Sakai Kazuko 坂井和子

… Alternative Names

SAKAI Kazuko 坂井和子

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Researcher Number	20580559
Other IDs
Affiliation (Current)	2025: 近畿大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 近畿大学, 医学部, 講師 2012 – 2017: 近畿大学, 医学部, 助教 2016: 近畿大学, 医学部・ゲノム生物学教室, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnostics / Tumor diagnosis Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52010:General internal medicine-related / Otorhinolaryngology / Basic Section 55020:Digestive surgery-related / Basic Section 56030:Urology-related / Basic Section 49020:Human pathology-related / Basic Section 56040:Obstetrics and gynecology-related … More / Basic Section 56050:Otorhinolaryngology-related / Science and Engineering / Tumor diagnostics / Clinical oncology Less
Keywords	Principal Investigator セルフリーDNA / 次世代シーケンサー / 肺癌 / 血小板 / コピー数変化 / 遺伝子変異 / 肝細胞がん / 遺伝子異常 / 腫瘍内不均一性 / 肝細胞癌 … More / ALK融合遺伝子 / 融合遺伝子 / 非小細胞肺癌 / エキソソーム / 血しょう / 血漿 / 体細胞遺伝子変異 / 肺がん / バイオマーカー / 血清 / ＥＭＬ４－ＡＬＫ / 薬効評価と予測 … More Except Principal Investigator リキッドバイオプシー / 技能試験 / 外部精度評価 / 肺癌 / 次世代シーケンサー / 免疫チェックポイント阻害剤 / 免疫チェックポイント阻害薬 / 腸内細菌 / 次世代シークエンサー / 分子標的薬 / ゲノム解析 / バイオマーカー / HPV / 中咽頭癌 / 循環腫瘍DNA / メチル化 / 機械学習 / 原発不明癌 / プロセス管理 / ゲノム医療 / 質保証 / 血中遊離核酸検査 / 癌微小環境 / 縫合不全 / 腸管免疫 / 直腸癌 / 去勢抵抗性 / 前立腺がん / CRPC / Exosome / cfDNA / ARV7 / 4F2hc / L型アミノ酸トランスポーター / エクソソーム / Liquid Biopsy / LAT1 / LAT3 / アミノ酸トランスポーター / AI / テストステロン / 前立腺癌 / 臨床検査の質保証 / EQA / ISO 17043 / 循環血中腫瘍由来DNA / バイオインフォマティクス / DNAの品質 / がんゲノム医療 / 検査の質保証 / がん遺伝子パネル検査 / 免疫不全リンパ腫 / エプスタインーバーウイルス / 関節リウマチ / リンパ増殖性疾患 / メトトレキサート / ジャポニカアレイ / SNP / 統合的解析 / トランスクリプトーム解析 / lymphoma / DLBCL / interferon-γ / Epstein Barr Virus / RNA transpcriptome / RA-LPD / MTX-LPD / GWAS / RNA transcriptome / Methotrexate / LPD / Rheumatoid arthritis / 抗PD-1抗体 / 遺伝子発現 / 臨床腫瘍 / 次世代シーケンサー（NGS） / 薬物治療アクセス割合 / 機能解析 / VUS / ドライバー遺伝子 / 遺伝子パネル / 化学療法感受性 / 機能ゲノミクス解析 / 相同組み替え修復 / オミックス解析 / 免疫療法 / ゲノム / DNA修復機構 / 幹細胞 / 腫瘍免疫 / 腫瘍内不均一性 / 卵巣癌 / リスク / 低侵襲治療 / 遺伝子解析 / 抗PD-1 / 化学コミュニケーション / 肝細胞癌 / 大腸癌 / 宿主 / 細菌叢 / メタトランスクリプトーム / 相互作用 / 大腸がん / アルツハイマー病 / 多発性硬化症 / CMG / NMN / 免疫関連有害事象irAE / 大腸がん相互作用 / 中枢神経炎症疾患 / 腸内細菌叢 / エンリッチメント解析 / 免疫関連有害事象 / 中枢神経炎 / 炎症性腸疾患 / MET / AKT / アファチニブ / ヘレグリン / HER3 / 薬効評価と予測 / 遺伝子異常 / 免疫染色 / 唾液腺癌 / 唾液腺腺癌 / 唾液腺導管癌 / 遺伝子変異 / 唾液腺がん / ＨＰＶ / 中咽頭がん / 集学的治療 / EML4-ALK融合遺伝子 / EGFR遺伝子変異 / 分子標的治療 / 非小細胞肺癌 Less

Evaluation of minimal residual disease in postoperative lung cancer using platelet RNA influenced by the tumor environment.Principal Investigator
- Principal Investigator
  
  坂井和子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
血中遊離核酸検査の質保証と技能試験の開発；精確な結果に基づくゲノム医療をめざして
- Principal Investigator
  
  前川真人
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Hamamatsu University School of Medicine
Validation study of a model for estimating the primary organ of cancer of unknown primary by methylation analysis of circulating tumor DNA
- Principal Investigator
  
  西尾和人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
直腸癌術後縫合不全発症における腸管免疫・腸内細菌を含む微小環境変化の解析
- Principal Investigator
  
  川村純一郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kindai University
Functional analysis of novel responsible genes for methotrexate-related lymphoproliferative disease toward genomic medicine
- Principal Investigator
  
  Hoshida Yoshihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Hospital Organization Osaka-Minami Medical Center
To improve quality of cancer gene panel tests by strategic implementation of external quality assessment scheme
- Principal Investigator
  
  MAEKAWA Masato
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Hamamatsu University School of Medicine
Establishment of aminoacid transporter directed prostate cancer therapy based on the liquid biopsy
- Principal Investigator
  
  Sakamoto Shinichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Chiba University
Functional analysis of novel gene mutation identified in clinical sequencing
- Principal Investigator
  
  Takeda Masayuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nara Medical University
  Kindai University
Investigation of molecular pathology based on quantitative evaluation of intratumor heterogeneity in hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Sakai Kazuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
Immune related gene-expression profiling for the combination of chemotherapy and PD-1/PD-L1 inhibition.
- Principal Investigator
  
  HAYASHI Hidetoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kindai University
Development of minimally invasive treatment based on risk assessment for HPV-mediated oropharyngeal carcinomas
- Principal Investigator
  
  YANE Katsunari
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Kindai University
Development of new treatment for ovarian cancer based on intratumor heterogeneity
- Principal Investigator
  
  Matsumura Noriomi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kindai University
Investigation for a mechanism of cetuxifmab resistance in head and neck cancers
- Principal Investigator
  
  YONESAKA Kimio
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kindai University
Chemical communication between human and microflora in inflammatory bowel disease, carcinogenesis, and cancer immunity
- Principal Investigator
  
  Nishio Kazuto
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kindai University
Detection of ALK fusion genes in plasma exosomesPrincipal Investigator
- Principal Investigator
  
  SAKAI Kazuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kindai University
Development of biomarkers for multimodality treatment aimed at function preservation in head and neck cancer
- Principal Investigator
  
  YANE Katsunari
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kindai University
Liquid biopsy for detection of somatic mutation using next generation sequencerPrincipal Investigator
- Principal Investigator
  
  SAKAI Kazuko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kinki University
Exploratory analyses of immunohistochemistry pattern and genetic alterations for salivary gland cancer
- Principal Investigator
  
  Kiyota Naomi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kobe University
Multiplex molecular profiling in advanced non-small cell lung cancers
- Principal Investigator
  
  OKAMOTO Isamu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kyushu University
  Kinki University
Detection of EML4-ALK in serum RNA from lung cancer patientsPrincipal Investigator
- Principal Investigator
  
  SAKAI Kazuko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kinki University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 Other

All Journal Article Presentation Book Other

[Book] 日本臨牀 75巻増刊号8号　がん転移学 (上)がん転移のメカニズムと治療戦略 : その基礎と臨床 - 序文 : 転移がん治療の進歩と課題「転移の分子診断」2017
- Author(s)
  西尾和人、坂井和子
- Total Pages
  305
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Soluble immune checkpoint factors reflect exhaustion of antitumor immunity and response to PD-1 blockade2024
- Author(s)
  Hayashi Hidetoshi, Chamoto Kenji, Hatae Ryusuke, Kurosaki Takashi, Togashi Yosuke, Fukuoka Kazuya, Goto Megumi, Chiba Yasutaka, Tomida Shuta, Ota Takayo, Haratani Koji, Takahama Takayuki, Tanizaki Junko, Yoshida Takeshi, Iwasa Tsutomu, Tanaka Kaoru, Takeda Masayuki, Hirano Tomoko, Sakai Kazuko, Nishio Kazuto, etc
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 134 Issue: 7
- DOI
  10.1172/jci168318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27468
[Journal Article] TP53 and/or BRCA1 Mutations Based on CtDNA Analysis as Prognostic Biomarkers for Primary Triple-Negative Breast Cancer2024
- Author(s)
  Arimura Akiko、Sakai Kazuko、Kaneshiro Kazuhisa、Morisaki Takafumi、Hayashi Saori、Mizoguchi Kimihisa、Yamada Mai、Kai Masaya、Ono Mayumi、Nishio Kazuto、Nakamura Masafumi、Kubo Makoto
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 6 Pages: 1184-1184
- DOI
  10.3390/cancers16061184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19532, KAKENHI-PROJECT-23K27468
[Journal Article] Copy Number Gain in Androgen Receptors Predicts the Poor Prognosis in Japanese Castration-resistant Prostate Cancer2024
- Author(s)
  SAKAMOTO SHINICHI、ANDO KEISUKE、PAE SANGJON、ZHAO XUE、SAKAI KAZUKO、SATO KODAI、SAITO SHINPEI、YAMADA YASUTAKA、RII JUNRYO、GOTO YUSUKE、SAZUKA TOMOKAZU、IMAMURA YUSUKE、ANZAI NAOHIKO、AKAKURA KOICHIRO、NISHIO KAZUTO、ICHIKAWA TOMOHIKO
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 2 Pages: 639
- DOI
  10.21873/anticanres.16853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19348, KAKENHI-PROJECT-21H03065, KAKENHI-PROJECT-23K27468
[Journal Article] Impact of ramucirumab plus erlotinib on circulating cell-free DNA from patients with untreated metastatic non-small cell lung cancer with EGFR-activating mutations (RELAY phase 3 randomized study)2023
- Author(s)
  Nishio Kazuto, Sakai Kazuko, Nishio Makoto, Seto Takashi, Visseren-Grul Carla, Carlsen Michelle, Matsui Tomoko, Enatsu Sotaro, Nakagawa Kazuhiko
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 12 Issue: 8 Pages: 1702-1716
- DOI
  10.21037/tlcr-22-736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K27468
[Journal Article] Patients with polyclonal hepatocellular carcinoma are at a high risk of early recurrence and have a poor recurrence-free survival period2022
- Author(s)
  Kaibori M, Sakai K, Matsushima H, Kosaka H, Matsui K, De Velasco MA, Sekimoto M, Nishio K.
- Journal Title
  
  Hepatol Int.
  
  Volume: 16 Issue: 1 Pages: 135-147
- DOI
  10.1007/s12072-021-10278-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07722
[Journal Article] Intestinal microbiota and gene expression reveal similarity and dissimilarity between immune-mediated colitis and ulcerative colitis.2021
- Author(s)
  Sakai, K., Sakurai, T., De Velasco MA., Nagai, T., Chikugo, T., Ueshima, K., Kura, Y., Takahama, T., Hayashi, H., Nakagawa, K., Kudo, M., *Nishio, K.
- Journal Title
  
  Front. Oncol
  
  Volume: 11 Pages: 763468-763468
- DOI
  10.3389/fonc.2021.763468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Frequent PIK3CA mutations in eutopic endometrium of patients with ovarian clear cell carcinoma2021
- Author(s)
  Murakami Kosuke、Kanto Akiko、Sakai Kazuko、Miyagawa Chiho、Takaya Hisamitsu、Nakai Hidekatsu、Kotani Yasushi、Nishio Kazuto、Matsumura Noriomi
- Journal Title
  
  Modern Pathology
  
  Volume: 34 Issue: 11 Pages: 2071-2079
- DOI
  10.1038/s41379-021-00861-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-20K21665
[Journal Article] A Novel Malignant Peritoneal Mesothelioma with STRN Exon 2 and ALK Exon 20: A Case Report and Literature Review.2021
- Author(s)
  Miyagawa C, Takaya H, Sakai K, Nishio K, Konishi M, Minamiguchi S, Shimada T, Matsumura N.
- Journal Title
  
  Oncologist
  
  Volume: - Issue: 5 Pages: 356-361
- DOI
  10.1002/onco.13714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947
[Journal Article] Integrative analysis of gut microbes and host transcriptomes reveals associations between treatment outcomes and immunotherapy-induced colitis.2021
- Author(s)
  Sakurai, T., De Velasco MA., Sakai, K., Nagai, T., Nishiyama, H., Hashimoto, K., Uemura, H., Kawakami, H., Nakagawa, K., Ogata, H., *Nishio, K., Kudo, M.
- Journal Title
  
  Mol. Oncol
  
  Volume: - Pages: 13062-13062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Transcriptome profiling and metagenomic analysis help to elucidate interactions in inflammatory-associated.2021
- Author(s)
  Sakai, K., De Velasco MA., Kura, Y., *Nishio, K.
- Journal Title
  
  Cancers (Basel).
  
  Volume: 13 Issue: 15 Pages: 3683-3683
- DOI
  10.3390/cancers13153683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Genetic profile of adult T‐cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV‐1 strains2021
- Author(s)
  Sakihama Shugo、Morichika Kazuho、Saito Rumiko、Miyara Megumi、Miyagi Takashi、Hayashi Masaki、Uchihara Junnosuke、Tomoyose Takeaki、Ohshiro Kazuiku、Nakayama Shingo、Nakachi Sawako、Morishima Satoko、Sakai Kazuko、Nishio Kazuto、Masuzaki Hiroaki、Fukushima Takuya、Karube Kennosuke
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 3 Pages: 1300-1309
- DOI
  10.1111/cas.14806
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-19K17835, KAKENHI-PROJECT-20K08912, KAKENHI-PROJECT-19K17862
[Journal Article] Clinical Application of the FoundationOne CDx Assay to Therapeutic Decision-Making for Patients with Advanced Solid Tumors2021
- Author(s)
  Takeda M, Takahama T, Sakai K, Shimizu S, Watanabe S, Kawakami H, Tanaka K, Sato C, Hayashi H, Nonagase Y, Yonesaka K, Takegawa N, Okuno T, Yoshida T, Fumita S, Suzuki S, Haratani K, Saigoh K, Ito A, Mitsudomi T, Handa H, Fukuoka K, Nakagawa K, Nishio K.
- Journal Title
  
  Oncologist
  
  Volume: 26(4) Issue: 4 Pages: e588-e596
- DOI
  10.1002/onco.13639
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07721
[Journal Article] Reclassification prediction of first-year protocol biopsy on active surveillance of prostate cancer by p2PSA-related parameters: from PRIAS-JAPAN2021
- Author(s)
  Kato Takuma、Hirama Hiromi、Mitsuzuka Koji、Maruyama Satoru、Sasaki Hiroshi、Saito Toshihiro、Matsumoto Ryuji、Sakamoto Shinichi、Sakai Yasuyuki、Fukuhara Hiroshi、Naya Yukio、Tsukino Hiromasa、Hara Isao、Ogawa Osamu、Hashine Katsuyoshi、Fumimasa Fukuta、Yokomizo Akira、Tohi Yoichiro、Kakehi Yoshiyuki、Sugimoto Mikio
- Journal Title
  
  Prostate Cancer and Prostatic Diseases
  
  Volume: 25 Issue: 4 Pages: 666
- DOI
  10.1038/s41391-021-00422-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-22K09510, KAKENHI-PROJECT-19K09720
[Journal Article] Site-Specific and Targeted Therapy Based on Molecular Profiling by Next-Generation Sequencing for Cancer of Unknown Primary Site: A Nonrandomized Phase 2 Clinical Trial2020
- Author(s)
  Hayashi, H. Takiguchi, Y. Minami, H. Akiyoshi, K. Segawa, Y. Ueda, H. Iwamoto, Y. Kondoh, C. Matsumoto, K. Takahashi, S. Yasui, H. Sawa, T. Onozawa, Y. Chiba, Y. Togashi, Y. Fujita, Y. Sakai, K. Tomida, S. Nishio, K. Nakagawa, K.
- Journal Title
  
  JAMA Oncol
  
  Volume: 6 Issue: 12 Pages: 1931-1938
- DOI
  10.1001/jamaoncol.2020.4643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08561, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-19K22574
[Journal Article] Association between Genetic and Immunological Background of Hepatocellular Carcinoma and Expression of Programmed Cell Death-12020
- Author(s)
  Nishida Naoshi、Sakai Kazuko、Morita Masahiro、Aoki Tomoko、Takita Masahiro、Hagiwara Satoru、Komeda Yoriaki、Takenaka Mamoru、Minami Yasunori、Ida Hiroshi、Ueshima Kazuomi、Nishio Kazuto、Kudo Masatoshi
- Journal Title
  
  Liver Cancer
  
  Volume: 9 Issue: 4 Pages: 426-439
- DOI
  10.1159/000506352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-18K07922
[Journal Article] Impact of coexisting gene mutations in EGFR-mutated non-small cell lung cancer before treatment on EGFR T790M mutation status after EGFR-TKIs.2020
- Author(s)
  Takeda M, Sakai K, Hayashi H, Tanaka K, Haratani K, Takahama T, Kato R, Yonesaka K, Nishio K, Nakagawa K.
- Journal Title
  
  Lung Cancer
  
  Volume: 139 Pages: 28-34
- DOI
  10.1016/j.lungcan.2019.10.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07721
[Journal Article] Refractory case of ulcerative colitis with idiopathic thrombocytopenic purpura successfully treated by Janus kinase inhibitor tofacitinib: A case report2020
- Author(s)
  Komeda Yoriaki、Sakurai Toshiharu、Sakai Kazuko、Morita Yasuyoshi、Hashimoto Arito、Nagai Tomoyuki、Hagiwara Satoru、Matsumura Itaru、Nishio Kazuto、Kudo Masatoshi
- Journal Title
  
  World Journal of Clinical Cases
  
  Volume: 8 Issue: 24 Pages: 6389-6395
- DOI
  10.12998/wjcc.v8.i24.6389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-20K08368
[Journal Article] Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts2020
- Author(s)
  Kato Ryoji、Haratani Koji、Hayashi Hidetoshi、Sakai Kazuko、Sakai Hitomi、Kawakami Hisato、Tanaka Kaoru、Takeda Masayuki、Yonesaka Kimio、Nishio Kazuto、Nakagawa Kazuhiko
- Journal Title
  
  British Journal of Cancer
  
  Volume: 124 Issue: 5 Pages: 914-924
- DOI
  10.1038/s41416-020-01201-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN with RS-T) complicated by hyperleukocytosis and gene analysis in relation to leukocytosis2019
- Author(s)
  Aoyama Y, Sakai K, Kodaka T, Tsunemine H, Nishio K, Itoh T, Inoue D, Takahashi T
- Journal Title
  
  Journal of Clinical and Experimental Hematopathology
  
  Volume: 59 Issue: 1 Pages: 29-33
- DOI
  10.3960/jslrt.18037
- NAID
  130007627903
- ISSN
  1346-4280, 1880-9952
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Clinical and immune profiling for cancer of unknown primary site.2019
- Author(s)
  Haratani K, Hayashi H, Takahama T, Nakamura Y, Tomida S, Yoshida T, Chiba Y, Sawada T, Sakai K, Fujita Y, Togashi Y, Tanizaki J, Kawakami H, Ito A, Nishio K, Nakagawa K
- Journal Title
  
  Journal for immunotherapy of cancer
  
  Volume: 7 Issue: 1 Pages: 251-251
- DOI
  10.1186/s40425-019-0720-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07049, KAKENHI-PROJECT-19K22574, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17K07204, KAKENHI-PROJECT-17K10784
[Journal Article] Intratumor heterogeneity and homologous recombination deficiency of high-grade serous ovarian cancer are associated with prognosis and molecular subtype and change in treatment course.2019
- Author(s)
  Takaya H, Nakai H, Sakai K, Nishio K, Murakami K, Mandai M, *Matsumura N.
- Journal Title
  
  Gynecol Oncol.
  
  Volume: 156 Issue: 2 Pages: 415-422
- DOI
  10.1016/j.ygyno.2019.11.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-18H02947
[Journal Article] aCGH Analysis of Predictive Biomarkers for Response to Bevacizumab plus Oxaliplatin- or Irinotecan-Based Chemotherapy in Patients with Metastatic Colorectal Cancer2019
- Author(s)
  Fujita Y, Taguri M, Yamazaki K, Tsurutani J, Sakai K, Tsushima T, Nagase M, Tamagawa H, Ueda S, Tamura T, Tsuji Y, Murata K, Taira K, Denda T, Moriwaki T, Funai S, Nakajima TE, Muro K, Tsuji A, Yoshida M, Suyama K, Kurimoto T, Sugimoto N, Baba E, Seki N, Sato M, Shimura T, Boku N, Hyodo I, Yamanaka T, Nishio K.
- Journal Title
  
  Oncologist.
  
  Volume: 24 Issue: 3 Pages: 327
- DOI
  10.1634/theoncologist.2018-0119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-17K07204, KAKENHI-PLANNED-17H06404
[Journal Article] Impact of cytotoxic chemotherapy on PD-L1 expression in patients with non-small cell lung cancer negative for EGFR mutation and ALK fusion.2019
- Author(s)
  Sakai H, Takeda M, Sakai K, Nakamura Y, Ito A, Hayashi H, Tanaka K, Nishio K, Nakagawa K.
- Journal Title
  
  Lung Cancer
  
  Volume: 127 Pages: 59-65
- DOI
  10.1016/j.lungcan.2018.11.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI2019
- Author(s)
  Yonesaka Kimio、Tanaka Kaoru、Kitano Mutsukazu、Kawakami Hisato、Hayashi Hidetoshi、Takeda Masayuki、Sakai Kazuko、Nishio Kazuto、Doi Katsumi、Nakagawa Kazuhiko
- Journal Title
  
  Oncogenesis
  
  Volume: 8 Issue: 10 Pages: 1-10
- DOI
  10.1038/s41389-019-0164-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07203
[Journal Article] Randomized Phase II Trial Comparing Site-Specific Treatment Based on Gene Expression Profiling With Carboplatin and Paclitaxel for Patients With Cancer of Unknown Primary Site2019
- Author(s)
  Hayashi Hidetoshi、Kurata Takayasu、Takiguchi Yuichi、Arai Makoto、Takeda Koji、Akiyoshi Kohei、Matsumoto Koji、Onoe Takuma、Mukai Hirofumi、Matsubara Nobuaki、Minami Hironobu、Toyoda Masanori、Onozawa Yusuke、Ono Akira、Fujita Yoshihiko、Sakai Kazuko、et al.
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 37 Issue: 7 Pages: 570-579
- DOI
  10.1200/jco.18.00771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07204, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-19H03907, KAKENHI-PROJECT-17K09647
[Journal Article] A randomized phase II trial of trastuzumab plus capecitabine versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer previously treated with trastuzumab and taxanes: WJOG6110B/ELTOP.2018
- Author(s)
  Takano T, Tsurutani J, Takahashi M, Yamanaka T, Sakai K, Ito Y, Fukuoka J, Kimura H, Kawabata H, Tamura K, Matsumoto K, Aogi K, Sato K, Nishio K, Nakagawa K, Saeki T.
- Journal Title
  
  Breast
  
  Volume: 40 Pages: 67-75
- DOI
  10.1016/j.breast.2018.04.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] An HER3-targeting antibody-drug conjugate incorporating a DNA topoisomerase I inhibitor U3-1402 conquers EGFR tyrosine kinase inhibitor-resistant NSCLC.2018
- Author(s)
  Yonesaka K, Takegawa N, Watanabe S, Haratani K, Kawakami H, Sakai K, Chiba Y, Maeda N, Kagari T, Hirotani K, Nishio K, Nakagawa K.
- Journal Title
  
  Oncogene
  
  Volume: 38(9) Issue: 9 Pages: 1398-1409
- DOI
  10.1038/s41388-018-0517-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Heterogeneity of EGFR-mutant clones and PD-L1 highly-expressing clones affects treatment efficacy of EGFR-TKI and PD-1 inhibitor.2018
- Author(s)
  Kunimasa K, Nakamura H, Sakai K, Kimura M, Inoue T, Tamiya M, Nishino K, Kumagai T, Nakatsuka S, Endo H, Inoue M, Nishio K, Imamura F.
- Journal Title
  
  Ann Oncol
  
  Volume: 29(10) Issue: 10 Pages: 2145-2147
- DOI
  10.1093/annonc/mdy312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Mutational activation of the epidermal growth factor receptor down-regulates major histocompatibility complex class I expression via the extracellular signal-regulated kinase in non-small cell lung cancer.2018
- Author(s)
  Watanabe S, Hayashi H, Haratani K, Shimizu S, Tanizaki J, Sakai K, Kawakami H, Yonesaka K, Tsurutani J, Togashi Y, Nishio K, Ito A, Nakagawa K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 110(1) Issue: 1 Pages: 52-60
- DOI
  10.1111/cas.13860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17K18388
[Journal Article] Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach: a multi-institutional research study.2018
- Author(s)
  Vaughn CP, Costa JL, Feilotter HE, Petraroli R, Bagai V, Rachiglio AM, Marino FZ, Tops B, Kurth HM, Sakai K, Mafficini A, Bastien RRL, Reiman A, Le Corre D, Boag A, Crocker S, Bihl M, Hirschmann A, Scarpa A, Machado JC, Blons H, Sheils O, Bramlett K, Ligtenberg MJL, Cree IA, Normanno N, Nishio K, Laurent-Puig P
- Journal Title
  
  BMC cancer
  
  Volume: 18(1) Issue: 1 Pages: 828-828
- DOI
  10.1186/s12885-018-4736-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Exploration of resistance mechanisms for epidermal growth factor receptor-tyrosine kinase inhibitors based on plasma analysis by digital polymerase chain reaction and next-generation sequencing.2018
- Author(s)
  Iwama E, Sakai K, Azuma K, Harada D, Nosaki K, Hotta K, Nishio M, Kurata T, Fukuhara T, Akamatsu H, Goto K, Shimose T, Kishimoto J, Nakanishi Y, Nishio K, Okamoto I.
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Issue: 12 Pages: 3921-3933
- DOI
  10.1111/cas.13820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07271, KAKENHI-PROJECT-18K15214, KAKENHI-PLANNED-17H06404
[Journal Article] Serpina3n, dominantly expressed in female osteoblasts, suppresses the phenotypes of differentiated osteoblasts in mice.2018
- Author(s)
  Ishida M, Kawao N, Okada K, Tatsumi K, Sakai K, Nishio K, Kaji H.
- Journal Title
  
  Endocrinology
  
  Volume: 159 Pages: 3775-3790
- DOI
  10.1210/en.2018-00639
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06863, KAKENHI-PLANNED-15H05940, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-16K08534, KAKENHI-PROJECT-17K18256, KAKENHI-ORGANIZER-15H05935
[Journal Article] A comprehensive gene mutation analysis of liquid biopsy samples from patients with metastatic colorectal cancer to the ovary: A case report2018
- Author(s)
  Iwahashi N, Sakai K, Noguchi T, Yahata T, Toujima S, Nishio K, Ino K
- Journal Title
  
  Oncol Lett
  
  Volume: 16 Pages: 6431-6436
- DOI
  10.3892/ol.2018.9467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11293, KAKENHI-PROJECT-18K16776, KAKENHI-PLANNED-17H06404
[Journal Article] HER2 genomic amplification in circulating tumor DNA and estrogen receptor positivity predict primary resistance to trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer.2018
- Author(s)
  Sakai H, Tsurutani J, Iwasa T, Komoike Y, Sakai K, Nishio K, Nakagawa K.
- Journal Title
  
  Breast Cancer
  
  Volume: 25(5) Issue: 5 Pages: 605-613
- DOI
  10.1007/s12282-018-0861-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-26430174
[Journal Article] A case of ALK-rearranged non-small cell lung cancer that responded to ceritinib after development of resistance to alectinib.2018
- Author(s)
  Makuuchi Y, Hayashi H, Haratani K, Tanizaki J, Tanaka K, Takeda M, Sakai K, Shimizu S, Ito A, Nishio K, Nakagawa K.
- Journal Title
  
  Oncotarget
  
  Volume: 9(33) Issue: 33 Pages: 23315-23319
- DOI
  10.18632/oncotarget.25143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Clinical characteristics of non-small cell lung cancer harboring mutations in exon 20 of EGFR or HER2.2018
- Author(s)
  Takeda M, Sakai K, Hayashi H, Tanaka K, Tanizaki J, Takahama T, Haratani K, Nishio K, Nakagawa K.
- Journal Title
  
  Oncotarget
  
  Volume: 9(30) Issue: 30 Pages: 21132-21140
- DOI
  10.18632/oncotarget.24958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Genital mucosal melanoma with somatic SF3B1 R625C mutation.2018
- Author(s)
  Oiso N, Sakai K, Yanagihara S, Nishio K, Kawada A.
- Journal Title
  
  Eur J Dermatol
  
  Volume: 28(3) Issue: 3 Pages: 414-415
- DOI
  10.1684/ejd.2018.3281
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06404
[Journal Article] Clinical significance of Akt2 in advanced pancreatic cancer treated with erlotinib.2017
- Author(s)
  Banno E, Togashi Y, de Velasco MA, Mizukami T, Nakamura Y, Terashima M, Sakai K, Fujita Y, Kamata K, Kitano M, Kudo M, Nishio K
- Journal Title
  
  Int J Oncol
  
  Volume: 50 Issue: 6 Pages: 2049-2058
- DOI
  10.3892/ijo.2017.3961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09410, KAKENHI-PROJECT-17K18388, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17J09900
[Journal Article] Tumor Immune Microenvironment and Nivolumab Efficacy in EGFR Mutation-Positive Non-Small Cell Lung Cancer Based on T790M Status After Disease Progression During EGFR-TKI Treatment2017
- Author(s)
  K. Haratani, H. Hayashi*, T. Tanaka, H. Kaneda, Y. Togashi, K. Sakai, K. Hayashi, S. Tomida, Y. Chiba, K. Yonesaka, Y. Nonagase, T. Takahama, J. Tanizaki, K. Tanaka, T. Yoshida, K. Tanimura, M. Takeda, H. Yoshioka, T. Ishida, T. Mitsudomi, K. Nishio and K. Nakagawa
- Journal Title
  
  Annals of Oncology
  
  Volume: in press Issue: 7 Pages: 1532-1539
- DOI
  10.1093/annonc/mdx183
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K21506, KAKENHI-PROJECT-17K18388, KAKENHI-PUBLICLY-16H01574, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-17J09900
[Journal Article] Clonal composition of human ovarian cancer based on copy number analysis reveals a reciprocal relation with oncogenic mutation status.2017
- Author(s)
  Sakai K, Ukita M, Schmidt J, Wu L, De Velasco MA, Roter A, Jevons L, Nishio K, Mandai M.
- Journal Title
  
  Cancer Lett
  
  Volume: 1;405 Pages: 22-28
- DOI
  10.1016/j.canlet.2017.07.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-16H05477
[Journal Article] Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study).2017
- Author(s)
  Matsuoka H, Tsurutani J, Chiba Y, Fujita Y, Terashima M, Yoshida T, Sakai K, Otake Y, Koyama A, Nishio K, Nakagawa K
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Issue: 1 Pages: 674-674
- DOI
  10.1186/s12885-017-3664-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07204, KAKENHI-PLANNED-17H06404
[Journal Article] Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing.2015
- Author(s)
  Sakai K, Tsurutani J, Yamanaka T, Yoneshige A, Ito A, Togashi Y, De Velasco MA, Terashima M, Fujita Y, Tomida S, Tamura T, Nakagawa K, Nishio K.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: e0121891-e0121891
- DOI
  10.1371/journal.pone.0121891
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26830098
[Journal Article] Multiplex genomic profiling of non–small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study2014
- Author(s)
  Okamoto I, Sakai K, Morita S, Yoshioka H, Kaneda H, Takeda K, Hirashima T, Kogure Y, Kimura T, Takahashi T, Atagi S, Seto T, Sawa T, Yamamoto M, Satouchi M, Okuno M, Nagase S, Takayama K, Tomii K, Maeda T, Oizumi S, Fujii S, Akashi Y, Nishino K, Ebi N, Nakagawa K, Nakanishi Y, Nishio K.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 2293-2304
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Detection of EGFR T790M mutation in plasma DNA from patients2013
- Author(s)
  Sakai, K., Horiike, A., Darryl, I., Keita, K., Fujita, Y., Tanimoto, A., Sakatani, T., Saito, R., Kaburaki, K., Noriko, Y., Ohyanagi, F., Nishio, M., Nishio, K.
- Journal Title
  
  Cancer Sci
  
  Volume: 104(9) Pages: 1198-204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701013
[Journal Article] Detection of EGFR T790M mutation in plasma DNA from patients refractory to EGFR tyrosine kinase inhibitor.2013
- Author(s)
  Sakai, K., Horiike, A., Darryl, I., Keita, K., Fujita, Y., Tanimoto, A., Sakatani, T., Saito, R., Kaburaki, K., Noriko, Y., Ohyanagi, F., Nishio, M., Nishio, K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104(9) Issue: 9 Pages: 1198-204
- DOI
  10.1111/cas.12211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24240122, KAKENHI-PROJECT-24701013, KAKENHI-PROJECT-25350979
[Journal Article] A novel mass spectrometry–based assay for diagnosis of EML4-ALK–positive non–small cell lung cancer.2012
- Author(s)
  Sakai K, Okamoto I, Takezawa K, Hirashima T, Kaneda H, Takeda M, Matsumoto K, Kimura H, Fujita Y, Nakagawa K, Arao T, Nishio K.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 7 Pages: 913-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] A novel mass spectrometry-based assay for diagnosis of EML4-ALK-positive non-small cell lung cancer2012
- Author(s)
  Sakai K. et al
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7 Issue: 5 Pages: 913-8
- DOI
  10.1097/jto.0b013e31824c7f7a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701013
[Journal Article] Clinical Outcome of Thoracic Radiotherapy for Locally Advanced NSCLC with EGFR Mutations or EML4-ALK.2012
- Author(s)
  Hayashi H, Okamoto I, Kimura H, Sakai K, Nishimura Y, Nishio K, Nakagawa K.
- Journal Title
  
