• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

NAGUMO Masao  南雲 正男

ORCIDConnect your ORCID iD *help
Researcher Number 70013993
Other IDs
External Links
Affiliation (Current) 2022: 昭和大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help 1992 – 2005: 昭和大学, 歯学部, 教授
2000: 昭和大, 歯学部, 教授
1988 – 1990: 昭和大学, 歯学部, 教授
Review Section/Research Field
Principal Investigator
Surgical dentistry / Surgical dentistry / 外科・放射線系歯学
Keywords
Principal Investigator
p21 / 癌化 / アポトーシス / 細胞周期 / 4NQO / oral leukoplakia / MDM2 / Tunel法 / c-myc / 上皮異形成 … More / 口腔白板症 / carcinogenesis / 白板症 / apoptosis / ATM / bcl-2 / p53 / 白血病細胞 / マウス / 発癌剤 / 遺伝子発現プロファイル / 前癌病変 / TGF-alpha / 癌遺伝子 / SNP / P53 / epithelial dysplasia / P21 / P53遺伝子欠失マウス / CDDP / 5-Fu / ICAM-1 / Fas / Fas L / p53遺伝子欠失マウス / mRNA / 口腔癌 / PT-PCR / CD44 / MMP / 舌粘膜上皮 / IFN / TNF / myc mRNA / Ca^<++> influx / 口腔扁平苔癬 / 浸潤リンパ球 / Fas抗原 / Fasリガント / 遺伝子欠失マウス / 口腔粘膜上皮 / c-fos / G1期 / COX-2阻害剤 / NS-398 / 舌癌由来扁平上皮癌細胞 / 増殖抑制 / プロスタグランディン / PD-1遺伝子 / 遺伝子導入 / SCC抗原作動型 / 免疫遺伝子療法 / 口腔癌モデル / マウス舌粘膜 / 4-NQO / 疾患感受性 / ゲノム / 遺伝子多型(SNP) / GeneChipシステム / スクリーニング / サイトカイン / 遺伝子発現 / ランゲルハンス細胞 / 細胞増殖 / ウンゲルハンス細胞 / HLA-DR抗原 / IFN-gamma / ras / myc / precancerous lesions / cytokines / gene expression / Langerhans cell / cell proliferation / Le^Y抗原 / P53蛋白 / TGF-α / Le^y抗原 / 抗癌剤 / 遺伝子 / 異形成 / leukoplakia / Le^y antigen / P53 protein / oncogene / G1サイクリン / サイクリン依存性キナーゼ / Waf1 / TUNEL法 / サイクリン / G1 cycline / cycline dependent kinase / cell cycle / waf1 / p53 knockout mouse / TUNEL method / NO供与体 / カスペース / TNF-α / 5-FU / FasL / 可溶性Fas / IFN-γ / NO donors / caspase / TNF-alpha / CDK阻害因子 / DNA-PK / CDK inhibitors / p53 gene deficient mouse / 転移 / 磁気ビーズ / 末稍血中癌細胞 / サイトケラチン19 / 局平上皮癌 / 末梢血中細胞 / RT-PCR / oral cancer / metastasis / magnetic bead / circulating cancer cell / Cytokeratin 19 / 野生型マウス / 発癌物質 / p53非依存性経路 / Rb / E2F / P53 deficient mouse / wild type mouse / carcinogen / p53 independent pathway / 上皮性異形成 / カリクレイン遺伝子 / サイトケラチン遺伝子 / 癌化予測マーカー / DNAチップ / 免疫染色 / 遺伝子プロファイル / マウス口腔粘膜 / 遺伝子発プロファイル / ヒト白板症 / mouse / gene expression profile / malignant transformation / kallikrein / cytokeratin / marker of malignant transformation / TGFーβ / 白血病細胞の分化 / 相乗効果 / 好中球の活性化 / 分化誘導作用 / 末梢血好中球 / 活性化 / IFNーγ / カルシウムイオン / 好〓球活性化 / 分化誘導 / INF / IL-1 / 好中球 / 活性化の機序 / TGF-beta / Differentiation of Leukemia cell lines / Synergistical effect / Activation of neutrophils Less
  • Research Projects

    (14 results)
  • Co-Researchers

    (10 People)
  •  SNP解析による口腔白板症の疾患関連遺伝子の同定Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  SCC抗原作動型PD-1-Ig遺伝子を応用した新たな口腔癌免疫遺伝子療法の試みPrincipal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Prediction of malignant transformation of oral precancerous lesions by analyzing gene expression profiles and gene polymorphism.Principal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  The participation of p53 independent pathway in the process of oral carcinogenesisPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  COX-2阻害剤による口腔癌の増殖抑制とその機序の解明Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  The effects of CDK inhibitors and PI3 kinase related kinase on the carcinogenesis from precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Development of detection method of metastasis from squamous cell carcinoma of head and neck using peripheral bloodPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  p53遺伝子欠失マウスを用いた口腔癌発症機序の解析Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Basic research for oral cancer therapy by anti-cancer drugs and apoptosis-inducing factorPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  口腔扁平苔癬における粘膜下リンパ球浸潤の維持機構Principal Investigator

    • Principal Investigator
      南雲 正男
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Cell cycle and apoptosis in the process of carcinogenesis in oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Apoptosis in the process of carcinogenesis of oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Showa University
  •  Changes of cytokines and their gene expression in the process of carcinogenesis of oral precancerous lesionsPrincipal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Showa University
  •  Studies of IFN, IL-1, and Tnf on Induction of Differentiation and Activation of Neutrophils.Principal Investigator

    • Principal Investigator
      NAGUMO Masao
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      外科・放射線系歯学
    • Research Institution
      Showa University
  • 1.  IWASE Masayasu (50193743)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  ITO Daisuke (40286844)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  HATORI Masashi (20245814)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  KAMIJO Ryutaro (70233939)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  OSHIMA Osamu (50167300)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  住谷 要 (70338531)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAGAMI Kimitoshi (00210211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YUI Kumie (50317583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAKUTA Saburo (40112726)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  桜田 重世 (00112730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi