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nakagami hironori  中神 啓徳

… Alternative Names

NAKAGAMI Hironori  中神 啓徳

中神 啓徳  ナカガミ ヒロノリ

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Researcher Number 20325369
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4494-3601
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 寄附講座教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 寄附講座教授
2016 – 2021: 大阪大学, 医学系研究科, 寄附講座教授
2015: 大阪大学, 医学(系)研究科(研究院), 寄附講座教授
2015: 大阪大学, 医学(系)研究科(研究院), 教授
2015: 大阪大学, 大学院医学系研究科, 寄附講座教授 … More
2014: 大阪大学, 大学院医学系研究科 健康発達医学
2014: 大阪大学, 大学院医学系研究科, 教授
2011 – 2014: 大阪大学, その他の研究科, 教授
2009 – 2014: 大阪大学, 連合小児発達学研究科, 寄附講座教授
2013: 大阪大学, その他の研究科, 寄附講座教授
2013: 大阪大学・金沢大学・浜松医科大学連合, 小児発達学研究科, 教授
2011 – 2012: 大阪大学, その他の研究科, その他
2007 – 2008: Osaka University, Graduate School of Medicine, Assistant Professor
2004 – 2006: 大阪大学, 医学系研究科, 助手
2001: 愛媛大, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 52010:General internal medicine-related / Circulatory organs internal medicine / Medium-sized Section 53:Organ-based internal medicine and related fields / General internal medicine(including psychosomatic medicine) / Cardiovascular medicine / Applied pharmacology / Metabolomics / Circulatory organs internal medicine
Except Principal Investigator
Basic Section 52010:General internal medicine-related / Basic Section 53020:Cardiology-related … More / General internal medicine(including psychosomatic medicine) / Cardiovascular medicine / Basic Section 56010:Neurosurgery-related / Circulatory organs internal medicine / General internal medicine (including Psychosomatic medicine) / Basic Section 56060:Ophthalmology-related / Basic Section 53040:Nephrology-related / Basic Section 56020:Orthopedics-related / Basic Section 54040:Metabolism and endocrinology-related / Orthopaedic surgery / Endocrinology / Metabolomics Less
Keywords
Principal Investigator
ワクチン / 慢性炎症 / 老化細胞 / 抗体 / 高血圧 / パーキンソン病 / アラーミン / 加齢 / 老化 / 糖鎖 … More / 内科 / アンジオテンシン / MRP14 / MDSC / 免疫治療 / 寿命 / 糖尿病 / インスリン抵抗生 / アルファシヌクレイン / インスリン抵抗性 / 糖代謝 / ユビキチン / 動脈硬化 / 認知症 / 血管リモデリング / 脱ユビキチン化酵素 / 低分子G蛋白 / 活性酸素 / 心肥大 / cardiac hypertrophy / NADPH oxidase / Rac1 … More
Except Principal Investigator
ワクチン / 老化 / 炎症 / 動脈硬化 / インスリン抵抗性 / アルツハイマー病 / 認知症 / IL-17A / 循環器・高血圧 / 血管内皮 / 糖尿病 / αシヌクレイン / アンジオテンシンII / 高血圧 / 免疫療法 / タウ / バイオマーカー / 脳梗塞 / 慢性炎症 / 治療ワクチン / 翻訳後修飾 / プロレニン / 糖尿病網膜症 / アンジオテンシン / 強直性脊椎炎 / 脊椎関節炎 / マクロファージ / 酸化ストレス / レニン / eNOS / 軟骨細胞 / レニンーアンジオテンシン系 / 肥満 / 心線維化 / 心不全 / 伝播 / 治療法 / 神経再生 / Toll-like receptor / FAP / BBB / BACE1 / 脳微小血管内皮 / エンドセリン受容体 / エンドセリン / エクソソーム / メタボロミクス解析 / フレイル / トリプトファン / SARS-CoV2 / アンジオテンシン変換酵素2(ACE2) / COVID-19 / ACE2 / アンジオテンシン変換酵素2 / 赤血球 / 骨格筋 / 遺伝子改変ブタ / 若年発症型糖尿病 / 若年発症型成人糖尿病 / 遺伝子改変糖尿病ブタ / オートタキシン / 2型糖尿病 / db/db / MODY3 / ブタ / MODY / 若年発症成人型糖尿病 / ペプチドワクチン / 血栓回収療法 / 脳血管障害 / 部分再開通 / RANKLペプチド / LGR / LGR4 / 血液脳関門 / 神経細胞死 / 糖尿病性腎症 / 糖尿病腎症 / βアレスチン / G蛋白共役型受容体 / 単球 / ケモカイン / レニン-アンジオテンシン系 / アミロイドβ / AGE受容体 / アンジオテンシンII受容体 / 生活習慣病 / 疾患関連遺伝子 / 体軸生脊椎関節炎 / HLA B-27 / ワクチン療法 / HLA B-27 / 療法 / B-27 / HLA / 酸素消費量 / 脂肪分化 / 脂肪炎症 / myoferlin / 免疫 老化 / 癌 / 糖鎖 / 免疫 / 複合糖質ワクチン / 免疫学 / 肺高血圧ラットモデル / ET-1ペプチドワクチン / エンドセリン-1 / エンドセリン-1 / 肺動脈性肺高血圧症 / レニン・アンジオテンシン / IL-17A抗体 / arthritis / 関節炎 / DNAワクチン / リウマチ病学 / 整形外科学 / インフラマソーム / 石灰化 / 血管平滑筋 / 脱ユビキチン化酵素 / CYLD / feeder cell / transplantation / adipokine / 角膜移植 / 血管新生 / アディポサイトカイン / アディポサイエンス / 移植・再生医療 / フィーダー細胞 / 移植医療 / アディポカイン / 血管内皮障害 / ユビキチンシステム / Annexin A1 / 加齢性疾患 / 遺伝子機能スクリーニング / ユビキチン系 / アンジョテンシン受容体拮抗薬 / アンジオテンシン受容体拮抗薬 / 軟骨代謝 / アポトーシス / 軟骨変性 / 軟骨細胞代謝 / 変形性関節症 / アンジオテンシン受容体拮抗剤 / 脂質異常症 / 高血圧症 / NFκB / 細胞老化 / 糖代謝 / メタボリック症候群 / NFkB / 血管内皮機能 / 血圧 / 分子血管病態学 / 老年医学 / 骨折修復 / 骨芽細胞 / ARB / RA系 / アンジオテンシンII受容体拮抗薬 / 骨リモデリング / 骨粗鬆症 / 脂質異常 Less
  • Research Projects

