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Taguchi Keiko  田口 恵子

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TAGUCHI Keiko  田口 恵子

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Researcher Number 20466527
Other IDs
Affiliation (Current) 2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help 2023: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
2019 – 2023: 東北大学, 医学系研究科, 准教授
2017 – 2019: 東北大学, 医学系研究科, 講師
2015 – 2016: 東北大学, 医学系研究科, 助教
2015: 東北大学, 医学(系)研究科(研究院), 助教 … More
2013 – 2014: 東北大学, 加齢医学研究所, 助教
2012: 東北大学, 医学(系)研究科(研究院), 助教
2010 – 2011: 東北大学, 大学院・医学系研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Biological Sciences / Basic Section 49010:Pathological biochemistry-related / Environmental pharmacy
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Medium-sized Section 48:Biomedical structure and function and related fields / Broad Section H / Gastroenterology
Keywords
Principal Investigator
Nrf2 / 肝臓 / 転写因子 / がん / Keap1 / オートファジー / 肝臓がん / 遺伝子改変ラット / 食道がん / 細胞競合 … More / 食道 / 腫瘍 / 化学発がん / 肝腫瘍 / 肝がん / 肝肥大 / 門脈枝結紮 / 増殖 / Aktシグナル / 肝疾患 / 翻訳後修飾 / Akt / タンパク質分解 / 蛋白質分解 … More
Except Principal Investigator
酸化ストレス / Keap1 / Nrf2 / 活性硫黄 / 活性イオウ / 膵癌 / KEAP1-NRF2系 / 健康長寿 / 加齢関連疾患 / Keap1-Nrf2制御系 / ストレス応答 / 膵癌モデルマウス / KPCマウス / 遺伝子 / ストレス / 環境 / 発現制御 / エリスロポエチン / 低酸素 / 環境応答 Less
  • Research Projects

    (15 results)
  • Research Products

    (281 results)
  • Co-Researchers

    (20 People)
  •  肝臓の組織構築におけるNrf2の新たな機能Principal Investigator

    • Principal Investigator
      田口 恵子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      The University of Tokyo
      Tohoku University
  •  硫黄生物学から紐解く膵癌難治化機構の解明と治療応用

    • Principal Investigator
      正宗 淳
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Development of esophagus cancer acquired Nrf2 activationPrincipal Investigator

    • Principal Investigator
      TAGUCHI Keiko
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Tohoku University
  •  Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section H
    • Research Institution
      Tohoku University
  •  生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Development of novel therapy for pancreatic cancer based on the regulation of oxidative stress responses

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Hepatic tumor and Nrf2 activation by impaired autophagy(Fostering Joint International Research)Principal Investigator

    • Principal Investigator
      Taguchi Keiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略Principal Investigator

    • Principal Investigator
      田口 恵子
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Role of oxidative stress response in pancreatic diseases and therapeutic application

    • Principal Investigator
      Masamune Atsushi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Hepatic tumor and Nrf2 activation by impaired autophagyPrincipal Investigator

    • Principal Investigator
      Taguchi Keiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  肝疾患における転写因子Nrf2の機能変化Principal Investigator

    • Principal Investigator
      田口 恵子
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Role of Nrf2 in compensatory liver proliferation after portal vein branch ligation in micePrincipal Investigator

    • Principal Investigator
      TAGUHI Keiko
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Keap1-Nrf2システムとAktシグナルの相互作用と肝疾患Principal Investigator

    • Principal Investigator
      田口 恵子
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Pathogenesis by disrupting the cytoprotective systemPrincipal Investigator

    • Principal Investigator
      TAGUCHI Keiko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Tohoku University
  •  Molecular Mechanisms of Adaptive Responses to Food and Oxygen

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tohoku University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Other

  • [Book] Protein modifications in pathogenic dysregulation of signaling2015

    • Author(s)
      Taguchi K, Yamamoto M
    • Publisher
      Springer
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Book] Protein modifications in pathogenic dysregulation of signaling, Chapter 17 Keap1-Nrf2 regulatory system and cancer2015

    • Author(s)
      Taguchi K, Yamamoto M
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Book] Protein modifications in pathogenic dysregulation of signaling2015

    • Author(s)
      Taguchi K, Yamamoto M
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Book] 毒性の科学―分子・細胞から人間集団まで2014

    • Author(s)
      1. 田口恵子
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Book] 「毒性の科学―分子・細胞から人間集団まで」第2章3節Keap1-Nrf2システムと毒物の解毒・排泄2014

    • Author(s)
      田口恵子
    • Total Pages
      200
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Book] 毒性の科学一分子、細胞から人間集団まで、第2章3節Keap1 - Nrf2システムと毒物の解毒・排泄2014

    • Author(s)
      田口恵子
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Book] 「毒性の科学―分子・細胞から人間集団まで」第2章3節Keap1-Nrf2システムと毒物の解毒・排泄2014

    • Author(s)
      田口恵子
    • Total Pages
      200
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Book] 酸化ストレスの医学改訂第2版2014

    • Author(s)
      田口恵子、山本雅之
    • Total Pages
      444
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Book] 酸化ストレスの医学改訂第2版2014

    • Author(s)
      2. 田口恵子、山本雅之
    • Total Pages
      444
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Book] 第2章3節Keap1-Nrf2システムと毒物の解毒・排泄、「毒性の科学―分子・細胞から人間集団まで」2013

    • Author(s)
      田口恵子
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Book] 第2章3節Keap1-Nrf2システムと毒物の解毒・排泄、「毒性の科学―分子・細胞から人間集団まで」2013

    • Author(s)
      田口恵子
    • Publisher
      東京大学出版会
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Book] 活性酸素種や親電子性物質によるシグナル伝達実験医学2012増刊号「シグナル伝達研究の最前線 2012-2013」2012

    • Author(s)
      田口恵子、山本雅之
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Book] 第3章6節「代謝リプログラミングにおける酸化ストレス応答機構の役割」、活性酸素・ガス状分子による恒常性制御と疾患、『実験医学』2012増刊号2012

    • Author(s)
      田口恵子、本橋ほづみ
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Book] 第3章6節「代謝リプログラミングにおける酸化ストレス応答機構の役割」、活性酸素・ガス状分子による恒常性制御と疾患、『実験医学』2012増刊号2012

    • Author(s)
      田口恵子、本橋ほづみ
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Book] 第2章7節「活性酸素種や親電子性物質によるシグナル伝達」、シグナル伝達研究の最前線 2012-2013 『実験医学』2012増刊号2012

    • Author(s)
      田口恵子、山本雅之
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Book] 実験医学2012増刊号「シグナル伝達研究の最前線2012-2013」7.活性酸素種や親電子性物質によるシグナル伝達2012

    • Author(s)
      田口恵子、山本雅之
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Book] 第2章7節「活性酸素種や親電子性物質によるシグナル伝達」、シグナル伝達研究の最前線 2012-2013 『実験医学』2012増刊号2012

    • Author(s)
      田口恵子、山本雅之
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Book] 実験医学2012増刊号「シグナル伝達研究の最前線2012-2013」7.活性酸素種や親電子性物質によるシグナル伝達2012

    • Author(s)
      田口恵子、山本雅之
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Journal Article] Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes2023

    • Author(s)
      Kowalik Marta A., Taguchi Keiko, Serra Marina, Caddeo Andrea, Puliga Elisabetta, Bacci Marina, Koshiba Seizo, Inoue Jin, Hishinuma Eiji, Morandi Andrea, Giordano Silvia, Perra Andrea, Yamamoto Masayuki, Columbano Amedeo
    • Journal Title

