幌コンベンションセンター）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] パーソナルケア製品に含まれる化学物質によるERα/β及びPXRを介した内分泌撹乱活性2015
- Author(s)
  渡部容子、小島弘幸、武内伸治、藤本成明、北村繁幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌コンベンションセンター (北海道・札幌市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] サリチル酸及びサリチル酸エステル類の核内受容体ER, AR, PXR及びCARに対する作用2015
- Author(s)
  谷川悠華、小山賢一、渡部容子、浦丸直人、小島弘幸、藤本成明、北村繁幸
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス (兵庫県・神戸市)
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds.2015
- Author(s)
  Hiroyuki Kojima, Seigo Sanoh, Shinji Takeuchi, Kazumi Sugihara, Koichi Yoshinari, Shigeyuki Kitamura.
- Organizer
  54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego (USA)
- Year and Date
  2015-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] 核内受容体の転写活性化を介した新規甲状腺ホルモンかく乱機構の解析2015
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス (兵庫県・神戸市)
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 化学物質と核内受容体：毒性評価・環境測定・創薬への展開2015
- Author(s)
  小島弘幸
- Organizer
  北海道大学環境健康科学研究教育センター公開セミナー
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2015-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Endocrine-disrupting potential of environmental chemicals. via nuclear receptors.2015
- Author(s)
  Hiroyuki Kojima.
- Organizer
  Seminar in National Health Research Institutes
- Place of Presentation
  Zhunan (Taiwan)
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] Endocrine-disrupting potential of environmental chemicals via nuclear receptors2015
- Author(s)
  Hiroyuki Kojima
- Organizer
  Seminar in National Health Research Institutes
- Place of Presentation
  National Health Research Institutes (Taiwan)
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] サリチル酸及びサリチル酸エステル類の核内受容体ER, AR, PXR及びCARに対する作用2015
- Author(s)
  谷川悠華、小山賢一、渡部容子、浦丸直人、小島弘幸、藤本成明、北村繁幸
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 化学物質による複雑な肝毒性を予測および評価するためのインビトロ・インシリコ統合型システムの開発2015
- Author(s)
  吉成浩一、小島弘幸
- Organizer
  2015年LRI研究報告会
- Place of Presentation
  ベルサール神田 (東京都・千代田区)
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] リン系難燃剤のラット肝カルボキシルエステラーゼ活性に対する阻害効果2015
- Author(s)
  渡部容子、井上智賀、谷川悠華、浦丸直人、杉原数美、小島弘幸、北村繁幸
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Endocrine-disrupting potential of environmental chemicals via nuclear receptors.2015
- Author(s)
  Hiroyuki Kojima
- Organizer
  Seminar in National Health Research Institutes (Taiwan)
- Place of Presentation
  Zhunan, Taiwan
- Year and Date
  2015-11-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ.2015
- Author(s)
  Hiroyuki Kojima, Yukimasa Takeda, Ryuta Muromoto, Miki Takahashi, Toru Hirao, Shinji Takeuchi, Anton M. Jetten, Tadashi Matsuda.
- Organizer
  54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego (USA)
- Year and Date
  2015-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] STAT3活性化を介したIL-17A遺伝子発現に及ぼすバイオカニンAの影響2015
- Author(s)
  小島弘幸、室本竜太、高橋美妃、平尾徹、松田正
- Organizer
  第22 回日本免疫毒性学会
- Place of Presentation
  京都大学 (京都府・京都市)
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の測定2015
- Author(s)
  武内伸治、香川（田中）聡子、斎藤育江、小島弘幸、佐藤正幸、小林智、神野秀人
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] STAT3活性化を介したIL-17A遺伝子発現に及ぼすバイオカニンAの影響2015
- Author(s)
  小島弘幸、室本竜太、高橋美妃、平尾徹、松田正
- Organizer
  第22 回日本免疫毒性学会
- Place of Presentation
  京都市（京都大学百周年時計台記念館国際交流ホール）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 色素や化成品に含まれるPCBの核内受容体及びダイオキシン受容体を介した作用2015
- Author(s)
  武内伸治、姉崎克典、小島弘幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌市（札幌コンベンションセンター）
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] リン系難燃剤のラット肝カルボキシルエステラーゼ活性に対する阻害効果2015
- Author(s)
  渡部容子、井上智賀、谷川悠華、浦丸直人、杉原数美、小島弘幸、北村繁幸
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス (兵庫県・神戸市)
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 核内受容体の転写活性化を介した新規甲状腺ホルモンかく乱機構の解析2015
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸市（神戸学院大学ポートアイランドキャンパス）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 色素や化成品に含まれるPCBの核内受容体及びダイオキシン受容体を介した作用2015
- Author(s)
  武内伸治、姉崎克典、小島弘幸
- Organizer
  第24回環境化学討論会
- Place of Presentation
  札幌コンベンションセンター (北海道・札幌市)
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 化学物質による複雑な肝毒性を予測および評価するためのインビトロ・インシリコ統合型システムの開発2015
- Author(s)
  吉成浩一、小島弘幸
- Organizer
  2015年LRI研究報告会
- Place of Presentation
  東京都（ベルサール神田）
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15K08791
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の測定2015
- Author(s)
  武内伸治、香川（田中）聡子、斎藤育江、小島弘幸、佐藤正幸、小林智、神野秀人
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス (兵庫県・神戸市)
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H04780
[Presentation] 居住住宅における室内空気中の可塑剤及び有機リン系難燃剤の分別定量2014
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林　智、小島弘幸、斎藤育江、上村　仁、田中(香川)聡子、神野透人
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス他(熊本市)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 肝肥大誘導性ペルフルオロオクタン酸とその類縁化合物によるヒト及びラット核内受容体活性の比較．2014
- Author(s)
  小島　弘幸　他．
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] 化学物質の核内受容体活性化と肝肥大作用－in vitro試験を用いた解析－．2014
- Author(s)
  小島弘幸、北村繁幸、浦丸直人、吉成浩一．
- Organizer
  第41回日本毒性学会学術年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2014-07-02
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] 肝肥大誘導性ペルフルオロオクタン酸とその類縁化合物によるヒト及びラット核内受容体活性の比較2014
- Author(s)
  小島弘幸、武内伸治、中島宏之、野表知世、藤野智恵理、浦丸直人、北村繁幸、吉成浩一
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス他(熊本市)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Comparative study on human and mouse nuclear receptor activities of hepatomegaly-inducing perfluorooctanoic acid and its related compounds.2014
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fumihiro Sata, Hiroyuki Nakajima, Chise Noomote, Chieri Fujino, Naoto Uramaru, Shigeyuki Kitamura, Koichi Yoshinari.
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Bangkok　（Thailand)
- Year and Date
  2014-11-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] Effects of perfluoroalkylcarboxylic acids and phthalate metabolite on transcriptional activity via PPARA and PPARA-V227A variant.2013
- Author(s)
  Kojima H et al.
- Organizer
  8th World Congress on Developmental Origins of Health and Disease (DOHaD 2013)
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] ラット肝ミクロソームによるベンゾフェノン系紫外線吸収剤の代謝とエストロゲン活性の変動2013
- Author(s)
  白鳥由衣, 渡部容子, 小島弘幸, 武内伸治, 江森千紘, 浦丸直人, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Effects of environmental chemicals on interleukin-17 production via aryl hydrocarbon receptor2013
- Author(s)
  Hiroyuki Kojima, Ryuta Muromoto, Miki Takahashi, Shinji Takeuchi, Tadashi Matsuda
- Organizer
  33th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2013)
- Place of Presentation
  Hotel Inter-Burgo, Daegu (Republic of Korea)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 紫外線吸収剤ベンゾフェノン-3 のラットおよびヒトによる代謝とエストロゲンおよび抗アンドロゲン活性の変動2013
- Author(s)
  渡部容子, 小島弘幸, 武内伸治, 長本哲明, 浦丸直人, 太田茂, 北村繁幸
- Organizer
  日本薬学会第133 年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Detection of 34 plasticizers and 25 flame retardants in indoor air from houses in Sapporo, Japan2013
- Author(s)
  Shinji Takeuchi, Hiroyuki Kojima, Ikue Saito, Kazuo Jin, Satoshi Kobayashi, Toshiko Tanaka-Kagawa, Hideto Jinno
- Organizer
  33th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2013)
- Place of Presentation
  Hotel Inter-Burgo, Daegu (Republic of Korea)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] イソフラボン類によるSTAT3とRORgammaを介したIL-17産生増強作用2013
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田　正
- Organizer
  第20回日本免疫毒性学会
- Place of Presentation
  東海大学代々木キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体RORalpha/gamma依存的IL-17産生に及ぼすイソフラボン類の影響2013
- Author(s)
  小島弘幸
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体を介した転写活性化試験による毒性評価・環境測定・創薬への展開．2013
- Author(s)
  小島　弘幸．
- Organizer
  日本薬科大学・平成25年度特別講演会
- Place of Presentation
  日本薬科大学
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] Effects of environmental chemicals on interleukin-17 production via aryl hydrocarbon receptor.2013
- Author(s)
  Kojima H et al.
