NATSUME Atsushi 夏目敦至

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NATSUNE Atsushi 夏目敦至

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Researcher Number	30362255
Other IDs
Affiliation (Current)	2025: 名古屋大学, 未来社会創造機構, 特任教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 名古屋大学, 未来社会創造機構, 特任教授 2015 – 2022: 名古屋大学, 医学系研究科, 准教授 2016: 名古屋大学, 医学部, 准教授 2015: 名古屋大学, 大学院医学研究科, 准教授 2015: 名古屋大学, 大学院医学系研究科, 准教授 … More 2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 准教授 2013: 名古屋大学, 大学院脳神経外科学, 准教授 2009 – 2012: 名古屋大学, 医学系研究科, 准教授 2010 – 2011: 名古屋大学, 大学院・医学系研究科, 准教授 2009: Nagoya University, 医学系研究科, 特任准教授 2007 – 2009: Nagoya University, 医学部附属病院, 特任准教授 2007: 名古屋大学, 大学院・医学系研究科, COE特任准教授 2004 – 2005: 名古屋大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Science and Engineering / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Neurosurgery Except Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Tumor biology / Basic Section 37010:Bio-related chemistry / Medium-sized Section 28:Nano/micro science and related fields … More / Medium-sized Section 37:Biomolecular chemistry and related fields / Experimental pathology / Radiation science / Neurosurgery / Science and Engineering / Clinical oncology Less
Keywords	Principal Investigator 脳腫瘍 / ゲノム / エピジェネティクス / ヒストン / 創薬 / シングルセル解析 / スーパーエンハンサー / エピゲノム / ポリコーム / 悪性脳腫瘍 … More / がん / 治療 / 化合物 / 四重鎖らせん / シングルセル / CRISPR/Cas9ノックアウト / DNAバーコードラベル / 神経膠腫 / CRISPR/Cas9 / 進化トラジェクション / 遺伝子診断 / 尿遺伝子解析 / 数理モデル / エピゲノム異常 / 染色体構造異常 / マウスモデル / ポドプラニン / キメラ抗原受容体T細胞 / 細胞免疫療法 / ネオアンチゲン / エンハンサー / 分子イメージング / 神経科学 / 検診 / ナノテクノロジー / 神経再生 / 次世代シーケンス / 尿 / リキッドバイオプシー / ゲノム構造 / 癌 / 脳腫瘍学 / EZH2 / 次世代シークエンス / マウス / 遺伝子解析 / ナノメディシン / 細胞生物学 / 遺伝学 / メチル化 / エピジェネテュクス / 癌幹細胞 / 脳腫瘍の起源 / 組織培養 / 免疫療法 / 脳腫瘍幹細胞 / マイクロアレイ / パイロシークエンス / MGMT / DNAメチル化 / 診断 / 遺伝子 / インターフェロンB / インターフェロンβ / 脊髄損傷 / 分離培養 / オリゴデンドログリア / アストロサイト / ニューロン … More Except Principal Investigator 脳腫瘍 / エピジェネティクス / 分子イメージング / 脊髄損傷 / 歯髄幹細胞 / 神経再生 / Neurod4 / エピゲノム / 膠芽腫 / バイオイメージング / ヒストン修飾 / グリオブラストーマ / がん幹細胞 / イメージング / MGMT / 視床下核 / 細胞療法 / TGF-β / マクロファージ / 下肢運動機能 / MCP-1 / ヒト由来歯髄幹細胞 / 脳内移行性 / 11C標識α-ケトグルタル酸 / イソクエン酸脱水素酵素１ / 11C標識O6-ベンジルグアニン / 人工リンパ節 / 腫瘍傷害性 / T細胞 / 細胞外小胞 / 抗原提示細胞 / エクソソーム / ナノワイヤ / 脳腫瘍のエピゲノム異常 / 異常エンハンサー / EZH2 / スーパーエンハンサー異常 / エピゲノム異常 / スーパーエンハンサー / 悪性脳腫瘍 / Epigenetic alteration / Glioma mouse model / Brain tumor / 神経幹細胞 / ハイブリッドベクター / エピゲノム制御 / 脱分化 / 上位細胞 / アフリカツメガエル / 内在性神経幹細胞 / グリア瘢痕 / ウイルスベクター / 上衣細胞 / 神経転写因子 / 11C標識分子プローブ / 脳腫瘍PETイメージング / 11C標識プローブ / α-ケトグルタル酸 / 遺伝子変異イソクエン酸脱水素酵素１ / O6-ベンジルグアニン / O6-メチルグアニン-DNA-トランスフェラーゼ / EMARS / マウスモデル / グリオーマ / ガングリオシド / 1エピゲノム / ドラッグデリバリーシステム / がん治療 / がん / 非翻訳RNA / 細胞周期 / 癌遺伝子 / バイオインフォマティクス / 腫瘍生物学 / ゲノム科学 / システム生物学 / 遺伝子療法 / 免疫抑制 / 養子免疫療法 / 国際発表　アメリカ合衆国 / microRNA / 遺伝子治療 / 免疫療法 / immunotherapy / podplanin / immune modulator drugs / CAR T-Cell Therapy / micro RNA / gene therapy / immunomodulatory drug / glioblastoma / CAR / cancer immunotherapy / 遺伝子変異 / 癌治療 / 治療 / dyskinesia / single unit recording / rat / substantia nigra / neuroprotective effect / subthalamic nucleus / deep brain stimulation / Parkinson diesease / ジスキネジア / 単一神経活動記録 / ラット / 黒質 / 神経保護作用 / 深部電気刺激術 / パーキンソン病 / 薬剤送達 / 核酸療法 / 神経膠腫 / 治療予後 / 分子マーカー / 化学療法 / 薬物送達 / 分子標的薬 / PET / 創薬 / ロボティクス / ナノテクノロジー / 核酸医療 / 分子標的 / 脳神経疾患 / 反応パラメーター / 分子反応 / 化学反応パラメーター / 分子科学 / ナノマテリアル / 細胞・組織工学 / 細胞内動態 / ナノメディシン / 生物物理 / 細胞・組織 / ナノデバイス / ナノバイオ / 先端計測 / 生体材料 / 組織再生医療 / 細胞内診断 / 薬物送達システム / 細胞機能 / 細胞環境 / ナノメディシン分子科学 / ポリコーム複合体 / ポリコーム / 分子標的治療 / 臨床応用 / 有機合成 / 分子 / PETトレーサー / 分子イメーグング / 動物モデル / エピジェティクス / バイオマーカー / DNAメチル化 / マイクロアレイ / 髄膜腫 / 良性脳腫瘍 / カイニン酸 / 海馬 / 骨髄間質細胞 / 視床前核 / 視床下核学 / 脳深部刺激療法 / てんかん Less