  Anticancer Research
  
  Volume: 32(10) Pages: 4533-4537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] A novel mass spectrometry-based assay for EML4 exon 13 ALK exon 20 EML4 exon 6 ALK exon 20 diagnosis of EML4-ALK-positive non-small cell lung cancer2012
- Author(s)
  Sakai, K., Okamoto, I., Takezawa, K., Hirashima, T., Kaneda, H., Takeda, M., Matsumoto, K., Kimura, H., Fujita, Y., Nakagawa, K., Arao, T., Nishio, K.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7(5) Pages: 913-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701013
[Journal Article] Clinical outcome for EML4-ALK–positive patients with advanced non–small cell lung cancer treated with first-line platinum-based chemotherapy.2012
- Author(s)
  Takeda M, Okamoto I, Sakai K, Kawakami K, Nishio K, Nakagawa K.
- Journal Title
  
  Annals of Oncology
  
  Volume: 23(11) Pages: 2931-2936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Marked response to both S-1 and pemetrexed in a patient with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinoma.2012
- Author(s)
  Kaneda H, Okamoto I, Sakai K, Tanizaki J, Takeda M, Nishio K, Nakagawa K.
- Journal Title
  
  Acta Oncologica
  
  Volume: 51(7) Pages: 942-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Journal Article] Clinical outcome for EML4-ALK-positive patients with advanced non-small-cell lung cancer treated with first-line platinum-based chemotherapy2012
- Author(s)
  Takeda, M., Okamoto, I., Sakai, K., Kawakami, H., Nishio, K., Nakagawa, K.
- Journal Title
  
  Ann Oncol
  
  Volume: 23(11) Pages: 2931-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701013
[Journal Article] Activation of HER family signaling as a mechanism of acquired resistance to ALK inhibitors in EML4-ALK-positive non-small cell lung cancer.2012
- Author(s)
  Tanizaki J, Okamoto I, Okabe T, Sakai K, Tanaka K, Hayashi H, Kaneda H, Takezawa K, Kuwata K, Yamaguchi H, Hatashita E, Nishio K, Nakagawa K.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 18(22) Pages: 6219-6226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501359
[Presentation] 原発不明がん患者を対象としたニボルマブの有効性に関する第II相試験（NivoCUP）のフォローアップ解析2023
- Author(s)
  船越洋平、谷崎潤子、米盛勧、秋吉宏平、上田弘樹、滝口裕一、三浦裕司、畝川芳彦、小峰啓吾、沖川佳子、木寺康裕、福岡和也、伊藤彰彦、千葉康敬、坂井和子、南博信、西尾和人、中川和彦、林秀敏
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27468
[Presentation] リキッドバイオプシ―によるMRD解析に用いられ得る技術2023
- Author(s)
  西尾和人、坂井和子
- Organizer
  第64回日本肺癌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27468
[Presentation] がん遺伝子検査の進歩2023
- Author(s)
  西尾和人、坂井和子
- Organizer
  第64回日本臨床検査医学会近畿支部総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27468
[Presentation] リキッドバイオプシーの新展開2021
- Author(s)
  坂井和子
- Organizer
  第6回Liquid Biopsy研究会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] Clinical Application of the FoundationOne Assay to Therapeutic Decision-Making for Patients with Advanced Solid Tumors2021
- Author(s)
  Takeda Masayuki, Takahama Takayuki, Sakai Kazuko, Shimizu Shigeki, Watanabe Satomi, Kawakami Hisato, Tanaka Kaoru, Fukuoka Kazuya, Nakagawa Kazuhiko, Nishio Kazuto
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07721
[Presentation] ten欠損前立腺癌におけるJAK1/2標的治療が糞便中のマイクロバイオームに与える影響について2020
- Author(s)
  デベラスコ・マルコ, 倉由吏恵, 坂井和子, 野澤昌弘, 吉川和宏, 西尾和人, 植村天受
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 大腸炎誘発大腸癌と微生物叢の多様性のインタラクトーム解析2020
- Author(s)
  西尾和人, 坂井和子, 倉由吏恵, 竹ヶ原京志郎, デベラスコ・マルコ
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 前立腺癌特異的Ptenノックアウトマウスにおけるマイクロバイオームについての検討2020
- Author(s)
  倉由吏恵, 坂井和子, 藤田至彦, 野澤昌弘, 吉川和宏, 西尾和人, デベラスコ・マルコ, 植村天受
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 腫瘍免疫環境プロファイルと抗腫瘍免疫反応2019
- Author(s)
  デベラスコマルコ　倉由吏恵　森康範　清水信貴　大關孝之　坂井和子　野澤昌弘　吉村一宏　吉川和宏　西尾和人　植村天受
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 潰瘍性大腸炎関連大腸癌の予防における内視鏡的粘膜下層剥離術の役割2019
- Author(s)
  櫻井俊治　坂井和子　永井知行　樫田博史　筑後孝章　根津理一郎　西尾和人　工藤正俊
- Organizer
  第78回日本癌学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 炎症に起因する病態における宿主とその微小環境との相互作用は生体リガンドを介した化学コミュニケーションとして作用する2019
- Author(s)
  坂井和子　櫻井俊治　上嶋一臣　角田郁生　尾村誠一　高濱隆幸　西尾和人
- Organizer
  新学術領域研究【化学コミュニ】第5回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] 宿主と環境の遺伝子解析に基づくがん分子標的探索2019
- Author(s)
  坂井和子　西尾和人
- Organizer
  第23回日本がん分子標的治療学会　学術集会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] Impact of Co-Mutations in EGFR-Mutated NSCLC Before EGFR-TKIs on T790M Mutation Status After TKIs2019
- Author(s)
  武田真幸,坂井和子,林秀敏,田中薫,原谷浩司,高濱隆幸,加藤了資,米阪仁雄,西尾和人,中川和彦
- Organizer
  日本肺癌学会
- Data Source
  KAKENHI-PROJECT-19K07721
[Presentation] Clonality and loss of heterogeneity are associated with prognosis amd subtypes in high grade serous ovarian cancer.2018
- Author(s)
  Hisamitsu Takaya, Hidekatsu Nakai, Kazuko Sakai, Kazuto Nishio, Noriomi Matsumura
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02947
[Presentation] Clinical sequencing of circulating tumor DNA by CAPP-seq2018
- Author(s)
  坂井和子
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07150
[Presentation] A new strategy to personalize surveillance program for colitis-associated cancer2017
- Author(s)
  Toshiharu Sakurai, Kazuko Sakai, Hiroshi Kashida, Kazuto Nishio, Masatoshi Kudo
- Organizer
  第25回　日本消化器関連学会 (International Session, Symposium)
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] PTENノックアウト前立腺癌マウスモデルにおける腫瘍免疫の包括的分析2017
- Author(s)
  De Velasco Marco A., 倉由吏恵, 坂井和子, 杉本公一, 野澤昌弘, 吉村一宏, 吉川和宏, 西尾和人, 植村天受
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] まれなEGFR遺伝子変異L861QおよびS768I陽性非小細胞性肺癌に対する最適なEGFR阻害剤の選択2017
- Author(s)
  坂野恵里, 冨樫庸介, 中村雄, 千葉眞人, 小林祥久, 林秀敏, 谷崎潤子, 寺嶋雅人, デ・ベラスコ・マルコ A., 坂井和子, 藤田至彦, 光冨徹哉, 西尾和人
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06404
[Presentation] Detection of EGFR T790M mutation in plasma DNA from patients refractory to EGFR tyrosine kinase inhibitor2013
- Author(s)
  Sakai, K., Horiike, A., Darryl, I., Keita, K., Fujita, Y., Tanimoto, A., Sakatani, T., Saito, R., Kaburaki, K., Noriko, Y., Ohyanagi, F., Nishio, M., Nishio, K.
- Organizer
  The 11th Annual Meeting of Japanese Society of Medical Oncology
- Place of Presentation
  Sendai, JAPAN
- Data Source
  KAKENHI-PROJECT-24701013
[Presentation] Detection of EGFR T790M mutation in plasma DNA from patients refractory to EGFR tyrosine kinase inhibitor.2013
- Author(s)
  Sakai, K., Horiike, A., Darryl, I., Keita, K., Fujita, Y., Tanimoto, A., Sakatani, T., Saito, R., Kaburaki, K., Noriko, Y., Ohyanagi, F., Nishio, M., Nishio, K.
- Organizer
  The 11th Annual Meeting of Japanese Society of Medical Oncology
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24701013
[Presentation] A novel mass spectrometry-based assay for diagnosis of EML4-ALK-positive non-small cell lung cancer2012
- Author(s)
  Sakai, K., Okamoto, I., Takezawa, K., Hirashima, T., Kaneda, H., Takeda, M., Matsumoto, K., Kimura, H., Fujita, Y., Nakagawa, K., Arao, T., Nishio, K.
- Organizer
  The 10th Annual Meeting of Japanese Society of Medical Oncology
- Place of Presentation
  Osaka, JAPAN
- Data Source
  KAKENHI-PROJECT-24701013
[Presentation] Detection of EML4-ALK in serum RNA from lung cancer patients using MassARRAY platform2012
- Author(s)
  Kudo, K., Nishio, M., Sakai, K., Tanimoto, A., Sakatani, T., Saito, R., Kaburaki, K., Yanagitani, N., Horiike, A., Ohyanagi, F., Nishio, K.
- Organizer
  ASCO annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24701013
[Presentation] MassARRAYによるEML4-ALK検出系の構築2012
- Author(s)
  坂井和子、岡本勇、竹澤健、平島智徳、金田裕靖、武田真幸、松本和子、木村英晴、藤田至彦、中川和彦、荒尾徳三、西尾和人
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24501359
[Presentation] Clinical outcome for EML4-ALK-positive patients with advanced non-small cell lung cancer treated with first-line platinumbased　chemotherapy.2012
- Author(s)
  Masayuki Takeda, Isamu Okamoto, Kazuko Sakai, Hisato Kawakami, Kazuto Nishio, Kazuhiko Nakagawa.
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24501359
[Presentation] Multiplex genomic profiling of non-small cell lung cancer patients enrolled in the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin (WJOG6611LTR)
- Author(s)
  H Yoshioka, I Okamoto, K Sakai, S Morita, H Kaneda, K Takeda, T Hirashima, Y Kogure, T Kimura, T Takahashi, S Atagi, T Seto, T Sawa, M Yamamoto, M Satouchi, M Okuno, S Nagase, K Nakagawa, Y Nakanishi, K Nishio
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago
- Year and Date
  2014-05-30 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-24501359
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Sakai Kazuko 坂井 和子

SAKAI Kazuko 坂井 和子

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Evaluation of minimal residual disease in postoperative lung cancer using platelet RNA influenced by the tumor environment.Principal Investigator

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Investigation of molecular pathology based on quantitative evaluation of intratumor heterogeneity in hepatocellular carcinomaPrincipal Investigator

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Detection of ALK fusion genes in plasma exosomesPrincipal Investigator

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Sakai Kazuko 坂井和子

SAKAI Kazuko 坂井和子

[Book] 日本臨牀 75巻増刊号8号　がん転移学 (上)がん転移のメカニズムと治療戦略 : その基礎と臨床 - 序文 : 転移がん治療の進歩と課題「転移の分子診断」2017