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NAGUMO Masao
南雲 正男
Connect your ORCID iD
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Researcher Number
70013993
Other IDs
External Links
Affiliation (Current)
2022: 昭和大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information)
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1992 – 2005: 昭和大学, 歯学部, 教授
2000: 昭和大, 歯学部, 教授
1988 – 1990: 昭和大学, 歯学部, 教授
Review Section/Research Field
Principal Investigator
Surgical dentistry
/
Surgical dentistry
/
外科・放射線系歯学
Keywords
Principal Investigator
p21 / 癌化 / アポトーシス / 細胞周期 / 4NQO / oral leukoplakia / MDM2 / Tunel法 / c-myc / 上皮異形成
…
More
/ 口腔白板症 / carcinogenesis / 白板症 / apoptosis / ATM / bcl-2 / p53 / 白血病細胞 / マウス / 発癌剤 / 遺伝子発現プロファイル / 前癌病変 / TGF-alpha / 癌遺伝子 / SNP / P53 / epithelial dysplasia / P21 / P53遺伝子欠失マウス / CDDP / 5-Fu / ICAM-1 / Fas / Fas L / p53遺伝子欠失マウス / mRNA / 口腔癌 / PT-PCR / CD44 / MMP / 舌粘膜上皮 / IFN / TNF / myc mRNA / Ca^<++> influx / 口腔扁平苔癬 / 浸潤リンパ球 / Fas抗原 / Fasリガント / 遺伝子欠失マウス / 口腔粘膜上皮 / c-fos / G1期 / COX-2阻害剤 / NS-398 / 舌癌由来扁平上皮癌細胞 / 増殖抑制 / プロスタグランディン / PD-1遺伝子 / 遺伝子導入 / SCC抗原作動型 / 免疫遺伝子療法 / 口腔癌モデル / マウス舌粘膜 / 4-NQO / 疾患感受性 / ゲノム / 遺伝子多型(SNP) / GeneChipシステム / スクリーニング / サイトカイン / 遺伝子発現 / ランゲルハンス細胞 / 細胞増殖 / ウンゲルハンス細胞 / HLA-DR抗原 / IFN-gamma / ras / myc / precancerous lesions / cytokines / gene expression / Langerhans cell / cell proliferation / Le^Y抗原 / P53蛋白 / TGF-α / Le^y抗原 / 抗癌剤 / 遺伝子 / 異形成 / leukoplakia / Le^y antigen / P53 protein / oncogene / G1サイクリン / サイクリン依存性キナーゼ / Waf1 / TUNEL法 / サイクリン / G1 cycline / cycline dependent kinase / cell cycle / waf1 / p53 knockout mouse / TUNEL method / NO供与体 / カスペース / TNF-α / 5-FU / FasL / 可溶性Fas / IFN-γ / NO donors / caspase / TNF-alpha / CDK阻害因子 / DNA-PK / CDK inhibitors / p53 gene deficient mouse / 転移 / 磁気ビーズ / 末稍血中癌細胞 / サイトケラチン19 / 局平上皮癌 / 末梢血中細胞 / RT-PCR / oral cancer / metastasis / magnetic bead / circulating cancer cell / Cytokeratin 19 / 野生型マウス / 発癌物質 / p53非依存性経路 / Rb / E2F / P53 deficient mouse / wild type mouse / carcinogen / p53 independent pathway / 上皮性異形成 / カリクレイン遺伝子 / サイトケラチン遺伝子 / 癌化予測マーカー / DNAチップ / 免疫染色 / 遺伝子プロファイル / マウス口腔粘膜 / 遺伝子発プロファイル / ヒト白板症 / mouse / gene expression profile / malignant transformation / kallikrein / cytokeratin / marker of malignant transformation / TGFーβ / 白血病細胞の分化 / 相乗効果 / 好中球の活性化 / 分化誘導作用 / 末梢血好中球 / 活性化 / IFNーγ / カルシウムイオン / 好〓球活性化 / 分化誘導 / INF / IL-1 / 好中球 / 活性化の機序 / TGF-beta / Differentiation of Leukemia cell lines / Synergistical effect / Activation of neutrophils
Less
Research Projects
(
14
results)
Co-Researchers
(
10
People)
Project Start Year (Newest)
Project Start Year (Oldest)
SNP解析による口腔白板症の疾患関連遺伝子の同定
Principal Investigator
Principal Investigator
南雲 正男
Project Period (FY)
2005
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Showa University
SCC抗原作動型PD-1-Ig遺伝子を応用した新たな口腔癌免疫遺伝子療法の試み
Principal Investigator
Principal Investigator
南雲 正男
Project Period (FY)
2003 – 2004
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Showa University
Prediction of malignant transformation of oral precancerous lesions by analyzing gene expression profiles and gene polymorphism.
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
2003 – 2005
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Surgical dentistry
Research Institution
Showa University
The participation of p53 independent pathway in the process of oral carcinogenesis
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Showa University
COX-2阻害剤による口腔癌の増殖抑制とその機序の解明
Principal Investigator
Principal Investigator
南雲 正男
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Showa University
The effects of CDK inhibitors and PI3 kinase related kinase on the carcinogenesis from precancerous lesions
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Surgical dentistry
Research Institution
Showa University
Development of detection method of metastasis from squamous cell carcinoma of head and neck using peripheral blood
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Surgical dentistry
Research Institution
Showa University
p53遺伝子欠失マウスを用いた口腔癌発症機序の解析
Principal Investigator
Principal Investigator
南雲 正男
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Showa University
Basic research for oral cancer therapy by anti-cancer drugs and apoptosis-inducing factor
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Showa University
口腔扁平苔癬における粘膜下リンパ球浸潤の維持機構
Principal Investigator
Principal Investigator
南雲 正男
Project Period (FY)
1996
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Showa University
Cell cycle and apoptosis in the process of carcinogenesis in oral precancerous lesions
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Showa University
Apoptosis in the process of carcinogenesis of oral precancerous lesions
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Surgical dentistry
Research Institution
Showa University
Changes of cytokines and their gene expression in the process of carcinogenesis of oral precancerous lesions
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
外科・放射線系歯学
Research Institution
Showa University
Studies of IFN, IL-1, and Tnf on Induction of Differentiation and Activation of Neutrophils.
Principal Investigator
Principal Investigator
NAGUMO Masao
Project Period (FY)
1988 – 1990
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
外科・放射線系歯学
Research Institution
Showa University
# of Projects (Dsc)
# of Projects (Asc)
1.
IWASE Masayasu
(50193743)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
2.
ITO Daisuke
(40286844)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
HATORI Masashi
(20245814)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
KAMIJO Ryutaro
(70233939)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
OSHIMA Osamu
(50167300)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
住谷 要
(70338531)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
YAGAMI Kimitoshi
(00210211)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
YUI Kumie
(50317583)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
KAKUTA Saburo
(40112726)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
桜田 重世
(00112730)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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