      Hepatology

      Volume: 79 Issue: 4 Pages: 829-843

    • DOI

      10.1097/hep.0000000000000568

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06906
  • [Journal Article] A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells2023

    • Author(s)
      Baird Liam、Taguchi Keiko、Zhang Anqi、Takahashi Yushi、Suzuki Takafumi、Kensler Thomas W.、Yamamoto Masayuki
    • Journal Title

      Redox Biology

      Volume: 66 Pages: 102845-102845

    • DOI

      10.1016/j.redox.2023.102845

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice2023

    • Author(s)
      Shimizu Ritsuko、Hirano Ikuo、Hasegawa Atsushi、Suzuki Mikiko、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Uruno Akira、Suzuki Norio、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 875-875

    • DOI

      10.1038/s42003-023-05251-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
  • [Journal Article] Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals2023

    • Author(s)
      Aoki YI, Taguchi K, Anzawa H, Kawashima J, Ishida N, Otuki A, Hasegawa A, Baird L, Suzuki T, Motoike IN, Ohneda K, Kumada K, Katsuoka F, Kinoshita K, Yamamoto M.
    • Journal Title

      J Biochem

      Volume: Online ahead of print. Issue: 6 Pages: 611-627

    • DOI

      10.1093/jb/mvae008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
  • [Journal Article] Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium2023

    • Author(s)
      Hirose Wataru、Horiuchi Makoto、Li Donghan、Motoike Ikuko N.、Zhang Lin、Nishi Hafumi、Taniyama Yusuke、Kamei Takashi、Suzuki Mikiko、Kinoshita Kengo、Katsuoka Fumiki、Taguchi Keiko、Yamamoto Masayuki
    • Journal Title

      Cellular and Molecular Gastroenterology and Hepatology

      Volume: 15 Issue: 1 Pages: 153-178

    • DOI

      10.1016/j.jcmgh.2022.09.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-21K16466, KAKENHI-PROJECT-19H05649
  • [Journal Article] The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation <i>In Vivo</i>2022

    • Author(s)
      Kuga Ayumi、Tsuchida Kouhei、Panda Harit、Horiuchi Makoto、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Suzuki Mikiko、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 42 Issue: 7 Pages: 1-22

    • DOI

      10.1128/mcb.00563-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening2022

    • Author(s)
      Wakamori Shun、Taguchi Keiko、Nakayama Yuki、Ohkoshi Akira、Sporn Michael B.、Ogawa Takenori、Katori Yukio、Yamamoto Masayuki
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 188 Pages: 206-220

    • DOI

      10.1016/j.freeradbiomed.2022.06.239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] The KEAP1-NRF2 system and esophageal cancer2022

    • Author(s)
      Hirose W, Oshikiri H, Taguchi K, Yamamoto M
    • Journal Title

      Cancers

      Volume: 14 Issue: 19 Pages: 4702-4702

    • DOI

      10.3390/cancers14194702

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
  • [Journal Article] AHR and NRF2 in Skin Homeostasis and Atopic Dermatitis2022

    • Author(s)
      Edamitsu T, Taguchi K, Okuyama R, Yamamoto M
    • Journal Title

      Antioxidants

      Volume: 11 Issue: 2 Pages: 227-227

    • DOI

      10.3390/antiox11020227

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition2021

    • Author(s)
      Hamada S, Matsumoto R, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      Int J Mol Sci.

      Volume: 22 Issue: 4 Pages: 1870-1870

    • DOI

      10.3390/ijms22041870

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08300, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03631
  • [Journal Article] Nrf2 expression in pancreatic stellate cells promotes progression of cancer.2021

    • Author(s)
      Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 321 Issue: 4 Pages: G378-G388

    • DOI

      10.1152/ajpgi.00120.2021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] Nuclear factor erythroid 2-related factor 2 depletion sensitizes pancreatic cancer cells to gemcitabine via aldehyde dehydrogenase 3a1 repression.2021

    • Author(s)
      Matsumoto R, Hamada S, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      J Pharmacol Exp Ther.

      Volume: 379 Issue: 1 Pages: 33-40

    • DOI

      10.1124/jpet.121.000744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] 環境応答・適応の分子機構2021

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      日本体質医学学会誌

      Volume: 83 Pages: 38-45

    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Journal Article] The KEAP1-NRF2 system as a molecular target of cancer treatment2021

    • Author(s)
      Taguchi K, Yamamoto M
    • Journal Title

      Cancers

      Volume: 13 Issue: 1 Pages: 46-46

    • DOI

      10.3390/cancers13010046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-16H06276
  • [Journal Article] Keap1-Nrf2システムによる生体機能制御機構の解明2020

    • Author(s)
      田口恵子
    • Journal Title

      東北醫學雑誌

      Volume: 132 Pages: 36-38

    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma.2020

    • Author(s)
      Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol.

      Volume: 318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03631
  • [Journal Article] Nrf2 in liver toxicology2020

    • Author(s)
      2.Taguchi K, Kensler TW
    • Journal Title

      Arch Pharmacal Res

      Volume: 43 Issue: 3 Pages: 337-349

    • DOI

      10.1007/s12272-019-01192-3

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma2020

    • Author(s)
      1.Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 318 Issue: 3 Pages: G419-G427

    • DOI

      10.1152/ajpgi.00296.2019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
  • [Journal Article] Cellular Nrf2 levels determine cell fate during chemical carcinogenesis in esophageal epithelium2020

    • Author(s)
      Horiuchi M, Taguchi K, Hirose W, Tsuchida K, Suzuki M, Taniyama Y, Kamei T, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 41 Issue: 2

    • DOI

      10.1128/mcb.00536-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649
  • [Journal Article] NRF2 in liver toxicology2019

    • Author(s)
      Keiko Taguchi, Thomas W. Kensler
    • Journal Title

      Archives of Pharmacal Research

      Volume: 印刷中

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Journal Article] Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma2018

    • Author(s)
      Hamada Shin、Shimosegawa Tooru、Taguchi Keiko、Nabeshima Tatsuhide、Yamamoto Masayuki、Masamune Atsushi
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 314 Issue: 1 Pages: G65-G74

    • DOI

      10.1152/ajpgi.00228.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis2018

    • Author(s)
      Orru Claudia、Szydlowska Marta、Taguchi Keiko、Zavattari Patrizia、Perra Andrea、Yamamoto Masayuki、Columbano Amedeo
    • Journal Title

      Journal of Hepatology

      Volume: 69 Issue: 3 Pages: 635-643

    • DOI

      10.1016/j.jhep.2018.05.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15KK0325
  • [Journal Article] The KEAP1-NRF2 system in cancer.2017

    • Author(s)
      Taguchi K, Yamamoto M.
    • Journal Title

      Frontiers in Oncology

      Volume: 7 Pages: 85-85

    • DOI

      10.3389/fonc.2017.00085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15KK0325, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis2017

    • Author(s)
      Hamada Shin、Taguchi Keiko、Masamune Atsushi、Yamamoto Masayuki、Shimosegawa Tooru
    • Journal Title

      Carcinogenesis

      Volume: 38 Issue: 6 Pages: 661-670

    • DOI

      10.1093/carcin/bgx043

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells.2016

    • Author(s)
      Shinkai Y, Kimura T, Itagaki A, Yamamoto C, Taguchi K, Yamamoto M, Kumagai Y, Kaji T.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 295 Pages: 37-46

    • DOI

      10.1016/j.taap.2016.01.020

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-15K14992, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-24390034, KAKENHI-PUBLICLY-16H01190, KAKENHI-PROJECT-15KK0325
  • [Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016

    • Author(s)
      Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
    • Journal Title

      Nature Commun

      Volume: 7 Issue: 1 Pages: 12030-12030

    • DOI

      10.1038/ncomms12030

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
  • [Journal Article] The transcription factor Bach2 is phosphorylated at multiple sites in murine B cells but a single site prevents its nuclear localization.2016

    • Author(s)
      Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K.
    • Journal Title

      J Biol Chem

      Volume: 291 Pages: 1826-1840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Journal Article] Generation of a new model rat: Nrf2 knockout rats are sensitive to aflatoxin B1 toxicity.2016

    • Author(s)
      Taguchi K, Takaku M, Egner PA, Morita M, Kaneko T, Mashimo T, Kensler TW, Yamamoto M.
    • Journal Title

      Toxicol Sci

      Volume: in press Issue: 1 Pages: 40-52

    • DOI

      10.1093/toxsci/kfw065

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460384, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26291005, KAKENHI-PROJECT-15KK0325, KAKENHI-INTERNATIONAL-15K21759
  • [Journal Article] Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.2015

    • Author(s)
      Kanamori M*, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H*, and Tominaga T.
    • Journal Title

      Neuro-Oncology

      Volume: 17 Issue: 4 Pages: 555-565

    • DOI

      10.1093/neuonc/nou282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670613, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26860180
  • [Journal Article] 肝疾患における転写因子Nrf2の機能変化2015

    • Author(s)
      田口恵子
    • Journal Title

      別冊BIO Clinica

      Volume: 4 Pages: 159-161

    • Data Source
      KAKENHI-PROJECT-26460384
  • [Journal Article] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.2014

    • Author(s)
      Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 34 Issue: 5 Pages: 900-913

    • DOI

      10.1128/mcb.01384-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22118006, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-24116508, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670187, KAKENHI-PROJECT-26460384
  • [Journal Article] The circadian clock regulates rhythmic activation of the NRF2/glutathione - mediated antioxidant defense pathway to modulate pulmonary fibrosis2014

    • Author(s)
      Pekovic, Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GT, Fukada Y, and Meng AJ.
    • Journal Title

      Genes Dev

      Volume: 28(6) Pages: 548-560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] The circadian clock regulates the NRF2/ARE-mediated antioxidant defence pathway in the mouse lung.2014

    • Author(s)
      Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GTJ, Fukada Y, and Meng Q-J.
    • Journal Title

      Genes Dev

      Volume: 28 Issue: 6 Pages: 548-560

    • DOI

      10.1101/gad.237081.113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112504, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25440041, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-24227001
  • [Journal Article] Nrf2 Enhances Cholangiocyte Expansion in Pten - Deficient Livers2014

    • Author(s)
      Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 34(5) Pages: 900-913

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Keapl inhibition attenuates glomerulosclerosis2014

    • Author(s)
      Miyazaki Y, Shimizu A, Pastan I, T Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29(4) Pages: 783-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Nrf2 Promotes Compensatory Liver Hypertrophy after Portal Vein Branch Ligation in Mice2014

    • Author(s)
      Shirasaki K, Taguchi K, Unno M, Motohashi H, Yamamoto M
    • Journal Title

      Hepatology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] 癌細胞のグルコース・グルタミン代謝異常と癌遺伝子異常はどのように関連づけられるか2014

    • Author(s)
      光石陽一郎、田口恵子
    • Journal Title

      分子消化器病

      Volume: 11

    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Journal Article] Nrf2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice.2014

    • Author(s)
      Shirasaki K, Taguchi K, Unno M, Motohashi H, and Yamamoto M
    • Journal Title

      Hepatology

      Volume: 59 Issue: 6 Pages: 2371-2382

    • DOI

      10.1002/hep.27020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150
  • [Journal Article] Keap1 inhibition attenuates glomerulosclerosis.2014

    • Author(s)
      Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Issue: 4 Pages: 783-791

    • DOI

      10.1093/ndt/gfu002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112502, KAKENHI-PUBLICLY-25117703, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26461241
  • [Journal Article] Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death2013

    • Author(s)
      Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T.
    • Journal Title

      J Neurochem

      Volume: 127 Issue: 5 Pages: 669-680

    • DOI

      10.1111/jnc.12325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592613, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703
  • [Journal Article] The role of the Nrf2 - mediated defense system in corneal epithelial wound healing2013

    • Author(s)
      Hayashi R, Himori N, Taguchi K, Ishikawa Y, Uesugi K, Ito M, Duncan T, Tsu j ikawa M, Nakazawa T, Yamamoto M, Nishida K
    • Journal Title

      Free Radic Biol Med

      Volume: 61C Pages: 333-342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] The role of the Nrf2-mediated defense system in corneal epithelial wound healing2013

    • Author(s)
      Hayashi R, Himori N, Taguchi K, Ishikawa Y, Uesugi K, Ito M, Duncan T, Tsujikawa M, Nakazawa T, Yamamoto M, Nishida K
    • Journal Title

      Free Radic Biol Med

      Volume: 61C Pages: 333-342

    • DOI

      10.1016/j.freeradbiomed.2013.04.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670731
  • [Journal Article] Critical role of Nrf2 in oxidative stress - induced retinal ganglion cell death2013

    • Author(s)
      Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T
    • Journal Title

      J Neurochem

      Volume: 127(5) Pages: 669-680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor.2012

    • Author(s)
      Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, Taguchi K, Ysuda M, Watanabe R, Takano J, Saido T, Minegishi N, Miyata T, Abe T, Yamamoto M.
    • Journal Title

      Neurobiological Disease

      Volume: 48 Issue: 3 Pages: 556-557

    • DOI

      10.1016/j.nbd.2012.07.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24700472, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
  • [Journal Article] 活性酸素・ガス状分子による恒常性制御と疾患、第3章6節代謝リプログラミングにおける酸化ストレス応答機構…の役割2012

    • Author(s)
      田口恵子、本橋ほづみ
    • Journal Title

      実験医学 (羊土社)

      Volume: 30(17) Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Metabolic stress response implicated in diabetic retinopathy : the role of calpain, and the therapeutic impact of calpain inhibitor2012

    • Author(s)
      Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, Taguchi K, Yasuda M, Watanabe R, Takano J, Takaomi S, Minegishi N, Miyata T, Abe T, Yamamoto M
    • Journal Title

      Neurobiol Dis

      Volume: 48(3) Pages: 556-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J Gastroenterol

      Volume: (in press)

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J.Gastroenterol

      Volume: (印刷中) Issue: 8 Pages: 924-935

    • DOI

      10.1007/s00535-012-0552-9

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-22500656, KAKENHI-PROJECT-22590802, KAKENHI-PROJECT-22790127, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Keap1 degradation by autophagy for the maintenance of redox homeostasis2012

    • Author(s)
      Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Issue: 34 Pages: 13561-13566

    • DOI

      10.1073/pnas.1121572109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Keapl degradation by autophagy for the maintenance of redox homeostasis2012

    • Author(s)
      Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 109(34) Pages: 13561-13566

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M, Motohashi H
    • Journal Title

      Cancer Cell

      Volume: 22(l) Pages: 66-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] シグナル伝達研究の最前線2012-2013第2章7節活性酸素種や親電子性物質によるシグナル伝達2012

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      実験医学 (羊土社)

      Volume: 30(5) Pages: 759-765

    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] 転写因子Nrf2はグルコースとグルタミンの代謝を変化させて代謝リプログラミングを促進する2012

