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FUKUHARA TAKESHI  福原 武志

… Alternative Names

FUKUHARA takeshi  福原 武志

FUKUHARA Takeshi  福原 武志

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Researcher Number 20359673
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-2950-9516
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員
Affiliation (based on the past Project Information) *help 2021 – 2022: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 研究員
2020: 順天堂大学, 医学(系)研究科(研究院), 非常勤講師
2018 – 2019: 順天堂大学, 医学(系)研究科(研究院), 准教授
2017: 順天堂大学, 医学部, その他
2016: 順天堂大学, 医学(系)研究科(研究院), 准教授 … More
2016: 順天堂大学, 大学院医学研究科, 准教授
2013 – 2015: 東京薬科大学, 生命科学部, 助教
2005: 東京医科歯科大学, 難治疾患研究, 助手
2004 – 2005: 東京医科歯科大学, 難治疾患研究所, 助手
2003: 東京医科歯科大学, 大学院・疾患生命科学研究部, 助手 Less
Review Section/Research Field
Principal Investigator
Tumor therapeutics / Basic Section 51030:Pathophysiologic neuroscience-related / Complex Systems Disease Theory / Biological Sciences
Except Principal Investigator
Biological Sciences / Basic Section 29020:Thin film/surface and interfacial physical properties-related / Integrative animal science / Neurology / General medical chemistry / Tumor therapeutics
Keywords
Principal Investigator
イムノトキシン / 機能性抗体 / 抗体 / 炎症 / パーキンソン病 / 血管新生 / モノクローナル抗体 / Rotenone / Parkin / PARK2 … More / 炎症血管 / イムノリポソーム / 血管 / 老化 / アストロサイト / 免疫 / 腫瘍血管 / 血管新生誘導因子 / miR / 分泌顆粒 / 間質 / がん微小環境 / 抗体治療 / Secretome / メラノーマ / 単球 / 血管内皮細胞 / 血液脳関門 / CAGE解析 / トランスオミクス / オミクス解析 / トランスクリプトーム / 炎症性サイトカイン / バイオマーカー / scFv / 悪性黒色腫 / IL13Ra2 / SR / ウイルス / CMV / SARS / HIV / SRPK / キナーゼ阻害剤 / キナーゼ / スプライシング … More
Except Principal Investigator
選択的スプライシング / CLASP / Clk / mRNA / RNA結合タンパク質 / 組織特異性 / 線虫 / 初期化 / 細胞接着性 / 生体内環境 / sp3/sp2 / 内膜化 / DLC:N / 表面機能 / 細胞機能 / 窒素含有DLC / 窒素含有 / 細胞親和性 / ダイヤモンド状炭素膜 / 卵母細胞 / 体細胞核移植 / クローン / 核移植 / iPS細胞 / リプログラミング / 神経変性疾患 / 神経変性 / 脳・神経 / 内科 / パーキンソン病 / リソソーム / オートファジー / 神経内科学 / virus / alternative splicing / 蛋白リン酸化酵素阻害剤 / Sty / SR蛋白質 / TG003 / 4 / Clk1 / インシュリン / 抗ウイルス薬 / SRPIN340 / SRPK / ウイルス / 腫瘍溶解ウイルス療法 / がん / 抗体 / ヘルペスウイルス / 腫瘍溶解性ウイルス療法 / 遺伝子治療 / 核小体低分子RNA / RNA結合蛋白質 / 試験管内反応系 / RNA安定性制御 / RNAスプライシング / 遺伝子発現制御 / 品質管理 / 試験管内系 / RNA干渉 / イントロン / RNAプロセシング / RNA / RNAプロセッシング / レポーター / 変異体 / GFP / 可視化技術 / 蛍光タンパク質 / プレmRNA / PGCクローン / 体細胞クローン / エピジェネティクス / ゲノムインプリンティング機構の進化 / 有袋類におけるゲノムインプリンティング / Grb10とインスリン抵抗性 / Meg1 / コートアクチンと精子形態形成 / GS細胞 / 生殖細胞クローンの発生 / 父親型インプリンティング / 精子形成のエピジェネティクス / 新生児の成長異常 / 2型糖尿病 / 胎盤形成 / レトロトランスポゾン / 哺乳衣類の進化(系統発生) / 体細胞クローンの胎児異常 / 体細胞クローンの胎盤異常 / mUPD14 / ヒトp / 父親性・母親性2倍体 / 新生児致死 / 胎児期後期致死 / Rt11 / インプリンティング遺伝子Peg11 / インプリンティング遺伝子Peg10 / 生殖医療とエピジェネティクス / 再生医療とエピジェネティクス / 個体発生とヒト遺伝子疾患 / 胎盤形成と胎生機構 / 哺乳類の個体発生 / 体細胞クローン動物 / ゲノムインプリンティング Less
  • Research Projects

