MISAWA Miwa 三澤美和

Researcher Number	20061294
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004 – 2007: 星薬科大学, 薬学部, 教授 2005: Hoshi University, Department of Pharmacology, School of Pharmacy, 薬理学教室, 教授 2003: 星薬科大学, 薬理学教室, 教授 2002: Hoshi University, School of Pharmacy, Professor, 薬学部, 教授 2001: 星薬科大学, 薬理学教室, 教授 1995 – 1996: 星薬科大学, 薬学部, 教授 1991 – 1993: 星薬科大学, 教授
Review Section/Research Field	Principal Investigator General pharmacology / Biological pharmacy / General pharmacology
Keywords	Principal Investigator RhoA / 気管支喘息 / 気道過敏性 / bronchial asthma / CPI-17 / Ca^<2+>感受性 / Ca^<2+> sensitization / airway hyperresponsiveness / Rho kinase / 転写因子 … More / 気道過敏症 / ムスカリン受容体 / Gタンパク / Caチャネル / ニューロキニン / β受容体 / 気管支平滑筋 / sensory neuropeptide / ACh受容体 / neutral endopeptidase / Ca availability / muscarinic receptors / G protein / Ca^<2+> channel / neurokinins / beta-receptors / Rho A / 三量体Gタンパク質 / airway hvperesponsiveness / RhoA mRNA / CPI-17 mRNA / 膜translocation / 膜translacetion / endothelin / TNFα / rhoA mRNA / cpi-17 mRNA / membrane tranlocation / 気道渦敏性 / statin / ゲラニルゲラニル化 / lovastatin / glucocorticoid / Il-13 / STAT6 / airway hyperesponsiveness / transcription factor / statins / geranylgeranylation … More Except Principal Investigator 学術用語 / 薬学用語 / 標準化 / Scientific terms / Terms in pharmaceutical sciences / Standerdization Less

Identification of transcription factors of contractile element of bronchial smooth muscle and its change in activity at airway hyperresponsivenessPrincipal Investigator
- Principal Investigator
  
  MISAWA Miwa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Studies on change in airway hyperresponsiveness at bronchial asthma using the technique of RhoA gene manipulationPrincipal Investigator
- Principal Investigator
  
  MISAWA Miwa
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Change in RhoA activating mechanism in airway hyperresponsive bronchial smooth muscle.Principal Investigator
- Principal Investigator
  
  MISAWA Miwa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Hoshi University
Studies on mechanisms of development of airway hyperresponsiveness in rat bronchial asthmaPrincipal Investigator
- Principal Investigator
  
  MISAWA Miwa
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hoshi University
Investigation for the Standardization of Terms on Pharmaceutical Sciences
- Principal Investigator
  
  SUGA Tetsuya
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Institution
  Tokyo College of Pharmacy

All 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] メディカルバイオ2008
- Author(s)
  千葉義彦、三澤美和
- Publisher
  株式会社オーム社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Book] カッシング薬理学(原著9版)2005
- Author(s)
  三澤美和ら(監訳)
- Total Pages
  1270
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-15590236
[Book] カッツング薬理学(原著9版)(監訳)2005
- Author(s)
  三澤美和ら
- Total Pages
  1270
- Publisher
  丸善
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholne2008
- Author(s)
  Sakai, H., Yamamoto, M., Chiba, Y. and Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 44
  
  Pages: 9-16
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyper-responsiveness by inhibiting upregulation of RhoA in rats.2008
- Author(s)
  Chiba, Y., Goto. K., Hiraha-ra, M., Sakai, H., Misawa, M.
- Journal Title
  
  J. Pharmacol. Sci. 43
  
  Pages: 615-625
- NAID
  10024320036
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Lovastatin inhibits bronchial hyperresponsiveness by reducing RhoA signaling in rat allergic asthma.2008
- Author(s)
  Chiba, Y., Arima, J., Sakai, H., Misawa, M.
- Journal Title
  
  Am, J. Physiol. Lung Cell. Mol. Physiol. 294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Lovastatin inhibits bronchial hyperresponsiveness by reducingRhoA signaling in rat allergic asthma.2008
- Author(s)
  Chiba, Y., Arima, J., Sakai, H.and Misawa, M.
- Journal Title
  
  Am.J.Physiol.Lung Cell.Mol.Physiol 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucocorticoids inhibited airway hyperresponsiveness throughdownregUlation of CPI-17 in bronchial smooth muscle2008
- Author(s)
  Goto, K., Chiba, Y., Sakai, H.and Misawa, M.
- Journal Title
  
  Eur.J.Pharmacol (In print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucoconicoids ameliorate anbigen-induced bronchial smooth musde hyperresponsiveness by inhibiting upregulation or RhoA in rats2008
- Author(s)
  Chiba, Y., Goto. K., Hhrahara, M., Sakai, H.and Misawa, M.
- Journal Title
  
  J.Pharmacol.Sci 43
  
  Pages: 615-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucocorticoids inhibited airway hyperresponsiveness through downregulation of CPI-17 in bronchial smooth muscle2008
- Author(s)
  Goto, K., Chiba, Y., Sakai, H. and Misawa, M.
- Journal Title
  
  Eur.J.Pharmacol (In print)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] RhoA-kinase(ROcK)inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contaction2008
- Author(s)
  Hanazaki, M., Yokoyama, M., Morita, K., Kohjitani, A., Sakai, H., Chiba, Y and Misawa, M.
- Journal Title
  
  Anesthesia & Analgesia (In print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Bronchial Asthma and Bronchial Smooth Muscle Hyperresponsiveness.2008
- Author(s)
  Chiba, Y., Misawa, M.
- Journal Title
  
  Medical Bio(Ohmsa) 5(2)
  
  Pages: 44-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Probable involvement of epsilon-isoform of protein kinase C inrat bronchial smooth musde contraction induced by acetylchone2008
- Author(s)
  Sakai, H., Yamamoto, M., Chiba, Y.and Misawa, M.
- Journal Title
  
  J.Smooth Musde Res 44
  
  Pages: 9-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Lovastatin inhibits bronchial hyperresponsiveness by reducing RhoA signaling in rat allergic asthma2008
- Author(s)
  Chiba, Y., Arima, J., Sakai, H. and Misawa, M.
- Journal Title
  
  Am.J.Physiol.Lung Cell.Mol.Physiol 294
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyperresponsiveness by inhibiting upregulation or RhoA in rats2008
- Author(s)
  Chiba, Y., Goto.K., Hiraha-ra, M., Sakai, H. and Misawa, M.
- Journal Title
  
  J.Pharmacol.Sci. 43
  
  Pages: 615-625
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] RhoA-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contaction2008
- Author(s)
  Hanazaki, M., Yokoyama, M., Morita, K., Kohjitani, A., Sakai, H., Chiba, Y. and Misawa, M.
- Journal Title
  
  Anesthesia & Analgesia 106
  
  Pages: 1765-1771
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Glucocorticoids inhibited airway hyperresponsiveness through downregulation of CPI-17 in bronchial smooth muscle.2008
- Author(s)
  Goto, K., Chiba, Y., Sakai, H., Misawa, M.
- Journal Title
  
  Eur. J. Pharmacol (In print)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholne.2008
- Author(s)
  Sakai, H., Yamamoto, M., Chiba, Y., Misawa, M.
- Journal Title
  
  J. Smooth Muscle Res. 44
  
  Pages: 9-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] RhoA-kinase inhibitors augment the inhibitoryeffect of propofol on rat bronchial smooth muscle contaction.2008
- Author(s)
  Hanazaki, M., Yokoyama, M., Morita, K., Kohjitani, A., Sakai, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Anesthesia & Analgesia 106
  
  Pages: 1765-1771
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Increase in the expression of matrix metalloproteinase-12 in the airways of ratswith allergic bronchial asthma2007
- Author(s)
  Chiba, Y., Yu, Y., Sakai, H.and Misawa, M.
- Journal Title
  
  Biol.Pharm.Bull 30
  
  Pages: 318-323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Involvements of cysteinyl leukotrienes and nitric oxide in antigen-induced venodilatation of nasal mucosa in sensitized rats in vivo2007
- Author(s)
  Chiba, Y., Oshita, M., Sakai, H. and Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 43
  
  Pages: 139-144
- NAID
  110006404994
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Increase in the expression of matrix metalloproteinase-12 in the airways of rats with allergic bronchial asthma.2007
- Author(s)
  Chiba, Y., Yu, Y., Sakai, H., Misawa, M.
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 318-323
- NAID
  110006162851
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Increase in the expression of matrix metalloproteinase-12 in the airways of rats with allergic bronchial asthma2007
- Author(s)
  Chiba, Y., Yu, Y., Sakai, H., Misawa, M.
- Journal Title
  
  Biol. Pharm. Bull. 30
  
  Pages: 318-323
- NAID
  110006162851
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Involvements of cystei-nyl leukotrienes and nitric oxide in antigen-induced venodilatation of nasal mucosa in sensitized ratsin vivo.2007
- Author(s)
  Chiba, Y., Oshita, M., Sakai, H., Misawa, M.
- Journal Title
  
  J. Smooth Muscle Res. 43
  
  Pages: 139-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Increase in the expression of matrix metalloproteinase-12 in the airways of rats with allergic bronchial asthma2007
- Author(s)
  Chiba, Y., Yu, Y., Sakai, H., and Misawa, M.
- Journal Title
  
  Biol.Pharm.Bull. 30
  
  Pages: 318-323
- NAID
  110006162851
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Involvements of cysteinyl leukotrienes and nitric oxide in antigen-induced venodilatation of nasal mucosa in sensitized rats in vivo2007
- Author(s)
  Chiba, Y., Oshita, M., Sakai, H.and Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res 43
  
  Pages: 139-144
- NAID
  110006404994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Uteroglobin-related protein 1 expression suppesses allergic airway inflammation in mice2006
- Author(s)
  Chiba, Y., Kurotani.R., Kusakabe, T., Miura, T., Link, B.W., Misawa, M., Kimura, S.
- Journal Title
  
  Am. J. Respir. Crit. Care Med. 173
  
  Pages: 958-964
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Uteroglobin-related protein 1 expression suppesses allergic airway inflammation in mice2006
- Author(s)
  Chiba, Y., Kurotani, R., Kusakabe, T., Miura, T., Link, B.W., Misawa, M., Kimura, S.
- Journal Title
  
  Am.J.Respir.Crit.Care Med. 173
  
  Pages: 958-964
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Comparison of norepinephrine responsiveness of mucosal veins in vivo with that of isolated mucosal tissue in vitro in guinea pig nasal mucosa2006
- Author(s)
  Chiba, Y., Oshita, M., Matsuo, K., Sakai, H., Misawa, M.
- Journal Title
  
