Kotani Hitoshi 小谷仁司

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KOTANI Hitoshi 小谷仁司

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Researcher Number	10594640
Other IDs
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 講師
Affiliation (based on the past Project Information) *help	2018 – 2023: 島根大学, 学術研究院医学・看護学系, 講師 2013 – 2017: 武蔵野大学, 薬学研究所, 助教 2013: 武蔵野大学, 薬学部, 助教 2012: 慶應義塾大学, 医学部, 特任助教 2011: 愛知学院大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Natural medicines / Basic Section 47050:Environmental and natural pharmaceutical resources-related / General internal medicine (including Psychosomatic medicine) Except Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Chemical pharmacy
Keywords	Principal Investigator 天然物 / 癌 / 生薬 / スクリーニング / T細胞 / 自己免疫疾患 / 制御性T細胞 / RXR / 核内受容体 / 伝統医薬品 … More / 老化 / 免疫疲弊 / タンパク質間相互作用 / 低分子化合物 / PD-L1 / PD-1 / 免疫チェックポイント / 生活習慣病 / ヘテロダイマー / 分化制御 / リガンド / NR4A2 / Treg / サイトカイン / ジンコウ / インターフェロンガンマ / 沈香 / 免疫賦活 / 厚朴 / LXR / honokiol / 漢方方剤 / レチノイド / 動脈硬化 / メタボリックシンドローム / 天然物化学 / 生薬学 / 東洋医学 … More Except Principal Investigator 連続型環化反応 / ケミカルプローブ / キナーゼ阻害 / 全合成 / 連続環化 / クロロスペルミン / アクリドン / ベンザイン / pimaradienoic acid / 天然物 / ドッカツ / 漢方繁用生薬 / 制御性T細胞 / 生薬 / RARアゴニスト / レチノイン酸受容体 / 漢方薬繁用生薬 / 肥満 / 食物アレルギー / キサントフィル / ジテルペン / 天然物化学 / 核内受容体 / レチノイン酸受容体アゴニスト Less

ベンザインの位置選択的連続型環化反応を機軸とする生物活性アクリドンの合成研究
- Principal Investigator
  
  片川和明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  湘南医療大学
   Musashino University
Search for traditional drugs and naturally derived compounds that act on immune checkpoints and analyze their effectivenessPrincipal Investigator
- Principal Investigator
  
  Kotani Hitoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Shimane University
Natural-derived agonist search and activation mechanism analysis for nuclear receptor without ligand pocketPrincipal Investigator
- Principal Investigator
  
  Kotani Hitoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Natural medicines
- Research Institution
  Shimane University
  Musashino University
The search and functional analysis of the natural compound promoting the differentiation of regulatory T cells.Principal Investigator
- Principal Investigator
  
  KOTANI Hitoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Natural medicines
- Research Institution
  Musashino University
Search for naturally occurring retinoic acid receptor agonists and thier application to immune and allergic diseases
- Principal Investigator
  
  INOUE Makoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Aichi Gakuin University
Clarify the meaning of Magnolia obovata in Kampo medicine on nuclear receptor activation.Principal Investigator
- Principal Investigator
  
  KOTANI Hitoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Keio University
  Aichi Gakuin University

All 2023 2022 2021 2020 2019 2018 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] T-cell responses and combined immunotherapy against human carbonic anhydrase 9-expressing mouse renal cell carcinoma2021
- Author(s)
  Harada Mamoru、Iida Yuichi、Kotani Hitoshi、Minami Takafumi、Komohara Yoshihiro、Eto Masatoshi、Yoshikawa Kazuhiro、Uemura Hirotsugu
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 71 Issue: 2 Pages: 339-352
- DOI
  10.1007/s00262-021-02992-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-19H03794, KAKENHI-PROJECT-21K07177
[Journal Article] Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor‐induced senescence in breast cancer cells2021
- Author(s)
  Kartika Irna D.、Kotani Hitoshi、Iida Yuichi、Koyanagi Akira、Tanino Ryosuke、Harada Mamoru
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 24 Pages: 8988-8999
- DOI
  10.1002/cam4.4410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-21K07177
[Journal Article] Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells2020
- Author(s)
  Iida Yuichi、Yoshikawa Rintaro、Murata Akihiko、Kotani Hitoshi、Kazuki Yasuhiro、Oshimura Mitsuo、Matsuzaki Yumi、Harada Mamoru
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 8 Issue: 2 Pages: e000582-e000582
- DOI
  10.1136/jitc-2020-000582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-18K08297, KAKENHI-PROJECT-19K16713
[Journal Article] Immunogenic chemotherapy in two mouse colon cancer models2020
- Author(s)
  Taniura Takahito、Iida Yuichi、Kotani Hitoshi、Ishitobi Kazunari、Tajima Yoshitsugu、Harada Mamoru
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 10 Pages: 3527-3539
- DOI
  10.1111/cas.14624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393
[Journal Article] Supplementation of l ‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy2020
- Author(s)
  Satoh Yusuke、Kotani Hitoshi、Iida Yuichi、Taniura Takahito、Notsu Yoshitomo、Harada Mamoru
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2248-2258
- DOI
  10.1111/cas.14490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393
[Journal Article] Pemetrexed Sensitizes Human Lung Cancer Cells to Cytotoxic Immune Cells2020
- Author(s)
  Okimoto T, Kotani H, Iida Y, Koyanagi A, Tanino R, Tsubata Y, Isobe T, Harada M.
- Journal Title
  
  Cancer Sci.
  
  Volume: ー Issue: 6 Pages: 1910-1920
- DOI
  10.1111/cas.14401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-17K07217
[Journal Article] Different Sensitivities of Senescent Breast Cancer Cells to Immune Cell-Mediated Cytotoxicity2019
- Author(s)
  Inao T, Kotani H, Iida Y, Kartika ID, Okimoto T, Tanino R, Shiba E, Harada M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110(9) Issue: 9 Pages: 2690-2699
- DOI
  10.1111/cas.14116
- NAID
  120007002176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16393, KAKENHI-PROJECT-17K07217
[Journal Article] Bcl-2 inhibition sensitizes triple-negative humna breast cancer cells to doxorubicin.2018
- Author(s)
  Inao T, Iida Y, Moritani T, Okimoto T, Tanino R, Kotani H, Harada M.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 39 Pages: 25545-25556
- DOI
  10.18632/oncotarget.25370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07217, KAKENHI-PROJECT-16K15135
[Journal Article] Retinoic acid receptor agonist activity of naturally occurring diterpenes.2014
- Author(s)
  Hiroki Tanabe, Tomohisa Yasui, Hitoshi Kotani, Akito Nagatsu, Makoto Makishima, Sakae Amagaya, Makoto Inoue
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 22 Issue: 12 Pages: 3204-3212
- DOI
  10.1016/j.bmc.2014.03.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025, KAKENHI-PROJECT-25460132
[Journal Article] Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene.2014
- Author(s)
  Inoue M, Tanabe H, Nakashima K, Ishida Y, Kotani H.
- Journal Title
  
  J Nat Prod.
  
  Volume: 25;77(7) Issue: 7 Pages: 1670-7
- DOI
  10.1021/np5002016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460132, KAKENHI-PROJECT-26460134
[Journal Article] Retinoic acid receptor agonist activity of naturally occurring diterpenes2014
- Author(s)
  Tanabe Hiroki, Yasui Tomohiro, Kotani Hiroshi, Nagatsu Akito, Makishima Makoto, Amagaya Sakae, Inoue Makoto
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: vol.22 Pages: 3204-3212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590025
[Journal Article] CDK inhibitors suppress Th17 and promote iTreg differentiation, and ameliorate experimental autoimmune encephalomyelitis in mice.2013
- Author(s)
  Yoshida H, Kotani H, Kondo T, Tani I, Wei X, Tsuruta S, Kimura A, Asakawa M, Ito M, Nagai S, Yoshimura A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 435 Issue: 3 Pages: 378-384
- DOI
  10.1016/j.bbrc.2013.04.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790479, KAKENHI-PROJECT-25460132
[Journal Article] TRAF6 Is Essential for Maintenance of Regulatory T Cells That Suppress Th2 Type Autoimmunity.2013
- Author(s)
  Muto G, Kotani H, Kondo T, Morita R, Tsuruta S, Kobayashi, T., Luche H, Fehling HJ, Walsh M, Choi Y, Yoshimura A.
- Journal Title
  
  PLoS One
  
  Volume: 8 (9) Issue: 9 Pages: e74639-e74639
- DOI
  10.1371/journal.pone.0074639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590573, KAKENHI-PUBLICLY-24117718, KAKENHI-PROJECT-25460132, KAKENHI-PROJECT-25670234
[Journal Article] Preferential induction of Th17 cells in vitro and in vivo by Fucogalactan from Ganoderma lucidum (Reishi).2012
- Author(s)
  Yoshida H, Suzuki M, Sakaguchi R, Tani I, Kotani H, Shudo N, Yoshimura A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 25;422(1) Issue: 1 Pages: 174-80
- DOI
  10.1016/j.bbrc.2012.04.135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790754
[Journal Article] A Naturally Occurring Rexinoid, Honokiol, Can Serve as a Regulator of Various Retinoid X Receptor Heterodimers2012
- Author(s)
  Kotani H, Tanabe H, Mizukami H, Amagaya S, Inoue M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 1 Pages: 1-9
- DOI
  10.1248/bpb.35.1
- NAID
  130001872330
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] T 細胞分化制御活性を有する天然化合物の解析2023
- Author(s)
  小谷仁司, 片川和明, 矢作忠弘, 井上誠, 原田守
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K06950
[Presentation] ミャンマー産植物からのBMP/Smadシグナル活性成分の探索2022
- Author(s)
  矢作忠弘、渡辺美咲、今依麻、小谷仁司、松野倫代、川原信夫、松崎桂一
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] アカボシタツナミソウのBMP/Smadシグナル活性化成分の探索2022
- Author(s)
  渡辺美咲、福富遥都、矢作忠弘、上倉りな、三宅克典、小谷仁司、松崎桂一
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] エストロゲン受容体活性化作用を有する琉球弧植物の骨代謝への影響2022
- Author(s)
  渡辺美咲、福富遥都、矢作忠弘、三宅克典、小谷仁司、小川拓哉、松崎桂一
- Organizer
  日本薬学会第142年会（名古屋）
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] T 細胞分化制御活性を有する天然化合物の解析2022
- Author(s)
  小谷仁司, 矢作忠弘, 片川和明, 原田守
- Organizer
  日本生薬学会第68回年会
- Data Source
  KAKENHI-PROJECT-20K06950
[Presentation] エストロゲン受容体を標的とした骨形成促進作用を示す琉球弧植物の探索2021
- Author(s)
  渡辺美咲、矢作忠弘、白山貴大、三宅克典、小谷仁司、松﨑桂一
- Organizer
  日本生薬学会第67回年会（東京）
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] 老化誘導剤アフィジコリンと老化細胞除去薬ABT-263のヒト乳がんと肺がん細胞に対する併用効果2021
- Author(s)
  小谷仁司、谷野良輔、飯田雄一、原田守
- Organizer
  第80回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] 老化誘導剤アフィジコリンと老化細胞除去薬ABT-263による乳癌細胞に対する新しい組み合わせ治療2020
- Author(s)
  小谷仁司、飯田雄一、原田守
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] Identification of a candidate that suppresses the differentiation of naive helper T cells to regulatory T cells via screening of herbal crude drugs2019
- Author(s)
  Hitoshi Kotani, Yuichi Iida, Mamoru Harada
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16393
[Presentation] 免疫賦活作用を有する天然由来成分の探索と機能解析2018
- Author(s)
  小谷仁司、矢作忠弘、片川和明、飯田雄一、原田守
- Organizer
  日本生薬学会第65回年会
- Data Source
  KAKENHI-PROJECT-16K15135
[Presentation] 桂枝加朮附湯の骨芽細胞および破骨細胞に対する影響2018
- Author(s)
  渡辺美咲、矢作忠弘、小谷仁司、小川拓哉、古川めぐみ、松崎桂一
- Organizer
  日本生薬学会第65回年会
- Data Source
  KAKENHI-PROJECT-16K15135
[Presentation] 山豆根由来RXRアゴニスト活性成分の同定と機能解析2012
- Author(s)
  石田幸大中島健一田邉宏樹小谷仁司永津明人井上誠
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 山豆根由来ＲＸＲアゴニスト活性成分の同定と機能解析2012
- Author(s)
  石田幸大，中島健一，田邉宏樹，小谷仁司，永津明人，井上誠
- Organizer
  日本生薬学会第59回年会
- Place of Presentation
  かずさアカデミアパーク(千葉）
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] β-クリプトキサンチンによる脂肪細胞分化抑制の作用機序解析2011
- Author(s)
  田邊宏樹、小谷仁司、白倉義之、向井克之、井上誠
- Organizer
  日本生薬学会第58回年会
- Place of Presentation
  東京
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹、小谷仁司、安井友浩、野口教好、槇島　誠、井上　誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 生薬からの天然由来PPARδリガンドの探索と機能解析2011
- Author(s)
  小谷仁司，勝川千尋，中村知世，石田幸大，田邉宏樹，井上誠
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会２０１１
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 黄連含有イソキノリンアルカロイドの脂肪細胞分化抑制作用に関する機序解析2011
- Author(s)
  片桐由里絵，小谷仁司、田邉宏樹、井上　誠
- Organizer
  日本生薬学会第５８回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邊宏樹、小谷仁司、安井友浩、野口教好、槇島誠、井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 天然由来核内受容体RXRリガンドhonokiolによるヘテロダイマー活性化調節作用の検討2011
- Author(s)
  小谷仁司、田邉宏樹、水上　元、井上　誠
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹、小谷仁司、安井友浩、野口教好、槇島誠、井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-23590025
[Presentation] 生薬からの天然由来PPARδリガンドの探索と機能解析2011
- Author(s)
  小谷仁司勝川千尋中村知世石田幸大田邉宏樹井上誠
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2011
- Place of Presentation
  名古屋
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 漢方方剤繁用生薬由来レチノイン酸受容体アゴニストの探索と有用性の解析2011
- Author(s)
  田邉宏樹小谷仁司安井友浩野口教好槇島誠井上誠
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 黄連含有イソキノリンアルカロイドの脂肪細胞分化抑制作用に関する機序解析2011
- Author(s)
  片桐由里絵小谷仁司田邉宏樹井上誠
- Organizer
  日本生薬学会第58回年会
- Place of Presentation
  東京
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 天然由来核内受容体RXR リガンドhonokiolによるヘテロダイマー活性化調節作用の検討2011
- Author(s)
  小谷仁司田邉宏樹水上元井上誠
- Organizer
  第57回日本薬学会東海支部総会・大会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-09
- Data Source
  KAKENHI-PROJECT-23790754
[Presentation] 制御性T細胞の分化誘導を調節する生薬エキスのスクリーニング
- Author(s)
  小谷仁司　中川竜介　吉村昭彦　渡辺恵史
- Organizer
  日本生薬学会第61回年会
- Place of Presentation
  福岡大学薬学部
- Year and Date
  2014-09-13 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25460132

1. TANABE Hikoki (10415606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. INOUE Makoto (50191888)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. KATAKAWA Kazuaki (90433606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. NAGATSU Akito (70244572)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. MAKISHIMA Makoto (70346146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. YOSHIMURA Akihiko (90182815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. YAHAGI tadahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 原田守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 永井重徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 小林隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kotani Hitoshi 小谷 仁司

KOTANI Hitoshi 小谷 仁司

Research Projects

Research Products

Co-Researchers

ベンザインの位置選択的連続型環化反応を機軸とする生物活性アクリドンの合成研究

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Search for traditional drugs and naturally derived compounds that act on immune checkpoints and analyze their effectivenessPrincipal Investigator

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Natural-derived agonist search and activation mechanism analysis for nuclear receptor without ligand pocketPrincipal Investigator

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The search and functional analysis of the natural compound promoting the differentiation of regulatory T cells.Principal Investigator

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Search for naturally occurring retinoic acid receptor agonists and thier application to immune and allergic diseases

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Clarify the meaning of Magnolia obovata in Kampo medicine on nuclear receptor activation.Principal Investigator

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[Journal Article] T-cell responses and combined immunotherapy against human carbonic anhydrase 9-expressing mouse renal cell carcinoma2021

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[Journal Article] Protective role of cytoplasmic p21Cip1/Waf1 in apoptosis of CDK4/6 inhibitor‐induced senescence in breast cancer cells2021

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[Journal Article] Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells2020

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[Journal Article] Immunogenic chemotherapy in two mouse colon cancer models2020

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[Journal Article] Supplementation of l ‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy2020

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[Journal Article] Pemetrexed Sensitizes Human Lung Cancer Cells to Cytotoxic Immune Cells2020

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[Journal Article] Different Sensitivities of Senescent Breast Cancer Cells to Immune Cell-Mediated Cytotoxicity2019

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NAID

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[Journal Article] Bcl-2 inhibition sensitizes triple-negative humna breast cancer cells to doxorubicin.2018

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Kotani Hitoshi 小谷仁司

KOTANI Hitoshi 小谷仁司