• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Aoki Miho  粟生木 美穂

ORCIDConnect your ORCID iD *help
… Alternative Names

粟生木 美穂  アオキ ミホ

Less
Researcher Number 10783227
Affiliation (Current) 2025: 福島県立医科大学, 公私立大学の部局等, 助手
Affiliation (based on the past Project Information) *help 2023: 福島県立医科大学, 公私立大学の部局等, 助手
2016 – 2021: 福島県立医科大学, 公私立大学の部局等, 助手
Review Section/Research Field
Principal Investigator
Radiation science
Except Principal Investigator
Basic Section 52040:Radiological sciences-related
Keywords
Principal Investigator
加速器 / 核医学 / 放射線、X線、粒子線 / 前立腺がん / α線 / 放射性薬剤 / 分析科学 / 放射線 / 内用放射線治療 / 癌 / GRP受容体 / ペプチド … More
Except Principal Investigator
… More アスタチン / アスタチン-211 / RI内用療法 / 核医学治療 / ドジメトリー / アビジン / ビオチン / α線 / アイソトープ治療 / プレターゲティング / 癌 / 治療用放射性薬剤 / チミジンホスホリラーゼ / 抗CD82抗体 / 急性骨髄性白血病 / α線放出核種 / アスタチン-211標識抗体 / ヒト化白血病モデルマウス / 抗hCD82ヒト化キメラmAb / 急性白血病 / 白血病幹細胞 / アルファ線標的治療 / CD82抗原 / アルファ線 / 内用療法 / イメージング / ペプチド / プローブ / セラノスティクス / がん / 核医学 Less
  • Research Projects

    (5 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (17 People)
  •  Development of an innovative leukemia therapy using alpha-particle-emitting nuclides targeting cancer stem cells

    • Principal Investigator
      ZHAO Songji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Fukushima Medical University
  •  Optimization of pretargeted alpha therapy for multiple types of cancer

    • Principal Investigator
      Washiyama Kohshin
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Fukushima Medical University
  •  PD-ECGF targeted tumor treatment with new At-211 radiolabeled uracil derivatives

    • Principal Investigator
      NISHIJIMA Ken-ichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Fukushima Medical University
  •  Establishment of comprehensive cancer diagnosis and therapy using radio halogen

    • Principal Investigator
      OGAWA KAZUMA
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kanazawa University
  •  Investigation for diagnosis and treatment of prostate cancer using radiohalogen labeled Bombesin derivativePrincipal Investigator

    • Principal Investigator
      Aoki Miho
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Radiation science
    • Research Institution
      Fukushima Medical University

All 2023 2022 2021 2020 2019 2017

All Journal Article Presentation

  • [Journal Article] Preliminary Evaluation of Astatine-211-Labeled Bombesin Derivatives for Targeted Alpha Therapy2020

    • Author(s)
      Aoki Miho、Zhao Songji、Takahashi Kazuhiro、Washiyama Kohshin、Ukon Naoyuki、Tan Chengbo、Shimoyama Saki、Nishijima Ken-ichi、Ogawa Kazuma
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 68 Issue: 6 Pages: 538-545

    • DOI

      10.1248/cpb.c20-00077

    • NAID

      130007850061

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2020-06-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-18K07630
  • [Journal Article] Human dosimetry of free 211At and meta-[211At]astatobenzylguanidine (211At-MABG) estimated using preclinical biodistribution from normal mice2020

    • Author(s)
      Ukon Naoyuki、Zhao Songji、Washiyama Kohshin、Oriuchi Noboru、Tan Chengbo、Shimoyama Saki、Aoki Miho、Kubo Hitoshi、Takahashi Kazuhiro、Ito Hiroshi
    • Journal Title

      EJNMMI Physics

      Volume: 7 Issue: 1 Pages: 58-58

    • DOI

      10.1186/s40658-020-00326-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-19H03605, KAKENHI-PROJECT-18K15556, KAKENHI-PROJECT-20H03627
  • [Journal Article] Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using 211At-CXCR4 monoclonal antibody.2020

    • Author(s)
      Oriuchi N
    • Journal Title

      Sci. Rep.

      Volume: 10 Issue: 1 Pages: 6810-6810

    • DOI

      10.1038/s41598-020-63557-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H03548, KAKENHI-PROJECT-19K08180, KAKENHI-PROJECT-20K08031, KAKENHI-PROJECT-20K21582, KAKENHI-PROJECT-19H03605
  • [Presentation] Pretargeted alpha radioimmunotherapy for the treatment of gastric cancer using low-immunogenic mutated streptavidin and 211At labeled modified bis-iminobiotin2023

    • Author(s)
      Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      12th International Symposium on Targeted Alpha Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] Synthesis of an 211At labelled bis-iminobiotin derivativewith enhanced plasma stability2022

    • Author(s)
      Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      2022 JSNM Annual Meeting
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] Synthesis and evaluation of 211At-labeled bis-iminobiotin for pretargeted alpha radioimmunotherapy2022

    • Author(s)
      Kohshin Washiyama, Toshifumi Tatsumi, Akira Sugiyama, Songji Zhao, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      2022 SNMMI Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] [211At]MABG注射液の品質試験:LCMSを用いた確認試験法の開発2021

