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AWAZU Shoji  粟津 荘司

ORCIDConnect your ORCID iD *help
Researcher Number 60012621
External Links
Affiliation (based on the past Project Information) *help 1996 – 1997: 東京薬科大学, 教授
1988 – 1996: 東京薬科大学, 薬学部, 教授
1993 – 1994: 東京薬科大学, 教授
1992: 東京薬科大, 教授
1991: 東京薬科大学, 教授
1986: Tokyo College of Pharmacy, 薬学部, 教授
1986: Tokyo College of Pharmacy, 教授
Review Section/Research Field
Principal Investigator
Physical pharmacy / Biological pharmacy
Except Principal Investigator
Biological pharmacy / 応用薬理学・医療系薬学 / 医薬分子機能学 / Physical pharmacy
Keywords
Principal Investigator
吸収促進剤 / Caco-2 / 吸収促進 / ペプチド / パイエル板 / Absorption enhancement / Peptide / Caco-2細胞 / タイトジャンクション / 細胞内カルシウム … More / グルコース輸送担体 / ビタミンA / エンケファリン / 吸収改善 / レクチン / 糖付加 / Tight iunction / Intracellular calcium / Glucose transporter / VitaminA / Enkephalin / 粘膜接着 / マイクロスフェア- / 消化管吸収 / Concanavaline A / Coco-2細胞 / ヒト結腸 / 粘膜付着性マイクロカプセル / ポリカーボフィル / 保水効果 / 小腸パイエル板 / エンドサイトーシス / Bioadhensive / Microsphere / Intestinal / Concanvaline A / Peyer's Patch / 肝細胞 / アルブミン / 膜透過性 / 細胞間ルート / 細胞内ルート / 結合タンパク / 骨格筋 / hepatocyte / Albumin / membrane permeability / absorption promoter / paracellular route / transcellular route / binding protein … More
Except Principal Investigator
生理学的薬物速度論 / P-450 / cMOAT / 胆汁排泄 / 薬物速度論 / 薬物間相互作用 / drug delivery / transporter / receptor / tissue targeting / pharmacokinetics / blood-brain barrier / cloning / efflux pump / 薬物代謝酵素 / 酵素の多様性 / 遺伝子発現の調節機構 / 遺伝的多型 / 遺伝子診断法 / 代替法 / 薬物輸送担体 / oatp / cDNAクローニング / 輸送担体 / 尿中排泄 / 薬物代謝 / CYPアイソザイム / 学術用語 / 薬学用語 / 標準化 / Scientific terms / Terms in pharmaceutical sciences / Standerdization / ビタミンA / メトトレキサート / D-グルコース / 消化器障害 / 腸管吸収 / マウス白血病細胞L1210 / 小腸クリプト細胞 / 細胞培養 / マウス肉腫細胞ザルコーマ180 / 小腸粘膜 / 抗癌作用 / 小腸培養細胞IEC-6 / L-ロイシン / メトトレキサ-ト / Dーグルコ-ス / vitamin A / methotrexate / D-glucose / intestinal damage / intestinal absorption / L1210 murine leukemia cell / crypt cell / cell culture / 薬物体内動態 / 生理学的モデル / 細胞膜透過 / 薬物吸収 / 薬物ターゲッティング / ペプチド薬物 / 鎮痛薬 / Pharmacokinetics / Physiological model / Cell membrane permeation / Drug absorption / Drug targeting / Peptide drug / effux pump / ドラッグデリバリー / トランスポーター / レセプター / 組織標的化 / アニマルスケールアップ / 薬物の体内動態 / 動物種差 / 肝機能の局在性 / physiologically based pharmacokinetics / animal scale-up / drug disposition / species difference / uneven distribution of hepatic metabolic enzymes / 薬物毒性 / 肝毒性 / 脂質過酸化 / グルタチオン / 肝細胞 / 肝ミクロソ-ム / 蛍光性物質 / アセトアミノフェン / 蛋白重合体 / 四塩化炭素 / 肝ミクロゾ-ム / 蛍光物質 / 肝ミクロゾーム / 蛍光寿命 / Drug Toxicity / Hepatotoxicity / Lipid Peroxidation / Glutathione / Hepatocyte / Liver Microsome / Fluorescent Substance / Acetaminophen / 細胞間ル-ト / 細胞内ル-ト / 吸収部位差 / Equivalent ポア-半径 / インピ-ダンス解析 / 膜Perturbation / 血流依存性 / 腸管血管同時潅流法 / 空腸 / 結腸 / 吸収促進剤 / Tight junction / アクチン-ミオシンリング / 腸管血菅同時潅流法 / Voltage Clamp法 / 吸収部位血流 / 血管壁透過性 / Eguivalent Pore半径 / 細胞間ルート / 細胞内ルート / 膜perturbation / 血流律速 / 膜透過律速 / Intercellular Route / Transcellular Route / Absorptive Site Difference / Equivalent Pore Radius / Impedance Analysis / Membrane Perturbation / Blood Flow Dependence / Simultaneous Luminal and Vascular Perfusion Less
  • Research Projects

    (13 results)
  • Co-Researchers

    (38 People)
  •  異物解毒の分子基盤:代謝・排泄能の分子から個体への予測

    • Principal Investigator
      杉山 雄一
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  薬物解毒(代謝・排泄)能力の予測:分子から個体へ

    • Principal Investigator
      杉山 雄一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Clarification of organ specific transport mechanism of druge and its application to regulation of pharmacokinetics and pharmacodynamics

    • Principal Investigator
      TSUJI Akira
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kanazawa University
  •  薬物動態の分子基盤:解毒(代謝・排泄)能力の予測

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Prediction and control effectiveness and safety of a drug by means of pharmacokinetics based on physiological and biochemical mechanism of its disposition in body.

    • Principal Investigator
      HANANO Manabu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      医薬分子機能学
    • Research Institution
      Nihon University
  •  Improvemrnt of Drug Absorption in Gastro intestinal TractPrincipal Investigator

    • Principal Investigator
      AWAZU Shoji
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Development of Oral Dosage form for Poorly Absorbable DrugsPrincipal Investigator

    • Principal Investigator
      AWAZU Shojii
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Investigation for the Standardization of Terms on Pharmaceutical Sciences

    • Principal Investigator
      SUGA Tetsuya
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Institution
      Tokyo College of Pharmacy
  •  A Study on Protective Effect of Vitamin A against Antitumour Drug-Induced Damage to Small Intestine

    • Principal Investigator
      HORIE Toshiharu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo College of Pharmacy
  •  Quantitative Evaluation and Prediction of Drug-Toxicity Due to Lipid Peroxidation

    • Principal Investigator
      HORIE Toshiharu
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Physiological and Anatomical Factors Controlling Intestinal Drug Absorption Mechanism

    • Principal Investigator
      HAYASHI Masahiro
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Comprehensive study on the predition of drug disposition based on the physiological and anatomical mechanism.

    • Principal Investigator
      HANANO Manabu
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      University of Tokyo
  •  Factors in Cell Membrane Transport and Tissue Distribution of DrugsPrincipal Investigator

    • Principal Investigator
      AWAZU Shoji
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Tokyo College of Pharmacy
  • 1.  HAYASHI Masahiro (20012669)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  TUJI Akira (10019664)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  SUGIYAMA Yuichi (80090471)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  HORIE Toshiharu (90120154)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  木村 聰城郎 (10025710)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  HANANO Manabu (60012598)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  石崎 高志 (50158747)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  乾 賢一 (70034030)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SUGA Tetsuya (20057318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  RIKIHISA Tadaaki (70012622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  YAMANOUCHI Sakae (20059249)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  YOSHIDA Takemi (20138415)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MISAWA Miwa (20061294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAGAI Tuneji (40061270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TOMIOKA Kiyoshi (50114575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SAMEJIMA Keijiro (00072413)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YATA Noboru (70028835)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TOMITA Mikio (60207610)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MIZUMA Takashi (80229715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MAYUMI Tadanori (00098485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HASHIDA Mitsuru (20135594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  HORI Ryohei (40001036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  FUKUDA Hideomi (50080172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  HOSHI Takeshi (60004537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  IGA Tatsuji (60012663)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐用 博照 (70068302)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  三川 潮 (60012613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  首藤 紘一 (50012612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  北澤 式文 (50026887)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  辻 章夫 (80053784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  寺尾 允男 (60012605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  野村 靖幸 (00034041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  狐塚 寛 (60092748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  濱田 昭 (50053781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  山本 郁男 (50069746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  渡辺 淳 (80080175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  HOSOI Kaoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  三輪 亮寿
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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