Nagao Shizuko 長尾静子

… Alternative Names

NAGAO Shizuko 長尾静子

長尾静子ナガオシズコ

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Researcher Number	20183527
Other IDs
External Links
Affiliation (Current)	2025: 藤田医科大学, 病態モデル先端医学研究センター, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 藤田医科大学, 病態モデル先端医学研究センター, 教授 2019 – 2021: 藤田医科大学, 疾患モデル教育研究サポートセンター, 教授 2018: 藤田医科大学, 疾患モデル教育研究施設, 教授 2017: 藤田保健衛生大学, 研究支援推進センター疾患モデル教育研究施設, 教授 2016 – 2017: 藤田保健衛生大学, 大学共同利用機関等の部局等, 教授 … More 2016: 藤田保健衛生大学, 疾患モデル教育研究施設, 教授 2014 – 2015: 藤田保健衛生大学, 疾患モデル教育研究センター, 教授 2014: 藤田保健衛生大学, 大学共同利用機関等の部局等, 教授 2014: 藤田保健衛生大学, 医学部・疾患モデル教育研究センター, 准教授 2009 – 2014: 藤田保健衛生大学, 疾患モデル教育研究センター, 准教授 2012 – 2013: 藤田保健衛生大学, 大学共同利用機関等の部局等, 准教授 2004 – 2006: 藤田保健衛生大学, 疾患モデル教育研究センター, 講師 1995 – 1996: 藤田保健衛生大学, 総合医科学研究所, 助手 1991 – 1992: 藤田保健衛生大学, 総合医科学研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Experimental pathology / Kidney internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related / Gastroenterology / Urology / Basic Section 59040:Nutrition science and health science-related / Basic Section 52050:Embryonic medicine and pediatrics-related / 広領域 / General surgery
Keywords	Principal Investigator 多発性嚢胞腎症 / 多発性嚢胞腎 / 細胞増殖 / 食塩感受性高血圧 / オミックス解析 / 慢性腎臓病 / マウス / pcy / 嚢胞腎(PKD) / 遺伝的背景 … More / 酸化ストレス / リン酸化プロテオミクス / 情報伝達経路 / PKD / CKD / シグナル伝達 / 網羅的解析 / りん酸化タンパク質 / 塩分摂取 / 環境因子 / メタボローム / リン酸化 / プロテオミクス / メタボロミクス / S6 / polycystic liver / polycystic kidney / 細胞内情報伝達 / 嚢胞 / 線維化 / 核内受容体 / 線維 / SCD1 / TGF / mTOR / ERK / PPAR / Taxotere / Methylprednisolone / Taxol / Aaxol … More Except Principal Investigator 糖尿病性腎症 / 認知機能障害 / 慢性腎臓病 / fibrocystin / 多発性嚢胞腎症 / 脈絡叢の透過性 / キヌレニン / トリプトファン代謝 / 糖尿病性腎臓病 / マクロファージ / CFTR / 2FG-pcy / DBA / Polycystic Kidney / ADPKD / 6FG-pcy / C57BL / ベンゾイソフラノン化合物 / ベンゾイソフラノン誘導体 / ＰＣＫラット / 多発性嚢胞腎 / 膵導管細胞 / PCKラット / 睡眠 / グリアリンパ系 / 芳香族炭化水素受容体 / キヌレン酸 / 同一カロリー摂取 / PFCバランス / 動物モデル / 糖尿病 / 脳由来神経栄養因子（BDNF） / 海馬 / ミクログリア / 大脳皮質 / 腎機能障害 / 血圧 / 肥満2型糖尿病モデル / SDT fattyラット / 嚢胞性腎疾患 / LCMS / グライコミクス / 糖鎖修飾 / 糖鎖バイオマーカー / 細胞増殖 / グルコース代謝 / グライコプロテオミクス / 糖ヌクレオチド / 嚢胞性腎疾患群 / 脳－腎連関 / 一次代謝物 / 脳機能 / 側脳室 / アストログリア / 透過性 / 血液脈絡叢関門 / 脈絡叢 / 尿毒素 / 脳脊髄液 / children / M2-macrophage / macrophage / chronic kidney disease / 間質線維化 / 線維化 / M2型活性化マクロファージ / 活性化マクロファージ / 慢性糸球体腎炎 / 疾患モデル / メタボロミクス / バイオマーカー / トリプトファン / NMDA受容体拮抗薬 / NMDA受容体 / 尿細管障害 / 糖尿性腎臓病 / メタボローム解析 / トリプトファン代謝物 / 血管保護 / CD31 / HIF-1 / NG2 / ペリサイト / HIF / Gag遺伝子 / 内在性レトロウイルス / pericyte / polycystic kidney / cystic fibrosis / SLC26 transporters / Na^+-H^+ exchange (NHE) / HCO_3- transport / water tranport / chronic pancreatitis / センサー分子 / 遺伝子多型 / SLC26 / RNAi / 遺伝子変異 / 嚢胞性線維症 / SLC26輸送担体 / Na^+-H^+交換(NHE) / HCO_3^-輸送 / 水輸送 / 慢性膵炎 / Aneurysms / Animal Models / Genetic Background / Strain Difference / 幼児型嚢胞腎 / 6FGーpcy / マウス / コンジェニック系統 / 成人型嚢胞腎 / Na,KーATPase / 2FGーpcy / Kidney Failure / Spontaneous Animal disease / Polycystic Kidney Disease / Strain difference / Na,K-ATPase / Erythropoietin / Anemia / Congenic Strain / 動脈瘤 / 疾患モデル動物 / 遺伝的背景 / DBA-2FG-pcy / 系統差 / 嚢胞腎 / ＤＮＡメチル化 / 細胞外マトリクス / ラットＰＣＫ / 細胞マトリックス / Primary cilia / primary cilia / 膵管 / PD-1/PD-L1シグナル / co-stimulatory signal / microRNA / 移植・再生医療 / マウス肝移植モデル / MDSC / 骨髄由来免疫抑制細胞 / マイクロRNA / マウス同所性肝移植モデル / 免疫寛容 / 移植免疫 / Panc-1細胞 / 膵液 / Ca^<2+>チャネル / 膵石 / 溶液分泌 / secretin / polycystic kidneyラット / 細胞内Ca^<2+>濃度 / 線毛 / microperfusion / 単離小葉間膵管 / カルシウム輸送体 / 膵導管上皮 / 膵石症 Less

単一遺伝子疾患の病態悪化に拮抗する遺伝子とその情報伝達経路の解明及び治療法の開発Principal Investigator
- Principal Investigator
  
  長尾静子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
Improvement of Cognitive Function by Brain Tissue Clearance Activation in Chronic Kidney Disease
- Principal Investigator
  
  深澤元晶
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
キヌレニン／キヌレン酸を標的とした多発性嚢胞腎症における新規治療薬の開発
- Principal Investigator
  
  釘田雅則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
Significance of rare nucleotide sugar in of cell proliferation of cystic kidney disease
- Principal Investigator
  
  Nakajima Kazuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Gifu University
摂取カロリー同等/PFCバランス不同食の糖尿病性腎臓病と認知機能障害に及ぼす影響
- Principal Investigator
  
  山口太美雄
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Suzuka University of Medical Science
Establichment of control method for M2-type activated macrophage-mediated progression of childhood CKD.
- Principal Investigator
  
  Ikezumi Yohei
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Fujita Health University
The study for the role of tryptophan metabolism in diabetic nephropathy-associated cognitive disorder
- Principal Investigator
  