Synthesis of functional PET probes targeting enzymes specifically expressed in glioma
- Principal Investigator
  
  古山浩子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Gifu University
The regulation of gene expression by targeting G4 quadriplex in brain tumorsPrincipal Investigator
- Principal Investigator
  
  夏目敦至
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
塩基性ヘリックスループヘリックス転写機構制御と細胞治療を融合する神経再生治療開発
- Principal Investigator
  
  西村由介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Novel PET probe for brain tumor imaging targeting specifically expressed enzymes
- Principal Investigator
  
  Suzuki Masaaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  National Center for Geriatrics and Gerontology
Creation of artificial lymph node function
- Principal Investigator
  
  Yasui Takao
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  Nagoya University
The evolutional trajection and precision-medicine to gliomasPrincipal Investigator
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury
- Principal Investigator
  
  Nishimura Yusuke
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Aberrant chromatin remodeling induced by super-enhancer formation in malignant glioma
- Principal Investigator
  
  Ohka Fumiharu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Nagoya University
Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formationPrincipal Investigator
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
Identification of molecules targeting cancers and neurons based on molecular tracingPrincipal Investigator
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Nagoya University
Super-enhancer and dynamic chromatine remodeling in gliomagenesisPrincipal Investigator
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Nagoya University
Functional analysis of gangliosides in invasion front in early stage glioma
- Principal Investigator
  
  OHKAWA Yuki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Chubu University
Identification of a novel tumor-associated protein in gliomagenesis and chemicals targeting its function.
- Principal Investigator
  
  Kondo Yutaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya City University
The development of immunotherapy in malignant brain tumor to overcome cancer immunosuppression and immune evasion
- Principal Investigator
  
  Ohno Masasuke
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  National Hospital Organization Nagoya Medical Center
Basic Research on Cancer Genes with Network Centrality
- Principal Investigator
  
  Tsutomu Mori
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Fukushima Medical University
Study of regulatory mechanism controlling cancer cell reprogramming
- Principal Investigator
  
  KONDO Yutaka
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Nagoya City University
  愛知県がんセンター(研究所)
Multimodal medical strategies by means of robotic technology according with molecular target imaging
- Principal Investigator
  
  Wakabayashi Toshihiko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
epigenetic drug development based on hierarchy and plasticity of malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  NATSUME Atsushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Nanomedicine Molecular Science
- Principal Investigator
  
  ISHIHARA KAZUHIKO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Exploration of target molecules based on genome analysis and molecular tracingPrincipal Investigator
- Principal Investigator
  
  Natsume Atsushi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Nagoya University
Epigenetic plasticity as a novel target for cancer treatment
- Principal Investigator
  
  KONDO Yutaka
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Aichi Cancer Center Research Institute
Chemical biology reprogramming epigenetic aberration in malignant brain tumorsPrincipal Investigator
- Principal Investigator
  
  NATSUME Atsushi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Development of molecular imaging tracers for anticancer drug resistant proteins
- Principal Investigator
  
  WAKABAYASHI Toshihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Identification of epigenetic biomarkers in benign brain tumors in the post-genome era
- Principal Investigator
  
  SAITO Kiyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Epigenetic Analyses of Brain Tumors for Development of Diagnosis and Treatment in the Era of PostgenomePrincipal Investigator
- Principal Investigator
  
  NATSUME Atsushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
The development of stereotactic deep brain stimulation and cell therapy for limbic seizure in rat
- Principal Investigator
  
  KAJITA Yasukazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
インターフェロンβによる中枢神経の機能再生の研究Principal Investigator
- Principal Investigator
  
  夏目敦至
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University
Development of a combination therapy of cell therapy and deep brain stimulation for Parkinson disease
- Principal Investigator
  
  KAJITA Yasukazu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Nagoya University

[Book] 最新主要文献でみる脳神経外科学レビュー2019
- Author(s)
  夏目敦至
- Total Pages
  373
- Publisher
  総合医学社
- Data Source
  KAKENHI-PLANNED-17H06356
[Book] Cancer Science2014
- Author(s)
  Kondo Y, Katsushima K, Ohka F, Natsume A, Shinjo K.
- Total Pages
  7
- Publisher
  The official journal of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-25290048
[Book] Cancer Science2014
- Author(s)
  Kondo Y, Katsushima K, Ohka F, Natsume A, Shinjo K.
- Total Pages
  7
- Publisher
  The official journal of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-26640088
[Book] NEUROLOGICAL SURGERY 脳神経外科2014
- Author(s)
  出口彰一、近藤　豊、夏目敦至
- Total Pages
  9
- Publisher
  株式会社医学書院
- Data Source
  KAKENHI-PROJECT-25290048
[Book] NEUROLOGICAL SURGERY 脳神経外科2014
- Author(s)
  出口彰一、近藤　豊、夏目敦至
- Total Pages
  9
- Publisher
  株式会社医学書院
- Data Source
  KAKENHI-PROJECT-26640088
[Book] 脳腫瘍　最新がん薬物療法学‐がん薬物療法の最新知見‐ Ⅳ臓器別がんの薬物療法2014
- Author(s)
  若林俊彦, 夏目敦至, 藤井正純
- Total Pages
  650
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-24249073
[Book] インフォームドコンセントのための図説シリーズ　脳腫瘍2013
- Author(s)
  若林俊彦、藤井正純、夏目敦至
- Total Pages
  139
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-24249073
[Book] 神経膠腫ー診断から治療までー画像診断と外科治療の融合2011
- Author(s)
  若林敏彦、夏目敦至、藤井正純
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-21390409
[Book] 化学とマイクロ・ナノシステム研究脳神経外科領域におけるマイクロナノシステムの臨床への応用2011
- Author(s)
  若林俊彦、夏目敦至、藤井正純、吉田純
- Data Source
  KAKENHI-PROJECT-21390409
[Book] 脳腫瘍取扱い規約(第3版)2010
- Author(s)
  夏目敦至
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 遺伝子診療学.脳腫瘍.ゲノム異常の最新アトラス2010
- Author(s)
  夏目敦至
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 新時代の脳腫瘍学.脳腫瘍におけるエピジェネティクス2010
- Author(s)
  夏目敦至
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 脳腫瘍-ゲノム異常の最新アトラスー.遺伝子診療学(第2版)2010
- Author(s)
  夏目敦至
- Total Pages
  150
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 脳腫瘍におけるエピジェネティクス.新時代の脳腫瘍学2010
- Author(s)
  夏目敦至
- Total Pages
  150
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 脳212009
- Author(s)
  夏目敦至
- Total Pages
  146
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-19591669
[Book] グリオーマのエピジェネティクス解析(黒岩敏彦)2009
- Author(s)
  夏目敦至
- Total Pages
  164
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-19591669
[Book] 脳腫瘍臨床病理カラーアトラス第3版2009
- Author(s)
  夏目敦至
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21390408
[Book] 看護のための最新医学講座(第2版)第1巻脳・神経系疾患2005
- Author(s)
  夏目敦至
- Total Pages
  682
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-16790816
[Journal Article] Easy-to-use machine learning system for the prediction of IDH mutation and 1p/19q codeletion using MRI images of adult-type diffuse gliomas2023
- Author(s)
  Nishikawa Tomohide、Ohka Fumiharu、Aoki Kosuke、Suzuki Hiromichi、Motomura Kazuya、Yamaguchi Junya、Maeda Sachi、Kibe Yuji、Shimizu Hiroki、Natsume Atsushi、Innan Hideki、Saito Ryuta
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 40 Issue: 2 Pages: 85-92
- DOI
  10.1007/s10014-023-00459-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19591, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-23K24449
[Journal Article] Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.2023
- Author(s)
  Das Nando D.、Chang Jen-Chien、Hon Chung-Chau、Kelly S. Thomas、Ito Shinsuke、Lizio Marina、Kaczkowski Bogumil、Watanabe Hisami、Katsushima Keisuke、Natsume Atsushi、Koseki Haruhiko、Kondo Yutaka、Minoda Aki、Umehara Takashi.
- Journal Title
  
  BMC Genomics
  
  Volume: 24 Issue: 1 Pages: 574-574
- DOI
  10.1186/s12864-023-09659-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20598, KAKENHI-PROJECT-23K05736, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-20H03388, KAKENHI-PROJECT-23K27438
[Journal Article] Prediction of Tumor Development and Urine-Based Liquid Biopsy for Molecule-Targeted Therapy of Gliomas2023
- Author(s)
  Kurimoto Michihiro、Rockenbach Yumi、Kato Akira、Natsume Atsushi
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 6 Pages: 1201-1201
- DOI
  10.3390/genes14061201
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03789
[Journal Article] All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an <i>ex Vivo</i> Brain Tumor Model2023
- Author(s)
  Chattrairat Kunanon、Yasui Takao、Suzuki Shunsuke、Natsume Atsushi、Nagashima Kazuki、Iida Mikiko、Zhang Min、Shimada Taisuke、Kato Akira、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 3 Pages: 2235-2244
- DOI
  10.1021/acsnano.2c08526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05778, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-21H01968
[Journal Article] Mutation detection of urinary cell-free DNA via catch-and-release isolation on nanowires for liquid biopsy2023
- Author(s)
  Takahashi Hiromi、Yasui Takao、Hirano Masaki、Shinjo Keiko、Miyazaki Yusuke、Shinoda Wataru、Hasegawa Takeshi、Natsume Atsushi、Kitano Yotaro、Ida Mikiko、Zhang Min、Shimada Taisuke、Paisrisarn Piyawan、Zhu Zetao、Ohka Fumiharu、Aoki Kosuke、Rahong Sakon、Nagashima Kazuki、Yanagida Takeshi、Baba Yoshinobu
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 234 Pages: 115318-115318
- DOI
  10.1016/j.bios.2023.115318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0209, KAKENHI-PROJECT-19K07661, KAKENHI-PROJECT-23K06633, KAKENHI-PROJECT-21K18979, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-21H01968
[Journal Article] Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas2023
- Author(s)
  Bredel Markus、Espinosa Llus、Kim Hyunsoo、Scholtens Denise M.、McElroy Joseph P.、Rajbhandari Rajani、Meng Wei、Kollmeyer Thomas M.、Malta Tathiane M.、Quezada Michael A.、Natsume Atsushi、Ogawa Seishi、Weber Ruthild G.、Pugh Stephanie L.、Chakravarti Arnab
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 6 Pages: 101082-101082
- DOI
  10.1016/j.xcrm.2023.101082
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03789
[Journal Article] Efficacy of cancer-specific anti-podoplanin CAR-T cells and oncolytic herpes virus G47Δ combination therapy against glioblastoma2022
- Author(s)
  Chalise Lushun、Kato Akira、Ohno Masasuke、Maeda Sachi、Yamamichi Akane、Kuramitsu Shunichiro、Shiina Satoshi、Takahashi Hiromi、Ozone Sachiko、Yamaguchi Junya、Kato Yukinari、Rockenbach Yumi、Natsume Atsushi、Todo Tomoki
- Journal Title
  
  Molecular Therapy - Oncolytics
  
  Volume: 26 Pages: 265-274
- DOI
  10.1016/j.omto.2022.07.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09223, KAKENHI-PROJECT-22H00483, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356
[Journal Article] Electron-transfer kinetics through nucleic acids untangled by single-molecular fluorescence blinking2022
- Author(s)
  Fan Shuya、Xu Jie、Osakada Yasuko、Hashimoto Katsunori、Takayama Kazuya、Natsume Atsushi、Hirano Masaki、Maruyama Atsushi、Fujitsuka Mamoru、Kawai Kumi、Kawai Kiyohiko
- Journal Title
  
  Chem
  
  Volume: 8 Issue: 11 Pages: 3109-3119
- DOI
  10.1016/j.chempr.2022.07.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02059, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356
[Journal Article] The first-in-human phase I study of a brain-penetrant mutant IDH1 inhibitor DS-1001 in patients with recurrent or progressive IDH1-mutant gliomas2022
- Author(s)
  Natsume Atsushi、et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 25 Issue: 2 Pages: 326-336
- DOI
  10.1093/neuonc/noac155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-20H03789, KAKENHI-PLANNED-17H06356
[Journal Article] Importance of Hydrostatic Pressure and Irrigation for Hemostasis in Neuroendoscopic Surgery2021
- Author(s)
  ISHIKAWA Takayuki、TAKEUCHI Kazuhito、YAMAMOTO Taiki、NAGATA Yuichi、NATSUME Atsushi
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 61 Issue: 2 Pages: 117-123
- DOI
  10.2176/nmc.oa.2020-0278
- NAID
  130007986449
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356
[Journal Article] Annealed ZnO/Al2O3 Core-Shell Nanowire as a Platform to Capture RNA in Blood Plasma2021
- Author(s)
  Takahashi Hiromi、Yasui Takao、Klamchuen Annop、Khemasiri Narathon、Wuthikhun Tuksadon、Paisrisarn Piyawan、Shinjo Keiko、Kitano Yotaro、Aoki Kosuke、Natsume Atsushi、Rahong Sakon、Baba Yoshinobu
- Journal Title
  
  Nanomaterials
  
  Volume: 11 Issue: 7 Pages: 1768-1768
- DOI
  10.3390/nano11071768
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21124, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-21H01960, KAKENHI-PROJECT-20J15564
[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021
- Author(s)
  Aoki K, Suzuki H, Yamamoto T, Yamamoto KN, Maeda S, Okuno Y, Ranjit M, Kitano Y, Yamaguchi J, Yamazaki S, Nakamura H, Takahashi M, Narita Y, Nakada M, Deguchi S, Mizoguchi M, Momii Y, Muragaki Y, Abe T, Akimoto J, Wakabayashi T, Saito R, Ogawa S, Haeno H, Natsume A.
- Journal Title
  
  Cancer Res.
  
