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KATO Yuzo  加藤 有三

ORCIDConnect your ORCID iD *help
Researcher Number 20014128
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 教授
2002 – 2005: 長崎大学, 大学院・医歯薬学総合研究科, 教授
1987 – 2001: 長崎大学, 歯学部, 教授
Review Section/Research Field
Principal Investigator
Functional basic dentistry / Functional basic dentistry
Except Principal Investigator
Functional basic dentistry / Functional basic dentistry / 病態科学系歯学(含放射線系歯学)
Keywords
Principal Investigator
osteoclast / Knockout mouse / signal transduction / cathepsin E / atopic disease / aspartic proteinase / Shedding / RANKL / Osteoprotegerin (OPG) / Osteoclast … More / Metalloprotease / Glycolipid / メタロプロテアーゼ / プロセッシング / ODF / 破骨細胞 / transport / Porphyromonas gingivalis / periodontal disease / Lys-gingipain / cysteine proteinase / Arg-gingipain / メダラシン / カテプシンH / カテプシンB / カテプシンE / カテプシンD / Cathepsin E / Cathepsin D / Cathepsin H / Cathepsin B / Lysosomal proteinases / 抗炎症剤 / リソゾーム酵素 / カテプシンL / リソゾーム性酵素 / knockout mice / atonic disease / knockout mouse / Processing Enzyme / _D-PDMP / ADAM / OPG / プロセッシング酵素 / ODF(RANKL) / Processing enzyme / D-PDMP / metalloprotease-disintegrins / osteoprotegerin (OPG) / osteoclast differentiation factor (ODF) / shedding / 遺伝子 / PCR. / 融合 / プロテアーゼ / メタロプロテアーゼ-ディスインテグリン / オステオプロテグリン(OPG) / 破骨細胞分化因子(ODF) / シェディング(shedding) / Ether anesthesia / Hypocalcemia / Ionized calcium / Osteocalcin / Rat / ストレス / 血漿中イオン化Ca / 血清中イオン化Ca / エーテル麻酔 / 低カルシウム血症 / イオン化カルシウム / オステオカルシン / ラット / periodontitis disease / periodonatal disease / Sec / ディフィレンシャル ディスプレー / mRNA / PCR / ディフィレッシャル ディスプレー / エナメル芽細胞 / プロテア-ゼ / 細胞内プロテア-ゼ / リソゾ-ム性酵素 … More
Except Principal Investigator
transport / Lys-gingipain / cysteine proteinase / Arg-gingipain / 破骨細胞 / periodontitis disease / GM1 / LPS / Porphysomonas gingivalis / periodontal disease / Porphyromonas gingivalis / LIPID RAFT / OSTEOCLAST / 脂質ラフト / TRAP / M-CSF / RANKL / Peophyromonas gingivalis / periodntitis disease / GLYCOSPHINGOLIPID / TLR4 / スフィンゴ糖脂質 / ANNEXIN / アネキシン / osteoclast / nitric oxide (NO) / fluorescence substrate / apoptosis / caspase / プロテアーゼ / MNA / 一酸化チッ素(NO) / 蛍光基質 / アポトーシス / カスパーゼ / proteasome / tunicamycin / cathepsin E / oligosaccharide side chain / quality control / protein / カテプシン / 小胞体 / 細胞内蛋白質輸送 / プロテアソーム / ツニカマイシン / カテプシンE / 糖鎖 / クオリティーコントロール / タンパク質 / Osteocalcin / Osteopontin / Bone Resorption Factor / Osteoblast / Osteoclast / Circadian rhythm / Bone Resorption / Alveolar Bone Resorption / 組織再生法 / 骨吸収促進物質 / 細胞内プロテア-ゼ / 病態モデル / 扁平上皮癌株細胞 / カテプシンD / bisphosphonate / 骨吸収病態モデル / 概口リズム / オステオカルシン / オステオポンチン / 局所的骨吸収因子 / 骨芽細胞 / 概日リズム / 骨吸収 / 歯槽骨吸収 / 抗菌作用 / ラクトフェリン / 唾液 / ノックアウトマウス / IL-1 / TNF受容体 / TNF / サイトカイン / 歯周病 Less
  • Research Projects

    (18 results)
  • Research Products

    (3 results)
  • Co-Researchers

    (25 People)
  •  Study of membrane transport system in proteinase produced from Porphyromonas gingivalis

    • Principal Investigator
      OKAMOTO Kuniaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  歯周病原性細菌におけるタンパク質の新規膜透過システムの解明Principal Investigator

    • Principal Investigator
      加藤 有三
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  FUNCTIONAL REGULATION OF OSTEOCLAST BY GLYCOSPHINGOLIPID

    • Principal Investigator
      SAKAI Eiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      NAGASAKI UNIVERSITY
  •  Study of the correlation bone in osteoclast resorption with atopic diseasePrincipal Investigator

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      NAGASAKI UNIVERSITY
  •  Establishment of protein expression system in Porphyromonasi gingivalis

    • Principal Investigator
      OKAMOTO Kuniaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      NAGASAKI UNIVERSITY
  •  歯周病原性細菌における新規の膜結合型タンパク質の遺伝学的探求とその精製の試みPrincipal Investigator

    • Principal Investigator
      加藤 有三
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  FUNCTION OF ANNEXIN FAMILY PROTEINS IN OSTEOCLAST DIFFERENTIATION AND ACTIVATION

    • Principal Investigator
      SAKAI Eiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  炎症性サイトカイン関連遺伝子変異マウスを用いて歯周組織破壊と再生の機序を解析する

    • Principal Investigator
      山口 朗
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Nagasaki University
  •  Design and application of new fluoroescent substrate against membrane-bound processing enzymePrincipal Investigator

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      NAGASAKI UNIVERSITY
  •  A novel method for fluorescence microscopic demonstration of caspase activity

    • Principal Investigator
      SAKAI Hideaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University School of Dentistry
  •  Roles of metalloprotease-disintegrins in osteoclastogenesisPrincipal Investigator

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University School of Dentistry
  •  エナメル芽細胞におけるRNAフィンガーブリンティングPrincipal Investigator

    • Principal Investigator
      加藤 有三
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Quality control mechanism for secretory proteins in intracellular protein sorting pathway

    • Principal Investigator
      SAKAI Hideaki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Role of osteocalcin in the calcium metabolism disorderPrincipal Investigator

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Studies of the Etiology and Therapeutic Approach of Alveolar Bone Resorption

    • Principal Investigator
      OGURA Hideaki
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  硬組織に由来する細胞の機能発現とリソゾ-ム性酵素の役割に関する実験薬理学的研究Principal Investigator

    • Principal Investigator
      加藤 有三
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  唾液内ラクトフェリンの抗菌機序と歯科疾患適用への基礎的研究

    • Principal Investigator
      山本 健二
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University
  •  Roles of lysosomal proteinases in the patho-physiological changes of hard tissues.Principal Investigator

    • Principal Investigator
      KATO Yuzo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Nagasaki University

All 2006 2005 2004

All Journal Article

  • [Journal Article] Pepstatin A, an aspartic proteinase inhibitor, suppresses RANKL-induced osteoclast differentiation.2006

    • Author(s)
      Yoshida H., Okamoto K., Iwamoto T., Sakai E., Kanaoka K., Hu JP., Shibata M., Hotokezaka H, Nishishita K., Mizuno A., Kato Y.
    • Journal Title

      J.Biochem. 139

      Pages: 583-590

    • NAID

      10018847122

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591942
  • [Journal Article] Taste cell responses in the frog are modulated by parasympathetic efferent nerve fibers.2005

    • Author(s)
      Sato T., Nishishita K., Kato Y., et al.
    • Journal Title

      Chem.Sences 30

      Pages: 761-769

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390563
  • [Journal Article] Laminin □2 Is Essential for Odontoblast Differentiation Regulation Dentin Siaroprotein Expression.2004

    • Author(s)
      Yuasa K, Fukumoto S, Kamasaki Y, Yamada A, Fukumoto E, Kanaoka K, Saito K, Harada H, Arikawa-Hirasawa E, Miyagoe-Suzuki Y, Takeda S, Okamoto K, Kato Y, Fujiwara T.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 10286-10292

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591971
  • 1.  SAKAI Eiko (10176612)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 1 results
  • 2.  OKAMOTO Kuniaki (10311846)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 2 results
  • 3.  SAKAI Hideaki (40225769)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  SHIBATA Mitsue (20274665)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  NISHISHITA Kazuhisa (20237697)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 6.  OZAKI Miho (50191341)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  YAMAMOTO Kenji (40091326)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  KOBAYASHI Yashuhiro (20264252)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NAKAYAMA Koji (80150473)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  AWAYA Akira
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OGURA Hideaki (20013831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  MUROTA Sei-itsu (50072989)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MATSUMOTO Akira (40064365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUDA Tatsuo (90014034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ENOMOTO Shoji (40013940)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATAKI Shiro (80157221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MATSUDA Naoki (00304973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  FUKUMOTO Satoshi (30264253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  朔 敬 (40145264)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山口 朗 (00142430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  柴田 恭明 (80253673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  藤田 修一 (00181355)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  原 宜興 (60159100)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  高橋 弘 (20124597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  高木 浩司 (40244074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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