kobayashi masanori 小林正典

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Kobayashi Masanori 小林正典

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Researcher Number	10825459
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2022: 東京医科歯科大学, 医学部附属病院, 助教 2021: 東京医科歯科大学, 東京医科歯科大学病院, 特任助教 2019 – 2021: 東京医科歯科大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields
Keywords	Principal Investigator 網羅的遺伝子解析 / オルガノイド / 膵充実性偽乳頭腫瘍 / 発癌機序 / 胆汁 / iPS細胞 / 胆管上皮細胞 / 疾患モデル / 胆管癌 / ヒトiPS細胞 … More Except Principal Investigator … More RNAーseq / NEC / NET / RNA -seq / pan-NEN / RNA-seq / 網羅的遺伝子発現解析 / 膵オルガノイド / 肝転移 / 膵神経内分泌腫瘍 Less

オルガノイド培養系を用いた膵充実性偽乳頭腫瘍の成立・悪性化機序の解明Principal Investigator
- Principal Investigator
  
  小林正典
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of molecular characteristics and metastatic mechanism of Pancreatic neuroendocrine neoplasm.
- Principal Investigator
  
  Ito Go
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Tokyo Medical and Dental University
Analysis of a novel molecular mechanism in bile duct carcinoma using a human iPS cell-derived cholangiocyte culture systemPrincipal Investigator
- Principal Investigator
  
  Kobayashi Masanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024
- Author(s)
  Ogasawara N, Kano Y, Yoneyama Y, Kobayashi S, Watanabe S, Kirino S, Velez-Bravo FD, Hong Y, Ostapiuk A, Lutsik P, Onishi I, Yamauchi S, Hiraguri Y, Ito G, Kinugasa Y, Ohashi K, Watanabe M, Okamoto R, Tejpar S, Yui S.
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 3 Pages: 109247-109247
- DOI
  10.1016/j.isci.2024.109247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-23K07394, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-23K27578
[Journal Article] Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment2023
- Author(s)
  Watanabe Satoshi、Ogasawara Nobuhiko、Kobayashi Sakurako、Kirino Sakura、Inoue Masami、Hiraguri Yui、Nagata Sayaka、Shimizu Hiromichi、Ito Go、Mizutani Tomohiro、Nemoto Yasuhiro、Tsuchiya Kiichiro、Okamoto Ryuichi、Watanabe Mamoru、Yui Shiro
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 58 Issue: 4 Pages: 379-393
- DOI
  10.1007/s00535-023-01959-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08048, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-21H02898, KAKENHI-PROJECT-23K07394, KAKENHI-PROJECT-22K19519, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23K27578
[Journal Article] A convenient and reliable method for endoscopic mapping biopsy of cholangiocarcinoma using a double-lumen cytology device.2022
- Author(s)
  Kobayashi Masanori、Ryozawa Shomei、Ohtsuka Kazuo、Tanabe Minoru、Okamoto Ryuichi
- Journal Title
  
  VideoGIE
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08461
[Journal Article] Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation2022
- Author(s)
  Kobayashi S, Ogasawara N, Watanabe S, Yoneyama Y, Kirino S, Hiraguri Y, Inoue M, Nagata S, Okamoto-Uchida Y, Kofuji S, Shimizu H, Ito G, Mizutani T, Yamauchi S, Kinugasa Y, Kano Y, Nemoto Y, Watanabe M, Tsuchiya K, Nishina H, Okamoto R, Yui S.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 42 Issue: 1 Pages: 49-49
- DOI
  10.1186/s41232-022-00237-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06544, KAKENHI-PROJECT-22K06923, KAKENHI-PROJECT-22K08048, KAKENHI-PROJECT-22K09680, KAKENHI-PROJECT-21KK0146, KAKENHI-PROJECT-22H00472, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-20H03657, KAKENHI-PROJECT-21H02895, KAKENHI-PROJECT-21H02898
[Journal Article] Caenorhabditis elegans as a Diagnostic Aid for Pancreatic Cancer2021
- Author(s)
  Kobayashi Masanori、Fujita Akashi、Ogawa Tomoya、Tanisaka Yuki、Mizuide Masafumi、Kondo Nobuaki、Imaizumi Yuki、Hirotsu Takaaki、Ryozawa Shomei
- Journal Title
  