  Fukasawa Motoaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
Elucidation of the role of tryptophan metabolism in diabetic nephropathy: Towards a development of novel treatment of diabetic nephropathy targeting tryptophan metabolism
- Principal Investigator
  
  Yuzawa Yukio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Fujita Health University
Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.Principal Investigator
- Principal Investigator
  
  NAGAO Shizuko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Fujita Health University
Ameriolation of progression of polycystic kidney disease by stabilization of renal vessel disorders and exploration of endogenous retrovirus responses in macrophages
- Principal Investigator
  
  Ishibashi Michio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nara Medical University
Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-Principal Investigator
- Principal Investigator
  
  Nagao Shizuko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
A study of molecular pathogenesis of chronic pancreatitis by using polycystic kidney rat
- Principal Investigator
  
  ISHIGURO Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Basic studies of therapeutic modality for polycystic kidney disease explored by epigenetic modification of cellular matrix-adhesion proteins
- Principal Investigator
  
  ISHIBASHI MIchio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Nara Medical University
A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascadePrincipal Investigator
- Principal Investigator
  
  SHIZUKO Nagao
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fujita Health University
The clarify of the mechanism of induction of immunological tolerance using mouse liver transplantation model and development of novel immunosuppression.
- Principal Investigator
  
  MORITA Miwa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Research Institute for Child Health and Development
  Fujita Health University
Mechanisms for Ca2+ absorption by pancreatic ductal epithelium : A study looking for a new strategy to prevent pancreatic stone formation.
- Principal Investigator
  
  ISHIGURO Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Molecular pathogenesis of chronic pancreatitis: CFTR and intraductal sensor molecules
- Principal Investigator
  
  NARUSE Satoru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
嚢胞腎モデルにおける細胞増殖抑制剤の治療効果の検討による細胞増殖と細胞の死の解析Principal Investigator
- Principal Investigator
  
  長尾静子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Fujita Health University
2つの嚢胞腎モデルにおける細胞増殖抑制剤,Taxol,の治療効果の検討Principal Investigator
- Principal Investigator
  
  長尾静子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Fujita Health University
Study of the pathogenesis of progressive hereditary PKD mouse
- Principal Investigator
  
  TAKAHASHI Hisahide
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Fujita Health University

[Book] Annual Review 2013腎臓2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄　（分担）
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Treatment of tubular damage in high-fat-diet-fed obese mice using sodium-glucose co-transporter inhibitors2022
- Author(s)
  Saitoh S, Takaki T, Nakajima K, Wo B, Terashima H, Shimo S, Nguyen HB, Thai TQ, Kumamoto K, Kunisawa K, Nagao S, Tojo A, Ohno N, Takahashi K.
- Journal Title
  
  Plos One
  
  Volume: 18 Issue: 2 Pages: e0281770-e0281770
- DOI
  10.1371/journal.pone.0281770
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08266
[Journal Article] Strategy for generation of replication?competent recombinant rotaviruses expressing multiple foreign genes2021
- Author(s)
  Hatazawa Riona、Fukuda Saori、Kumamoto Kanako、Matsushita Fumio、Nagao Shizuko、Murata Takayuki、Taniguchi Koki、Matsui Taei、Komoto Satoshi
- Journal Title
  
  Journal of General Virology
  
  Volume: 102 Issue: 4 Pages: 1-9
- DOI
  10.1099/jgv.0.001587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K07150, KAKENHI-PROJECT-18K07077, KAKENHI-PROJECT-21K08498
[Journal Article] Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease2019
- Author(s)
  Kikuchi Koichi、Saigusa Daisuke、Kanemitsu Yoshitomi、Matsumoto Yotaro、Tsukamoto Hiroki、Abe Takaaki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1835-1835
- DOI
  10.1038/s41467-019-09735-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06651, KAKENHI-PROJECT-18K06742, KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K08198, KAKENHI-PROJECT-18K08199, KAKENHI-PLANNED-17H06394, KAKENHI-PUBLICLY-18H04805, KAKENHI-PROJECT-19H03557, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-17K00856
[Journal Article] Increased salt intake does not worsen the progression of renal cystic disease in high water-loaded PCK rats.2019
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Kazuhiro Nishii, Tamio Yamaguchi.
- Journal Title
  
  PLoS One.
  
  Volume: 14(3) Issue: 3 Pages: e0207461-e0207461
- DOI
  10.1371/journal.pone.0207461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07076, KAKENHI-PROJECT-18K11141
[Journal Article] Distinct oxylipin alterations in diverse models of cystic kidney diseases.2017
- Author(s)
  Md Monirujjamana, Jessay G. Devassy, Tamio Yamaguchi, Nikhil Sidhu, Masanori Kugita, Melissa Gabbs, Shizuko Nagao, Jing Zhou, Amir Ravandi, Harold M. Aukema.
- Journal Title
  
  Biochim Biophys Acta. -Molecular and Cell Biology of Lipids-
  
  Volume: 1862(12) Issue: 12 Pages: 1562-1574
- DOI
  10.1016/j.bbalip.2017.08.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Journal Article] Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease2017
- Author(s)
  Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, Takeda N, Wake M, Honda K, Zhou J, Nangaku M
- Journal Title
  
  Mol Cell Biol
  
  Volume: e-Pub Issue: 24
- DOI
  10.1128/mcb.00337-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K08435, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
[Journal Article] Beneficial effect of combined treatment with octreotide and pasireotide in PCK rats, an orthologous model of human autosomal recessive polycystic kidney disease.2017
- Author(s)
  Masanori Kugita, Kazuhiro Nishii, Tamio Yamaguchi, Atsushi Suzuki, Yukio Yuzawa, Shigeo Horie, Eiji Higashihara, Shizuko Nagao.
- Journal Title
  
  PLoS One.
  
  Volume: 12(5) Issue: 5 Pages: e0177934-e0177934
- DOI
  10.1371/journal.pone.0177934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08435
[Journal Article] Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease2017
- Author(s)
  Hama Taketsugu、Nakanishi Koichi、Sato Masashi、Mukaiyama Hironobu、Togawa Hiroko、Shima Yuko、Miyajima Masayasu、Nozu Kandai、Nagao Shizuko、Takahashi Hisahide、Sako Mayumi、Iijima Kazumoto、Yoshikawa Norishige、Suzuki Hiroyuki
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 313 Issue: 6 Pages: F1223-F1231
- DOI
  10.1152/ajprenal.00697.2016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09694, KAKENHI-PROJECT-17K10150, KAKENHI-PROJECT-17K16278, KAKENHI-PROJECT-15K08435, KAKENHI-PROJECT-15K09695
[Journal Article] 多発性嚢胞腎発症のメカニズム2013
- Author(s)
  長尾静子、釘田雅則、吉原大輔、山口太美雄
- Journal Title
  
  Annual Review 2013 腎臓 (冨野康日己、柏原直樹、成田一衛編、中外医学社、東京)
  
  Pages: 101-108
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Structure and function of the pancreas in the polycystic kidney rat2012
- Author(s)
  Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H
- Journal Title
  
  Pancreas
  
  Volume: (in press) Issue: 8 Pages: 1292-8
- DOI
  10.1097/mpa.0b013e31824c12f9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590332, KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-24591010
[Journal Article] PPARγ agonists in polycystic kidney disease with frequent development of cardiovascular disorders.2012
- Author(s)
  Shizuko Nagao, Yamaguchi T.
- Journal Title
  
  Current Molecular Pharmacology
  
  Volume: Vol.5, No.2 Pages: 292-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Structure and Function of the Pancreas in the Polycystic Kidney Rat2012
- Author(s)
  Yi L., Naruse S., Furuya S., Yamamoto A., Nakakuki M., Nagao S., Yoshihara D., Ko S.B.H., Wei M, Kondo T., Ishiguro H.
- Journal Title
  
  Pancreas
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-γ agonistsin polycystic kidney disease with frequent development of cardiovascular disorders2012
- Author(s)
  Nagao S, Yamaguchi T
- Journal Title
  
  Curr MolPharmacol
  
  Volume: 5(2) Pages: 292-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in PPAR-γ agonist-treated kidneys in an orthologous rat model of human autosomal recessive polycystic kidney disease2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema H.M., Kurahashi H., Morita M., Hiki Y., Calvet J.P., Wallace D.P., Toyohara T., TAbe T., Nagao S.
- Journal Title
  
  PPAR Research
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease2012
- Author(s)
  Nagao S, Kugita M, Yoshihara D, Yamaguchi T
- Journal Title
  
  Exp Anim.
  
  Volume: 61(5) Pages: 477-88
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Intraspinal MAP1B : A Novel Therapeutic Target for Alzheimer's Disease?2012
- Author(s)
  Mitsuyama Y., Futatsugi Y., Okuya M., Kawase T., Karagiozov K., Kato Y., Kanno T., Sano H., Nagao S., Koide T., Manabe T., Mitsuyama F.
- Journal Title
  
  International Journal of Alzheimer's Disease
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Animal models for human polycystic kidney disease.2012
- Author(s)
  Shizuko Nagao, Kugita M, Yoshihara D, Yamaguchi T.
- Journal Title
  
  Experimental Animal
  
  Volume: Vol.61, No.5 Pages: 477-488
- NAID
  10031121852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Stimulation-dependent intraspinal microtubules and synaptic failure in Alzheimer's disease: a review2012
- Author(s)
  Mitsuyama F, Futatsugi Y, Okuya M, Kawase T, Karagiozov K, Kato Y, Kanno T, Sano H, Nagao S, Koide T
- Journal Title
  
  Int JAlzheimers Dis
  
  Volume: 2012 Pages: 519682-519682
- DOI
  10.1155/2012/519682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global Gene ExpressionProfiling in PPAR-γ Agonist-TreatedKidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease.2012
- Author(s)
  Yoshihara D, Kugita M, Yamaguchi T, Aukema HM, Kurahashi H, Morita M, Hiki Y, Calvet JP, Wallace DP, Toyohara T, Abe T, Nagao S.
- Journal Title
  
  PPAR Res
  
  Volume: 2012 Pages: 695898-695898
- DOI
  10.1155/2012/695898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351, KAKENHI-PUBLICLY-23013019, KAKENHI-PROJECT-23659182, KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-24790393
[Journal Article] Metabolomic profiling of the autosomal dominant polycystic kidney disease rat model2011
- Author(s)
  Toyohara T, Suzuki T, Akiyama Y, Yoshihara D, Takeuchi Y, Mishima E, Nagao S, Soga T, Abe T
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15(5) Issue: 5 Pages: 676-87
- DOI
  10.1007/s10157-011-0467-4
- NAID
  10030340950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-22790144, KAKENHI-PROJECT-23590265
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M, Nishii K, Morita M, Yoshihara D, Kowa-Sugiyama H, Yamada K, Yamaguchi T, Wallace DP, Calvet JP, Kurahashi H, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Global gene expression profiling in early-stage polycystic kidney disease in the Han : SPRD Cy rat identifies a role for RXR signaling.2011
- Author(s)
  Kugita M., Nishii K., Morita M., Yoshihara D., Kowa-Sugiyama H., Yamada K., Yamaguchi T., Wallace D.P., Calvet J.P., Kurahashi H., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D, Kurahashi H, Morita M,Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] PPAR-{gamma} agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema HM., Yamaguchi T., Calvet JP., Wallace DP., Nagao S.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Epithelial-to-mesenchymal transition in cyst lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011
- Author(s)
  Togawa H, Nakanishi K, Mukaiyama H, Hama T, Shima Y, Sako M, Miyajima M, Nozu K, Nishii K, Nagao S, Takahashi H, Iijima K, Yoshikawa N.
- Journal Title
  
  Am J Physiol RenalPhysiol
  
  Volume: 300(2) Pages: 511-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Epithelial-to-mesenchymal transition in cyst lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011
- Author(s)
  Togawa H, Nakanishi K, Mukaiyama H, Hama T, Shima Y, Sako M, Miyajima M, Nozu K, Nishii K, Nagao S, Takahashi H, Iijima K, Yoshikawa N.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Phosphate overload induces podocyte injury via type III Na-dependent phosphate transporter.2011
- Author(s)
  Sekiguchi S, Suzuki A, Asano S, Nishiwaki-Yasuda K, Shibata M, Nagao S, Yamamoto N, Matsuyama M, Sato Y, Yan K, Yaoita E, Itoh M.
- Journal Title
  
  Am J Physiol RenalPhysiol
  
  Volume: 300(4) Issue: 4 Pages: 848-856
- DOI
  10.1152/ajprenal.00334.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351, KAKENHI-PROJECT-22591970
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Polycystic kidney disease in Han : SPRD Cy rats is associated with elevated expression and mislocalization of SamCystin.2010
- Author(s)
  Nagao S, Morita M, Kugita M, Yoshihara D, Yamaguchi T, Kurahashi H, Calvet JP, Wallace DP.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590351
[Journal Article] Structure and function of the pancreas in the polycystic kidney rat
- Author(s)
  Yi L, Naruse S, Furuya S, Yamamoto A, Nakakuki M, Nagao S, Yoshihara D, Ko SB, Wei M, Kondo T, Ishiguro H.
- Journal Title
  
  Pancreas
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590873
[Patent] 染色体優性多発性膿胞腎の判定方法および予防2010
- Inventor(s)
  阿部高明、長尾静子、曽我朋義
- Industrial Property Rights Holder
  東北大学
- Acquisition Date
  2010-11-24
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症の遺伝子変異に基づく新規モデルマウスの作成2023
- Author(s)
  釘田雅則、亀井優香、坂田美和、熊本海生航、吉村文、白水貴大、長尾静子
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-22K08345
[Presentation] 糖尿病性腎症モデルラットにおける側脳室微小環境と脳機能の関連についての検討2022
- Author(s)
  深澤元晶、高野一輝、長尾静子、髙橋和男
- Organizer
  第54回藤田医科大学医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08621
[Presentation] 常染色劣性多発性嚢胞腎症モデル動物PCKラットの腎臓におけるトリプトファン代謝産物の解析2022
- Author(s)
  釘田雅則, 熊本海生航, 吉村文, 白水貴大, 藤垣英嗣, 山本康子, 高橋和男, 湯澤由紀夫, 長尾静子
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08345
[Presentation] 糖尿病性腎症モデル動物における脳機能の解析2021
- Author(s)
  深澤元晶、高野一輝、長尾静子、高橋和男
- Organizer
  第53回藤田医科大学医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K08621
[Presentation] 同一摂取カロリーでラードとスクロースの比率を高めた場合の非肥満糖尿病マウスの血糖動態と腎傷害発現2020
- Author(s)
  吉村文, 山口太美雄, 釘田雅則, 熊本海生航, 塩竈和也, 荻津直通, 三浦俊宏, 米田操, 長村洋一, 長尾静子
- Organizer
  第63回日本腎臓学会学術総会、横浜、2020年8月19日～21日、パシフィコ横浜　アネックスホール
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 食塩感受性高血圧の遺伝的背景を持つ新規ARPKDモデル動物2020
- Author(s)
  吉村文、釘田雅則、熊本海生航、坂田美和、長尾静子
- Organizer
  第63回日本腎臓学会学術総会、横浜、2020年8月19日～21日、パシフィコ横浜　アネックスホール
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎症モデルラットの腎臓における一次繊毛の形態変化2020
- Author(s)
  熊本海生航、齊藤成、大野伸彦、鏡裕行、釘田雅則、吉村文、長尾静子
- Organizer
  第67回日本実験動物学会総会、誌上開催
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Comparison of the effect of calorie matched high saturated-fat and high unsaturated-fat diets on lysosomal renal injury in non-obese, streptozotocin-injected CD-1 mice.2020
- Author(s)
  Tamio Yamaguchi, Aya Yoshimura, Masanori Kugita, Kanako Kumamoto, Kazuya Shiogama, Kyongtae T. Bae, Shizuko Nagao
- Organizer
  Kidney week, 2020, Denver, U.S.A., 2020 Oct 19-25.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Long-term effect of novel morphometric 3D capsule device to constrain growth in polycystic kidney: comparison between wild-type, Cy/+ and PCK rat models.2020
- Author(s)
  Kyongtae T. Bae, Aya Yoshimura, Kanako Kumamoto, Masanori Kugita, Tamio Yamaguchi, Shigeo Horie, Junu Bae, Shizuko Nagao
- Organizer
  Kidney week, 2020, Denver, U.S.A., 2020 Oct 19-25.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] ラット人工肛門モデルにおける、人工肛門への便注入療法の有用性の検討　第二報2020
- Author(s)
  宇賀菜緒子、土屋智寛、近藤靖浩、直江篤樹、渡邉俊介、安井稔博、鈴木達也、　常陸圭介、土田邦博、吉村文、熊本海生航、長尾静子
- Organizer
  日本小児外科学会　2020年9月19日～21日、東京、都市センターホテル
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 糖尿病性腎症における代謝変容の役割の解明2019
- Author(s)
  高橋和男、坪井直毅、長尾静子、齋藤邦明、湯澤由紀夫
- Organizer
  第49回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] 多発性嚢胞腎症モデル動物PCKラットにおける嚢胞形成関連代謝産物の探索2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Alteration of Tryptophan-Kynurenine Metabolites in the Serum and Kidney in Diabetic Nephropathy2019
- Author(s)
  Shoko Matsushita,Kazuo Takahashi,Ryosuke Umeda,Naotake Tsuboi,Kazuki Nakajima,1 Aya Yoshimura,1 Kanako Kumamoto,1 Masanori Kugita,1 Hidetsugu Fujigaki,1 Akihiro Mouri,1 Yasuko Yamamoto,1 Toshitaka Nabeshima,Mitsutoshi Setou,Shizuko Nagao,Kuniaki Saito,Yukio Yuzawa
- Organizer
  Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] 種類の繊毛病モデル動物を用いた多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] SBF-SEM画像によるラット腎臓組織集合管主細胞一次繊毛長のボクセル計測法2019
- Author(s)
  齊藤成、熊本海生航、大野伸彦、高橋和男、長尾静子
- Organizer
  第125回日本解剖学会学術集会、（紙上開催）
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 2型糖尿病性腎症モデルラットにおける腎組織中キノリン酸の分布解析2019
- Author(s)
  松下祥子、高橋和男、吉村文、熊本海生航、伊藤辰将、坪井直毅、毛利彰宏3、山本　康子4、藤垣　英嗣4、中嶋和紀、釘田雅則、國澤和生、鍋島俊隆、齋藤邦明、瀬藤光利、長尾静子、湯澤由紀夫
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08715
[Presentation] Voxel-based morphometry of images acquired through SBF-SEM of primary cilia from a rat kidney collecting duct.2019
- Author(s)
  Sei Saitoh, Kanako Kumamoto, Nobuhiko Ohno, Shizuko Nagao.
- Organizer
  The 13th Japan-China Joint Seminar on Histochemistry and Cytochemistry, 2019, Kobe, Hyogo, Japan, Sep 19-21.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 常染色体劣性多発性嚢胞腎疾患（ARPKD）モデル動物における一次繊毛長と形態に治療が与える影響について2019
- Author(s)
  熊本海生航、齊藤成、大野伸彦、服部宣子、釘田雅則、吉村文、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Sox2/CD63-GFPトランスジェニックラットの腎病態について2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 常染色体劣性多発性嚢胞腎疾患(ARPKD)モデル動物の腎臓におけるG protein-coupled receptorの刺激が一次繊毛長と形態に与える影響について2019
- Author(s)
  熊本海生航、齊藤成、大野伸彦、服部宣子、釘田雅則、吉村文、長尾静子
- Organizer
  第90回東海実験動物研究会、名古屋、2019年6月29日、名古屋市立大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] NG2活性化による腎髄質ペリサイト機能温存とラットPCK多発性嚢胞腎モデルにみられる糸球体病変の軽減2019
- Author(s)
  熊本海生航、釘田雅則、吉村文、藤本清秀、千原良友、小島直人、東原英二、長尾静子、石橋道男
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 腎性尿崩症様病態を示す新規トランスジェニックラット2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、長尾静子
- Organizer
  第62回日本腎臓学会学術総会、名古屋、2019年6月21日～23日、名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] NG2活性化による腎髄質ペリサイト機能温存とラットPCK 多発性嚢胞腎モデルにみられる糸球体病変の軽減2019
- Author(s)
  熊本海生航、釘田雅則、吉村文、藤本清秀、千原良友、小島直人、東原英二、長尾静子、石橋道男
- Organizer
  第62回日本腎臓学会学術総会、2019年6月21日　名古屋
- Data Source
  KAKENHI-PROJECT-16K11058
[Presentation] エクソソームマーカーCD63-GFPを腎臓で発現するトランスジェニックラット2019
- Author(s)
  吉村文、熊本海生航、釘田雅則、大平圭悟、落谷孝広、長尾静子
- Organizer
  第6回日本細胞外小胞学会、東京、2019年10月24日～25日、国立がん研究センター研究所
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Development and implantation of novel morphometric 3D capsule device to constrain structural change of polycystic kidney: a feasibility study in a rat model.2019
- Author(s)
  Kyongtae T. Bae#, Kanako Kumamoto#, Aya Yoshimura#, Masanori Kugita, Shigeo Horie, Tamio Yamaguchi, Junu T. Bae, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Comparison study of calorie matched high fat and high sugar diets on renal injury with lysosomal dysfunction in pre-diabetic mice.2019
- Author(s)
  Aya Yoshimura#, Tamio Yamaguchi#, Masanori Kugita#, Kanako Kumamoto, Kazuya Shiogama, Naomichi Ogitsu, Toshihiro Miura, Misao Yoneda, Yoichi Nagamura, Shizuko Nagao (# equal author)
- Organizer
  Kidney week, 2019, Washington, DC, U.S.A., Nov 5-10.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] ネフロン癆モデル動物pcyマウスの多発性嚢胞腎における代謝産物の網羅的解析2019
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第66回日本実験動物学会総会、福岡、2019年5月15日～17日、福岡国際会議場
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 3D architectures of primary cilia of collecting duct cells in rat kidney revealed by SBF-SEM2019
- Author(s)
  齊藤成、熊本海生航、大野伸彦、高橋和男、長尾静子
- Organizer
  第79回日本解剖学会中部支部学術集会、松本、2019年10月19日～20日、松本歯科大学
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 糖尿病モデルマウスにおけるキヌレニン経路代謝物の腎組織イメージング質量分析2018
- Author(s)
  松下祥子、高橋和男、伊藤辰将、山本康子、藤垣英嗣、毛利彰宏、中嶋和紀、尾之内高慶、辰川英樹、釘田雅則、長尾静子、人見清隆、齋藤邦明、瀬藤光利、湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Glucose metabolic profiles in renal tissue of an orthologous PCK rat model of human PKD using metabolic and proteomic analyses.2018
- Author(s)
  Shizuko Nagao, Masanori Kugita, Kanako Kumamoto, Aya Yoshimura, Tamio Yamaguchi, Kazuki Nakajima, Kazuo Takahashi, Yukio Yuzawa
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] 多発性嚢胞腎ラットへの低分子化合物NK0070投与によるNG2 pericyte マーカーの温存と腎病変2018
- Author(s)
  石橋道男、釘田雅則、熊本海生航、吉村　文、藤本清秀、東原英二、長尾静子
- Organizer
  第４８回日本腎臓学会東部学術大会、平成30年（2018）10月20日~21日、東京
- Data Source
  KAKENHI-PROJECT-16K11058
[Presentation] 多発性嚢胞腎症モデルPCKラットの腎臓におけるメタボローム解析―グルコース代謝経路についてー2018
- Author(s)
  釘田雅則、熊本海生航、吉村　文、山口太美雄、長尾静子
- Organizer
  第65回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Role of Retinoid X receptor pathway in cystogenesis with therapeutic potential in polycystic kidney disease.2018
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Harold M Aukema, Kazuhiro Nishii and Shizuko Nagao
- Organizer
  ISN Frontiers Meetings 2018, Tokyo, JAPAN, 2018 Feb 22-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 糖脂質合成酵素阻害剤はグルコース代謝を介してADPKDの病態を抑制する2018
- Author(s)
  中嶋和紀、石橋洋平、釘田雅則、中尾静羽、高橋和男、永松正、長尾静子、湯澤由紀夫
- Organizer
  第61回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Renal and serum oxylipin alterations in the jck mouse, an orthologous model of human nephronophthisis.2018
- Author(s)
  Tamio Yamaguchi, Md Monirujjaman, Jessay G. Devassy, Melissa Gabbs, Nikhil Sidhu, Arumi Jha, Andrew J. Halayko, Masanori Kugita, Shizuko Nagao, Amir Ravandi, Harold M. Aukema
- Organizer
  ISN Frontiers Meetings 2018, Tokyo, JAPAN, 2018 Feb 22-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物PCKラットの腎臓における代謝産物解析－中心炭素代謝経路について－2018
- Author(s)
  釘田雅則、熊本海生航、吉村文、中嶋和紀、高橋和男、湯澤由紀夫、長尾静子
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Mitochondrial Morphological Abnormality in Cyst Epithelial Cells of Autosomal Dominant Polycystic Kidney Disease Patients.2018
- Author(s)
  Yu Ishimoto, Akira Shimizu, Masanori Kugita, Shizuko Nagao, Kenjiro Honda, Reiko Inagi, Masanomi Nangaku, Saori Nishio, Haruna Kawano, Shigeo Horie, Tomoko Kasahara, Kenji Osafune, Junichi Hoshino, Yoshifumi Ubara
- Organizer
  Kidney week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07076
[Presentation] Kidney Glycosphingolipidomics and Metabolomics Reveal Metabolic Crosstalk between Elevated Glycosphingolipids and Glucose Metabolisms in PKD Progression.2017
- Author(s)
  Kazuki Nakajima, Kazuo Takahashi, Masanori Kugita, Shizuko Nagao, Yukio Yuzawa
- Organizer
  Kidney week 2017, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Suppressive Effect of RXR Ligand and MEK Inhibitor on RXR Expression and Cellular Proliferation in Immortalized Polycystic Kidney Cells.2017
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Kazuhiro Nishii, Mai Sasaki, Noboru Ogiso, Harold M. Aukema, Shizuko Nagao
- Organizer
  Kidney week 2017, New Orleans, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Altered Liver Bioactive Lipid (Oxylipin) Profiles in PCK Rats with Polycystic Kidney and Liver Disease.2017
- Author(s)
  Tamio Yamaguchi, Jessay G. Devassy, Aruni Jha, Andrew J Halayko, Masanori Kugita, Shizuko Nagao, Amir Ravandi, Harold M Aukema
- Organizer
  Kidney week 2017, New Orleans, LA, U.S.A., 2017 Oct 31-Nov 5
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] アルツハイマー病治療に向けて-血液からのAβ除去による認知機能改善効果-2016
- Author(s)
  川口　和紀、坂田　美和、酒井　一由、比企　能之、加藤　政雄、長尾　静子、間宮　隆吉、鍋島　俊隆、北口　暢哉
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京　東京国際フォーラム
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Differential expressions of miR-378a-3p/ADAMTS1 in cpk mice, a model of ARPKD2016
- Author(s)
  Masashi Sato, Koichi Nakanishi, Taketsugu Hama, Hironobu Mukaiyama, Hiroko Togawa, Yuko Shima, Masayasu Miyajima, Kandai Nozu, Shizuko Nagao, Hisahide Takahashi, Kazumoto Iijima, Norishige Yoshikawa and Hiroyuki Suzuki.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるレチノイドX受容体の解析2016
- Author(s)
  釘田雅則、吉原大輔、加藤由布、小木曽昇、下村恭代、西田修、長尾静子
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  神奈川県、川崎　　ミューザ川崎シンフォニーホール
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 血中アミロイドβ蛋白(Aβ)除去によるアルツハイマー病治療システム；ラット血中Aβ除去による血液・髄液中Aβの変化2016
- Author(s)
  川口和紀、木野村淳、平林晃知、渡辺康太、青木洋樹、榊原由莉、坂田美和、釘田雅則、加藤政雄、長尾静子、北口暢哉
- Organizer
  第6回日本認知症予防学会学術集会
- Place of Presentation
  宮城県、仙台　東北大学百周年記念会館川内萩ホール
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Increased salt intakes dose not deteriorate renal cystic disease progression in high water loaded PCK rats.2016
- Author(s)
  Masanori Kugita, Tamio Yamaguchi, Yoichi Nagamura, Harold M Aukema, Shizuko Nagao.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 組織再生促進デバイス：細胞と天然高分子粉体との混合物による成長因子産生能の検討2016
- Author(s)
  堀秀生、新里昌功、新美元、長尾静子、比企能之、北口暢哉
- Organizer
  第54回日本人工臓器学会大会
- Place of Presentation
  鳥取県　米子　米子コンベンションセンター(BIG SHIP)
- Year and Date
  2016-11-23
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] ミトコンドリア機能異常は多発性嚢胞腎の嚢胞形成に関与する2016
- Author(s)
  石本遊、南学正臣、吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川県、横浜　パシフィコ横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Mitochondrial dysfunction contributes to cysts proliferation of autosomal dominant polycystic kidney disease.2016
- Author(s)
  Yu Ishimoto, Masaomi Nangaku, Masanori Kugita, Shizuko Nagao, Akira Shimizu, Jing Zhou, Reiko Inagi.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Mitochondrial dysfunction contributes to cyst proliferation of autosomal dominant polycystic kidney disease.2016
- Author(s)
  Yu Ishimoto, Masaomi Nangaku, Shizuko Nagao, Daisuke Yoshihara, Masanori Kugita, Yoko Yoshida, Jing Zhou, Mike Murphy, Akira Shimizu, Reiko Inagi.
- Organizer
  The Asian Pacific Society of Nephrology
- Place of Presentation
  Perth, WA, Australia
- Year and Date
  2016-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるRXRの発現と局在2016
- Author(s)
  吉原大輔、釘田雅則、長尾静子
- Organizer
  第59回日本腎臓学会学術総会
- Place of Presentation
  神奈川県、横浜　パシフィコ横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Bioactive Lipid Alterations in the jck and pcy mouse models of nephronophthisis.2016
- Author(s)
  Tamio Yamaguchi, Nikhil Sidhu, Jessay Gopuran Devassy, Melissa Gabbs, Amir Ravandi, Masanori Kugita, Shizuko Nagao, Harold M. Aukema.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago, IL, U.S.A.
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Beneficial effect of combined treatment of two somatostatin analogs in an orthologous model of human autosomal recessive polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nishii K, Suzuki A, Higashihara E, Horie S, Yamaguchi T, Nagao S.
- Organizer
  1th ASPR Congress & the 118th Annual Meeting of the Japan Pediatric Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-15
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Retinoid X receptor pathway, a novel signaling cascade responsible for cystogenesis in three rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Aukema HM, Yamaguchi T, Nagao S.
- Organizer
  American Society of Nephrology Kidney Week 2015
- Place of Presentation
  San Diego, CA, U.S.A.
- Year and Date
  2015-11-03
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎症のモデル動物であるPCKラットにおけるGi作動薬の病態進行抑制効果2015
- Author(s)
  釘田雅則、吉原大輔、西井一宏、鈴木敦詞、湯澤由紀夫、山口太美雄、堀江重郎、東原英二、長尾静子
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] であるPCKラットにおけるGi作動薬の病態進行2015
- Author(s)
  吉原大輔、釘田雅則、西井一宏、鈴木敦詞、湯澤由紀夫、東原英二、堀江重郎、山口太美雄、長尾静子
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] Expression and distribution of retinoid X receptor in rodent models of polycystic kidney disease.2015
- Author(s)
  Yoshihara D, Kugita M, Sasaki M, Nagao S.
- Organizer
  11th ASPR Congress & the 118th Annual Meeting of the Japan Pediatric Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-15
- Data Source
  KAKENHI-PROJECT-15K08435
[Presentation] 多発性嚢胞腎の動物モデル2013
- Author(s)
  長尾静子 (枝澄香)、釘田雅則、吉原大輔、山口多美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD)2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] トピックスセッション1「膵疾患の克服を目指した基礎研究」　膵導管細胞管腔膜のカルシウム輸送とメカノセンサー機能2013
- Author(s)
  石黒真理子、山本明子、長尾枝澄香、成瀬　達、石黒　洋
- Organizer
  第44回日本膵臓学会大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591010
[Presentation] テルミサルタンによるヒト常染色体劣性多発性嚢胞腎症オーソログ遺伝子変異モデルにおける病態発現抑制効果2013
- Author(s)
  長尾静子(枝澄香)、吉原大輔、釘田雅則、佐々木麻衣、堀江重郎、中西浩一、阿部高明、山口太美雄
- Organizer
  第48回日本小児腎臓学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎の動物モデル.2013
- Author(s)
  長尾静子(枝澄香)、釘田雅則、吉原大輔、山口太美雄
- Organizer
  第60回日本実験動物学会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Ameliorative effect of telmisartan on fibrocystic liver disease progression in an orthologous rat model of human autosomal recessive polycystic kidney disease (ARPKD).2013
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Mai Sasaki, Shigeo Horie, Koichi Nakanishi, Takaaki Abe, Harold M. Aukema, Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  World Congress of Nephrology2013
- Place of Presentation
  HongKong, China
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング.2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子(枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎（PKD）上皮細胞におけるCa2+輸送低下および細胞内cAMP増加に関わるシグナル伝達2012
- Author(s)
  長尾静子 (枝澄香)
- Organizer
  2012年度生理研研究会『粘膜防御における上皮膜輸送の役割』
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓における retinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子(枝澄香)
- Organizer
  日本実験動物科学・技術九州 2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model of human ARPKD2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara, Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] HikiExtracorporeal A β Removal System(EARS) for Alzheimer' s Disease therapy: Novel Devices with fragments of hollow fibers removed Aβ effectively both in vitro and invivo.2012
- Author(s)
  Nobuya Kitaguchi, Takehiro Gotoh, Kazunori Kawaguchi1, Hideo Hori, Atsushi Ohashi, Shigeru Nakai, Shizuko Nagao, Shinji Ito, Tatsuro Mutoh, Yukio Yuzawa, Yoshiyuki
- Organizer
  Alzheimer's Association International Conference 2012
- Place of Presentation
  Vancouver, British Columbia. Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan ameliorates fibrocystic liver disease in PCK rats, an orthologous model ofhuman ARPKD.2012
- Author(s)
  Masanori Kugita, Daisuke Yoshihara,Shigeo Horie, Harold M Aukema, Tamio Yamaguchi, Shizuko Nagao
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKにおけるテルミサルタンの病態発現抑制効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子 (枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Telmisartan Ameliorates Fibrocystic Liver Disease in an Orthologous Rat Model of Human ARPKD2012
- Author(s)
  Daisuke Yoshihara, Masanori Kugita, Shigeo Horie, Harold M. Aukema,Tamio Yamaguchi, Shizuko Nagao.
- Organizer
  American Society of Nephrology Kidney Week 2012
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ラット多発性嚢胞腎におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2012
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾静子 (枝澄香)
- Organizer
  第55回日本腎臓学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Extracorporeal Aβ Removal System (EARS) for Alzheimer’s Disease therapy: Novel Devices with fragments of hollow fibers removed Aβ effectively both in vitro and in vivo2012
- Author(s)
  Nobuya Kitaguchi, Takehiro Gotoh, Kazunori Kawaguchi1, Hideo Hori, Atsushi Ohashi, Shigeru Nakai, Shizuko Nagao, Shinji Ito, Tatsuro Mutoh, Yukio Yuzawa, Yoshiyuki Hiki
- Organizer
  Alzheimer's Association International Conference 2012
- Place of Presentation
  Vancouver, British Columbia. Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデル動物の腎臓におけるretinoid X receptor (RXR)の発現と局在2012
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾静子 (枝澄香)
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患におけるPPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔, 釘田雅則, 山口太美雄, 長尾静子 (枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 検定交配における画像診断の有用性2012
- Author(s)
  羽根田千江美、鈴木昇一、長尾静子(枝澄香)、松山睦司
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎(PKD)上皮細胞における Ca2+輸送低下および細胞内 cAMP 増加に関わるシグナル伝達.2012
- Author(s)
  長尾静子(枝澄香)
- Organizer
  2012 年度生理研研究会『粘膜防御における上皮膜輸送の役割』
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞性疾患における PPARγ部分作動薬の治療効果2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第44回藤田医学会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCKにおけるテルミサルタンの病態発現抑制効果.2012
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、長尾静子(枝澄香)
- Organizer
  第20回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 網羅的遺伝子発現解析を用いた多発性嚢胞腎ラットPCKにおけるPPARγアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PPAE-γ agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease2011
- Author(s)
  Daisuke Yoshihara., Hiroki Kurahashi., Miwa Morita., Masanori Kugita., Yoshiyuki Hiki., Harold M.Aukema., Tamio Yamaguchi., James P.Calvet, Darren P.Wallace., Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-γ agonist-treated PCK rats, an orthologous model of human ARPKD.2011
- Author(s)
  Yoshihara D, Kugita M, Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T, Abe T, Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition 2011
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] cpk マウスにおける部位特定的リン酸化 Smad3 の発現2011
- Author(s)
  浜武継、中西浩一、向山弘展、戸川寛子、島友子、宮嶋正康、高橋久英、長尾枝澄香(静子)、飯島一誠、吉川徳茂
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 羅的遺伝子発現解析を用いた多発性嚢胞腎ラット PCK における PPAR-γアゴニストによる治療機序の検証2011
- Author(s)
  吉原大輔、釘田雅則、倉橋浩樹、森田美和、比企能之、山口太美雄、豊原敬文、阿部高明、長尾枝澄香(静子)
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 北口暢哉生分解性不織布デバイスによる慢性腎不全モデルラットの治療効果.2011
- Author(s)
  堀秀生、川口和紀、大橋篤、新里昌功、森田美和、長尾枝澄香(静子)
- Organizer
  日本医工学治療学会第27回学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラット PCK の腎臓における PPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PPAR-γagonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease.2011
- Author(s)
  Daisuke Yoshihara, Hiroki Kurahashi, M iwa Morita, Masano r i K ugit a, Yoshiyuki Hiki, Harold M Aukema, Tamio Yamaguchi, James P Calvet, Darren PWallace, Shizuko Nagao.
- Organizer
  World Congress of Nephrology 2011
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXR は嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] RXRは嚢胞形成機序における共通の因子か?2011
- Author(s)
  釘田雅則、吉原大輔、山口太美雄、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Global gene expression profiling in kidneys of PPAR-gamma agonist-treated PCK rats, an orthologous model of human ARPKD2011
- Author(s)
  Yoshihara D., Kugita M., Kurahashi H, Morita M, Hiki Y, Yamaguchi T, Aukema HM, Wallace DP, Calvet JP, Toyohara T., Abe T., Nagao S.
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Wallace Darren 多発性嚢胞腎症モデルであるj ckマウスの特徴.2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットPCKの腎臓におけるPPARγアゴニスト投与の治療効果に関する網羅的遺伝子発現プロファイリング2011
- Author(s)
  吉原大輔、釘田雅則、山口太美雄、倉橋浩樹、長尾枝澄香(静子)
- Organizer
  第43回藤田医学会総会
- Place of Presentation
  豊明、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Metabolomic Profiling of the Autosomal Dominant Polycystic Kidney Disease Rat Model2011
- Author(s)
  Takafumi Toyohara, Takehiro Suzuki, Yasutoshi Akiyama, Daisuke Yoshihara, Eikan Mishima, Yoichi Takeuchi, Sadayoshi Ito, Shizuko Nagao, Tomoyoshi Soga, Takaaki Abe
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] cpkマウスにおける部位特定的リン酸化Smad3の発現2011
- Author(s)
  浜武継、中西浩一、向山弘展、戸川寛子、島友子、宮嶋正康、高橋久英、長尾枝澄香(静子)、飯島一誠、吉川徳茂
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Acceleration of Smad3 phosphorylation at linker regions via c-Jun NH2-terminal kinase (JNK) in cyst-lining epithelial cells in cpk mouse, a model of ARPKD2011
- Author(s)
  Mukaiyama H., Nakanishi K., Hama T., Togawa H., Shima Y., Miyajima M., Takahashi H., Nagao S., Iijima K., Yoshikawa N
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおけるPPAE-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎症モデルであるjckマウスの特徴2011
- Author(s)
  長尾枝澄香(静子)、吉原大輔、釘田雅則、森田美和、山口太美雄、Wallace Darren
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Acceleration of Smad3 phosphorylation at linker regions via c-Jun NH2-terminal kinase (JNK) in cyst-lining epithelial cells in cpk mouse, a model of ARPKD.2011
- Author(s)
  Mukaiyama H, Nakanishi K, Hama T, Togawa H, Shima Y, Miyajima M, Takahashi H, Nagao S, Iijima K, Yoshikawa N
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition 2011
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Metabolomic Profiling of the Autosomal Dominant Polycystic Kidney Disease Rat Model.2011
- Author(s)
  Takafumi Toyohara, Takehiro Suzuki,Yasutoshi Akiyama, Daisuke Yoshihara, Eikan Mishima, Yoichi Takeuchi, Sadayoshi Ito, Shizuko Nagao, Tomoyoshi Soga, Takaaki Abe
- Organizer
  American Society of Nephrology 44th Annual Meeting & Scientific Exposition 2011
- Place of Presentation
  Philadelphia, PA USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 生分解性不織布デバイスによる慢性腎不全モデルラットの治療効果2011
- Author(s)
  堀秀生、川口和紀、大橋篤、新里昌功、森田美和、長尾枝澄香(静子)、北口暢哉
- Organizer
  日本医工学治療学会第27回学術大会
- Place of Presentation
  岡山、日本
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト多発性嚢胞腎症のラットモデルにおける PPAR-γアゴニストの治療効果2011
- Author(s)
  吉原大輔、倉橋浩樹、森田美和、釘田雅則、比企能之、Aukema Harold、山口太美雄、Calvet James、Wallace Darren、長尾枝澄香(静子)
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト ARPKD と相同遺伝子変異を有する PCK rat における上皮間葉移行.2010
- Author(s)
  戸川寛子、中西浩一、島友子、佐古まゆみ、向山弘展、宮嶋正康、野津寛大、吉原大輔、長尾静子、飯島一誠、吉川徳茂
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 検定交配における画像診断の有用性2010
- Author(s)
  羽根田千江美、鈴木昇一、家池勤、長尾静子、濱中功、松山睦司
- Organizer
  東海実験動物研究会 7 月例会
- Place of Presentation
  津
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデル Cy ラットにおける嚢胞形成と RXR との関連性についての検討.2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCK ラットの腎臓と肝臓における PPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 検定交配における画像診断の有用性2010
- Author(s)
  羽根田千江美、鈴木昇一、家池勤、長尾静子、濱中功、松山睦司
- Organizer
  東海実験動物研究会7月例会
- Place of Presentation
  津
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒトARPKDと相同遺伝子変異を有するPCK ratにおける上皮間葉移行2010
- Author(s)
  戸川寛子、中西浩一、島友子、佐古まゆみ、向山弘展、宮嶋正康、野津寛大、吉原大輔、長尾静子、飯島一誠、吉川徳茂
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎の治療に向けた最近の研究モデル動物を用いて2010
- Author(s)
  長尾静子
- Organizer
  第5回Sendai Renal Research Seminar
- Place of Presentation
  仙台(招待講演)
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 常染色体劣性多発性嚢胞腎(ARPKD)モデルcpkマウスの尿細管上皮細胞における上皮間葉移行(EMT)2010
- Author(s)
  戸川寛子、中西浩一、島友子、佐古まゆみ、向山、宮嶋正康、野津寛大、吉原大輔、長尾静子、飯島一誠、吉川徳茂
- Organizer
  第45回日本小児腎臓病学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 非侵襲的拒絶反応診断法としてのFDG-PETの有用性の検討2010
- Author(s)
  森田美和、辻厚至、釘田雅則、吉原大輔、李小康、杉岡篤, 長尾静子
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] PCKラットの腎臓と肝臓におけるPPAR-γアゴニストの治療効果2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第18回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2010-10-31
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 嚢胞性腎臓疾患モデルCyラットにおける嚢胞形成とRXRとの関連性についての検討2010
- Author(s)
  釘田雅則、西井一宏、森田美和、吉原大輔、山口太美雄、日下守、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 遺伝性胸腺過形成を示す BUF/Mna 系ラットにおける画像診断の有用性.2010
- Author(s)
  羽根田千江美、鈴木昇一、井田義宏、家池勤、長尾静子、松山睦司
- Organizer
  日本実験動物技術者協会第44回総会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Fluid secretion from the pancreatic duct in PCK rats2010
- Author(s)
  Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S
- Organizer
  Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-21590873
[Presentation] ヒトARPKDとオーソログな遺伝子変異モデルであるPCKラットの腎・肝組織における情報伝達系の検討2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D, Kurahashi H, Morita M, Kugita M, Hiki Y, Aukema HM, Yamaguchi T, Calvet JP, Wallace DP, Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition.
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 非侵襲的拒絶反応診断法としての FDG-PET の有用性の検討.2010
- Author(s)
  森田美和、辻厚至、釘田雅則、吉原大輔、李小康、杉岡篤, 長尾静子
- Organizer
  第57回日本実験動物学会総会.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデルPCKの腎臓と肝臓における細胞情報伝達系の解析2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Fluid secretion from the pancreatic duct in PCK rats.2010
- Author(s)
  Yi L, Ishiguro H, Yamamoto A, Nakakuki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S.
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 常染色体劣性多発性嚢胞腎(ARPKD)モデル cpk マウスの尿細管上皮細胞における上皮間葉移行(EMT).2010
- Author(s)
  戸川寛子、中西浩一、島友子、佐古まゆみ、向山弘展、宮嶋正康、野津寛大、吉原大輔、長尾静子、飯島一誠、吉川徳茂
- Organizer
  第45回日本小児腎臓病学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Thiazolidinedione Ameliorates Autosomal Recessive Polycystic Kidney and Liver Disease in the PCK Rat, an Orthologous Model of Human ARPKD.2010
- Author(s)
  Yoshihara D., Kurahashi H., Morita M., Kugita M., Hiki Y., Aukema H.M., Yamaguchi T., Calvet J.P., Wallace D.P., Nagao S.
- Organizer
  American Society of Nephrology 43rd Annual Meeting & Scientific Exposition
- Place of Presentation
  Denver, CO USA
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎ラットモデル PCK の腎臓と肝臓における細胞情報伝達系の解析.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、山口太美雄、倉橋浩樹、長尾静子
- Organizer
  第42回藤田医学会総会
- Place of Presentation
  豊明
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Fluid secretion from the pancreatic duct in PCK rats.2010
- Author(s)
  Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S.
- Organizer
  Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Fluid secretion from the pancreatic duct in PCK rats.2010
- Author(s)
  Yi L, Ishiguro H, Yamamoto A, Nakauki M, Furuya S, Nagao S, Wei M, Kondo T, Naruse S.
- Organizer
  Joint Meeting of the International Association of Pancreatology and the Japan Pancreas Society.
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 遺伝性胸腺過形成を示すBUF/Mna系ラットにおける画像診断の有用性2010
- Author(s)
  羽根田千江美、鈴木昇一、井田義宏、家池勤、長尾静子、松山睦司
- Organizer
  日本実験動物技術者協会第44回総会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Noninvasive imaging with 18F-FDG in rat liver transplantation.2010
- Author(s)
  Morita M., Tsuji A.B., Takahara S., Nagao S., Sugioka A., Koizumi M., Saga T., Li X.K.
- Organizer
  XXIII international congress of The Transplantation Society Vancouver
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] ヒト ARPKDとオーソログな遺伝子変異モデルである PCK ラットの腎・肝組織における情報伝達系の検討.2010
- Author(s)
  吉原大輔、森田美和、釘田雅則、倉橋浩樹、山口太美雄、長尾静子
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] Li XK Noninvasive imaging with 18F-FDG in rat liver transplantation.2010
- Author(s)
  Morita M, Tsuji AB, Takahara S, Nagao S, Sugioka A, Koizumi M, Saga T
- Organizer
  XXIII international congress of TheTransplantation Society Vancouver.
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22590351
[Presentation] 多発性嚢胞腎の治療に向けた最近の研究モデル動物を用いて.2010
- Author(s)
  長尾静子
- Organizer
  第5回 Sendai Renal Research Seminar
- Place of Presentation
  仙台
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-22590351

1. MASANORI Kugita (50440681)

# of Collaborated Projects: 5 results

# of Collaborated Products: 98 results
2. 高橋和男 (90631391)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. ISHIGURO Hiroshi (90303651)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. YAMAGUCHI Tamio (70536292)

# of Collaborated Projects: 3 results

# of Collaborated Products: 62 results
5. KURAHASHI Hiroki (30243215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
6. YAMAMOTO Akiko (60402385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. KONDO Takaharu (20135388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. YOSHIHARA Daisuke (70454402)

# of Collaborated Projects: 2 results

# of Collaborated Products: 71 results
9. MORITA Miwa (90329699)

# of Collaborated Projects: 2 results

# of Collaborated Products: 36 results
10. FURUYA Sonoko (20096952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. ISHIBASHI MIchio (40107032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. HIGASHIHARA Eiji (00092312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. Yuzawa Yukio (00191479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
14. Saito Kuniaki (80262765)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. Fukasawa Motoaki (70387728)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
16. 吉村文 (90466483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. KO Shigeru (90402578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. YAGYU Shigeru (10200479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HIKI Yoshiyuki (20156566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
20. RII Kou (60321890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SUGIOKA Atsushi (20171150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. NAKAKUKI MIyuki (30578729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. CHIHARA Yoshitomo (40405395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KOJIMA Naoto (90420413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. TAKAHASHI Hisahide (80084606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NARUSE Satoru (50180550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAGAHAMA Masato (50198355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Suzuki Atsushi (90340265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
29. Ikezumi Yohei (70361897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Nakajima Kazuki (10442998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
31. 木村千晴 (70214880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 坪井直毅 (50566958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. 鍋島俊隆 (70076751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
34. 熊谷直憲 (40400329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 山田剛史 (90601922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 山田雅之 (40383773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 山本康子 (00331869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. 白水貴大 (80804608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 高野一輝 (70806075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. NANGAKU Masaomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. YOSHIKAWA Norishige

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. NAKANISHI Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. SHIMA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 斉藤邦明

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
45. 塚本宏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 武田憲彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagao Shizuko 長尾 静子

NAGAO Shizuko 長尾 静子

長尾 静子 ナガオ シズコ

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単一遺伝子疾患の病態悪化に拮抗する遺伝子とその情報伝達経路の解明及び治療法の開発Principal Investigator

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Research on the key factors and signal transduction cascades of the onset of chronic kidney disease (CKD): Application of global omics technologies.Principal Investigator

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Omics analysis applicable to preemptive medicine of chronic kidney disease -focusing on comprehensive analysis of phosphorylated proteins-Principal Investigator

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A novel therapeutic approach for cystic disease:Inhibition of intracellular signal transduction pathways by a nuclear receptor cascadePrincipal Investigator

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Nagao Shizuko 長尾静子

NAGAO Shizuko 長尾静子

長尾静子ナガオシズコ