    (40 results)
  • Research Products

    (131 results)
  • Co-Researchers

    (45 People)
  •  Pathophysiological involvement of age-related decline of alpha synuclein expression in brain microvascular endothelium for cognitive impairment

    • Principal Investigator
      鷹見 洋一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  脳梗塞後炎症免疫機構および神経再生におけるFAPの機能解明と治療応用への検討

    • Principal Investigator
      島村 宗尚
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Osaka University
  •  Development of a novel therapy for cardiac fibrosis using a cell removal vaccine

    • Principal Investigator
      勝谷 友宏
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  高齢者のCOVID-19感染リスクを安全に低下し得る新規戦略の開発

    • Principal Investigator
      竹下 ひかり
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Metabolomics analysis of plasma and exosomes for frailty biomarkers

    • Principal Investigator
      横山 世理奈
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  動脈硬化発症プロセスにおける一酸化窒素修飾がもたらすエンドセリン受容体機能の検討

    • Principal Investigator
      林 宏樹
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  認知症関連病的蛋白の翻訳後修飾を標的としたワクチン療法の開発

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Therapeutic vaccine for senolysisPrincipal Investigator

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Pathological involvement of endothelial alpha synuclein in age-related insulin resistance

    • Principal Investigator
      Takami Yoichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  タウ病理の脳内進展過程を標的とした認知症の層別化・個別化治療に向けた基盤的研究

    • Principal Investigator
      武田 朱公
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Development of a novel therapeutic vaccine for diabetic nephropathy

    • Principal Investigator
      Katsuya Tomohiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  Pathophysiological analysis and development of therapy in partial reperfusion in ischemic stroke

    • Principal Investigator
      Shimamura Munehisa
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Osaka University
  •  Development of vaccine therapy for diabetic retinopathy, and new model of diabetic retinopathy

    • Principal Investigator
      YOKOTA Harumasa
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Nihon University
  •  Regulation of chemokine signaling by post-translational modification of beta-arrestin and relationship with atherosclerosis

    • Principal Investigator
      Hayashi Hiroki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Osaka University
  •  Investigation of vaccines using glycolipid antigens for anti-aging

    • Principal Investigator
      Iwabu Yuka
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Lysosome-related molecule myoferlin on macrophages in adipose inflammation associated with obesity

    • Principal Investigator
      Takami Yoichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      Osaka University
  •  Development of a therapeutic vaccine targeting IL17A for treatment of spondyloarthritis.

    • Principal Investigator
      Tomita Tetsuya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  Impact of bisect glycosylationPrincipal Investigator

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 53:Organ-based internal medicine and related fields
    • Research Institution
      Osaka University
  •  Development of novel immunotherapy for chronic inflammatory diseasesPrincipal Investigator

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Basic research for a new concurrent treatment against lifestyle diseases and Alzehimer disease.

    • Principal Investigator
      Yamamoto Koichi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Vaccine development for renin angiotensin system

    • Principal Investigator
      Katsuya Tomohiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Osaka University
  •  Development of vaccine therapy for pulmonary arterial hypertension

    • Principal Investigator
      Ogihara Yoshito
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Mie University
  •  Functional analysis of macrophage CYLD in age-related atherogenesis

    • Principal Investigator
      Takami Yoichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  The prophylactic effect of IL-17A DNA vaccine on arthritis

    • Principal Investigator
      tomita tetsuya
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Osaka University
  •  Development of novel immunotherapy for chronic inflammation by MDSCPrincipal Investigator

    • Principal Investigator
      Nakagami Hironori
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Osaka University
  •  Translational research of therapeutic vaccine to improve the quality of anti-hypertensive therapyPrincipal Investigator

    • Principal Investigator
      Hironori Nakagami
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Angiotensin II Modulates Hypertrophic Differentiation and Apoptosis of Chondrocytes: Relationship of hypertension to Osteoarthrosis

    • Principal Investigator
      Aoki Motokuni
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Morinomiya University of Medical Sciences
  •  Evaluation of hypertension vaccine using pig modelPrincipal Investigator

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Applied pharmacology
    • Research Institution
      Osaka University
  •  Functional screening for novel molecules related to endothelial dysfunction in the ubiquitin system and the potential of their clinical application.

    • Principal Investigator
      Hiromi Rakugi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  The development of hypertension vaccine toward clinical application.

    • Principal Investigator
      Katsuya Tomohiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Osaka University
  •  DNA vaccine for diabetes and dyslipidemia

    • Principal Investigator
      MORISHITA Ryuichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  Analysis for novel function of alpha-synuclein in the endothelium and its clinical significance

    • Principal Investigator
      TAKAMI Yoichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Role of RAS in bone remodeling and protective effect of ARB on bone density

    • Principal Investigator
      AOKI Motokuni
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Morinomiya University of Medical Sciences
  •  Development of DNA vaccine for Angiotensin II

    • Principal Investigator
      KATSUYA Tomohiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Analysis of novel molecule in aging and metabolism toward translational researchPrincipal Investigator

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  Analysis of regulatory molecule on vascular aging

    • Principal Investigator
      KATSUYA Tomohiro
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Novel therapeutic conceot of dementia through vascular axisPrincipal Investigator

    • Principal Investigator
      NAKAGAMI Hironori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Novel Regeneration System based on Fat Producing Adipokine

    • Principal Investigator
      MAEDA Kazuhisa
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Osaka University
  •  心筋特異的誘導型過剰発現マウスの作成によるRaclの心肥大および心不全への関与Principal Investigator

    • Principal Investigator
      中神 啓徳
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  増殖因子による血管新生療法の制御因子としてのホスファターゼの機能解析Principal Investigator

    • Principal Investigator
      中神 啓徳
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Ehime University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

  • [Book] 「高血圧のワクチン療法」血圧(特集:炎症・免疫と高血圧)2013

    • Author(s)
      中神 啓徳
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Book] 「高血圧ワクチンの開発」高血圧診療のすべて2013

    • Author(s)
      中神 啓徳
    • Publisher
      日本医師会雑誌
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Book] Dyslipidemia - From Prevention to Treatment, Chapter 7, Functions of OSBP/ORP Family Proteins and Their Relation to Dyslipidemia

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Development of a Novel and Simple Anti-Metastatic Cancer Treatment Targeting Vasohibin-22023

    • Author(s)
      178.Lee ES, Suzuki Y, Tomioka H, Nakagami H, Sato Y
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 261 Issue: 3 Pages: 239-247

    • DOI

      10.1620/tjem.2023.J076

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Journal Article] Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine2023

    • Author(s)
      Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Miyata Keishi、Torigoe Daisuke、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
    • Journal Title

      npj Vaccines

      Volume: 8 Issue: 1 Pages: 168-168

    • DOI

      10.1038/s41541-023-00770-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21H02827
  • [Journal Article] A novel soluble epoxide hydrolase vaccine protects murine cardiac muscle against myocardial infarction.2022

    • Author(s)
      Kitsuka T, Shiraki A, Oyama JI, Nakagami H, Tanaka A, Node K.
    • Journal Title

      Sci Rep.

      Volume: 12 Issue: 1 Pages: 6923-6923

    • DOI

      10.1038/s41598-022-10641-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Journal Article] Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes2022

    • Author(s)
      Yokota Harumasa、Hayashi Hiroki、Hanaguri Junya、Yamagami Satoru、Kushiyama Akifumi、Nakagami Hironori、Nagaoka Taiji
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 1 Pages: e0262568-e0262568

    • DOI

      10.1371/journal.pone.0262568

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K09835
  • [Journal Article] Novel pathophysiological roles of α‐synuclein in age‐related vascular endothelial dysfunction2022

    • Author(s)
      Takami Yoichi、Wang Cheng、Nakagami Hironori、Yamamoto Koichi、Nozato Yoichi、Imaizumi Yuki、Nagasawa Motonori、Takeshita Hikari、Nakajima Tsuneo、Takeda Shuko、Takeya Yasushi、Kaneda Yasufumi、Rakugi Hiromi
    • Journal Title

      The FASEB Journal

      Volume: 36 Issue: 10

    • DOI

      10.1096/fj.202101621r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07389, KAKENHI-PROJECT-23K21405
  • [Journal Article] RAGE ligands stimulate angiotensin II type I receptor (AT1) via RAGE/AT1 complex on the cell membrane2021

    • Author(s)
      Yokoyama Serina、Kawai Tatsuo、Yamamoto Koichi、Yibin Huang、Yamamoto Hiroko、Kakino Akemi、Takeshita Hikari、Nozato Yoichi、Fujimoto Taku、Hongyo Kazuhiro、Takahashi Toshimasa、Nakagami Futoshi、Akasaka Hiroshi、Takami Yoichi、Takeya Yasushi、Sugimoto Ken、Sawamura Tatsuya、Rakugi Hiromi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 5759-5759

    • DOI

      10.1038/s41598-021-85312-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02732
  • [Journal Article] Cellular senescence and senescence-associated T cells as a potential therapeutic target.2020

    • Author(s)
      Nakagami H
    • Journal Title

      Geriatr Gerontol Int.

      Volume: 20(2) Issue: 2 Pages: 97-100

    • DOI

      10.1111/ggi.13851

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19544, KAKENHI-PROJECT-18H02730
  • [Journal Article] Novel properties of myoferlin in glucose metabolism via pathways involving modulation of adipose functions2020

    • Author(s)
      Nozato Y, Takami Y, Yamamoto K, Nagasawa M, Nozato S, Imaizumi Y, Takeshita H, Wang C, Ito Y, Takeda S, Takeya Y, Sugimoto K, Nakagami H, Hanayama R, Rakugi H.
    • Journal Title

      FASEB J.

      Volume: 34 Issue: 2 Pages: 2792-2811

    • DOI

      10.1096/fj.201901539rr

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08476, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-19H03433
  • [Journal Article] The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice2020

    • Author(s)
      Yoshida S, Nakagami H, Hayashi H, Ikeda Y, Sun J, Tenma A, Tomioka H, Kawano T, Shimamura M, Morishita R, Rakugi H.
    • Journal Title

      Nat Commun

      Volume: 11(1) Issue: 1 Pages: 2482-2482

    • DOI

      10.1038/s41467-020-16347-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02730
  • [Journal Article] Therapeutic Vaccine Against S100A9 (S100 Calcium-Binding Protein A9) Inhibits Thrombosis Without Increasing the Risk of Bleeding in Ischemic Stroke in Mice2018

    • Author(s)
      Kawano T, Shimamura M, Nakagami H, Iso T, Koriyama H, Takeda S, Baba K, Sasaki T, Sakaguchi M, Morishita R, Mochizuki H.
    • Journal Title

      Hypertension

      Volume: 72(6) Issue: 6 Pages: 1355-1364

    • DOI

      10.1161/hypertensionaha.118.11316

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09568, KAKENHI-PROJECT-18H02730
  • [Journal Article] Angiotensin II Peptide Vaccine Protects Ischemic Brain through Reducing Oxidative Stress.2017

    • Author(s)
      1.Wakayama K, Shimamura M, Suzuki J, Watanabe R, Koriyama H, Nakagami H, Mochizuki H, Isobe M, Morishita R.
    • Journal Title

      Stroke

      Volume: 48 Pages: 1362-1368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Journal Article] A peptide vaccine targeting angiotensin II attenuates the cardiac dysfunction induced by myocardial infarction.2017

