• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

KOSHIMIZU Taka-aki  輿水 崇鏡

ORCIDConnect your ORCID iD *help
… Alternative Names

輿水 崇鏡  コシミズ タカアキ

Less
Researcher Number 20392491
Other IDs
External Links
Affiliation (Current) 2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2019: 自治医科大学, 医学部, 教授
2007 – 2017: Jichi Medical University, 医学部, 准教授
2011: 自治医科大学, 医学研究科, 准教授
2007: 自治医科大学, 医学研究科, 准教授
2004 – 2007: 京都大学, 薬学研究科, 講師
Review Section/Research Field
Principal Investigator
General pharmacology / Anesthesiology / Biological pharmacy
Except Principal Investigator
Biological pharmacy / Biological Sciences / Applied pharmacology / Circulatory organs internal medicine / General pharmacology
Keywords
Principal Investigator
受容体 / 発光タンパク質 / 蛍光タンパク質 / 共鳴エネルギー移動 / ペプチドリガンド / ノックアウトマウス / バゾプレッシン / リガンド探索 / モルヒネ / 相互作用 … More / アロステリック効果 / シグナル複合体 / 高次複合体 / バゾプレシン / アレスチン / アデニレートサイクラーゼ / ゲノム編集 / オピオイド / 医療用麻薬 / 鎮痛耐性 / 薬理学的リネージ解析 / 質量分析 / ルシフェラーゼ / ヘテロ受容体 / 光振動エネルギー移動 / 広域親和性 / Pharmacology / Drug discovery / Receptor Interaction / Gタンパク質共役型受容体 / 受容体ダイマー / 受容体薬理学 / 発光蛋白質 / 蛍光蛋白質 / G蛋白質受容体 / 免疫沈降 / BRET / 受容体オリゴマー / 薬理学 / 創薬 / 受容体相互作用 / 発現組織分布 / ヘテロマー受容体 / オピオイド受容体 / モルヒネ作用(米国) / 複合体形成 / 受容体(米国) / 選択性 / ヘテロマー複合体 / 薬物受容体 / ステロイドホルモン / 副腎皮質 / リポフスチン / G蛋白質共役型受容体 / 生理活性 / 生体分子 / ナノバイオ / G蛋白共役型受容体 … More
Except Principal Investigator
GPR120 / DNAチップ / QT延長 / 臨床薬理学 / 薬理学 / GLP-1 / 分化 / 食道がん / 薬物有害反応 / 循環器 / GPR 40 family (GPR40,41,43) / GLP-1 (glucagon-like peptide 1) / Intracellular calcium / Free fatty acid / Enteroendocrine cell / Orphan G protein-coupled / リガンド / 遊離脂肪酸受容体 / ノックアウトマウス / ERK / カルシウムシグナル / 抗体 / GPR40 / G蛋白質共役型受容体 / GPR40ファミリー(GPR40,41,43) / GLP-1(グルカゴン様ペプチド-1) / 細胞内カルシウム / 遊離脂肪酸 / 腸管内分泌細胞 / オーファンG蛋白共役型受容体 / アルギニンメチル化酵素 / 蛋白質アルギニンメチル化 / 微小管 / PRMT5 / RASSF1A / ユビキチン化 / 上皮間葉転換 / 細胞周期 / ミトコンドリア / アグレソーム / 分子シャペロン / Sav1 / 心不全 / 線維化 / 心肥大 / 分子心臓病態学 / 白血病 / 有害反応 / ゲノム創薬科学 / フローサイトメーター / GPCR / バイオインフォマティックス / 疾患動物モデル / RNA / バイオインフォマッティックス / トランスクリプトーム / microRNA / がん / 上皮細胞 / miRNA / バイオマーカー / 乳がん / 発現プロファイル / 超高感度DNAチップ / ネットワーク解析 / マイクロRNA / 包括的トランスクリプトーム解析 / 3T3-L1 / siRNA / 脂肪細胞 / 脂肪酸 / ゲノム医療 / ゲノム情報 / バイオインフォマティクス / 食道癌 / 臨床検体 / マイクロアレイ / 個別化医療 / ゲノム解析 / 網羅的 / 微量臨床検体 / テーラーメード医療 / 高感度チップ / 高感度化 / 下垂体細胞 / ATP受容体 / P2X2受容体 / 共鳴エネルギー移動 / スプライシングバリアント / イオンチャネル / 蛍光蛋白質 / アデノシン三リン酸 / 下垂体機能 / 受容体相互作用 / プリン受容体チャネル Less
  • Research Projects

    (18 results)
  • Research Products

    (108 results)
  • Co-Researchers

    (28 People)
  •  Can we prevent analgesic tolerance to morphine? Study of high-order opioid receptor signal complex and its clinical application.Principal Investigator

    • Principal Investigator
      Koshimizu Taka-aki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology
    • Research Institution
      Jichi Medical University
  •  Development of analysis method of receptors using peptide wide affinity and resonance energy transferPrincipal Investigator

    • Principal Investigator
      Taka-aki Koshimizu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Jichi Medical University
  •  Development of a method to attenuate the adverse effect of anti-arrhythmic bepridil