  Volume: 81 Pages: 4861-4873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] Preoperative Intracranial Dissemination of Spinal Myxopapillary Ependymoma Attributed to Tumor Hemorrhage2021
- Author(s)
  Awaya Takayuki、Nishimura Yusuke、Eguchi Kaoru、Nagashima Yoshitaka、Ando Ryo、Akahori Sho、Yoshikawa Satoshi、Haimoto Shoichi、Hara Masahito、Natsume Atsushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 145 Pages: 13-18
- DOI
  10.1016/j.wneu.2020.08.169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09453
[Journal Article] Effects of aspirin and heparin treatment on perioperative outcomes in patients with Moyamoya disease.2021
- Author(s)
  3.Kanamori F, Araki Y, Yokoyama K, Uda K, Mamiya T, Nishihori M, Izumi T, Okamoto S, Natsume A.
- Journal Title
  
  Acta Neurochir (Wien)
  
  Volume: 163 Issue: 5 Pages: 1485-91
- DOI
  10.1007/s00701-020-04668-0
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] Urinary MicroRNA-Based Diagnostic Model for Central Nervous System Tumors Using Nanowire Scaffolds2021
- Author(s)
  Kitano Yotaro、Aoki Kosuke、Ohka Fumiharu、Yamazaki Shintaro、Motomura Kazuya、Tanahashi Kuniaki、Hirano Masaki、Naganawa Tsuyoshi、Iida Mikiko、Shiraki Yukihiro、Nishikawa Tomohide、Shimizu Hiroyuki、Yamaguchi Junya、Maeda Sachi、Suzuki Hidenori、Wakabayashi Toshihiko、Baba Yoshinobu、Yasui Takao、Natsume Atsushi
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 15 Pages: 17316-17329
- DOI
  10.1021/acsami.1c01754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21124, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19KK0228
[Journal Article] Effects of insular resection on interactions between cardiac interoception and emotion recognition.2021
- Author(s)
  2.Terasawa Y, Motomura K, Natsume A, Iijima K, Chalise L, Sugiura J, Yamamoto H, Koyama K, Wakabayashi T, Umeda S.
- Journal Title
  
  Cortex
  
  Volume: 137 Pages: 271-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] Newly established patient-derived organoid model of intracranial meningioma2021
- Author(s)
  Yamazaki Shintaro、Ohka Fumiharu、Hirano Masaki、Shiraki Yukihiro、Motomura Kazuya et al
- Journal Title
  
  Neuro-Oncology
  
  Volume: 23 Issue: 11 Pages: 1936-1948
- DOI
  10.1093/neuonc/noab155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-21K16645, KAKENHI-PROJECT-20H03789, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-20H03511, KAKENHI-PROJECT-20J01889, KAKENHI-PROJECT-20K20598
[Journal Article] Spontaneous Rupture of a Huge Presacral Tarlov Cyst Leading to Dramatic Neurologic Recovery2021
- Author(s)
  Akahori Sho、Nishimura Yusuke、Eguchi Kaoru、Nagashima Yoshitaka、Ando Ryo、Awaya Takayuki、Hara Masahito、Natsume Atsushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 145 Pages: 306-310
- DOI
  10.1016/j.wneu.2020.09.098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09453
[Journal Article] Mathematical Modeling and Mutational Analysis Reveal Optimal Therapy to Prevent Malignant Transformation in Grade II IDH-Mutant Gliomas.2021
- Author(s)
  Aoki K, Suzuki H, Yamamoto T, Yamamoto KN, Yamazaki S, Nakamura H, Takahashi M, Narita Y, Nakada M, Deguchi S, Mizoguchi M, Momii Y, Muragaki Y, Abe T, Akimoto J, Wakabayashi T, Saito R, Ogawa S, Haeno H, Natsume A.
- Journal Title
  
  Cancer Res.
  
  Volume: 81 Pages: 4861-4873
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03789
[Journal Article] So-called bifocal tumors with diabetes insipidus and negative tumor markers: are they all germinoma?2021
- Author(s)
  Kanamori M, Takami H, Kijima N, Terashima K, Ichimura K, Nishikawa R, et al,
- Journal Title
  
  Neuro-Oncology
  
  Volume: 23 Issue: 2 Pages: 295-303
- DOI
  10.1093/neuonc/noaa199
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08345, KAKENHI-PROJECT-18K08970, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18K15687
[Journal Article] Ependymoma-like tumor with mesenchymal differentiation harboring C11orf95-NCOA1/2 or -RELA fusion: A hitherto unclassified tumor related to ependymoma2021
- Author(s)
  Tomomasa R, Arai Y, Kawabata-Iwakawa R, Fukuoka K, Nakano Y, Hama N, Nakata S, Suzuki N, Ishi Y, Tanaka S, Takahashi JA, Yuba Y, Shiota M, Natsume A, Kurimoto M, Shiba Y, Aoki M, Nabeshima K, Enomoto T, Inoue T, Fujimura J, Kondo A, Yao T, Okura N, Hirose T, Sasaki A, Hirato J, Yokoo H, Nobusawa S.
- Journal Title
  
  Brain Pathol .
  
  Volume: 1 Issue: 3 Pages: 1-9
- DOI
  10.1111/bpa.12943
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-19K16579, KAKENHI-PROJECT-19K07411, KAKENHI-PROJECT-21K07110
[Journal Article] Neurod4 converts endogenous neural stem cells to neurons with synaptic formation after spinal cord injury2021
- Author(s)
  Fukuoka Toshiki、Kato Akira、Hirano Masaki、Ohka Fumiharu、Aoki Kosuke、Awaya Takayuki、Adilijiang Alimu、Sachi Maeda、Tanahashi Kuniaki、Yamaguchi Junya、Motomura Kazuya、Shimizu Hiroyuki、Nagashima Yoshitaka、Ando Ryo、Wakabayashi Toshihiko、Lee-Liu Dasfne、Larrain Juan、Nishimura Yusuke、Natsume Atsushi
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 2 Pages: 102074-102074
- DOI
  10.1016/j.isci.2021.102074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-19K09453
[Journal Article] Multiple metastases to the bone and bone marrow from a 1p/19q-codeleted and IDH2-mutant anaplastic oligodendroglioma: a case report and literature review2020
- Author(s)
  Shimizu Hiroyuki、Motomura Kazuya、Ohka Fumiharu、Aoki Kosuke、Tanahashi Kuniaki、Hirano Masaki、Chalise Lushun、Nishikawa Tomohide、Yamaguchi Junya、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  Neuro-Oncology Advances
  
  Volume: 2 Issue: 1 Pages: 1-9
- DOI
  10.1093/noajnl/vdaa101
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-18H02911, KAKENHI-PLANNED-17H06356
[Journal Article] Long-term survival in patients with primary intracranial germ cell tumors treated with surgery, platinum-based chemotherapy, and radiotherapy: a single-institution study2020
- Author(s)
  Shimizu Hiroyuki、Motomura Kazuya、Ohka Fumiharu、Aoki Kosuke、Tanahashi Kuniaki、Hirano Masaki、Chalise Lushun、Nishikawa Tomohide、Yamaguchi Junya、Yoshida Jun、Natsume Atsushi、Wakabayashi Toshihiko
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: － Issue: 2 Pages: 1-9
- DOI
  10.3171/2020.6.jns20638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-18H02911, KAKENHI-PLANNED-17H06356
[Journal Article] H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant.2020
- Author(s)
  Maeda S, Ohka F, Okuno Y, Aoki K, Motomura K, Takeuchi K, Kusakari H, Yanagisawa N, Sato S, Yamaguchi J, Tanahashi K, Hirano M, Kato A, Shimizu H, Kitano Y, Yamazaki S, Yamashita S, Takeshima H, Shinjo K, Kondo Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 8 Issue: 1 Pages: 8-19
- DOI
  10.1186/s40478-020-0882-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09478, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-17K17792, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K20598
[Journal Article] Preoperative predictive factors affecting return to work in patients with gliomas undergoing awake brain mapping.2020
- Author(s)
  Yoshida A, Motomura K, Natsume A, Chalise L, Iijima K, Hara D, Kadono I, Wakai K, Wakabayashi T.
- Journal Title
  
  J Neurooncol.
  
  Volume: 146(1) Issue: 1 Pages: 195-205
- DOI
  10.1007/s11060-019-03371-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-18H02911
[Journal Article] Trautmann-focused mastoidectomy for a simple, safe presigmoid approach: technical note.2020
- Author(s)
  Tanahashi K, Uda K, Araki Y, Takeuchi K, Choo J, Chalise L, Motomura K, Ohka F, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 3 Issue: 3 Pages: 1-5
- DOI
  10.3171/2020.1.jns193179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-17K16639, KAKENHI-PROJECT-17K10862
[Journal Article] Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2)2020
- Author(s)
  Naito Y, Aburatani H, Amano T, Baba E, Furukawa T, Hayashida T, Hiyama E, Ikeda S, Kanai M, Kato M, Kinoshita I, Kiyota N, Kohno T, Kohsaka S, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: － Issue: 2 Pages: 233-283
- DOI
  10.1007/s10147-020-01831-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02677, KAKENHI-PROJECT-18K09249, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-19H01056
[Journal Article] Surgical outcome and graded prognostic assessment of patients with brain metastasis from adult sarcoma: multi-institutional retrospective study in Japan2020
- Author(s)
  Shoichi Deguchi, Yoko Nakasu, Tsukasa Sakaida, Jiro Akimoto, Kuniaki Tanahashi, Atsushi Natsume, Masamichi Takahashi, Takeshi Okuda, Hirofumi Asakura, Koichi Mitsuya, Nakamasa Hayashi, Yoshitaka Narita
- Journal Title
  
  International journal of clinical oncology
  
  Volume: 25 Issue: 11 Pages: 1995-2005
- DOI
  10.1007/s10147-020-01740-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09378, KAKENHI-PLANNED-17H06356
[Journal Article] Complete resection and untethering of the cervical and thoracic spinal dermal sinus tracts in adult patients2020
- Author(s)
  Nishimura Y, Hara M, Natsume A, Wakabayashi T, Ginsberg HJ
- Journal Title
  
  Nagoya Journal of Medical Science
  
  Volume: 82 Issue: 3 Pages: 567-577
- DOI
  10.18999/nagjms.82.3.567
- NAID
  120006881557
- ISSN
  2186-3326
- URL
  https://nagoya.repo.nii.ac.jp/records/30426
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09453
[Journal Article] Navigated repetitive transcranial magnetic stimulation as preoperative assessment in patients with brain tumors2020
- Author(s)
  Motomura Kazuya、Takeuchi Hiroki、Nojima Ippei、Aoki Kosuke、Chalise Lushun、Iijima Kentaro、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 1-1
- DOI
  10.1038/s41598-020-65944-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-20K09448, KAKENHI-PROJECT-19K22804, KAKENHI-PROJECT-19KK0228, KAKENHI-PROJECT-18H02911, KAKENHI-PROJECT-17H04748, KAKENHI-PROJECT-19H01091
[Journal Article] Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas2019
- Author(s)
  Ohka Fumiharu、Shinjo Keiko、Deguchi Shoichi、Matsui Yusuke et al.
- Journal Title
  
  Cancer Research
  
  Volume: 79 Issue: 19 Pages: 4814-4827
- DOI
  10.1158/0008-5472.can-19-1272
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18151, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04899, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-17H03582, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-17K07247
[Journal Article] Anterior insular cortex stimulation and its effects on emotion recognition.2019
- Author(s)
  Motomura K, Terasawa Y, Natsume A, Iijima K, Chalise L, Sugiura J, Yamamoto H, Koyama K, Wakabayashi T, Umeda S.
- Journal Title
  
  Brain Struct Funct.
  
  Volume: 224(6) Issue: 6 Pages: 2167-2181
- DOI
  10.1007/s00429-019-01895-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19K21819, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02911
[Journal Article] Spontaneous Tumor Regression of Intracranial Solitary Fibrous Tumor Originating From the Medulla Oblongata: A Case Report and Literature Review.2019
- Author(s)
  Yamaguchi J, Motomura K, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Shimizu H, Wakabayashi T, Natsume A.
- Journal Title
  
  World Neurosurg
  
  Volume: 130 Pages: 400-404
- DOI
  10.1016/j.wneu.2019.07.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06356
[Journal Article] Multiplex ligation-dependent probe amplification analysis is useful for detecting a copy number gain of the FGFR1 tyrosine kinase domain in dysembryoplastic neuroepithelial tumors.2019
- Author(s)
  Matsumura N, Nobusawa S, Ito J, Kakita A, Suzuki H, Fujii Y, Fukuda M, Iwasaki M, Nakasato N, Tominaga T, Natsume A, Mikami Y, Shinojima N, Yamazaki T, Nakazato Y, Hirato J, Yokoo H.
- Journal Title
  
  J Neurooncol.
  