    • Author(s)
      西嶋 剣一、粟生木 美穂、城寶 大輝、鷲山 幸信、佐々木 茂範、望月 一優、塩入 大護、髙橋 和弘
    • Organizer
      日本薬学会 第141年会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] Targeted delivery of 211At with low immunogenic mutant streptavidin-bisiminobiotin pre-targeting system2021

    • Author(s)
      Toshifumi Tatsumi, Kenzo Yamatsugu, Akira Sugiyama, Songji Zhao, Miho Aoki, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Fengying Gao, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] Feasibility of cancer stem cells-targeted radioimmunotherapy for acute myelogenous leukemia with 211At-CXCR4 monoclonal antibody.2020

    • Author(s)
      Oriuchi N, Aoki M, Ukon N, Washiyama K, Shimoyama S, Nishijima K, Takahashi K, Ito H, Ikezoe K, Zhao S
    • Organizer
      2020米国核医学・分子イメージング学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] イミノビオチン誘導体の合成とアスタチン標識の検討2020

    • Author(s)
      粟生木美穂, 巽俊文, 西嶋剣一, 山次健三, 城寶大輝, 趙松吉, 杉山暁, 児玉龍彦, 高橋和弘, 金井求, 鷲山幸信
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] プレターゲティングへの応用を目指した211At標識改変イミノビオチンの体内分布測定2020

    • Author(s)
      鷲山幸信, 巽俊文, 杉山暁, 粟生木美穂, 譚成博, 下山彩希, 山次健三, 金井求, 児玉龍彦, 趙松吉, 高橋和弘
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] コンパニオン診断薬としての123I-MIBGから推定した211At-MABGの線量評価検討2020

    • Author(s)
      右近直之, 趙松吉, 鷲野弘明, 吉永恵一郎, 粟生木美穂, 西嶋剣一, 鷲山幸信, 織内昇, 高橋和弘, 東達也, 伊藤浩
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] Development of a pre-targeting strategy of low-immunogenic mutated streptavidin with 211At labeled modified biotin for advanced cancer treatment2020

    • Author(s)
      Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Naoyuki Ukon, Saki Shimoyama, Chengbo Tan, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      SNMMI 2020 Annual Meeting - Virtual Edition
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] 色細胞腫モデルにおける211At-MABGと 131I-MIBGの抗腫瘍効果および暗線性の比較2020

    • Author(s)
      Yoshinaga K, Zhao S, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] Search for the optimal bis-iminobiotin for the pretargeting strategy using a mutated low immunogenic streptavidin2020

    • Author(s)
      K. Washiyama, T. Tatsumi, S. Zhao, A. Sugiyama, M. Aoki, K. Yamatsugu, N. Ukon, K. Nishijima, S. Shimoyama, C. Tan, T. Joho, N. Oriuchi, M. Kanai, K. Takahashi, T. Kodama
    • Organizer
      33th Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] Biodistribution and dosimetry studies for the optimization of pre-targeted radionuclide therapy using 211At-labeled modified biotin2020

    • Author(s)
      Kohshin Washiyama, Akira Sugiyama, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Kenzo Yamatsugu, Ken-ichi Nishijima, Saki Shimoyama, Taiki Joho, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      33th Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] α放射体211At標識イミノビオチンの作成と安定性評価2020

    • Author(s)
      鷲山幸信、粟生木美穂、巽俊文、山次健三、杉山暁、西嶋剣一、城寶大輝、高峰英、趙松吉、金井求、児玉龍彦、高橋和弘
    • Organizer
      日本放射化学会第64回討論会(2020)
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] 進行がん治療を指向した低免疫原性ストレプトアビジン変異体と 211At標識イミノビオチンを用いるプレターゲティングシステムの開発2020

    • Author(s)
      巽俊文, 山次健三, 清水洋平, 杉山暁, 趙松吉, 粟生木美穂, 西嶋剣一, 右近直之, 高橋和弘, 児玉龍彦, 鷲山幸信, 金井求
    • Organizer
      反応と合成の進歩2020特別企画シンポジウム|
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] 正常マウスにおける211At-MABGの 血液毒性の用量反応関係2020

    • Author(s)
      鷲野弘明, 趙 松吉, 下山彩希, 吉岡菜穂, 伊東奈津江, 粟生木美穂, 右近直之, 吉永恵一郎, 高橋和弘, 伊藤 浩, 東 達也
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] α放射体211Atを用いたプレターゲティング法による進行がんの治療2020

    • Author(s)
      Kohshin Washiyama, Akira Sugiyama, Kenzo Yamatsugu, Songji Zhao, Toshifumi Tatsumi, Miho Aoki, Naoyuki Ukon, Saki Shimoyama, Ken-ichi Nishijima, Chengbo Tan, Taiki Joho, Fengying Gao, Noboru Oriuchi, Motomu Kanai, Kazuhiro Takahashi, Tatsuhiko Kodama
    • Organizer
      日本放射線影響学会第63回大会
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] Effects and safety of alpha-emitting meta-211At-astato-benzylguanidine (211At-MABG) compared with 131I-meta-iodobenzylguanidine (131I-MIBG) on tumor growth suppression in a pheochromocytoma mouse model.2020