    • Principal Investigator
      Fujimura Akio
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Jichi Medical University
  •  Research and application of allosteric ligands directed to G-protein coupled receptor heteromersPrincipal Investigator

    • Principal Investigator
      KOSHIMIZU Taka-aki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Jichi Medical University
  •  Functional regulation of novel tumor suppressor protein Sav1 by molecular chaperone

    • Principal Investigator
      SHIBATA Katsushi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Himeji Dokkyo University
  •  Functional role of PRMT5 for the RASSF1A-mediated tumor suppressive functions

    • Principal Investigator
      SHIRAKI Takashi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Himeji Dokkyo University
  •  Development of the method for reducing the adverse effect of arsenic trioxide

    • Principal Investigator
      FUJIMURA Akio
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Jichi Medical University
  •  Elucidation of novel mechanism in cardiac fibrosis

    • Principal Investigator
      IWANAGA Yoshitaka
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kinki University
  •  Physiological role of free fatty acid receptor GPR120.

    • Principal Investigator
      HIRASAWA Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Drug development using accelerated aging modelPrincipal Investigator

    • Principal Investigator
      KOSHIMIZU Taka-aki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Jichi Medical University
  •  New genome medicine and drug discovery based on the comprehensive transcriptome analysis

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Gタンパク質共役型受容体ヘテロマーを治療標的としたリガンド探索法の確立Principal Investigator

    • Principal Investigator
      輿水 崇鏡
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Jichi Medical University
  •  微量臨床検体発現プロファイルによるがんの個別化治療

    • Principal Investigator
      辻本 豪三
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  脂肪酸受容体を介する脂肪細胞機能調節機構の解明

    • Principal Investigator
      平澤 明
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  臨床ゲノム研究のための高感度ゲノム機能解析システムの開発

    • Principal Investigator
      辻本 豪三
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Identification of ligand and function of novel group of free fatty acid receptors by using genome information.

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  Strategic evaluation of Receptor interaction using resonance energy transferPrincipal Investigator

    • Principal Investigator
      KOSHIMIZU Takaaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyoto University
  •  ATP細胞間情報伝達作用の個体レベルでの解析

    • Principal Investigator
      TSUJIMOTO Gozoh
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] 標準医療薬学 薬理学2009

    • Author(s)
      輿水崇鏡
    • Total Pages
      11
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells2019

    • Author(s)
      Giesecke Torsten、Himmerkus Nina、Leipziger Jens、Bleich Markus、Koshimizu Taka-aki、F?hling Michael、Smorodchenko Alina、Shpak Julia、Knappe Carolin、Isermann Julian、Ayasse Niklas、Kawahara Katsumasa、Schmoranzer Jan、Gimber Niclas、Paliege Alexander、Bachmann Sebastian、Mutig Kerim
    • Journal Title

      Journal of the American Society of Nephrology

      Volume: 30 Issue: 6 Pages: 946-961

    • DOI

      10.1681/asn.2018080816

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Journal Article] Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance2018

    • Author(s)
      Koshimizu TA, et al.
    • Journal Title

      Nat Neurosci

      Volume: Epub ahead of print Issue: 6 Pages: 820-833

    • DOI

      10.1038/s41593-018-0144-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04323, KAKENHI-PROJECT-15K15055, KAKENHI-PROJECT-18K19404, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-17H01525, KAKENHI-PROJECT-17H03984
  • [Journal Article] Lipopolysaccharide-induced inflammation or unilateral ureteral obstruction yielded multiple types of glycosylated Lipocalin 2.2016

    • Author(s)
      Fujiwara Y, Tsuchiya H, Sakai N, Shibata K, Fujimura A, Koshimizu TA.
    • Journal Title

      J Inflamm

      Volume: 13 Issue: 1 Pages: 7-7

    • DOI

      10.1186/s12950-016-0116-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460658, KAKENHI-PROJECT-26860173
  • [Journal Article] Prostaglandin D2 elicits the reversible neurite retraction in hypothalamic cell line.2016

    • Author(s)
      Tsuchiya H, Hohjoh H, Fujiwara Y, Sugimoto Y, Koshimizu TA.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 470 Issue: 4 Pages: 804-810

    • DOI

      10.1016/j.bbrc.2016.01.091

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15055, KAKENHI-PROJECT-26670030, KAKENHI-PROJECT-24390017, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905
  • [Journal Article] Combined sodium ion sensitivity in agonist binding and internalization of vasopressin V1b receptors.2016

    • Author(s)
      Koshimizu TA, Kashiwazaki A, Taniguchi J.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 25327-25327

    • DOI

      10.1038/srep25327

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Journal Article] Subcellular localization and internalization of the vasopressin V1B receptor.2015

    • Author(s)
      Kashiwazaki A, Fujiwara Y, Tsuchiya H, Sakai N, Shibata K, Koshimizu TA.
    • Journal Title

      Eur J Pharmacol.

      Volume: 765 Pages: 291-299

    • DOI

      10.1016/j.ejphar.2015.08.043

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Journal Article] Pharmacological lineage analysis revealed the binding affinity of broad-spectrum substance P antagonists to receptors for gonadotropin-releasing peptide2015

    • Author(s)
      Arai K, Kashiwazaki A, Fujiwara Y, Tsuchiya H, Sakai N, Shibata K, Koshimizu TA3
    • Journal Title

      Eur J Pharmacol

      Volume: 749 Pages: 98-106

    • DOI

      10.1016/j.ejphar.2015.01.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590327, KAKENHI-PROJECT-24790259
  • [Journal Article] Identification of protein arginine N-methyltransferase 5 (PRMT5) as a novel interacting protein with the tumor suppressor protein RASSF1A.2015

    • Author(s)
      Sakai N, Saito Y, Fujiwara Y, Shiraki T, Imanishi Y, Koshimizu TA, Shibata K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 467 Issue: 4 Pages: 778-784

    • DOI

      10.1016/j.bbrc.2015.10.065

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Journal Article] α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs.2013

    • Author(s)
      Kumazaki M
    • Journal Title

      Eur J Pharmacol

      Volume: 705 Issue: 1-3 Pages: 1-10

    • DOI

      10.1016/j.ejphar.2013.02.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590504, KAKENHI-PROJECT-24590327
  • [Journal Article] α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs2013

    • Author(s)
      Kumazaki M, Ando H, Kakei M, Ushi j ima K, Taniguchi Y, Yoshida M, Yamato S, Washino S, Koshimizu TA, Fujimura A
    • Journal Title

      Eur J Pharmacol

      Volume: 705 Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590504
  • [Journal Article] Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts2013

    • Author(s)
      Yodo Tamaki, Yoshitaka Iwanaga (Corresponding Author), Shinichiro Niizuma, Tsuneaki Kawashima, Takao Kato, Yasutaka Inuzuka, Takahiro Horie, Hanako Morooka, Toru Takase, Yasumitsu Akahashi, Kazuhiro Kobuke, Koh Ono, Tetsuo Shioi, Soren P Sheikh, Noona Ambartsumian, Eugene Lukanidin, Taka-aki Koshimizu, Shunichi Miyazaki, Takeshi Kimura
    • Journal Title

      J Mol Cell Cardiol

      Volume: 57 Pages: 72-81

    • Data Source
      KAKENHI-PROJECT-22590815
  • [Journal Article] Serum amyloid A upsurge precedes standard biomarkers of hepatotoxicity in ritodrine-injected mice.2013

    • Author(s)
      Tsuchiya H, Sato J, Tsuda H, Fujiwara Y, Yamada T, Fujimura A, Koshimizu TA.
    • Journal Title

      Toxicology

      Volume: 305 Pages: 79-88

    • DOI

      10.1016/j.tox.2013.01.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Journal Article] Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts2013

    • Author(s)
      Tamaki Y, Iwanaga Y, Niizuma S, Kawashima T, Kato T, Inuzuka Y, Horie T, Morooka H, Takase T, Akahashi Y, Kobuke K, Ono K, Shioi T, Sheikh SP, Ambartsumian N, Lukanidin E, Koshimizu TA, Miyazaki S, Kimura T
    • Journal Title

      J Mol Cell Cardiol

      Volume: 57 Pages: 72-81

    • DOI

      10.1016/j.yjmcc.2013.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390211, KAKENHI-PROJECT-23659469, KAKENHI-PUBLICLY-24116512, KAKENHI-PROJECT-24590327, KAKENHI-PROJECT-24591094, KAKENHI-PROJECT-24790753, KAKENHI-PROJECT-24790790, KAKENHI-PUBLICLY-25136709, KAKENHI-PROJECT-25462136, KAKENHI-PROJECT-25670383
  • [Journal Article] Voluntary locomotion linked with cerebral activation is mediated by vasopressin V1a receptors in free-moving mice2012

    • Author(s)
      Masuki S, Sumiyoshi E, Koshimizu T, Qian J, Higuchi K, Tsujimoto G, and Nose H
    • Journal Title

      J Physiol (Lond.)

      Volume: (in press) Issue: 14 Pages: 3651-3665

    • DOI

      10.1113/jphysiol.2013.251876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659121, KAKENHI-PROJECT-24590327, KAKENHI-PROJECT-24689014
  • [Journal Article] The roles of V1a vasopressin receptors in blood pressure homeostasis : a review of studies on V1a receptor knockout mice2012

    • Author(s)
      Fujiwara Y, et.al.
    • Journal Title

      Clinical and experimental nephrology

      Volume: 16 Issue: 1 Pages: 30-34

    • DOI

      10.1007/s10157-011-0497-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590289, KAKENHI-PROJECT-24590327
  • [Journal Article] Vasopressin V1a and V1b receptors: from molecules to physiological systems2012

    • Author(s)
      T.A. Koshimizu, K. Nakamura, N. Egashira, M. Hiroyama, H. Nonoguchi, A. Tanoue
    • Journal Title

      Physiological reviews

      Volume: 92 Issue: 4 Pages: 1813-1864

    • DOI

      10.1152/physrev.00035.2011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590327, KAKENHI-PROJECT-24591244
  • [Journal Article] Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human2012

    • Author(s)
      Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Korner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Levy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, and Froguel P.
    • Journal Title

