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EGUCHI Yutaka  恵口 豊

ORCIDConnect your ORCID iD *help
… Alternative Names

恵口 豊  エグチ ユタカ

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Researcher Number 20243206
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 准教授
2007 – 2009: 大阪大学, 医学系研究科, 准教授
1999 – 2004: 大阪大学, 医学系研究科, 助教授
1996 – 1998: Osaka University Medical School, Assocate Professor, 医学部, 助教授
1993 – 1995: 大阪大学, 医学部, 助手
1993: 医学部, 助手
1992: 大阪大学, 医学部・遺伝子学研究部, 助手
Review Section/Research Field
Principal Investigator
細胞死(アポトーシス) / Molecular biology / Tumor therapeutics / Hematology
Except Principal Investigator
Cerebral neurosurgery / Digestive surgery / Molecular biology / 分子遺伝学・分子生理学 / Biological Sciences
Keywords
Principal Investigator
アポトーシス / proteome / プロテオーム / 細胞骨格 / カスパーゼ / ICE / Bcl-x / Bcl-2 / ネクローシス / 神経細胞死 … More / apoptosis / bcl-x / bcl-2 / microsomsport / cytoskeleton / caspase / 小胞輸送 / Cytoskeleton / Caspase / Apoptosis / カスバーゼ / アクチン / アミノ酸アミダイト / C型肝炎ウイルス / miR-122 / miR-21 / miR-16 / 核酸医薬 / miRNA / iMIR / ATP / ミトコンドリア / トランスジェニックマウス / 免疫 / 活性酸素 / 小脳顆粒細胞 / cell death / hypoxia … More
Except Principal Investigator
アポトーシス / bcl-2 / apoptosis / プログラム細胞死 / ミトコンドリア / bcl-2遺伝子 / Bcl-2 / リンパ腫 / NL1 / Tet-on system / HVJ-E / gene therapy / doxycycline / tetracycline / Tet-On system / xenograft / ex vivo gene therapy / polymer capsule / pain / mitochondria / ICE / Ran / importin / 染色体転座 / がん遺伝子 / bcl-2がん遺伝子 / PCR / FISH / 染色体異常 / 遺伝子機能 / 転座関連遺伝子 / 造血器腫瘍 / Gene therapy / Liposome / HGF / Brain protection / Gene Therapy / Yama) / caspase-3(CPP32 / cpp32 / yama / cpp32) / caspase-3(yama / beta-endorphin / 異種細胞 / ポリマーカプセル / テトラサイクリン / オピエ-ト / Pain / β-endorphin / caspase / Bc1-2 / Intracellular signal transducction / Cell nucleus / Apoptosis / mRNA export / Nuclear protein transport / Nucleocytoplasmic transport / 画像解析 / 転写因子複合体 / mRNA輸送 / 核膜孔 / 核膜孔ターゲティング複合体 / RNA輸送 / 細胞内情報伝達 / 細胞核 / mRAN輸送 / 核蛋白質輸送 / 核-細胞質間物質輸送 / lymphoma / bcl-2 oncogene / アボトーシス / neuronal cells / knockout mouse / reactive oxygens / transgenic mouse / programd cell death / bcl-2 protooncogene / 神経細胞死 / βリンパ腫 / プログラム死 / ノックアウトマウス / 活性酸素 / 神経細胞 / トランスジェニックマウス / 虚血 / 細胞交代 / 個体発生 / マウス / 形態形成 / オートファジー / ネクローシス / 細胞死 / Acinus / DNA傷害 / シトクロムc / カスペース / 核 / central nervous system / lac2 / HVJ liposome / liposome / GCL6遺伝子 / MLL遺伝子 / BCL2遺伝子 / AML1遺伝子 Less
  • Research Projects

    (22 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (37 People)
  •  Inhibition of microRNA functions by novel nucleic acids, iMIRPrincipal Investigator

    • Principal Investigator
      EGUCHI Yutaka
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Osaka University
  •  Integrated study of cell death: Biology focusing on multiple mechanisms of mammalian cell death

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      2007 – 2012
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Osaka University
  •  Brain protection and recirculation therapy with non-viral vector gene

    • Principal Investigator
      SAITOH Youichi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University
  •  Study on Active Blebbing in ApoptosisPrincipal Investigator

    • Principal Investigator
      EGUCHI Yutaka
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      細胞死(アポトーシス)
    • Research Institution
      Osaka University
  •  アポトーシスにおける細胞質から核への情報伝達メカニズム

    • Principal Investigator
      辻本 賀英
    • Project Period (FY)
      1999 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Study on Active Blebbing in ApoptosisPrincipal Investigator

    • Principal Investigator
      EGUCHI Yutaka
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  Bc1−2遺伝子の髄液内導入による脳保護療法

    • Principal Investigator
      SAITOH Youichi (齋藤 洋一)
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University
  •  Study of molecular basis of apoptosis using in vitro system

    • Principal Investigator
      TSUJIMONOTO Yoshihide
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  Pain treatment with xenogeneic cells transfected with drug inducible opiate gene

    • Principal Investigator
      SAITOH Youichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Osaka University
  •  Novel cancer gene therapy using apoptosis-related gene

    • Principal Investigator
      SHIMIZU Shigeomi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Osaka University
  •  中枢神経系のおけるbcl-2及びbcl-x遺伝子の機能の解析Principal Investigator

    • Principal Investigator
      恵口 豊
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  STUDY OF APOPTOSIS IN VITRO CELL-FREE SYSTEM

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University Medical School
  •  中枢神経系の発生におけるbcl-2遺伝子の機能の解析Principal Investigator

    • Principal Investigator
      恵口 豊
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  免疫細胞の正の選択におけるbcl-2関連遺伝子bcl-xの機能の解析Principal Investigator

    • Principal Investigator
      恵口 豊
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Hematology
    • Research Institution
      Osaka University
  •  Molecular communication between the nucleus and cytoplasm

    • Principal Investigator
      YONEDA Yoshihiro
    • Project Period (FY)
      1995 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  中枢神経系の発生におけるbcl-2遺伝子の機能の解析Principal Investigator

    • Principal Investigator
      恵口 豊
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  造血器腫瘍における転座関連遺伝子の機能とその臨床応用

    • Principal Investigator
      鎌田 七男
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hiroshima University
  •  造血器腫瘍における転座関連遺伝子の機能とその臨床応用

    • Principal Investigator
      鎌田 七男
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hiroshima University
  •  ヒトbcl-2がん遺伝子の生理機能の解析

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  中枢神経系の発生におけるbcl-2遺伝子の機能の解析

    • Principal Investigator
      辻本 賀英
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Analysis of oncogenesis involving bcl-2 gene

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University Medical School
  •  Study of bcl-2 function in neuronal cells

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Osaka University

All 2015 2014 2011 2010 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Control of HCV Replication with iMIRs, a Novel Anti-RNAi Agent2015

    • Author(s)
      Saori Itami, Yutaka Eguchi, Takayuki Mizutani, Eriko Aoki, Tadaaki Ohgi, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Hiroshi I Suzuki, Norifumi Kawada and Yoshiki Murakami
    • Journal Title

      Molecular Therapy Nucleic Acids

      Volume: 4 Pages: e219-e219

    • DOI

      10.1038/mtna.2014.71

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25640090, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-25293110
  • [Journal Article] Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mnd2 mutant mice.2010

    • Author(s)
      Ideguchi, K., Shimizu, S., Okumura, M. and Tsujimoto, Y.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 393 Pages: 264-267

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Screening of cell death genes with a mammalian genome-wide RNAi library.2010

    • Author(s)
      Tsujii, H., Eguchi, Y., Chenchik, A., Mizutani, T., Yamada, K., and Tsujimoto, Y.
    • Journal Title

      J. Biochem.

      Volume: 148 Pages: 157-170

    • NAID

      10027877516

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] A novel mechanism for conecting bacterial two-component signal-transduction systems2005

    • Author(s)
      Eguchi Yutaka
    • Journal Title

      Trends Biochem Sci 30

      Pages: 70-72

    • Data Source
      KAKENHI-PROJECT-14370432
  • [Journal Article] Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two component systems of Escherichia coli2004

    • Author(s)
      Eguchi Yutaka
    • Journal Title

      J Bacteriol 186

      Pages: 347-356

    • Data Source
      KAKENHI-PROJECT-14370432
  • [Journal Article] Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mdn2 mutant mice

    • Author(s)
      Ideguchi, K.
    • Journal Title

      Biochem.Biophys.Res.Commun. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] Novel RNAi agent can control HCV replication2014

    • Author(s)
      Yoshiki Murakami, Saori Itami, Takayuki Mizutani, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Yutaka Eguchi, Hiroshi Suzuki
    • Organizer
      Keystone Symposia, “RNA Silencing”
    • Place of Presentation
      Seattle, Washington USA
    • Data Source
      KAKENHI-PROJECT-25640090
  • [Presentation] Necrostatin-1とDiindolyl-methaneで抑制される新規タイプのネクローシス2011

    • Author(s)
      恵口豊、辻本賀英
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] Necrostatin-1とDiindolyl-methaneで抑制される新規タイプのネクローシス2011

    • Author(s)
      恵口豊、辻本賀英
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] miR-122 に対するiMIR はC 型肝炎ウイルス複製抑制に効果的である

    • Author(s)
      伊丹沙織、村上善基、黒田雅彦、落谷孝広、恵口豊、河田則文
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25640090
  • 1.  TSUJIMOTO Yoshihide (70132735)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 2.  EGUCHI Yutaka (20243214)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  SHIMIZU Shigeomi (70271020)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SAITOH Youichi (20252661)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  ARITA Norio (80159508)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  鎌田 七男 (00034629)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  林 泰秀 (30238133)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  瀬戸 加大 (80154665)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  垣塚 彰 (80204329)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  大木 操 (00158792)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  LAZEBNIK Yuri
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  SHINZAWA Koei (70403186)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SHIBUYA Toshiharu (70448033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HAMADA Yoshio (10132739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MURAKAMI Yoshiki (00397556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 16.  SUZUKI Hiroshi (00587793)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  OCHIYA Takahiro (60192530)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 18.  KURODA Masahiko (80251304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 19.  YONEDA Yoshihiro (80191667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  FUJII Takashi (10156870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  OHSHIMA Yasumi (90037606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ADACHI Yoshifumi (50201893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HAYAKAWA Toru (20135700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KATO Amami (00233776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YOSHIMINE Toshiki (00201046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  大野 陸人 (80201979)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  上池 渉 (40152847)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  小川 智 (90283746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KATSUMATA Makoto
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  EWERT Donald
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SEKIGUCHI Takeshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  WATAHIKI Masanori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  DONALD Ewert
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  東 義明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  益子 信郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  鎌田 振吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 37.  辻本 貨英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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