    (14 results)
  • Research Products

    (65 results)
  • Co-Researchers

    (31 People)
  •  High dimensional analysis of neurovasculature to reveal molecular mechanism of aged or neurodegenerative brainPrincipal Investigator

    • Principal Investigator
      Fukuhara Takeshi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Institute of Physical and Chemical Research
      Juntendo University
  •  Effect of N-containing DLC on cell adhesion and intimal proliferation in in-vivo test

    • Principal Investigator
      OHGOE YASUHARU
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 29020:Thin film/surface and interfacial physical properties-related
    • Research Institution
      Tokyo Denki University
  •  Transomics analysis of neuroimmune interaction in Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      Fukuhara Takeshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Complex Systems Disease Theory
    • Research Institution
      Juntendo University
  •  Secretome analysis of tumor microenvironment for developing immunotherapeuticsPrincipal Investigator

    • Principal Investigator
      Fukuhara Takeshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Juntendo University
  •  Development of anti-PD chemicals modulating autophagic activity based on lysosomal function

    • Principal Investigator
      Shinji Saiki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Juntendo University
  •  Acceleration an selection of somatic nuclear reprogramming based on nuclear remodelling

    • Principal Investigator
      TANI Tetsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Integrative animal science
    • Research Institution
      Kindai University
  •  Augmentation of tumor specificity and killing activity of oncolytic herpes virus vectors

    • Principal Investigator
      Uchida Hiroaki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      The University of Tokyo
      Tokyo University of Pharmacy and Life Science
  •  IL13Ra2, therapeutic target of melanoma, identified by unique antibody screening technology.Principal Investigator

    • Principal Investigator
      FUKUHARA takeshi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  生体における組織特異的選択的スプライシング制御機構の解明

    • Principal Investigator
      黒柳 秀人
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  核内RNPリモデリングと品質管理機構の解明

    • Principal Investigator
      廣瀬 哲郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  選択的スプライシングを制御する遺伝子および制御される遺伝子の探索

    • Principal Investigator
      KUROYANAGI Hidehito
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  新規リン酸化酵素阻害剤によるスプライシング制御とエイズウイルスの複製阻害Principal Investigator

    • Principal Investigator
      福原 武志
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Manipulation of aberrant splicing.

    • Principal Investigator
      HAGIWARA Masatoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  個体発生における生殖細胞系列と体細胞系列のエピジェネティクス

    • Principal Investigator
      石野 史敏
    • Project Period (FY)
      2003 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2006 Other

All Journal Article Presentation Book Patent

  • [Book] 機能性抗体の探索とイムノリポソーム開発による神経変性疾患の創薬創発へ2019

    • Author(s)
      福原武志、服部信孝
    • Publisher
      北隆館 Precision Medicine
    • ISBN
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Book] 機能性抗体の探索から新しい治療モダリティの創薬へ ー神経変性疾患載せらのスティクス開発に有望なエピトープを探して2019

    • Author(s)
      福原武志
    • Publisher
      北隆館 Precision Medicine
    • ISBN
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Journal Article] Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury.2021

    • Author(s)
      Enzhi Yin, Takeshi Fukuhara, Kazuyoshi Takeda, Yuko Kojima, Kyoko Fukuhara, Kenichi Ikejima, Hisashi Bashuda, Jiro Kitaura, Hideo Yagita, Ko Okumura, Koichiro Uchida
    • Journal Title

