Tanaka Yoshiya 田中良哉

… Alternative Names

TANAKA Yoshiya 田中良哉

田中義哉タナカヨシヤ

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Researcher Number	30248562
Other IDs	https://orcid.org/0000-0002-0807-7139
External Links
Affiliation (Current)	2025: 産業医科大学, 医学部, 特別教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 産業医科大学, 医学部, 教授 2000 – 2013: University of Occupational and Environmental Health, School of Medicine, Professor, 医学部, 教授 1996 – 1999: University of Occupational and Environmental Health Medicine, Assist. Professor, 医学部, 講師 1998: 産業医科大学, 医学部講師, 講師 1993 – 1997: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 内科学一般 / General internal medicine (including Psychosomatic medicine) Except Principal Investigator 膠原病・アレルギー・感染症内科学 / Basic Section 54020:Connective tissue disease and allergy-related / 内分泌・代謝学 / 内科学一般 / Endocrinology / Gastroenterology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Basic Section 52010:General internal medicine-related … More / Collagenous pathology/Allergology / Medical sociology / Hematology / Pathological medical chemistry / Immunology / Orthopaedic surgery / Endocrinology / Biological Sciences Less
Keywords	Principal Investigator インテグリン / 血管内皮細胞 / T細胞 / adhesion molecules / サイトカイン / 接着分子 / CD44 / プロテオグリカン / 慢性関節リウマチ / ICAM-1 … More / integrin / 滑膜細胞 / IL-1 / ホメオサーベイランス / 酸化ストレス / アポトーシス / 免疫系 / ストレス科学 / ケモカイン / organ-tropism / homing molecules / co-stimulatory molecules / endothelial cells / T cells / systemic lupus erythematosus / リンパ球 / 全身エリテマトーデス / 共刺激分子 / 臓器特異的浸潤 / 帰巣分子 / 細胞表面抗原 / 全身性エリテマトーデス / apoptosis / cell cycle / hyaluronan / synovial cells / Rheumatoid arthritis / 細胞増殖 / 細胞死 / Fas / 細胞周期 / ヒアルロン酸 / Metastasis / Endothelium / Adhesion / Integrin / Proteoglycan / Chemokine / Leukemia / 転移 / 細胞接着 / chemokine / 白血病 / MIP-1beta / proteoglycan / endothelium / T lymphocyte / rheumatoid arthritis / MIP-1β / Tリンパ球 / ストレス / 代謝系 / 神経伝達物質 / 免疫伝達物質 / 神経伝達物資 / 生存脳 / ランゲルハンス細胞 / 神経ペプチド / 樹状細胞 / デンドライト / 炎症 / ヘパラン硫酸 … More Except Principal Investigator 骨芽細胞 / RANKL / 関節リウマチ / 破骨細胞 / LFA-1 / 接着分子 / ICAM-1 / M-CSF / 細胞接着 / ATL / adhesion molecule / 骨粗鬆症 / B細胞 / リンパ球 / PTH / 骨吸収 / サイトカイン / 遺伝子導入 / ChIP / スーパーエンハンサー / 免疫代謝 / SLE / FOXP-3 / CD25 / CD4 / FGF-2 / 血管内皮細胞 / cyclooxygenase-2 / HTLV-I / Tax / rheumatoid arthritis / c-Myc / H-Ras / OCIF / IL-1α / cell adhesion / lymphocytes / p53 / bone resorption / osteoblast / Osteoblast / Osteoclast / 副甲状腺ホルモン / hemophilia / HIV / hepatocyte growth factor / HGF / Con-A / 骨代謝 / 膠原病 / 自己免疫疾患 / 樹状細胞 / ヒアルロン酸 / CD44 / エピジェネティック / 線維化進行性間質性肺疾患 / 全身性強皮症 / バイオインフォマティクス / 次世代シークエンス / 疾患ゲノム解析 / 免疫アレルギー疾患 / シングルセル解析 / オミクス解析 / シングルセルシークエンス / 遺伝統計学 / 統合シークエンス解析 / モノアミン / HVA / SDF-1α / SCGF-1β / NPSLE / CD20陽性B細胞 / plasmocyte / P2RY10 / ＣD20陽性B細胞 / 間質性肺炎 / 膠原病関連間質性肺炎 / 画像解析 / 膠原病に伴う間質性肺疾患 / 関節リウマチに伴う間質性肺疾患 / 亜型解析 / 遺伝学的解析 / 疾患レジストリ / 難病プラットフォーム / 疾患活動性指標 / GWAS / クラスター解析 / ゲノム解析 / レジストリ / 予後不良病型 / 疾患活動性 / レジストリ研究 / ベーチェット病 / ドパミン受容体シグナル / 関節破壊 / 炎症 / MED1 / SNP / ubash3a / eRNA / BACH2 / UBASH3A / CD4陽性T細胞 / 免疫細胞代謝 / 全身性エリテマトーデス / 必須アミノ酸 / mTORC1 / RA / mTOR / 免疫学 / 骨破壊 / 14-3-3 eta / PADI4 / 関節液 / ネクロプトーシス / TNF-α / シトルリン化 / PAD4 / 14-3-3η / マクロファージ / メトトレキサート / 構造的寛解 / 休薬 / TNF阻害薬 / 職業的寛解 / 機能的寛解 / 臨床的寛解 / 寛解 / メソトレキサート / Lymphocytes / P-glycoprotein / drug resistance / 遺伝子発現調節 / P-糖蛋白質 / 多剤耐性遺伝子 / RA synovial endothelial cells / ヘパラン硫酸 / RA滑膜線維芽細胞 / autoimmune / regulatory T lymphocyte / FOX-3 / 自己免疫 / 制御性Tリンパ球 / Gene chip / endothelial cells / osteoclasts / osteoblasts / β_1インテグリン / ヘパラン硫酸プロテオグリカン / Gene Chip / bone metabolism / adult T-cell leukemia / 成人T細胞性白血病 / リポポリサッカライド / 成人T細胞白血病 / HTLV-1 / angiostatin / monoclonal antibody / gene therapy / 血管新生抑制因子 / 慢性関節リウマチ / anti-oncogene / gene expression / Integrins / proto-oncogenes / 癌抑制遺伝子 / 遺伝子発現 / インテグリン / プロトオンコジーン / 1.25(OH)ィイD22ィエD2DィイD23ィエD2 / 1.25(OH)_3D_3 / 1.25(OH)_2D_3 / protooncogene products / adaptors / protein tyrosine phosphatases / protein tyrosine kinase / signal transduction / T細胞受容体 / 子宮外発生法 / チロシンリン酸化 / プロトオンコジーン産物 / アダプター / チロシンホスファターゼ / チロシンキナーゼ / シグナル伝達 / TAX protein / IL-1 gene / Cell Adhesion Molecules / Hypercalcemia / 核内転写因子 / IL-1β遺伝子 / Tax蛋白 / G蛋白 / イソテグン / TAX蛋白 / TAX蛋白質 / IL-1遺伝子 / 細胞接着分子 / 高Ca血症 / MHC-class-II antigen / cytotoxic T cell / post-transcriptional regulation / transfection / thyroid carcinoma / Class II主要組織適合抗原 / ClassII主要組織適合抗原 / 細胞傷害性T細胞 / 転写後調節 / 甲状腺癌 / chondrocyte / hyaluronic acid / osteoclast / 細胞外基質 / 軟骨細胞 / ICAM-1軟骨細胞) / hepatic necrosis / transforming growth factor / liver fibrosis / liver regeneration / extracellular matrix / TGFβ / 肝再生 / 肝線維症 / 肝線維化 / 生体内情報伝達 / TGFβ_1 / 細胞外マトリックス / 肝再生抑制 / Estrogen / Bone formation rate / Trabecular bone / Ovariectomized rats / Interleukin-6 / Anti GP130 antibody / 骨髄細胞の分化 / カップリング異常 / 挫骨神経切除マウス / アジュバント関節炎ラット / 骨計測 / CFU-GM / CFU-f / 骨髄細胞 / 骨不動化 / 骨芽細胞と破骨細胞 / 坐骨神経切除マウス / エストロゲン / 骨形成率 / 海綿骨 / 卵巣摘出ラット / インターロイキン6 / GP130抗体 / tissue infiltration / 臓器浸潤 / AIDS / 血友病 / 臓器侵潤 / interleukin-8 / platelet / endothelial injury / neutrophil / ischemia-reperfusion injury / liver transplant / IL-8 / 血小板 / 内皮細胞障害 / 好中球 / 虚血再灌流障害 / 肝移植 / Isoelectric point / Hydroxyl radical / Cytokine / Iron / Ferritin / クロマトフォーカシング / IFN-γ / IL-6 / 成人スチル病 / 等電点 / 活性酸素 / 鉄 / フェリチン / Wnt10 / リモデリング抑制 / 滑膜細胞 / 単球系細胞 / 共刺激分子 / Jak阻害剤 / Jak3 / 滑膜線維芽細胞 / リウマチ学 / 自己抗体 / 転写因子 / 抗転写因子抗体 / 膠原病学 / lipid raft / ガレクチン9 / 選択的エストロゲン受容体モジュレーター / 骨質 / 閉経後骨粗鬆症 / 糖尿病 / 骨吸収マーカー / メトホルミン / ピオグリタゾン / ホモシステイン / 2型糖尿病 / 骨折 / 内分泌学 / Stat5 / 単球 / Stat6 / 臨床免疫学 / Tacrolimus(FK506) / 筋膜炎 / TNFR1 / TNFα / 周期熱 / TRAPS / アデノウイルス / MMP / 浸潤 / 転移 / TGF-β / 1α,25(OH)_2VD_3 Less

全身性強皮症に伴う線維化進行性間質性肺疾患のエピジェネティクス異常機構の解明
- Principal Investigator
  
  福與俊介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
B細胞のスーパーエンハンサー異常を介した関節リウマチの新規病態形成基盤の解明
- Principal Investigator
  
  山形薫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
神経精神ループスにおける生理活性物質不均衡、B細胞分化異常を介した病態機構の解明
- Principal Investigator
  
  岩田慈
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Wakayama Medical University
Elucidation of immune and allergic disease dynamics by integrative sequencing analysis
- Principal Investigator
  
  岡田随象
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  The University of Tokyo
疾患進行を示す膠原病関連間質性肺疾患の画像解析：胸部CTの新たな診断基準の策定
- Principal Investigator
  
  川口貴子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Mechanism of human B cell differentiation via amino-acid metabolism -Development of novel therapy for systemic lupus erythematosus-
- Principal Investigator
  
  Iwata Shigeru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
A novel pathogenesis of rheumatoid arthritis due to dysregulated super-enhancer in CD4-positive T cells
- Principal Investigator
  
  YAMAGATA KAORU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Elucidation of pathophysiology and development of new treatments with the neurotransmitter dopamine for rheumatoid arthritis
- Principal Investigator
  
  HANAMI KENTARO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Generation of evidence through registry construction by genome-wide subtype analysis of Behcet's disease
- Principal Investigator
  
  KIRINO Yohei
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Yokohama City University
Critical role of 14-3-3 eta in pathogenesis of rheumatoid arthritis
- Principal Investigator
  
  YAMAGATA KAORU
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  University of Occupational and Environmental Health, Japan
Establishment of the treatment algorithm of the rheumatoid arthritis aimed at clinical, functional and occupational remission.
- Principal Investigator
  
  NAWATA Masao
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical sociology
- Research Institution
  University of Occupational and Environmental Health, Japan
Involvement of Epithelial and endothelial to mesenchymal transition in tissue remolding of rheumatic diseases
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Dynamics of stress-homeosurveillance and its relevance to disease controlPrincipal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Occupational and Environmental Health, Japan
Development of novel medication strategy and drug efficacy on monocyte lineage cells of a JAK3 inhibitor in rheumatoid arthritis patients
- Principal Investigator
  
  YAMAOKA Kunihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic target for aging osteoporosis～New anti-osteoporosis drug with stimulating bone formation～
- Principal Investigator
  
  OKADA Youske
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  University of Occupational and Environmental Health, Japan
A New treatment strategy using analysis of anti-transcriptional factors antibody in connective tissue diseases.
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Function of Stat5 in myeloid lineage cells : A explorative research to control autoimmune disease
- Principal Investigator
  
  YAMAOKA Kunihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Stress-surveillance and signal network originated from dendrite of various cellsPrincipal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic research for osteoporosis with rheumatoid arthritis
- Principal Investigator
  
  OKADA Yosuke
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Treatment strategy for connective tissue diseases using evaluation of P-glycoprotein on lymphocytes
- Principal Investigator
  
  NAKATUSKA Kiesuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
本邦初のTRAPS患者の全国大規模疫学調査と診断基準の作成に関する研究
- Principal Investigator
  
  井田弘明
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Nagasaki University
Analysis of Regulation of FOXP3 expression and induction of regulatory T cells for therapeutic application to autoimmune diseases.
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health
細胞外マトリクス制御分子群を用いた抗浸潤・転移療法の開発
- Principal Investigator
  
  上野光
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Occupational and Environmental Health, Japan
Therapeutic research for osteoporosis with rheumatoid arthritis
- Principal Investigator
  
  OKADA Yosuke
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  University of Occupational and Environmental Health, Japan
Identification of organ-specific cell surface molecules on T cells and endothelial cells in patients with systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health, Japan
Treatment for rheumatoid arthritis with immunogene therapy by angiostatin
- Principal Investigator
  
  SAITO Kazuyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health
Transcriptional activation of the HTLV-I gene in monocytes and macrophages.
- Principal Investigator
  
  TSUKADA Junichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  University of Occupational and Environmental Health, Japan
Role of cyclooxygenase-2 in bone metabolism -analysis of cox-2 konckout mice-
- Principal Investigator
  
  OKADA Yosuke
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  University of Occupational and Environmental Health
破骨細胞分化因子、ODFによる破骨細胞形成に及ぼす接着分子を介した細胞接着の関与
- Principal Investigator
  
  MORIMOTO Isao
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  University of Occupational and Environmental Health, Japan
Establishment of inflammatory and malignant tumor disease model mice based on abnormalities in adhesiveness of immune cells and its clinical application.
- Principal Investigator
  
  MINAMI Yasuhiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
The functional heterogeneity of synovial cells in patients with rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health
Functional analyses of roles of tyrosine kinases/phosphatases in lymhpcyte signaling
- Principal Investigator
  
  MINAMI Yasuhiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Immunology
- Research Institution
  Kobe University
Bone resorbing factor-induced adhesion molecule expression on osteoblast and its-related bone resoption.
- Principal Investigator
  
  MORIMOTO Isao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  University of Occupational and Environmental Health
慢性関節リウマチ滑膜におけるT細胞と血管内皮細胞に特異的に発現する接着分子の同定Principal Investigator
- Principal Investigator
  
  田中良哉
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health, Japan
(Specific Regulation of Mechanism of Hypercalcemia Induction in Adult T Cell Leukemia.)
- Principal Investigator
  
  ETO Sumiya
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  University of Occupational and Environmental Health
Control of Osteoblast and Oteoclast Function through Cellular Adhesion to Bone Marrow Cells.
- Principal Investigator
  
  MORIMOTO Isao
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  University of Occupational and Environmental Health
Induction of Expression of MHC-class-II Antigen on Human Thyroid Carcinoma by Wild-Type p53
- Principal Investigator
  
  FUJIHIRA Takashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  University of Occupational and Environmental Health
Regulation of bone turnover by adjusting signal transduction
- Principal Investigator
  
  NAKAMURA Toshitka
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  University of Occupational and Environmental Health
Heparan sulfate proteoglycan on leukemic cells is primarily involved in integrin-triggering and its mediated adhesion to endothelial cells.Principal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational & Environmental Health (U.O.E.H.)
Escape from Inhibition of Liver Regeneration in Fibrotic Liver through The Modulation of Extracellular Matrix.
- Principal Investigator
  
  YAMADA Shinwa
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Occupational and Environmental Health
Effects of abnormalities of adhesion molecule on T-cell function in HIV-infected patients.
- Principal Investigator
  
  ODA Susumu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health
Studies on the hyperferritinemia in adult Still's disease ; Origin of the increased serum ferritin and possible pathophysiological property of the increased ferritin
- Principal Investigator
  
  OTA Toshiyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational and Environmental Health (UOEH)
Adhesion molecules and soluble factors specifically regulate T lymphocyte function in patients with rheumatoid arthritis.Principal Investigator
- Principal Investigator
  
  TANAKA Yoshiya
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  University of Occupational & Environmental Health (U.O.E.H.)
Inhibition of Rejection Reaction by Modulating Actions of Adhesion Molecules on Sinusoidal Endothelial Cells in Rat Liver Allograft.
- Principal Investigator
  
  YAMADA Shinwa
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Occupational & Environmental Health (U.O.E.H.)

[Book] 最新の骨粗鬆学（第２版）2023
- Author(s)
  山形薫、田中良哉
- Total Pages
  7
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08536
[Book] 最新の骨粗鬆症学（第２版）2023
- Author(s)
  山形薫、田中良哉
- Total Pages
  7
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08536
[Book] 最新関節リウマチ学（第２版）2022
- Author(s)
  山形薫、田中良哉
- Total Pages
  6
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08536
[Book] 動物／疾患モデルの作製技術・病態解析・評価手法関節リウマチにおける最新メカニズム、創薬応用と動物評価試験。2017
- Author(s)
  山形薫、中山田真吾、田中良哉。
- Total Pages
  428
- Publisher
  技術情報協会
- ISBN
  9784861046650
- Data Source
  KAKENHI-PROJECT-16K09914
[Book] 動物／疾患モデルの作製技術・病態解析・評価手法：関節リウマチにおける動物モデルの作製手法。2017
- Author(s)
  山形薫、中山田真吾、張香梅、田中良哉。
- Total Pages
  428
- Publisher
  技術情報協会
- ISBN
  9784861046650
- Data Source
  KAKENHI-PROJECT-16K09914
[Book] ステロイドの副作用と対策. 今日の治療指針　2013年版━私はこう治療している.2013
- Author(s)
  田中　良哉
- Total Pages
  1890
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22249025
[Book] ファーマナビゲーター,リウマチ～生物学的製剤編単独投与、抗リウマチ薬(MTX)の併用との使い分けのコツありますか2010
- Author(s)
  山岡邦宏, 田中良哉
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21591275
[Book] 関節リウマチ〜新しい治療、正しい知識で克服する〜2009
- Author(s)
  田中良哉
- Total Pages
  128
- Publisher
  岩波書店
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Extracting immunological and clinical heterogeneity across autoimmune rheumatic diseases by cohort-wide immunophenotyping2023
- Author(s)
  Tanaka Hiroaki、Okada Yukinori、Nakayamada Shingo、Miyazaki Yusuke、Sonehara Kyuto et al.
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 83 Issue: 2 Pages: 242-252
- DOI
  10.1136/ard-2023-224537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14451, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-23K24465
[Journal Article] B cell activation via immunometabolism in systemic lupus erythematosus2023
- Author(s)
  Shigeru Iwata, Maiko Hajime Sumikawa, Yoshiya Tanaka
- Journal Title
  
  Frontiers in immunology
  
  Volume: 14 Pages: 1155421-1155421
- DOI
  10.3389/fimmu.2023.1155421
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08574
[Journal Article] Reduced homovanillic acid, SDF-1α and SCGF-β levels in cerebrospinal fluid are related to depressive states in systemic lupus erythematosus2023
- Author(s)
  Yuya Fujita
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 62 Issue: 10 Pages: 3490
- DOI
  10.1093/rheumatology/kead091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08525, KAKENHI-PROJECT-22K08574
[Journal Article] DOCK2 is involved in the host genetics and biology of severe COVID-192022
- Author(s)
  Namkoong Ho、et al.
- Journal Title
  
  Nature
  
  Volume: 609 Issue: 7928 Pages: 754-760
- DOI
  10.1038/s41586-022-05163-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08606, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-20H03684, KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-20K16453
[Journal Article] A Case of Simultaneous Onset of Highly Active Systemic Lupus Erythematosus and IgG4-Related Renal Disease2022
- Author(s)
  Fujita Yuya、Iwata Shigeru、Nakano Kazuhisa、Nakayamada Shingo、Miyazaki Yusuke、Kawabe Akio、Korekoda-Yoshinari Hiroko、Nawata Aya、Tanaka Yoshiya
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: - Issue: 2 Pages: 178-182
- DOI
  10.1093/mrcr/rxac002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Nailfold microvascular abnormalities are associated with a higher prevalence of pulmonary arterial hypertension in patients with MCTD2022
- Author(s)
  Todoroki Yasuyuki、Kubo Satoshi、Nakano Kazuhisa、Miyazaki Yusuke、Ueno Masanobu、Satoh-Kanda Yurie、Kanda Ryuichiro、Miyagawa Ippei、Hanami Kentaro、Nakatsuka Keisuke、Saito Kazuyoshi、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: Mar 14:keac165 Issue: 12 Pages: 4875-4884
- DOI
  10.1093/rheumatology/keac165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] Enhancer RNA commits osteogenesis via microRNA-3129 expression in human bone marrow-derived mesenchymal stem cells.2022
- Author(s)
  Nguyen AP, Yamagata K, Iwata S, Trimova G, Zhang T, Shan Y, Nguyen MP, Sonomoto K, Nakayamada S, Kato S, Tanaka Y.
- Journal Title
  
  Inflamm Regen
  
  Volume: 42 Issue: 1 Pages: 43-54
- DOI
  10.1186/s41232-022-00228-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08536
[Journal Article] IL-6 production through repression of UBASH3A gene via epigenetic dysregulation of super-enhancer in CD4+ T cells in rheumatoid arthritis.2022
- Author(s)
  Yamagata K, Nakayamada S, Zhang T, Nguyen AP, Ohkubo N, Iwata S, Kato S, Tanaka Y.
- Journal Title
  
  Inflamm Regen
  
  Volume: 42 Issue: 1 Pages: 46-59
- DOI
  10.1186/s41232-022-00246-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08536
[Journal Article] Association of Viral Infection With the Development and Pathogenesis of Systemic Lupus Erythematosus2022
- Author(s)
  Iwata Shigeru、Tanaka Yoshiya
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9
- DOI
  10.3389/fmed.2022.849120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Eosinophilic granulomatosis with polyangiitis exhibits T cell activation and IgG4 immune response in the tissue; comparison with IgG4-related disease2022
- Author(s)
  Kubo Satoshi、Kanda Ryuichiro、Nawata Aya、Miyazaki Yusuke、Kawabe Akio、Hanami Kentaro、Nakatsuka Keisuke、Saito Kazuyoshi、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  RMD Open
  
  Volume: 8 Issue: 1 Pages: e002086-e002086
- DOI
  10.1136/rmdopen-2021-002086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force2022
- Author(s)
  Wang Qingbo S.、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4830-4830
- DOI
  10.1038/s41467-022-32276-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08606, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-20H03684, KAKENHI-PROJECT-19K08650, KAKENHI-PROJECT-20K16453, KAKENHI-PROJECT-20K17460
[Journal Article] An enhanced mitochondrial function through glutamine metabolism in plasmablast differentiation in systemic lupus erythematosus2022
- Author(s)
  Maiko Hajime Sumikawa, Shigeru Iwata, Mingzeng Zhang, Hiroko Miyata, Masanobu Ueno, Yasuyuki Todoroki, Atsushi Nagayasu, Ryuichiro Kanda, Koshiro Sonomoto, Keiichi Torimoto, Seunghyun Lee, Shingo Nakayamada, Kazuo Yamamoto, Yosuke Okada, Yoshiya Tanaka
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 7 Pages: 1-11
- DOI
  10.1093/rheumatology/keab824
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-20K17524, KAKENHI-PROJECT-21K20884
[Journal Article] TGF-β3 in differentiation and function of Tph-like cells and its relevance to disease activity in patients with systemic lupus erythematosus.2022
- Author(s)
  Shan Y, Nakayamada S, Nawata A, Yamagata K, Sonomoto K, Tanaka H, Satoh-Kanda Y, Nguyen MP, Todoroki Y, Nagayasu A, Ueno M, Kanda R, Fujita Y, Zhang T, Hao H, Zhou J, Ma X, Anan J, Nguyen AP, Tanaka Y.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: keac646. Issue: 7 Pages: 2464-2474
- DOI
  10.1093/rheumatology/keac646
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08536, KAKENHI-PROJECT-20K08815
[Journal Article] Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component2022
- Author(s)
  Shirai Y, Nakanishi Y, Suzuki A, Konaka H, Nishikawa R, Sonehara K, Namba S, Tanaka H, Masuda T, Yaga M, Satoh S, Izumi M, Mizuno Y, Jo T, Maeda Y, Nii T, Oguro-Igashira E, Morisaki T, Kam, Nakayamada S, Nishigori C, Tanaka Y, Takeda Y, Yamamoto K, Kumanogoh A, Okada Y, The Biobank Japan Project
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 81 Issue: 9 Pages: 1301-1312
- DOI
  10.1136/annrheumdis-2022-222460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00476, KAKENHI-PROJECT-19K08650
[Journal Article] pstein-Barr virus-induced gene 3 commits human mesenchymal stem cells to differentiate into chondrocytes via endoplasmic reticulum stress sensor.2022
- Author(s)
  Zhang T, Yamagata K, Iwata S, Sonomoto K, Trimova G, Nguyen AP, Hao H, Shan Y, Nguyen MP, Nakayamada S, Tanaka Y.
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 12 Pages: e0279584-e0279584
- DOI
  10.1371/journal.pone.0279584
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08536
[Journal Article] Role of DNA dioxygenase Ten-Eleven translocation 3 (TET3) in rheumatoid arthritis progression.2022
- Author(s)
  Kawabe A, Yamagata K, Kato S, Nakano K, Sakata K, Tsukada YI, Ohmura K, Nakayamada S, Tanaka Y.
- Journal Title
  
  Arthritis Research Therapy
  
  Volume: 24 Issue: 1 Pages: 222-222
- DOI
  10.1186/s13075-022-02908-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08534, KAKENHI-PROJECT-22K08536
[Journal Article] Efficacy and safety of high-dose of mycophenolate mofetil compared with cyclophosphamide pulse therapy as induction therapy in Japanese patients with proliferative lupus nephritis2021
- Author(s)
  Ohkubo Naoaki、Iwata Shigeru、Nakano Kazuhisa、Miyagawa Ippei、Hanami Kentaro、Fukuyo Shunsuke、Miyazaki Yusuke、Kawabe Akio、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  Modern Rheumatology
  
  Volume: - Issue: 6 Pages: 1077-1085
- DOI
  10.1093/mr/roab113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-19K08926
[Journal Article] T helper cells expressing fractalkine receptor and bearing T follicular helper 1-like cell functions in patients with IgG4-related disease.2021
- Author(s)
  Inoue Y, Nakayamada S, Kubo S, Yamagata K, Sonomoto K, Iwata S, Miyazaki Y, Tanaka Y.
- Journal Title
  
  Rheumatology (Oxford)
  
  Volume: 未定 Issue: 9 Pages: 3854-3863
- DOI
  10.1093/rheumatology/keab935
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-22K08536
[Journal Article] Involvement of lncRNA IL21-AS1 in interleukin-2 and T follicular regulatory cell activation in systemic lupus erythematosus.2021
- Author(s)
  Hao H, Nakayamada S, Ohkubo N, Yamagata K, Zhang M, Shan Y, Iwata S, Zhang T, Tanaka Y.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 23 Issue: 1 Pages: 302-312
- DOI
  10.1186/s13075-021-02682-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-20K08815
[Journal Article] IL-2 drives conversion of T follicular helper cells to T follicular regulatory cells through transcriptional regulation in systemic lupus erythematosus.2021
- Author(s)
  Hao H, Nakayamada S, Yamagata K, Ohkubo N, Iwata S, Inoue Y, Zhang M, Zhang T, Kanda Satoh Y, Shan Y, Otsuka T, Tanaka Y.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 73 Issue: 1 Pages: 132-142
- DOI
  10.1002/art.41457
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-20K08815
[Journal Article] ヒトB細胞分化におけるアミノ酸を介した免疫代謝機構の解明～SLE新規治療の創出～2021
- Author(s)
  岩田　慈, 田中　良哉
- Journal Title
  
  アレルギーの臨床.
  
  Volume: 41(2) Pages: 50-54
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Neuropsychiatric systemic lupus erythematosus detected using extravascular spillage signal on dynamic magnetic resonance imaging (Ktrans)2021
- Author(s)
  Fujita Yuya、Iwata Shigeru、Nakano Kazuhisa、Adachi Hiroaki、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: 61 Issue: SI Pages: SI102-SI104
- DOI
  10.1093/rheumatology/keab757
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] mTOR activation in CD8+ cells contributes to disease activity of rheumatoid arthritis and increases therapeutic response to TNF inhibitors2021
- Author(s)
  Zhang Mingzeng、Iwata Shigeru、Sonomoto Koshiro、Ueno Masanobu、Fujita Yuya、Anan Junpei、Miyazaki Yusuke、Ohkubo Naoaki、Sumikawa Maiko Hajime、Todoroki Yasuyuki、Miyata Hiroko、Nagayasu Atsushi、Kanda Ryuichiro、Hao He、Trimova Gulzhan、Lee Seunghyun、Nakayamada Shingo、Sakata Kei、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: - Issue: 7 Pages: 3010-3022
- DOI
  10.1093/rheumatology/keab834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Pathological role of activated mTOR in CXCR3+ memory B cells of rheumatoid arthritis.2021
- Author(s)
  Iwata S, Zhang M, Hajime M, Ohkubo N, Sonomoto K, Torimoto K, Kitanaga Y, Trimova G, Todoroki Y, Miyata H, Ueno M, Nagayasu A, Kanda R, Nakano K, Nakayamada S, Sakata K, Tanaka Y.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: in press Issue: 11 Pages: 5452-5462
- DOI
  10.1093/rheumatology/keab229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Efficacy and safety of belimumab during maintenance therapy in patients with systemic lupus erythematosus2021
- Author(s)
  Miyazaki Yusuke、Nakayamada Shingo、Sonomoto Koshiro、Kawabe Akio、Inoue Yoshino、Okubo Naoaki、Iwata Shigeru、Hanami Kentaro、Tanaka Yoshiya
- Journal Title
  
  Rheumatology
  
  Volume: Dec 28:keab953. Issue: 9 Pages: 3614-3626
- DOI
  10.1093/rheumatology/keab953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] 自己免疫疾患におけるB細胞の役割と新規治療戦略2021
- Author(s)
  岩田　慈, 田中　良哉
- Journal Title
  
  医学のあゆみ
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Human dendritic cell-derived osteoclasts with high bone resorption capacity and T cell stimulation ability.2021
- Author(s)
  Narisawa M, Kubo S, Okada Y, Yamagata K, Nakayamada S, Sakata K, Yamaoka K, Tanaka Y.
- Journal Title
  
  Bone.
  
  Volume: 142 Pages: 115616-115616
- DOI
  10.1016/j.bone.2020.115616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-18K16164
[Journal Article] Therapeutic perspectives on the metabolism of lymphocytes in patients with rheumatoid arthritis and systemic lupus erythematosus2021
- Author(s)
  Shigeru Iwata, Yoshiya Tanaka
- Journal Title
  
  Expert Rev Clin Immunol.
  
  Volume: 17 Issue: 10 Pages: 1121-1130
- DOI
  10.1080/1744666x.2021.1964957
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] The additive effects of hydroxychloroquine to maintenance therapy with standard of care in patients with systemic lupus erythematosus.2020
- Author(s)
  Miyagawa I, Nakano K, Nakayamada S, Iwata S, Hanami K, Fukuyo S, Kubo S, Kawabe A, Miyazaki Y, Inoue Y, Ueno M, Ohkubo N, Fujita Y, Tanaka Y.
- Journal Title
  
  Int J Rheum Dis.
  
  Volume: 23(4) Issue: 4 Pages: 549-558
- DOI
  10.1111/1756-185x.13792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] Clinical aspects in patients with rheumatoid arthritis complicated with lymphoproliferative disorders without regression after methotrexate withdrawal and treatment for arthritis after regression of lymphoproliferative disorders.2020
- Author(s)
  Nakano K, Saito K, Nawata A, Hanami K, Kubo S, Miyagawa I, Fujino Y, Nakayamada S, Tanaka Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 27 Issue: 1 Pages: 1-7
- DOI
  10.1080/14397595.2020.1741870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] IL-23 drives expansion of Th17 cells through epigenetic regulation by signal transducer and activators of transcription 3 in lupus patients.2020
- Author(s)
  Lee S, Nakayamada S, Kubo S, Yamagata K, Yoshinari H, Tanaka Yoshiya.
- Journal Title
  
  Rheumatology (Oxford).
  
  Volume: 59 Issue: 10 Pages: 3058-3069
- DOI
  10.1093/rheumatology/keaa176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08925
[Journal Article] Tumour necrosis factor alpha promotes secretion of 14-3-3η by inducing necroptosis in macrophages2020
- Author(s)
  Trimova G, Yamagata K, Iwata S, Hirata S, Zhang T, Uemura F, Satoh M, Biln N, Nakayamada S, Maksymowych WP, Tanaka Y
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 22 Issue: 1 Pages: 24-24
- DOI
  10.1186/s13075-020-2110-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07940, KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-19K08617
[Journal Article] Methionine commits cells to differentiate into plasmablasts through epigenetic regulation of BTB and CNC homolog 2 by the methyltransferase enhancer of zeste homolog 2.2020
- Author(s)
  Zhang M, Iwata S, Hajime M, Ohkubo N, Todoroki Y, Miyata H, Ueno M, Hao H, Zhang T, Fan J, Nakayamada S, Yamagata K, Tanaka Y.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: － Issue: 7 Pages: 1143-1153
- DOI
  10.1002/art.41208
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900, KAKENHI-PROJECT-19K08925
[Journal Article] Critical Roles of Super-enhancers in the Pathogenesis of Autoimmune Diseases.2020
- Author(s)
  Yamagata K, Nakayamada S, Tanaka Y.
- Journal Title
  
  Inflamm Regen.
  
  Volume: 40 Issue: 1 Pages: 16-16
- DOI
  10.1186/s41232-020-00124-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08925
[Journal Article] 5-year remission rate after the discontinuation of adalimumab in patients with rheumatoid arthritis: Long-term follow-up results of the HONOR study.2020
- Author(s)
  Yamaguchi A, Hirata S, Kubo S, Fukuyo S, Hanami K, Nakano K, Nakayamada S, Saito K, Tanaka Y.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 15 Issue: 5 Pages: 1-8
- DOI
  10.1080/14397595.2019.1702141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] A case of eosinophilic granulomatosis with polyangiitis as a mimicker of IgG4-related disease2020
- Author(s)
  Kanda Ryuichiro、Kubo Satoshi、Nakano Kazuhisa、Kawabe Akio、Nawata Aya、Hanami Kentaro、Nakayamada Shingo、Tanaka Yoshiya
- Journal Title
  
  Modern Rheumatology Case Reports
  
  Volume: 4 Issue: 2 Pages: 278-282
- DOI
  10.1080/24725625.2020.1759200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08926
[Journal Article] Enhanced Fatty Acid Synthesis Leads to Subset Imbalance and IFN-γ Overproduction in T Helper 1 Cells2020
- Author(s)
  Iwata Shigeru、Zhang Mingzeng、Hao He、Trimova Gulzhan、Hajime Maiko、Miyazaki Yusuke、Ohkubo Naoaki、Satoh Kanda Yurie、Todoroki Yasuyuki、Miyata Hiroko、Ueno Masanobu、Nagayasu Atsushi、Nakayamada Shingo、Sakata Kei、Tanaka Yoshiya
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 593103-593103
- DOI
  10.3389/fimmu.2020.593103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08900
[Journal Article] Glycolaldehyde-modified advanced glycation end-products inhibit differentiation of human monocytes into osteoclasts via upregulation of IL-10.2019
- Author(s)
  Tanaka K, Yamagata K, Kubo S, Nakayamada S, Sakata K, Matsui T, Yamagishi SI, Okada Y, Tanaka Y.
- Journal Title
  
  Bone
  
  Volume: 128 Pages: 115034-115034
- DOI
  10.1016/j.bone.2019.115034
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08925, KAKENHI-PROJECT-19K17995
[Journal Article] IL-6 and sIL-6R induces STAT3-dependent differentiation of human VSMCs into osteoblast-like cells through JMJD2B-mediated histone demethylation of RUNX2.2019
- Author(s)
  Kurozumi A, Nakano K, Yamagata K, Okada Y, Nakayamada S, Tanaka Y.
- Journal Title
  
  Bone
  
  Volume: 124 Pages: 53-61
- DOI
  10.1016/j.bone.2019.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08925
[Journal Article] Soluble IL-6R promotes chondrogenic differentiation of mesenchymal stem cells to enhance the repair of articular cartilage defects using a rat model for rheumatoid arthritis.2019
- Author(s)
  Yamagata K, Nakayamada S, Zhang T, Zhang X, Tanaka Y.
- Journal Title
  
  Clin Exp Rheumatol.
  
  Volume: －
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08925
[Journal Article] Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System.2018
- Author(s)
  Kubo S, Nakayamada S, Sakata K, Kitanaga Y, Ma X, Lee S, Ishii A, Yamagata K, Nakano K, Tanaka Y.
- Journal Title
  
  Front Immunol
  
  Volume: 9 Pages: 1510-1510
- DOI
  10.3389/fimmu.2018.01510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09914
[Journal Article] Relevance of interferon-gamma in pathogenesis of life-threatening rapidly progressive interstitial lung disease in patients with dermatomyositis.2018
- Author(s)
  Ishikawa Y, Iwata S, Hanami K, Nawata A, Zhang M, Yamagata K, Hirata S, Sakata K, Todoroki Y, Nakano K, Nakayamada S, Satoh M, Tanaka Y.
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 20 Issue: 1 Pages: 240-240
- DOI
  10.1186/s13075-018-1737-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09914, KAKENHI-PROJECT-16K09915
[Journal Article] Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair.2018
- Author(s)
  Yamagata K, Nakayamada S, Tanaka Y.
- Journal Title
  
  Inflamm Regen
  
  Volume: 38 Issue: 1 Pages: 4-4
- DOI
  10.1186/s41232-018-0061-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09914
[Journal Article] Expansion of T follicular helper-T helper 1 like cells through epigenetic regulation by signal transducer and activator of transcription factors2018
- Author(s)
  Ma X, Nakayamada S, Kubo S, Sakata K, Yamagata K, Miyazaki Y, Yoshikawa M, Kitanaga Y, Zhang M, Tanaka Y.
- Journal Title
  
  Annals of Rheumatic Diseases
  
  Volume: 88 Issue: 9 Pages: 1354-1361
- DOI
  10.1136/annrheumdis-2017-212652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10010, KAKENHI-PROJECT-16K09914
[Journal Article] Induction of Regulatory T Cells and Its Regulation with Insulin-like Growth Factor/Insulin-like Growth Factor Binding Protein-4 by Human Mesenchymal Stem Cells.2017
- Author(s)
  Miyagawa I, Nakayamada S, Nakano K, Yamagata K, Sakata K, Yamaoka K, Tanaka Y.
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 5 Pages: 1616-1625
- DOI
  10.4049/jimmunol.1600230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09914
[Journal Article] Spontaneous differentiation of human mesenchymal stem cells on poly-lactic-co-glycolic acid nano-fiber scaffold2016
- Author(s)
  Koshiro Sonomoto, Kunihiro Yamaoka, Hiroaki Kaneko, Kaoru Yamagata, Kei Sakata, Xiangmei Zhang, Masahiro Kondo, Yukichi Zenke, Ken Sabanai, Shingo Nakayamada, Akinori Sakai, Yoshiya Tanaka
- Journal Title
  
  PLOS ONE
  
  Volume: in press Issue: 4 Pages: e0153231-e0153231
- DOI
  10.1371/journal.pone.0153231
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860821, KAKENHI-PROJECT-15K10499, KAKENHI-PROJECT-16K09914
[Journal Article] リウマチ・膠原病の治療の現況と将来展望—分子標的治療薬を中心に−2014
- Author(s)
  高崎芳成、竹内勤、田中良哉
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 189-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Janus kinase (JAK) inhibitors in rhematoid arthritis2014
- Author(s)
  Yamaoka K, Tanaka Y
- Journal Title
  
  Curr Rheumatol Rev
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Clinical Significance of Epithelial-Mesenchymal Transition-Associated Markers in Malignant Pleural Mesothelioma2014
- Author(s)
  Iwanami T, Uramoto H, Nakagawa M, Shimokawa H, Yamada S, Kohno K, Tanaka F
- Journal Title
  
  Oncology.
  
  Volume: 86(2) Pages: 109-116
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 骨と関節リウマチ2014
- Author(s)
  田中良哉
- Journal Title
  
  腎と骨代謝
  
  Volume: 27 Pages: 121-128
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 炎症性疾患と骨代謝：　分子標的薬を中心に2014
- Author(s)
  田中良哉
- Journal Title
  
  実験医学
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 関節リウマチに於ける臓器障害2014
- Author(s)
  田中良哉
- Journal Title
  
  日本医師会雑誌
  
  Volume: 142 Pages: 2241-2244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] リウマチ・膠原病に於ける分子標的治療の最前線　序論2014
- Author(s)
  田中良哉
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 189-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 関節X線による関節損傷評価2014
- Author(s)
  田中良哉
- Journal Title
  
  カレントテラピー
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Role of JAKs in myeloid cells and autoimmune diseases.2014
- Author(s)
  Kubo S, Yamaoka K, Tanaka Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: in press
- NAID
  130004943841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 生物学的製剤による関節疾患治療2014
- Author(s)
  田中良哉
- Journal Title
  
  Clinical Calcium
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] ベリムマブ：ループス腎炎2014
- Author(s)
  田中良哉
- Journal Title
  
  腎と透析
  
  Volume: 76 Pages: 96-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Jak/Stat now2014
- Author(s)
  田中良哉、山岡邦宏
- Journal Title
  
  分子リウマチ治療
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 濾胞性ヘルパーT（Tfh）細胞と自己免疫疾患2014
- Author(s)
  中山田真吾、田中良哉
- Journal Title
  
  最新医学
  
  Volume: 34 Pages: 12-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] トファシチニブの課題2014
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  臨床リウマチ
  
  Volume: 26 Pages: 17-23
- NAID
  130005072309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] インフリキシマブ2014
- Author(s)
  齋藤和義、田中良哉
- Journal Title
  
  Mebio（
  
  Volume: 31(5) Pages: 14-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 生物学的製剤2014
- Author(s)
  田中良哉
- Journal Title
  
  Osteoporosis Japan
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 生物学的製剤2014
- Author(s)
  田中良哉
- Journal Title
  
  医学のあゆみ
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] The non-canonical wnt5a/rors signaling pathway in bone metabolism.2014
- Author(s)
  Sonomoto K, Yamaoka K, Tanaka Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] : Clinical Significance of Epithelial-Mesenchymal Transition-Associated Markers in Malignant Pleural Mesothelioma.2014
- Author(s)
  Iwanami T, Uramoto H, Nakagawa M, Shimokawa H, Yamada S, Kohno K, Tanaka F.
- Journal Title
  
  Oncology
  
  Volume: 86(2) Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬2014
- Author(s)
  田中良哉
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 285-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬2014
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  最新医学
  
  Volume: 60 Pages: 285-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬：　使い方と安全性2014
- Author(s)
  田中良哉
- Journal Title
  
  Mebio
  
  Volume: 31（５） Pages: 74-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] リウマチ・膠原病の治療の現況と将来展望　–分子標的治療薬を中心に−2014
- Author(s)
  高崎芳成、竹内勤、田中良哉
- Journal Title
  
  最新医学
  
  Volume: 60 Pages: 191-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Syk/Btk標的治療2014
- Author(s)
  中山田真吾、田中良哉
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 280-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] RAにおける抗BAFF抗体tabalumabの有効性と安全性2014
- Author(s)
  齋藤和義、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 51 Pages: 118-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 生物学的製剤ゴリムマブがもたらす新展開〜寛解導入と維持の実践〜2013
- Author(s)
  田中良哉
- Journal Title
  
  臨床リウマチ
  
  Volume: 25 Pages: 276-280
- NAID
  130005086106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Is it possible to withdraw biologics from therapy in rheumatoid arthritis?2013
- Author(s)
  Tanaka Y, Hirata S
- Journal Title
  
  Clinical Therapeutics
  
  Volume: 35 Pages: 2028-2035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 新世代の経口抗リウマチ薬　–トファシチニブの有効性と安全性2013
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  薬事
  
  Volume: 55 Pages: 1527-1530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Systemic lupus erythematosus患者に於けるdeabetes mellitus発症についての検討　-3施設共同研究-2013
- Author(s)
  今村秀基、中塚敬輔、吾妻妙子、山崎政治、小辻英明、吉田泰憲、浦本秀隆、小山倫浩、田中良哉
- Journal Title
  
  臨床と研究
  
  Volume: 90 Pages: 1389-1392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 細胞内シグナル分子を標的にしたRA骨破壊制御2013
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  Rheumatology Clinical Research
  
  Volume: 2 Pages: 104-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Th1細胞とTfh細胞の多様性/可塑性とエピゲネティクス制御2013
- Author(s)
  中山田真吾、田中良哉
- Journal Title
  
  臨床免疫
  
  Volume: 59 Pages: 500-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 新世代の経口抗リウマチ薬−トファニチニブの有効性と安全性2013
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  薬事
  
  Volume: 55 Pages: 1527-1530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 新たな作用機序を有する骨粗鬆症、リウマチ治療薬2013
- Author(s)
  田中良哉
- Journal Title
  
  実験医学
  
  Volume: 31 Pages: 877-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] SLEの新たな治療標的2013
- Author(s)
  齋藤和義、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 50 Pages: 583-590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] ヒト間葉系幹細胞による破骨細胞の分化抑制作用と関節リウマチ治療への応用2013
- Author(s)
  園本格子朗、田中良哉.
- Journal Title
  
  産業医科大学雑誌
  
  Volume: 35 Pages: 33-37
- NAID
  110009593199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] MBDAスコアによるRA活動性評価2013
- Author(s)
  平田信太郎、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 50 Pages: 618-622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] A Jak inhibitor tofacitinib for the treatment of rheumatoid arthritis from basic to clinic.2013
- Author(s)
  Tanaka Y, Yamaoaka K
- Journal Title
  
  Mod Rheumatol
  
  Volume: 23 Pages: 415-424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Janus kinase inhibitors in autoimmune diseases2013
- Author(s)
  O’Shea JJ, Kontzias A, Yamaoka K, Tanaka Y, Laurence A.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] ドパミン受容体シグナルによる破骨細胞の分化制御2013
- Author(s)
  花見健太郎、中野和久、田中良哉
- Journal Title
  
  日本臨床免疫学会会誌
  
  Volume: 36 Pages: 35-39
- NAID
  10031157133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] RA患者滑膜細胞におけるDNAメチル化2013
- Author(s)
  中野和久、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 50 Pages: 370-375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬と関節リウマチ2013
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 43 Pages: 247-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 免疫学からみた骨代謝2013
- Author(s)
  田中良哉
- Journal Title
  
  Clinical Calcium
  
  Volume: 23 Pages: 1265-1270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions2013
- Author(s)
  Smolen JS, Tanaka Y, et al.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72 Pages: 482-492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 発熱と倦怠感が主訴のリウマチ治療中の男性、鑑別診断は？2013
- Author(s)
  田中良哉
- Journal Title
  
  Rheumatology Clinical Research
  
  Volume: 2 Pages: 153-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] MTX+TNF阻害薬による治療2013
- Author(s)
  齋藤和義、田中良哉
- Journal Title
  
  Arthritis
  
  Volume: 11 Pages: 104-113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 2013年欧州リウマチ学会議（EULAR）2013
- Author(s)
  田中良哉
- Journal Title
  
  Arthritis
  
  Volume: 11 Pages: 208-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] polymyositis/dermatomyositisおよびsystemic sclerosis患者に於けるdeabetes mellitus発症についての検討　-3施設共同研究-2013
- Author(s)
  今村秀基、中塚敬輔、吾妻妙子、山崎政治、小辻英明、吉田泰憲、浦本秀隆、小山倫浩、田中良哉
- Journal Title
  
  臨床と研究
  
  Volume: 90 Pages: 1101-1104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 関節リウマチのゲノムワイドDNAメチル化解析2013
- Author(s)
  中野和久、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 49 Pages: 589-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 低分子化合物を用いた細胞内シグナル分子を標的とする治療2013
- Author(s)
  田中良哉
- Journal Title
  
  最新医学
  
  Volume: 68 Pages: 692-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Discontinuation of biologics in patients with rheumatoid arthritis2013
- Author(s)
  Tanaka Y, Hirata S, Saleem B, Emery P
- Journal Title
  
  Clin Exp Rheumatol
  
  Volume: 31(Suppl. 78)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 中枢神経ループスの診断と治療2013
- Author(s)
  田中良哉
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 65 Pages: 1255-1267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 臨床的寛解の判定基準を教えて下さい2013
- Author(s)
  平田信太郎、田中良哉
- Journal Title
  
  Arthritis
  
  Volume: 25 Pages: 276-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Rheumatoid arthritis患者に於ける糖尿病発症についての検討　-3施設共同研究-2013
- Author(s)
  今村秀基、中塚敬輔、吾妻妙子、山崎政治、小辻英明、吉田泰憲、浦本秀隆、小山倫浩、田中良哉
- Journal Title
  
  臨床と研究
  
  Volume: 90 Pages: 811-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 関節リウマチ患者の実態調査〜アンメットメディカルニーズの把握2013
- Author(s)
  田中良哉
- Journal Title
  
  新薬と臨床
  
  Volume: 62 Pages: 758-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Dopamine D2-like receptor signaling suppresses human osteoclastogenesis2013
- Author(s)
  Hanami K, Nakano K, Saito K, Okada Y, Yamaoka K, Kubo S, Kondo M, Tanaka Y
- Journal Title
  
  Bone
  
  Volume: 56 Pages: 1-8
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Next stage of RA treatment: TNF-inhibitor-free remission will be a possible treatment goal ?2013
- Author(s)
  Tanaka Y
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] IL-17 inhibits chondrogenic differentiation of human mesenchymal stem cells2013
- Author(s)
  Kondo M, Yamaoka K, Sonomoto K, Fukuyo S, Oshita K, Okada Y, Tanaka Y
- Journal Title
  
  Plos ONE
  
  Volume: 8(11)
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-_Y and IL-17 production by human CD4+ T cells2012
- Author(s)
  Maeshima K, Yamaoaka K, Kubo S, Nakano K, Iwata S, Tanaka Y, et al
- Journal Title
  
  Arthritis Rheum
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-γ and IL-17 production by human CD4+ T cells.2012
- Author(s)
  Maeshima K, Yamaoaka K Kubo s, Nakano K, Iwata S, Saito K, Ohishi M, Miyahara H, Tanaka S, Ishi K, Yoshimatsu H, Tanaka Y.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 1790-1798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Janus kinase (JAK)阻害薬tofacitinibの作用機序と自己免疫疾患治療薬への可能性2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 47 Pages: 97-100
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] B-cell or T-cell-dominant recurrence after rituximab therapy in patients with SLE2012
- Author(s)
  Iwata S, Saito K, Tokunaga M, Tanaka Y
- Journal Title
  
  Ann Rheum Dis
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Anti-rheumatic effect of JAK inhibitors2012
- Author(s)
  Yamaoka K., Maeshima K., Kubo S., Sonomoto K., Tanaka Y.
- Journal Title
  
  Jpn J Clin.Immunol
  
  Volume: 35 Pages: 112-117
- NAID
  10030573749
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Effect of COX-2 selective inhibitor celecoxib on upper gastrointestinal symptoms in patients with rheumatoid arthritis-Evaluation of switch from non-steroidal anti-inflammatory drugs2012
- Author(s)
  Hirata S., Saito K., Sawamukai N., Nakano K., Yamaoka K., Tanaka Y.
- Journal Title
  
  Kyushu J Rheumatol
  
  Volume: 32 Pages: 17-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation2012
- Author(s)
  Iwata S, Yamaoka K, Niiro H, Nakano K, Wang S-P, Akashi K, Tanaka Y
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: (in press)
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Cell autonomous role of TGFss and IL-2 receptor in CD4+ and CD8+ inducible regulatory T cell generation during graft-versus-host disease2012
- Author(s)
  Sawamukai N, Satake A, Schmidt AM, Lamborn IT, Tanaka Y, Kambayashi T
- Journal Title
  
  Boold
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK-Statシグナル伝達経路を介したIL-10の産生制御2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 Pages: 470-474
- NAID
  40019309840
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Churg-Strauss syndrome complicated by bilateral central retinal artery occlusion2012
- Author(s)
  Katsuyama T., Saito K., Yamaoka K, Hirata S., Tsujimura S., Nawata M., Tanaka Y.
- Journal Title
  
  Kyushu J Rheumatol
  
  Volume: 32 Pages: 52-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] L-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt5a/Ror2 pathway.2012
- Author(s)
  Sonomoto K, Yamaoka K, Oshita K, Fukuyo S, Zhang X, Nakano K, Okada Y, Tanaka Y.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 3355-3363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医薬ジャーナル
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Mesenchymal stem cells : A new treatment tool for rheumatoid arthritis2012
- Author(s)
  Sonomoto K., Yamaoka K., Tanaka Y.
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: (In press)
- NAID
  130004482298
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Efficacy and safety of ocrelizumab in patients with active rheuamatoid arthritis with an inadequate response to at least one TNF inhibitor : results from the phase III SCRIPT trial2012
- Author(s)
  Tak PP, Mease PJ, Genovese MC, Kremer J, Haraoui B, Tanaka Y, Bingham III CO, et al
- Journal Title
  
  Arthritis Rheum
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Regulation of inflammation through JAK3-Stat6 pathway in dendritic cells2012
- Author(s)
  Yamaoka K, Maeshima K, Kubo S, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 35 Pages: 62-68
- NAID
  10030465675
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2012
- Author(s)
  Tanaka Y, Maeshima K, Yamaoka K
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71(Supp II)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] JAK3の発見から臨床応用まで2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  炎症と免疫
  
  Volume: 20 Pages: 268-271
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation.2012
- Author(s)
  Iwata S, Yamaoka K, Niiro H, Nakano K, Wang S-P, Akashi K, Tanaka Y.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 129 Pages: 1594-1601
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬tofacitinibの抗リウマチ作用2012
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医学のあゆみ
  
  Volume: 240 Pages: 562-566
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-〓 and IL-17 production by human CD4+ T cells2012
- Author(s)
  Maeshima K, Yamaoaka K, Kubo S, Nakano K, Iwata S, Saito K, Ohishi M, Miyahara H, Tanaka S, Ishi K, Yoshimatsu H, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Postmarketing Surveillance of Tocilizumab for Rheumatoid Arthritis in Japan-Interim Analysis of 3,881 Patients2012
- Author(s)
  Koike T, Harigai M, Inokuma S, Ishiguro N, Ryu J, Tanaka Y, Ito K, et al
- Journal Title
  
  Ann Rheum Dis
  
  Volume: (in press)
- NAID
  120003660599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] ヒトB細胞活性化におけるSykを介したTLR9シグナルの増幅メカニズム2012
- Author(s)
  岩田慈、山岡邦宏、新納宏昭、赤司浩一、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: (In press)
- NAID
  130006947788
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Involvement of Syk in pathology of systemic autoimmune disease2012
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 35 Pages: 56-61
- NAID
  10030465649
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN- □ and IL-17 production by human CD4+ T cells2012
- Author(s)
  Maeshima K, Yamaoaka K Kubo s, Nakano K, Iwata S, Saito K, Ohishi M, Miyahara H, Tanaka S, Ishi K, Yoshimatsu H, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 1790-1798
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation2012
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  J Allergy and Clinical Immunology
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis.2012
- Author(s)
  Tanaka Y, Maeshima Y, Yamaoaka K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2012
- Author(s)
  Tanaka Y, Maeshima Y, Yamaoaka K
- Journal Title
  
  Ann Rheum Dis
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] 樹状細胞におけるJAK3-Stat6を介した炎症制御機構2012
- Author(s)
  山岡邦宏、久保智史、前島圭佑、田中良哉
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 Pages: 264-268
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] ヒト間葉系幹細胞による破骨細胞の活性制御2012
- Author(s)
  尾下浩一、山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: (In press)
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] IL-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt5a/Ror2 pathway2012
- Author(s)
  Sonomoto K, Yamaoka K, Oshita K, Fukuyo S, Zhang X, Nakano K, Okada Y, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: 64 Pages: 3353-3363
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] JAK阻害薬の有用性は?2012
- Author(s)
  前島圭佑、山岡邦宏、石井宏治、田中良哉
- Journal Title
  
  内科
  
  Volume: 109 Pages: 664-666
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Anti-rheumatic effect of JAK inhibitors2012
- Author(s)
  Yamaoka K, Maeshima K, Kubo S, Sonomoto K, Tanaka Y
- Journal Title
  
  Jpn J Clin. Immunol
- NAID
  10030573749
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Golimumab, a human anti-TNF-α monoclonal antibody, injected subcutaneously every 4 weeks in Japanese patients with active rheumatoid arthritis in combination with methotrexate : results of the Phase 2/3, multicenter, randomized, double-blind, placebo-controUed GO-FORTH study through 24 weeks2012
- Author(s)
  Tanaka Y, Harigai M, Takeuchi T, Yamanaka H, Ishiguro N, Yamamoto K, et al
- Journal Title
  
  Ann Rheum Dis
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy2012
- Author(s)
  Mori H., Okada Y., Yamaoka K., Tanaka Y.
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 30 Pages: 114-118
- NAID
  10031168760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Clinical, radiographic, and functional effectiveness of tocilizumab for rheumatoid arthritis patients-REACTION 52-week study-2012
- Author(s)
  Takeuchi T, Tanaka Y, Amano K, Hoshi D, Nawata M, Nagasawa H, et al
- Journal Title
  
  Rheumatology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011
- Author(s)
  Iwata S, Saito K, Tokunaga M, Yamaoka K, Nawata M, Yukawa S, Hanami K, Fukuyo S, Kubo S, Miyagawa I, Tanaka Y
- Journal Title
  
  Journal of Rheumatology 38(4)
  
  Pages: 633-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] JAK inhibitor : tofacitinib, a new disease modifying anti-rheumatic drug2011
- Author(s)
  Yamaoka K, Kubo S, Sonomoto K, Maeshima K, Tanaka Y
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: 31 Pages: 349-353
- NAID
  130004482280
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] In vitro and in vivo analysis of a Jak inhibitor in rheumatoid arthritis2011
- Author(s)
  Tanaka Y., Maeshima K., Yamaoka K.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 71
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Phenotypic Changes of Lymphocytes in Patients with Systemic Lupus Erythematosus who are in the long-term remission After B Cell Depletion Therapy with Rituximab2011
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  J Rheumatol
  
  Volume: 38 Pages: 633-641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-cells and a D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model2011
- Author(s)
  Nakano K, Yamaoka K, Hanami K, Saito K, Sasaguri Y, Yanagihara N, Tanaka S, Katsuki I, Matsushita S, Tanaka Y
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 3745-3752
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Jak and Syk : Emerging their relevance to the treatment of inflammatory diseases2011
- Author(s)
  Tanaka Y, Iwata S, Yamaoka K
- Journal Title
  
  Inflammation and Regeneration Journal
  
  Volume: 31 Pages: 237-44
- NAID
  130004943791
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production2011
- Author(s)
  Oshita K, Yamaoka K, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 1658-1667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase(JAK) inhibitors in rheumatoid arthritis2011
- Author(s)
  Yamaoka K, Tanaka Y
- Journal Title
  
  Curr Rheum Rev
  
  Volume: 7 Pages: 306-312
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase (JAK)特異的阻害薬の効果に基づく作用機序の検討2011
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  リウマチ科
  
  Volume: 46 Pages: 84-88
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Lower osteocalcin and osteopontin contents of the femoral head in hip fracture patients than osteoarthritis patients2011
- Author(s)
  Tanaka S, Narusawa K, Onishi H, Miura M, Hijioka A, Kanazawa Y, Nishida S, Ikeda S, Nakamura T
- Journal Title
  
  Osteoporos Int.
  
  Volume: 22 Pages: 587-597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Pericarditis induced by prophylactic administration of isoniazid in a patient with rheumatoid arthritis2011
- Author(s)
  Kubo S, Yamaoka K, Saito K, Tanaka Y
- Journal Title
  
  Joint Bone spine
  
  Volume: 78 Pages: 99-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behcet's disease2011
- Author(s)
  Iwata S, Yamaoka K, Tanaka Y
- Journal Title
  
  Mod Rheumatol
  
  Volume: 21 Pages: 184-191
- NAID
  10029361883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Janus kinase (JAK) inhibitors in rheumatoid arthritis2011
- Author(s)
  Yamaoka K., Tanaka Y.
- Journal Title
  
  Curr Rheum Rev
  
  Volume: 7 Pages: 306-312
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Cytokine-mediated signals as targets for treatment of rheumatoid arthritis : a JAK inhibitor in vitro and in vivo2011
- Author(s)
  Tanaka Y, Yamaoka K
- Journal Title
  
  Int J Clin Rheumatol
  
  Volume: 6 Pages: 439-4444
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production2011
- Author(s)
  Oshita K, Yamaoka K, Udagawa N, Fukuyo S, Sonomoto K, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Pages: 1658-1667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptor on CD4 naive T-cells and a D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model2011
- Author(s)
  Nakano K, Yamaoka K, Tanaka Y
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 3745-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Efficacy of combination therapy of anti-TNF-α antibody infliximab and methotrexate in refractory entero-Behcet's disease.2011
- Author(s)
  Iwata S, Saito K, Yamaoka K, Tsujimura S, Nawata M, Hanami K, Tanaka Y
- Journal Title
  
  Mod Rheumatol. 21(2)
  
  Pages: 184-91
- NAID
  10029361883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] 細胞内シグナル分子を標的とした治療:JAK2011
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  最新医学
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] A JAK inhibitor tofacitinib regulates synovitis through inhibition of IFN-・and IL-17 production by human CD4+T cells2011
- Author(s)
  Maeshima K, Yamaoka K, Tanaka Y
- Journal Title
  
  Arthritis Rheum
  
  Volume: (In press) Issue: 6 Pages: 1790-1798
- DOI
  10.1002/art.34329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Advanced glycation end products increase endothelial permeability through RAGE/Rho signaling pathway.2010
- Author(s)
  Hirose A, Tanikawa T, Mori H, Okada Y, Tanaka Y
- Journal Title
  
  FEBS Letters 584
  
  Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Involvement of mast cells in systemic sclerosis2010
- Author(s)
  Yukawa S, Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn. J. Clin. Immunol
  
  Volume: 33 Pages: 81-86
- NAID
  10027753435
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Lin H-S.Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipolysaccharide-stimulated NF-κB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic Ell cells.2010
- Author(s)
  Choo Q-Y, Ho PC, Tanaka Y
- Journal Title
  
  Rheumatology
  
  Volume: 49 Pages: 1447-1460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Discontinuation of infliximab after attaining low disease activity in patienis with rheumatoid arthritis, RRR (remission induction by remicade in RA) study.2010
- Author(s)
  Tanaka Y, Takeuchi T, Mimori T, Saito K, Nawata M, Kameda H, Nojima T, Miyasaka N, Koike T.
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 69 Pages: 1286-1291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] A calcineurin inhibitor, tacrolimus overcomes treatment-unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis.2010
- Author(s)
  Suzuki K, Saito K, Tsujimura S, Nakayamada S, Yamaoka K, Sawamukai N, Iwata S, Nawata M, Tanaka Y.
- Journal Title
  
  J Rheumatol
  
  Volume: 37 Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Tacrolimus, a calcineurin inhibitor, overcomes treatment unresponsiveness mediated by P-glycoprotein on lymphocytes in refractory rheumatoid arthritis.2010
- Author(s)
  Suzuki K, Saito K, Tsujimura S, Nakayamada S, Yamaoka K, Sawamukai N, Iwata S, Nawata M, Nakano K, Tanaka Y
- Journal Title
  
  J Rheumatol. 37(3)
  
  Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Deficiency of vitamin A delays bone healing process in association with reduced BMP2 expression after drill-hole injury in mice.2010
- Author(s)
  Tanaka K, Nakamura T, et al.
- Journal Title
  
  Bone
  
  Volume: 47 Pages: 1006-1012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling.2010
- Author(s)
  Sawamukai N, Yukawa s, Saito K, Nakayamada S, Kambayashi T, Tanaka Y.
- Journal Title
  
  Arthritis Rheum
  
  Volume: 62 Pages: 952-959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling.2010
- Author(s)
  Sawamukai N, Yukawa s, Saito K, Nakayamada S, Kambayashi T, Tanaka Y.
- Journal Title
  
  Arthritis Rheum (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Galectin-9 induces osteoblast differentiation through the CD44/Smad signaling pathway.2010
- Author(s)
  Tanikawa R, Tanikawa T, Hirashima M, Yamauchi A, Tanaka Y
- Journal Title
  
  Biochem Biophys Res Commun 394
  
  Pages: 317-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Etanercept overcomes P-glycoprotein-induced drug resistance in lymphocytes of patients with intractable rheumatoid arthritis.2010
- Author(s)
  Tsujimura S, Saito K, Nakayamada S, Tanaka Y
- Journal Title
  
  Modern Rheumatology 20(2)
  
  Pages: 139-146
- NAID
  10027168842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] C5a promotes migration, proliferation, and vessel-formation in endothelial cells2010
- Author(s)
  Kurihara R, Yamaoka K, Tanaka Y
- Journal Title
  
  Inflamm Res
  
  Volume: 59 Pages: 659-666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis, RRR (remission induction by remicade in RA) study.2010
- Author(s)
  Tanaka Y, Takeuchi T, Mimori T, Saito K, Nawata M, Kameda H, Nojima T, Miyasaka N, Koike T.
- Journal Title
  
  Ann Rheum Dis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] シグナル伝達分子を標的とした関節リウマチ治療:新規抗リウマチ薬の可能性2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  医学のあゆみ 230
  
  Pages: 786-791
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Dopamine released by dendritic cells polarizes Th2 differentiation.2009
- Author(s)
  Nakano K, Higashi T, Tanaka Y, (他3名、5番目)
- Journal Title
  
  Int Immunol 21
  
  Pages: 645-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Jak阻害の特異性と関節リウマチに対する治療効果2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  感染・炎症・免疫 39
  
  Pages: 63-65
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak inhibitor ; possibility and mechanism as a new disease modifying anti-rheumatic drug2009
- Author(s)
  Yamaoka K, Tanaka Y
- Journal Title
  
  Jpn J Clin Immunol
  
  Volume: 32 Pages: 85-91
- NAID
  10024962052
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Jak3阻害2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  炎症と免疫 17
  
  Pages: 524-529
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Effects of anti-TNF-alpha antibody infliximab in refractory entero-Behcet's disease.2009
- Author(s)
  Iwata S, Saito K, Yamaoka K, Tsujimura S, Nawata M, Suzuki K, Tanaka Y
- Journal Title
  
  Rheumatology 48(8)
  
  Pages: 1012-1013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591179
[Journal Article] Usefulness of initial histological features for stratifying Sjogren's syndrome responders to mizoribine.2009
- Author(s)
  Nakayamada S, Fujimoto T, Tanaka Y, (他3名、3番目)
- Journal Title
  
  Rheumatology 48
  
  Pages: 1279-1282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Advanced glycation end products induce calcification of vascular smooth muscle cells through RAGE/p38 MAPK.2009
- Author(s)
  Tanikawa T, Okada Y, Tanikawa R, Tanaka Y
- Journal Title
  
  J Vascular Res 46
  
  Pages: 572-580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] RAにおけるチロシンキナーゼ阻害薬の役割2009
- Author(s)
  山岡邦宏、田中良哉
- Journal Title
  
  Frontiers in Rheuma& Clinlmmunol 3
  
  Pages: 32-36
- NAID
  40017004423
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] Selective cyclooxygenase-2 inhibitor prevents reduction of trabecular bone mass in collagen-induced arthritic mice in association with suppression of RANKL/OPG ratio and IL-6 mRNA expression In synovial tissue but not in bone marrow cells.2008
- Author(s)
  Taketa T, Sakai A, Tanaka S, Nakai K, Menuki K, Yamane H, Tanaka K, Nakamura T
- Journal Title
  
  J Bone Miner Metab 26
  
  Pages: 143-151
- NAID
  10024126399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese.2008
- Author(s)
  Mototani H, Iida A, Nakajima M, Furuichi T, Miyamoto Y, Tsunoda T, Sudo A, Kotani A, Uchida A, Ozaki K, Tanaka Y, Nakamura Y, Tanaka T, Notoya K, Ikegawa S.
- Journal Title
  
  Hum Mol Gene 17
  
  Pages: 1790-1797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Overcoming drug resistance induced by P-glycoprotein on lymphocytes in patients with refractory rheumatoid arthritis.2008
- Author(s)
  Tsujimura S, Saito K, Nawata M, Nakayamada S, Tanaka Y.
- Journal Title
  
  Ann Rheum Dis 67
  
  Pages: 189-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Interaction of galectin-9 with lipid rafts induces osteoblast proliferation through the c-Src/ERK signaling pathway.2008
- Author(s)
  Tanikawa R, Okada Y, Nakano K, Tnikawa t, Hirashima M, Yaraauchi A, Hosokawa R, Tanaka Y.
- Journal Title
  
  J Bone Miner Res 23
  
  Pages: 278-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Post-marketing surveillance of the safety profile of infliximab in 5, 000 Japanese patients with rheumatoid arthritis.2008
- Author(s)
  Takeuchi T, Tatsuki T, Nogami N, Ishiguro N, Tanaka Y, Yamanaka H, Harigai M, Ryu J, Inoue K, Kondo H, Inokuma S. Kamatani N, Ochi T, Koike T.
- Journal Title
  
  Ann Rheum Dis 67
  
  Pages: 189-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Antagonizing dopamine D1-like receptor inhibits Th17 cell differentiation : Preventive and therapeutic effects on experimental autoimmune encephalomyelitis2008
- Author(s)
  Nakano K, Higashi T, Hashimoto K, Takagi R, Tanaka Y, Matsushida S
- Journal Title
  
  Biochem Biophy Res Commun 286-291
  
  Pages: 373-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Alendronate protects premenopausal women from bone loss and fracture associated with high-dose glucocorticoid therapy.2008
- Author(s)
  Okada Y, Nawata M, Nakayamada S, Saito K, Tanaka Y
- Journal Title
  
  J Rheumatol 35
  
  Pages: 2249-2254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Reduced progression to type 2 diabetes from impaired glucose tolerance after a 2-day in-hospital diabetes educational program : the Joetsu Diabetes Prevention Trial.2008
- Author(s)
  Kawahara T, Takahashi K, Inazu T, Arao T, Kawahara C, Tabata T, Moriyama H, Okada Y, Morita E, Tanaka Y
- Journal Title
  
  Diabetes Care 31
  
  Pages: 1949-1954
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Genetic disruption of all nitric oxide synthase is isoforms enhances BMD and bone turnover in mice in vivo : Involvement of the rennin-angiotensin system.2008
- Author(s)
  Sabanai K, Tsutsui M, Sakai A, Hirasawa H, Tanaka S, Nakamura E, Nakamura T, et al.
- Journal Title
  
  J Bone Miner Res 23
  
  Pages: 633-643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Increased esophageal mucosal/submucosal blood flow in patients with gastroesophageal reflux disease : Normalization by treatment with a proton pump inhibitor.2008
- Author(s)
  Mine S, Iida T, Tabata T, Okada Y, Tanaka Y
- Journal Title
  
  J Gastroenterol Hepatol 23
  
  Pages: 303-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Interaction of galectin-9 with lipid rafts induces osteoblast proliferation through the c-Src/ERK signaling pathway.2008
- Author(s)
  Tanikawa R, Tanikawa T, Okada Y, Nakano K, Hirashima M, Yamauchi A, Hosokawa R, Tanaka Y
- Journal Title
  
  J Bone Miner Res 23
  
  Pages: 278-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Induction of hyperadiponectinemia following long-term treatment of patients with rheumatoid arthritis with infliximab (IFX), an anti-TNF-alpha antibody.2008
- Author(s)
  Nishida K, Okada Y, Nawata M, Saito K, Tanaka Y
- Journal Title
  
  Endocrine J 20
  
  Pages: 213-216
- NAID
  10021265093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Commencing use of alendronate protects premenopausal women from bone loss and fracture associated with high-dose glucocorti coid therapy.2008
- Author(s)
  Okada Y, Nawata M, Nakayamada S, Saito K, Tanaka Y.
- Journal Title
  
  J Rheumatol 35
  
  Pages: 2249-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Antagonizing dopamine D1-like receptor inhibits Th17 cell differentiation : Preventive and therapeutic effects on experimental autoimmune encephalomyelitis.2008
- Author(s)
  Nakano K, Higashi T, Hashimoto K, Takagi R, Tanaka Y, Matsushida S.
- Journal Title
  
  Biochem Biophy Res Commun 373
  
  Pages: 286-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Arsenic trioxide augments chk2/p53-mediated apoptosis by inhibiting oncogene wip1 phosphatase.2008
- Author(s)
  Yoda A, Toyoshima K, Onishi N, Hazaka Y, Tsukuda Y, Tsukada J, Kondo T, Tanaka Y, Minami Y.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 18969-18979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] 診療controversy-medical decision makingのために-若年者におけるステロイド誘発性骨粗鬆症のマネージメント : ビスホスフォネートの立場から2006
- Author(s)
  田中良哉
- Journal Title
  
  内科 98
  
  Pages: 897-901
- Data Source
  KAKENHI-PROJECT-18591129
[Journal Article] Osteoblasts and osteoclasts in bone remodeling and inflammation.2005
- Author(s)
  Tanaka Y, et al.
- Journal Title
  
  Current Drug Targets-Inflammation & Allergy 4
  
  Pages: 325-328
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591074
[Journal Article] Osteoblasts and osteoclasts in bone remodeling and inflammation.2005
- Author(s)
  Tanaka Y, et al.
- Journal Title
  
  Current Drug Targets- Inflammation & Allergy 4
  
  Pages: 325-328
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591074
[Journal Article] Phenotypic changes of lymphocytes in patients with systemic lupus eryth ematosus who are in longterm remission after B cell depletion therapy with rtuximab.
- Author(s)
  Iwata S, Saito K, Tokunaga M, Yamaoka K, Nawata M, Yukawa S, Hanami K, Fukuyo S, Miyagawa I, Kubo S, Tanaka Y.
- Journal Title
  
  J Rheumatol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Amplification of toll-like receptor-mediated signaling through Syk in human B cell activation
- Author(s)
  Iwata S., Yamaoka K, Niiro H., Nakano K., Wang SP., Akashi K., Tanaka Y.
- Journal Title
  
  J Allergy and Clinical Immunology
  
  Volume: (In press)
- NAID
  40019337340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591275
[Journal Article] The JAK inhibitor tofacitinib reduces the T cell stimulatory capacity of human monocyte-derived dendritic cells
- Author(s)
  Kubo S, Yamaoka K, Kondo M, Yamagata K, Zhao J, Iwata S, Tanaka Y
- Journal Title
  
  Ann Rheum Dis
  
  Volume: (in press)
- NAID
  110010039749
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis, RRR (remission induction by remicade in RA) study.
- Author(s)
  Tanaka Y, Takeuchi T, Mimori T, Saito K, Nawata M, Kameda H, Nojima T, Miyasaka N, KoikeT.
- Journal Title
  
  Ann Rheum Dis (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteop rotegerin production.
- Author(s)
  Oshita K, Yamaoka K, Udagawa N, Fukuyo S, Sonomoto K, Maeshima K, Kurihara R, Nakano K, Saito K, Okada Y, Chiba K, Tanaka Y.
- Journal Title
  
  Arthritis Rheum
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Dopamine induces IL-6-dependent IL-17 production via D1-like receptoron CD4 nalve T-cells and a D1-like receptor antagonist SCH-23390 inhibits cartilage destruction in a human rheumatoid arthritis/SCID mouse chimera model.
- Author(s)
  Nakano K, Yamaoka K, Hanami K, Saito K, Sasaguri Y, Yanagihara N, Tanaka S, Katsuki I, Matsushita S, Tanaka Y.
- Journal Title
  
  J Immunol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249025
[Journal Article] Marked improvement of calcinosis in adult dermatomyositis with etidronate therapy.
- Author(s)
  Mori H, Okada Y, Yamaoka K, Saito K, Tanaka Y
- Journal Title
  
  J Bone Miner Metab (in press)
- NAID
  10031168760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Journal Article] Mast cell-derived tryptase inhibits apoptosis of human rheumatoid synovial fibroblasts via rho-mediated signaling.
- Author(s)
  Sawamukai N, Yukawa s, Saito K, Nakayamada S, Kambayashi T, Tanaka Y.
- Journal Title
  
  Arthritis Rheum (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18209026
[Journal Article] Human mesenchymal stem cells inhibit osteoclastogenesis through osteoprotegerin production.
- Author(s)
  Oshita K, Yamaoka K, Udagawa N, Fukuyo S, Sonomoto K, Maeshima K, Kurihara R, Nakano K, Saito K, Okada Y, Chiba K, Tanaka Y
- Journal Title
  
  Arthritis Rheum (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591105
[Patent] 軟骨組織修復方法2019
- Inventor(s)
  田中良哉、山形薫、中山田真吾
- Industrial Property Rights Holder
  田中良哉、山形薫、中山田真吾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-119273
- Filing Date
  2019
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-19K08925
[Patent] 軟骨組織修復方法2016
- Inventor(s)
  田中良哉、中山田真吾、山形薫
- Industrial Property Rights Holder
  田中良哉、中山田真吾、山形薫
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-119273
- Filing Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K09914
[Patent] Aktシグナル経路の活性化阻害を目的として使用するレフルノミド2005
- Inventor(s)
  澤向範文、田中良哉
- Industrial Property Rights Holder
  澤向範文、田中良哉
- Industrial Property Number
  2005-081972
- Filing Date
  2005
- Acquisition Date
  2005
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] 関節リウマチ関連間質性肺疾患患者における胸部CT定量評価による肺容積減少に関連する因子の探索2023
- Author(s)
  川口貴子、田原正浩、山﨑啓、神田友梨恵、田中良哉、矢寺和博
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K07333
[Presentation] IL-6シグナルの活性化によりヒト脂肪組織由来間葉系幹細胞は遅筋型筋芽細胞へ効率的に分化する2023
- Author(s)
  山形　薫、大塚　隆史、岡田　洋右、中山田　真吾、田中　良哉
- Organizer
  第8回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] MicroRNA-3129がもたらすヒト骨髄由来間葉系幹細胞の骨形成におけるスーパーエンハンサーの機能的役割2023
- Author(s)
  山形薫, Nguyen Phuong Anh, 中山田真吾, 加藤茂明, 田中良哉
- Organizer
  第41回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] MicroRNA-3129が担うヒト骨髄由来間葉系幹細胞の骨形成におけるスーパーエンハンサーの機能的役割2023
- Author(s)
  山形薫、Nguyen Phuong Anh、中山田真吾、加藤茂明、田中良哉
- Organizer
  第8回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] ナノファイバーを用いた最適化間葉系幹細胞のラット生体内移植による関節軟骨の修復2023
- Author(s)
  山形薫、中山田真吾、近藤真弘、田中良哉
- Organizer
  第41回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] ヒト間葉系幹細胞の軟骨分化における細胞内Epstein-Barr virus-induced gene 3の重要な役割2023
- Author(s)
  山形薫、張童、中山田真吾、田中良哉
- Organizer
  第8回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] ヒト樹状細胞由来破骨細胞におけるサイトカイン遺伝子の発現様式とJAK阻害薬の作用2023
- Author(s)
  山形薫、中山田真吾、神田龍一郎、田中良哉
- Organizer
  第67回日本リウマチ学会総会・学術総会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] 高い骨吸収能とT細胞刺激能を有するヒト樹状細胞由来破骨細胞2022
- Author(s)
  山形　薫, 中山田　真吾, 成澤　学, 久保　智史, 岡田　洋右, 田中　良哉
- Organizer
  第8回骨免疫フォーラム
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] IL-6 production through repression of UBASH3A gene via epigenetic dysregulation of super-enhancer in CD4+ T cells in rheumatoid arthritis2022
- Author(s)
  山形薫, 中山田真吾, 張童, 加藤茂明, 田中良哉
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] IL-6シグナルはヒト脂肪組織由来間葉系幹細胞から骨格筋系譜細胞への分化を促進する2022
- Author(s)
  山形薫、大塚隆史、岡田洋右、中山田真吾、田中良哉
- Organizer
  第７回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] 進行性線維化を示す関節リウマチに伴う間質性肺疾患患者における肺機能低下に関連する因子の探索2022
- Author(s)
  川口貴子、田原正浩、山﨑啓、田中良哉、矢寺和博
- Organizer
  第31回Pneumo Forum
- Data Source
  KAKENHI-PROJECT-21K07333
[Presentation] Factors associated with pulmonary function decline in patients with rheumatoid arthritis related interstitial lung disease2022
- Author(s)
  Takako Kawaguchi, Masahiro Tahara, Kei Yamasaki, Yoshiya Tanaka, Kazuhiro Yatera
- Organizer
  The 62nd Annual Meeting of the Japanese Respiratory Society
- Data Source
  KAKENHI-PROJECT-21K07333
[Presentation] 高い骨吸収能とT細胞刺激能を備えたヒト樹状細胞由来破骨細胞2022
- Author(s)
  山形　薫, 中山田　真吾, 成澤　学, 久保　智史, 岡田　洋右, 山岡　邦宏, 田中　良哉
- Organizer
  第７回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-22K08536
[Presentation] RA患者におけるmTOR活性化CD8+細胞の病態への関与と生物学的製剤が与える影響2021
- Author(s)
  岩田慈、張明増、上野匡庸、藤田悠哉、隅川舞子、大久保直紀、轟泰幸、宮田寛子、永安敦、神田龍一郎、中野和久、中山田真吾、阪田圭、田中良哉
- Organizer
  第65回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] The relevance of mTOR activation in CD8+ cells to disease activity and therapeutic response to TNF inhibitor in patients with rheumatoid arthritis2021
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Koshiro Sonomoto, Masanobu Ueno, Yuya Fujita, Naoaki Ohkubo, Maiko Hajime, Yasuyuki Todoroki, Hiroko Miyata, Atsushi Nagayasu, Ryuichiro Kanda, Gulzhan Trimova, Shingo Nakayamada, and Yoshiya Tanaka
- Organizer
  第49回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Neuropsychiatric Systemic Lupus Erythematosus (NPSLE)の新規評価法確立に向けた取り組み～LOOPS registryから～2021
- Author(s)
  岩田慈, 藤田悠哉, 秀瀬真輔, 石渡小百合, 園本格士朗, 大久保直紀中野和久, 中山田真吾, 服部功太郎, 功刀浩, 吉村玲児, 田中良哉
- Organizer
  2021年日本生物学的精神医学会/日本神経精神薬理学会(合同年会)
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Factors associated with pulmonary function decline in patients with rheumatoid arthritis related interstitial lung disease2021
- Author(s)
  Takako Kawaguchi, Masahiro Tahara, Kei Yamasaki, Yoshiya Tanaka, Kazuhiro Yatera
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07333
[Presentation] 自己免疫疾患における免疫代謝機構を介したリンパ球分化・機能発現と病態への関与2021
- Author(s)
  岩田慈、田中良哉
- Organizer
  第49回臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] 全身性エリテマトーデス (SLE)におけるリンパ球免疫代謝異常と病態への関与2020
- Author(s)
  岩田慈、田中良哉
- Organizer
  第48回日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Role of amino acid cystine in cytotoxic effects of CD8+ cells and the relevance to pathological processes of rheumatoid arthritis2020
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Kazuhisa Nakano, Shingo Nakayamada, Kaoru Yamagata, Kei Sakjata and Yoshiya Tanaka
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Emerging role of epigenetic dysregulation of ubash3a in the pathogenesis of rheumatoid arthritis (RA)2020
- Author(s)
  Kaoru Yamagata, Shingo Nakayamada, Tong Zhang, Gulzhan Trimova, Phuong Anh Nguyen, Fumi Uemura, Ippei Miyagawa, Shigeru Iwata, Yoshiya Tanaka
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] The relevance of mTORC1-phosphorylated CXCR3+ memory B cells to the pathogenesis of rheumatoid arthritis2020
- Author(s)
  Shigeru Iwata, Mingzeng Zhang, Maiko Hajime, Naoaki Ohkubo, Yukihiro Kitanaga, Gulzhan Torimova, Kazuhisa Nakano, Shingo Nakayamada, Kaoru Yamagata, Kei Sakata and Yoshiya Tanaka
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] 関節リウマチ患者のCD4陽性T細胞におけるubash3a遺伝子のエピジェネティック制御と炎症誘導機構の解明2020
- Author(s)
  山形薫、中山田真吾、上村芙美、岩田慈、田中良哉
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] スーパーエンハンサー(SE)による関節リウマチ(RA)感受性遺伝子UBASH3A のエピジェネティック制御機構の解明2019
- Author(s)
  山形薫、中山田真吾、岩田慈、張童、トリモバグルズハン、グエンファンアン、上村芙美、宮川一平、加藤茂明、田中良哉
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] 必須アミノ酸メチオニンによるEZH2発現を介した形質芽細胞分化誘導とSLE病態への関与2019
- Author(s)
  張明増、岩田慈、元舞子、大久保直紀、轟泰幸、宮田　寛子、中山田真吾、山形薫、田中良哉
- Organizer
  日本臨床免疫学会 2019
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] Methionine commits immunometabolism and epigenetic regulation of BACH2 loci in B cells, resulting in biases toward plasmablast differentiation in the pathogenesis of SLE2019
- Author(s)
  Mingzeng Zhang, Shigeru Iwata, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Jie Fan, Shingo Nakayamada, Kaoru Yamagata and Yoshiya Tanaka
- Organizer
  American college of rheumatology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] TNF-ALPHA INDUCES NECROPTOSIS-LIKE DEATH OF MACROPHAGES AND PROMOTES EXTRACELLULAR RELEASE OF 14-3-3ETA2019
- Author(s)
  Gulzhan Trimova, Kaoru Yamagata, Shigeru Iwata, Tony Zhang, Fumi Uemura, Minoru Satoh, Michelle Zaharik, Norma Biln, Shintaro Hirata, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  Annual European Congress of Rheumatology EULAR 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] Massive in silico studies specified UBASH3A as a candidate pathogenic factor that is down-regulated in CD4+T cells of patients with rheumatoid arthritis (RA)2019
- Author(s)
  Kaoru Yamagata, Shingo Nakayamada, Ippei Miyagawa, Fumi Uemura, Shigeru Iwata, Yoshiya Tanaka
- Organizer
  第63回日本リウマチ　学会
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] Role of methionine and its transporter CD98 in human B cell differentiation and the relevance to pathological processes of SLE2019
- Author(s)
  Mingzeng Zhang, Shigeru Iwata, Maiko Hajime, Naoaki Ohkubo, Yasuyuki Todoroki, Hiroko Miyata, Jie Fan, Shingo Nakayamada, Kaoru Yamagata and Yoshiya Tanaka
- Organizer
  EAGOR 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] スーパーエンハンサーによる UBASH3A 遺伝子のエピジェネティック制御とその破綻による関節リウマチ (RA)病態形成2019
- Author(s)
  山形薫、中山田真吾、岩田慈、Nguyen Phuong Anh、上村芙美、張童、Gulzhan Trimova、吉成紘子、宮川一平、加藤茂明、田中良哉
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] Role of methionine in human B cell differentiation and the relevance to pathological processes of SLE2019
- Author(s)
  張明増、岩田慈、元舞子、大久保直紀、轟泰幸、宮田　寛子、中山田真吾、山形薫、田中良哉
- Organizer
  日本免疫毒性学会 2019
- Data Source
  KAKENHI-PROJECT-19K08900
[Presentation] ナノファイバーを用いた間葉系幹細胞生体内移植の最適化とEBI3による制御2019
- Author(s)
  山形薫、中山田真吾、張童、近藤真弘、岩田慈、田中良哉
- Organizer
  第37回日本骨代謝学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08925
[Presentation] Massive in silico studies identified UBASH3A as potential pathogenic factor that is dysregulated in CD4+ T cells of patients with rheumatoid arthritis2018
- Author(s)
  Kaoru Yamagata、Shingo Nakayamada、Ippei Miyagawa、Fumi Uemura、Sigeru Iwata、Shigeaki Kato、Yoshiya Tanaka
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] IL-6受容体はヒト間葉系幹細胞軟骨細胞分化を促進し、欠損関節軟骨の修復をもたらす2018
- Author(s)
  山形薫、中山田　真吾、張童、田中良哉
- Organizer
  第3回 United Front against Rheumatism
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] 可溶性IL-6受容体は間葉系幹細胞軟骨細胞分化を促進し、欠損関節軟骨の修復をもたらす2018
- Author(s)
  山形　薫、中山田　真吾、張　童、田中　良哉
- Organizer
  第36回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] Efficient regeneration of cartilaginous tissue after application of IL-6R-stimulated mesenchymal stem cells with a novel delivering scaffold for the treatment of RA2018
- Author(s)
  Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  第62回　日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] IL-6受容体は間葉系幹細胞軟骨細胞分化を促進し、損傷関節軟骨の修復をもたらす2018
- Author(s)
  山形　薫、中山田　真吾、張　童、田中　良哉
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] CD4陽性T細胞特異的に高発現するT細胞受容体（TCR）シグナル抑制因子UBASH3Aは関節リウマチ (RA)において発現が低下する2018
- Author(s)
  山形薫、中山田真吾、宮川一平、上村芙美、岩田慈、加藤茂明、田中良哉
- Organizer
  第4回　日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] IL-6受容体刺激間葉系幹細胞と乳酸グリコール酸共重合体の共移植による関節リウマチの軟骨破壊の修復と再生2017
- Author(s)
  山形　薫、中山田　真吾、近藤　真弘、田中　良哉
- Organizer
  第35回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] Efficient regeneration of cartilaginous tissue after application of IL-6R-stimulated mesenchymal stem cells with a novel delivering scaffold for the treatment of RA2017
- Author(s)
  Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka.
- Organizer
  第61回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] RA軟骨破壊の機序とその克服2017
- Author(s)
  山形薫, 中山田真吾, 近藤真弘, 中野和久, 田中良哉
- Organizer
  第61回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] Regeneration of cartilage tissue after application of IL-6R-treated mesenchymal stem cells with a novel delivering scaffold for the treatment of RA2017
- Author(s)
  Kaoru Yamagata, Shingo Nakayamada, Yoshiya Tanaka
- Organizer
  EAGOR2017
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] バイオマテリアルとIL-6受容体刺激間葉系幹細胞の共移植による関節リウマチの軟骨組織修復・再生の可能性2017
- Author(s)
  山形　薫、中山田　真吾、田中　良哉
- Organizer
  第3回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] IL-6受容体刺激間葉系幹細胞とバイオマテリアルの共移植による関節リウマチモデル動物の軟骨組織破壊の再生2017
- Author(s)
  山形　薫、中山田　真吾、近藤　真弘、田中　良哉
- Organizer
  第38回日本炎症再生医学会
- Data Source
  KAKENHI-PROJECT-16K09914
[Presentation] Estimation Of The Effect Of Denosumab On Bone Loss From The Results Of The 12-Month Phase II Study In Patients With Rheumatoid Arthritis (RA) On Background Methotrexate (MTX).2013
- Author(s)
  Yoshiya Tanaka, Tsutomu Takeuchi, Naoki Ishiguro, Hisashi Yamanaka, Toshiyuki Yoneda, Harry K. Genant and Desiree van der Heijde
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Comprehensive Disease Remission Achieved By Certolizumab Pegol Treatment, and Factors Associated With Certolizumab Pegol Comprehensive Disease Remission, In Rheumatoid Arthritis Patients With Predominantly High Disease Activity.2013
- Author(s)
  Yoshiya Tanaka, Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka, Naoki Ishiguro, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Mariko Kobayashi, Toshiharu Shoji, Nobuyuki Miyasaka and Takao Koike.
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] THE POSSIBILITY AND PREDICTIVE FACTORS OF MAINTAINING LOW DISEASE ACTIVITY AND JOINT STRUCTURE AFTER DISCONTINUATION OF INFLIXIMAB IN RA PATIENTS: RESULTS FROM 3-YEAR EXPERIENCE OF RRR STUDY2013
- Author(s)
  Y. Tanaka, T. Takeuchi, T. Mimori, N. Miyasaka, T. Koike, RRR study investigators.
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] GOLIMUMAB MONOTHERAPY IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS DESPITE DMARD THERAPY: WEEK 104 RESULTS OF CLINICAL, RADIOGRAPHIC AND SAFETY ASSESSMENTS INCLUDING EVALUATION OF REMISSION USING THE NEW ACR/EULAR CRITERIA2013
- Author(s)
  T. Takeuchi, M. Harigai, Y. Tanaka, H. Yamanaka, N. Ishiguro, K. Yamamoto, Y. Murakami, T. Yoshinari, D. Baker, N. Miyasaka, T. Koike
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Post–Hoc Analysis Showing Better Clinical Response With The Loading Dose Of Certolizumab Pegol In Japanese Patients With Active Rheumatoid Arthritis.2013
- Author(s)
  Tsutomu Takeuchi, Kazuhiko Yamamoto, Hisashi Yamanaka, Naoki Ishiguro, Yoshiya Tanaka, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Mariko Kobayashi, Toshiharu Shoji, Nobuyuki Miyasaka and Takao Koike.
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] WEEK 12 CLINICAL RESPONSE TO CERTOLIZUMAB PEGOL PREDICTS LONG-TERM OUTCOMES REGARDLESS OF CONCOMITANT MEDICATIONS AND BASELINE DISEASE CHARACTERISTICS IN JAPANESE PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS2013
- Author(s)
  H. Yamanaka, K. Yamamoto, T. Takeuchi, N. Ishiguro, Y. Tanaka, K. Eguchi, A. Watanabe, H. Origasa, T. Shoji, S. Onodera, N. Miyasaka.
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] ABATACEPT BIOLOGIC-FREE REMISSION STUDY IN ESTABLISHED RHEUMATOID ARTHRITIS PATIENTS ORION STUDY2013
- Author(s)
  T. Takeuchi, T. Matsubara, S. Ohta, M. Mukai, K. Amano, S. Tohma, Y. Tanaka, H. Yamanaka, N. Miyasaka, on behalf of ORION study group
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Efficacy Of Rituximab In Patients With Refractory Lupus Nephritis, a Post-Hoc Analysis From Phase II Trial In Japan2013
- Author(s)
  Yoshiya Tanaka, Kazuhiko Yamamoto, Tsutomu Takeuchi, Nobuyuki Miyasaka, Takayuki Sumida, Tsuneyo Mimori, Takao Koike and Kazuhiro Endo
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] MMUNOGENICITY OF CERTOLIZUMAB PEGOL WITHOUT CONCOMITANT METHOTREXATE AND CLINICAL RESPONSE IN RHEUMATOID ARTHRITIS PATIENTS: POST-HOC ANALYSIS OF THE HIKARI STUDY2013
- Author(s)
  T. Takeuchi, K. Yamamoto, H. Yamanaka, N. Ishiguro, Y. Tanaka, K. Eguchi, A. Watanabe, H. Origasa, Y. Wada, T. Shoji, N. Miyasaka, T. Koike.
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] CHARACTERISTICS ASSOCIATED WITH BETTER EFFECTIVENESS AND SAFETY IN RHEUMATOID ARTHRITIS PATIENTS TREATED WITH INTRAVENOUS TOCILIZUMAB: RESULTS FROM FULL ANALYSIS OF ALL-PATIENT POSTMARKETING SURVEILLANCE IN JAPAN2013
- Author(s)
  M. Harigai, S. Inokuma, N. Ishiguro, J. Ryu, T. Takeuchi, S. Takei, Y. Tanaka, H. Yamanaka, Y. Sano, H. Yaguramaki, T. Koike
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] EFFECTIVENESS OF ABATACEPT AGAINST RHEUMATOID ARTHRITIS IN DAILY CLINICAL PRACTICE - ORBIT STUDY2013
- Author(s)
  T Takeuchi, Y. Tanaka, K. Amano, J. Kikuchi, E. Tanaka, S. Hirata, H. Nagasawa, H. Yasuoka, H. Yamanaka.
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] GOLIMUMAB ADMINISTERED SUBCUTANEOUSLY EVERY FOUR WEEKS IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS DESPITE METHOTREXATE THERAPY: LONG-TERM CLINICAL, RADIOGRAPHIC AND SAFETY RESULTS, INCLUDING EVALUATION OF REMISSION USING THE NEW ACR/EULAR CRITERIA2013
- Author(s)
  Y. Tanaka, M. Harigai, T. Takeuchi, H. Yamanaka, N. Ishiguro, K. Yamamoto, Y. Murakami, T. Yoshinari, D. Baker, N. Miyasaka, T. Koike
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Economic Impact Of Adalimumab Treatment In Japanese Patients With Rheumatoid Arthritis: Analysis Of 24 Weeks Data From The Anouveau Study.2013
- Author(s)
  Yoshiya Tanaka, Yasuhiko Shinmura, Ryo Nakajima, Takahiro Muramatsu, Shuichi Komatsu, Tadamichi Kubo, Aki Kuroki, Ataru Igarashi, Toshiro Tango and Tsutomu Takeuchi.
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Safety and Effectiveness Of Abatacept In 3985 Japanese Patients With Rheumatoid Arthritis; Japan All-Cases Post-Marketing Surveillance2013
- Author(s)
  Takao Koike, Masayoshi Harigai, Naoki Ishiguro, Shigeko Inokuma, Junnosuke Ryu, Syuji Takei, Tsutomu Takeuchi, Y.Tanaka, Masahiko Watanabe and Hisashi Yamanaka
- Organizer
  第79回米国リウマチ学会 ACR 2013
- Place of Presentation
  米国(サンディエゴ)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] A LARGE-SCALE PROSPECTIVE SINGLE COHORT STUDY OF WORK PRODUCTIVITY AND ACTIVITY IMPAIRMENT IN JAPANESE PATIENTS WITH RHEUMATOID ARTHRITIS RECEIVING ADALIMUMAB: ANALYSIS OF 24-WEEKS DATA FROM THE ANOUVEAU STUDY2013
- Author(s)
  T Takeuchi, S. Komatsu, T. Muramatsu, T. Kubo, A. Kuroki, T. Tango, Y. Tanaka.
- Organizer
  The Annual European Congress of Rheumatology 2013
- Place of Presentation
  スペイン(マドリッド)
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] ドパミン受容体シグナルによる破骨細胞の分化制御2012
- Author(s)
  田中　良哉
- Organizer
  第33回　日本炎症・再生医学会
- Place of Presentation
  ホテル日航福岡(博多区(福岡))
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] The Maximization of Efficacy of Tocilizumab for the Treatment of Rheumatoid Arthritis.2012
- Author(s)
  Y Tanaka.
- Organizer
  The 8th International Congress on Autoimmunity
- Place of Presentation
  King Hosse in Bin Talal Convent Center(グラナダ(スペイン))
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] ドパミン受容体シグナルによる破骨細胞の分化制御メカニズムの解析2012
- Author(s)
  田中　良哉
- Organizer
  第３０回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(新宿区(東京))
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Discontinuation of Adalimumab without Functional and Radiographic Damage Progression After Achieving Sustained Remission in Patients with Rheumatoid Arthritis (the HONOR study): 1-Year Results.2012
- Author(s)
  Y Tanaka, S Hirata, S Fukuyo, M Nawata, S Kubo, K Yamaoka, K Saito.
- Organizer
  The 78th Annual Congress of American College of Rheumatology
- Place of Presentation
  Walter E. Washington(ワシントン(米国))
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] ドパミン受容体シグナルによる破骨細胞の分化制御2012
- Author(s)
  田中　良哉
- Organizer
  第４０回日本臨床免疫学会
- Place of Presentation
  京王プラザホテル(新宿区(東京))
- Invited
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Treatment of SLE with biologics. The 15th Congress of the Asia Pacific League of Associations for Rheumatology2012
- Author(s)
  Ｙ Tanaka
- Organizer
  APLAR 2012
- Place of Presentation
  Paseo del Vinlon(アンマン(ヨルダン)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] JAK-Statシグナル伝達経路阻害による抗炎症作用2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第29回日本骨代謝学会
- Place of Presentation
  大阪国際会議場(大阪)(招待講演)
- Year and Date
  2011-07-28
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] JAK-STATシグナル伝達経路阻害による炎症抑制作用2011
- Author(s)
  山岡邦宏、前島圭佑、久保智史、園本格士郎、湯川宗之助、岩田慈、田中伸哉、宮原寿明、田中良哉
- Organizer
  第32回日本炎症再生医学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] A JAK inhibitor, tofacitinib reduces IL-6 and matrix metalloproteinase-3 production in rheumatoid arthritis with suppressed cartilage destruction2011
- Author(s)
  Yamaoka K., Kubo S., Sonomoto K., Maeshima K., Tanaka Y.
- Organizer
  1st Bio-Rheumatology International Congress
- Place of Presentation
  ヒルトン東京ベイホテル(東京)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] In vitro and in vitro analysis of a Jak inhibitor in RA2011
- Author(s)
  Tanaka Y.
- Organizer
  Advances in Targeted Therapies
- Place of Presentation
  クロアチア(ドブロニク)(招待講演)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] リウマチ性疾患の治療の進歩-低分子化合物の可能性と作用機序2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第39回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル(東京)(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Is biologic-free remission possible in patients with RA?2011
- Author(s)
  Tanaka Y
- Organizer
  Advances in Targeted Therapies
- Place of Presentation
  クロアチア(ドブロニク)(招待講演)
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Next stage of RA treatment : bio-free remission will become a possible treatment goal-RRR study update2011
- Author(s)
  Tanaka Y
- Organizer
  The 5th Asian Congress on Autoimmunity
- Place of Presentation
  シンガポール,サンテック国際会議場(招待講演)
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] 次世代低分子化合物を用いた治療-JAK阻害薬2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第55回日本リウマチ学会総会学術集会
- Place of Presentation
  神戸ポートピアホテル(神戸)(招待講演)
- Year and Date
  2011-07-19
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Discontinuation of adalimumab after attaining remisison in patients with rheumatoid arthritis2011
- Author(s)
  Tanaka Y S.Hirata, M.Nawata, S.Kubo, K.Saito
- Organizer
  The Annual European Congress of Rheumatology
- Place of Presentation
  イギリス、ロンドン,ExCeL LONDON(招待講演)
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Tofacitinib reduces Interleukin-6 and Matrix Metalloproteinase-3 production and inhibits cartilage destruction in rheumatoid arthritis2011
- Author(s)
  Yamaoka K., Kubo S., Maeshima K., Sonomoto K., Nakano K., Sawamukai N., Iwata S., Nawata M., Saito K., Tanaka Y.
- Organizer
  American college of Rheumatology
- Place of Presentation
  McCormick Place West(シカゴ)
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] 低分子化合物を用いた治療の進歩2011
- Author(s)
  山岡邦宏、田中良哉
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル新高輪(東京)(招待講演)
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591275
[Presentation] Signal transduction inhibitors for the treatment of rheumatoid arthritis2011
- Author(s)
  Tanaka Y
- Organizer
  Bio-Rheumatology International Congress (BRIC) Tokyo, The 8th GARN Meeting
- Place of Presentation
  東京商工会議所(東京都)(招待講演)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-22249025
[Presentation] Humanized anti human Interlukin-6 receptor monoclonal antibody tocilizumab (TCZ) increases high molecular weight adiponectin (HMW-AN) in the patients with rheumatoid arthritis (RA) : result from The ESCORT study2010
- Author(s)
  Saito K, Hanami k, Nawata M, Yunoue N, Tanaka Y
- Organizer
  The 11th Annual European Congress of Rheumatology (EULAR)
- Place of Presentation
  Roma(Fiera Rome)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-20591179
[Presentation] ステロイド骨粗鬆症の病態と治療戦略～骨折予防を目指して～2010
- Author(s)
  岡田洋右、田中良哉
- Organizer
  日本骨代謝学会
- Place of Presentation
  大阪
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-20591105
[Presentation] Rheumatoid arthritis in the context of bone disease: a recent paradigm shift of the disease control.2009
- Author(s)
  Tanaka Y.
- Organizer
  The 6th International Bone Biology Forum
- Place of Presentation
  Susono
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] Discontinuation of infliximab therapy is possible after acquiring remission in patients with rhuematoid arthritis (RA): first report on RRR (remission induction by remicade in RA) study.2009
- Author(s)
  Y. Tanaka, T. Takeuchi, T. Mimori, N. Miyasaka, T. Koike.
- Organizer
  The Annual European Congress of Rheumatology 2009
- Place of Presentation
  Copenhagen
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] The oral Jak inhibitor CP-690, 550 in combination with methotrexate is efficacious, safe and well tolerated in Japanese patients with active rheumatoid arthritis with an inadequaet response to MTX alone.2009
- Author(s)
  Y. Tanaka, M. Suzuki, H. Nakamura, S. Toyoizumi, S.H. Zwillich.
- Organizer
  The Annual European Congress of Rheumatology 2009
- Place of Presentation
  Copenhagen
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] Discontinuation of infliximab after attaining low disease activity in patients with rheumatoid arthritis: an interim report on RRR (remission induction by remicade in RA) study.2009
- Author(s)
  Y. Tanaka, T. Takeuchi, T. Mimori, N. Miyasaka, T. Koike.
- Organizer
  The 73rd National Meeting of American college of Rheumatology
- Place of Presentation
  Philadelphia
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] Efficacy of a calcineurin-inhibitor tacrolimus on refractory interstitial pneumonitis complicated with connective tissue diseases.2008
- Author(s)
  Nakano K, Saito K, Yamaoka K, Sawamukai N, Tokunaga M, Nawata M, Iwata K, Suzuki K, Hanami K, Tanaka Y.
- Organizer
  EULAR 2008
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] A 2 year-extended follow-up of the phase I/II trial of rituximab for treatment of refractory systemic lupus erythematosus.2008
- Author(s)
  Tanaka Y, Yamamoto K, Takeuchi T, Nishimoto N, Miyasaka N, Sumida T, Sawda T, Kohsaka H, Matsumoto I, Saito K, Koike T.
- Organizer
  Annual European Congress of Rheumatology EULAR 2008
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] clinical and radiological remission of inflilximab for RA patients in Japan.2008
- Author(s)
  Tanaka Y, Takeuchi T, Mimori T, Miyasaka N, Koike T, Yamanaka H.
- Organizer
  The 13^<th> Asian Pacific League of Associations for Rheumatology (APLAR) Congress
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] TNF inhibitors for elderly patients with rheumatoid arthritis.2008
- Author(s)
  Tanaka Y, Nawata M, Iwata S, Yukawa S, Sawamukai N, Nakano K, Yamaoaka K, Saito K.
- Organizer
  The 13^<th> APLAR Congress
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-18209026
[Presentation] Different mechanisms are involved in different organ manifestation in SLE : learning from treatments with rituximab (anti-CD20) therapy.2008
- Author(s)
  Tanaka Y, Tokunaga M, Nawata M, Iwata S, Nakano K, Yamaoka K, Mima T, Nishimoto N, Saito K.
- Organizer
  The 72nd National Meeting of American college of Rheumatology
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-18209026

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Tanaka Yoshiya 田中 良哉

TANAKA Yoshiya 田中 良哉

田中 義哉 タナカ ヨシヤ

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Dynamics of stress-homeosurveillance and its relevance to disease controlPrincipal Investigator

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Tanaka Yoshiya 田中良哉

TANAKA Yoshiya 田中良哉

田中義哉タナカヨシヤ