- Organizer
  33th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin 2013)
- Place of Presentation
  Teague
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] Effects of perfluoroalkylcarboxylic acids and phthalate metabolite on transcriptional activity via PPARA and PPARA-V227A variant2013
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Kenichi Takahashi, Fumihiro Sata
- Organizer
  The 8th World Conference on Developmental Origins of Health and Diseases (DOHaD 2013)
- Place of Presentation
  SUNTEC Singapore (Singapore)
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体RORα/γ依存的IL-17産生に及ぼすイソフラボン類の影響2013
- Author(s)
  小島弘幸、高橋美妃、武田行正、室本竜太、武内伸治、Jetten AM、松田正
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] 核内受容体を介した転写活性化試験による毒性評価・環境測定・創薬への展開2013
- Author(s)
  小島　弘幸
- Organizer
  日本薬科大学・平成25年度特別講演会
- Place of Presentation
  日本薬科大学(埼玉県伊奈町)
- Invited
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] イソフラボン類によるSTAT3とRORを介したIL-17産生増強作用．2013
- Author(s)
  小島　弘幸　他．
- Organizer
  第20回日本免疫毒性学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] マウスEL4細胞のIL-17及びIL-22遺伝子発現に及ぼすAhRアゴニストの影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  第19回日本免疫毒性学会
- Place of Presentation
  東京慈恵会医科大学(東京都)
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptorsαandγ2012
- Author(s)
  Kojima H, Muromoto R, Takahashi M, Takeuchi S, Takeda Y, Jetten AM, and Matsuda T.
- Organizer
  The 51st Annual Meeting of the Society of Toxicology(SOT)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 環境化学物質における核内受容体RORα/γ活性の探索とIL-17遺伝子発現への影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 環境化学物質における核内受容体RORα/γ活性の探索とIL-17遺伝子発現への影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 炎症性サイトカインIL-17産生に及ぼすBiochanin Aの影響に関する研究2012
- Author(s)
  高橋美妃、室本竜太、小島弘幸、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 抗菌剤パラベン類の内分泌撹乱作用の特徴と構造活性相関2012
- Author(s)
  渡部容子, 小島弘幸, 武内伸治, 浦丸直人, 太田茂, 北村繁幸
- Organizer
  フォーラム 2012 衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Metabolism of parabens by rat liver microsomes and its modification of the endocrine-disrupting activity.2012
- Author(s)
  Uramaru, N., Watanabe, Y.,. Kitamura, S.,Takeuchi S., Kojima H
- Organizer
  SETAC (The Society of Environmental Toxicology and Chemistry) Asia Pacific 2012 Meeting Abstract
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ2012
- Author(s)
  Hiroyuki Kojima, Ryuta Muromoto, Miki Takahashi, Shinji Takeuchi, Yukimasa Takeda, Anton M.Jetten, Tadashi Matsuda
- Organizer
  The 51st Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Francisco
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ダイオキシン受容体を介したIL-17遺伝子発現に及ぼす環境化学物質の影響2012
- Author(s)
  小島弘幸
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京都（東京大学山上会館）
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2012
- Author(s)
  Takeuchi S, Shiraishi F, Kitamura S, Kuroki H, Jin K and Kojima H.
- Organizer
  The 51st Annual Meeting of the Society of Toxicology(SOT)
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 炎症性サイトカインIL-17産生に及ぼすBiochanin Aの影響に関する研究2012
- Author(s)
  高橋美妃、室本竜太、小島弘幸、武内伸治、松田正
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] マウスEL4細胞のIL-17及びIL-22遺伝子発現に及ぼすAhRアゴニストの影響2012
- Author(s)
  小島弘幸
- Organizer
  第19回日本免疫毒性学会
- Place of Presentation
  東京都（東京慈恵会医科大学）
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 室内空気中から検出された光重合開始剤及びその類似化合物の核内受容体を介した作用2012
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ダイオキシン受容体を介したIL-17遺伝子発現に及ぼす環境化学物質の影響2012
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-24390172
[Presentation] 室内空気中から検出された光重合開始剤及びその類似化合物の核内受容体を介した作用2012
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  日本薬学会第132年会総会
- Place of Presentation
  札幌市(北海道大学)
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Metabolism of benzophenone-3, a sunscreen, by rat liver microsomes and modification of the endocrine-disrupting activity2012
- Author(s)
  Kitamura S., Watanabe Y., Uramaru N., Takeuchi S., Kojima H.
- Organizer
  SETAC (The Society of Environmental Toxicology and Chemistry) Asia Pacific 2012 Meeting Abstract
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Characterization of steroid hormone receptor activities in 100 hydroxylated polychlorinated biphenyls, including congeners identified in humans2012
- Author(s)
  Shinji Takeuchi, Fujio Shiraishi, Shigeyuki Kitamura, Hiroaki Kuroki, Kazuo Jin, Hiroyuki Kojima
- Organizer
  The 51st Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Francisco
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORγt依存的なIL-17遺伝子発現誘導に対するイソフラボン類の影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  第18回日本免疫毒性学会
- Place of Presentation
  千葉大学けやき会館(千葉市)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORγt依存的なIL-17遺伝子発現誘導に対するイソフラボン類の影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  第18回日本免疫毒性学会
- Place of Presentation
  千葉市(千葉大学けやき会館)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORα/γ依存的なIL-17産生に及ぼすBiochanin Aの影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] トリクロサン及びその塩素化誘導体の13種類の核内受容体への作用2011
- Author(s)
  武内伸治、兼俊明夫、小林智、北村繁幸、小島弘幸
- Organizer
  日本薬学会第131年会総会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 遺伝子導入細胞を用いた環境・食品試料中のダイオキシン類簡易測定法の開発2011
- Author(s)
  小島弘幸
- Organizer
  道央バイオ研究交流会「平成22年度研究発表会」
- Place of Presentation
  恵庭リサーチビジネスパーク・センタービル(恵庭市)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 遺伝子導入細胞を用いた環境・食品試料中のダイオキシン類簡易測定法の開発2011
- Author(s)
  小島弘幸
- Organizer
  道央バイオ研究交流会・平成22年度研究発表会
- Place of Presentation
  恵庭市(恵庭リサーチビジネスパーク・センタービル)
- Year and Date
  2011-02-25
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中化学物質における核内受容体活性のプロファイル2011
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  金沢市(金沢エクセルホテル東急)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 室内空気中化学物質における核内受容体活性のプロファイル2011
- Author(s)
  武内伸治、小林智、小島弘幸
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  金沢エクセルホテル東急(金沢市)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] RORα/γ依存的なIL-17産生に及ぼすBiochanin Aの影響2011
- Author(s)
  小島弘幸、室本竜太、高橋美妃、武内伸治、松田正
- Organizer
  環境ホルモン学会第14回研究発表会
- Place of Presentation
  東京都(東京大学山上会館)
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] トリクロサン及びその塩素化誘導体の13種類の核内受容体への作用2011
- Author(s)
  武内伸治、兼俊明夫、小林智、北村繁幸、小島弘幸
- Organizer
  日本薬学会第131年会総会
- Place of Presentation
  静岡市(ツインメッセ静岡)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ビスフェノールA関連物質の核内受容体PXR/CARを介した転写活性に及ぼす影響2010
- Author(s)
  小島浩幸, 他
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロギー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites Based on Transactivation Assays2010
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Organizer
  5th International Symposium on Brominated Flame Retardants
- Place of Presentation
  Kyoto University Clock Tower, Kyoto, Japan
- Year and Date
  2010-04-08
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬200物質におけるレチノイド関連オーファン受容体(ROR)活性の探索とIL-17産生に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  第17回日本免疫毒性学会学術大会
- Place of Presentation
  つくば市(国立環境研究所・大山記念ホール)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ビスフェノールA関連物質の核内受容体PXR/CARを介した転写活性に及ぼす影響2010
- Author(s)
  小島弘幸、佐能正剛、武内伸治、杉原数美、北村繁幸
- Organizer
  フォーラム2010衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  東京都(星薬科大学)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬による核内受容体RORα/γインバースアゴニスト活性と免疫系への影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ビスフェノールA関連物質の核内受容体PXR/CARを介した転写活性に及ぼす影響2010
- Author(s)
  小島弘幸、佐能正剛、武内伸治、杉原数美、北村繁幸
- Organizer
  フォーラム2010 衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  星薬科大学(東京都)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬による核内受容体RORα/γインバースアゴニスト活性と免疫系への影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  環境ホルモン学会第13回研究発表会
- Place of Presentation
  東京都(東京大学山上会館)
- Year and Date
  2010-12-16
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylarted and methoxylated metabolites based on transactivation assays2010
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T and Kitamura S.
- Organizer
  5th International Symposium on Brominated Flame Retardants
- Place of Presentation
  Kyoto University, Japan
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear hormone receptor activity of polychlorinated biphenyls and their hydroxylated and methoxylated metabolites based transactivation assays2010
- Author(s)
  Kojima, et al.