    • Author(s)
      光石陽一郎、田口恵子、本橋ほづみ
    • Journal Title

      ライフサイエンス新着論文レビュー

    • URL

      http://first.1ifesciencedb.jp/archives/5262

    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Issue: 1 Pages: 66-79

    • DOI

      10.1016/j.ccr.2012.05.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M and Motohashi H
    • Journal Title

      Cancer Cell

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress - induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J Gastroenterol

      Volume: 47(8) Pages: 924-935

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011

    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes to Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Two-electron quinone reductase (AKR1C isozyme) augments the oxidative DNA damage induced by quinones in diesel exhaust particles by accelerating redox cycling2011

    • Author(s)
      Yamano S, Shibata M, Kita H, Matsusue K, Narimatsu S, Taguchi K, et al.
    • Journal Title

      Journal of Health Science

      Volume: 57 Pages: 107-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1,2-naphthoquinone2011

    • Author(s)
      Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y
    • Journal Title

      Chem Res Toxicol

      Volume: 24 Issue: 4 Pages: 559-567

    • DOI

      10.1021/tx100427p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22406004, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Two-electron quinone reductase (AKR1C isozyme)augments the oxidative DNA damage induced by quinones in diesel exhaust particles by accelerating redox cycling2011

    • Author(s)
      Yamano S, Shibata M, Kita H, Matsusue K, Narimatsu S, Taguchi K, Kumagai Y
    • Journal Title

      J Health Sci

      Volume: 57 Pages: 107-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2011

    • Author(s)
      田口恵子
    • Journal Title

      東北醫學雑誌

      Volume: 123 Pages: 51-45

    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011

    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 12011

    • Author(s)
      Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL
    • Journal Title

      J Biochem Mol Toxicol

      Volume: 25 Issue: 5 Pages: 320-329

    • DOI

      10.1002/jbt.20392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2011

    • Author(s)
      田口恵子
    • Journal Title

      東北醫學雑誌

      Volume: 123 Pages: 51-54

    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1,2-naphthoquinone2011

    • Author(s)
      Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, et al.
    • Journal Title

      Chemical Research in Toxicology

      Volume: (未定 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1, 2-naphthoquinone2011

    • Author(s)
      Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y
    • Journal Title

      Chem Res Toxicol

      Volume: 24 Pages: 559-567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011

    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011

    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Issue: 1 Pages: 13-18

    • DOI

      10.1016/j.bbrc.2010.12.092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163
  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011

    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 2 Pages: 123-140

    • DOI

      10.1111/j.1365-2443.2010.01473.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 12011

    • Author(s)
      Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL
    • Journal Title

      J Biochem Mol Toxicol

      Volume: 25 Pages: 320-329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011

    • Author(s)
      Inoue D, Kubo H, Taguchi K, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The transcriptome of Nrf2^<-/-> Mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
    • Journal Title

      Tox Sci

      Volume: 115 Pages: 238-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway : a potential role for protein aggregation in autophagic substrate selection2010

    • Author(s)
      Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, Yamamoto M, Tanaka K, Mizushima N, Komatsu M, Kopito RR
    • Journal Title

      J Cell Biol

      Volume: 191 Pages: 537-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Deletion of Nuclear Factor-E2-Related Factor-2 Leads to Rapid Onset and Progression of Nutritional Steatohepatitis in Mice2010

    • Author(s)
      Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, and Yamamoto M
    • Journal Title

      Nature Cell Biol

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway : a potential role for protein aggregation in autophagic substrate selection2010

    • Author(s)
      Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, et al.
    • Journal Title

      Journal of Cell Biology

      Volume: 191 Pages: 537-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, et al.
    • Journal Title

      Nature Cell Biology

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The transcriptome of Nrf2-/-mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
    • Journal Title

      Toxicol Sci

      Volume: 115 Pages: 238-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap12010

    • Author(s)
      Taguchi K, et al.
    • Journal Title

      Molecular and Cellular Biology

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010

    • Author(s)
      Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 1833-1843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010

    • Author(s)
      Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 298 Pages: 283-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y. S., Ueno, I., Sakamoto, A., Tong, K. I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M.
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010

    • Author(s)
      Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, et al.
    • Journal Title

      Toxicological Sciences

      Volume: 115 Pages: 238-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010

    • Author(s)
      Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 1833-1843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap12010

    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M
    • Journal Title

      Nat Cell Biol

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010

    • Author(s)
      Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, et al.
    • Journal Title

      American Journal of Physiology Gastrointestinal and Liver Physiology

      Volume: 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y.S., Ueno, I., Sakamoto, A., Tong, K.I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M
    • Journal Title

      Nat Cell Biol. 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic versus chemoprotective activation of Nrf2 signaling : overlapping yet distinct gene expression profiles between Keap 1 knockout and trite rpenoid treated mice2009

    • Author(s)
      Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW.
    • Journal Title

      Carcinogenesis 30

      Pages: 1024-1031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009

    • Author(s)
      Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun 389

      Pages: 431-436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 1-Cyano-2, 3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic{alpha}, {beta}-unsaturated aldehyde acrolein2009

    • Author(s)
      Kelleher MO, McMahon M, Eggleston IM, Dixon MJ, Taguchi K, Yamamoto M, Hayes JD.
    • Journal Title

      Carcinogenesis 30

      Pages: 1754-1762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Redox cycling of 9, 10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells2008

    • Author(s)
      Taguchi K, Shimada M, 他
    • Journal Title

      Free Radical Biology and Medicine 44

      Pages: 1645-1655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 酸化ストレス防御のための生体内センサー:Keap1-Nrf2制御システム2007

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      化学と生物 45

      Pages: 857-862

    • NAID

      10019973647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.2007

    • Author(s)
      Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, and Kumagai Y.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 645-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] NRF2活性化がん:古き実験動物モデルから診断と治療に向けて2023

    • Author(s)
      田口恵子
    • Organizer
      第50回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06906
  • [Presentation] NRF2-activated Cancers and Toxicology2023

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      10th International Congress of Asian Society of Toxicology (ASIATOX-X)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06906
  • [Presentation] NRF2 activation status determines cell competition in the esophagus2023

    • Author(s)
      Keiko Taguchi, Wataru Hirose, Masayuki Yamamoto
    • Organizer
      Society of Toxicology (SOT) 62nd annual meeting and ToxExpo
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06906
  • [Presentation] Protective effects of Nrf2 against radiation-induced oral mucositis2023

    • Author(s)
      Keiko Taguchi, Shun Wakamori, Masayuki Yamamoto
    • Organizer
      The 3rd STINT-JSPS symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06906
  • [Presentation] 食道上皮におけるNrf2活性化細胞の排除メカニズム2021

    • Author(s)
      廣瀬亘、田口恵子、堀内真、亀井 尚、山本雅之
    • Organizer
      日本生化学会東北支部第87 回例会・シンポジウム
    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Presentation] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2020

    • Author(s)
      田口恵子
    • Organizer
      第402回東北医学会例会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Presentation] ラットモデルを用いたNrf2活性化が引き起こす病態の解明2020

    • Author(s)
      田口恵子、山本雅之
    • Organizer
      第19回分子予防環境医学研究会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Presentation] Aflatoxin B1 induces fibrosis and cirrhosis in Nrf2 knockout rats2019

    • Author(s)
      Keiko Taguchi, Nanae Osanai, Eriko Naganuma, Thomas W. Kensler, Masayuki Yamamoto
    • Organizer
      58th Annual Meeting of Society of Toxicology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Keap1-Nrf2 system: Findings using animal models2019

    • Author(s)
      Keiko Taguchi
    • Organizer
      National Institute on Aging/National Institute of Health (NIA/NIH) seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Unveiling new roles of Keap1-Nrf2 System by using rat models2019

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      The Environmental Response V
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07395
  • [Presentation] Keap1欠失ラットは転写因子Nrf2の活性化により重篤な肝障害を引き起こす2019

    • Author(s)
      田口恵子、小山内七重、佐藤由莉、宮坂佳樹、真下知士、山本雅之
    • Organizer
      平成30年度先端モデル動物支援プラットフォーム成果発表会
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Nrf2 activation-acquired Liver cancer2017

    • Author(s)
      Keiko Taguchi
    • Organizer
      Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
    • Place of Presentation
      ピッツバーグ・アメリカ
    • Year and Date
      2017-03-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] 毒性学における転写因子Nrf2の貢献2017

    • Author(s)
      田口恵子、山本雅之
    • Organizer
      第44回日本毒性学会学術年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Simultaneous activation of K-ras and Nrf2 induce pancreatic atrophy2017

    • Author(s)
      Hamada Shin, Masamune Atsushi, Taguchi Keiko, Yamamoto Masayuki and Shimosegawa Tooru
    • Organizer
      Digestive Disease Week
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] 毒性学におけるNrf2欠失ラットの貢献2017

    • Author(s)
      田口恵子、山本雅之
    • Organizer
      第10回ラットリソースリサーチ研究会
    • Place of Presentation
      京都大学芝蘭会館稲盛ホール(京都)
    • Year and Date
      2017-02-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Nrf2 activation-acquired Liver cancer2017

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2017-03-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] The Nrf2 knockout rat as a toxicological tool2017

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
    • Organizer
      Society of Toxicology 56th Annual Meeting
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2017-03-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] 毒性学におけるNrf2欠失ラットの貢献2017

    • Author(s)
      田口恵子、山本雅之
    • Organizer
      第10回ラットリソースリサーチ研究会
    • Place of Presentation
      京都大学芝蘭会館稲盛ホール(京都)
    • Year and Date
      2017-02-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 activation-acquired Liver cancer2017

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2017-03-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] 毒性学におけるNrf2欠失ラットの貢献2017

    • Author(s)
      田口恵子、山本雅之
    • Organizer
      第10回ラットリソースリサーチ研究会
    • Place of Presentation
      京都大学芝蘭会館稲盛ホール(京都)
    • Year and Date
      2017-02-03
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Pten欠失肝臓がんにおけるNrf2活性獲得の意義2017

    • Author(s)
      田口恵子、一戸理沙、山本雅之
    • Organizer
      第5回がんと代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] オートファジーとKeap1-Nrf2システム2017

    • Author(s)
      田口恵子
    • Organizer
      第44回日本毒性学会学術年会
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Nrf2 knockout suppresses pancreatic carcinogenesis in a mouse model2017

    • Author(s)
      Shin Hamada, Atsushi Masamune, Keiko Taguchi, Masayuki Yamamoto, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2017-05-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04804
  • [Presentation] Nrf2 activation acquired in a transition from steatosis to liver cancer2017

    • Author(s)
      Keiko Taguchi, Risa Ichinohe, Masayuki Yamamoto
    • Organizer
      2017 International Congress Obesity and Metabolic Syndrome (ICOMES2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Nrf2 activation acquired in a transition from steatosis to liver cancer2017

    • Author(s)
      Keiko Taguchi, Risa Ichinohe, Masayuki Yamamoto
    • Organizer
      2017 International Congress Obesity and Metabolic Syndrome (ICOMES2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] The Nrf2 knockout rat as a toxicological tool2017

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
    • Organizer
      56th Annual Meeting of Society of Toxicology
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2017-03-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] オートファジーとKeap1-Nrf2システム2017

    • Author(s)
      田口恵子
    • Organizer
      第44回日本毒性学会学術年会
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016

    • Author(s)
      田口恵子、増井紗帆、山本雅之
    • Organizer
      第43回日本毒性学会学術年会
    • Place of Presentation
      ウィンクあいち(名古屋)
    • Year and Date
      2016-06-29
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016

    • Author(s)
      田口恵子、増井紗帆、山本雅之
    • Organizer
      第43回日本毒性学会学術年会
    • Place of Presentation
      ウィンクあいち(名古屋)
    • Year and Date
      2016-06-29
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016

    • Author(s)
      田口恵子、小松雅明、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016

    • Author(s)
      田口恵子、小松雅明、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略2016

    • Author(s)
      田口恵子、鈴木隆史、山本雅之
    • Organizer
      第10回オートファジー研究会・第4回新学術「オートファジー」班会議
    • Place of Presentation
      NASPA ニューオータニ(新潟県越後湯沢)
    • Year and Date
      2016-11-13
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016

    • Author(s)
      Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
    • Place of Presentation
      Maui, USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016

    • Author(s)
      田口恵子、増井紗帆、山本雅之
    • Organizer
      第43回日本毒性学会学術年会
    • Place of Presentation
      ウィンクあいち(愛知県名古屋)
    • Year and Date
      2016-06-29
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016

    • Author(s)
      田口恵子、小松雅明、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略2016

    • Author(s)
      田口恵子、鈴木隆史、山本雅之
    • Organizer
      第10回オートファジー研究会
    • Place of Presentation
      NASPA ニューオータニ(越後湯沢)
    • Year and Date
      2016-11-13
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016

    • Author(s)
      Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
    • Organizer
      41st NAITO Conference
    • Place of Presentation
      CHATERAISE Gateaux Kingdom SAPPORO(札幌)
    • Year and Date
      2016-07-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016

    • Author(s)
      Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
    • Organizer
      41st NAITO Conference
    • Place of Presentation
      CHATERAISE Gateaux Kingdom SAPPORO(北海道札幌)
    • Year and Date
      2016-07-05
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 activation in liver cancer model mice2016

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
    • Place of Presentation
      Cagliari, Italy
    • Year and Date
      2016-06-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Nrf2 activation in liver cancer model mice2016

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
    • Place of Presentation
      カリアリ・イタリア
    • Year and Date
      2016-06-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190
  • [Presentation] Keiko Taguchi, Masayuki Yamamoto2016

    • Author(s)
      Keiko Taguchi, Masayuki Yamamoto
    • Organizer
      Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
    • Place of Presentation
      Cagliari, Italy
    • Year and Date
      2016-06-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016

    • Author(s)
      Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
    • Organizer
      41st NAITO Conference
    • Place of Presentation
      CHATERAISE Gateaux Kingdom SAPPORO(札幌)
    • Year and Date
      2016-07-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0325
  • [Presentation] Nrf2はPten欠失による脂肪肝炎から肝臓がんの移行を促進する2015

    • Author(s)
      田口恵子、一戸理沙、山本雅之
    • Organizer
      第88回日本生化学会/第38回日本分子生物学会合同大会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] 2つのタンパク質分解系による統合的なNrf2の制御メカニズム2015

    • Author(s)
      田口恵子
    • Organizer
      第88回日本生化学会大会
    • Place of Presentation
      神戸国際会場(神戸)
    • Year and Date
      2015-12-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2欠失ラットはアフラトキシンB1による肝毒性に対して脆弱である2015

    • Author(s)
      田口恵子、高久美咲、Thomas W. Kensler、山本雅之
    • Organizer
      第42回日本毒性学会学術年会
    • Place of Presentation
      石川県立音楽堂,金沢市アートホール、ホテル日航金沢(金沢)
    • Year and Date
      2015-06-29
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] A new tool for toxicology: Nrf2 knockout rat2015