      Scientific Reports

      Volume: 6322 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-021-85001-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-20K17000, KAKENHI-PROJECT-18H02695, KAKENHI-PROJECT-20H03721, KAKENHI-PROJECT-21K07922
  • [Journal Article] Novel method for screening functional antibody with comprehensive analysis of its immunoliposome2021

    • Author(s)
      Hamamichi Shusei、Fukuhara Takeshi、Umeda Izumi O.、Fujii Hirofumi、Hattori Nobutaka
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41598-021-84043-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H01095, KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-18H04169, KAKENHI-PLANNED-18H05463
  • [Journal Article] α-Synuclein Seeding Assay Using RT-QuIC.2021

    • Author(s)
      Okuzumi Ayami、Hatano Taku、Fukuhara Takeshi、Ueno Shinichi、Nukina Nobuyuki、Imai Yuzuru、Hattori Nobutaka
    • Journal Title

      Methods Mol Biol.

      Volume: 2322 Pages: 3-16

    • DOI

      10.1007/978-1-0716-1495-2_1

    • ISBN
      9781071614945, 9781071614952
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-19K16928
  • [Journal Article] Demon slayer? Targeting myeloid cells for modulating neuroinflammation2020

    • Author(s)
      Takeshi Fukuhara, Taku Hatano, Nobutaka Hattori
    • Journal Title

      Bio clinica

      Volume: 9 Pages: 153-155

    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Journal Article] Immunotoxin screening system: A rapid and direct approach to obtain functional antibodies with internalization capacities2020

    • Author(s)
      Shusei Hamamichi, Takeshi Fukuhara, Nobutaka Hattori
    • Journal Title

      Toxins

      Volume: 12 Issue: 10 Pages: 1-15

    • DOI

      10.3390/toxins12100658

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Journal Article] Prenatal exposure to valproic acid is associated with altered neurocognitive function and neurogenesis in the dentate gyrus of male offspring rats.2019

    • Author(s)
      Tomoya Kinjo, Masanobu Ito, Tatsunori Seki, Takeshi Fukuhara, Kuerban Bolati, Heii Arai, Toshihito Suzuki
    • Journal Title

      Brain Research

      Volume: 1723 Pages: 146403-146403

    • DOI

      10.1016/j.brainres.2019.146403

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07571, KAKENHI-PROJECT-19K07831
  • [Journal Article] Interleukin-13 receptor α2 is a novel marker and potential therapeutic target for human melanoma.2019

    • Author(s)
      Okamoto H*, Yoshimatsu Y*, Tomizawa T*, Kunita A*, Takayama R*, Morikawa T, Komura D, Takahashi K, Oshima T, Sato M, Komai M, Podyma-Inoue KA, Uchida H, Hamada H, Fujiu K, Ishikawa S, Fukayama M, Fukuhara T, Watabe T. (* equal contributor)
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 1281-1281

    • DOI

      10.1038/s41598-019-39018-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15611, KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-16K08614
  • [Journal Article] Multi-year whole-blood transcriptome data for the study of onset and progression of Parkinson's Disease.2019

    • Author(s)
      Valentine MNZ, Hashimoto K, Fukuhara T, Saiki S, Ishikawa KI, Hattori N, Carninci P.
    • Journal Title

      Sci Data

      Volume: 6 Issue: 1 Pages: 1-7

    • DOI

      10.1038/s41597-019-0022-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07831, KAKENHI-PROJECT-18K15463
  • [Journal Article] パーキンソン病における脳と末梢炎症の臓器連関2018

    • Author(s)
      福原武志
    • Journal Title

      Medical Science Digest

      Volume: 44 Pages: 71-74

    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Journal Article] Rapid dissemination of alpha-synuclein seeds through neural circuits in an in-vivo prion-like seeding experiment2018