  Am. J. Rhinol. 20
  
  Pages: 349-352
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Effects of 1400W, a potent selective inducible NOS inhibitor, on histamine- and leukotriene D_4-induced relaxation of isolated guinea pig nasal mucosa2006
- Author(s)
  Chiba, Y., Matsuo, K., Sakai, H., Abe, K., Misawa, M.
- Journal Title
  
  Nitric Oxide 15
  
  Pages: 142-147
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Augmentation of endothelin-1-induced phosphoryation of CPI-17 and myosin light chain in bronchial smooth muscle from airway hyperresponsive rats2006
- Author(s)
  Sakai, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages: 1897-1899
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice2006
- Author(s)
  Chiba, Y., Kurotani, R., Kusakabe, T., Miura, T., Link, B.W., Misawa, M
- Journal Title
  
  Am. J. Respir. Crit. Care Med. 173
  
  Pages: 958-964
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Increased expression of inducible nitric oxide synthase in nasal mucosae of guinea pigs with induced allergic rhinitis2006
- Author(s)
  Chiba, Y., Matsuo, K., Sakai, H., Misawa, M.
- Journal Title
  
  Am. J. Rhinol. 20
  
  Pages: 336-341
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Impaired norepinephrine-mediated contraction of isolated nasal mucosa in guinea pigs with allergic rhinitis2006
- Author(s)
  Chiba, Y., Matsuo, K., Sakai, H., Misawa, M.
- Journal Title
  
  Am. J. Rhinol. 20
  
  Pages: 477-479
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Regional differences in vascular responsiveness of nasal mucosae isolated from naive guinea pigs2006
- Author(s)
  Chiba, Y., Matsuo, K., Sakai, H., Abe, K., Misawa, M.
- Journal Title
  
  Auris Nasus Larynx (Epub)
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Role of Rho kinase in endothelin-1-induced phosphorylation of CPI-17 in rat bronchial smooth muscle2006
- Author(s)
  Sakai, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Pulm. Pharmacol. Ther. (Epub)
- Data Source
  KAKENHI-PROJECT-18590246
[Journal Article] Effect of cigarette smoke exposure in vivo on bronchial smooth muscle contractility in vitro in rats2005
- Author(s)
  Chiba, Y., Murata, M., Ushikubo, H., Yoshikawa, Y., Saitoh, A., Sakai, H., Kamei, J., Misawa, M.
- Journal Title
  
  Am.J.Respir.Cell.Mol.Biol. 33
  
  Pages: 574-581
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation and membrane translocation of CPI-17 in bronchial smooth muscle of rats2005
- Author(s)
  Sakai, H., Hirano, T., Chiba, Y., Misawa, M.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol. 289
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of M_3 muscarinic receptors in ACh-induced increase in membrane-associated RhoA of rat bronchial smooth muscle2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 625-628
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Difference in the effects of cigarette smoke exposure on bronchial smooth muscle contractility in rats2005
- Author(s)
  Chbia, Y., Murata, M., Yoshikawa, Y., Saitoh, A., Sakai, H., Kamei, J., Misawa, M.
- Journal Title
  
  Med.Hypothesis Res. 2
  
  Pages: 597-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of M_3 muscarinic receptors in Ach-induced increase in membrane-associated RhoA of rat bronchial smooth muscle2005
- Author(s)
  Sakai, H., Shirai, T., Yamamoto, M., Chiba, Y., Misawa, M.
- Journal Title
  
  Biol.Pharm.Bull. 28(accepted)
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats2005
- Author(s)
  Sakai, H., Misawa, M.
- Journal Title
  
  Basic Clin.Pharmacol.Toxicol. 96
  
  Pages: 54-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of RhoA-mediated Ca^<2+> sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice2005
- Author(s)
  Chiba, Y., Ueno, A., Shinozaki, K., Takayama, H., Sakai, H., Misawa, M.
- Journal Title
  
  Respir.Res. 6(accepted)
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of RhoA-mediated Ca^<2+> sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice2005
- Author(s)
  Chiba, Y., Ueno, A., Shinozaki, K., Takeyama, H., Sakai, H., Misawa, M.
- Journal Title
  
  Respir.Res. 6(#4)
  
  Pages: 1-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats2005
- Author(s)
  Sakai, H., Misawa, M.
- Journal Title
  
  Basic Clin.Pharmacol.Toxical. 96
  
  Pages: 54-59
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle : roles of Rho kinase and protein kinase C2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Can.J.Physiol.Pharmacol. (accepted)
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effects of repeated antigen exposure on endothelin-1-induced bronchial smooth muscle contraction and activation of RhoA in sensitized rats2005
- Author(s)
  Chiba, Y., Sakai, H., Yu, Y-Y, Misawa, M.
- Journal Title
  
  J. Biochem. (Tokyo) 137
  
  Pages: 751-756
- NAID
  10017345755
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of RhoA-mediated Ca^<2+> sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice2005
- Author(s)
  Chiba, Y., Ueno, A., Shinozaki, K., Takeyama, H., Sakai, H., Misawa, M.
- Journal Title
  
  Respir. Res. 6(#4)
  
  Pages: 1-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of RhoA-mediated Ca^<2+> sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice2005
- Author(s)
  Chiba, Y., Ueno, A., Shinozaki, K., Takeyama, H., Sakai, H., Misawa M.
- Journal Title
  
  Respir.Res. 6(4)
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of M_3 muscarinic receptors in ACh-induced increase in membrane-associated RhoA of rat bronchial smooth muscle2005
- Author(s)
  Sakai, H., Shirai, T., Yamamoto, M., Chiba, Y., Misawa, M.
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 625-628
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Possible involvement of CPI-17 in augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsive rats2005
- Author(s)
  Sakai, H., Hirano, T., Chiba, Y., Takeyama, H., Misawa, M.
- Journal Title
  