  Volume: 143 Issue: 1 Pages: 27-33
- DOI
  10.1007/s11060-019-03138-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10888, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-19H01061
[Journal Article] Neurocognitive and functional outcomes in patients with diffuse frontal lower-grade gliomas undergoing intraoperative awake brain mapping.2019
- Author(s)
  Motomura K, Chalise L, Ohka F, Aoki K, Tanahashi K, Hirano M, Nishikawa T, Yamaguchi J, Shimizu H, Wakabayashi T, Natsume A.
- Journal Title
  
  J Neurosurg.
  
  Volume: 17 Issue: 6 Pages: 1-9
- DOI
  10.3171/2019.3.jns19211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-19KK0228, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02911
[Journal Article] Aberrant Transcriptional Regulation of Super-enhancers by RET Finger Protein-histone Deacetylase 1 Complex in Glioblastoma: Chemoresistance to Temozolomide2019
- Author(s)
  NATSUME Atsushi、HIRANO Masaki、RANJIT Melissa、AOKI Kosuke、WAKABAYASHI Toshihiko
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 59 Issue: 8 Pages: 293-298
- DOI
  10.2176/nmc.ra.2019-0049
- NAID
  130007690186
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0228
[Journal Article] Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma.2019
- Author(s)
  Adilijiang A, Hirano M, Okuno Y, Aoki K, Ohka F, Maeda S, Tanahashi K, Motomura K, Shimizu H, Yamaguchi J, Wakabayashi T, Natsume A.
- Journal Title
  
  Molecules
  
  Volume: 24(17) Issue: 17 Pages: 3046-3046
- DOI
  10.3390/molecules24173046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06356
[Journal Article] Posterior Cerebral Artery Reconstruction by In-Situ Bypass with Superior Cerebellar Artery via Occipital Transtentorial Approach2019
- Author(s)
  Tanahashi Kuniaki、Araki Yoshio、Uda Kenji、Muraoka Shinsuke、Motomura Kazuya、Lushun Chalise、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 126 Pages: 24-29
- DOI
  10.1016/j.wneu.2019.02.127
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-19KK0228
[Journal Article] Novel Human NK Cell Line Carrying CAR Targeting EGFRvIII Induces Antitumor Effects in Glioblastoma Cells.2018
- Author(s)
  Murakami T, Nakazawa T(equally contribution), Natsume A, Nishimura F, Nakamura M, Matsuda R, Omoto K, Tanaka Y, Shida Y, Park YS, Motoyama Y, Nakagawa I, Yamada S, Tamura K, Takeshima Y, Takamura Y,
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Issue: 9 Pages: 5049-5056
- DOI
  10.21873/anticanres.12824
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16567, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-18H02915, KAKENHI-PROJECT-16K10767, KAKENHI-PROJECT-16K10768
[Journal Article] Validation of a novel molecular RPA classification in glioblastoma (GBM-molRPA) treated with chemoradiation: A multi-institutional collaborative study.2018
- Author(s)
  Wee CW, Kim IH, Park CK, Kim JW, Dho YS, Ohka F, Aoki K, Motomura K, Natsume A, Kim N, Suh CO, Chang JH, Kim SH, Cho WK, Lim DH, Nam DH, Choi JW, Kim IA, Kim CY, Oh YT, Cho O, Chung WK, Kim SH, Kim E.
- Journal Title
  
  Radiother Oncol.
  
  Volume: 129(2) Issue: 2 Pages: 347-351
- DOI
  10.1016/j.radonc.2018.09.001
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-17H06356
[Journal Article] Podoplanin - an emerging cancer biomarker and therapeutic target.2018
- Author(s)
  Krishnan H, Rayes J, Miyashita T, Ishii G, Retzbach EP, Sheehan SA, Takemoto A, Chang YW, Yoneda K, Asai J, Jensen L, Chalise L, Natsume A, Goldberg GS.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中 Issue: 5 Pages: 1292-1299
- DOI
  10.1111/cas.13580
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-18K07216, KAKENHI-PROJECT-16H01747
[Journal Article] A randomized, double-blind, phase III trial of personalized peptide vaccination for recurrent glioblastoma.2018
- Author(s)
  Narita Y, Arakawa Y, Yamasaki F, Nishikawa R, Aoki T, Kanamori M, Nagane M, Kumabe T, Hirose Y, Ichikawa T, Kobayashi H, Fujimaki T, Goto H, Takeshima H, Ueba T, Abe H, Tamiya T, Sonoda Y, Natsume A, Kakuma T, Sugita Y, Komatsu N, Yamada A, Sasada T, Matsueda S, Shichijo S, Itoh K, Terasaki M.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 21 Issue: 3 Pages: 348-359
- DOI
  10.1093/neuonc/noy200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10867, KAKENHI-PROJECT-18K19490, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17H04278, KAKENHI-PROJECT-16K10754, KAKENHI-PROJECT-16K10757, KAKENHI-PROJECT-18K09004
[Journal Article] A novel high-sensitivity assay to detect a small fraction of mutant IDH1 using droplet digital PCR2018
- Author(s)
  Hirano Masaki、Ohka Fumiharu、Maeda Sachi、Chalise Lushun、Yamamichi Akane、Aoki Kosuke、Kato Akira、Tanahashi Kuniaki、Motomura Kazuya、Nishimura Yusuke、Hara Masahito、Shinjo Keiko、Kondo Yutaka、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: - Issue: 2 Pages: 97-105
- DOI
  10.1007/s10014-018-0310-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16643, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17H03582, KAKENHI-PLANNED-17H06356
[Journal Article] Immunohistochemical ATRX expression is not a surrogate for 1p19q codeletion2018
- Author(s)
  Yamamichi Akane、Ohka Fumiharu、Aoki Kosuke、Suzuki Hiromichi、Kato Akira、Hirano Masaki、Motomura Kazuya、Tanahashi Kuniaki、Chalise Lushun、Maeda Sachi、Wakabayashi Toshihiko、Kato Yukinari、Natsume Atsushi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: - Issue: 2 Pages: 106-113
- DOI
  10.1007/s10014-018-0312-5
- NAID
  120006496406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-16K10748
[Journal Article] Supratotal Resection of Diffuse Frontal Lower Grade Gliomas with Awake Brain Mapping, Preserving Motor, Language, and Neurocognitive Functions2018
- Author(s)
  Motomura Kazuya、Chalise Lushun、Ohka Fumiharu、Aoki Kosuke、Tanahashi Kuniaki、Hirano Masaki、Nishikawa Tomohide、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 119 Pages: 30-39
- DOI
  10.1016/j.wneu.2018.07.193
- NAID
  120006554487
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356
[Journal Article] Characterization of Intraoperative Motor Evoked Potential Monitoring for Surgery of the Pediatric Population with Brain Tumors2018
- Author(s)
  Motomura Kazuya、Sumita Kayo、Chalise Lushun、Nishikawa Tomohide、Tanahashi Kuniaki、Ohka Fumiharu、Aoki Kosuke、Hirano Masaki、Nakamura Tomohiko、Matsushita Tadashi、Wakabayashi Toshihiko、Natsume Atsushi
- Journal Title
  
  World Neurosurgery
  
  Volume: 119 Pages: e1052-e1059
- DOI
  10.1016/j.wneu.2018.08.039
- NAID
  120006554488
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356
[Journal Article] Neuro-endoscopic cylinder surgery and 5-aminolevulinic acid (5-ALA) photodynamic diagnosis of deep-seated intracranial lesions.2018
- Author(s)
  Choo J, Takeuchi K, Nagata Y, Ohka F, Kishida Y, Watanabe T, Satoh Y, Nagatani T, Kato K, Wakabayashi T, Natsume A.
- Journal Title
  
  World Neurosurg.
  
  Volume: 印刷中 Pages: e35-e41
- DOI
  10.1016/j.wneu.2018.03.112
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436
[Journal Article] Cytokine Therapy of Gliomas2018
- Author(s)
  Iwami Kenichiro、Natsume Atsushi、Wakabayashi Toshihiko
- Journal Title
  
  Prog Neurol Surg
  
  Volume: ー Pages: 79-89
- DOI
  10.1159/000469682
- ISBN
  9783318060621, 9783318060638
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356
[Journal Article] Inflammation Flare and Radiation Necrosis Around a Stereotactic Radiotherapy-Pretreated Brain Metastasis Site After Nivolumab Treatment2018
- Author(s)
  Furuta Hiromi、Yoshida Tatsuya、Natsume Atsushi、Hida Toyoaki、Yatabe Yasushi
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 13 Issue: 12 Pages: 1975-1978
- DOI
  10.1016/j.jtho.2018.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356
[Journal Article] Pediatric-type follicular lymphoma in the dura: a case report and literature review.2018
- Author(s)
  Yamaguchi J, Kato S, Iwata E, Aoki K, Kabeya R, Natsume A, Wakabayashi T.
- Journal Title
  
  World Neurosurg.
  
  Volume: 印刷中 Pages: 176-180
- DOI
  10.1016/j.wneu.2018.04.053
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436
[Journal Article] Prognostic relevance of genetic alterations in diffuse lower-grade gliomas2017
- Author(s)
  Aoki Kosuke、Nakamura Hideo、Suzuki Hiromichi et al.
- Journal Title
  
  Neuro-Oncology
  
  Volume: 20 Issue: 1 Pages: 66-77
- DOI
  10.1093/neuonc/nox132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10761, KAKENHI-PROJECT-17K16643, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-17H00758, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-17K10862, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-15H05325
[Journal Article] Development of Database and Genomic Medicine for von Hippel-Lindau Disease in Japan2017
- Author(s)
  Takayanagi S, Mukasa A, Nakatomi H, Kanno H, Kuratsu JI, Nishikawa R, Mishima K, Natsume A, Wakabayashi T, Houkin K, Terasaka S, Yao M, Shinohara N, Shuin T, Saito N.
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 57 Issue: 2 Pages: 59-65
- DOI
  10.2176/nmc.ra.2016-0206
- NAID
  130005394576
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-26670636, KAKENHI-PROJECT-15K10366, KAKENHI-PROJECT-15K19950
[Journal Article] Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis2017
- Author(s)
  Deguchi S、Katsushima K、Hatanaka A、Shinjo K、Ohka F、Wakabayashi T、Zong H、Natsume A、Kondo Y
- Journal Title
  
  Oncogene
  
  Volume: 36 Issue: 32 Pages: 4629-4640
- DOI
  10.1038/onc.2017.88
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14995, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-17H03582
[Journal Article] Oncogenic effects of evolutionarily conserved noncoding RNA ECONEXIN on gliomagenesis.2017
- Author(s)
  Deguchi S, Katsushima K, Hatanaka A, Shinjo K, Ohka F, Wakabayashi T, Zong H, Natsume A, Kondo Y.
- Journal Title
  
  Oncogene.
  
  Volume: 印刷中 Issue: 1
- DOI
  10.1186/s12934-017-0682-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05436
[Journal Article] Synthesis of PET probe O6-[(3-[11C]methyl)benzyl]guanine by Pd0-mediated rapid C-[11C]methylation toward imaging DNA repair protein O6-methylguanine-DNA methyltransferase in glioblastoma.2017
- Author(s)
  Koyama H, Ikenuma H, Toda H, Kondo G, Hirano M, Kato M, Abe J, Yamada T, Wakabayashi T, Ito K, Natsume A, Suzuki M.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 27 Issue: 9 Pages: 1892-1896
- DOI
  10.1016/j.bmcl.2017.03.045
- NAID
  120006331834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-16K20004
[Journal Article] A novel all-in-one intraoperative genotyping system for IDH1-mutant glioma.2017
- Author(s)
  Ohka F, Yamamichi A, Kurimoto M, Motomura K, Tanahashi K, Suzuki H, Aoki K, Deguchi S, Chalise L, Hirano M, Kato A, Nishimura Y, Hara M, Kato Y, Wakabayashi T, Natsume A.
- Journal Title
  
  Brain Tumor Pathol.
  
  Volume: 印刷中 Issue: 2 Pages: 91-97
- DOI
  10.1007/s10014-017-0281-0
- NAID
  120006331835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-16K10748, KAKENHI-PROJECT-17K10862, KAKENHI-PROJECT-17K16643
[Journal Article] Surgical benefits of combined awake craniotomy and intraoperative magnetic resonance imaging for gliomas associated with eloquent areas.2017
- Author(s)
  Motomura K, Natsume A, Iijima K, Kuramitsu S, Fujii M, Yamamoto T, Maesawa S, Sugiura J, Wakabayashi T.
- Journal Title
  
  J Neurosurg.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05436
[Journal Article] Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack2017
- Author(s)
  Yoshida Y, Wang H, Hiwasa T, Machida T, Takiguchi M, Iwadate Y, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 3 Pages: 8836-8848
- DOI
  10.1007/s11060-018-2831-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10750, KAKENHI-PROJECT-16K10757, KAKENHI-PLANNED-17H06356, KAKENHI-PROJECT-16H05436, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-15K10343, KAKENHI-PROJECT-15K10346, KAKENHI-PROJECT-18K08998, KAKENHI-PROJECT-16K10754, KAKENHI-PROJECT-17H04300, KAKENHI-PROJECT-26293321
[Journal Article] CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains2016
- Author(s)
  Shiina S, Ohno M, Ohka F, Kuramitsu S, Yamamichi A, Kato A, Motomura K, Tanahashi K, Yamamoto T, Watanabe R, Ito I, Senga T, Hamaguchi M, Wakabayashi T, Kaneko MK, Kato Y, Chandramohan V, Bigner DD, Natsume A
- Journal Title
  
  Cancer immunology research
  
  Volume: 4 Issue: 3 Pages: 259-268
- DOI
  10.1158/2326-6066.cir-15-0060
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861270
[Journal Article] Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment.2016
- Author(s)
  Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, Sato S, Takahashi S, Kimura H, Totoki Y, Shibata T, Naito M, Kim HJ, Miyata K, Kataoka K, Kondo Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 7 Issue: 1 Pages: 13616-13616
- DOI
  10.1038/ncomms13616
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290048, KAKENHI-PROJECT-26430136, KAKENHI-PROJECT-25000006, KAKENHI-PROJECT-25282141
[Journal Article] Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses2015
- Author(s)
  Kuramitsu S, Ohno M, Ohka F, Shiina S, Yamamichi A, Kato A, Tanahashi K, Motomura K, Kondo G, Kurimoto M, Senga T, Wakabayashi T, Natsume A
- Journal Title
  
  Cancer Gene Therpy
  
  Volume: 22 Issue: 10 Pages: 487-495
- DOI
  10.1038/cgt.2015.47
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861270
[Journal Article] Paired related homeobox 1 is associated with the invasive properties of glioblastoma cells.2015
- Author(s)
  Sugiyama M, Hasegawa H, Ito S, Sugiyama K, Maeda M, Aoki K, Wakabayashi T, Hamaguchi M, Natsume A, Senga T.
- Journal Title
  
  Oncol Rep.
  
  Volume: 33 Issue: 3 Pages: 1123-30
- DOI
  10.3892/or.2014.3681
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24390341, KAKENHI-PROJECT-25861269
[Journal Article] Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses.2015
- Author(s)
  Kuramitsu S, Ohno M, Ohka F, Shiina S, Yamamichi A, Kato A, Tanahashi K, Motomura K, Kondo G, Kurimoto M, Senga T, Wakabayashi T, Natsume A
- Journal Title
  
  Cancer Gene Ther,
  
  Volume: 22 Pages: 487-95
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Mutational landscape and clonal architecture in grade II and III gliomas2015
- Author(s)
  Suzuki H, Aoki K, Natsume A, Ogawa S. et al.
- Journal Title
  
  Nat Genet.
  
  Volume: 47 Issue: 5 Pages: 458-468
- DOI
  10.1038/ng.3273
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22134006, KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24390341, KAKENHI-PROJECT-15K10337, KAKENHI-PROJECT-15K12139, KAKENHI-PROJECT-15K19964, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26640088, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25861268, KAKENHI-PROJECT-25290048
[Journal Article] Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase.2015
- Author(s)
  Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Kotani N, Honke K, Suzumura A, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 26 Pages: 16043-16058
- DOI
  10.1074/jbc.m114.635755
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460404, KAKENHI-PROJECT-15K19073, KAKENHI-PLANNED-23110008, KAKENHI-PROJECT-24590478, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-26860321, KAKENHI-PROJECT-24390078
[Journal Article] Mutational landscape and clonal architecture in grade II and III gliomas.2015
- Author(s)
  Suzuki H, Aoki K,Niida A, Motomura K, Ohka F, Yamamoto T, Tanahashi K, Ranjit M,Wakabayashi T, Yoshizato T, Kataoka K, Yoshida K, Nagata Y, Sato-Otsubo A, Tanaka H, Sanada M, Kondo Y, Nakamura H, Mizoguchi M, Abe T, Muragaki Y, Watanabe R, Ito I, Miyano S, Natsume A, Ogawa S
- Journal Title
  
  Nat Genet
  
  Volume: 47 Pages: 458-68
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Effectiveness of plasma treatment on gastric cancer cells.2015
- Author(s)
  Torii K, Yamada S, Nakamura K, Tanaka H, Kajiyama H, Tanahashi K, Iwata N, Kanda M, Kobayashi D, Tanaka C, Fujii T, Nakayama G, Koike M, Sugimoto H, Nomoto S, Natsume A, Fujiwara M, Mizuno M, Hori M, Saya H, Kodera Y
- Journal Title
  
  Gastric Cancer
  
  Volume: 20 Pages: 100-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Peptide-based inhibition of the HOXA9/PBX interaction retards the growth of human meningioma2014
- Author(s)
  Ando H, Natsume A, Senga T, Watanabe R, Ito I, Ohno M, Iwami K, Ohka F, Motomura K, Saito K, Morgan R, Wakabayashi T
- Journal Title
  
  Cancer Chemother. Pharmacol.
  
  Volume: 73(1) Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Preclinical evaluation of an O(6)-methylguanine-DNA methyltransferase-siRNA/liposome complex administered by convection-enhanced delivery to rat and porcine brains.2014
- Author(s)
  Tsujiuchi T, Natsume A, Motomura K, Kondo G, Ranjit M, Hachisu R, Sugimura I, Tomita S, Takehara I, Woolley M, Barua NU, Gill SS, Bienemann AS, Yamashita Y, Toyokuni S, Wakabayashi T.
- Journal Title
  
  Am J Transl Res.
  
  Volume: 15 Pages: 169-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy2014
- Author(s)
  Tanahashi K, Natsume A, Ohka F, Momota H, Kato A, Motomura K, Watabe N, Muraishi S, Nakahara H, Saito Y, Takeuchi I, Wakabayashi T
- Journal Title
  
  Biomed Res Int
  
  Volume: 1 Pages: 860241-860241
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Epigenetic dysregulation in glioma.2014
- Author(s)
  Kondo Y, Katsushima K, Ohka F, Natsume A, Shinjo K
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Pages: 363-9
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Association of dorsal inferior frontooccipital fasciculus fibers in the deep parietal lobe with both reading and writing processes: a brain mapping study.2014
- Author(s)
  Motomura K, Fujii M, Maesawa S, Kuramitsu S, