HATORI Masashi 羽鳥仁志

Researcher Number	20245814
External Links
Affiliation (based on the past Project Information) *help	2007 – 2010: Showa University, Dept Oral Maxillofac Surg., Associate Professor 1999 – 2006: 昭和大学, 歯学部, 講師 2000: 昭和大, 歯学部, 助手 1996 – 1999: 昭和大学, 歯学部, 助手 1995: 昭和大学, 歯学部・第二口腔外科学教室, 助手
Review Section/Research Field	Principal Investigator Surgical dentistry / Surgical dentistry Except Principal Investigator Surgical dentistry / Surgical dentistry
Keywords	Principal Investigator MMP / HIF / c-Met / HGF / VEGFR-3 / 口腔扁平上皮癌 / RT-PCR / 扁平上皮癌 / フローサイトメトリー / INVASIVENESS … More / CELL CYCLE / OSCC / HYPOXIA / 線維芽細胞 / 増殖能 / 浸潤能 / SQUAMOUS CELL CARCINOMA / LYMPHANGIOGENESIS / VFGF / HIF-1α / 遺伝子導入 / HIF1-α / SCC抗原 / VEGF / ウイルス治療 / TGF-beta / Smad7 / テロメラーゼ / 口腔癌関連遺伝子 / DNAマイクロアレイ / Gene Chip / IMS / LCM / western blot / p53 / MDM2 / ARF / nested PCR / サイトケラチン19 / E-カドヘリン / CD44 / 磁気ビーズ / SNAP / セレクチン / ヒト口腔扁平上皮癌細胞NA / 一酸化窒素 / 血管内皮細胞 / northern blot法 / C-myc / 断片化DNA / アガロース電気泳動 / 5-FU / CBDCA / NA細胞 / アポトーシス … More Except Principal Investigator 口腔癌 / p21 / 4NQO / MMP / CD44 / PT-PCR / mRNA / ATM / MDM2 / DEXA / サイトカイン / 遺伝子導入 / アポトーシス / Cytokeratin 19 / circulating cancer cell / magnetic bead / metastasis / oral cancer / RT-PCR / 末梢血中細胞 / 局平上皮癌 / サイトケラチン19 / 末稍血中癌細胞 / 磁気ビーズ / 転移 / p53 gene deficient mouse / CDK inhibitors / carcinogenesis / oral leukoplakia / P53遺伝子欠失マウス / P21 / DNA-PK / p53遺伝子欠失マウス / CDK阻害因子 / 癌化 / 白板症 / cytokine / Invasion, metastasis / mouse / B 16 melanoma / Oral Cancer / INF-r / アデイウイルスベクター / B16メラノーマ細胞 / 浸潤・転移 / マウス / B16メラノーマ / インターフェロン-γ / japanease white rabbit / mandible / low bone mineral density / fracture / 骨密度 / 非脱灰研磨切片 / 日本白色家兎 / 下顎骨 / 低骨塩 / 骨折 / CELL DEATH / ARTICULAR CHONDROCYTE / CYTOKINE / MECHANICAL STRESS / OSTEOPOROSUS / 細胞死 / 関節軟骨細胞 / メカニカルストレス / 骨粗鬆症 / デスレセプター / 分子標的治療 / インターフェロン / OK432 / 臨床腫瘍学 / 抗腫瘍効果 / 好中球 / TRAIL / 癌特異抗原 / TGFβ / 樹状細胞療法 / 癌の可視化 / ウィルス性剤 / テロメスキャン / テロメライシン / 口腔扁平上皮癌 / ウイルス治療 / テロメラーゼ / G1期 / c-fos / c-myc / 細胞周期 / 口腔粘膜上皮 / 遺伝子欠失マウス / p53 / Tunel法 / bcl-2 / Fasリガント / Fas抗原 / 浸潤リンパ球 / 口腔扁平苔癬 Less

Antitumor effect of neutrophil-derived TRAIL for oral squamous cell carcinoma
- Principal Investigator
  
  IWASE Masayasu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tsurumi University
  Showa University
テロメラーゼ作動性Smad7発現型ウイルスによる口腔癌の制御Principal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
Telomerase-Specific Replication-Selective Virotherapy for oral squamous cell carcinoma cell lines
- Principal Investigator
  
  SHINTANI Satoru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
TGF阻害と新規癌抗原を組み合わせた強化型口腔癌樹状細胞療法開発のための研究
- Principal Investigator
  
  伊東大典
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
ESTABLISHMENT OF TUMOR SPECIFIC MOLECULER TARGETTING THERAPY AGAINST HYPDXIA INDUCIBLE FACTORPrincipal Investigator
- Principal Investigator
  
  HATORI Masashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
ESTABLISHMENT OF ANTI-LYMPHANGIOGENETIC THERAPY BY CANCER SPECIFIC s-VEGFR-3.Principal Investigator
- Principal Investigator
  
  HATORI Masashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  SHOWA UNIVERSITY
DNAマイクロアレイとLCM法を用いた口腔癌関連遺伝子データベースの構築Principal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
組織特異的p19ARF遺伝子導入による口腔癌治療法の開発Principal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
The effects of CDK inhibitors and PI3 kinase related kinase on the carcinogenesis from precancerous lesions
- Principal Investigator
  
  NAGUMO Masao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
Development of detection method of metastasis from squamous cell carcinoma of head and neck using peripheral blood
- Principal Investigator
  
  NAGUMO Masao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
頭頚部扁平上皮癌症例における末梢血中微小癌細胞検出法の開発Principal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
THE ESTABLISHMENT OF ORAL CANCER THERAPY USING TISSUE SPECIFIC INF-r GENE
- Principal Investigator
  
  YAGAMI Kimitoshi, 上條竜太郎
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
p53遺伝子欠失マウスを用いた口腔癌発症機序の解析
- Principal Investigator
  
  南雲正男
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
The influence of low bone mineral density on the fracture healing
- Principal Investigator
  
  MANABE Masato
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
血管内皮細胞の産生する一酸化窒素による癌転移の制御機構Principal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
口腔扁平苔癬における粘膜下リンパ球浸潤の維持機構
- Principal Investigator
  
  NAGUMO Masao
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
Effects of mechanical stress and cytokines on articular chondrocytes from osteoporosis animals
- Principal Investigator
  
  KAKUTA Saburo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
口腔扁平上皮癌における抗癌剤の効果とアポトーシスPrincipal Investigator
- Principal Investigator
  
  羽鳥仁志
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University

All 2009 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Enhanced susceptibility to apoptosis of oral squamous cell carcinoma cells subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitors2007
- Author(s)
  Iwase, M, Yoshiba, S, Uchida, M, Takaoka, S, Kurihara, Y, Ito, D, Hatori, M, Shintani, S
- Journal Title
  
  Int J Oncol 31
  
  Pages: 1141-1147
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] 選択的COX-2阻害はMMP-9の発現低下を介して口腔扁平上皮癌細胞の浸潤能を抑制する.2006
- Author(s)
  齋藤雅子, 羽鳥仁志, 衣笠有里子, 栗原祐史, 伊藤秀寿, 南雲正男
- Journal Title
  
  昭和歯学会雑誌 26
  
  Pages: 1-4
- NAID
  10019605269
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Thalidomide suppresses melanoma growth by activating natural killer cells in mice.2006
- Author(s)
  Kawamata A, Hatori M et al.
- Journal Title
  
  Oncology Report 16
  
  Pages: 1231-1236
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] Thalidomide suppresses melanoma growth by activating natural killer cells in mice2006
- Author(s)
  Kawamata A, Hatori M, et. al.
- Journal Title
  
  Oncology Report 16
  
  Pages: 1231-1236
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] 選択的COX-2阻害はMMP-9の発現低下を介して口腔扁平上皮癌細胞の浸潤能を抑制する2006
- Author(s)
  齋藤雅子, 羽鳥仁志, 衣笠有里子, 栗原祐史, 伊藤秀寿, 南雲正男
- Journal Title
  
  昭和歯学会雑誌 26・1
  
  Pages: 1-4
- NAID
  10019605269
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Thalidomide suppresses melanoma growth by activatiing natural killer cells in mice2006
- Author(s)
  Kawamata, A, Ito, D, Odani, T, Isobe, T, Iwase, M, Hatori, M, Nagumo, M
- Journal Title
  
  Oncology Report 16
  
  Pages: 1231-1236
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] 口腔扁平上皮癌細胞に対するCOX-2阻害療法の基礎的検討2005
- Author(s)
  衣笠有里子, 羽鳥仁志, 伊藤秀寿, 栗原祐史, 南雲正男
- Journal Title
  
  日本口腔組織培養学会誌 14
  
  Pages: 29-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Cyclooxygenase-2 : A potential target in the treatment of oral cancers.2005
- Author(s)
  Hatori M, Nagumo M
- Journal Title
  
  Oral Science International 2
  
  Pages: 1-7
- NAID
  130004503803
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of MMP-2 and CD442005
- Author(s)
  Kinugasa, Y.Hatori, M.et al.
- Journal Title
  
  Clinical and Experimental Metastasis (In press)
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Cyclooxygenase-2: A potential target in the treatment of oral cancers.2005
- Author(s)
  Hatori M, Nagumo M
- Journal Title
  
  Oral Sci Int 2
  
  Pages: 1-7
- NAID
  130004503803
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Cyclooxygenase-2 : A potential target in the treatment of oral cancers.2005
- Author(s)
  Hatori M, Nagumo M
- Journal Title
  
  Oral Sci Int 2
  
  Pages: 1-7
- NAID
  130004503803
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Effect of 5-fluorouracil on G1 phase cell cycle regulation in oral cancer cell lines.2004
- Author(s)
  Li M-H, Ito D, Sanada M, Odani T, Hatori M, Iwase M, Nagumo M
- Journal Title
  
  Oral Oncol. 40
  
  Pages: 63-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulaion of matrix metalloproteinase-2 and CD44.2004
- Author(s)
  Kinugasa Y, Hatori M, Ito H, Kurihara Y, Ito D, Masao Nagumo
- Journal Title
  
  Clin Exp Metastasis 21
  
  Pages: 737-745
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44.2004
- Author(s)
  Kinugasa Y, Hatori M, Ito H, Kurihara Y, Ito D, Masao Nagumo
- Journal Title
  
  Clinical and Experimental Metastasis 21
  
  Pages: 737-745
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Effect of 5-fluorouracil on G1 phase cell cycle regulation in oral cancer cell lines.2004
- Author(s)
  Li M-H, Ito D, Sanada M, Odani T, Hatori M, Iwase M, Nagumo M
- Journal Title
  
  Oral Oncology 40
  
  Pages: 63-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] Enhanced susceptibility to apoptosis of oral squamous cell carcinoma cells subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitors
- Author(s)
  Iwase M, Hatori M, et. al.
- Journal Title
  
  Int J Oncology (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] 頬脂肪体有茎弁移植による口蓋腫瘍切除後の再建:症例報告と文献的考察
- Author(s)
  伊東大典、羽鳥仁志, 他
- Journal Title
  
  Dental Medicine Research (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] Enhanced susceptibility to apoptosis of oral squamous cell carcinoma celis subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitors
- Author(s)
  Iwase M, Hatori M, et. al.
- Journal Title
  
  Int J Oncology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] Thalidomide suppresses melanoma growth by activating natural killer cells in mice.
- Author(s)
  Kawamata A, Odani T, Isobe T, Iwase M, Hatori M, Nagumo M, Ito D
- Journal Title
  
  Journal of immunology (in submission)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Journal Article] 頬脂肪体有茎弁移植による口蓋腫瘍切除後の再建:症例報告と文献的考察
- Author(s)
  伊東大典, 羽鳥仁志, 他
- Journal Title
  
  Dental Medicine Research (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592201
[Journal Article] Thalidomide suppresses melanoma growth by activating natural killer cells in mice.
- Author(s)
  Kawamata A, Odani T, Isobe T, Iwase M, Hatori M, Nagumo M, Ito D
- Journal Title
  
  J Immnol. In submission
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592020
[Presentation] Enhanced susceptibility to TRAIL-mediated apoptosis in oral squamous cell carcinoma cells through down-regulation of cellular FLIP2009
- Author(s)
  MASAYASU IWASE, SAYAKA TAKAOKA, MAKIKO UCHIDA, SAYAKA YOSHIBA, TATSUO SHIROTA, MASASHI HATORI, SATORU SHINTANI
- Organizer
  2nd World Congress of the International Academy of Oral Oncology
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-21592562
[Presentation] 低酸素環壌における口腔扁平上皮癌のHIF-1αの発現及び浸潤能の解析2006
- Author(s)
  栗原祐史, 羽鳥仁志, 他
- Organizer
  第51回日本口腔外科学会総会
- Place of Presentation
  小倉
- Year and Date
  2006-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592201
[Presentation] 低酸素環境における口腔扁平上皮癌のHIF-1αの発現及び浸潤能の解析2006
- Author(s)
  栗原祐史、羽鳥仁志, 他
- Organizer
  第51回日本口腔外科学会総会
- Place of Presentation
  小倉
- Year and Date
  2006-10-12
- Data Source
  KAKENHI-PROJECT-18592201
[Presentation] Effects of hypoxia on cell invasiveness of OSCC cells
- Author(s)
  Yuji, Kuria, Masashi, Hatori, Yuriko, Kinygasa, Masako, Saito, Hidetoshi, Ito, Masaru, Ohaghi, Masao, Nagumo
- Organizer
  The 30th Annual meeting of Japan society for Head andNeck Cancer
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592201

1. NAGUMO Masao (70013993)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. ITO DAISUKE (40286844)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. IWASE Masayasu (50193743)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. SHINTANI Satoru (80294429)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAKUTA Saburo (40112726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MANABE Masato (30190557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAKAMAKI Hideaki (50201520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAGAMI Kimitoshi (00210211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YUI Kumie (50317583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOYOSHIMA Takahiko (90338533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ITO Hidetoshi (80384303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 栗原祐史 (90514969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 河野葉子 (40195681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 上條竜太郎 (70233939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HATORI Masashi 羽鳥 仁志

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

テロメラーゼ作動性Smad7発現型ウイルスによる口腔癌の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ESTABLISHMENT OF TUMOR SPECIFIC MOLECULER TARGETTING THERAPY AGAINST HYPDXIA INDUCIBLE FACTORPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ESTABLISHMENT OF ANTI-LYMPHANGIOGENETIC THERAPY BY CANCER SPECIFIC s-VEGFR-3.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNAマイクロアレイとLCM法を用いた口腔癌関連遺伝子データベースの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

組織特異的p19ARF遺伝子導入による口腔癌治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

頭頚部扁平上皮癌症例における末梢血中微小癌細胞検出法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HATORI Masashi 羽鳥仁志