  Pancreas
  
  Volume: 50 Issue: 5 Pages: 673-678
- DOI
  10.1097/mpa.0000000000001814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08461
[Journal Article] Caenorhabditis Elegans/ as a Diagnostic Aid for Pancreatic Cancer2021
- Author(s)
  Kobayashi M, Fujita A, Ogawa T, Yanisaka Y, Mizuide M, Kondo N, Imaizumi Y, Hirotsu T, Ryozawa S
- Journal Title
  
  Pancreas
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08461
[Journal Article] A rare case of hepatocellular carcinoma with bile duct invasion diagnosed by peroral cholangioscopy2021
- Author(s)
  Ito Risako、Kobayashi Masanori、Ohtsuka Kazuo、Tanabe Minoru、Okamoto Ryuichi
- Journal Title
  
  VideoGIE
  
  Volume: 6 Issue: 8 Pages: 354-357
- DOI
  10.1016/j.vgie.2021.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08461
[Journal Article] Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells.2020
- Author(s)
  Otsubo K, Maeyashiki C, Nibe Y, Tamura A, Aonuma E, Matsuda H, Kobayashi M, Onizawa M, Nemoto Y, Nagaishi T, Okamoto R, Tsuchiya K, Nakamura T, Torii S, Itakura E, Watanabe M, Oshima S.
- Journal Title
  
  FEBS letters
  
  Volume: 594 Issue: 10 Pages: 1586-1595
- DOI
  10.1002/1873-3468.13748
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K08364, KAKENHI-PROJECT-19K22413, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-16H06167, KAKENHI-PROJECT-17K09372, KAKENHI-PROJECT-19K08388, KAKENHI-PROJECT-19K08438, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-20H03658, KAKENHI-PROJECT-18K07934, KAKENHI-PROJECT-19K17426, KAKENHI-PROJECT-17H04024, KAKENHI-PROJECT-17K19675
[Journal Article] Colorectal and gastric metastases from lobular breast cancer that resembled superficial neoplastic lesions2020
- Author(s)
  Kobayashi Masanori、Tashima Tomoaki、Nagata Koji、Sakuramoto Shinichi、Osaki Akihiko、Ryozawa Shomei
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 14 Issue: 1 Pages: 103-108
- DOI
  10.1007/s12328-020-01285-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08461
[Journal Article] Investigation of Factors Affecting the Sensitivity of Bile Duct Brush Cytology2019
- Author(s)
  Kobayashi Masanori、Ryozawa Shomei、Araki Ryuichiro、Nagata Koji、Tanisaka Yuki、Fujita Akashi、Kobatake Tsutomu
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 3 Pages: 329-335
- DOI
  10.2169/internalmedicine.1551-18
- NAID
  130007590231
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08384, KAKENHI-PROJECT-19K08461
[Journal Article] The usefulness of wire-guided endoscopic snare papillectomy for tumors of the major duodenal papilla2019
- Author(s)
  Kobayashi Masanori、Ryozawa Shomei、Iwano Hirotoshi、Araki Ryuichiro、Tanisaka Yuki、Fujita Akashi、Kobatake Tsutomu
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 1 Pages: e0211019-e0211019
- DOI
  10.1371/journal.pone.0211019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] Analysis of gene expression to elucidate the pathogenesis of pancreatic solid pseudopapillary neoplasm.2023
- Author(s)
  Katsuda H, Ito G, Hiraguri Y, Muto T, Ishido S, Kobayashi M, Yamashita H, Ito A, Ono H, Kudo A, Watanabe M, Tanabe M, Okamoto R
- Organizer
  UEGW2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0146
[Presentation] 高齢者IPMNの手術適応判断おける嚢胞径と主膵管拡張の意義2023
- Author(s)
  小林正典, 田邉稔, 岡本隆一
- Organizer
  第109回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-22K08029
[Presentation] Analysis of molecular characteristics and metastatic mechanism of pancreatic neuroendocrine neoplasms.2022
- Author(s)
  Ryota Kuribayashi, Go Ito, Neha Mishra, Yui Hiraguri, Hiromune Katsuda, Masanori Kobayashi, Tomohiro Muto, Hironari Yamashita, Atsushi Kudo,Minoru Tanabe, Konrad Aden, Philip Rosenstiel,Mamoru Watanabe, Ryuichi Okamoto
- Organizer
  International Syscid Symposium, 2022.Kiel, Germany
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0146
[Presentation] 膵SPNの病態解明にむけた集学的解析2022
- Author(s)
  小林正典, 伊藤剛, 申貴広, 山下宏成, 工藤篤, 田邉稔, 岡本隆一
- Organizer
  第64回　日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-21KK0146
[Presentation] 膵SPNの病態解明にむけた集学的解析2022
- Author(s)
  小林正典, 伊藤剛, 申貴広, 山下宏成, 工藤篤, 田邉稔, 岡本隆一
- Organizer
  第64回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-22K08029
[Presentation] 膵神経内分泌腫瘍のgradingにおける超音波内視鏡下穿刺生検の有用性の検討2021
- Author(s)
  小林正典, 大塚和朗, 桐村進, 工藤篤, 田邉稔, 岡本隆一
- Organizer
  第101回消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] The usefulness of endoscopic ultrasound-fine needle aspiration in the grading of pancreatic neuroendocrine neoplasms2021
- Author(s)
  Kobayashi M, Ohtsuka K, Kirimura S, Tanabe M, Okamoto R.
- Organizer
  APDW2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] 当院におけるIPMN診断治療の現状2020
- Author(s)
  小林正典，大塚和朗，伴大輔，田邉稔
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] IPMN術前精査における超音波内視鏡検査の役割2020
- Author(s)
  小林正典，大塚和朗，田邉稔
- Organizer
  JDDW2020
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] 当院におけるEST後出血への対応2020
- Author(s)
  小林正典，大塚和朗，土屋輝一郎
- Organizer
  第99回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] Effectiveness of Endoscopic Ultrasonography-Guided Fine-Needle Aspiration for the Diagnosis of Pancreatic Neuroendocrine Tumors2019
- Author(s)
  Masanori Kobayashi, Kazuo Ohtsuka, Daisuke Ban, Atsushi Kudo, Minoru Tanabe
- Organizer
  American Pancreatic Association 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] 総胆管に穿破した主膵管型IPMNの1例2019
- Author(s)
  小林正典，大塚和朗，小川康介，伴大輔，田邉稔
- Organizer
  第55回胆道学会総会
- Data Source
  KAKENHI-PROJECT-19K08461
[Presentation] 胆管カニュレーション困難症例に対する細胞診ブラシのカニュラへの応用2019
- Author(s)
  小林正典，谷坂優樹，水出雅文，良沢昭銘，大塚和朗，渡辺守
- Organizer
  第97回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-19K08461