    • Author(s)
      Okuzumi Ayami、Kurosawa Masaru、Hatano Taku、Takanashi Masashi、Nojiri Shuuko、Fukuhara Takeshi、Yamanaka Tomoyuki、Miyazaki Haruko、Yoshinaga Saki、Furukawa Yoshiaki、Shimogori Tomomi、Hattori Nobutaka、Nukina Nobuyuki
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 6 Issue: 1 Pages: 96-96

    • DOI

      10.1186/s40478-018-0587-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17KT0131, KAKENHI-PUBLICLY-17H05705, KAKENHI-PUBLICLY-18H04564, KAKENHI-PROJECT-17H01564, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-16H04768, KAKENHI-PROJECT-18H02723, KAKENHI-PROJECT-15K06762, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-18H00446, KAKENHI-PROJECT-17KT0130
  • [Journal Article] 脈管系の機能制御から考えるパーキンソン病の炎症と臓器連関2018

    • Author(s)
      福原武志
    • Journal Title

      Bio Clinica

      Volume: 7 Pages: 148-153

    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Journal Article] Multi-organ failure with systemic inflammation, leading to Parkinson's disease pathogenesis.2018

    • Author(s)
      Takeshi Fukuhara
    • Journal Title

      Medical Science Digest

      Volume: 44/3 Pages: 71-74

    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Journal Article] A novel immunotoxin reveals a new role for CD321 in endothelial cells2017

    • Author(s)
      Fukuhara Takeshi、Kim Jia、Hokaiwado Shintaro、Nawa Makiko、Okamoto Hayato、Kogiso Tomohiko、Watabe Tetsuro、Hattori Nobutaka
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 10 Pages: e0181502-e0181502

    • DOI

      10.1371/journal.pone.0181502

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08614, KAKENHI-PROJECT-17KT0130, KAKENHI-PROJECT-16K07184
  • [Journal Article] Decreased long-chain acylcarnitines from insufficient β-oxidation as potential early diagnostic markers for Parkinson's disease.2017

    • Author(s)
      Saiki S, Hatano T, Fujimaki M, Ishikawa K, Mori A, Oji Y, Okuzumi A, Fukuhara T, Koinuma T, Nagumo M, Furuya N, Nojiri S, Amo T, Yamashiro K, Hattori N.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 7328-7328

    • DOI

      10.1038/s41598-017-06767-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-17K09769, KAKENHI-PLANNED-25111007, KAKENHI-PROJECT-15H04843, KAKENHI-PROJECT-15K09325
  • [Journal Article] Development of an oncolytic HSV vector fully retargeted specifically to cellular EpCAM for virus entry and cell-to-cell spread.2016

    • Author(s)
      Shibata T, Uchida H, Shiroyama T, Okubo Y, Suzuki T, Ikeda H, Yamaguchi M, Miyagawa Y, Fukuhara T, Cohen JB, Glorioso JC, Watabe T, Hamada H, Tahara H.
    • Journal Title

      Gene Therapy.

      Volume: 印刷中 Issue: 6 Pages: 479-488

    • DOI

      10.1038/gt.2016.17

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15144, KAKENHI-PROJECT-25290059, KAKENHI-PROJECT-15K06876, KAKENHI-PROJECT-16K08249, KAKENHI-PROJECT-16K07184
  • [Journal Article] Novel hybrid compound of a plinabulin prodrug with an IgG binding peptide for generating a tumor selective noncovalent-type antibody-drug conjugate2016

    • Author(s)
      Muguruma K, Yakushiji F, Kawamata R, Akiyama D, Arima R, Shirasaka T, Kikkawa Y, Taguchi A, Takayama K, Fukuhara T, Watabe T, Ito Y, Hayashi Y
    • Journal Title

      Bioconjug Chem

      Volume: 27 Issue: 7 Pages: 1606-1613

    • DOI

      10.1021/acs.bioconjchem.6b00149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26430123, KAKENHI-PROJECT-15J09551, KAKENHI-PROJECT-16K07184
  • [Journal Article] TGF-βシグナルからみた血管制御の均衡と破綻.2014

    • Author(s)
      福原武志、渡部徹郎
    • Journal Title

      日本血栓止血学会誌

      Volume: 25 Pages: 609-614

    • NAID

      130004700439

    • Data Source
      KAKENHI-PROJECT-25830123
  • [Journal Article] A single cell extraction chip using vibration-induced whirling flow and a, thermo-responsive gel pattern2014

    • Author(s)
      Takeshi Hayakawa, Shinya Sakuma, Takeshi Fukuhara, Yoshiyuki Yokoyama and Fumihito Arai
    • Journal Title

      Micromachines

      Volume: 5 Issue: 3 Pages: 681-696

    • DOI

      10.3390/mi5030681

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J03580, KAKENHI-PROJECT-25830123
  • [Journal Article] Utilization of host SR protein kinases and RNA-splicing machinery during viral replication.2006

    • Author(s)
      Fukuhara, T
    • Journal Title

      Proc Natl Acad Sci USA 103(30)

      Pages: 11329-11333

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390074
  • [Journal Article] Utilization of host SR protein kinases and RNA-splicing machinery during viral replication.2006

    • Author(s)
      Fukuhara T
    • Journal Title

      Proc Natl Acad Sci USA 103(30)

      Pages: 11329-11333

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390074
  • [Patent] 非結晶炭素膜の細胞凝集機能を判定する検査方法。2020

    • Inventor(s)
      大越康晴,鬼頭大海,中森秀樹,平塚傑工,福原武志
    • Industrial Property Rights Holder
      大越康晴,鬼頭大海,中森秀樹,平塚傑工,福原武志
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-188369
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K04943
  • [Patent] 融合タンパク質、 それをコードするポリヌクレオチドおよびそれらの用途2016

    • Inventor(s)
      藤川雄太、福原武志、井上英史
    • Industrial Property Rights Holder
      藤川雄太、福原武志、井上英史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-05-10
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Patent] アミロイドβタンパク質オリゴマー用モノクローナル抗体及びその利用2016

    • Inventor(s)
      田平武、松本信英、服部信孝、福原武志、原英夫
    • Industrial Property Rights Holder
      田平武、松本信英、服部信孝、福原武志、原英夫
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-05-09
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 中性子反射率測定による細胞親和性窒素含有DLCの構造評価2021

    • Author(s)
      ファウズィア カマリナ,宮田登,福原武志,平栗健二,大越康晴
    • Organizer
      第34回ダイヤモンドシンポジウム
    • Data Source
      KAKENHI-PROJECT-18K04943
  • [Presentation] Novel method for screening functional antibody and its application toward generating drug delivery modality.2020

    • Author(s)
      Takeshi Fukuhara
    • Organizer
      第93回日本生化学会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] Effects of foreign element contents on functional a-C:H film structure for biomedical applications2019

    • Author(s)
      Y. Ohgoe, T. Fukuhara, N. Miyata, T. Yaguchi, A. Homma, and K. Hirakuri
    • Organizer
      7th International Symposium on Surfaces and Interfaces for Biomaterials
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] CD321 mAb (90G4) protects liver via inhibiting neutrophil infiltration in murine hepatic ischemia reperfusion model2019

    • Author(s)
      Enzhi Yin, Takeshi Fukuhara, Kazuyoshi Takeda, Hisashi Bashuda, Koichiro Uchida
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] 悪性黒色腫の血管新生及び腫瘍形成能におけるIL13Rα2の役割2019

    • Author(s)
      高山莉那、岡本勇人、吉松康裕、富澤泰志、国田朱子、高橋和樹、井上 カタジナアンナ、深山正久、福原武志、渡部徹郎
    • Organizer
      第27回日本血管生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] Effects of foreign element contents on functional a-C:H film structure for biomedical applications2019

    • Author(s)
      Y. Ohgoe, T. Fukuhara, N. Miyata, S. Tunmee, P. Kidkhunthod, T. Yaguchi, A. Homma, K. Hirakuri
    • Organizer
      ISSIB 2019 (7th International Symposium on Surfaces and Interfaces for Biomaterials
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K04943
  • [Presentation] 薬物送達能を示す機能性抗体の探索技術とイムノリポソーム開発による機能解析2019

    • Author(s)
      福原武志、濱道修生、服部信孝
    • Organizer
      日本DDS学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] 脳血管内皮細胞の多次元解析による老化に特徴的な亜集団の同定2019

    • Author(s)
      福原武志、濱道修生、服部信孝
    • Organizer
      Neuro2019, 第42回日本神経科学会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] Screening technology and application of functional antibody for brain diseases2019

    • Author(s)
      Takeshi Fukuhara
    • Organizer
      13th International Symposium on Nanomedicine, ISNM2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] 各種DLCの光学定数とsp3/sp2構造の違いに依存した細胞接着特性の評価2019

    • Author(s)
      鬼頭大海,大越康晴,福原武志,平塚傑工,Sarayut Tunmee, Ukit Rittihong, Chanan Euaruksakul , Hideki Nakajima, 中森秀樹,矢口俊之,本間章彦,平栗健二
    • Organizer
      第33回ダイヤモンドシンポジウム
    • Data Source
      KAKENHI-PROJECT-18K04943
  • [Presentation] 血管新生阻害剤に対する薬剤耐性を回避する新たな腫瘍兵糧攻め療法の開発2019

    • Author(s)
      加藤智尋、北村成史、徳永正之、濱田庸、鳩山恵一朗、高野真由美、福原武志、今井陽介、権田幸祐
    • Organizer
      第27回日本血管生物医学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] Effects of foreign element contents on functional a-C:H film structure for biomedical applications2019

    • Author(s)
      Y. Ohgoe, T. Fukuhara, N. Miyata, S. Tunmee, P. Kidkhunthod, T. Yaguchi, A. Homma, K. Hirakuri
    • Organizer
      7th International Symposium on Surfaces and Interfaces for Biomaterials
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K04943
  • [Presentation] 薬物送達能を示す機能性抗体の探索技術とイムノリポソーム開発による機能解析2019

    • Author(s)
      福原武志、濱道修生、服部信孝
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] alpha-synucleinの伝播抑制因子の探索と複合療法を開発2019

    • Author(s)
      奥住文美、波田野琢、福原武志、常見泰司、貫名信行、服部信孝
    • Organizer
      MSDJ2019, パーキンソン病運動障害疾患コングレス
    • Data Source
      KAKENHI-PROJECT-19K07831
  • [Presentation] 炎症やストレス応答性に形成される脳脈管系のCD146亜集団2018

    • Author(s)
      福原武志、竹田亮太、金井仁美、服部信孝
    • Organizer
      日本血管生物医学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] Screening technology for potent antibodies modulating endothelial cell functions2018

    • Author(s)
      Takeshi Fukuhara and Nobutaka Hattori
    • Organizer
      日本神経科学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] 内皮細胞を標的とした機能性抗体の探索とイムノリポソームによる動態解析2018

    • Author(s)
      福原武志、竹田亮太、濱道修生、金井仁美、服部信孝
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] 脳神経系への薬物送達を志向した機能性抗体の探索2017

    • Author(s)
      福原武志
    • Organizer
      日本神経科学会
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 血管内皮細胞を標的化するCD321イムノトキシンによる新たな機能の解析2017

    • Author(s)
      福原武志
    • Organizer
      日本血管生物医学会
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 脳神経系への薬物送達を志向した機能性抗体の探索2017

    • Author(s)
      福原武志
    • Organizer
      日本神経科学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] 血管内皮細胞を標的化するCD321イムノトキシンによる新たな機能の解析2017

    • Author(s)
      福原武志
    • Organizer
      日本血管生物医学会
    • Data Source
      KAKENHI-PROJECT-17KT0130
  • [Presentation] がんの抗体治療を志向した機能性抗体の探索技術開発2016

    • Author(s)
      福原武志
    • Organizer
      第20回日本がん分子標的治療学会
    • Place of Presentation
      大分 別府国際コンベンションセンター
    • Year and Date
      2016-05-30
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 感染症診断・治療・予防における多次元探索研究のすすめ2016

    • Author(s)
      福原武志
    • Organizer
      第65回感染症東日本・第63回化学療法東日本 合同学会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター
    • Year and Date
      2016-10-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 血管内皮細胞を標的化するモノクローナル抗体の機能解析2016

    • Author(s)
      福原武志
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K07184
  • [Presentation] 腫瘍細胞表面抗原を介して侵入する標的化単純ヘルペスウイルスベクターの開発2015

    • Author(s)
      城山智貴, 内田宏昭, 大久保優, 柴田智子, 福原武志, 山口美樹, Justus B. Cohen, Joseph C. Glorioso, 渡部徹郎, 濱田洋文, 田原秀晃
    • Organizer
      第7回血液疾患免疫療法研究会
    • Place of Presentation
      東京大学本郷キャンパス(東京都文京区)
    • Year and Date
      2015-09-26
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Syncytial mutations augment the oncolytic potential of a fully retargeted herpes simplex virus vector.2013

    • Author(s)
      Wakata A, Okubo Y, Fukuhara T, Cohen JB, Joseph C. Glorioso JC, Nakano K, Kumagai I, Kuroki M, Hamada H, Uchida H.
    • Organizer
      The 19th Annual Meeting of Japan Society of Gene Therapy.
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] エンベロープ糖タンパクgDにがん標的化単鎖抗体を挿入した単純ヘルペスウイルスを用いた腫瘍溶解ウイルス療法の開発2013

    • Author(s)
      鈴木拓真, 柴田智子, 大久保優, 福原武志, 宮川世志幸, Justus Cohen, Joseph Glorioso, 中野賢二, 熊谷泉, 黒木政秀, 山口美樹, 平井幸恵, 濱田洋文, 内田宏昭
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] 単純ヘルペスウイルスの標的化改変プラットフォームへのがん標的化抗体インハウスリソースの適用2013

    • Author(s)
      柴田智子, 鈴木拓真, 大久保優, 駒井麻央, 福原武志, 山口美樹, 平井幸恵, 宮川世志幸, Justus Cohen, Joseph Glorioso, 濱田洋文, 内田宏昭
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Manipulation of multiple herpes simplex virus glycoproteins for fully retargeted entry and efficient cell-to-cell spread.2013

    • Author(s)
      Wakata A, Okubo Y, Fukuhara T, Cohen JB, Glorioso JC, Nakano K, Kumagai I, Kuroki M, Hamada H, Uchida H.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] 独自の標的化抗体探索技術から見出したメラノーマの分子標的IL13Ra22013

    • Author(s)
      福原武志
    • Organizer
      日本生化学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] Application of in-house monoclonal antibody resources to a fully retargeted oncolytic herpes simplex virus platform.2013

    • Author(s)
      Okubo Y, Suzuki T, Shibata T, Komai M, Fukuhara T, Yamaguchi M, Hirai S, Miyagawa Y, Cohen JB, Glorioso JC, Hamada H, Uchida H.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Exploration of cancer-targeting antibodies using an HSV-based screening system.

    • Author(s)
      Okubo Y, Ikeda H, Fukuhara T, Kojima M, Cohen JB, Glorioso JC, Hamada H, Watabe T, Uchida H.
    • Organizer
      The 39th International Herpesvirus Workshop.
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2014-07-19 – 2014-07-23
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Development of a new generation of herpes simplex virus vectors fully retargeted to a variety of tumor-associated antigens.

    • Author(s)
      Uchida H, Okubo Y, Shibata T, Suzuki T, Ikeda H, Shiroyama T, Fukuhara T, Kojima M, Yamaguchi M, Miyagawa Y, Cohen JB, Glorioso JC, Hamada H.
    • Organizer
      The 20th Annual Meeting of Japan Society of Gene Therapy.
    • Place of Presentation
      東京慈恵会医科大学(東京都港区)
    • Year and Date
      2014-08-06 – 2014-08-08
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Identification of Interleukin 13 Receptor alpha 2 (IL13Rα2) as a novel marker of human melanoma.