    • Author(s)
      Watanabe R, Suzuki JI, Wakayama K, Maejima Y, Shimamura M, Koriyama H, Nakagami H, Kumagai H, Ikeda Y, Akazawa H, Morishita R, Komuro I, Isobe M.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 43920-43920

    • DOI

      10.1038/srep43920

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04817, KAKENHI-PROJECT-26460333, KAKENHI-PROJECT-17K08585, KAKENHI-PROJECT-17K19673, KAKENHI-PROJECT-15H04803, KAKENHI-PROJECT-15H04806, KAKENHI-PROJECT-16K15199
  • [Journal Article] Design of Therapeutic Vaccines as a Novel Antibody Therapy For Cardiovascular Diseases.2017

    • Author(s)
      Hironori Nakagami
    • Journal Title

      J Cardiol

      Volume: 69 Issue: 3 Pages: 201-205

    • DOI

      10.1016/j.jjcc.2017.01.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Journal Article] herapeutic Vaccines for Hypertension: a New Option for Clinical Practice.2017

    • Author(s)
      Nakagami H, Morishita R.
    • Journal Title

      Curr Hypertens Rep.

      Volume: 20 Pages: 222017-222017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse2015

    • Author(s)
      Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
    • Journal Title

      Hypertension Research

      Volume: 38(6) Issue: 6 Pages: 382-393

    • DOI

      10.1038/hr.2015.18

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460928
  • [Journal Article] Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats2015

    • Author(s)
      Koriyama H, Nakagami H, Nakagami F, Osako MK, Kyutoku M, Shimamura M, Kurinami H, Katsuya T, Rakugi H, Morishita R.
    • Journal Title

      Hypertension

      Volume: 66 Pages: 167-174

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.2015

    • Author(s)
      Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
    • Journal Title

      Hypertension Research

      Volume: 19

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460928
  • [Journal Article] Development of DNA vaccines as an anti-hypertensive therapy or for anti-angiogenesis.2015

    • Author(s)
      Hironori Nakagami, Ryuichi Morishita
    • Journal Title

      Expert Opin Biol Ther.

      Volume: 15 (3) Issue: 3 Pages: 431-436

    • DOI

      10.1517/14712598.2015.1014791

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461127, KAKENHI-PROJECT-15H04803
  • [Journal Article] Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats.2015

    • Author(s)
      Koriyama H, et. al
    • Journal Title

      Hypertension

      Volume: 66 Issue: 1 Pages: 167-174

    • DOI

      10.1161/hypertensionaha.114.04534

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461250, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25461127
  • [Journal Article] Therapeutic vaccine against DPP4 improves glucose metabolism in mice.2014

    • Author(s)
      Pang Z, Nakagami H, Osako MK, Koriyama H, Nakagami F, Tomioka H, Shimamura M, Kurinami H, Takami Y, Morishita R, Rakugi H.
    • Journal Title

      Proc Natl Acad Sci U S A. 2014 ;111(13):E1256-63.

      Volume: 111(13)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25670433
  • [Journal Article] Therapeutic Vaccines for Hypertension and Dyslipidemia2014

    • Author(s)
      Hironori Nakagami, Hiroshi Koriyama, Ryuichi Morishita
    • Journal Title

      Int. Heart J.

      Volume: 55 Issue: 2 Pages: 96-100

    • DOI

      10.1536/ihj.13-383

    • NAID

      130003392081

    • ISSN
      1349-2365, 1349-3299
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Journal Article] Therapeutic vaccines for hypertension and dyslipidemia2014

    • Author(s)
      Nakagami H, Koriyama H, Morishita R.
    • Journal Title

      Int Heart J

      Volume: 55 Pages: 96-100

    • NAID

      130003392081

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670267
  • [Journal Article] Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway2013

    • Author(s)
      Rodriguez-Araujo G, Nakagami H, Hayashi H, Mori M, Shiuchi T, Minokoshi Y, Nakaoka Y, Takami Y, Komuro I, Morishita R, Kaneda Y
    • Journal Title

      Cell Mol Life Sci

      Volume: 70(6) Pages: 1123-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Journal Article] Decrease in Blood Pressure and Regression of Cardiovascular Complications by Angiotensin II Vaccine in Mice.2013

    • Author(s)
      Futoshi Nakagami
    • Journal Title

      PLoS One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659418
  • [Journal Article] Decrease in Blood Pressure and Regression of Cardiovascular Complications by Angiotensin II Vaccine in Mice.2013

    • Author(s)
      Nakagami F, Koriyama H, Nakagami H, Osako MK, Shimamura M, Kyutoku M, Miyake T, Katsuya T, Rakugi H, Morishita R
    • Journal Title

      PLoS One.

      Volume: 8(3)

    • Data Source
      KAKENHI-PROJECT-23659418
  • [Journal Article] Development of novel DNA vaccine for VEGF in murine cancer model.2013

    • Author(s)
      Kyutoku M
    • Journal Title

      Sci Rep.

      Volume: 3 Issue: 1 Pages: 3380-3380

    • DOI

      10.1038/srep03380

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-25670433
  • [Journal Article] Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.2013

    • Author(s)
      93. Rodriguez-Araujo G, Nakagami H, Hayashi H, Mori M, Shiuchi T, Minokoshi Y, Nakaoka Y, Takami Y, Komuro I, Morishita R, Kaneda Y.
    • Journal Title

      Cell Mol Life Sci.

      Volume: 70(6) Pages: 1123-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Journal Article] Alpha-synuclein elicits glucose uptake and utilization in adipocytes through the Gab1/PI3K/Akt transduction pathway.2013

    • Author(s)
      Rodriguez-Araujo G, Nakagami H, Hayashi H, Mori M, Shiuchi T, Minokoshi Y, Nakaoka Y, Takami Y, Komuro I, Morishita R, Kaneda Y
    • Journal Title

      Cell Mol Life Sci

      Volume: 70 Issue: 6 Pages: 1123-1133

    • DOI

      10.1007/s00018-012-1198-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22126005, KAKENHI-PROJECT-23591101, KAKENHI-PROJECT-24659391, KAKENHI-PROJECT-24790756, KAKENHI-PUBLICLY-23126519
  • [Journal Article] Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Sugimoto K, Yamashita H, Takami Y, Maeda S, Kubo M, Takahashi A, Nakamura Y, Ogihara T, Rakugi H, Kaneda Y, Morishita R.
    • Journal Title

      J Atheroscler Thromb

      Volume: 17(10) Pages: 1054-62

    • NAID

      130004845291

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      Hypertension Res.

      Volume: 33 Pages: 511-514

    • NAID

      10026396580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Akasaka H, Saitoh S, Shimamoto K, Ogihara T, Kaneda Y, Morishita R, Rakugi H.
    • Journal Title

      Hypertens Res

      Volume: 33(5) Pages: 511-4

    • NAID

      10026396580

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      J Atheroscler Thromb.

      Volume: 17 Pages: 1054-1062

    • NAID

      130004845291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Potential role of CYLD(Cylindromatosis)as a deubiquitinating enzyme in vascular cells2008

    • Author(s)
      Takami Y, Nakagami H, Morishita R, Katsuya T, Hayashi H, Mori M, Koriyama H, Baba Y, Yasuda O, Rakugi H, Ogihara T, Kaneda Y.
    • Journal Title

      Am J Pathol 172(3)

      Pages: 818-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Journal Article] Potential role of CYLD (Cylindromatosis)as a deubiquitinating enzyme in vascular cells.2008

    • Author(s)
      Takami Y, Nakagami H, et al.
    • Journal Title

      Am J Pathol. 172

      Pages: 818-829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Journal Article] Ubiquitin carboxyl-terminal hydrolae L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kB activation2007

    • Author(s)
      Takami Y, Nakagami H, et. al.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 27(10)

      Pages: 2184-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Journal Article] Ubiquitin carboxyl-terminal hydrolae L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-kB activation2007

    • Author(s)
      Takami Y, Nakagami H, Morishita R, Katsuya T, Cui TX, Ichikawa T, Saito Y, Hayashi H, Kikkuchi Y, Nishikawa T, Baba Y, Yasuda O, Rakugi H, Ogihara T, Kaneda Y.
    • Journal Title

      Arterioscler Thromb Vasc Biol 27(10)

      Pages: 2184-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Journal Article] Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.2006

    • Author(s)
      Nakagami H, et al.
    • Journal Title

      J Atheroscler Thromb. 13

      Pages: 77-81

    • NAID

      10020627442

    • Data Source
      KAKENHI-PROJECT-18591023
  • [Journal Article] Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy.2006

    • Author(s)
      Nakagami H, Maeda K., et. al.
    • Journal Title

      J Atheroscler Thromb. 13(2)

      Pages: 77-81

    • NAID

      10020627442

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591023
  • [Journal Article] Favorable effect of statins beyond lipid lowering2006

    • Author(s)
      Nakagami, H.
    • Journal Title

      Future Lipidology (in press)

    • Data Source
      KAKENHI-PROJECT-16790419
  • [Journal Article] Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy2006

    • Author(s)
      Nakagami, H, Morishita, R, Maeda, K, Kikuchi, Y, Ogihara, T, Kaneda, Y
    • Journal Title

      J Atheroscler Thromb 13(2)

      Pages: 77-81

    • NAID

      10020627442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591023
  • [Journal Article] Endothelial Dysfunction in Hyperglycemia as a Trigger of Atherosclerosis.2005

    • Author(s)
      Nakagami, H.
    • Journal Title

      Current Diabetes Reviews 1

      Pages: 59-63

    • Data Source
      KAKENHI-PROJECT-16790419
  • [Patent] S100A9を標的とする免疫原性組成物2017

    • Inventor(s)
      中神啓徳、島村宗尚他
    • Industrial Property Rights Holder
      中神啓徳、島村宗尚他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-030327
    • Filing Date
      2017-02-21
    • Data Source
      KAKENHI-PROJECT-15K15310
  • [Presentation] 非感染症疾患を標的とした治療ワクチン開発2024

    • Author(s)
      中神啓徳
    • Organizer
      第53回日本心脈管作動物質学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] Therapeutic Vaccine for non-infectious Diseases2024

    • Author(s)
      Hironori Nakagami
    • Organizer
      Seoul National University Hospital Global Excellence Center for Gene and Cell Therapy Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] 生活習慣病を標的疾患とした治療ワクチン開発2023

    • Author(s)
      中神啓徳
    • Organizer
      第28回国際個別化医療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] Development of Therapeutic Vaccine for Hypertension2023

    • Author(s)
      Hironori Nakagami
    • Organizer
      HYPERTENSION SEOUL
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] プロレニンペプチドワクチンの遺伝子改変糖尿病ブタの網膜血管病変に対する効果2023

    • Author(s)
      横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡辺昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-20K09835
  • [Presentation] Novel Therapeutic option for lifestyle disease2023

    • Author(s)
      中神啓徳
    • Organizer
      日本核酸医薬学会第8回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] 生活習慣病・難治性疾患を標的とした新規ワクチン開発2023

    • Author(s)
      中神啓徳
    • Organizer
      第29回日本遺伝子細胞治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] 高血圧を標的とした新規治療法の開発2023

    • Author(s)
      中神啓徳
    • Organizer
      第55回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] 老化細胞除去を目指した免疫治療の可能性2022

    • Author(s)
      中神啓徳
    • Organizer
      第48回日本臓器保存生物医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] Vaccine development based on gene therapy technology2022

    • Author(s)
      Hironori Nakagami
    • Organizer
      International Vascular Biology Meeting 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] プロレニンペプチドワクチンの血清、房水中の抗体価2022

    • Author(s)
      横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡部昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-20K09835
  • [Presentation] 生活習慣病に対する治療ワクチンの開発2022

    • Author(s)
      中神啓徳
    • Organizer
      第54回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] Therapeutic Vaccine for chronic diseases2022

    • Author(s)
      Hironori Nakagami
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] プロレニンペプチドワクチンの血清、房水中の抗体価2022