- Organizer
  5^<th> International Symposium on Brominated Flame Retardants
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-22510071
[Presentation] 臭素化難燃剤PBDE水酸化体の核内受容体アゴニスト及びアンタゴニスト活性2010
- Author(s)
  小島弘幸、武内伸治、杉原数美、浦丸直人、北村繁幸
- Organizer
  日本薬学会第130年会総会
- Place of Presentation
  桃太郎アリーナ(岡山市)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDE水酸化体の核内受容体アゴニスト及びアンタゴニスト活性2010
- Author(s)
  小島弘幸、武内伸治、杉原数美、浦丸直人、北村繁幸
- Organizer
  日本薬学会第130年会総会
- Place of Presentation
  岡山市(桃太郎アリーナ)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 農薬200物質におけるレチノイド関連オーファン受容体(ROR)活性の探索とIL-17産生に及ぼす影響2010
- Author(s)
  小島弘幸、武内伸治、高橋美妃、室本竜太
- Organizer
  第17回日本免疫毒性学会学術大会
- Place of Presentation
  国立環境研究所・大山記念ホール(つくば市)
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 高感度レポーターアッセイ法を用いた環境化学物質の核内受容体活性の検出およびダイオキシン類生物検定法への適用2009
- Author(s)
  小島弘幸
- Organizer
  生物化学的測定研究会第14回学術シンポジウム
- Place of Presentation
  つくばインフォメーションセンター(つくば市)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 高感度レポーターアッセイ法を用いた環境化学物質の核内受容体活性の検出およびダイオキシン類生物検定法への適用2009
- Author(s)
  小島弘幸
- Organizer
  生物化学的測定研究会第14回学術シンポジウム
- Place of Presentation
  つくば市(つくばインフォメーションセンター)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸, 武内伸治, 佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-20659104
[Presentation] 臭素化難燃剤PBDE及びそれら代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132例会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear Hormone Receptor Activity of Brominated Diphenyl Ethers and Their Hydroxylarted and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells2009
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Takahiko Yoshida, Shigeyuki Kitamura
- Organizer
  HORIBA International Conference/CDBIM Symposium : 21th Century Advances in the Molecular Toxicology of Environmental Chemicals and Pathogenesis of Disease
- Place of Presentation
  東京大学鉄門記念講堂(東京都)
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸、武内伸治、佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  宜野湾市(沖縄コンベンションセンター)
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDE及びそれら代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132例会
- Place of Presentation
  札幌市(札幌コンベンションセンター)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] Nuclear hormone receptor activity of brominated diphenyl ethers and their hydroxylarted and methoxylated metabolites in transactivation assays using Chinese hamster ovary cells2009
- Author(s)
  Kojima H, Takeuchi S, Uramaru N, Sugihara K, Yoshida T and Kitamura S.
- Organizer
  HORIBA International Conference/CDBIM Symposium : 21th Century Advances in the Molecular Toxicology of Environmental Chemicals and Pathogenesis of Disease
- Place of Presentation
  Tokyo University, Japan
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] ピレスロイド系殺虫剤によるヒト及びマウスPXR/CARを介した転写活性の比較2009
- Author(s)
  小島弘幸、武内伸治、佐田文宏
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2009-11-05
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 臭素化難燃剤PBDEおよびその代謝物によるホルモン受容体を介した内分泌撹乱作用2009
- Author(s)
  小島弘幸、武内伸治、浦丸直人、杉原数美、北村繁幸
- Organizer
  日本薬学会北海道支部第132回例会
- Place of Presentation
  札幌市(札幌コンベンションホール)
- Year and Date
  2009-05-30
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] TR, PDIへの親和性に対する臭素化難燃剤の構造活性相関2009
- Author(s)
  岩瀬恵理、佐能正剛、今岡進、岡田和嗣、加藤善久、小島弘幸、浦丸直人、杉原数美、北村繁幸、黒木広明、太田茂
- Organizer
  フォーラム2009衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  沖縄コンベンションセンター(宜野湾市)
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21590675
[Presentation] 植物由来化学物質における核内受容体PXR及びPPARα/β/γアゴニスト作用2009
- Author(s)
  武内伸治、飯田満、高橋哲夫、小島弘幸
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市(国立京都国際会館)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素化難燃剤PBDEの甲状腺ホルモン受容体結合活性の代謝による変動2009
- Author(s)
  岩瀬恵理、小島弘幸、杉原数美、浦丸直人、藤本成明、黒木広明、北村繁幸、太田茂
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都市(国立京都国際会館)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素系難燃剤ポリブロモジフェニルエーテル及びその代謝物における核内受容体活性のプロファイル2008
- Author(s)
  小島弘幸、武内伸治、浦丸直人、北村繁幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] シックハウス症候群の発症に関連する化学物質の検索システムの開発と実際例2008
- Author(s)
  小林智、武内伸治、小島弘幸、高橋哲夫、神和夫
- Organizer
  日本分析化学会北海道支部2008冬季研究発表会
- Place of Presentation
  札幌市(北大学術交流会館)
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 農薬200物質におけるヒト及びマウスPXRアゴニスト活性のスクリーニング2008
- Author(s)
  小島弘幸、武内伸治、佐田文宏、根岸正彦
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京都(東京ビッグサイト)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素系及び有機リン系難燃剤による核内受容体PXRの活性化2008
- Author(s)
  小島弘幸、武内伸治、小林智、伊藤俊弘、吉田貴彦
- Organizer
  第17回日本臨床環境医学会学術集会
- Place of Presentation
  旭川市(旭川ターミナルホテル)
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] PCB水酸化体100物質におけるグルココルチコイド受容体活性のスクリーニング2008
- Author(s)
  武内伸治、小島弘幸、神和夫、北村繁幸、黒木広明、白石不二雄
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京都(東京ビッグサイト)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 農薬200物質におけるヒト及びマウスPXRアゴニスト活性のスクリーニング2008
- Author(s)
  小島弘幸, 武内伸治, 佐田文宏, 根岸正彦
- Organizer
  第11回日本内分泌撹乱化学物質学会
- Place of Presentation
  東京ビッグサイト(東京)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-20659104
[Presentation] 植物由来機能成分の核内受容体を介した作用2008
- Author(s)
  武内伸治、小島弘幸、松田正、澤田幸治
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜市(パシフィコ横浜)
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 有機リン系難燃剤における核内受容体活性のプロファイル2008
- Author(s)
  小島弘幸、武内伸治、小林智、伊藤俊弘、吉田貴彦
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  熊本市(熊本市民会館)
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた大気中ダイオキシン類の測定(第2報)2008
- Author(s)
  姉崎克典、山口勝透、芥川智子、武内伸治、小島弘幸
- Organizer
  第17回環境化学討論会
- Place of Presentation
  神戸市(神戸国際会議場)
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 脂溶性食品添加物における核内受容体活性のプロファイル2008
- Author(s)
  武内伸治、小島弘幸、松田正
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  熊本市(熊本市民会館)
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 臭素化難燃剤PBDEおよびTBBPAの代謝と内分泌撹乱作用の検討2008
- Author(s)
  岩瀬恵理、小島弘幸、杉原数美、浦丸直人、黒木広明、北村繁幸、太田茂
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  熊本市(熊本市民会館)
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた大気中ダイオキシン類の測定とAhR活性物質の同定2007
- Author(s)
  姉崎克典、山口勝透、芥川智子、小島弘幸、武内伸治、藪下尚智、飯田満
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] PCB水酸化体100物質におけるアンロゲン受容体活性のスクリーニング2007
- Author(s)
  武内伸治、小島弘幸、北村繁幸、黒木広明、白石不二雄
- Organizer
  第10回日本内分泌撹乱化学物質学会
- Place of Presentation
  さいたま市(大宮ソニックシティ)
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] Determination of dioxins in emission gas, ash and atomospheric air samples using a highly sensitive AhR-mediated reporter cell line, DR-EcoScreen cells.2007
- Author(s)
  Kojima H., Takeuchi S., Anezaki K., Yamaguchi K., Otsuka H., Sawadaishi K., Honda K., Yabushita H., and Iida M.