  Mol.Pharmacol. 68
  
  Pages: 145-151
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Endothelin-1-induced translocation of RhoA is mediated by endothelin ET_A receptors in rat bronchial smooth muscle2005
- Author(s)
  Chiba, Y., Sakai, H., Misawa, M.
- Journal Title
  
  Eur.J.Pharmacol. 517
  
  Pages: 182-185
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation and membrane translocation of CPI-17 in bronchial smooth muscle of rats2005
- Author(s)
  Sakai, H., Hirano, T., Chiba, Y., Misawa, M.
- Journal Title
  
  Am.J.Physiol.Lung Cell.Mol.Physiol. 289
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effects of repeated antigen exposure on endothelin-1-induced bronchial smooth muscle contraction and activation of RhoA in sensitized rats2005
- Author(s)
  Chiba, Y., Sakai, H., Yu, Y-Y., Misawa, M.
- Journal Title
  
  J.Biochem.(Tokyo) 137
  
  Pages: 751-756
- NAID
  10017345755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Endothelin-1-induced translocation of RhoA is mediated by endothelin ET_A receptors in rat bronchial smooth muscle2005
- Author(s)
  Chiba, Y., Sakai, H., Misawa, M.
- Journal Title
  
  Eur. J. Pharmacol. 517
  
  Pages: 182-185
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle : roles of rho-kinase and protein kinase C2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Can. J. Physiol. Pharmacol. 83
  
  Pages: 375-381
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle : roles of Rho-kinase and protein kinase C2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Can.J.Physiol.Pharmacol. 83
  
  Pages: 375-381
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Difference in the effects of cigarette smoke exposure on bronchial smooth muscle contractility in rats2005
- Author(s)
  Chiba, Y., Murata, M., Yoshikawa, Y., Saitoh, A., Sakai, H., Kamei J., Misawa M.
- Journal Title
  
  Med.Hypothesis Res. 2
  
  Pages: 597-603
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Possible involvement of CPI-17 in augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsiveness rats2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Mol.Pharmacol. 68
  
  Pages: 145-151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Difference in the effects of cigarette smoke exposure on bronchial smooth muscle contractility in rats2005
- Author(s)
  Chiba, Y., Murata, M., Yoshikawa, Y., Saitoh, A., Sakai, H., Kamei, J., Misawa, M.
- Journal Title
  
  Med. Hypothesis Res. 2
  
  Pages: 597-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Possible involvement of CPI-17 in augmented bronchial smooth muscle contraction in antigen-induced airway hyperresponsiveness rats2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Mol. Pharmacol. 68
  
  Pages: 145-151
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats2005
- Author(s)
  Sakai, H., Misawa, M.
- Journal Title
  
  Basic Clin. Pharmacol. Toxicol. 96
  
  Pages: 54-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of sodium azulene sulfonate on capsaicin-induced pharyngitis in rats2005
- Author(s)
  Sakai, Misawa, M.
- Journal Title
  
  Basic Clin.Pharmacol.Toxicol. 96
  
  Pages: 54-59
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of M_3 muscarinic receptors in ACh-induced increase in membrane-associated RhoA of rat bronchial smooth muscle2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 625-628
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of cigarette smoke exposure in vivo on bronchial smooth muscle contractility in vitro in rats2005
- Author(s)
  Chiba, Y., Murata, M., Ushikubo, H., Saitoh, A., Sakai, H., Kamei, J., Misawa, M.
- Journal Title
  
  Am.J.Respir.Cell.Mol.Biol. 33
  
  Pages: 574-581
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effects of repeated antigen exposure on endothelin-1-induced bronchial Smooth muscle contraction and activation of RhoA in sensitized rats.2005
- Author(s)
  Chiba, Y., Sakai, H., Yu, Y., Misawa, M.
- Journal Title
  
  J.Biochem.(Tokyo) 137
  
  Pages: 751-756
- NAID
  10017345755
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Effect of cigarette smoke exposure in vivo on bronchial smooth muscle contractility in vitro in rats2005
- Author(s)
  Chiba, Y., Murata, M., Ushikubo, H., Saitoh, A., Sakai, H., Kamei, J., Misawa, M.
- Journal Title
  
  Am. J. Respir. Cell. Mol. Biol. 33
  
  Pages: 574-581
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle : the roles of Rho-kinase and protein kinase C2005
- Author(s)
  Sakai, H., Hirano, T., Takeyama, H., Chiba, Y., Misawa, M.
- Journal Title
  
  Can.J.Physiol.Pharmacol. 83
  
  Pages: 375-381
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] TNF-α augment the expression of RhoA in rat bronchus2004
- Author(s)
  Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 40
  
  Pages: 25-34
- NAID
  110002912889
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] TNF-α augments the expression of RhoA in rat bronchus2004
- Author(s)
  Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J. Smooth Muscle Res. 40
  
  Pages: 25-34
- NAID
  110002912889
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] TNF-α augments the expression of RhoA in rat bronchus2004
- Author(s)
  Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 40
  
  Pages: 25-34
- NAID
  110002912889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of p42/44 MAPK and RhoA protein in augmentation of ACh-induced bronchial smooth muscle contraction by TNF-α2004
- Author(s)
  Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J.Appl.Physiol. 97
  
