Sugawara Minoru 菅原稔

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SUGAWARA Minoru 菅原稔

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Researcher Number	20311558
Affiliation (Current)	2025: 公益財団法人がん研究会, がんプレシジョン医療研究センターがんゲノム医療開発プロジェクト, 研究員
Affiliation (based on the past Project Information) *help	2009: 東北大学, 大学院・医学系研究科, 准教授 2007: 東北大学, 大学院・医学系研究科, 准教授 2006: 国立大学法人東北大学, 医学系研究科, 助教授 2006: 東北大学, 大学院・医学系研究科, 助教授 2005: 東北大学, 医学系研究科, 助教授 1999 – 2004: 東北大学, 大学院・医学系研究科, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Genetics/Genome dynamics Except Principal Investigator Laboratory animal science / Laboratory animal science / Biological Sciences
Keywords	Principal Investigator 癌 / 老化 / ゲノム / 染色体 / 遺伝子 / 修復 / 組み換え / ノックアウトマウス / ジーンターゲティング / ヘリケース … More / Chromosome / Cancer / Aging / Genome / Repair / Recombination / Knockout mouse / Gene Targeting / Helicase / 酵素 … More Except Principal Investigator mouse / PCNA / マウス / モデル動物 / ethyl nitrosourea / induced mutation / gene function / genome function / reverse genetics / mutagenesis / 標的遺伝子変異体 / エチルニトロソウレア / 突然変異誘発 / 遺伝子機能 / ゲノム機能 / 逆遺伝学 / ミュータジェネシス / mutated estrogen receptr / tamoxifen / Cre recombinase / inducible gene targeting / Cre組み換え酵素 / 変異エストロジェンレセプター / タモキシフェン / Cre組換え酵素 / インデューシブル・ジーンターゲティング / シグナル伝達 / シグナル / ゲノム / 癌 / 遺伝子 / 遺伝学 Less

Identification of molecular targets for cancer therapeutics through the analysis of tumor formation in mouse models for human carcinogenesis
- Principal Investigator
  
  NODA Tetsuo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator
- Principal Investigator
  
  菅原稔
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Development of mutant mice carrying base-substitutions in target genes.
- Principal Investigator
  
  GONDO Yoichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  RIKEN
Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator
- Principal Investigator
  
  SUGAWARA Minoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Tohoku University
ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解明Principal Investigator
- Principal Investigator
  
  菅原稔
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator
- Principal Investigator
  
  菅原稔
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator
- Principal Investigator
  
  SUGAWARA Minoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku UniverSity
Development of Inducible Gene Targeting in Mice
- Principal Investigator
  
  TAKANO Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Tohoku University
WRNヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator
- Principal Investigator
  
  菅原稔
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
ヘリケース機能異常による発癌機構の解析Principal Investigator
- Principal Investigator
  
  菅原稔
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator
- Principal Investigator
  
  SUGAWARA Minoru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tohoku University

All 2006 2005 2000 1999

All Journal Article

[Journal Article] The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase2006
- Author(s)
  K.Kumada, Yao, R., Kawaguchi, T., Karasawa, M., Hoshikawa, Y., Ichikawa, K., Sugitani, Y., Imoto, I., Inazawa, J., Sugawara, M., Yanagida, M., Noda, T.
- Journal Title
  
  J. Cell Biol. 172.6
  
  Pages: 835-846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] The selective continued linkage of centromeres through mitosis to interphase in the absence of mammalian separase.2006
- Author(s)
  K.Kumada, R.Yao, T.Kawaguchi, M.Karasawa, Y.Hoshikawa, K.Ichikawa, Y.Sugitani, I.Imoto, J.Inazawa, M.Sugawara, M.Yanagida, T.Noda.
- Journal Title
  
  J.Cell Biol. 172(6)
  
  Pages: 835-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013006
[Journal Article] Altered emotional behavioral responses in mice lacking brain-type fatty acid binding protein gene.2006
- Author(s)
  Y.Owada, Abdelwahab, S.A., Kitanaka, N., Sakagami, H., Takano, H., Sugitani, Y., Sugawara, M., Kawashima, H., Kiso, Y., Mobarakeh, J.I., Yanai, K, Kaneko, K, Sasaki, H., Kato, H., Saino-Saito, S., Matsumoto, N., Akaike, N., Noda, T., Kondo, H.
- Journal Title
  
  European J. Neuroscience 24
  
  Pages: 175-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] 特集「アンチ・エイジングを科学する」、ゲノム維持機構の破綻と遺伝性早老症2005
- Author(s)
  菅原稔
- Journal Title
  
  日本抗加齢医学会雑誌アンチ・エイジング医学 1(2)
  
  Pages: 49-58
- Data Source
  KAKENHI-PROJECT-15200032
[Journal Article] Overexpression of mRNAs of TGFbeta-1 and related genes in fibroblasts of Werner syndrome patients2000
- Author(s)
  Sugawara, M., et. al.
- Journal Title
  
  Mech Ageing Dev. 115(3)
  
  Pages: 189-198
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680669
[Journal Article] Overexpression of mRNAs of TGFbeta-1 and related genes in fibroblasts of Werner syndrome patients.2000
- Author(s)
  Sugawara, M., et
- Journal Title
  
  Mech Ageing Dev. 115(3)
  
  Pages: 189-198
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680669
[Journal Article] Embryonic stem cells.1999
- Author(s)
  Sugawara, M., et. al.
- Journal Title
  
  Blood-Immunity-Cancer. 4(3)
  
  Pages: 92-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680669
[Journal Article] Structures of mouse Rep-8 cDNA and genomic clones1999
- Author(s)
  Sugawara, M., et. al.
- Journal Title
  
  Gene 227(1)
  
  Pages: 39-47
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680669
[Journal Article] Embryonic stem cells1999
- Author(s)
  Sugawara, M., et. al.
- Journal Title
  
  Blood・Immunity・Cancer.(血液・免疫・腫瘍) 4(3)
  
  Pages: 92-102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11680669
[Journal Article] Structures of mouse Rep-8 cDNA and genomic clones.1999
- Author(s)
  Sugawara, M., et. al.
- Journal Title
  
  Gene 227(1)
  
  Pages: 39-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11680669

1. TAKANO Hiroshi (00241555)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. NODA Tetsuo (10183550)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. YAO Ryoji (80291095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. YAGINUMA Katsuyuki (40182307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. GONDO Yoichi (40225678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AIBA Atsu (20271116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. UENO Naoto (40221105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOSEKI Haruhiko (40225446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOMINAMI Ryo (40133615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NISHIDA Keigo (80360618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 阿部訓也 (40240915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山田源 (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sugawara Minoru 菅原 稔

SUGAWARA Minoru 菅原 稔

Research Projects

Research Products

Co-Researchers

Identification of molecular targets for cancer therapeutics through the analysis of tumor formation in mouse models for human carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of mutant mice carrying base-substitutions in target genes.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ウェルナーヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Inducible Gene Targeting in Mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

WRNヘリケース遺伝子ファミリーの機能異常による発癌機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヘリケース機能異常による発癌機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Functional analysis of Werner's helicase family by gene targetingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The selective continued linkage of centromeres from mitosis to interphase in the absence of mammalian separase2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] The selective continued linkage of centromeres through mitosis to interphase in the absence of mammalian separase.2006

Author(s)

Journal Title

Data Source

[Journal Article] Altered emotional behavioral responses in mice lacking brain-type fatty acid binding protein gene.2006

Sugawara Minoru 菅原稔

SUGAWARA Minoru 菅原稔