    • Author(s)
      横田陽匡、林宏樹、高瀬公陽、花栗潤哉、渡辺昌久、大野皓、小熊秀隆、丸山高史、阿部雅紀、櫛山暁史、中神啓徳、山上聡、長岡泰司
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-20K09835
  • [Presentation] 老化細胞制御による探索的治療への挑戦2021

    • Author(s)
      中神啓徳
    • Organizer
      第21回日本抗加齢医学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] 老化細胞除去治療の実用化に向けて2021

    • Author(s)
      中神啓徳
    • Organizer
      第63回日本老年医学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02827
  • [Presentation] Development of therapeutic vaccine for chronic diseases2020

    • Author(s)
      Hironori Nakagami
    • Organizer
      Korean Society for Molecular and Cellular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02730
  • [Presentation] 強直性脊椎炎に対する抗体産生誘導型ワクチンの開発2020

    • Author(s)
      冨田哲也、孫嬌、柳田結花、林宏樹、森下竜一、中神啓徳
    • Organizer
      第41回日本炎症・再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K09103
  • [Presentation] Inflammation-associated NO regulates chemokine signaling via CX3CR12019

    • Author(s)
      Hiroki Hayashi, Hironori Nakagami
    • Organizer
      The 3rd Asia Australia Vascular Biology Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08515
  • [Presentation] 肥満病態におけるMyoferlinの新規機能解明2019

    • Author(s)
      野里陽一、鷹見洋一、山本浩一、中神啓徳、華山力成、楽木宏実
    • Organizer
      第23回日本心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] 脂肪分化及び肥満形成におけるMyoferlinの機能解明2019

    • Author(s)
      野里陽一、鷹見洋一、山本浩一、中神啓徳、華山力成、楽木宏実
    • Organizer
      第42回日本高血圧学会総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] Myoferlinは脂肪分化を介して肥満を形成する2018

    • Author(s)
      野里陽一、鷹見洋一、中神啓徳、山本浩一、華山力成、樂木宏実
    • Organizer
      第54回高血圧関連疾患モデル学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] 加齢性動脈硬化における脱ユビキチン化酵素CYLD(cylindomatosis)の関与2018

    • Author(s)
      鷹見洋一、今泉友希、山本浩一、中神啓徳、楽木宏実
    • Organizer
      第22回 心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] ループス腎炎モデルにおける抗 IL17A ワクチンの有効性2018

    • Author(s)
      池田裕香、中神啓徳、森下竜一
    • Organizer
      脳心血管抗加 齢研究会2018 (第16回学術集会)
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Effect of anti-cytokine vaccine in lupus-like nephritis mode2018

    • Author(s)
      池田裕香、郡山弘、中神啓徳、森下竜一
    • Organizer
      第 47 回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Myoferin-mediated lysosomal exocytosis of macophages regulates obesity-induced adipose inflammation2018

    • Author(s)
      Yoichi Nozato, Yoichi Takami, Hironori Nakagami, Koichi Yamamoto, Rikinari Hanayama, Hiromi Rakugi
    • Organizer
      27th Scientific Meeting of the Inernational Society of Hypertension (ISH 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08476
  • [Presentation] Efficacy of anti-IL17A vaccine in lupus-like nephritis model2018

    • Author(s)
      池田裕香、中神啓徳、森下竜一
    • Organizer
      第 16 回 日韓血管生物合同シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Confirmation of HLA-B27 Transgenic Rats as a spondyloarthritis model2018

    • Author(s)
      Tetsuya Tomita, Hiroki Hayashi, Sun Jiao, Hironori Nakagami
    • Organizer
      26th annual meeting European Orthopaedic Reseach Society
    • Data Source
      KAKENHI-PROJECT-18K09103
  • [Presentation] 高血圧治療を目指したワクチン開発2017

    • Author(s)
      中神啓徳
    • Organizer
      第40回日本高血圧学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] 高血圧ワクチン開発への挑戦2017

    • Author(s)
      中神啓徳
    • Organizer
      第53回高血圧関連疾患モデル学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] Development of Therapeutic Vaccine for Hypertension and Diabetes2017

    • Author(s)
      Hironori Nakagami
    • Organizer
      Dusan Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] Development of therapeutic vaccines as an antibody therapy2017

    • Author(s)
      Hironori Nakagami
    • Organizer
      15th Japan-Korea Joint Symposium of Vascular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] 次世代バイオロジクスとしての高血圧ワクチンの臨床応用2016

    • Author(s)
      中神啓徳
    • Organizer
      臨床高血圧フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] PIVOTAL ROLES OF DEUBIQIUTINATING ENZYME CYLD (CYLINDROMATOSIS) IN DEVELOPMENT OF AGEING-RELATED ATHEROSCLEROSIS IN THE VASCULATURE.2016

    • Author(s)
      Imaizumi Y, Takami Y, Yamamoto K, Nakagami H, Rakugi H
    • Organizer
      The 26th Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-09-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] Develop a therapeutic vaccine for angiotensin II2016

    • Author(s)
      Hironori Nakagami
    • Organizer
      International Society of Hypertension
    • Place of Presentation
      Seoul, Korea
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] ンジオテンシンⅡを標的とした高血圧・心不全ワクチンの開発2016

    • Author(s)
      中神啓徳
    • Organizer
      日本高血圧学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-16K09514
  • [Presentation] 関節炎に対するIL-17ワクチンによる新規治療法の開発2016

    • Author(s)
      郡山弘、冨田哲也、中神啓徳
    • Organizer
      第27回日本日本脊椎関節炎学会
    • Place of Presentation
      東京
    • Year and Date
      2016-09-23
    • Data Source
      KAKENHI-PROJECT-15K10470
  • [Presentation] 高血圧を標的としたDNAワクチンの開発2015

    • Author(s)
      中神 啓徳
    • Organizer
      第15回日本抗加齢医学会
    • Place of Presentation
      福岡
    • Year and Date
      2015-05-30
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] Angiotensin II Vaccine May One Day Help Lower Blood Pressure2015

    • Author(s)
      中神 啓徳
    • Organizer
      第38回日本高血圧学会
    • Place of Presentation
      松山
    • Year and Date
      2015-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04803
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第57回日本老年医学会学術集会、総会
    • Place of Presentation
      横浜
    • Year and Date
      2015-06-14
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 高血圧ワクチンの開発2015

    • Author(s)
      中神 啓徳
    • Organizer
      第88回日本内分泌学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2015-04-25
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] Angiotensin II Vaccine May One Day Help Lower Blood Pressure2015

    • Author(s)
      中神 啓徳
    • Organizer
      第38回日本高血圧学会
    • Place of Presentation
      愛媛
    • Year and Date
      2015-10-10
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 高血圧を標的としたDNAワクチンの開発2015

    • Author(s)
      中神 啓徳
    • Organizer
      第15回日本抗加齢医学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2015-05-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第38回日本高血圧学会総会
    • Place of Presentation
      松山
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 加齢に伴う動脈硬化形成過程における脱ユビキチン化酵素CYLD(cylindromatosis)のマクロファージの泡沫化への影響2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      CVMW2015心血管代謝週間
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 加齢に伴う動脈硬化形成過程におけるマクロファージでの脱ユビキチン化酵素CYLD(cylindromatosis)の病態生理的役割の検討2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      第51回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] 加齢に伴う動脈硬化形成過程における脱ユビキチン化酵素CYLD(cylindromatosis)のマクロファージの泡沫化への影響2015

    • Author(s)
      今泉 友希、鷹見 洋一、山本 浩一、中神 啓徳、樂木 宏実
    • Organizer
      12月 第10回 高血圧と冠動脈疾患研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-12-19
    • Data Source
      KAKENHI-PROJECT-15K08914
  • [Presentation] Development of therapeutic vaccine for hypertension2015

    • Author(s)
      中神 啓徳
    • Organizer
      第21回国際個別化医療学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] DNA Vaccine Technology as Novel Therapy for Hypertension2014

    • Author(s)
      中神 啓徳
    • Organizer
      第20回日本遺伝子治療学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-08-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670267
  • [Presentation] 高血圧ワクチン開発に向けた基礎的検討2014

    • Author(s)
      中神 啓徳
    • Organizer
      第3回臨床高血圧フォーラム
    • Place of Presentation
      広島
    • Year and Date
      2014-05-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670267
  • [Presentation] Novel Pathophysiological Roles of α synuclein, Causative Molecule of Parkinson's Disease, in Aging-related Metabolic Syndrome.2014

    • Author(s)
      Takami Y, Nakagami H, Garardo R, Yamamoto K, et al.
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      京都
    • Year and Date
      2014-04-15
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] Therapeutic vaccine against DPP4 improves glucose metabolism in mice2014

    • Author(s)
      中神 啓徳
    • Organizer
      第14回日本抗加齢医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-07
    • Data Source
      KAKENHI-PROJECT-25670433
  • [Presentation] Alpha-synuclein, Causative Molecule of Parkinson's Disease, Plays Significant Pathophysiological Roles in Aging-Related Metabolic Syndrome.2014

    • Author(s)
      Takami Y, Nakagami H, Garardo R, Yamamoto K, et al.
    • Organizer
      10th International Congress of the European Union Geriatric Medicine Society
    • Place of Presentation
      ロッテルダム(オランダ)
    • Year and Date
      2014-09-19
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] 高血圧ワクチンの歴史とその必要性2014

    • Author(s)
      中神 啓徳
    • Organizer
      第21回日本未病システム学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-01
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 次世代バイオロジクスとしての高血圧ワクチン開発2014

    • Author(s)
      中神 啓徳
    • Organizer
      第37回日本高血圧学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-10-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670267
  • [Presentation] 高血圧ワクチン開発に向けた基礎的検討2014

    • Author(s)
      中神 啓徳
    • Organizer
      第3回臨床高血圧フォーラム
    • Place of Presentation
      広島
    • Year and Date
      2014-05-24
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 次世代バイオロジクスとしての高血圧ワクチン開発2014

    • Author(s)
      中神 啓徳
    • Organizer
      第37回日本高血圧学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 高血圧症に対するDNAワクチンー高血圧自然発症ラット(SHR)モデルにおけるアンジオテンシンIIDNAワクチン治療法の開発2013

    • Author(s)
      郡山 弘、中神 啓徳、勝谷 友宏
    • Organizer
      第55回日本老年医学会学術集会・第28回日本老年学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 血中アルファシヌクレインと老化・糖代謝との関連解析2013

    • Author(s)
      中神 啓徳
    • Organizer
      日本抗加齢医学会シンポジウム
    • Place of Presentation
      パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] Long Term Blood Pressure Reduction by AngiotensinIIDNA Vaccine in Spontaneously Hypertensive Rats Model2013

    • Author(s)
      郡山 弘、中神 啓徳、勝谷 友宏
    • Organizer
      American Heart Association, Scientific Session 2013
    • Place of Presentation
      ヒューストン、アメリカ
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 高血圧症に対するDNAワクチンによる新規治療法の開発2013

    • Author(s)
      郡山 弘、中神 啓徳、勝谷 友宏
    • Organizer
      脳心血管抗加齢研究会2013
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 血中アルファシヌクレインと老化・糖代謝との関連解析2013

    • Author(s)
      中神啓徳
    • Organizer
      第13回抗加齢医学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] Challenge of novel therapeutic vaccines for Angiotensin IIor VEGF2013

    • Author(s)
      中神 啓徳
    • Organizer
      Seoul Brain Barrier Symposium
    • Place of Presentation
      ソウル、韓国
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] Parkinson病関連分子αシヌクレインの心血管疾患への関与2013

    • Author(s)
      鷹見 洋一、中神 啓徳、山本 浩一、神出 計、大石 充、楽木 宏実
    • Organizer
      第55回 日本老年医学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] 血中アルファシヌクレインと老化・糖代謝との関連解析2013

    • Author(s)
      中神啓徳
    • Organizer
      第13回日本抗加齢医学会総会
    • Place of Presentation
      横浜<シンポジウム>
    • Year and Date
      2013-06-28
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] DNAワクチンを用いた高血圧新規治療2013

    • Author(s)
      中神 啓徳
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] アンジオテンシンIIを標的とした高血圧ワクチンの実験動物での検討2013

    • Author(s)
      中神 啓徳
    • Organizer
      第36回日本高血圧学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] 次世代治療としての高血圧ワクチンへの挑戦2013

    • Author(s)
      中神 啓徳
    • Organizer
      Young Investigator Research Forum
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-25461127
  • [Presentation] アンジオテンシンIIを標的とした高血圧ワクチンの基礎研究2012

    • Author(s)
      中神啓徳
    • Organizer
      第1回臨床高血圧フォーラム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23659418
  • [Presentation] 高齢者高血圧患者におけるアンジオテンシン受容体拮抗薬による骨密度減少の抑制効果2012

    • Author(s)
      青木元邦、湯久浩、守口篤、志水秀朗、中神啓徳、荻原俊男、森下竜一
    • Organizer
      日本高血圧学会第一回臨床高血圧フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2012-05-12
    • Data Source
      KAKENHI-PROJECT-23590902
  • [Presentation] コレステロール代謝・輸送系制御機構における細胞機能・老化の解析2012

    • Author(s)
      勝谷友宏、郡山弘、中神啓徳、森下竜一
    • Organizer
      第54回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Presentation] Alpha synuclein and the glucose metabolism2012

    • Author(s)
      Hironori Nakagami, Gerardo Rodriguez-Araujo
    • Organizer
      第3回Molecular Cardiovascular ConferenceII
    • Place of Presentation
      キロロ<ポスター>
    • Year and Date
      2012-09-08
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] Alpha-synuclein is associated with impaired Glucose Regulation and Insulin Resistance2011

    • Author(s)
      中神啓徳
    • Organizer
      血管生物医学会学術集会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] 高血圧自然発症ラット(SHR)モデルにおけるアンジオテンシン II ワクチン治療法の開発2011

    • Author(s)
      森下竜一、中神啓徳
    • Organizer
      第34回日本高血圧学会
    • Place of Presentation
      宇都宮
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-23659418
  • [Presentation] Alpha-synuclein is associated with impaired glucose regulation and insulin resistance2011

    • Author(s)
      中神啓徳
    • Organizer
      第19回血管生物医学会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-22390186
  • [Presentation] Alpha-synuclein is associated with impaired glucose regulation and insulin resistance2011

    • Author(s)
      中神啓徳
    • Organizer
      第19回血管生物医学会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Presentation] Development of DNA vaccine for high blood pressure -Immunotherapy for angiotensin II -2011

    • Author(s)
      中神啓徳
    • Organizer
      第18回日本遺伝子治療学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2011-07-17
    • Data Source
      KAKENHI-PROJECT-23659418
  • [Presentation] Pivotal role of CYLD(Cylindromatosis)asa Deuhiquitinating enzyme in vasculature2008

    • Author(s)
      鷹見洋一、中神啓徳, 他
    • Organizer
      日本循環器学会
    • Place of Presentation
      マリンメッセ福岡
    • Year and Date
      2008-03-28
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Presentation] Ubiquitin carboxyl-terminal hydrolase Li, a novel deubiquitinating enzyme in vasculature2007

    • Author(s)
      Yoichi Takami, Hironori Nakagami, et.al.
    • Organizer
      plays a pivotal roles in vascular remodeling through the inhibition of NF-KB activation
    • Place of Presentation
      Orland, USA
    • Year and Date
      2007-11-04
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Presentation] 脱ユビキチン化酵素と動脈硬化2007

    • Author(s)
      中神啓徳
    • Organizer
      血管生物医学会
    • Place of Presentation
      日九州大学百年講堂
    • Year and Date
      2007-12-14
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Presentation] Pivotal role of CYLD (Cylindromatosis) as a Deubiquitinating enzyme in vasculature2007

    • Author(s)
      Yoichi Takami, Hironori Nakagami, et.al.
    • Place of Presentation
      Orland, USA
    • Year and Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-19590861
  • [Presentation] パーキンソン病関連分子αシヌクレインの新規機能-加齢性疾患としてのメタボリック症候群及びその心血管合併症の病態での役割-

    • Author(s)
      鷹見洋一、中神啓徳、神出計、山本浩一、森下竜一、金田安史、樂木宏実
    • Organizer
      第21回 日本血管生物医学会学術集会(YIA最優秀賞)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] パーキンソン病関連分子αシヌクレインの老化関連疾患における新規機能-メタボリック症候群及び血管内皮機能への関与-

    • Author(s)
      鷹見 洋一、大石 充、中神 啓徳、神出 計、山本 浩一、金田 安史、楽木 宏実
    • Organizer
      日本高血圧学会 第1回 臨床高血圧フォーラム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] Novel Pathophysiological Roles of alpha-synuclein, Causative Molecule of Parkinson’s Disease, in Aging-related Metabolic Syndrome.

    • Author(s)
      Yoichi Takami * , Hironori Nakagami , Rodriguez-Araujo Gerardo , Koichi Yamamoto , Ryuichi Morishita, Yasufumi Kaneda , Hiromi Rakugi
    • Organizer
      18th International Vascular Biology Meeting
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] Parkinson 病関連分子α シヌクレインの心血管疾患への関与

    • Author(s)
      鷹見洋一、中神啓徳、山本浩一、神出計、大石充、樂木宏実
    • Organizer
      第55回 日本老年医学会学術集会(合同選抜ポスター優秀賞)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24790756
  • [Presentation] パーキンソン病原因分子αシヌクレインの加齢によるメタボリック症候群における病態生理的役割

    • Author(s)
      鷹見洋一、中神啓徳、神出計、山本浩一、森下竜一、金田安史、樂木宏実
    • Organizer
      第36回 日本高血圧学会総会(Top10演題)
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24790756
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