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UNEMOTO tsutomu  畝本 力

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UNEMOTO Tsutomu  畝本 力

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Researcher Number 30089601
External Links
Affiliation (based on the past Project Information) *help 1997 – 1999: 千葉大学, 薬学部, 教授
1987 – 1995: 千葉大学, 薬学部, 教授
1986 – 1987: 千葉大学, 生物活性研究所, 教授
1986: Res. Inst. for Chemobiodynamics, Chiba Univ., Professor, 生物活性研究所, 教授
Review Section/Research Field
Principal Investigator
Biological pharmacy
Except Principal Investigator
細菌学 / 海洋生物学
Keywords
Principal Investigator
NADH-quinone reductase / Respiratory chain / Vibrio alginolyticus / Marine bacteria / 海洋細菌 / 呼吸鎖 / DT-diaphorase / FMN / FAD / Marine bacterium … More / nqr gene / Sodium ion pump / NADPH-quinone reductase / Quinone metabolism / Quinone toxicity / Induction / 大腸菌 / キノン代謝 / キノン毒性 / 誘導 / NADHーguinone reductase / メナジオン / Flavoprotein / <Na^+> Pump / サブユニット構造 / NADH-quihohe reductase / フラビン蛋白 / 【Na^+】ポンプ / over expression / marine bacteria / Vivric alginalyticus / Na^+ pump / vespiratery chain / Na^+-translocating / コロルミシン / ナトリウム輸送 / NADH-キノンリダクターゼ / Na^+ポンプ / nqp gene / Cloning of NQR gene / Sidium pump / Sodium ion transport / 遺伝子解析 / 電子伝達系 / NADH-キノン・リダクターゼ / ナトリウムポンプ / ナトリウムイオン輸送 / Escherichia coli / 2-Methylene-4-butyrolactone / キノン化合物 / 誘導基質 / 2-メチレン-4-ブチロラクトン / Oxygen stress / E. coli / DT-Diaphorase / Menadione / 二電子還元 / 一電子還元 / 活性酵素 / キノン / 毒性 / 酸素ストレス / DTーdiaphorase … More
Except Principal Investigator
Staphylococcal alpha-toxin / ホスホリパーゼC / ロイコシジンS及びF成分 / α毒素 / 黄色ブドウ球菌 / Vibrio alginolyticus / 呼吸鎖 / 海洋細菌 / HL-60 cells / GTP-binding protein / Phospholipase C / Phospholipase A_2 / ADP-ribosyltransferase / Leukocidin S and F comp. / NAD / ホスファチジルイノシトール / ホスファチジルコリン / ホスホリバーゼA_2 / ロイコシジンF成分 / ロイコシジンS成分 / ブドウ球菌α毒素 / ヒト前骨髄性白血病HL-60細胞 / GTP結合蛋白質 / ADPリボシル転移酵素 / ホスホリパ-ゼC / ホスホリパ-ゼA_2 / cyclic AMP / phosphatidylserine / calmodulin / phosphorylation / potassium ion channel / human promyelocytic leukemia cell (HL-60) / phospholipase A_2 / leukocidin S and F components / 【K^+】チャンネル / 【Ca^(2+)】チャンネル / ホスホリパーゼ【A_2】 / メチルトランスフェラーゼ / ブドウ球菌 / K^+イオンチャンネル / Ca2+-カルモジュリン依存プロテインキナーゼ / アラキドン酸カスケード / ホスホリパーゼA_2 / Marine bacterium / Sodium transport / Respiratory chain / Moderate halophile / NQR operon / NADH-quinone reductase / Sodium pump / 遺伝子解析 / ナトリウムイオン輸送 / 中度好塩細菌 / NQRオペロン / NADH-キノン・リダクターゼ / ナトリウムポンプ / pharmacy education / drug safety / mechanism of drug action / evaluation / pharmaceutical / synthetic drug / natural resources / new drug development / 安全性 / 体内動態 / 薬理学的研究 / 天然薬用資源 / 薬学教育 / 薬物の安全性 / 薬効発現機構 / 薬効評価 / 合成医薬品 / 天然資源 / 新薬開発 / サブユニット構成 / NADH-guinone reductase / FMN / FAD / フラビン蛋白 / Na^+ポンプ Less
  • Research Projects

    (10 results)
  • Co-Researchers

    (46 People)
  •  Structure and function of NaィイD1+ィエD1-pumping NADH-quinone reductasePrincipal Investigator

    • Principal Investigator
      UNEMOTO tsutomu
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  Similarity Analysis of Na^+-Translocating NADH-Quinone Reductase Gene between Moderate Halophiles and Marine Bacteria

    • Principal Investigator
      HAYASHI Maki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      海洋生物学
    • Research Institution
      Chiba University
  •  Cloning and Structural Analysis of Na^+-Translocating NADH-Quinone Reductase of Marine BacteriaPrincipal Investigator

    • Principal Investigator
      UNEMOTO Tsutomu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  Role of Quinone-Metabolizing Enzymes on the Toxicities of Quinone Derivatives.Principal Investigator

    • Principal Investigator
      UNEMOTO Tsutomu
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  General Studies on the Development of Novel Materials and their Evaluation as new Drugs

    • Principal Investigator
      SUZUKI Tokuji
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Induction of an NADH-quinone reductase which alleviate menadione toxicity in Escherichia coli.Principal Investigator

    • Principal Investigator
      UNEMOTO Tsutomu
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Chiba University
  •  Studies on the analysis of molecular structure and signal-transduction mechanism of the cell-membrane damaging by staphylococcal cytolytic toxins.

    • Principal Investigator
      KATO Iwao
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      Chiba University
  •  海洋細菌のNa^+輸送NADH-キノン・リダクターゼのサブユニット構成とその機能

    • Principal Investigator
      HAYASHI Maki
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Chiba University
  •  The molecular structure of staphylococcal alpha-toxin and leukocidin and their damaging action on the target cell membranes

    • Principal Investigator
      KATO IWAO Professor
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      School of Medicine, Chiba University
  •  Purification and Reconstitution of the Coupling Site of <Na^+> Transport in the Respiratory Chain of a Marine Bacterium.Principal Investigator

    • Principal Investigator
      UNEMOTO Tsutomu
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Research Institute for Chemobiodynamics, Chiba University
  • 1.  HAYASHI Maki (50092086)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  JAMARI F.
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KNAUS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  FRIESEN
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NOUJAIM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  LOCOCK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  TAM
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  PASUTTO
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  BIGGS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  MICETICH
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  WIEBE
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  WOLOWYK
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  KATO IWAO Professor (40012702)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  MORINAGA NAOKO (20092108)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  COUTTS
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  MOSKALYK
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  SUZUKI Tokuji (40010219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SATO Testuo (60092061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HIROSE Seiyu (40009163)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  IMANARI Toshio (20012619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SAWAI Testuo (70009174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  IGARASHI Kazuei (60089597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  WATANABE Kazuo (80019124)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ISHII Hisashi (70009166)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HINO Toru (10009160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SAKAI Shin-ichiro (20009161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  YAMAZAKI Mikio (70089598)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  MURAKOSHI Isamu (30009162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KAMIO Yoshiyuki (00109175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  NODA Masatoshi (60164703)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  山根 靖弘 (40009155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  仲井 由宣 (80009159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  細谷 東一郎 (10019648)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  BIGGS D. F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  KNAUS E. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  LOCOCK R. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  PASUTTO F. M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  FRIESEN A. J. D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  COUTTS R. T.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  TAM Y. K.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  NOUJAIM A. A.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  WOLOWYK M. W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  MICETICH R. G.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  MOSKALYK R. E.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  WIEBE L. I.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  COUTIS
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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