Taguchi Keiko 田口恵子

… Alternative Names

TAGUCHI Keiko 田口恵子

Less

Researcher Number	20466527
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 准教授
Affiliation (based on the past Project Information) *help	2023: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2019 – 2023: 東北大学, 医学系研究科, 准教授 2017 – 2019: 東北大学, 医学系研究科, 講師 2015 – 2016: 東北大学, 医学系研究科, 助教 2015: 東北大学, 医学(系)研究科(研究院), 助教 … More 2013 – 2014: 東北大学, 加齢医学研究所, 助教 2012: 東北大学, 医学(系)研究科(研究院), 助教 2010 – 2011: 東北大学, 大学院・医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Biological Sciences / Basic Section 49010:Pathological biochemistry-related / Environmental pharmacy Except Principal Investigator Basic Section 53010:Gastroenterology-related / Medium-sized Section 48:Biomedical structure and function and related fields / Broad Section H / Gastroenterology
Keywords	Principal Investigator Nrf2 / 肝臓 / 転写因子 / がん / Keap1 / オートファジー / 肝臓がん / 遺伝子改変ラット / 食道がん / 細胞競合 … More / 食道 / 腫瘍 / 化学発がん / 肝腫瘍 / 肝がん / 肝肥大 / 門脈枝結紮 / 増殖 / Aktシグナル / 肝疾患 / 翻訳後修飾 / Akt / タンパク質分解 / 蛋白質分解 … More Except Principal Investigator 酸化ストレス / Keap1 / Nrf2 / 活性硫黄 / 活性イオウ / 膵癌 / KEAP1-NRF2系 / 健康長寿 / 加齢関連疾患 / Keap1-Nrf2制御系 / ストレス応答 / 膵癌モデルマウス / KPCマウス / 遺伝子 / ストレス / 環境 / 発現制御 / エリスロポエチン / 低酸素 / 環境応答 Less

肝臓の組織構築におけるNrf2の新たな機能Principal Investigator
- Principal Investigator
  
  田口恵子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  The University of Tokyo
  Tohoku University
硫黄生物学から紐解く膵癌難治化機構の解明と治療応用
- Principal Investigator
  
  正宗淳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Development of esophagus cancer acquired Nrf2 activationPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Keiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku University
Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy
- Principal Investigator
  
  Yamamoto Masayuki
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section H
- Research Institution
  Tohoku University
生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用
- Principal Investigator
  
  山本雅之
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Tohoku University
Development of novel therapy for pancreatic cancer based on the regulation of oxidative stress responses
- Principal Investigator
  
  Masamune Atsushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tohoku University
Hepatic tumor and Nrf2 activation by impaired autophagy(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Taguchi Keiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略Principal Investigator
- Principal Investigator
  
  田口恵子
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Role of oxidative stress response in pancreatic diseases and therapeutic application
- Principal Investigator
  
  Masamune Atsushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tohoku University
Hepatic tumor and Nrf2 activation by impaired autophagyPrincipal Investigator
- Principal Investigator
  
  Taguchi Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
肝疾患における転写因子Nrf２の機能変化Principal Investigator
- Principal Investigator
  
  田口恵子
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Role of Nrf2 in compensatory liver proliferation after portal vein branch ligation in micePrincipal Investigator
- Principal Investigator
  
  TAGUHI Keiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University
Ｋｅａｐ１－Ｎｒｆ２システムとＡｋｔシグナルの相互作用と肝疾患Principal Investigator
- Principal Investigator
  
  田口恵子
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Pathogenesis by disrupting the cytoprotective systemPrincipal Investigator
- Principal Investigator
  
  TAGUCHI Keiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Tohoku University
Molecular Mechanisms of Adaptive Responses to Food and Oxygen
- Principal Investigator
  
  YAMAMOTO Masayuki
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Tohoku University

[Book] Protein modifications in pathogenic dysregulation of signaling2015
- Author(s)
  Taguchi K, Yamamoto M
- Publisher
  Springer
- Data Source
  KAKENHI-PUBLICLY-25117703
[Book] Protein modifications in pathogenic dysregulation of signaling, Chapter 17 Keap1-Nrf2 regulatory system and cancer2015
- Author(s)
  Taguchi K, Yamamoto M
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460384
[Book] Protein modifications in pathogenic dysregulation of signaling2015
- Author(s)
  Taguchi K, Yamamoto M
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26460384
[Book] 毒性の科学―分子・細胞から人間集団まで2014
- Author(s)
  1. 田口恵子
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PUBLICLY-25117703
[Book] 「毒性の科学―分子・細胞から人間集団まで」第２章３節Keap1-Nrf2システムと毒物の解毒・排泄2014
- Author(s)
  田口恵子
- Total Pages
  200
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-24790307
[Book] 毒性の科学一分子、細胞から人間集団まで、第2章3節Keap1 - Nrf2システムと毒物の解毒・排泄2014
- Author(s)
  田口恵子
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-24790307
[Book] 「毒性の科学―分子・細胞から人間集団まで」第２章３節Keap1-Nrf2システムと毒物の解毒・排泄2014
- Author(s)
  田口恵子
- Total Pages
  200
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PUBLICLY-25117703
[Book] 酸化ストレスの医学改訂第２版2014
- Author(s)
  田口恵子、山本雅之
- Total Pages
  444
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26460384
[Book] 酸化ストレスの医学改訂第２版2014
- Author(s)
  2. 田口恵子、山本雅之
- Total Pages
  444
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PUBLICLY-25117703
[Book] 第２章３節Keap1-Nrf2システムと毒物の解毒・排泄、「毒性の科学―分子・細胞から人間集団まで」2013
- Author(s)
  田口恵子
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PUBLICLY-23117503
[Book] 第２章３節Keap1-Nrf2システムと毒物の解毒・排泄、「毒性の科学―分子・細胞から人間集団まで」2013
- Author(s)
  田口恵子
- Publisher
  東京大学出版会
- Data Source
  KAKENHI-PROJECT-24790307
[Book] 活性酸素種や親電子性物質によるシグナル伝達実験医学2012増刊号「シグナル伝達研究の最前線 2012-2013」2012
- Author(s)
  田口恵子、山本雅之
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790127
[Book] 第３章６節「代謝リプログラミングにおける酸化ストレス応答機構の役割」、活性酸素・ガス状分子による恒常性制御と疾患、『実験医学』2012増刊号2012
- Author(s)
  田口恵子、本橋ほづみ
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790307
[Book] 第３章６節「代謝リプログラミングにおける酸化ストレス応答機構の役割」、活性酸素・ガス状分子による恒常性制御と疾患、『実験医学』2012増刊号2012
- Author(s)
  田口恵子、本橋ほづみ
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23117503
[Book] 第２章７節「活性酸素種や親電子性物質によるシグナル伝達」、シグナル伝達研究の最前線 2012-2013　『実験医学』2012増刊号2012
- Author(s)
  田口恵子、山本雅之
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790307
[Book] 実験医学2012増刊号「シグナル伝達研究の最前線2012-2013」7.活性酸素種や親電子性物質によるシグナル伝達2012
- Author(s)
  田口恵子、山本雅之
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22790127
[Book] 第２章７節「活性酸素種や親電子性物質によるシグナル伝達」、シグナル伝達研究の最前線 2012-2013　『実験医学』2012増刊号2012
- Author(s)
  田口恵子、山本雅之
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23117503
[Book] 実験医学2012増刊号「シグナル伝達研究の最前線2012-2013」7.活性酸素種や親電子性物質によるシグナル伝達2012
- Author(s)
  田口恵子、山本雅之
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-23117503
[Journal Article] Metabolic reprogramming in Nrf2-driven proliferation of normal rat hepatocytes2023
- Author(s)
  Kowalik Marta A., Taguchi Keiko, Serra Marina, Caddeo Andrea, Puliga Elisabetta, Bacci Marina, Koshiba Seizo, Inoue Jin, Hishinuma Eiji, Morandi Andrea, Giordano Silvia, Perra Andrea, Yamamoto Masayuki, Columbano Amedeo
- Journal Title
  
  Hepatology
  
  Volume: 79 Issue: 4 Pages: 829-843
- DOI
  10.1097/hep.0000000000000568
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06906
[Journal Article] A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells2023
- Author(s)
  Baird Liam、Taguchi Keiko、Zhang Anqi、Takahashi Yushi、Suzuki Takafumi、Kensler Thomas W.、Yamamoto Masayuki
- Journal Title
  
  Redox Biology
  
  Volume: 66 Pages: 102845-102845
- DOI
  10.1016/j.redox.2023.102845
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H05649
[Journal Article] Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice2023
- Author(s)
  Shimizu Ritsuko、Hirano Ikuo、Hasegawa Atsushi、Suzuki Mikiko、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Uruno Akira、Suzuki Norio、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 875-875
- DOI
  10.1038/s42003-023-05251-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
[Journal Article] Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals2023
- Author(s)
  Aoki YI, Taguchi K, Anzawa H, Kawashima J, Ishida N, Otuki A, Hasegawa A, Baird L, Suzuki T, Motoike IN, Ohneda K, Kumada K, Katsuoka F, Kinoshita K, Yamamoto M.
- Journal Title
  
  J Biochem
  
  Volume: Online ahead of print. Issue: 6 Pages: 611-627
- DOI
  10.1093/jb/mvae008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
[Journal Article] Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium2023
- Author(s)
  Hirose Wataru、Horiuchi Makoto、Li Donghan、Motoike Ikuko N.、Zhang Lin、Nishi Hafumi、Taniyama Yusuke、Kamei Takashi、Suzuki Mikiko、Kinoshita Kengo、Katsuoka Fumiki、Taguchi Keiko、Yamamoto Masayuki
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 15 Issue: 1 Pages: 153-178
- DOI
  10.1016/j.jcmgh.2022.09.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-21K16466, KAKENHI-PROJECT-19H05649
[Journal Article] The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation <i>In Vivo</i>2022
- Author(s)
  Kuga Ayumi、Tsuchida Kouhei、Panda Harit、Horiuchi Makoto、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Suzuki Mikiko、Yamamoto Masayuki
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 42 Issue: 7 Pages: 1-22
- DOI
  10.1128/mcb.00563-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-19H05649
[Journal Article] Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening2022
- Author(s)
  Wakamori Shun、Taguchi Keiko、Nakayama Yuki、Ohkoshi Akira、Sporn Michael B.、Ogawa Takenori、Katori Yukio、Yamamoto Masayuki
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 188 Pages: 206-220
- DOI
  10.1016/j.freeradbiomed.2022.06.239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05649
[Journal Article] The KEAP1-NRF2 system and esophageal cancer2022
- Author(s)
  Hirose W, Oshikiri H, Taguchi K, Yamamoto M
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 19 Pages: 4702-4702
- DOI
  10.3390/cancers14194702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
[Journal Article] AHR and NRF2 in Skin Homeostasis and Atopic Dermatitis2022
- Author(s)
  Edamitsu T, Taguchi K, Okuyama R, Yamamoto M
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 2 Pages: 227-227
- DOI
  10.3390/antiox11020227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
[Journal Article] Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition2021
- Author(s)
  Hamada S, Matsumoto R, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Issue: 4 Pages: 1870-1870
- DOI
  10.3390/ijms22041870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08300, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03631
[Journal Article] Nrf2 expression in pancreatic stellate cells promotes progression of cancer.2021
- Author(s)
  Tanaka Y, Hamada S, Matsumoto R, Taguchi K, Yamamoto M, Masamune A.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 321 Issue: 4 Pages: G378-G388
- DOI
  10.1152/ajpgi.00120.2021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03631
[Journal Article] Nuclear factor erythroid 2-related factor 2 depletion sensitizes pancreatic cancer cells to gemcitabine via aldehyde dehydrogenase 3a1 repression.2021
- Author(s)
  Matsumoto R, Hamada S, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 379 Issue: 1 Pages: 33-40
- DOI
  10.1124/jpet.121.000744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03631
[Journal Article] 環境応答・適応の分子機構2021
- Author(s)
  田口恵子、山本雅之
- Journal Title
  
  日本体質医学学会誌
  
  Volume: 83 Pages: 38-45
- Data Source
  KAKENHI-PROJECT-19K07395
[Journal Article] The KEAP1-NRF2 system as a molecular target of cancer treatment2021
- Author(s)
  Taguchi K, Yamamoto M
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 1 Pages: 46-46
- DOI
  10.3390/cancers13010046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-16H06276
[Journal Article] Keap1-Nrf2システムによる生体機能制御機構の解明2020
- Author(s)
  田口恵子
- Journal Title
  
  東北醫學雑誌
  
  Volume: 132 Pages: 36-38
- Data Source
  KAKENHI-PROJECT-19K07395
[Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma.2020
- Author(s)
  Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03631
[Journal Article] Nrf2 in liver toxicology2020
- Author(s)
  2.Taguchi K, Kensler TW
- Journal Title
  
  Arch Pharmacal Res
  
  Volume: 43 Issue: 3 Pages: 337-349
- DOI
  10.1007/s12272-019-01192-3
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07395
[Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma2020
- Author(s)
  1.Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 318 Issue: 3 Pages: G419-G427
- DOI
  10.1152/ajpgi.00296.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
[Journal Article] Cellular Nrf2 levels determine cell fate during chemical carcinogenesis in esophageal epithelium2020
- Author(s)
  Horiuchi M, Taguchi K, Hirose W, Tsuchida K, Suzuki M, Taniyama Y, Kamei T, Yamamoto M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 41 Issue: 2
- DOI
  10.1128/mcb.00536-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649
[Journal Article] NRF2 in liver toxicology2019
- Author(s)
  Keiko Taguchi, Thomas W. Kensler
- Journal Title
  
  Archives of Pharmacal Research
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Journal Article] Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma2018
- Author(s)
  Hamada Shin、Shimosegawa Tooru、Taguchi Keiko、Nabeshima Tatsuhide、Yamamoto Masayuki、Masamune Atsushi
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 314 Issue: 1 Pages: G65-G74
- DOI
  10.1152/ajpgi.00228.2017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
[Journal Article] Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis2018
- Author(s)
  Orru Claudia、Szydlowska Marta、Taguchi Keiko、Zavattari Patrizia、Perra Andrea、Yamamoto Masayuki、Columbano Amedeo
- Journal Title
  
  Journal of Hepatology
  
  Volume: 69 Issue: 3 Pages: 635-643
- DOI
  10.1016/j.jhep.2018.05.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15KK0325
[Journal Article] The KEAP1-NRF2 system in cancer.2017
- Author(s)
  Taguchi K, Yamamoto M.
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 7 Pages: 85-85
- DOI
  10.3389/fonc.2017.00085
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KK0325, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002
[Journal Article] Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis2017
- Author(s)
  Hamada Shin、Taguchi Keiko、Masamune Atsushi、Yamamoto Masayuki、Shimosegawa Tooru
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Issue: 6 Pages: 661-670
- DOI
  10.1093/carcin/bgx043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
[Journal Article] Partial contribution of the Keap1-Nrf2 system to cadmium-mediated metallothionein expression in vascular endothelial cells.2016
- Author(s)
  Shinkai Y, Kimura T, Itagaki A, Yamamoto C, Taguchi K, Yamamoto M, Kumagai Y, Kaji T.
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 295 Pages: 37-46
- DOI
  10.1016/j.taap.2016.01.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-15K14992, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-24390034, KAKENHI-PUBLICLY-16H01190, KAKENHI-PROJECT-15KK0325
[Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016
- Author(s)
  Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
- Journal Title
  
  Nature Commun
  
  Volume: 7 Issue: 1 Pages: 12030-12030
- DOI
  10.1038/ncomms12030
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
[Journal Article] The transcription factor Bach2 is phosphorylated at multiple sites in murine B cells but a single site prevents its nuclear localization.2016
- Author(s)
  Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Pages: 1826-1840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460384
[Journal Article] Generation of a new model rat: Nrf2 knockout rats are sensitive to aflatoxin B1 toxicity.2016
- Author(s)
  Taguchi K, Takaku M, Egner PA, Morita M, Kaneko T, Mashimo T, Kensler TW, Yamamoto M.
- Journal Title
  
  Toxicol Sci
  
  Volume: in press Issue: 1 Pages: 40-52
- DOI
  10.1093/toxsci/kfw065
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460384, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26291005, KAKENHI-PROJECT-15KK0325, KAKENHI-INTERNATIONAL-15K21759
[Journal Article] Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.2015
- Author(s)
  Kanamori M*, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H*, and Tominaga T.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 17 Issue: 4 Pages: 555-565
- DOI
  10.1093/neuonc/nou282
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670613, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26860180
[Journal Article] 肝疾患における転写因子Nrf2の機能変化2015
- Author(s)
  田口恵子
- Journal Title
  
  別冊BIO Clinica
  
  Volume: 4 Pages: 159-161
- Data Source
  KAKENHI-PROJECT-26460384
[Journal Article] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.2014
- Author(s)
  Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, and Yamamoto M.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 34 Issue: 5 Pages: 900-913
- DOI
  10.1128/mcb.01384-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22118006, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-24116508, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670187, KAKENHI-PROJECT-26460384
[Journal Article] The circadian clock regulates rhythmic activation of the NRF2/glutathione - mediated antioxidant defense pathway to modulate pulmonary fibrosis2014
- Author(s)
  Pekovic, Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GT, Fukada Y, and Meng AJ.
- Journal Title
  
  Genes Dev
  
  Volume: 28(6) Pages: 548-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] The circadian clock regulates the NRF2/ARE-mediated antioxidant defence pathway in the mouse lung.2014
- Author(s)
  Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GTJ, Fukada Y, and Meng Q-J.
- Journal Title
  
  Genes Dev
  
  Volume: 28 Issue: 6 Pages: 548-560
- DOI
  10.1101/gad.237081.113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112504, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25440041, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-24227001
[Journal Article] Nrf2 Enhances Cholangiocyte Expansion in Pten - Deficient Livers2014
- Author(s)
  Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 34(5) Pages: 900-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Keapl inhibition attenuates glomerulosclerosis2014
- Author(s)
  Miyazaki Y, Shimizu A, Pastan I, T Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 29(4) Pages: 783-791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Nrf2 Promotes Compensatory Liver Hypertrophy after Portal Vein Branch Ligation in Mice2014
- Author(s)
  Shirasaki K, Taguchi K, Unno M, Motohashi H, Yamamoto M
- Journal Title
  
  Hepatology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] 癌細胞のグルコース・グルタミン代謝異常と癌遺伝子異常はどのように関連づけられるか2014
- Author(s)
  光石陽一郎、田口恵子
- Journal Title
  
  分子消化器病
  
  Volume: 11
- Data Source
  KAKENHI-PUBLICLY-25117703
[Journal Article] Nrf2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice.2014
- Author(s)
  Shirasaki K, Taguchi K, Unno M, Motohashi H, and Yamamoto M
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 6 Pages: 2371-2382
- DOI
  10.1002/hep.27020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150
[Journal Article] Keap1 inhibition attenuates glomerulosclerosis.2014
- Author(s)
  Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 29 Issue: 4 Pages: 783-791
- DOI
  10.1093/ndt/gfu002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112502, KAKENHI-PUBLICLY-25117703, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26461241
[Journal Article] Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death2013
- Author(s)
  Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T.
- Journal Title
  
  J Neurochem
  
  Volume: 127 Issue: 5 Pages: 669-680
- DOI
  10.1111/jnc.12325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592613, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703
[Journal Article] The role of the Nrf2 - mediated defense system in corneal epithelial wound healing2013
- Author(s)
  Hayashi R, Himori N, Taguchi K, Ishikawa Y, Uesugi K, Ito M, Duncan T, Tsu j ikawa M, Nakazawa T, Yamamoto M, Nishida K
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 61C Pages: 333-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] The role of the Nrf2-mediated defense system in corneal epithelial wound healing2013
- Author(s)
  Hayashi R, Himori N, Taguchi K, Ishikawa Y, Uesugi K, Ito M, Duncan T, Tsujikawa M, Nakazawa T, Yamamoto M, Nishida K
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 61C Pages: 333-342
- DOI
  10.1016/j.freeradbiomed.2013.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670731
[Journal Article] Critical role of Nrf2 in oxidative stress - induced retinal ganglion cell death2013
- Author(s)
  Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T
- Journal Title
  
  J Neurochem
  
  Volume: 127(5) Pages: 669-680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Metabolic stress response implicated in diabetic retinopathy: The role of calpain, and the therapeutic impact of calpain inhibitor.2012
- Author(s)
  Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, Taguchi K, Ysuda M, Watanabe R, Takano J, Saido T, Minegishi N, Miyata T, Abe T, Yamamoto M.
- Journal Title
  
  Neurobiological Disease
  
  Volume: 48 Issue: 3 Pages: 556-557
- DOI
  10.1016/j.nbd.2012.07.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24700472, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
[Journal Article] 活性酸素・ガス状分子による恒常性制御と疾患、第3章6節代謝リプログラミングにおける酸化ストレス応答機構…の役割2012
- Author(s)
  田口恵子、本橋ほづみ
- Journal Title
  
  実験医学 (羊土社)
  
  Volume: 30(17) Pages: 2814-2821
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Metabolic stress response implicated in diabetic retinopathy : the role of calpain, and the therapeutic impact of calpain inhibitor2012
- Author(s)
  Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, Taguchi K, Yasuda M, Watanabe R, Takano J, Takaomi S, Minegishi N, Miyata T, Abe T, Yamamoto M
- Journal Title
  
  Neurobiol Dis
  
  Volume: 48(3) Pages: 556-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: (in press)
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J.Gastroenterol
  
  Volume: (印刷中) Issue: 8 Pages: 924-935
- DOI
  10.1007/s00535-012-0552-9
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-22500656, KAKENHI-PROJECT-22590802, KAKENHI-PROJECT-22790127, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
[Journal Article] Keap1 degradation by autophagy for the maintenance of redox homeostasis2012
- Author(s)
  Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 34 Pages: 13561-13566
- DOI
  10.1073/pnas.1121572109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
[Journal Article] Keapl degradation by autophagy for the maintenance of redox homeostasis2012
- Author(s)
  Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109(34) Pages: 13561-13566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
- Author(s)
  Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M, Motohashi H
- Journal Title
  
  Cancer Cell
  
  Volume: 22(l) Pages: 66-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] シグナル伝達研究の最前線2012-2013第2章7節活性酸素種や親電子性物質によるシグナル伝達2012
- Author(s)
  田口恵子、山本雅之
- Journal Title
  
  実験医学 (羊土社)
  
  Volume: 30(5) Pages: 759-765
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] 転写因子Nrf2はグルコースとグルタミンの代謝を変化させて代謝リプログラミングを促進する2012
- Author(s)
  光石陽一郎、田口恵子、本橋ほづみ
- Journal Title
  
  ライフサイエンス新着論文レビュー
- URL
  http://first.1ifesciencedb.jp/archives/5262
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.2012
- Author(s)
  Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
- Journal Title
  
  Cancer Cell
  
  Volume: 22 Issue: 1 Pages: 66-79
- DOI
  10.1016/j.ccr.2012.05.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
[Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012
- Author(s)
  Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M and Motohashi H
- Journal Title
  
  Cancer Cell
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress - induced liver injury in nutritional steatohepatitis2012
- Author(s)
  Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
- Journal Title
  
  J Gastroenterol
  
  Volume: 47(8) Pages: 924-935
- NAID
  10031051379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790307
[Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
- Author(s)
  Taguchi K, Motohashi H, Yamamoto M
- Journal Title
  
  Genes to Cells
  
  Volume: 16 Pages: 123-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Two-electron quinone reductase (AKR1C isozyme) augments the oxidative DNA damage induced by quinones in diesel exhaust particles by accelerating redox cycling2011
- Author(s)
  Yamano S, Shibata M, Kita H, Matsusue K, Narimatsu S, Taguchi K, et al.
- Journal Title
  
  Journal of Health Science
  
  Volume: 57 Pages: 107-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1,2-naphthoquinone2011
- Author(s)
  Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y
- Journal Title
  
  Chem Res Toxicol
  
  Volume: 24 Issue: 4 Pages: 559-567
- DOI
  10.1021/tx100427p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22406004, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
[Journal Article] Two-electron quinone reductase (AKR1C isozyme)augments the oxidative DNA damage induced by quinones in diesel exhaust particles by accelerating redox cycling2011
- Author(s)
  Yamano S, Shibata M, Kita H, Matsusue K, Narimatsu S, Taguchi K, Kumagai Y
- Journal Title
  
  J Health Sci
  
  Volume: 57 Pages: 107-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2011
- Author(s)
  田口恵子
- Journal Title
  
  東北醫學雑誌
  
  Volume: 123 Pages: 51-45
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
- Author(s)
  Taguchi K, Motohashi H, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 16 Pages: 123-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 12011
- Author(s)
  Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL
- Journal Title
  
  J Biochem Mol Toxicol
  
  Volume: 25 Issue: 5 Pages: 320-329
- DOI
  10.1002/jbt.20392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
[Journal Article] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2011
- Author(s)
  田口恵子
- Journal Title
  
  東北醫學雑誌
  
  Volume: 123 Pages: 51-54
- Data Source
  KAKENHI-PUBLICLY-23117503
[Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1,2-naphthoquinone2011
- Author(s)
  Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, et al.
- Journal Title
  
  Chemical Research in Toxicology
  
  Volume: (未定印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1, 2-naphthoquinone2011
- Author(s)
  Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y
- Journal Title
  
  Chem Res Toxicol
  
  Volume: 24 Pages: 559-567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
- Author(s)
  Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 405 Pages: 13-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
- Author(s)
  Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 405 Issue: 1 Pages: 13-18
- DOI
  10.1016/j.bbrc.2010.12.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163
[Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011
- Author(s)
  Taguchi K, Motohashi H, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 16 Issue: 2 Pages: 123-140
- DOI
  10.1111/j.1365-2443.2010.01473.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 12011
- Author(s)
  Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL
- Journal Title
  
  J Biochem Mol Toxicol
  
  Volume: 25 Pages: 320-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011
- Author(s)
  Inoue D, Kubo H, Taguchi K, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 405 Pages: 13-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The transcriptome of Nrf2^<-/-> Mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010
- Author(s)
  Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
- Journal Title
  
  Tox Sci
  
  Volume: 115 Pages: 238-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway : a potential role for protein aggregation in autophagic substrate selection2010
- Author(s)
  Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, Yamamoto M, Tanaka K, Mizushima N, Komatsu M, Kopito RR
- Journal Title
  
  J Cell Biol
  
  Volume: 191 Pages: 537-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Deletion of Nuclear Factor-E2-Related Factor-2 Leads to Rapid Onset and Progression of Nutritional Steatohepatitis in Mice2010
- Author(s)
  Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
- Author(s)
  Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, and Yamamoto M
- Journal Title
  
  Nature Cell Biol
  
  Volume: 12 Pages: 213-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway : a potential role for protein aggregation in autophagic substrate selection2010
- Author(s)
  Riley BE, Kaiser SE, Shaler TA, Ng AC, Hara T, Hipp MS, Lage K, Xavier RJ, Ryu KY, Taguchi K, et al.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 191 Pages: 537-552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
- Author(s)
  Komatsu M, Kurokawa H, Waguri S, Taguchi K, et al.
- Journal Title
  
  Nature Cell Biology
  
  Volume: 12 Pages: 213-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The transcriptome of Nrf2-/-mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010
- Author(s)
  Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
- Journal Title
  
  Toxicol Sci
  
  Volume: 115 Pages: 238-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap12010
- Author(s)
  Taguchi K, et al.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 30 Pages: 3016-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010
- Author(s)
  Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 298 Pages: 283-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
- Author(s)
  Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y. S., Ueno, I., Sakamoto, A., Tong, K. I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M.
- Journal Title
  
  Nature Cell Biol 12
  
  Pages: 213-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010
- Author(s)
  Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 30 Pages: 3016-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010
- Author(s)
  Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, et al.
- Journal Title
  
  Toxicological Sciences
  
  Volume: 115 Pages: 238-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010
- Author(s)
  Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
- Journal Title
  
  Carcinogenesis
  
  Volume: 31 Pages: 1833-1843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap12010
- Author(s)
  Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 30 Pages: 3016-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
- Author(s)
  Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M
- Journal Title
  
  Nat Cell Biol
  
  Volume: 12 Pages: 213-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010
- Author(s)
  Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, et al.
- Journal Title
  
  American Journal of Physiology Gastrointestinal and Liver Physiology
  
  Volume: 298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790127
[Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010
- Author(s)
  Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y.S., Ueno, I., Sakamoto, A., Tong, K.I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M
- Journal Title
  
  Nat Cell Biol. 12
  
  Pages: 213-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Genetic versus chemoprotective activation of Nrf2 signaling : overlapping yet distinct gene expression profiles between Keap 1 knockout and trite rpenoid treated mice2009
- Author(s)
  Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW.
- Journal Title
  
  Carcinogenesis 30
  
  Pages: 1024-1031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009
- Author(s)
  Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M.
- Journal Title
  
  Biochem Biophys Res Commun 389
  
  Pages: 431-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] 1-Cyano-2, 3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic{alpha}, {beta}-unsaturated aldehyde acrolein2009
- Author(s)
  Kelleher MO, McMahon M, Eggleston IM, Dixon MJ, Taguchi K, Yamamoto M, Hayes JD.
- Journal Title
  
  Carcinogenesis 30
  
  Pages: 1754-1762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Redox cycling of 9, 10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells2008
- Author(s)
  Taguchi K, Shimada M, 他
- Journal Title
  
  Free Radical Biology and Medicine 44
  
  Pages: 1645-1655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] 酸化ストレス防御のための生体内センサー:Keap1-Nrf2制御システム2007
- Author(s)
  田口恵子、山本雅之
- Journal Title
  
  化学と生物 45
  
  Pages: 857-862
- NAID
  10019973647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Journal Article] Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.2007
- Author(s)
  Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, and Kumagai Y.
- Journal Title
  
  Biochem Biophys Res Commun. 363
  
  Pages: 645-650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] NRF2活性化がん：古き実験動物モデルから診断と治療に向けて2023
- Author(s)
  田口恵子
- Organizer
  第50回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06906
[Presentation] NRF2-activated Cancers and Toxicology2023
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  10th International Congress of Asian Society of Toxicology (ASIATOX-X)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06906
[Presentation] NRF2 activation status determines cell competition in the esophagus2023
- Author(s)
  Keiko Taguchi, Wataru Hirose, Masayuki Yamamoto
- Organizer
  Society of Toxicology (SOT) 62nd annual meeting and ToxExpo
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06906
[Presentation] Protective effects of Nrf2 against radiation-induced oral mucositis2023
- Author(s)
  Keiko Taguchi, Shun Wakamori, Masayuki Yamamoto
- Organizer
  The 3rd STINT-JSPS symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06906
[Presentation] 食道上皮におけるNrf2活性化細胞の排除メカニズム2021
- Author(s)
  廣瀬亘、田口恵子、堀内真、亀井尚、山本雅之
- Organizer
  日本生化学会東北支部第87 回例会・シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07395
[Presentation] Nrf2-Keap1生体防御システムの機能とその破綻による病態の解明2020
- Author(s)
  田口恵子
- Organizer
  第402回東北医学会例会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07395
[Presentation] ラットモデルを用いたNrf2活性化が引き起こす病態の解明2020
- Author(s)
  田口恵子、山本雅之
- Organizer
  第19回分子予防環境医学研究会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07395
[Presentation] Aflatoxin B1 induces fibrosis and cirrhosis in Nrf2 knockout rats2019
- Author(s)
  Keiko Taguchi, Nanae Osanai, Eriko Naganuma, Thomas W. Kensler, Masayuki Yamamoto
- Organizer
  58th Annual Meeting of Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Keap1-Nrf2 system: Findings using animal models2019
- Author(s)
  Keiko Taguchi
- Organizer
  National Institute on Aging/National Institute of Health (NIA/NIH) seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Unveiling new roles of Keap1-Nrf2 System by using rat models2019
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  The Environmental Response V
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07395
[Presentation] Keap1欠失ラットは転写因子Nrf2の活性化により重篤な肝障害を引き起こす2019
- Author(s)
  田口恵子、小山内七重、佐藤由莉、宮坂佳樹、真下知士、山本雅之
- Organizer
  平成30年度先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Nrf2 activation-acquired Liver cancer2017
- Author(s)
  Keiko Taguchi
- Organizer
  Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
- Place of Presentation
  ピッツバーグ・アメリカ
- Year and Date
  2017-03-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] 毒性学における転写因子Nrf2の貢献2017
- Author(s)
  田口恵子、山本雅之
- Organizer
  第44回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Simultaneous activation of K-ras and Nrf2 induce pancreatic atrophy2017
- Author(s)
  Hamada Shin, Masamune Atsushi, Taguchi Keiko, Yamamoto Masayuki and Shimosegawa Tooru
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04804
[Presentation] 毒性学におけるNrf2欠失ラットの貢献2017
- Author(s)
  田口恵子、山本雅之
- Organizer
  第10回ラットリソースリサーチ研究会
- Place of Presentation
  京都大学芝蘭会館稲盛ホール（京都）
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Nrf2 activation-acquired Liver cancer2017
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] The Nrf2 knockout rat as a toxicological tool2017
- Author(s)
  Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
- Organizer
  Society of Toxicology 56th Annual Meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] 毒性学におけるNrf2欠失ラットの貢献2017
- Author(s)
  田口恵子、山本雅之
- Organizer
  第10回ラットリソースリサーチ研究会
- Place of Presentation
  京都大学芝蘭会館稲盛ホール（京都）
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 activation-acquired Liver cancer2017
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  Closed seminar at Profs. Bruce Freeman & Thomas Kensler’s laboratories in University of Pittsburgh
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2017-03-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] 毒性学におけるNrf2欠失ラットの貢献2017
- Author(s)
  田口恵子、山本雅之
- Organizer
  第10回ラットリソースリサーチ研究会
- Place of Presentation
  京都大学芝蘭会館稲盛ホール（京都）
- Year and Date
  2017-02-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Pten欠失肝臓がんにおけるNrf2活性獲得の意義2017
- Author(s)
  田口恵子、一戸理沙、山本雅之
- Organizer
  第5回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] オートファジーとKeap1-Nrf2システム2017
- Author(s)
  田口恵子
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Nrf2 knockout suppresses pancreatic carcinogenesis in a mouse model2017
- Author(s)
  Shin Hamada, Atsushi Masamune, Keiko Taguchi, Masayuki Yamamoto, Tooru Shimosegawa
- Organizer
  Digestive Disease Week
- Place of Presentation
  San Diego, USA
- Year and Date
  2017-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04804
[Presentation] Nrf2 activation acquired in a transition from steatosis to liver cancer2017
- Author(s)
  Keiko Taguchi, Risa Ichinohe, Masayuki Yamamoto
- Organizer
  2017 International Congress Obesity and Metabolic Syndrome (ICOMES2017)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Nrf2 activation acquired in a transition from steatosis to liver cancer2017
- Author(s)
  Keiko Taguchi, Risa Ichinohe, Masayuki Yamamoto
- Organizer
  2017 International Congress Obesity and Metabolic Syndrome (ICOMES2017)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] The Nrf2 knockout rat as a toxicological tool2017
- Author(s)
  Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
- Organizer
  56th Annual Meeting of Society of Toxicology
- Place of Presentation
  Baltimore, Maryland, USA
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] オートファジーとKeap1-Nrf2システム2017
- Author(s)
  田口恵子
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016
- Author(s)
  田口恵子、増井紗帆、山本雅之
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウィンクあいち（名古屋）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016
- Author(s)
  田口恵子、増井紗帆、山本雅之
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウィンクあいち（名古屋）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016
- Author(s)
  田口恵子、小松雅明、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016
- Author(s)
  田口恵子、小松雅明、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（仙台）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略2016
- Author(s)
  田口恵子、鈴木隆史、山本雅之
- Organizer
  第10回オートファジー研究会・第4回新学術「オートファジー」班会議
- Place of Presentation
  NASPA ニューオータニ（新潟県越後湯沢）
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016
- Author(s)
  Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2の恒常的活性化はヘム合成阻害剤による肝毒性を軽減する2016
- Author(s)
  田口恵子、増井紗帆、山本雅之
- Organizer
  第43回日本毒性学会学術年会
- Place of Presentation
  ウィンクあいち（愛知県名古屋）
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] オートファジーの破綻による肝腫瘍とKeap1-Nrf2システム2016
- Author(s)
  田口恵子、小松雅明、山本雅之
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略2016
- Author(s)
  田口恵子、鈴木隆史、山本雅之
- Organizer
  第10回オートファジー研究会
- Place of Presentation
  NASPA ニューオータニ（越後湯沢）
- Year and Date
  2016-11-13
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016
- Author(s)
  Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
- Organizer
  41st NAITO Conference
- Place of Presentation
  CHATERAISE Gateaux Kingdom SAPPORO（札幌）
- Year and Date
  2016-07-05
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016
- Author(s)
  Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
- Organizer
  41st NAITO Conference
- Place of Presentation
  CHATERAISE Gateaux Kingdom SAPPORO（北海道札幌）
- Year and Date
  2016-07-05
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 activation in liver cancer model mice2016
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
- Place of Presentation
  Cagliari, Italy
- Year and Date
  2016-06-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Nrf2 activation in liver cancer model mice2016
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
- Place of Presentation
  カリアリ・イタリア
- Year and Date
  2016-06-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01190
[Presentation] Keiko Taguchi, Masayuki Yamamoto2016
- Author(s)
  Keiko Taguchi, Masayuki Yamamoto
- Organizer
  Closed seminar at Prof. Amedeo Columbano laboratory in University of Cagliari
- Place of Presentation
  Cagliari, Italy
- Year and Date
  2016-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 is a critical factor for hepatocellular adenoma in impaired autophagy2016
- Author(s)
  Keiko Taguchi, Masaaki Komatsu, Masayuki Yamamoto
- Organizer
  41st NAITO Conference
- Place of Presentation
  CHATERAISE Gateaux Kingdom SAPPORO（札幌）
- Year and Date
  2016-07-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0325
[Presentation] Nrf2はPten欠失による脂肪肝炎から肝臓がんの移行を促進する2015
- Author(s)
  田口恵子、一戸理沙、山本雅之
- Organizer
  第88回日本生化学会/第３８回日本分子生物学会合同大会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] 2つのタンパク質分解系による統合的なNrf2の制御メカニズム2015
- Author(s)
  田口恵子
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸国際会場（神戸）
- Year and Date
  2015-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2欠失ラットはアフラトキシンB1による肝毒性に対して脆弱である2015
- Author(s)
  田口恵子、高久美咲、Thomas W. Kensler、山本雅之
- Organizer
  第42回日本毒性学会学術年会
- Place of Presentation
  石川県立音楽堂，金沢市アートホール、ホテル日航金沢（金沢）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] A new tool for toxicology: Nrf2 knockout rat2015
- Author(s)
  Keiko Taguchi, Misaki Takaku, Masayuki Yamamoto
- Organizer
  The 7th International Congress of Asian Society of Toxicology (ASIATOX2015)
- Place of Presentation
  Jeju, Korea
- Year and Date
  2015-06-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 Knockout Rat Is Sensitive to Aflatoxin B1 Hepatotoxicity2015
- Author(s)
  Keiko Taguchi, Misaki Takaku, Patricia A. Egner, Thomas W. Kensler, Masayuki Yamamoto
- Organizer
  University of Pittsburgh Cancer Institute (UPCI) Scientific Retreat
- Place of Presentation
  Pittsburgh, USA
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] タンパク質分解によるNrf2活性制御メカニズム2015
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（神戸）
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 はPten 欠失による脂肪肝炎から肝がんへの移行を促進する2015
- Author(s)
  田口恵子、一戸理沙、山本雅之
- Organizer
  第３回がんと代謝研究会・金沢大学がん進展制御研究所共同利用・共同研究拠点シンポジウム
- Place of Presentation
  石川県立音楽堂交流ホール（金沢）
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] 肝毒性物質に応答した肝保護にはたらくNrf2の役割2014
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部第80回例会・シンポジウム
- Place of Presentation
  アキタパークホテル
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
- Organizer
  The Environmental Response IV
- Place of Presentation
  Katahira Sakura Hall (Sendai)
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Nrf2の活性制御破綻がもたらす肝病態2014
- Author(s)
  田口恵子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Gyeonggi Institute of Science & Technology Promotion
- Place of Presentation
  Gyeonggi Institute of Science & Technology Promotion, Suwon, Korea
- Year and Date
  2014-06-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 写因子Nrf2はPten欠損肝臓において胆管増生を促進する2014
- Author(s)
  6. 田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  加齢医学研究所第141回集談会
- Place of Presentation
  仙台
- Year and Date
  2014-01-17
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  2014 International Symposium and Annual Meeting of The Korean Society for Applied Biological Chemistry
- Place of Presentation
  Haeundae Grand Hotel (Busan, Korea)
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] 肝毒性物質に応答した肝保護にはたらくNrf2の役割2014
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部第80回例会・シンポジウム
- Place of Presentation
  アキタパークホテル（秋田）
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
- Organizer
  The Environmental Response IV
- Place of Presentation
  Katahira Sakura Hall (Sendai)
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers2014
- Author(s)
  1. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The Environmental Response IV
- Place of Presentation
  sendai
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2の活性制御破綻がもたらす肝病態2014
- Author(s)
  田口恵子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] PtenとKeap1 - Nrf2システムの破綻が引き起こす肝病態の解析2014
- Author(s)
  2. 田口恵子、本橋ほづみ、鈴木聡、山本雅之
- Organizer
  平成25年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する2014
- Author(s)
  5. 田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究修飾シグナル病領域推進会議 (15)
- Place of Presentation
  白金台
- Year and Date
  2014-01-25
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] PtenとKeap1-Nrf2システムの破綻が引き起こす肝病態の解析2014
- Author(s)
  田口恵子、本橋ほづみ、鈴木聡、山本雅之
- Organizer
  平成25年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琵琶湖ホテル（大津）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  2014 International Symposium and Annual Meeting of the KSABC (The Korean Society for Applied Biological Chemistry
- Place of Presentation
  Haeundae Grand Hotel, Busan, Korea
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Molecular Mechanisms and Functions of Keap1-Nrf2 system2014
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Gyeonggi Institute of Science & Technology Promotion
- Place of Presentation
  Gyeonggi Institute of Science & Technology Promotion (Suwon, Korea)
- Year and Date
  2014-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] PtenとKeap1-Nrf2システムの破綻が引き起こす肝病態の解析2014
- Author(s)
  田口恵子、本橋ほづみ、鈴木聡、山本雅之
- Organizer
  平成25年度個体レベルでのがん研究支援活動ワークショップ
- Place of Presentation
  琵琶湖ホテル（大津）
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013
- Author(s)
  田口恵子，本橋ほづみ，伊藤暢，田中稔，宮島篤，山本雅之
- Organizer
  フォーラム2013：衛生薬学・環境トキシコロジー
- Place of Presentation
  九州大学（博多）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2 enhances a hepatotoxin-induced hepatic cell expansion2013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
- Organizer
  The XIII International Congress of Toxicology (ICT2013)
- Place of Presentation
  Coex, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 転写因子Nrf2の制御破綻が引き起こす肝病態2013
- Author(s)
  12. 田口恵子
- Organizer
  平成25年度がん研究分野の特性等を踏まえた支援活動公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2013-08-22
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013
- Author(s)
  田口恵子，本橋ほづみ，伊藤暢，田中稔，宮島篤，山本雅之
- Organizer
  フォーラム2013：衛生薬学・環境トキシコロジー
- Place of Presentation
  九州大学（博多）
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013
- Author(s)
  13. 田口恵子、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究修飾シグナル病領域推進会議
- Place of Presentation
  白金台
- Year and Date
  2013-07-05
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] オートファジーによるKeaplタンパク質分解とレドックス恒常性維持2013
- Author(s)
  3. 田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  GCOEシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013
- Author(s)
  田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Two distinct mechanisms for degradation of a transcription factor Nrf22013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The 35th NAITO Conference
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京大学医科学研究所／東京
- Year and Date
  2013-02-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Nrf2 enhances a hepatotoxin - induced hepatic cell expansion2013
- Author(s)
  15. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The XIII International Congress of Toxicology(ICT2013)
- Place of Presentation
  Seoil, Korea
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013
- Author(s)
  田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  新学術研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  伊香保温泉
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝疾患における転写因子Nrf2の機能変化2013
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver, 1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling2013
- Author(s)
  4. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The Auditorium, The Institute of Medical Science
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 酸化ストレス応答機構Keap1 - Nrf2システムと肝病態2013
- Author(s)
  10. 田口恵子
- Organizer
  第12回生物化学若手研究者セミナー酸化ストレスに応答機構研究の展開
- Place of Presentation
  仙台
- Year and Date
  2013-09-07
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Two distinct mechanisms for degradation of a transcription factor Nrf22013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The 35th NAITO Conference
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013
- Author(s)
  田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
- Organizer
  第86回日本生化学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝疾患における転写因子Nrf2の機能変化2013
- Author(s)
  14. 田口恵子
- Organizer
  新学術領域研究修飾シグナル病領域推進会議
- Place of Presentation
  白金台
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝疾患における転写因子Nrf2の機能変化2013
- Author(s)
  田口恵子
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013
- Author(s)
  7. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
- Organizer
  新学術研究修飾シグナル病若手ワークショップ
- Place of Presentation
  伊香保
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] オートファジーによるKeap1タンパク質分解とレドックス恒常性維持2013
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  GCOEシンポジウム　～Network Medicineによる医学・生命科学の新たな潮流～
- Place of Presentation
  艮陵会館／仙台
- Year and Date
  2013-02-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013
- Author(s)
  8. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
- Organizer
  フォーラム2013 : 衛生薬学・環境トキシコロジー
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝疾患におけるNrf2の機能解析2013
- Author(s)
  11. 田口恵子
- Organizer
  第6回レドックス・ライフイノベーション第170委員会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 門脈枝結紮による代償的肝肥大におけるNrf2の役割2013
- Author(s)
  田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  新学術研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  伊香保温泉
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2 enhances a hepatotoxin-induced hepatic cell expansion2013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi and Masayuki Yamamoto
- Organizer
  The XIII International Congress of Toxicology (ICT2013)
- Place of Presentation
  Coex, Seoul, Korea
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] eciprocal activation between Nrf2 and a proliferative signaling in liver2013
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京大学医科学研究所／東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献2013
- Author(s)
  9. 田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
- Organizer
  第86回日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2 system for maintenance of redox homeostasis2012
- Author(s)
  Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The 6th International Congress of Asian Society of Toxicology (ASIATOX-VI)
- Place of Presentation
  仙台国際会議場／仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] PI3K経路により変化する転写因子Nrf2の機能2012
- Author(s)
  19. 田口恵子
- Organizer
  がん・エピゲノム研究会
- Place of Presentation
  仙台
- Year and Date
  2012-10-24
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012
- Author(s)
  17. 田口恵子、本橋ほづみ、山本雅之
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012
- Author(s)
  18. 田口恵子、本橋ほづみ、山本雅之
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1 Degradation by Autophagy for the Maintenance of Redox Homeostasis2012
- Author(s)
  Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  UK-Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  つくばサイエンスインフォメーションセンター／つくば
- Year and Date
  2012-04-06
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] 肝臓における２つのNrf2活性制御機構と胆管形成2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋観光ホテル／名古屋
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Crosstalk between Keap1-Nrf2 system and Pten-PI3K-Akt signaling regulates cellular proliferation and differentiation2012
- Author(s)
  Keiko Taguchi, Hozumi Motohashi , Masayuki Yamamoto
- Organizer
  The 33rd NAITO Conference “Oxygen Biology: Hypoxia, Oxidative Stress and Diseases”
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ／札幌
- Year and Date
  2012-06-26
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Keap1 Degradation by Autophagy for the Maintenance of Redox Homeostasis2012
- Author(s)
  Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  UK-Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  つくばサイエンスインフォメーションセンター／つくば
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  GCOE冬の合宿2012
- Place of Presentation
  秋保温泉
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] Crosstalk between Keap1-Nrf2 system and Pten-PI3K-Akt signaling regulates cellular proliferation and differentiation2012
- Author(s)
  Keiko Taguchi, Hozumi Motohashi , Masayuki Yamamoto
- Organizer
  The 33rd NAITO Conference “Oxygen Biology: Hypoxia, Oxidative Stress and Diseases”
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ／札幌
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝臓における２つのNrf2活性制御機構と胆管形成2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場／福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] PI3K経路により変化する転写因子Nrf2の機能2012
- Author(s)
  田口恵子
- Organizer
  がん・エピゲノム研究会
- Place of Presentation
  艮陵会館／仙台
- Year and Date
  2012-10-24
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Keap1-Nrf2システムとPI3K-Akt経路のクロストークと肝病態2012
- Author(s)
  田口恵子，本橋ほづみ，山本雅之
- Organizer
  2012年度新学術領域「転写代謝システム」班会議
- Place of Presentation
  つくばグランドホテル／つくば
- Year and Date
  2012-07-02
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  GCOE冬の合宿2012
- Place of Presentation
  秋保(宮城)
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Keap1 - Nrf2システムとPten - PI3K - Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012
- Author(s)
  25. 田口恵子、本橋ほづみ、山本雅之
- Organizer
  GCOE冬の合宿2012
- Place of Presentation
  秋保
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2012
- Author(s)
  16. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Kumamoto University Core Research Project B "Center for Frontier Research on Life Style an Stress Signal" and Grants-in-Aid for Scientific Research on Innovative Areas(Research in a Proposed Research Area), MEXT, Japan "Signaling Functions of Reactive Oxygen Species" Joint Symposium
- Place of Presentation
  Kumamoto
- Year and Date
  2012-12-18
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2システムとPI3K-Akt経路のクロストークと肝病態2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  2012年度新学術領域「転写代謝システム」班会議
- Place of Presentation
  つくばグランドホテル／つくば
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in metabolic reprogramming2012
- Author(s)
  Mitsuishi Y, Taguchi K, Aburatani H, Yamamoto M, Motohashi H
- Organizer
  Keystone Symposium on Cancer and Metabolism
- Place of Presentation
  アルバータ、カナダ
- Year and Date
  2012-02-12
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] レドックス恒常性維持に重要なオートファジーによるKeaplタンパク質の分解2012
- Author(s)
  20. 田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  2012年度新学術領域研究修飾シグナル病若手ワークショップ
- Place of Presentation
  湯河原
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keapl - Nrf3 system for maintenance of redox homeostasis2012
- Author(s)
  21. Keiko Taguchi, Nanako Fu j ikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Symposium Molecular toxicology: update, AS3 - 4, The 7th International Congress of Asian Society of Toxicology(ASIATOX-VI)
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 肝臓における２つのNrf2活性制御機構と胆管形成2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  フォーラム2012:衛生薬学・環境トキシコロジー
- Place of Presentation
  名古屋観光ホテル／名古屋
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] レドックス恒常性維持に重要なオートファジーによるKeap1タンパク質の分解2012
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  2012年度新学術領域研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  ホテルあかね／湯河原
- Year and Date
  2012-10-03
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2012
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Kumamoto University Core Research Project B and Grants-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area), MEXT, Japan Joint Symposium
- Place of Presentation
  アークホテル熊本城前／熊本
- Year and Date
  2012-12-18
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] 肝臓における２つのNrf2活性制御機構と胆管形成2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2 system for maintenance of redox homeostasis2012
- Author(s)
  Keiko Taguchi, Nanako Fujikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The 6th International Congress of Asian Society of Toxicology (ASIATOX-VI)
- Place of Presentation
  仙台国際会議場／仙台
- Year and Date
  2012-07-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Keap1 - Nrf2システムとPI3K - Akt経路のクロストークと肝病態2012
- Author(s)
  24. 田口恵子、本橋ほづみ、山本雅之
- Organizer
  2012年度新学術領域転写代謝システム班会議
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  GCOE冬の合宿2012
- Place of Presentation
  秋保
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keapl Degradation by Autophagy for the Maintenance of Redox Homeostasis2012
- Author(s)
  23. Keiko Taguchi, Nanako Fu j ikawa, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  UK - Japan Research Exchange Symposium Molecular Mechanisms of Stress Response in Disease
- Place of Presentation
  Tsukuba
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] レドックス恒常性維持に重要なオートファジーによるKeap1タンパク質の分解2012
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  2012年度新学術領域研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  ホテルあかね／湯河原
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Crosstalk between Keapl - Nrf2 system and Pten - PI3K-Akt signaling regulates cellular proliferation and differentiation2012
- Author(s)
  22. Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  The 33rd NAITO Conference Oxygen Biology : Hypoxia, Oxidative Stress and Diseases"
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  GCOE冬の合宿2012
- Place of Presentation
  秋保(宮城)
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] Co-activation of Nrf2 and Akt causes bile ductal metaplasia2011
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Tohoku University Global COE for conquest of Signal Transduction Diseases with "Network Medicine" Network Medicine Winter Camp of GCOE
- Place of Presentation
  宮城県秋保
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] 転写因子Nrf2欠損はウレタン誘導性肺発癌を減少させ、Nrf2欠損癌組織は免疫不全マウスで著しい生着不全と増殖能低下をきたす2011
- Author(s)
  佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011
- Author(s)
  田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] マウス遺伝学解析に基盤とするKeap1-Nrf2システムの解明2011
- Author(s)
  山本雅之、鈴木隆史、田口恵子、本橋ほづみ
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011
- Author(s)
  Nanako Fujikawa, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Hotel Rodos Palace, Rhodes Island in Greece
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] レドックス恒常性維持に重要なKeap1分解機構の解明2011
- Author(s)
  藤川奈々子、田口恵子、本橋ほづみ、山本雅之
- Organizer
  平成23年度がん若手ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011
- Author(s)
  Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  ギリシャ・ロードス島
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] Keap1-Nrf2システムとAktシグナルの相互作用と肝疾患2011
- Author(s)
  田口恵子, 本橋ほづみ, 山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in proliferating cells2011
- Author(s)
  Yoichiro Mitsuishi, Keiko Taguchi, Masayuki Yamamoto, Hozumi Motohashi
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011
- Author(s)
  Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  ギリシャ・ロードス島
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] Transcription factor Nrf2 drives the pentose phosphate pathway and glutamine consumption in proliferating cells2011
- Author(s)
  Yoichiro Mitsuishi, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Discovery on Target ; Cancer Cell Metabolism as Drug Target
- Place of Presentation
  Boston, USA
- Year and Date
  2011-11-02
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011
- Author(s)
  田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PUBLICLY-23117503
[Presentation] 転写因子Nrf2はペントースリン酸経路とグルタミン代謝を制御して細胞増殖に貢献する2011
- Author(s)
  光石陽一郎、田口恵子、油谷浩幸、貫和敏博、本橋ほづみ、山本雅之
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011
- Author(s)
  田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
- Organizer
  フォーラム2011:衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011
- Author(s)
  Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
- Organizer
  16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
- Place of Presentation
  Rhodes Island, Greece
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 上皮細胞における転写因子Nrf2の活性化2010
- Author(s)
  田口恵子、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  フォーラム2010:衛生薬学・環境トキシコロジー
- Place of Presentation
  星薬科大学
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] Co-activation of Nrf2 and Akt causes bile ductal metaplasia2010
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Tohoku University Global COE for conquest of Signal Transduction Diseases with"Network Medicine", Network Medicine Winter Camp of GCOE
- Place of Presentation
  Akiu, Miyagi
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] 上皮細胞における転写因子Nrf2の活性化2010
- Author(s)
  田口恵子、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  日本生化学会東北支部会第76回例会・シンポジウム
- Place of Presentation
  福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 転写因子Nrf2は宿主肺における癌転移抑制因子である2010
- Author(s)
  佐藤大希、田口恵子、森口尚、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第50回日本呼吸器学会学術総会
- Place of Presentation
  湯沢
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 宿主におけるNrf2欠損はMDSCs細胞に著明な酸化ストレスの蓄積を誘導し、肺癌転移に対して有利な微小環境を創造する2010
- Author(s)
  佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] 上皮細胞における転写因子Nrf2の活性化2010
- Author(s)
  田口恵子、鈴木隆史、本橋ほづみ、山本雅之
- Organizer
  第76回日本生化学会東北支部会例会
- Place of Presentation
  コラッセ福島
- Year and Date
  2010-05-08
- Data Source
  KAKENHI-PROJECT-22790127
[Presentation] Nrf2 acts as a novel metastasis suppressor in the lung2009
- Author(s)
  Satoh H, Taguchi K, Moriguchi T, Suzuki T, Ebina M, Nukiwa T, Yamamoto M.
- Organizer
  68回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] New function of host NRF2 in lung cancer2009
- Author(s)
  佐藤大希, 田口恵子, 森口尚, 鈴木隆史, 海老名雅仁, 貫和敏博, 山本雅之
- Organizer
  Interdisciplinary Force 学生成果発表会
- Place of Presentation
  仙台
- Year and Date
  2009-08-04
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] Cell tyte-specific Nrf2 activation : different feature in hepatocytes and epithelial cells2009
- Author(s)
  Taguchi K, Yamamoto M.
- Organizer
  CDBIM symposium
- Place of Presentation
  東京
- Year and Date
  2009-10-26
- Data Source
  KAKENHI-PROJECT-19GS0312
[Presentation] PI3K経路により変化する転写因子Nrf2の機能
- Author(s)
  田口恵子
- Organizer
  がん・エピゲノム研究会
- Place of Presentation
  艮陵会館／仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Kumamoto University Core Research Project B and Grants-in-Aid for Scientific Research on Innovative Areas (Research in a Proposed Research Area), MEXT, Japan Joint Symposium
- Place of Presentation
  アークホテル熊本城前／熊本
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Establishment and characterization of Nrf2 knockout rats
- Author(s)
  Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
- Organizer
  2nd International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京大学医科学研究所（白金台）（東京）
- Year and Date
  2015-01-23 – 2015-01-24
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する
- Author(s)
  田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Multi-step regulation of Nrf2 activity in the liver
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Japan/Korea Joint Symposium on Pharmaceutical Health Science and Environmental Toxicology
- Place of Presentation
  つくば国際会議場
- Year and Date
  2014-09-19 – 2014-09-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 酸化ストレス応答機構Keap1-Nrf2システムと肝病態
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  第１２回生物化学若手研究者セミナー
- Place of Presentation
  東北薬科大学（仙台）
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Nrf2は門脈枝結紮による代償的肝肥大を促進する
- Author(s)
  田口恵子、白崎圭一、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 転写因子Nrf2の活性制御メカニズムと病態
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  若手放射線生物学研究会勉強会
- Place of Presentation
  京都大学原子炉実験所
- Year and Date
  2014-08-08 – 2014-08-10
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 転写因子Nrf2はPten欠損肝臓において胆管増生を促進する
- Author(s)
  田口恵子、山本雅之、本橋ほづみ
- Organizer
  加齢医学研究所第141回集談会
- Place of Presentation
  東北大（仙台）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] 転写因子Nrf2の活性制御メカニズムと病態
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  若手放射線生物学研究会勉強会
- Place of Presentation
  京都大学原子炉実験所（大阪）
- Year and Date
  2014-08-08 – 2014-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] 酸化ストレス応答機構Keap1-Nrf2システムと肝病態
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  第１２回生物化学若手研究者セミナー
- Place of Presentation
  東北薬科大学（仙台）
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] オートファジーによるKeap1タンパク質分解とレドックス恒常性維持
- Author(s)
  田口恵子、藤川奈々子、本橋ほづみ、山本雅之
- Organizer
  GCOEシンポジウム　～Network Medicineによる医学・生命科学の新たな潮流～
- Place of Presentation
  艮陵会館／仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Establishment and characterization of Nrf2 knockout rats
- Author(s)
  Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
- Organizer
  Biochemical Society-The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Robinson College, Cambridge, UK
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] Establishment and characterization of Nrf2 knockout rats
- Author(s)
  Keiko Taguchi, Misaki Takaku, Masanobu Morita, Masayuki Yamamoto
- Organizer
  Biochemical Society-The Keap1/Nrf2 Pathway in Health and Disease
- Place of Presentation
  Robinson College, Cambridge, UK
- Year and Date
  2015-01-06 – 2015-01-08
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Liver diseases caused by perturbation of Nrf2 regulation
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 転写因子Nrf2はPten欠損肝臓において胆管増生を促進する
- Author(s)
  田口恵子、山本雅之、本橋ほづみ
- Organizer
  加齢医学研究所第141回集談会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PUBLICLY-25117703
[Presentation] 肝毒性物質による肝肥大におけるNrf2の貢献
- Author(s)
  田口恵子、本橋ほづみ、山本雅之
- Organizer
  新学術領域研究「修飾シグナル病」領域推進会議
- Place of Presentation
  東京大学医科学研究所（白金台）
- Data Source
  KAKENHI-PROJECT-24790307
[Presentation] Multi-step regulation of Nrf2 activity in the liver
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  Japan/Korea Joint Symposium on Pharmaceutical Health Science and Environmental Toxicology
- Place of Presentation
  つくば国際会議場（つくば）
- Year and Date
  2014-09-19 – 2014-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460384
[Presentation] Liver diseases caused by perturbation of Nrf2 regulation
- Author(s)
  Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460384
[]
[]

1. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 42 results
2. SUZUKI Takafumi (70508308)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. Masamune Atsushi (90312579)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. 濱田晋 (20451560)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
5. KATSUOKA Fumiki (30447255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. MINEGISHI Naoko (40271895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MOTOHASHI Hozumi (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
8. KUROKAWA Hirofumi (80359546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. SUZUKI Norio (20447254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
10. MORIGUCHI Takashi (10447253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 赤池孝章 (20231798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Kensler Thomas W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. Columbano Amedeo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Cuadrado Antonio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANAKA Minoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. ITOH Tohru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 宮島篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 丸山和一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 宮崎陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 石田典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Taguchi Keiko 田口 恵子

TAGUCHI Keiko 田口 恵子

Research Projects

Research Products

Co-Researchers

肝臓の組織構築におけるNrf2の新たな機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

硫黄生物学から紐解く膵癌難治化機構の解明と治療応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of esophagus cancer acquired Nrf2 activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapy for pancreatic cancer based on the regulation of oxidative stress responses

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hepatic tumor and Nrf2 activation by impaired autophagy(Fostering Joint International Research)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

オートファジー破綻がもたらす病態のNrf2を標的とした治療戦略Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of oxidative stress response in pancreatic diseases and therapeutic application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hepatic tumor and Nrf2 activation by impaired autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝疾患における転写因子Nrf２の機能変化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Nrf2 in compensatory liver proliferation after portal vein branch ligation in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ｋｅａｐ１－Ｎｒｆ２システムとＡｋｔシグナルの相互作用と肝疾患Principal Investigator

Principal Investigator

Project Period (FY)

Taguchi Keiko 田口恵子

TAGUCHI Keiko 田口恵子