- Organizer
  27th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] シックスクールで検出された未規制化学物質(1-メチル-2-ピロリドン及びテキサノール)濃度の推移と発生源の探索2007
- Author(s)
  小林智、高橋哲夫、武内伸治、小島弘幸、神和夫
- Organizer
  平成19年度室内環境学会総会
- Place of Presentation
  仙台市(東北文化学園大学)
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた魚介類中ダイオキシン類簡易測定法の開発2007
- Author(s)
  小島弘幸、武内伸治、堤智昭、山口勝透、高橋哲夫、小林智、藪下尚智、飯田満
- Organizer
  第10回日本内分泌撹乱化学物質学会
- Place of Presentation
  さいたま市(大宮ソニックシティ)
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 高感度AhRレポーター細胞を用いた排出ガス及びばいじん中ダイオキシン類の測定2007
- Author(s)
  小島弘幸、武内伸治、山口勝透、大塚英幸、姉崎克典、澤田石一之、本田克久、藪下尚智、飯田満
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] PCB水酸化体100物質におけるエストロゲン受容体α/β活性のスクリーニング2007
- Author(s)
  武内伸治、小島弘幸、北村繁幸、黒木広明、白石不二雄
- Organizer
  フォーラム2007衛生薬学・環境トキシコロジー(日本薬学会主催)
- Place of Presentation
  大阪市(アピオ大阪森ノ宮ピロティホール)
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] 迅速で簡便な酵母を用いるAhRアゴニスト活性のアッセイ法について2007
- Author(s)
  武内伸治、白石不二雄、鎌田亮、中島大介、小島弘幸、滝上英孝、鈴木規之、白石寛明
- Organizer
  第16回環境化学討論会
- Place of Presentation
  北九州市(北九州国際会議場)
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590610
[Presentation] In vitro endocrine-disrupting effects of pesticides via nuclear receptors.
- Author(s)
  Hiroyuki Kojima
- Organizer
  第17回北海道大学・ソウル大学ジョイントシンポジウム
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2014-11-27 – 2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Characterization of human and mouse PXR- and CAR-mediated transcriptional activation by bisphenol A and its related compounds.
- Author(s)
  Hiroyuki Kojima, Seigo Sanoh, Shinji Takeuchi, Kazumi Sugihara, Koichi Yoshinari, Shigeyuki Kitamura
- Organizer
  The 54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Year and Date
  2015-03-23 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の分別定量（第２報）
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林智、小島弘幸、斎藤育江、上村仁、香川(田中)聡子、神野透人
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Effects of metabolism of UV-absorbers by rat liver microsomes on their nuclear receptor activation.
- Author(s)
  Yoko Watanabe, Hiroyuki Kojima, Shinji Takeuchi, Naoto Uramaru, Kazumi Sugihara, Seigo Sanoh, Shigeru Ohta, Shigeyuki Kitamura
- Organizer
  34th International Symposium on Halogenated Persistent Organic Pollutants (Dioxin2014)
- Place of Presentation
  Melia Castilla hotel (Madrid, Spain)
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 抗菌剤パラベン類のヒトおよびラットPXR, CAR, PPARalpha活性
- Author(s)
  藤野智恵里、渡部容子、浦丸直人、小島弘幸、吉成浩一、北村繁幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Isoflavones enhance interleukin-17 gene expression via retinoic acid receptor-related orphan receptors alpha and gamma.
- Author(s)
  Hiroyuki Kojima, Yukimasa Takeda, Ryuta Muromoto, Miki Takahashi, Toru Hirao, Shinji Takeuchi, Anton M Jetten, and Tadashi Matsuda
- Organizer
  The 54th Annual Meeting of the Society of Toxicology (SOT)
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Year and Date
  2015-03-23 – 2015-03-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Differential determination of plasticizers and organophosphorus flame retardants in residential indoor air.
- Author(s)
  Shinji Takeuchi, Kazuo Jin, Masayuki Sato, Satoshi Kobayashi, Hiroyuki Kojima, Ikue Saito, Hidenori Uemura, Toshiko Tanaka-Kagawa, Hideto Jinno
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 香粧品香料のヒトおよびラットPXR, CAR, PPARalpha, AhRに対するアゴニスト活性
- Author(s)
  渡部容子、小島弘幸、浦丸直人、杉原数美、吉成浩一、太田茂、北村繁幸
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Comparative study on human and mouse nuclear receptor activities of hepatomegaly-inducing perfluorooctanoic acid and its related compounds.
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Fumihiro Sata, Hiroyuki Nakajima, Chise Noomote, Chieri Fujino, Naoto Uramaru, Shigeyuki Kitamura, Koichi Yoshinari
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体PXRおよびCAR転写活性に対する甲状腺ホルモン構造類似物質の影響
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] Application of a bioassay using DR-EcoScreen cells to the determination of dioxins in environmental and food samples: comparative studies using HRGC-HRMS analysis.
- Author(s)
  Hiroyuki Kojima, Shinji Takeuchi, Mitsuru Iida, Takuya Shiozaki
- Organizer
  International Conference of Asian Environmental Chemistry (ICAEC2014)
- Place of Presentation
  Convention Center, Chulabhorn Research Institute (Bangkok, Thailand)
- Year and Date
  2014-11-24 – 2014-11-26
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] レポーターアッセイ系を用いた香粧品香料によるPXR, CAR, PPARalphaおよびAhR活性の評価
- Author(s)
  渡部容子、小島弘幸、浦丸直人、藤本成明、杉原数美、吉成浩一、太田茂、北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] ピレスロイド系およびカルバメート系農薬のラットPXR, CARおよびPPARalpha活性と肝代謝による影響
- Author(s)
  藤野智恵里、渡部容子、浦丸直人、小島弘幸、吉成浩一、北村繁幸
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 化学物質の核内受容体活性化作用と肝肥大作用；In vitro 試験を用いた解析
- Author(s)
  小島弘幸、北村繁幸、浦丸直人、吉成浩一
- Organizer
  第41回日本毒性学会学術年会シンポジウム
- Place of Presentation
  神戸コンベンションセンター(神戸市)
- Year and Date
  2014-07-02 – 2014-07-04
- Invited
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 核内受容体PXRおよびCAR転写活性作用を示す甲状腺ホルモン構造類似環境化学物質のスクリーニング
- Author(s)
  清水良、渡部容子、浦丸直人、小島弘幸、武内伸治、黒木広明、太田茂、北村繁幸、杉原数美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590773
[Presentation] 居住住宅における室内環境中の可塑剤及び有機リン系難燃剤の分別定量
- Author(s)
  武内伸治、神和夫、佐藤正幸、小林智、小島弘幸、斎藤育江、上村仁、香川(田中)聡子、神野透人
- Organizer
  フォーラム2014衛生薬学・環境トキシコロジー
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2014-09-19 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-24590773

1. TAKEUCHI Shinji (20414287)

# of Collaborated Projects: 7 results

# of Collaborated Products: 139 results
2. YOSHIDA Takahiko (90200998)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. MUROMOTO Ryuta (30455597)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
4. Atsuko Araki (00619885)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. ITOH Toshihiro (20271760)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. URAMARU Naoto (90424069)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
7. KISHI Reiko (80112449)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
8. 宮下ちひろ (70632389)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
9. アイツバマイゆふ (90752907)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. SAKABE Koh (70162302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KOBAYASHI Satoshi (00414285)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
12. Sata Fumihiro (90187154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
13. NAKAGI Yoshihiko (90322908)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KOBAYASHI Sumitaka (10733371)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
15. TERASAKI Masaru (10391195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
16. 池中良徳 (40543509)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. OKUDA Katsuhiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
18. CHIBA Masahiro (90414292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KITAMURA Shigeyuki (40136057)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
20. FUJIMOTO Nariaki (40243612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SUGIHARA Kazumi (20271067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. KASHIWAGI Akihiko (50106796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. UCHIYAMA Shigehisa (40524236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
24. HIRAKU Yusuke (30324510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KONISHI Kanae (70238103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SAIJO Yasuaki (70360906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MATSUDA Tadashi (20212219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
28. SUGIOKA Yoshihiko (30398747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. SHIMIZU Hiroshi (00146672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. MINATOYA Machiko (50733367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 鈴木智宏 (10414327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 乃村俊史 (50399911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 守屋仁彦 (20374233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 武藤倫弘 (30392335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
35. 高橋真美 (90214973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
36. 高田秀重 (70187970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
37. 中田典秀 (00391615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. 内田圭一 (50313391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 水川薫子 (50636868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
40. Goudarzi Houman (40713607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 山口健史 (80894972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
42. 惠淑萍 (90337030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 中村明枝 (90724708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 増田秀幸 (20869119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. POUDEL KRITIKA (40893764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 窪田篤人 (70879931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
47. SUGANO Youhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. ITO Sachiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
49. TAKEDA Mai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. KAWAI Toshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. ENDO Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. NAKAGOME Hideki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. MAEDA Hayato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 姉崎克典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 松沢厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kojima hiroyuki 小島 弘幸

KOJIMA Hiroyuki 小島 弘幸

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Measurement of AhR activity in human serum using a cell-besed assay and its application for epidemiological studyPrincipal Investigator

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Effects of microplastic-derived chemicals on functions of regulatory T cells via nuclear receptor Nr4a.Principal Investigator

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Effects of chemical mixtures contained in foods on immune response via nuclear receptors.Principal Investigator

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Effects of environmental chemicals on Th17 cells differenciation via aryl hydrocarbon receptorPrincipal Investigator

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Effects of environmental chemicals on differentiation of helper-T 17 cells via retinoic acid receptor-related orphan receptorsPrincipal Investigator

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Effects of Indoor Air Chemicals on Transcriptional Activities via Nuclear Receptors and Dioxin ReceptorPrincipal Investigator

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kojima hiroyuki 小島弘幸

KOJIMA Hiroyuki 小島弘幸