    • Author(s)
      Mao Komai, Akiko Kunita, Teppei Morikawa, Hayato Okamoto, Moegi Sato, Hiroaki Uchida, Yasuhiro Yoshimatsu, Takeshi Fukuhara, Masashi Fukayama, Tetsuro Watabe
    • Organizer
      Joint International Symposium on TGF-β Family and Cancer
    • Place of Presentation
      tsukuba, JAPAN
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] Interleukin 13 receptor alpha 2 expression increases the growth of human melanoma xenograft in mice.

    • Author(s)
      Hayato Okamoto, Moegi Sato, Hiroaki Uchida, Yasuhiro Yoshimatsu, Takeshi Fukuhara, Tetsuro Watabe
    • Organizer
      Joint International Symposium on TGF-β Family and Cancer
    • Place of Presentation
      tsukuba, JAPAN
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] IL13Ra2, therapeutic target of melanoma, identified by unique antibody screening technology.

    • Author(s)
      Takeshi Fukuhara, Hirofumi Hamada, Hiroaki Uchida, and Tetsuro Watabe.
    • Organizer
      Joint International Symposium on TGF-β Family and Cancer
    • Place of Presentation
      tsukuba, JAPAN
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] Development of anti-EpCAM ScFv toxin for cancer therapeutics.

    • Author(s)
      Yuta Matsuura, Takeshi Fukuhara, Miho Ohsuga, Hiroaki Uchida, and Tetsuro Watabe.
    • Organizer
      Joint International Symposium on TGF-β Family and Cancer
    • Place of Presentation
      tsukuba, JAPAN
    • Year and Date
      2015-01-12 – 2015-01-13
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] メラノーマ新規バイオマーカーとして同定したIL13Rα2の機能解析.

    • Author(s)
      福原武志、佐藤萌希、岡本勇人、内田宏昭、濱田洋文、渡部徹郎
    • Organizer
      第87回 日本生化学会
    • Place of Presentation
      京都、日本
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25830123
  • [Presentation] Augmentation of oncolytic potential of a fully retargeted HSV vector by introduction of syncytial mutations.

    • Author(s)
      Wakata A, Okubo Y, Fukuhara T, Cohen JB, Glorioso JC, Nakano K, Kumagai I, Kuroki M, Hamada H, Watabe T, Uchida H.
    • Organizer
      The 39th International Herpesvirus Workshop.
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2014-07-19 – 2014-07-23
    • Data Source
      KAKENHI-PROJECT-25290059
  • [Presentation] Generation of an EpCAM-retargeted HSV vector by application of in-house monoclonal antibody resources.

    • Author(s)
      Shibata T, Shiroyama T, Suzuki T, Okubo Y, Fukuhara T, Yamaguchi M, Miyagawa Y, Cohen JB, Glorioso JC, Hamada H, Watabe T, Uchida H.
    • Organizer
      The 39th International Herpesvirus Workshop.
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2014-07-19 – 2014-07-23
    • Data Source
      KAKENHI-PROJECT-25290059
  • 1.  KUROYANAGI Hidehito (30323702)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  HAGIWARA Masatoshi (10208423)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  廣瀬 哲郎 (30273220)
    # of Collaborated Projects: 2 results
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    # of Collaborated Products: 11 results
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    # of Collaborated Products: 6 results
  • 6.  TAHARA HIDEAKI (70322071)
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    # of Collaborated Products: 2 results
  • 7.  Shinji Saiki (00339996)
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    # of Collaborated Products: 0 results
  • 8.  TANI Tetsuya (70319763)
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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  • 12.  OHGOE YASUHARU (10408643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  石野 史敏 (60159754)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  石野 知子 (20221757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  幸田 尚 (60211893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  井手上 賢 (20420250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  住吉 克彦 (10445471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  笹澤 有紀子 (20594922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  古屋 徳彦 (50401188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  井本 正哉 (60213253)
    # of Collaborated Projects: 1 results
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  • 21.  赤松 和土 (60338184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  石川 景一 (90733973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  本間 章彦 (20287428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 24.  宮田 登 (40465985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 25.  KUNITA Akiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  Hamamichi Shusei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  HATANO Taku
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  下郡 智美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  山中 智行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  吉川 大和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  渡部 徹郎
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