    • Author(s)
      Zhao S, Yoshinaga K, Washino K, Aoki M, Nishijima K, Shimoyama S, Ukon N, Gao F, Washiyama K, Ito N, Yoshioka N, Tamura N, Takahashi K, Higashi T, Ito H
    • Organizer
      2020米国核医学・分子イメージング学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] 正常マウスにおける211At-MABGの毒性評価2020

    • Author(s)
      趙松吉, 吉永恵一郎, 粟生木美穂, 右近直之, 下山彩希, 西嶋剣一, 鷲山幸信, 鷲野弘明, 高橋和弘, 東達也, 伊藤浩
    • Organizer
      第60回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] Evaluation of therapeutic effect of the targeted alpha therapy using Cupid-211At-labeled Psyche-B pretargeting system in a human gastric cancer cell xenograft2020

    • Author(s)
      Songji Zhao, Akira Sugiyama, Naoyuki Ukon, Saki Shimoyama, Toshifumi Tatsumi, Miho Aoki, Fengying Gao, Kenzo Yamatsugu, Ken-ichi Nishijima, Taiki Joho, Noboru Oriuchi, Kazuhiro Takahashi, Motomu Kanai, Tatsuhiko Kodama, Kohshin Washiyama
    • Organizer
      33th Annual Congress of the European Association of Nuclear Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03627
  • [Presentation] 211At-MABG吸収線量評価におけるコンパニオン診断薬123I-MIBGの活用 核医学2019

    • Author(s)
      吉永 恵一郎, 趙 松吉, 粟生木 美穂, 右近 直之, 下山 彩希, 西嶋 剣一, 鷲山 幸信, 鷲野 弘明, 高橋 和弘, 伊藤 浩, 東 達也
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] Synthesis of [211At]MABG Using Remote-controlled Synthesizer and Quality Evaluation2019

    • Author(s)
      M. Aoki, K. Minegishi, K. Nishijima, H. Suzuki, S. Sasaki, K. Washiyama, S. Zhao, K. Nagatsu, M. Zhang, K. Takahashi
    • Organizer
      The 23rd International Symposium on Radiopharmaceutical Sciences
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] 正常マウスにおける123I-MIBGと211At-MABGの体内動態の評価2019

    • Author(s)
      趙 松吉, 吉永 恵一郎, 粟生木 美穂, 右近 直之, 下山 彩希, 西嶋 剣一, 鷲山 幸信, 鷲野 弘明, 高橋 和弘, 東 達也, 伊藤 浩
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] 211At標識抗CXCR4抗体の腫瘍移植マウスにおける体内分布2019

    • Author(s)
      織内 昇, 趙 松吉, 粟生木 美穂, 譚 成博, 右近 直之, 西嶋 剣一, 鷲山 幸信, 高橋 和弘, 池添 隆之, 伊藤 浩
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] 小動物用SPECT装置を用いた211Atによる画像化の基礎検討2019

    • Author(s)
      右近 直之, 趙 松吉, 鷲山 幸信, 織内 昇, 粟生木 美穂, 西嶋 剣一, 譚 成博, 下山 彩希, 久保 均, 高橋 和弘, 伊藤 浩
    • Organizer
      第14回日本分子イメージング学会学術総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] 正常マウスにおける211At-MABGの薬物動態と代謝産物の予備的評価2019

    • Author(s)
      鷲野 弘明, 趙 松吉, 粟生木 美穂, 右近 直之, 下山 彩希, 西嶋 剣一, 鷲山 幸信, 吉永 恵一郎, 高橋 和弘, 伊藤 浩, 東 達也
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] [211At]MABGの薄層クロマトグラフィー手順の探索2019

    • Author(s)
      粟生木 美穂, 西嶋 剣一, 鷲山 幸信, 城寶 大輝, 下山 彩希, 右近 直之, 趙 松吉, 鷲野 弘明, 高橋 和弘, 東 達也, 伊藤 浩
    • Organizer
      第59回日本核医学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08180
  • [Presentation] The Production of 211At at Fukushima Medical University2017

    • Author(s)
      Aoki Miho, Tominaga Hideyuki, Kato Jun, Oda Takashi, Zhao Songji, Hiasa Toshikazu, Oriuchi Noboru, Seiichi Takenoshita
    • Organizer
      10th International Symposium on Targeted Alpha Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H07099
  • 1.  ZHAO Songji (80374239)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 26 results
  • 2.  OGAWA Kazuma (30347471)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NISHIJIMA Ken-ichi (60364254)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 4.  Washiyama Kohshin (80313675)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 5.  高橋 和弘 (20370257)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 6.  杉山 暁 (40562715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 7.  右近 直之 (70792985)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 8.  三代 憲司 (60776079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  池添 隆之 (80294833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  織内 昇 (40292586)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  東川 桂 (10756878)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  久下 裕司 (70321958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  山下 雄史 (50615622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  横山 明彦 (80230655)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  巽 俊文 (80868232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 13 results
  • 16.  ITO Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  久保 均
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi