UENO Yoshihito 上野義仁

… Alternative Names

上野義仁ウエノヨシヒト

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Researcher Number	20250467
Other IDs
Affiliation (Current)	2025: 岐阜大学, 応用生物科学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2023: 岐阜大学, 応用生物科学部, 教授 2011 – 2012: 岐阜大学, 応用生物科学部, 准教授 2009 – 2010: Gifu University, 工学部, 准教授 2007: Gifu University, Faculty of Engineering, Associate Professor 2003 – 2006: 岐阜大学, 工学部, 助教授 … More 2001: 岐阜大学, 工学部, 助教授 1998 – 2000: 北海道大学, 大学院・薬学研究科, 助手 1997: 北海道大学, 薬学部, 助手 1994 – 1995: 北海道大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Biological pharmacy / Bioorganic chemistry Except Principal Investigator Drug development chemistry / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Eating habits / General medical chemistry / 医薬分子機能学 / Food science
Keywords	Principal Investigator DNA / 核酸 / 遺伝子 / siRNA / オリゴヌクレオチド / ベンゼン / RNA / ヌクレオチド / ヌクレオシド / 二本鎖核酸 … More / 熱的安定性 / 三本鎖核酸 / gene / microarray / beacon / detection / benzene / Nucleic Acids / ペンゼン / マイクロアレー / ビーコン / 検出 / antigene method / linker / protein / triplex / nucleotide / nucleoside / ゲルシフト / キサントシン / イノシン / 塩基三量体 / 非対称 / 3'-3'結合型 / 三重鎖 / アンチジーン法 / 架橋型核酸 / 核酸結合タンパク / 三重鎖核酸 / 核酸医薬 / 人工核酸 / 塩基識別能 / 二重鎖形成 / 熱力学的安定性 / 熱力的安定性 / RNA二重鎖 / DNA二重鎖 / RNA親和性 / ヌクレアーゼ耐性 / 細胞膜透過性 / アンチセンス核酸 / virus / HCV / oligonucleotide / miRNA / RNAi / 治療 / 肝炎ウイルス / ノックダウン / 抗ウイルス剤 / RNA干渉 / ポリメラーゼ / 水素結合 / DNA合成 / X-線結晶構造解析 / 阻害剤 / 損傷塩基 / 修復酵素 / CD / 分岐型DNA / 固相合成 / ペンタエリスリトール / Tm / 交互配列 / インターカレーター / ホスホロアミダイト法 / エチレンジアミン / 50%融解温度 / ジスルフィド結合 / ピリジルジチオプロピオニル基 / 架橋型オリゴヌクレオチド / DNA鎖切断分子 / ポリアミン … More Except Principal Investigator ソイスタチン / ラクトスタチン / ペプチド / コレステロール / Caco-2細胞 / アルカリフォスファターゼ / IIAEK / FP / 2-5A / アンチセンス核酸 / ペプチドアレイ / 動脈硬化 / 胆汁酸 / ミセル / 核酸医薬 / アルカリホスファターゼ / AlphaFold2 / PPARα / HepG2細胞 / マウス / アルカリ性ホスファターゼ / β-コングリシニン / 脂質ラフト / Caco-2 / 大豆β-コングリシニン / ラット / アプタマー / RNAアプタマー / messenger RNA / oligomer / ribonuclease / 2-5A-antisense / antisense / メッセンジャーRNA / 核酸オリゴマー / リボヌクレアーゼ / 2-5A-アンチセンス / phosphodiester bond / thermal stability / oligodeoxyribonucleotide / 4'-branched thymidine / radical cyclization / antisense molecule / endo-nuclease / exo-nuclease / RNaseH / ラジカル反応 / マラリア / リン酸ジエステル結合 / 熱的安定性 / RNase H / ヌクレアーゼ抵抗性 / 脂質 / カルシウムシグナル / 胆汁酸輸送担体 / HepG2 / CYP7A1 / オリゴ核酸修飾 / siRNA Less

Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Gifu University
Fundamental study on the lipid lowering peptides derived from food proteins
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  Gifu University
Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology
- Principal Investigator
  
  Nagaoka Satoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Gifu University
Development of the tumor marker detection method by RNA aptamer
- Principal Investigator
  
  FUJIWARA Toshinobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kinki University
  Nagoya City University
Development of artificial aromatic nucleic acid with cell membrane permeabilityPrincipal Investigator
- Principal Investigator
  
  UENO Yoshihito
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Novel modification method of oligonucleotides for siRNA medicine
- Principal Investigator
  
  KITAMURA Yoshiaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Development of potent chemically modified siRNAs that suppress HCV replicationPrincipal Investigator
- Principal Investigator
  
  UENO Yoshihito
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Synthesis and properties of a novel oligonucleotides containing a benzene-phosphate backbonePrincipal Investigator
- Principal Investigator
  
  UENO Yoshihito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Synthesis and properties of artificial nucleic acids utilizing pentaerythritol.Principal Investigator
- Principal Investigator
  
  UENO Yoshihito
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
Development of a new generation of 2-5A-antisense and its property for the regulation of gene expression.
- Principal Investigator
  
  KITADE Yukio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Gifu University
修復酵素AlkAの損傷塩基を含むDNA認識様式の解析Principal Investigator
- Principal Investigator
  
  上野義仁
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu University
  Hokkaido University
Design of Nuclease-resistant Antisense Molecules Based on the X-ray Structures of Some Nucleases
- Principal Investigator
  
  MATSUDA Akira
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  医薬分子機能学
- Research Institution
  Hokkaido University
四方向に分岐した特異な構造を有するオリゴヌクレオチドの合成とその性質Principal Investigator
- Principal Investigator
  
  上野義仁
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Hokkaido University
安定な架橋型三本鎖核酸を合成する新手法の開発Principal Investigator
- Principal Investigator
  
  上野義仁
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
亜鉛(II)-環状ポリアミン錯体を用いたDNA鎖切断分子の開発Principal Investigator
- Principal Investigator
  
  上野義仁
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University

All 2024 2023 2022 2020 2018 2014 2013 2011 2010 2009 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] IIAEK Targets Intestinal Alkaline Phosphatase (IAP) to Improve Cholesterol Metabolism with a Specific Activation of IAP and Downregulation of ABCA1.2020
- Author(s)
  Takeuchi, A., Hisamatsu, K., Okumura, N., Sugimitsu, Y., Yanase, E., Ueno, Y. and Nagaoka, S.
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 9 Pages: 2859-2859
- DOI
  10.3390/nu12092859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00570
[Journal Article] Diazirine-containing RNA photo-crosslinking probes for capturing microRNA targets2014
- Author(s)
  Nakamoto, K. and Ueno, Y.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 79 Pages: 2463-2472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659045
[Journal Article] Synthesis, thermal stability and photochemical properties of DNA containing fluorescent biary-type nucleoside surrogates2013
- Author(s)
  Iwata, M., Ogata, A., Ito, Y. and Ueno, Y.
- Journal Title
  
  J. Chem. Chem. Eng.
  
  Volume: 7 Pages: 962-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659045
[Journal Article] Incorporation of biaryl units into the 5' and 3' ends of sense and antisense strands of siRNA duplexes improves strand selectivity and nuclease resistance2011
- Author(s)
  Yoshikawa, K., Ogata, A., Matsuda, C., Kohara, M., Iba, H., Kitade, Y. and Ueno, Y.
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 22 Issue: 1 Pages: 42-49
- DOI
  10.1021/bc100301w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Biaryl modification of the 5′-terminus of one strand of a microRNA duplex induces strand specificity2010
- Author(s)
  Ogata, A., Furukawa, C., Sakurai, K., Iba, H., Kitade, Y. and Ueno, Y.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 20 Pages: 7299-7302
- URL
  http://dx.doi.org/10.1016/j.bmcl.2010.10.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Diazirine-containing RNA photocrosslinking probes for the study of siRNA-protein interactions2010
- Author(s)
  Kuboe, S., Yoda, M., Ogata, A., Kitade, Y., Tomari, Y. and Ueno, Y.
- Journal Title
  
  ChemCom
  
  Volume: 46 Issue: 39 Pages: 7367-7369
- DOI
  10.1039/c0cc02450c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Effect of incorporation of alkyl linkers into siRNAs on RNA interference2009
- Author(s)
  Ueno, Y., Yoshikawa, K., Kitamura, Y. and Kitade, Y.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 19 Pages: 875-877
- URL
  http://dx.doi.org/10.1016/j.bmcl.2008.11.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Synthesis of nuclease-resistant siRNAs possessing universal overhangs2009
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorg.Med.Chem. 17
  
  Pages: 1974-1981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article]2009
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorg.Med.Chem.Lett. 19
  
  Pages: 875-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Synthesis of nuclease-resistant siRNAs possessing universal overhangs2009
- Author(s)
  Ueno, Y., Watanabe, Y., Shibata, A., Yoshikawa, K., Takano, T., Kohara, M. and Kitade, Y.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 17 Pages: 1974-1981
- URL
  http://dx.doi.org/10.1016/j.bmc.2009.01.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590114
[Journal Article] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2007
- Author(s)
  Y. Ueno, et. al.
- Journal Title
  
  Nucleic Acids Sympo. Ser. 51
  
  Pages: 293-294
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Journal Article] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2007
- Author(s)
  Y. Ueno, et. al.
- Journal Title
  
  Nucleic Acids Sympo. Ser 51
  
  Pages: 293-294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Journal Article] RNAi knockdown of caspase-activated DNase inhibits rotenone-induce DNA fragmentation in HeLa cells2007
- Author(s)
  Y. Ueno, et. al.
- Journal Title
  
  Neurochemistry International 50
  
  Pages: 601-606
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590095
[Journal Article] Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein2006
- Author(s)
  A.Shibata, Y.Ueno, K.Shinbo, M.Nakanishi, A.Matsuda, Y.Kitade
- Journal Title
  
  Bioorg. Med. Chem. Lett. 16
  
  Pages: 1410-1413
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein.2006
- Author(s)
  A.Shibata, Y.Ueno, K.Shinbo, M.Nakanishi, A.Matsuda, Y.Kitade
- Journal Title
  
  Bioorg.Med.Chem.Lett. 16
  
  Pages: 1410-1413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of cross-linked triple helical DNAs possessing high affinity to triple helical DNA binding protein.2005
- Author(s)
  A.Shibata, Y.Ueno, M.Nakanishi, A.Matsuda, Y.Kitade
- Journal Title
  
  Nucleic Acids Sympo.Ser. 49
  
  Pages: 183-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of cross-linked triple helical DNAs possessing high affinity to triple helical DNA binding protein2005
- Author(s)
  A.Shibata, Y.Ueno, M.Nakanishi, A.Matsuda, Y.Kitade
- Journal Title
  
  Nucleic Acids Sympo. Ser. 49
  
  Pages: 183-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of 2',5'-Oligoadenylate Analogs Containing an Adenine Acyclonucleoside and their Ability to activate Human RNase L.2004
- Author(s)
  上野義仁
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 4431-4434
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Thermal stability of triple helical DNAs containing 2'-deoxyinosine and 2'-deoxyxanthosine.2004
- Author(s)
  Y.Ueno, A.Shibata, et al.
- Journal Title
  
  Bioorg.Med.Chem. 12
  
  Pages: 6581-6586
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of 2',5'-Oligoadenylate Analogs Containing an Adenine Acyclonucleoside and their Ability to activate Human RNase L.2004
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters. 14
  
  Pages: 4431-4434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Synthesis of 2',5'-oligoadenylate analogs containing an adenine aycylonucleoside and their ability to activate human RNase L2004
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 14
  
  Pages: 4431-4434
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Alternate-strand triple-helix formation by 3'-3'-linked oligodeoxynucleotides composed of asymmetrical sequences2004
- Author(s)
  S.Hoshika, Y.Ueno, H.Kamiya, A.Matsuda
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14
  
  Pages: 3333-3336
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Alternate-strand triple-helix formation by 3'-3'-limked oligodeoxynucleotides composed of asymmetrical sequences2004
- Author(s)
  S.Hoshika, Y.Ueno et al.
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 3333-3336
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Thermal stability of triple helical DNAs containing 2'-deoxyinosine and 2'-deoxyxanthosine2004
- Author(s)
  Y.Ueno, A.Shibata, A.Matsuda, Y.Kitade
- Journal Title
  
  Bioorg. Med. Chem. 12
  
  Pages: 6581-6586
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Alternate-strand triple-helix formation by 3'-3'-linked oligodeoxynucleotides composed of asymmetrical sequences.2004
- Author(s)
  S.Hoshika, Y.Ueno, H.Kamiya, A.Matsuda
- Journal Title
  
  Bioorg.Med.Chem.Lett. 14
  
  Pages: 3333-3336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Thermal stability of triple helical DNAs containing 2'-deoxyinosine and 2'-deoxyxanthosine.2004
- Author(s)
  Y.Ueno, A.Shibata, A.Matsuda, Y.Kitade
- Journal Title
  
  Bioorg.Med.Chem. 12
  
  Pages: 6581-6586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590082
[Journal Article] Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.2003
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters. 13
  
  Pages: 3959-3961
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.2003
- Author(s)
  上野義仁
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters 13
  
  Pages: 3959-3961
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] A Specific Substrate-inhibitor, a 2'-Deoxy-2'-fluorouridine-containing Oligoribonucleotide, against Human RNase L.2003
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioorganic & Medicinal Chemistry. 11
  
  Pages: 5069-5073
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Synthesis of antisense oligonucleotides carrying modified 2-5A molecules at their 5'-termini and their properties.2003
- Author(s)
  上野義仁
- Journal Title
  
  Bioconjugate Chemistry 14
  
  Pages: 690-696
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] Synthesis of antisense oligonucleotides carrying modified 2-5A molecules at their 5'-termini and their properties.2003
- Author(s)
  Yoshihito Ueno
- Journal Title
  
  Bioconjugate Chemistry. 14
  
  Pages: 690-696
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Journal Article] A Specific Substrate-inhibitor, a 2'-Deoxy-2'-fluorouridine-containing Oligoribonucleotide, against Human RNase L.2003
- Author(s)
  上野義仁
- Journal Title
  
  Bioorganic & Medicinal Chemistry 11
  
  Pages: 5069-5073
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390036
[Presentation] 脂質代謝改善ペンタペプチドIIAEKが誘導するコレステロール吸収抑制には、腸アルカリ性ホスファターゼとの相互作用が必須である2024
- Author(s)
  竹内朝陽、小田夏暉、久松賢太郎、奥村菜月、杉光祐紀、葉宇陽、高田敬梧、森凌輔、會田拓巳、柳瀬笑子、上野義仁、長岡利
- Organizer
  2024年度日本農芸化学会
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] 腸アルカリフォスファターゼはコレステロール（CHOL）低減化ペプチドIIAEKの受容体としてCHOL代謝を改善する2023
- Author(s)
  竹内朝陽, 葉宇陽, 高田敬梧, 小田夏暉，森崚輔, 會田拓巳, 坂野新太, Maihemuti Mijiti, 柳瀬笑子, 上野義仁, 海老原章郎, 長岡利
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] 脂質代謝改善及び長寿に寄与する腸アルカリフォスファターゼと配列特異的な直接的相互作用をするコレステロール代謝改善ペプチド（IIAEK）2022
- Author(s)
  竹内朝陽、久松賢太郎、奥村菜月、杉光祐紀、中野綾音、柳瀬笑子、上野義仁、長岡利
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] Cholesterol-lowering pentapeptide IIAEK (lactostatin) specifically interacts with intestinal alkaline phosphatase to improve cholesterol metabolism2022
- Author(s)
  Asahi Takeuchi, Kentaro Hisamatsu, Natsuki Okumura, Keigo Takada, Maihemuti Mijiti, Yuyang Ye, Arata Banno, Emiko Yanase, Yoshihito Ueno, Satoshi Nagaoka
- Organizer
  22th IUNS-International Congress of Nutrition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] 脂質代謝改善ペプチド IIAEK（ラクトスタチン）は脂質代謝改善に寄与する腸アルカリフォスファターゼを特異的に活性化する2020
- Author(s)
  竹内朝陽, 奥村菜月, 田口雄規, 杉光祐紀, 久松賢太郎, 柳瀬笑子, 上野義仁, 長岡利
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H00570
[Presentation] 光親和性標識による脂質ラフトにおけるラクトスタチン受容体探索.2018
- Author(s)
  奥村菜月、田口雄規、杉光祐紀、酒井優治、久松賢太郎、上野義仁、長岡利
- Organizer
  2018年度酪農科学シンポジウム（市川）
- Data Source
  KAKENHI-PROJECT-17H00817
[Presentation] 5'-末端にインターカレーターを導入した機能性siRNAの合成と遺伝子発現抑制効果2011
- Author(s)
  上野義仁
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム
- Place of Presentation
  大阪大学コンベンションセンター
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] 芳香族化合物で修飾した安定で有用なRNA分子の開発2010
- Author(s)
  上野義仁
- Organizer
  日本化学会第90春季年会
- Place of Presentation
  東大阪市
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] EFFECT OF INCORPORATION OF AROMATIC COMPOUNDS INTO DANGLING ENDS OF SIRNAS2009
- Author(s)
  K. Yoshikawa, Y. Kitamura, Y. Ueno, and Y. Kitade
- Organizer
  Joint Symposium of the 5th Annual Meeting of the Oligonucleotide Therapeutics Society and 19th Antisense Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] SYNTHESIS OF 5'-CAPPED SIRNA FOR SUPPRESSION OF OFF-TARGET EFFECTS AND ITS CAPABILITY TO ACHIEVE PROTEIN EXPRESSION2009
- Author(s)
  A. Ogata, Y. Ueno, C. Furukawa, K. Sakurai, H. Iba, Y. Kitamura, and Y. Kitade
- Organizer
  Joint Symposium of the 5th Annual Meeting of the Oligonucleotide Therapeutics Society and 19th Antisense Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] SYNTHESIS AND PROPERTIES OF SIRNAS MODIFIED WITH AROMATIC COMPOUNDS2009
- Author(s)
  Y. Ueno
- Organizer
  Joint Symposium of the 5th Annual Meeting of the Oligonucleotide Therapeutics Society and 19th Antisense Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] DIAZIRINE-CONTAINING RNA PHOTO-CROSS-LINKING PROBES FOR THE STUDY OF SIRNA-PROTEIN INTERACTIONS, S. Kuboe2009
- Author(s)
  M. Yoda, Y. Ueno, Y. Tomari, Y. Kitamura, and Y. Kitade
- Organizer
  Joint Symposium of the 5th Annual Meeting of the Oligonucleotide Therapeutics Society and 19th Antisense Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21590114
[Presentation] リン酸アミデート結合を含むsiRNAの合成とその遺伝子発現抑制効果2007
- Author(s)
  上野義仁
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  関西大学
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2007
- Author(s)
  上野義仁
- Organizer
  第34回核酸化学シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] 細胞内タンパク質の核酸結合・分解活性を利用した遺伝子発現抑制会子の開発2007
- Author(s)
  上野義仁
- Organizer
  第18回名古屋コンファレンス
- Place of Presentation
  名古屋大学
- Year and Date
  2007-01-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2007
- Author(s)
  Y. Ueno, et. al.
- Organizer
  34th Nucleic Acids Symposium
- Place of Presentation
  the University of Tokyo
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Development of novel gene-regulating molecules2007
- Author(s)
  Y. Ueno
- Organizer
  Nagoya Conference
- Place of Presentation
  Nagoya University
- Year and Date
  2007-01-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] ベンゼン-リン酸骨格を導入した新規モレキュラー・ビーコンの開発(2)2007
- Author(s)
  上野義仁
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  関西大学
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] ベンゼン-リン酸骨格を導入した新規モレキュラー・ビーコンの開発(1)2007
- Author(s)
  上野義仁
- Organizer
  日本化学会第87春季年会
- Place of Presentation
  関西大学
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone (1)2007
- Author(s)
  Y. Ueno, et. al.
- Organizer
  The Chemical Society of Japan, 87th Annual Meeting
- Place of Presentation
  Kansai University
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone (2)2007
- Author(s)
  Y., Ueno, et. al.
- Organizer
  The Chemical Society of Japan 87th Annual Meeting
- Place of Presentation
  Kansai University
- Year and Date
  2007-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of oligonucleotides containing 5' -amino-2' -fluoro-2',5' -dideoxyuridine2006
- Author(s)
  上野義仁
- Organizer
  第16回アンチセンスシンポジウム
- Place of Presentation
  京都国際会議場
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of novel siRNAs containing hydroPhobic residues at the overhang region2006
- Author(s)
  上野義仁
- Organizer
  第16回アンチセンスシンポジウム
- Place of Presentation
  京都国際会議場
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of oligonucleotides containing 5'-amino-2'-fluoro-2',5'-dideoxyuridine2006
- Author(s)
  Y. Ueno, et. al.
- Organizer
  16th Antisense Symposium
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2006
- Author(s)
  Y. Ueno, et. al.
- Organizer
  16th Antisense Symposium
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of novel siRNAs containing hydrophobic residues at the overhang region2006
- Author(s)
  Y. Ueno, et. al.
- Organizer
  16th Antisense Symposium
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590095
[Presentation] Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at a stem moiety2006
- Author(s)
  上野義仁
- Organizer
  第16回アンチセンスシンポジウム
- Place of Presentation
  京都国際会議場
- Year and Date
  2006-11-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590095

1. Nagaoka Satoshi (50202221)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. 本多裕之 (70209328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KITADE Yukio (20137061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 松井利郎 (20238942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 伊藤弘康 (80373075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOHARA Michinori (10250218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. KITAMURA Yoshiaki (10503659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKEDA Masato (20432867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MATSUDA Akira (90157313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SHUTO Satoshi (70241346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKANISHI Masayuki (00281048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJIWARA Toshinobu (80362804)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 島田昌也 (10576755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 清島満 (10171315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 清水雅仁 (90402198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 出田貴康 (90610379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ITO Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UENO Yoshihito 上野 義仁

上野 義仁 ウエノ ヨシヒト

Research Projects

Research Products

Co-Researchers

Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein

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Fundamental study on the lipid lowering peptides derived from food proteins

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Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology

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Development of the tumor marker detection method by RNA aptamer

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Development of artificial aromatic nucleic acid with cell membrane permeabilityPrincipal Investigator

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Novel modification method of oligonucleotides for siRNA medicine

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Development of potent chemically modified siRNAs that suppress HCV replicationPrincipal Investigator

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Synthesis and properties of a novel oligonucleotides containing a benzene-phosphate backbonePrincipal Investigator

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Synthesis and properties of artificial nucleic acids utilizing pentaerythritol.Principal Investigator

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Development of a new generation of 2-5A-antisense and its property for the regulation of gene expression.

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修復酵素AlkAの損傷塩基を含むDNA認識様式の解析Principal Investigator

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Design of Nuclease-resistant Antisense Molecules Based on the X-ray Structures of Some Nucleases

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四方向に分岐した特異な構造を有するオリゴヌクレオチドの合成とその性質Principal Investigator

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UENO Yoshihito 上野義仁

上野義仁ウエノヨシヒト