      Nature

      Volume: 483 Pages: 350-354

    • NAID

      120003874259

    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human2012

    • Author(s)
      Ichimura A
    • Journal Title

      Nature

      Volume: 483 Issue: 7389 Pages: 350-354

    • DOI

      10.1038/nature10798

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117008, KAKENHI-PROJECT-21390021, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-23890019, KAKENHI-PROJECT-24590327
  • [Journal Article] Chronic ritodrine treatment induces refractoriness of glucose-lowering beta2 adrenoceptor signal in female mice2012

    • Author(s)
      Tsuchiya H., et.al.
    • Journal Title

      Regulatory toxicology and pharmacology

      Volume: 62 Issue: 3 Pages: 561-567

    • DOI

      10.1016/j.yrtph.2011.11.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590289, KAKENHI-PROJECT-24590327
  • [Journal Article] The roles of V1a vasopressin receptors in blood pressure homeostasis : a review of studies on V1a receptor knockout mice2012

    • Author(s)
      Fujiwara Y, Tanoue A, Tsujimoto G, and Koshimizu TA.
    • Journal Title

      Clin Exp Nephrol

      Volume: 16 Pages: 30-34

    • NAID

      10030342354

    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] Protective Effect of .ALPHA.-Lipoic Acid Against Arsenic Trioxide-Induced Acute Cardiac Toxicity in Rats2011

    • Author(s)
      Kumazaki M, Ando H, Sasaki A, Koshimizu TA, Ushijima K, Hosohata K, Oshima Y, Fujimura A
    • Journal Title

      J Pharmacol Sci

      Volume: 115 Issue: 2 Pages: 244-248

    • DOI

      10.1254/jphs.10280SC

    • NAID

      10029892273

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590504
  • [Journal Article] Inhibition of heat shock protein 90 attenuates adenylate cyclase sensitization after chronic morphine treatment.2010

    • Author(s)
      Koshimizu T, et al.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 392(4) Pages: 603-607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] Inhibition of heat shock protein 90 attenuates adenylate cyclase sensitization after chronic morphine treatment.2010

    • Author(s)
      Koshimizu TA, Tsuchiya H, Tsuda H, Fujiwara Y, Shibata K, Hirasawa A, Tsujimoto G, Fujimura A.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 392 Pages: 603-607

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Oxytocin stimulates expression of a noncoding RNA tumor marker in a human neuroblastoma cell line.2010

    • Author(s)
      Koshimizu T, et al.
    • Journal Title

      Life Sciences

      Volume: 86 Pages: 455-460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] New topics in vasopressin receptors and approach to novel drugs : vasopressin and pain perception.2009

    • Author(s)
      Koshimizu T., et. al.
    • Journal Title

      J Pharmacol Sci. 109

      Pages: 33-37

    • NAID

      10025733430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659060
  • [Journal Article] Vasopressin regulation of blood pressure and volume : findings from V1a receptor-deficient mice2009

    • Author(s)
      Aoyagi, T., Koshimizu, T., et.al.
    • Journal Title

      Kidney International 76

      Pages: 1035-1039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFAR1; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu TA, Tsujimoto G.
    • Journal Title

      Biochem Biophys Res Commun. 365

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Production and characterization of a monoclonal antibody against GPR40 (FFARl ; free fatty acid receptor 1).2008

    • Author(s)
      Hirasawa A, Itsubo C, Sadakane K, Hara T, Shinagawa S, Koga H, Nose H, Koshimizu TA, Tsujimoto G.
    • Journal Title

      Biochei Biophys Res Commun. 365

      Pages: 22-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Cloning and characterization of the rat free fatty acid receptor GPR120 : in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.2008

    • Author(s)
      Tanaka T, Yano T, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 377

      Pages: 515-522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2008

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schiiedebergs Arch Pharmacol. 377

      Pages: 523-527

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Glucocorticoid-induced granzyme A expression can be used as a marker of glucocorticoid sensitivity for acutelymphoblastic leukemia therapy2007

    • Author(s)
      Myoumoto A, Nakatani K, Koshimizu TA, Matsubara H, Adachi S, Tsujimoto G.
    • Journal Title

      J. Hum. Genet. 52

      Pages: 328-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19109001
  • [Journal Article] Free fatty acids induce cholecystokinin secretion through GPR120.2007

    • Author(s)
      Tanaka T, Katsuma S, Adachi T, Koshimizu TA, Hirasawa A, Tsujimoto G.
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Glucocorticoid-induced granzyme A expression can be used as a marker of glucocorticoid sensitivity for acute2007

    • Author(s)
      Myoumoto A, Nakatani K, Koshimizu TA, Matsubara H, Adachi S,
    • Journal Title

      J. Hum. Genet.

      Pages: 328-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18018024
  • [Journal Article] 臨床ゲノム研究推進のためのDNAチップ技術2007

    • Author(s)
      輿水崇鏡、辻本豪三
    • Journal Title

      Bio Clinica 22

      Pages: 51-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18018024
  • [Journal Article] Carboxyl-terminal splicing enhances physical interactions between the cytoplasmic tails of purinergic P2X receptors.2006

    • Author(s)
      Koshimizu, T, Kretschmannova, K, He, ML, Ueno, S, Tanoue, A, Yanagihara, N, Stojilkovic, SS, Tsujimoto, G.
    • Journal Title

      Mol Pharmacol 69(5)

      Pages: 1588-98

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi, T, Tanaka, T, Takemoto, K, Koshimizu, T, Hirasawa, A, Tsujimoto, G.
    • Journal Title

      Biochem Biophys Res Commun 340(1)

      Pages: 332-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu TA, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem Biophys Res Commun. 340

      Pages: 332-337

    • Data Source
      KAKENHI-PROJECT-18052009
  • [Journal Article] Carboxy-terminal Splicing Enhances Physical Interactions between the Cytoplasmic Tails of Purinergic P2X Receptors.2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Mol Pharmacol (印刷中)

    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Proc Natl Acad Sci USA 103(20)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] V1a vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu, T, Nasa, Y, Tanoue, A, Oikawa, R, Kawahara, Y, Kiyono, Y, Adachi, T, Tanaka, T, Kuwaki, T, Mori, T, Takeo, S, Okamura, H, Tsujimoto, G.
    • Journal Title

      Proc Natl Acad Sci USA 103(20)

      Pages: 7807-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Carboxy-terminal Splicing Enhances Physical Interactions between the Cytoplasmic Tails of Purinergic P2X Receptors.2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Mol Pharmacol 69(5)

      Pages: 1588-1598

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] From the cover : V1a Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu TA, Nasa Y, Tanoue A, Oikawa R, Kawahara Y, Kiyono Y, Adachi T, Tanaka T, Kuwaki T, Mori T, Takeo S, Okamura H, Tsujimoto G
    • Journal Title

      Proc. Natl. Acad. Sci. U S A. Vol.103

      Pages: 7807-7812

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Proc Natl Acad Sci U S A 103(20)

      Pages: 1207-1207

    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem. Biophys. Res. Commun. 340

      Pages: 332-337

    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Functional Role of Spliced Cytoplasmic Tails in P2X(2)-Receptor- Mediated Cellular Signaling.2006

    • Author(s)
      Koshimizu, T, Tsujimoto, G.
    • Journal Title

      J Pharmacol Sci 101(4)

      Pages: 261-6

    • NAID

      130000074469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] From the cover Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu TA, Nasa Y, Tanoue A, Oikawa R, Kawahara Y, Kiyono Y, Adachi T, Tanaka T, Kuwaki T, Mori T, Takeo S, Okamura H, Tsujimoto G
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 103

      Pages: 7807-7812

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Functional Role of Spliced Cytoplasmic Tails in P2X(2)-Receptor-Mediated Cellular Signaling2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      J Pharmacol Sci 101(4)

      Pages: 261-266

    • NAID

      130000074469

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Proc Natl Acad Sci USA (印刷中)

    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Clinical implications from studies of alpha1 adrenergic receptor knockout mice.2006

    • Author(s)
      Koshimizu, T, Tanoue, A, Tsujimoto, G.
    • Journal Title

      Biochem Pharmacol. (accepted)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] From the cover : Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.2006

    • Author(s)
      Koshimizu TA, Nasa Y, Tanoue A, Oikawa R, Kawahara Y, Kiyono Y, Adachi T, Tanaka T, Kuwaki T, Mori T, Takeo S, Okamura H, Tsujimoto G.
    • Journal Title

      Proc. Natl. Acad. Sci. U S A. 103

      Pages: 7807-7812

    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G.
    • Journal Title

      Biochem. Biophys. Res. Commun. Vol.340

      Pages: 332-337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Free fatty acids administered into the colon promotes the secretion of glucagon-like peptide-1 and insulin.2006

    • Author(s)
      Adachi T, Tanaka T, Takemoto K, Koshimizu T, Hirasawa A, Tsujimoto G
    • Journal Title

      Biochem. Biophys. Res. Commun. 340

      Pages: 332-337

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation2005

    • Author(s)
      Hosoda C, Koshimizu T, et al.
    • Journal Title

      Molecular Pharmacology 67(3)

      Pages: 912-912

    • Data Source
      KAKENHI-PROJECT-15659063
  • [Journal Article] Correlation between vasoconstrictor roles and mRNA expression of alpha(1)-adrenoceptor subtypes in blood vessels of genetically engineered mice.2005

    • Author(s)
      Hosoda C, Tanoue A, Shibano M, Tanaka Y, Hiroyama M, Koshimizu TA, Cotecchia S, Kitamura T, Tsujimoto G, Koike K.
    • Journal Title

      Br. J. Pharmacol. Vol.146

      Pages: 456-466

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.2005

    • Author(s)
      Yamada M, Katsuma S, Adachi T, Hirasawa A, Shiojima S, Kadowaki T, Okuno Y, Koshimizu TA, Fujii S, Sekiya Y, Miyamoto Y, Tamura M, Yumura W, Nihei H, Kobayashi M, Tsujimoto G.
    • Journal Title

      Proc. Natl. Acad. Sci. U S A. Vol.102

      Pages: 7736-7741

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Inhibition of protein kinase CK2 prevents the progression of glomerulonephritis.2005

    • Author(s)
      Yamada M, Katsuma S, Adachi T, Hirasawa A, Shiojima S, Kadowaki T, Okuno Y, Koshimizu TA, Fujii S, Sekiya Y, Miyamoto Y, Tamura M, Yumura W, Nihei H, Kobayashi M, Tsujimoto G
    • Journal Title

      Proc. Natl. Acad. Sci. USA. 102

      Pages: 7736-7741

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Two alphal-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.2005

    • Author(s)
      Hosoda C, Koshimizu TA, Tanoue A, Nasa Y, Oikawa R, Tomabechi T, Fukuda S, Shinoura H, Oshikawa S, Takeo S, Kitamura T, Cotecchia S, Tsujimoto G
    • Journal Title

      Mol. Pharm. Vol.67

      Pages: 912-922

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Two alphal-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.2005

    • Author(s)
      Hosoda C, Koshimizu TA, Tanoue A, Nasa Y, Oikawa R, Tomabechi T, Fukuda S, Shinoura H, Oshikawa S, Takeo S, Kitamura T, Cotecchia S, Tsujimoto G
    • Journal Title

      Mol. Pharm. 67

      Pages: 912-922

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Correlation between vasoconstrictor roles and mRNA expression of alpha(1)-adrenoceptor subtypes in blood vessels of genetically engineered mice.2005

    • Author(s)
      Hosoda C, Tanoue A, Shibano M, Tanaka Y, Hiroyama M, Koshimizu TA, Cotecchia S, Kitamura T, Tsujimoto G, Koike K
    • Journal Title

      Br. J. Pharmacol. 146

      Pages: 456-466

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17209003
  • [Journal Article] Two alphal-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation.2005

    • Author(s)
      Hosoda, C., Koshimizu T.et al.
    • Journal Title

      Mol Pharmacol 67(3)

      Pages: 912-922

    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Identification of ectodomain regions contributing to gating, deactivation, and resensitization of purinergic P2X receptors2004

    • Author(s)
      Zemkova H, Koshimizu T et al.
    • Journal Title

      Journal Neuroscience 24(3)

      Pages: 6968-6968

    • Data Source
      KAKENHI-PROJECT-15659063
  • [Journal Article] Heterogeneity of G protein-coupled receptor generated by post-translational mechanisms and its clinical meanings.2004

    • Author(s)
      Tanoue A, Koshimizu T, et al.
    • Journal Title

      Nippon Yakurigaku Zasshi 124(4)

      Pages: 235-235

    • NAID

      130000088789

    • Data Source
      KAKENHI-PROJECT-15659063
  • [Journal Article] Carvedilol selectively inhibits oscillatory intracellular calcium changes evoked by human alpha1D- and alpha1B-adrenergic receptors.2004

    • Author(s)
      Koshimizu T, Tsujimoto G et al.
    • Journal Title

      Cardiovascular Research 63(3)

      Pages: 662-662

    • Data Source
      KAKENHI-PROJECT-15659063
  • [Journal Article] Intracellular calcium measurements as a method in studies on activity of purinergic P2X receptor channels2003

    • Author(s)
      Zemkova H, Koshimizu T
    • Journal Title

      American Journal of Physiology and Cell Physiology 285(2)

      Pages: 235-235

    • Data Source
      KAKENHI-PROJECT-15659063
  • [Journal Article] Clinical implications from studies of alphal adrenergic receptor knockout mice

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Biochem Pharmacol (accepted)

    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Clinical implications from studies of alphal adrenergic receptor knockout mice

    • Author(s)
      Koshimizu T., et al.
    • Journal Title

      Biochem Pharmacol (accepted)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590058
  • [Journal Article] Vla Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.

    • Author(s)
      Koshimizu T
    • Journal Title

      Proc.Natl.Acad.Sci.USA. (印刷中)

    • Data Source
      KAKENHI-PROJECT-17019038
  • [Journal Article] V1a Vasopressin receptors maintain normal blood pressure by regulating circulating blood volume and baroreflex sensitivity.

    • Author(s)
      Koshimizu T
    • Journal Title

      Proc.Natl.Acad.Sci.USA. (印刷中)

    • Data Source
      KAKENHI-PROJECT-17209003
  • [Presentation] オピオイド鎮痛耐性におけるV1bバゾプレッシン受容体複合体の機能解析2020

    • Author(s)
      輿水崇鏡、Chortip S、Fujianti C、Nuttawadee N、藤原葉子、 東森生、土屋裕義、谷口淳一
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] ラット下垂体前葉の内分泌細胞は基底膜成分ラミニンα3鎖およびα5鎖に反応する2020

    • Author(s)
      東 森生、輿水 崇鏡
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] ラット下垂体前葉の内分泌細胞が接する基底膜を構成するラミニン分子の役割2019

    • Author(s)
      東 森生、輿水崇鏡
    • Organizer
      第141回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] V1bバゾプレッシン受容体高次複合体によるオピオイド鎮痛の調節2018

    • Author(s)
      Koshimizu TA et. al.
    • Organizer
      第139回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] マシンインテリジェンスによるバゾプレシン受容体欠損マウスの表現型解析2018