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Masayuki Yamamoto
    • Organizer
      The 7th International Congress of Asian Society of Toxicology (ASIATOX2015)
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2015-06-23
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 Knockout Rat Is Sensitive to Aflatoxin B1 Hepatotoxicity2015

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
    • Organizer
      University of Pittsburgh Cancer Institute (UPCI) Scientific Retreat
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2015-06-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] タンパク質分解によるNrf2活性制御メカニズム2015

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸学院大学(神戸)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 はPten 欠失による脂肪肝炎から肝がんへの移行を促進する2015

    • Author(s)
      田口恵子、一戸理沙、山本雅之
    • Organizer
      第3回がんと代謝研究会・金沢大学がん進展制御研究所共同利用・共同研究拠点シンポジウム
    • Place of Presentation
      石川県立音楽堂交流ホール(金沢)
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] 肝毒性物質に応答した肝保護にはたらくNrf2の役割2014

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      日本生化学会東北支部第80回例会・シンポジウム
    • Place of Presentation
      アキタパークホテル
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
    • Organizer
      The Environmental Response IV
    • Place of Presentation
      Katahira Sakura Hall (Sendai)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Nrf2の活性制御破綻がもたらす肝病態2014

    • Author(s)
      田口恵子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Gyeonggi Institute of Science & Technology Promotion
    • Place of Presentation
      Gyeonggi Institute of Science & Technology Promotion, Suwon, Korea
    • Year and Date
      2014-06-19
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 写因子Nrf2はPten欠損肝臓において胆管増生を促進する2014

    • Author(s)
      6. 田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      加齢医学研究所第141回集談会
    • Place of Presentation
      仙台
    • Year and Date
      2014-01-17
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      2014 International Symposium and Annual Meeting of The Korean Society for Applied Biological Chemistry
    • Place of Presentation
      Haeundae Grand Hotel (Busan, Korea)
    • Year and Date
      2014-06-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] 肝毒性物質に応答した肝保護にはたらくNrf2の役割2014

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      日本生化学会東北支部第80回例会・シンポジウム
    • Place of Presentation
      アキタパークホテル(秋田)
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
    • Organizer
      The Environmental Response IV
    • Place of Presentation
      Katahira Sakura Hall (Sendai)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014

    • Author(s)
      1. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The Environmental Response IV
    • Place of Presentation
      sendai
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2の活性制御破綻がもたらす肝病態2014

    • Author(s)
      田口恵子
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] PtenとKeap1 - Nrf2システムの破綻が引き起こす肝病態の解析2014

    • Author(s)
      2. 田口恵子、本橋ほづみ、鈴木聡、山本雅之
    • Organizer
      平成25年度個体レベルでのがん研究支援活動ワークショップ
    • Place of Presentation
      大津
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する2014

    • Author(s)
      5. 田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究修飾シグナル病領域推進会議 (15)
    • Place of Presentation
      白金台
    • Year and Date
      2014-01-25
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] PtenとKeap1-Nrf2システムの破綻が引き起こす肝病態の解析2014

    • Author(s)
      田口恵子、本橋ほづみ、鈴木聡、山本雅之
    • Organizer
      平成25年度個体レベルでのがん研究支援活動ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      2014 International Symposium and Annual Meeting of the KSABC (The Korean Society for Applied Biological Chemistry
    • Place of Presentation
      Haeundae Grand Hotel, Busan, Korea
    • Year and Date
      2014-06-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Gyeonggi Institute of Science & Technology Promotion
    • Place of Presentation
      Gyeonggi Institute of Science & Technology Promotion (Suwon, Korea)
    • Year and Date
      2014-06-19
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] PtenとKeap1-Nrf2システムの破綻が引き起こす肝病態の解析2014

    • Author(s)
      田口恵子、本橋ほづみ、鈴木聡、山本雅之
    • Organizer
      平成25年度個体レベルでのがん研究支援活動ワークショップ
    • Place of Presentation
      琵琶湖ホテル(大津)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013

    • Author(s)
      田口恵子,本橋ほづみ,伊藤暢,田中稔,宮島篤,山本雅之
    • Organizer
      フォーラム2013:衛生薬学・環境トキシコロジー
    • Place of Presentation
      九州大学(博多)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2 enhances a hepatotoxin-induced hepatic cell expansion2013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
    • Organizer
      The XIII International Congress of Toxicology (ICT2013)
    • Place of Presentation
      Coex, Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 転写因子Nrf2の制御破綻が引き起こす肝病態2013

    • Author(s)
      12. 田口恵子
    • Organizer
      平成25年度がん研究分野の特性等を踏まえた支援活動公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2013-08-22
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013

    • Author(s)
      田口恵子,本橋ほづみ,伊藤暢,田中稔,宮島篤,山本雅之
    • Organizer
      フォーラム2013:衛生薬学・環境トキシコロジー
    • Place of Presentation
      九州大学(博多)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013

    • Author(s)
      13. 田口恵子、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究修飾シグナル病領域推進会議
    • Place of Presentation
      白金台
    • Year and Date
      2013-07-05
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] オートファジーによるKeaplタンパク質分解とレドックス恒常性維持2013

    • Author(s)
      3. 田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      GCOEシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2013-02-01
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013

    • Author(s)
      田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Two distinct mechanisms for degradation of a transcription factor Nrf22013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The 35th NAITO Conference
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
    • Place of Presentation
      東京大学医科学研究所/東京
    • Year and Date
      2013-02-01
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Nrf2 enhances a hepatotoxin - induced hepatic cell expansion2013

    • Author(s)
      15. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The XIII International Congress of Toxicology(ICT2013)
    • Place of Presentation
      Seoil, Korea
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013

    • Author(s)
      田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      新学術研究「修飾シグナル病」若手ワークショップ
    • Place of Presentation
      伊香保温泉
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝疾患における転写因子Nrf2の機能変化2013

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver, 1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling2013

    • Author(s)
      4. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The Auditorium, The Institute of Medical Science
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 酸化ストレス応答機構Keap1 - Nrf2システムと肝病態2013

    • Author(s)
      10. 田口恵子
    • Organizer
      第12回生物化学若手研究者セミナー酸化ストレスに応答機構研究の展開
    • Place of Presentation
      仙台
    • Year and Date
      2013-09-07
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Two distinct mechanisms for degradation of a transcription factor Nrf22013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The 35th NAITO Conference
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013

    • Author(s)
      田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝疾患における転写因子Nrf2の機能変化2013

    • Author(s)
      14. 田口恵子
    • Organizer
      新学術領域研究修飾シグナル病領域推進会議
    • Place of Presentation
      白金台
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝疾患における転写因子Nrf2の機能変化2013

    • Author(s)
      田口恵子
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013

    • Author(s)
      7. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      新学術研究修飾シグナル病若手ワークショップ
    • Place of Presentation
      伊香保
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] オートファジーによるKeap1タンパク質分解とレドックス恒常性維持2013

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      GCOEシンポジウム ~Network Medicineによる医学・生命科学の新たな潮流~
    • Place of Presentation
      艮陵会館/仙台
    • Year and Date
      2013-02-01
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013

    • Author(s)
      8. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      フォーラム2013 : 衛生薬学・環境トキシコロジー
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝疾患におけるNrf2の機能解析2013

    • Author(s)
      11. 田口恵子
    • Organizer
      第6回レドックス・ライフイノベーション第170委員会
    • Place of Presentation
      弘前
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013

    • Author(s)
      田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      新学術研究「修飾シグナル病」若手ワークショップ
    • Place of Presentation
      伊香保温泉
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2 enhances a hepatotoxin-induced hepatic cell expansion2013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
    • Organizer
      The XIII International Congress of Toxicology (ICT2013)
    • Place of Presentation
      Coex, Seoul, Korea
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] eciprocal activation between Nrf2 and a proliferative signaling in liver2013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
    • Place of Presentation
      東京大学医科学研究所/東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013

    • Author(s)
      9. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      第86回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2 system for maintenance of redox homeostasis2012

    • Author(s)
      Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The 6th International Congress of Asian Society of Toxicology (ASIATOX-VI)
    • Place of Presentation
      仙台国際会議場/仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] PI3K経路により変化する転写因子Nrf2の機能2012

    • Author(s)
      19. 田口恵子
    • Organizer
      がん・エピゲノム研究会
    • Place of Presentation
      仙台
    • Year and Date
      2012-10-24
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      17. 田口恵子、本橋ほづみ、山本雅之
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      18. 田口恵子、本橋ほづみ、山本雅之
    • Organizer
      フォーラム2012:衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1 Degradation by Autophagy for the Maintenance of Redox Homeostasis2012

    • Author(s)
      Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      UK-Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      つくばサイエンスインフォメーションセンター/つくば
    • Year and Date
      2012-04-06
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      フォーラム2012:衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋観光ホテル/名古屋
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Crosstalk between Keap1-Nrf2 system and Pten-PI3K-Akt signaling regulates cellular proliferation and differentiation2012

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi , Masayuki Yamamoto
    • Organizer
      The 33rd NAITO Conference “Oxygen Biology: Hypoxia, Oxidative Stress and Diseases”
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ/札幌
    • Year and Date
      2012-06-26
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Keap1 Degradation by Autophagy for the Maintenance of Redox Homeostasis2012

    • Author(s)
      Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      UK-Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      つくばサイエンスインフォメーションセンター/つくば
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保温泉
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] Crosstalk between Keap1-Nrf2 system and Pten-PI3K-Akt signaling regulates cellular proliferation and differentiation2012

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi , Masayuki Yamamoto
    • Organizer
      The 33rd NAITO Conference “Oxygen Biology: Hypoxia, Oxidative Stress and Diseases”
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ/札幌
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡国際会議場/福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] PI3K経路により変化する転写因子Nrf2の機能2012

    • Author(s)
      田口恵子
    • Organizer
      がん・エピゲノム研究会
    • Place of Presentation
      艮陵会館/仙台
    • Year and Date
      2012-10-24
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Keap1-Nrf2システムとPI3K-Akt経路のクロストークと肝病態2012

    • Author(s)
      田口恵子,本橋ほづみ,山本雅之
    • Organizer
      2012年度新学術領域「転写代謝システム」班会議
    • Place of Presentation
      つくばグランドホテル/つくば
    • Year and Date
      2012-07-02
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保(宮城)
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Keap1 - Nrf2システムとPten - PI3K - Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      25. 田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2012

    • Author(s)
      16. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Kumamoto University Core Research Project B "Center for Frontier Research on Life Style an Stress Signal" and Grants-in-Aid for Scientific Research on Innovative Areas(Research in a Proposed Research Area), MEXT, Japan "Signaling Functions of Reactive Oxygen Species" Joint Symposium
    • Place of Presentation
      Kumamoto
    • Year and Date
      2012-12-18
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2システムとPI3K-Akt経路のクロストークと肝病態2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      2012年度新学術領域「転写代謝システム」班会議
    • Place of Presentation
      つくばグランドホテル/つくば
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in metabolic reprogramming2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Aburatani H, Yamamoto M, Motohashi H
    • Organizer
      Keystone Symposium on Cancer and Metabolism
    • Place of Presentation
      アルバータ、カナダ
    • Year and Date
      2012-02-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] レドックス恒常性維持に重要なオートファジーによるKeaplタンパク質の分解2012

    • Author(s)
      20. 田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      2012年度新学術領域研究修飾シグナル病若手ワークショップ
    • Place of Presentation
      湯河原
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keapl - Nrf3 system for maintenance of redox homeostasis2012

    • Author(s)
      21. Keiko Taguchi, Nanako Fu j ikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Symposium Molecular toxicology: update, AS3 - 4, The 7th International Congress of Asian Society of Toxicology(ASIATOX-VI)
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      フォーラム2012:衛生薬学・環境トキシコロジー
    • Place of Presentation
      名古屋観光ホテル/名古屋
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] レドックス恒常性維持に重要なオートファジーによるKeap1タンパク質の分解2012

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      2012年度新学術領域研究「修飾シグナル病」若手ワークショップ
    • Place of Presentation
      ホテルあかね/湯河原
    • Year and Date
      2012-10-03
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2012

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Kumamoto University Core Research Project B and Grants-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area), MEXT, Japan Joint Symposium
    • Place of Presentation
      アークホテル熊本城前/熊本
    • Year and Date
      2012-12-18
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      第85回日本生化学会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2 system for maintenance of redox homeostasis2012

    • Author(s)
      Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The 6th International Congress of Asian Society of Toxicology (ASIATOX-VI)
    • Place of Presentation
      仙台国際会議場/仙台
    • Year and Date
      2012-07-17
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Keap1 - Nrf2システムとPI3K - Akt経路のクロストークと肝病態2012

    • Author(s)
      24. 田口恵子、本橋ほづみ、山本雅之
    • Organizer
      2012年度新学術領域転写代謝システム班会議
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保
    • Year and Date
      2012-02-04
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keapl Degradation by Autophagy for the Maintenance of Redox Homeostasis2012

    • Author(s)
      23. Keiko Taguchi, Nanako Fu j ikawa, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      UK - Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
    • Place of Presentation
      Tsukuba
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] レドックス恒常性維持に重要なオートファジーによるKeap1タンパク質の分解2012

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      2012年度新学術領域研究「修飾シグナル病」若手ワークショップ
    • Place of Presentation
      ホテルあかね/湯河原
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Crosstalk between Keapl - Nrf2 system and Pten - PI3K-Akt signaling regulates cellular proliferation and differentiation2012

    • Author(s)
      22. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      The 33rd NAITO Conference Oxygen Biology : Hypoxia, Oxidative Stress and Diseases"
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保(宮城)
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] Co-activation of Nrf2 and Akt causes bile ductal metaplasia2011

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Tohoku University Global COE for conquest of Signal Transduction Diseases with "Network Medicine" Network Medicine Winter Camp of GCOE
    • Place of Presentation
      宮城県秋保
    • Year and Date
      2011-02-05
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] 転写因子Nrf2欠損はウレタン誘導性肺発癌を減少させ、Nrf2欠損癌組織は免疫不全マウスで著しい生着不全と増殖能低下をきたす2011

    • Author(s)
      佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011

    • Author(s)
      田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] マウス遺伝学解析に基盤とするKeap1-Nrf2システムの解明2011

    • Author(s)
      山本雅之、鈴木隆史、田口恵子、本橋ほづみ
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Nanako Fujikawa, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Hotel Rodos Palace, Rhodes Island in Greece
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] レドックス恒常性維持に重要なKeap1分解機構の解明2011

    • Author(s)
      藤川奈々子、田口恵子、本橋ほづみ、山本雅之
    • Organizer
      平成23年度がん若手ワークショップ
    • Place of Presentation
      蓼科
    • Year and Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      ギリシャ・ロードス島
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] Keap1-Nrf2システムとAktシグナルの相互作用と肝疾患2011

    • Author(s)
      田口恵子, 本橋ほづみ, 山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京
    • Year and Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Yoichiro Mitsuishi, Keiko Taguchi, Masayuki Yamamoto, Hozumi Motohashi
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      ギリシャ・ロードス島
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] Transcription factor Nrf2 drives the pentose phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Yoichiro Mitsuishi, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Discovery on Target ; Cancer Cell Metabolism as Drug Target
    • Place of Presentation
      Boston, USA
    • Year and Date
      2011-11-02
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011

    • Author(s)
      田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢市
    • Data Source
      KAKENHI-PUBLICLY-23117503
  • [Presentation] 転写因子Nrf2はペントースリン酸経路とグルタミン代謝を制御して細胞増殖に貢献する2011

    • Author(s)
      光石陽一郎、田口恵子、油谷浩幸、貫和敏博、本橋ほづみ、山本雅之
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011

    • Author(s)
      田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 上皮細胞における転写因子Nrf2の活性化2010

    • Author(s)
      田口恵子、鈴木隆史、本橋ほづみ、山本雅之
    • Organizer
      フォーラム2010:衛生薬学・環境トキシコロジー
    • Place of Presentation
      星薬科大学
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] Co-activation of Nrf2 and Akt causes bile ductal metaplasia2010

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Tohoku University Global COE for conquest of Signal Transduction Diseases with"Network Medicine", Network Medicine Winter Camp of GCOE
    • Place of Presentation
      Akiu, Miyagi
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] 上皮細胞における転写因子Nrf2の活性化2010

    • Author(s)
      田口恵子、鈴木隆史、本橋ほづみ、山本雅之
    • Organizer
      日本生化学会東北支部会第76回例会・シンポジウム
    • Place of Presentation
      福島
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf2は宿主肺における癌転移抑制因子である2010

    • Author(s)
      佐藤大希、田口恵子、森口尚、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第50回日本呼吸器学会学術総会
    • Place of Presentation
      湯沢
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 宿主におけるNrf2欠損はMDSCs細胞に著明な酸化ストレスの蓄積を誘導し、肺癌転移に対して有利な微小環境を創造する2010

    • Author(s)
      佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 上皮細胞における転写因子Nrf2の活性化2010

    • Author(s)
      田口恵子、鈴木隆史、本橋ほづみ、山本雅之
    • Organizer
      第76回日本生化学会東北支部会例会
    • Place of Presentation
      コラッセ福島
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-22790127
  • [Presentation] Nrf2 acts as a novel metastasis suppressor in the lung2009

    • Author(s)
      Satoh H, Taguchi K, Moriguchi T, Suzuki T, Ebina M, Nukiwa T, Yamamoto M.
    • Organizer
      68回日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] New function of host NRF2 in lung cancer2009

    • Author(s)
      佐藤大希, 田口恵子, 森口尚, 鈴木隆史, 海老名雅仁, 貫和敏博, 山本雅之
    • Organizer
      Interdisciplinary Force 学生成果発表会
    • Place of Presentation
      仙台
    • Year and Date
      2009-08-04
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Cell tyte-specific Nrf2 activation : different feature in hepatocytes and epithelial cells2009

    • Author(s)
      Taguchi K, Yamamoto M.
    • Organizer
      CDBIM symposium
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] PI3K経路により変化する転写因子Nrf2の機能

    • Author(s)
      田口恵子
    • Organizer
      がん・エピゲノム研究会
    • Place of Presentation
      艮陵会館/仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Kumamoto University Core Research Project B and Grants-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area), MEXT, Japan Joint Symposium
    • Place of Presentation
      アークホテル熊本城前/熊本
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Establishment and characterization of Nrf2 knockout rats

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
    • Organizer
      2nd International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
    • Place of Presentation
      東京大学医科学研究所(白金台)(東京)
    • Year and Date
      2015-01-23 – 2015-01-24
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する

    • Author(s)
      田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Multi-step regulation of Nrf2 activity in the liver

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Japan/Korea Joint Symposium on Pharmaceutical Health Science and Environmental Toxicology
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2014-09-19 – 2014-09-20
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 酸化ストレス応答機構Keap1-Nrf2システムと肝病態

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      第12回生物化学若手研究者セミナー
    • Place of Presentation
      東北薬科大学(仙台)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する

    • Author(s)
      田口恵子、白崎圭一、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 転写因子Nrf2の活性制御メカニズムと病態

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      若手放射線生物学研究会勉強会
    • Place of Presentation
      京都大学原子炉実験所
    • Year and Date
      2014-08-08 – 2014-08-10
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 転写因子Nrf2はPten欠損肝臓において胆管増生を促進する

    • Author(s)
      田口恵子、山本雅之、本橋ほづみ
    • Organizer
      加齢医学研究所第141回集談会
    • Place of Presentation
      東北大(仙台)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] 転写因子Nrf2の活性制御メカニズムと病態

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      若手放射線生物学研究会勉強会
    • Place of Presentation
      京都大学原子炉実験所(大阪)
    • Year and Date
      2014-08-08 – 2014-08-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] 酸化ストレス応答機構Keap1-Nrf2システムと肝病態

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      第12回生物化学若手研究者セミナー
    • Place of Presentation
      東北薬科大学(仙台)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] オートファジーによるKeap1タンパク質分解とレドックス恒常性維持

    • Author(s)
      田口恵子、藤川奈々子、本橋ほづみ、山本雅之
    • Organizer
      GCOEシンポジウム ~Network Medicineによる医学・生命科学の新たな潮流~
    • Place of Presentation
      艮陵会館/仙台
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Establishment and characterization of Nrf2 knockout rats

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
    • Organizer
      Biochemical Society-The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Robinson College, Cambridge, UK
    • Year and Date
      2015-01-06 – 2015-01-08
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] Establishment and characterization of Nrf2 knockout rats

    • Author(s)
      Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
    • Organizer
      Biochemical Society-The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Robinson College, Cambridge, UK
    • Year and Date
      2015-01-06 – 2015-01-08
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Liver diseases caused by perturbation of Nrf2 regulation

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 転写因子Nrf2はPten欠損肝臓において胆管増生を促進する

    • Author(s)
      田口恵子、山本雅之、本橋ほづみ
    • Organizer
      加齢医学研究所第141回集談会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PUBLICLY-25117703
  • [Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京大学医科学研究所(白金台)
    • Data Source
      KAKENHI-PROJECT-24790307
  • [Presentation] Multi-step regulation of Nrf2 activity in the liver

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Japan/Korea Joint Symposium on Pharmaceutical Health Science and Environmental Toxicology
    • Place of Presentation
      つくば国際会議場(つくば)
    • Year and Date
      2014-09-19 – 2014-09-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460384
  • [Presentation] Liver diseases caused by perturbation of Nrf2 regulation

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26460384
  • []

  • []

  • 1.  YAMAMOTO Masayuki (50166823)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 42 results
  • 2.  SUZUKI Takafumi (70508308)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 3.  Masamune Atsushi (90312579)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 4.  濱田 晋 (20451560)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 5.  KATSUOKA Fumiki (30447255)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  MINEGISHI Naoko (40271895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  MOTOHASHI Hozumi (00282351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 8.  KUROKAWA Hirofumi (80359546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  SUZUKI Norio (20447254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 10.  MORIGUCHI Takashi (10447253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 11.  赤池 孝章 (20231798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  Kensler Thomas W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  Columbano Amedeo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Cuadrado Antonio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TANAKA Minoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  ITOH Tohru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  宮島 篤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  丸山 和一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  宮崎 陽一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  石田 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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