  Pages: 2154-2159
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Hyperresponsiveness of bronchial but not tracheal smooth muscle in a murine model of allergic bronchial asthma2004
- Author(s)
  Chiba, Y., Ueno, A., Sakai, H., Misawa, M.
- Journal Title
  
  Inflamm.Res. 53
  
  Pages: 636-642
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] The role of RhoA-mediated Ca^<2+>- sensitization of bronchial smooth muscle contraction in airway hyperresponsiveness2004
- Author(s)
  Chiba, Y., Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 40
  
  Pages: 155-167
- NAID
  110002952048
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] The role of RhoA-mediated Ca^2+ sensitization of bronchial smooth muscle contraction in airway hyperresponsiveness2004
- Author(s)
  Chiba, Y., Misawa, M.
- Journal Title
  
  J. Smooth Muscle Res. 40
  
  Pages: 155-167
- NAID
  110002952048
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of p42/44 MARK and RhoA protein in the augmentation of ACh-induced bronchial smnooth muscle contraction by TNF-α in rats2004
- Author(s)
  Sakai, H., Otogotom, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J.Appl.Physiol. 97
  
  Pages: 2154-2159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced translocation of RhoA in freshly isolated single smooth muscle cells of rat bronchi2004
- Author(s)
  Chiba, Y., Uchida, T., Sakai, H., Oku, T., Ito, S., Tsuji, T., Misawa, M.
- Journal Title
  
  J. Pharmacol. Sci. 95
  
  Pages: 479-482
- NAID
  10014165998
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced translocation of RhoA in freshly isolated single smooth muscle cells of rat bronchi2004
- Author(s)
  Chiba, Y., Uchida, T., Sakai, H., Oku, T., Itoh, S., Tsuji, T., Misawa, M.
- Journal Title
  
  J.Pharmacol.Sci. 95
  
  Pages: 479-482
- NAID
  10014165998
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Hyperresponsiveness of bronchial but not tracheal smooth muscle in a murine model of allergic bronchial asthma2004
- Author(s)
  Chiba, Y., Ueno, A., Sakai, H., Misawa, M.
- Journal Title
  
  Inflamm. Res. 53
  
  Pages: 636-642
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] The role of RhoA-mediate Ca^<2+> sensitization of bronchial smooth muscle contraction in airway hyperresponsiveness2004
- Author(s)
  Chiba, Y., Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 40
  
  Pages: 155-167
- NAID
  110002952048
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Acetylcholine-induced translocation of RhoA in freshly isolated single smooth muscle cells of rat bronchi2004
- Author(s)
  Chiba, Y., Uchida, T., Sakai, H., Oku, T., Ito, S., Tsuji, T., Misawa, M.
- Journal Title
  
  J.Pharmacol.Sci. 95
  
  Pages: 479-482
- NAID
  10014165998
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of L-type Ca^<2+> channels in the induction of long-term potentiation in the basolateral amygdala-dendate gyrus pathway of anesthetized rats2004
- Author(s)
  Niikura, Y., Abe, K., Misawa, M.
- Journal Title
  
  Brain Res. 1017
  
  Pages: 218-221
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Hyperresponsiveness of bronchial but not tracheal smooth muscle in a murine model of allergic bronchial asthma2004
- Author(s)
  Chiba, Y., Ueno, A., Sakai, H., Misawa, M.
- Journal Title
  
  Inflam.Res. 53
  
  Pages: 636-642
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Involvement of p42/44 MAPK and RhoA protein in the augmentation of ACh-induced bronchial smooth muscle contraction by TNF-α in rats2004
- Author(s)
  Sakai, H., Otogoto, S., Chiba, Y., Abe, K., Misawa, M.
- Journal Title
  
  J. Appl. Physiol. 97
  
  Pages: 2154-2159
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] GABA_A receptor-mediated inhibition by ethanol of long-term potentiation in the basolateral amygdala-dendate gyrus pathway in vivo2004
- Author(s)
  Abe, K., Niikura, Y., Misawa M.
- Journal Title
  
  Neuroscience 125
  
  Pages: 113-117
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Astrocyte stellation induced by Rho kinase inhibitors in culture2003
- Author(s)
  Abe, K., Misawa, M.
- Journal Title
  
  Brain Res.Dev.Brain Res. 143
  
  Pages: 99-104
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Upregulation of rhoA mRNA in bronchial smooth muscle of antigen-induced airway hyperresponsive rats2003
- Author(s)
  Chiba, Y., Sakai, H., Wachi, H., Sugitani, H., Sayama, Y., Misawa, M.
- Journal Title
  
  J.Smooth Muscle Res. 39
  
  Pages: 221-228
- NAID
  110002912882
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Journal Article] Upregulation of rhoA mRNA in bronchial smooth muscle of antigen-induced airway hyperresponsive rats2003
- Author(s)
  Chiba, Y., Sakai, H., Wachi, H., Sugitani, H., Seyama, Y., Misawa, M.
- Journal Title
  
  J. Smooth Muscle Res. 39
  
  Pages: 221-228
- NAID
  110002912882
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590236
[Presentation] Pharmacologial studies on the respiratory tract(Rept.305):Development of cigarette smoke-induced bronchial muscle hyperresponsiveness in rats depends on tar and nicotine contents2008
- Author(s)
  Fujita, A., Ushikubo, H., Chiba, Y., Sakai, H., Kamei, J. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Effects of cigarette smoke exposure on airway responsiveness in C57BL/6J mice.2008
- Author(s)
  Matsuuchi, N., Ushikubo, H., Fujita, A., Sakai, H., Chiba, Y., Kamei, J., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.305):Development of cigarette smoke-induced bronchial muscle hyperresponsiveness in rats depends on tar and nicotine contents2008
- Author(s)
  Fujita, A., Ushikubo, H., Chiba, Y., Sakai, H., Kamei, J. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on pressure ulcer (Rept.8):A new animal model of severe pressure ulcer using Wistar rats2008
- Author(s)
  Kusano, R., Ushikubo, H., Sakai, H., Chiba, Y.& Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.307):The role of sphingosine-1-phosphate(SIP) in airway hyperresponsiveness observed in murine allergic bronchial asthma2008
- Author(s)
  Takeuchi, H., Chiba, Y., Sakai, H. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.310):Increased expression of a disintegrin and metalloproteinase 8 in mice with allergic bronchial asthma2008
- Author(s)
  Onoda, S., Chiba, Y., Sakai, H., Hattori, Y., Maitani, Y., Kimura, S. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道平滑筋におけるカルシウム感受性調節機構と麻酔薬2008
- Author(s)
  花崎元彦、横山正尚、森田潔、糀谷淳、千葉義彦、三澤美和
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.309):Effect of a specific matrix metalloproteinase-12inhibitor on the pathogenesis of allergic bronchial asthma2008
- Author(s)
  Yu, Y., Chiba, Y., Sakai, H, & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.306):Effect of inhibitors of RhoA geranylgeranylation on antigen-induced airway hyperresponsiveness in mice2008
- Author(s)
  Sato S., Chiha, Y., Sakai, H. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第313報):アレルギー性気管支喘息モデルマウスの気道過敏性および気道炎症発現に及ぼすlovastatinの効果2008
- Author(s)
  佐藤駿介、千葉義彦、三澤美和
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.308):Augmented sodium nitroprusside-induced venodilatation of nasal mucosa in vivo in rats with allergic rhinitis2008
- Author(s)
  Uto, F., Enzaka, J., Oshita, M., Sakai, H., Chiba, Y.& Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Increased expression of a sisintegrin and metalloproteinase 8 in mice with allergic vronchial asthma.2008
- Author(s)
  Onoda, S., Chiba, Y., Sakai, H., Hattori, Y., Maitani, Y., Kimura, S., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.302):RACKl as a binding partner for CPI-17 in bronchial smooth muscle2008
- Author(s)
  Tanabe, M., Chiba, Y., Kimura, S. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.303):Involvement of actin polymerization in antigen-induced airway hyperresponsiveness in rats2008
- Author(s)
  Kozutsumi, Y., Chiba, Y., Salmi, H., & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第312報):培養ヒト気管支平滑筋細胞における各種SOCS分子種の発現に対するIL-13の効果2008
- Author(s)
  西田雄一、千葉義彦、轟倫子、三澤美和
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] RACK1as a binding partner for CPI-17 in bronchial smooth muscle.2008
- Author(s)
  Tanabe, M., Chiba, Y., Kimura, S., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第314報):培養ヒト気管支平滑筋細胞でのRhoAタンパ質発現におけるTNFα/NFkB経路およびIL-13/STAT6経路の関与2008
- Author(s)
  後藤久充子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] ラット褥瘡部皮膚組織におけるL-arginine代謝酵素の発現変化2008
- Author(s)
  木村有希、古川晃次、牛久保裕子、酒井寛泰医、千葉義彦、三澤美和
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on pressure ulcer(Rept.8):A new animal model of severe pressure ulcer using Wistar rats2008
- Author(s)
  Kusano, R., Ushikubo, H., Sakai, H., Chiba, Y. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.309):Effect of a specific matrix metalloproteinase-12 inhibitor on the pathogenesis of allergic bronchial asthma2008
- Author(s)
  Yu, Y., Chiba, Y., Sakai, H., & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Effect of inhibitors of RhoA geranylgeranylation on antigen-induced airway hyperresponsiveness in mice.2008
- Author(s)
  Sato S., Chiba, Y., Sakai, H., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 重症度の異なる二種類のラット褥瘡モデルの開発とその応用[シンポジウム]2008
- Author(s)
  牛久保裕子、千葉義彦、三澤美和
- Organizer
  第118回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] ラット褥瘡部皮膚組織における L-arghinine 代謝酵素の発現変化2008
- Author(s)
  木村有希、古川晃次、牛久保裕子、酒井寛泰医、千葉義彦、三澤美和
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.306):Effect of inhibitors of RhoA geranylgeranylation on antigen-induced airway hyperresponsiveness in mice2008
- Author(s)
  Sato S., Chiba, Y., Sakai, H.& Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.302):RACK1 as a binding partner for CPI-17 in bronchial smooth muscle2008
- Author(s)
  Tanabe, M., Chiba, Y., Kimura, S. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Change in the expression of matrix metalloproteinase-12 in airways of rats with allergic bronchial asthma2008
- Author(s)
  Todoroki, M., Chiba, Y., Sakai, H. and Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] The role of sphingosine-1-phosphate(S1P) in airway hyperresponsiveness observed in murine allergic bronchial asthma.2008
- Author(s)
  Takeuchi, H., Chiba, Y., Sakai, H., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第311報):培養ヒト気管支平滑筋細胞におけるTNFα/NFkB誘発RhoA upregulationに対するprednisoloneの効果2008
- Author(s)
  後藤久充子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Augmented sodium nitroprusside-venodilatation of nasal mucosa in vivo in rats with allergic rhinitis.2008
- Author(s)
  Uto, F., Enzaka, J., Oshita, M., Sakai, H., Chiba, Y., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第311報):培養ヒト気管支平滑筋細胞におけるTNFα/NFκ誘発RhoA upregulationに対するprednisoloneの効果2008
- Author(s)
  後藤久充子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Effect of a specific matrix metalloproteinase-12 inhibitor on the pathogenesis of allergic bronchial asthma.2008
- Author(s)
  Yu, Y., Chiba, Y., Sakai, H., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Change in the expression of matrix metalloproteinase-12 in airways of rats with allergic bronchiall asthma2008
- Author(s)
  Todoroki, M., Chiba, Y., Sakai, H.and Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.304):Effects of cigarette smoke exposure on airway responsiveness in C57BL/6Jmice2008
- Author(s)
  Matsuuchi, N., Ushikubo, H., Fujita, A., Sakai, H., Chiba, Y., Kamei, J.& Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Development of cigarette smoke-induced bronchial muscle hyperresponsiveness in rats depends on tar and nicotine contents.2008
- Author(s)
  Fujita, A., Ushikubo, H., Chiba, Y., Sakai, H., Kamei, J., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.304):Effects of cigarette smoke exposure on airway responslveness in C57BL/6J mice2008
- Author(s)
  Matsuuchi, N., Ushikubo, H., Fujita, A., Sakai, H., Chiba, Y., Kamei, J. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.310):Increased expression of a disintegrin and metalloproteinase 8 in mice with allergic bronchial asthma2008
- Author(s)
  Onoda, S., Chiba, Y., Sakai, H., Hattori, Y., Maitani, Y., Kimura, S. & Misawa, M
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract(Rept.303):Involvement of actin polymerization in antigen-induced airway hyperresponsiveness in rats.2008
- Author(s)
  Kozutsumi, Y. Chiba, Y., Sakai, H., & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Involvement of actin polymerization in antigen-induced airway hyperresponsiveness in rats.2008
- Author(s)
  Kozutsumi, Y., Chiba, Y., Sakai, H., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Change in the expression of matrix metalloproteinase-12 in airways of rats with allergic bronchial asthma.2008
- Author(s)
  Todoroki, M., Chiba, Y., Sakai, H., Misawa, M.
- Organizer
  In The 81st Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Phamacological studies on the respiratory tract(Rept.308):Augmented sodium nitroprusside-induced venodilatation of nasal mucosa in vivo in rats with allergic rhinitis2008
- Author(s)
  Uto, F., Enzaka, J., Oshita, M., Sakai, H., Chiba, Y. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] Pharmacological studies on the respiratory tract (Rept.307):The role of sphingosine-1-phosphate (S1P) in airway hyperresponsiveness observed in murine allergic bronchial asthma2008
- Author(s)
  Takeuchi, H., Chiba, Y., Sakai, H. & Misawa, M.
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第294報):IL-4およびIL-13により培養ヒト気管支平滑筋細胞で活性化されるSTATsの検討2007
- Author(s)
  轟倫子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第116回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第293報):Prednisoloneによる抗原誘発気道過敏性抑制機序におけるIL-13/STAT6経路の関与2007
- Author(s)
  後藤久充子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第116回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第300報):培養ヒト気管支平滑筋細胞のRhoAタンパク質発現におけるTNF-α/NF-κB系の関与2007
- Author(s)
  後藤久充子、千葉義彦、三澤美和
- Organizer
  第117回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第295報):培養ヒト気管支平滑筋におけるIL-4およびIL-13により活性化されるSTATsの同定2007
- Author(s)
  轟倫子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第9回応用薬理シンポジウム
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第297報):アレルギー性気管支喘息マウスの肺組織におけるADAM8発現の変化2007
- Author(s)
  小野田智、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第51回日本薬学会関東支部大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] TNF-α誘発RhoA pregulationにおけるNF-κBの関与2007
- Author(s)
  後藤久充子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] TNF-α 誘発 RhoA pregulation における NF-kBの関与2007
- Author(s)
  後藤久充子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第291報):ステロイドによる気道過敏性抑制はSTAT6活性化阻害を介する2007
- Author(s)
  後藤久充子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第298報):3系統マウスにおけるタバコ主流煙誘発気道過敏性の発症とRhoAの変動2007
- Author(s)
  松内則秀、牛久保裕子、藤田亜希子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第51回日本薬学会関東支部大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 褥瘡の薬理学的研究(第6報):ラット褥瘡部組織におけるMMP-9/TIMP-1バランスの変化2007
- Author(s)
  牛久保裕子、木崎早矢香、酒井寛泰、千葉義彦、三澤美和
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第299報):アレルギー性気管支喘息モデルマウスの肺組織において抗原チャレンジにより活性化されるSTATsの同定2007
- Author(s)
  轟倫子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第117回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 褥瘡の薬理学的研究(第7報):ラット褥瘡モデルの褥瘡発症・治癒過程における肥満細胞の関与2007
- Author(s)
  古川晃次、小林安里奈、牛久保裕子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第9回日本褥瘡学会学術大会
- Place of Presentation
  前橋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第297報):アレルギー性気管支喘息マウスの肺組織におけるN)AM8発現の変化2007
- Author(s)
  小野田智、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第51回日本薬学会関東支部大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第292報):マウスアレルギー性気管支喘息時の肺組織におけるinterleukin-13受容体(ILー13Ralpha1)mRNA発現の増加2007
- Author(s)
  千葉義彦、小野田智、轟倫子、中沢修司、酒井寛泰、服部喜之、米谷芳枝、三澤美和
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第295報):培養ヒト気管支平滑筋におけるIL-4およびIL-13により活性化されるSTATsの同定.2007
- Author(s)
  轟倫子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第9回応用薬理シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第296報):アレルギー性気管支喘息マウスの肺組織におけるmatrix metalloproteinase-12発現の変化2007
- Author(s)
  余穎妍、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第51回日本薬学会関東支部大会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第300報):培養ヒト気管支平滑筋細胞のRhoAタンパク質発現におけるTNF-α/NF-kB系の関与2007
- Author(s)
  後藤久充子、千葉義彦、三澤美和
- Organizer
  第117回日本薬理学会関東部会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第285報):Lovastain 前処置による RhoA 活性化と気道過敏性の抑制2006
- Author(s)
  有馬順子、千葉義彦、酒井寛泰、三澤美和
- Organizer
  第8回応用薬理シンポジウム
- Place of Presentation
  千葉市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第290報):抗原誘発鼻粘膜過敏性時のNO誘発鼻粘膜静脈弛緩反応の亢進とK^+channelの関与2006
- Author(s)
  遠坂純、大下未知子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第115回日本薬理学会関東部会
- Place of Presentation
  高崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第286報):抗原誘発鼻粘膜過敏性時の鼻粘膜における血管拡張反応とNO産生の変化2006
- Author(s)
  遠坂純、大下未知子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第8回応用薬理シンポジウム
- Place of Presentation
  千葉市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第288報):タバコ主流煙吸入暴露ラットではin vivo及びin vitroで気道過敏性が発症する2006
- Author(s)
  小松魅侑爾、牛久保裕子、村田真彦、松内則秀、亀井淳三、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第115回日本薬理学会関東部会
- Place of Presentation
  高崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 褥瘡の薬理学的研究(第5報):新規褥瘡モデルの褥瘡部皮膚組織中MMP-9の動態とその関連物質の変化2006
- Author(s)
  木崎早矢香、牛久保裕子、小林安里奈、三澤美和
- Organizer
  第8回日本褥瘡学会学術集会
- Place of Presentation
  さいたま市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第284報):抗原誘発気道過敏性発現に対するglucocorticoidsの効果2006
- Author(s)
  後藤久充子、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第8回応用薬理シンポジウム
- Place of Presentation
  千葉市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第287報):タバコ主流煙吸入暴露によるラットでの気道過敏性の証明2006
- Author(s)
  小松魅侑爾、牛久保裕子、村田真彦、松内則秀、亀井淳三、酒井寛泰、千葉義彦、三澤美和
- Organizer
  第8回応用薬理シンポジウム
- Place of Presentation
  千葉市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246
[Presentation] 気道の薬理学的研究(第289報):Acetylcholine誘発気管支平滑筋収縮におけるアクチン重合反応の関与2006
- Author(s)
  酒井寛泰、小堤友理、千葉義彦、三澤美和
- Organizer
  第115回日本薬理学会関東部会
- Place of Presentation
  高崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590246

1. CHIBA Yoshihiko (00287848)

# of Collaborated Projects: 3 results

# of Collaborated Products: 142 results
2. SUGA Tetsuya (20057318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. RIKIHISA Tadaaki (70012622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YAMANOUCHI Sakae (20059249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YOSHIDA Takemi (20138415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAGAI Tuneji (40061270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOMIOKA Kiyoshi (50114575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAMEJIMA Keijiro (00072413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKAI Hiroyasu (00328923)

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10. 佐用博照 (70068302)

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11. 三川潮 (60012613)

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18. 狐塚寛 (60092748)

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19. 濱田昭 (50053781)

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MISAWA Miwa 三澤 美和

Research Projects

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Co-Researchers

Identification of transcription factors of contractile element of bronchial smooth muscle and its change in activity at airway hyperresponsivenessPrincipal Investigator

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Studies on change in airway hyperresponsiveness at bronchial asthma using the technique of RhoA gene manipulationPrincipal Investigator

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Change in RhoA activating mechanism in airway hyperresponsive bronchial smooth muscle.Principal Investigator

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Studies on mechanisms of development of airway hyperresponsiveness in rat bronchial asthmaPrincipal Investigator

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Investigation for the Standardization of Terms on Pharmaceutical Sciences

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[Book] メディカルバイオ2008

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[Book] カッシング薬理学(原著9版)2005

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[Book] カッツング薬理学(原著9版)(監訳)2005

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[Journal Article] Probable involvement of epsilon-isoform of protein kinase C in rat bronchial smooth muscle contraction induced by acetylcholne2008

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[Journal Article] Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyper-responsiveness by inhibiting upregulation of RhoA in rats.2008

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NAID

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[Journal Article] Lovastatin inhibits bronchial hyperresponsiveness by reducing RhoA signaling in rat allergic asthma.2008

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[Journal Article] Lovastatin inhibits bronchial hyperresponsiveness by reducingRhoA signaling in rat allergic asthma.2008

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[Journal Article] Glucocorticoids inhibited airway hyperresponsiveness throughdownregUlation of CPI-17 in bronchial smooth muscle2008

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[Journal Article] Glucoconicoids ameliorate anbigen-induced bronchial smooth musde hyperresponsiveness by inhibiting upregulation or RhoA in rats2008

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[Journal Article] Glucocorticoids inhibited airway hyperresponsiveness through downregulation of CPI-17 in bronchial smooth muscle2008

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MISAWA Miwa 三澤美和