    • Author(s)
      輿水崇鏡、Chortip S、Fujianti C、Nuttawadee N、藤原葉子、 東森生、土屋裕義、谷口淳一
    • Organizer
      第29回バソプレシン研究会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] バゾプレシン研究最前線:受容体データサイエンスからの期待と展望2018

    • Author(s)
      輿水崇鏡
    • Organizer
      東京腎生理研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] 痛みに関わるV1bバゾプレッシン受容体高次複合体の機能解析2018

    • Author(s)
      輿水崇鏡、Nuttawadee Ngamlertwong、藤原葉子、土屋裕義、谷口淳一
    • Organizer
      バゾプレッシン研究会
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Analysis of interaction between dimerized receptor and receptor-interacting protein2018

    • Author(s)
      Koshimizu TA et. al.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] 痛みに関わるV1bバゾプレッシン受容体高次複合体の機能解析2018

    • Author(s)
      輿水崇鏡、Nuttawadee Ngamlertwong、藤原葉子、土屋裕義、谷口淳一
    • Organizer
      バゾプレッシン研究会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] バゾプレッシンV1b受容体の痛覚における新知見と応用2017

    • Author(s)
      輿水崇鏡
    • Organizer
      氷川フォーラム
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] Regulation of morphine sensitivity and adenylate cyclase sensitization by carboxyl-terminus of V1b vasopressin receptors2017

    • Author(s)
      Taka-aki Koshimizu, Kenji Honda, and Yukio Takano
    • Organizer
      International Narcotics Research Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] Zwitterionic Polymers for Peptide Hormone Delivery to the Intracellular G-Protein Coupled Receptors2017

    • Author(s)
      Aki Kashiwazaki, Taka-aki Kashimizu, Masaru Tanaka
    • Organizer
      Biomaterials International 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] 分子系統樹を用いた、オーファンGタンパク質共役型受容体の機能予測2017

    • Author(s)
      笹井隆太郎、宮崎葵、輿水崇鏡
    • Organizer
      自治医大シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] Comparative analysis of vasopressin V1a receptor distribution in rodent and human kidneys2017

    • Author(s)
      Torsten Giesecke, Taka-aki Koshimizu et al.
    • Organizer
      Kidney week 2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] マウス視床下部神経細胞の突起形成へのプロスタグランジンD2 の作用2017

    • Author(s)
      土屋裕義、北條寛典、杉本幸彦、Ngamlertwong Nuttawadee、藤原葉子、輿水崇鏡
    • Organizer
      日本下垂体研究会学術集会
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] バゾプレッシン受容体高次複合体の基礎と臨床2017

    • Author(s)
      輿水崇鏡
    • Organizer
      薬師寺人セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] Regulation of morphine sensitivity and adenylate cyclase sensitization by carboxyl-terminus of V1b vasopressin receptors2017

    • Author(s)
      Taka-aki Koshimizu1, Kenji Honda, and Yukio Takano
    • Organizer
      International Narcotics Research Conference2017 meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Comparative analysis of vasopressin V1a receptor distribution in rodent and human kidneys2017

    • Author(s)
      Torsten Giesecke, Taka-aki Koshimizu, et al.
    • Organizer
      2017 Kidney Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04323
  • [Presentation] 分子系統樹を用いた、オーファンGタンパク質共役型受容体の機能予測2017

    • Author(s)
      笹井隆太郎、宮崎葵、輿水崇鏡
    • Organizer
      自治医大シンポジウム
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Deficits in Female Reproductive Function in V1a Vasopressin Receptor Knockout Mice2016

    • Author(s)
      Hiroyoshi Tsuchiya, Shyota Fujimura, Akio Fujimura, Yoko Fujiwara, Taka-aki Koshimizu
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Extracellular sodium ion is essential for internalization of vasopressin V1B receptors2016

    • Author(s)
      Taka-aki Koshimizu, Aki Kashiwazaki, Yoko Fujiwara, Hiroyoshi Tsuchiya and Junichi Taniguchi
    • Organizer
      International Symposium on Pituitary Gland and Related Systems
    • Place of Presentation
      Hawaii Imin International Conference Center (USA)
    • Year and Date
      2016-09-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Cellular localization and sodium ion sensitivity of Vasopressin V1b receptors2016

    • Author(s)
      Taka-aki Koshimizu, Aki Kashiwazaki, Yoko Fujiwara, Hiroyoshi Tsuchiya and Junichi Taniguchi
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] Gタンパク質共役型受容体内在化における外液イオン感受性の新知見2016

    • Author(s)
      輿水崇鏡、柏崎亜樹、谷口淳一
    • Organizer
      第134回日本薬理学会関東部会
    • Place of Presentation
      国際医療福祉大学(栃木県・大田原市)
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] V1bバゾプレッシン受容体複合体の機能解析2015

    • Author(s)
      輿水崇鏡、本多健治、高野行夫
    • Organizer
      バゾプレッシン研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-01-10
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] バゾプレッシンV1b受容体の新知見と応用2015

    • Author(s)
      輿水崇鏡
    • Organizer
      日本下垂体研究会
    • Place of Presentation
      富山
    • Year and Date
      2015-08-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K15055
  • [Presentation] 下垂体後葉ホルモンによるアデニレートサイクラーゼシグナルの調節機構2014

    • Author(s)
      輿水崇鏡
    • Organizer
      第14回バゾプレッシン研究会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] V1bバゾプレッシン受容体内在化機構の解明と制御2014

    • Author(s)
      柏﨑亜樹、藤原葉子、土屋裕義、輿水崇鏡
    • Organizer
      第130回日本薬理学会関東部会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-05
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] Functional Interaction between V1b Vasopressin and MOR1 Opioid Receptors Delays Development of Morphine Tolerance and Adenylate Cyclase Sensitization2014

    • Author(s)
      Taka-aki Koshimizu, Kenji Honda, Yukio Takano
    • Organizer
      第87回日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] オピオイド鎮痛におけるバゾプレッシンの役割について2013

    • Author(s)
      輿水崇鏡、本多健治、高野行夫
    • Organizer
      第23回バゾプレッシン研究会
    • Place of Presentation
      慶応義塾大学
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] 合成サブスタンスPアンタゴニストの広域性とシグナル制御機構2012

    • Author(s)
      荒井和音、輿水崇鏡
    • Organizer
      第126回日本薬理学会関東部会
    • Place of Presentation
      北里大学
    • Data Source
      KAKENHI-PROJECT-24590327
  • [Presentation] 広域性神経ペプチドアンクゴニストによるバプレッシン受容体シグナルの制御機構2011

    • Author(s)
      輿水崇鏡
    • Organizer
      日本神経内分泌学会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Presentation] Inhibition of heat shock protein 90 attenuates adenylate cyclase sensitization after chronic morphine treatment2010

    • Author(s)
      Koshimizu, et al.
    • Organizer
      16th World Congress of Basic and Clinical Pharmacology
    • Place of Presentation
      ベルギー コペンハーゲン
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Presentation] 脂肪酸受容体GPR120の代謝調節機構の解析2010

    • Author(s)
      平澤明、原貴史、市村敦彦、宮内諭、木村郁夫、輿水崇鏡、辻本豪三
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21390021
  • [Presentation] モルヒネ依存モデル細胞におけるCREB結合部位の解析2009

    • Author(s)
      輿水崇鏡, 辻本豪三
    • Organizer
      第82回日本薬理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-19659060
  • [Presentation] Critical roles of V1a and V1b vasopressin receptors in systemic blood pressure Homeostasis : studies from gene knockout mice2009

    • Author(s)
      Koshimizu T, et.al.
    • Organizer
      Mechanisms of Vasodilatation Conference
    • Place of Presentation
      ホテル松島大観荘(宮城県)
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-21590289
  • [Presentation] バゾプレッシン受容体を標的分子としたゲノム創薬研究2008

    • Author(s)
      輿水 崇鏡、辻本 豪三
    • Organizer
      第81回日本薬理学会
    • Place of Presentation
      パシフィコ横浜 会議センター
    • Year and Date
      2008-03-18
    • Data Source
      KAKENHI-PROJECT-19659060
  • [Presentation] 遊離脂肪酸受容体における特異的抗体の作成と祖織分布の解析2007

    • Author(s)
      宮内諭, 平澤明, 井坪千怜, 輿水崇鏡, 定金惠子, 原貴史, 辻本豪三
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 新規遊離脂肪酸受容体GPR40およびGPR120のリガンド結合様式の検討2007

    • Author(s)
      和田浩志, 平澤明, 定金恵子, 矢野武明, 原貴史, 嶽本和久, 足達哲也, 輿水崇鏡, 石黒正路, 辻本豪三
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18052009
  • [Presentation] 長鎖脂肪酸のGPR120を介したアディポネクチン分泌促進作用2007

    • Author(s)
      伊賀朋世, 足達哲也, 輿水 崇鏡, 平澤 明, 辻本豪三
    • Organizer
      第17回日本循環薬理学会
    • Place of Presentation
      大阪大学医学部
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-18052009
  • 1.  HIRASAWA Akira (70242633)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 16 results
  • 2.  TSUJIMOTO Gozoh (80172013)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 19 results
  • 3.  ADACHI Tetsuya (60345014)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 16 results
  • 4.  OKUNO Yasushi (20283666)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  TSUCHIYA Hiroyoshi (80508755)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  FUJIMURA Akio (90156901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  SHIBATA Katsushi (70296565)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SHIRAKI Takashi (10294208)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  SAKAI Nobuya (30525077)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  IMANISHI Yorihisa (80255538)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  AWAJI Takeo (60297546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  LIU Ning (70464196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IIDA Keiko (00422999)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KUMASAKI Msafumi (50547966)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IWANAGA Yoshitaka (80360816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  ONO Koh (00359275)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  ANDO Hitoshi (50382875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KAKEI Masafumi (90214270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIGA Tsuyoshi (00277211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  田上 昭人 (60301800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 21.  三輪 嘉尚 (20093320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  松本 治 (10231599)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  木村 郁夫 (80433689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  寺澤 和哉 (00361569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  門脇 正史 (30378864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  東 森生 (90709643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 27.  HORIE Takahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  能勢 博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi