Ikenuma Hiroshi 池沼宏

Researcher Number	10751159
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 研究技術員
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 研究技術員 2020 – 2021: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 研究技術員 2018 – 2019: 国立研究開発法人国立長寿医療研究センター, その他部局等, 研究技術員
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic Section 52040:Radiological sciences-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator GPR40 / PET / FFAR1 / PETイメージング Except Principal Investigator 陽電子断層撮像法 / ミクログリア / アルツハイマー病 / PET / CSF1R / IEDDA … More / 細胞トラッキング / 生体直交反応 / コロニー刺激因子１ / Alzheimer's disease / microglia / RIPK1 / 神経炎症 / マイクログリア / 陽電子断層撮像 Less

Evaluation of a PET imaging ligand for microglia in Alzheimer's diseases
- Principal Investigator
  
  木村泰之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Development of an in vivo cell tracking method using biological orthogonal reactions and PET
- Principal Investigator
  
  木村泰之
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
膵臓β細胞および脳に発現する遊離脂肪酸受容体を標的とした新規PETプローブの創製Principal Investigator
- Principal Investigator
  
  池沼宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
Development of PET imaging of brain immunity as a biomarker for drug development to treat neurodegenerative diseases
- Principal Investigator
  
  KIMURA YASUYUKI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology
PET imaging of microglia, a novel drug target for neurodegenerative diseases
- Principal Investigator
  
  Kimura Yasuyuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center for Geriatrics and Gerontology

All 2023 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Synthesis and evaluation of a novel PET ligand, a GSK’963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain2023
- Author(s)
  Ikenuma Hiroshi、Ogata Aya、Koyama Hiroko、Ji Bin、Ishii Hideki、Yamada Takashi、Abe Junichiro、Seki Chie、Nagai Yuji、Ichise Masanori、Minamimoto Takafumi、Higuchi Makoto、Zhang Ming-Rong、Kato Takashi、Ito Kengo、Suzuki Masaaki、Kimura Yasuyuki
- Journal Title
  
  EJNMMI Radiopharmacy and Chemistry
  
  Volume: 8 Issue: 1 Pages: 31-31
- DOI
  10.1186/s41181-023-00217-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02876, KAKENHI-PROJECT-23K27558
[Journal Article] Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain2023
- Author(s)
  Ogata Aya、Yamada Takashi、Hattori Saori、Ikenuma Hiroshi、Abe Junichiro、Tada Mari、Ichise Masanori、Suzuki Masaaki、Ito Kengo、Kato Takashi、Amaike Kazuma、Hirota Tsuyoshi、Kakita Akiyoshi、Itami Kenichiro、Kimura Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 90 Pages: 129327-129327
- DOI
  10.1016/j.bmcl.2023.129327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21269, KAKENHI-PROJECT-21H02876
[Journal Article] [11C]NCGG401, a novel PET ligand for imaging of colony stimulating factor 1 receptors2022
- Author(s)
  Ogata Aya、Ji Bin、Yamada Takashi、Hattori Saori、Abe Junichiro、Ikenuma Hiroshi、Ichise Masanori、Koyama Hiroko、Suzuki Masaaki、Kato Takashi、Ito Kengo、Kimura Yasuyuki
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 65 Pages: 128704-128704
- DOI
  10.1016/j.bmcl.2022.128704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] ミクログリア特異的に発現するCSF1Rを標的とした新規脳PET製剤[11C]NCGG401のFirst in human　試験2023
- Author(s)
  小縣　綾、池沼　宏、二橋尚志、安野忠彦、市瀬正則、服部沙織、佐藤弥生、森下　浩、伊藤健吾、加藤隆司、木村泰之
- Organizer
  第63回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] First-in-Human PET imaging of [11C]NCGG401 for colony-stimulating factor 1 receptor.2022
- Author(s)
  Ogata A, Ikenuma H, Nihashi T, Yasuno F, Morishita H, Abe J, Ichise M, Kato T, Ito K, Kimura Y.
- Organizer
  The 13th Congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] Development of a novel PET ligand for receptor-interacting protein kinase 1 in brain2021
- Author(s)
  Ikenuma H, Ogata A, Koyama H, Yamada T, Abe J, Ichise M, Kato T, Suzuki M, Ito K, Kimura Y
- Organizer
  NRM 2021 MAPPING NEURORECEPTORS AT WORK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] RIPK1を標的とした新規ＰＥＴリガンド開発の試みと有効性の評価2021
- Author(s)
  池沼　宏、古山浩子、小懸綾、季斌、山田貴史、永井裕司、阿部潤一郎、市瀬正則、加藤隆司、鈴木正昭、木村泰之
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] Development of novel PET ligands to image the Receptor Interacting Protein Kinase 12021
- Author(s)
  Sakai T, Yamada T, Ikenuma H, Ogata A, Ichise M, Hattori S, Abe J, Suzuki M, Ito K, Kato T, Imamura S, Kimura Y
- Organizer
  NRM 2021 MAPPING NEURORECEPTORS AT WORK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] PET imaging of [11C]NCGG401 for colony stimulating factor 1 receptor2021
- Author(s)
  Ogata A, Yamada T, Abe J, Ichise M, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K, Kimura Y
- Organizer
  NRM 2021 MAPPING NEURORECEPTORS AT WORK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02876
[Presentation] Colony stimulating factor 1 receptorを標的としたミクログリア特異的PETイメージングの開発2019
- Author(s)
  小縣綾、木村泰之、山田貴史、市瀬正則、阿部潤一郎、池沼宏、古山浩子、鈴木正昭、加藤隆司、伊藤健吾
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains.2019
- Author(s)
  Ogata A, Kimura Y, Yamada T, Ichise M, Ikenuma H, Abe J, Koyama H, Suzuki M, Kato T, Ito K.
- Organizer
  Brain & Brain PET 2019,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] The evaluation of a novel PET ligand for colony stimulating factor 1 receptor in status epilepticus model rat brains.2018
- Author(s)
  Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
- Organizer
  nnual Congress of the European Association of Nuclear Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776
[Presentation] Development of PET imaging of Colony Stimulating Factor 1 Receptor Expressed on Microglia.2018
- Author(s)
  Ogata A, Kimura Y, Yamada T, Bin Ji, Seki C, Ichise M, Abe J, Ikenuma H, Koyama H, Suzuki M, Kato T, Ito K
- Organizer
  The XII International Symposium of Functional Neuroreceptor Mapping of the Living Brain
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02776

1. Kimura Yasuyuki (20423171)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. 小縣綾 (10805857)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. 古山浩子 (50402160)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. 加藤隆司 (60242864)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
5. 外山宏 (90247643)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. 境崇行 (40881925)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. 季斌 (80392223)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. 今村真一 (40873203)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 安野史彦 (60373388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 鈴木弘美 (30340269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 鈴木正昭 (90093046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 二橋尚志 (00426496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 横井克典 (30899737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 百田洋之 (60469971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 錦見昭彦 (70404019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 廣田毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ikenuma Hiroshi 池沼 宏

Research Projects

Research Products

Co-Researchers

Evaluation of a PET imaging ligand for microglia in Alzheimer's diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an in vivo cell tracking method using biological orthogonal reactions and PET

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膵臓β細胞および脳に発現する遊離脂肪酸受容体を標的とした新規PETプローブの創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of PET imaging of brain immunity as a biomarker for drug development to treat neurodegenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PET imaging of microglia, a novel drug target for neurodegenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Synthesis and evaluation of a novel PET ligand, a GSK’963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a novel PET ligand, [11C]GO289 targeting CK2 expressed in the brain2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] [11C]NCGG401, a novel PET ligand for imaging of colony stimulating factor 1 receptors2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] ミクログリア特異的に発現するCSF1Rを標的とした新規脳PET製剤[11C]NCGG401のFirst in human 試験2023

Author(s)

Organizer

Data Source

[Presentation] First-in-Human PET imaging of [11C]NCGG401 for colony-stimulating factor 1 receptor.2022

Author(s)

Organizer

Data Source

[Presentation] Development of a novel PET ligand for receptor-interacting protein kinase 1 in brain2021

Author(s)

Organizer

Data Source

[Presentation] RIPK1を標的とした新規ＰＥＴリガンド開発の試みと有効性の評価2021

Author(s)

Organizer

Data Source

[Presentation] Development of novel PET ligands to image the Receptor Interacting Protein Kinase 12021

Author(s)

Organizer

Data Source

[Presentation] PET imaging of [11C]NCGG401 for colony stimulating factor 1 receptor2021

Author(s)

Organizer

Data Source

[Presentation] Colony stimulating factor 1 receptorを標的としたミクログリア特異的PETイメージングの開発2019

Author(s)

Organizer

Data Source

[Presentation] PET imaging of colony stimulating factor 1 receptor in rat brains.2019

Author(s)

Organizer

Ikenuma Hiroshi 池沼宏

[Presentation] ミクログリア特異的に発現するCSF1Rを標的とした新規脳PET製剤[11C]NCGG401のFirst in human　試験2023