1. Ito Go (20733900)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 田邉稔 (50197513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 岡本隆一 (50451935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 柿沼晴 (30372444)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 土屋輝一郎 (40376786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 大島茂 (50376787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 工藤篤 (20376734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. TORII Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. KOFUJI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田辺稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
11. 小林真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 米山鷹介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kobayashi masanori 小林 正典

Kobayashi Masanori 小林 正典

Research Projects

Research Products

Co-Researchers

オルガノイド培養系を用いた膵充実性偽乳頭腫瘍の成立・悪性化機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular characteristics and metastatic mechanism of Pancreatic neuroendocrine neoplasm.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of a novel molecular mechanism in bile duct carcinoma using a human iPS cell-derived cholangiocyte culture systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Organoids transplantation as a new modality to design epithelial signature to create a membrane-protective sulfomucin-enriched segment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A convenient and reliable method for endoscopic mapping biopsy of cholangiocarcinoma using a double-lumen cytology device.2022

Author(s)

Journal Title

Data Source

[Journal Article] Collagen type I-mediated mechanotransduction controls epithelial cell fate conversion during intestinal inflammation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Caenorhabditis elegans as a Diagnostic Aid for Pancreatic Cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Caenorhabditis Elegans/ as a Diagnostic Aid for Pancreatic Cancer2021

Author(s)

Journal Title

Data Source

[Journal Article] A rare case of hepatocellular carcinoma with bile duct invasion diagnosed by peroral cholangioscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Receptor-Interacting Protein Kinase 3 (RIPK3) inhibits autophagic flux during necroptosis in intestinal epithelial cells.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Colorectal and gastric metastases from lobular breast cancer that resembled superficial neoplastic lesions2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of Factors Affecting the Sensitivity of Bile Duct Brush Cytology2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] The usefulness of wire-guided endoscopic snare papillectomy for tumors of the major duodenal papilla2019

Author(s)

Journal Title

DOI

Data Source

kobayashi masanori 小林正典

Kobayashi Masanori 小林正典

[Presentation] 総胆管に穿破した主膵管型IPMNの1例2019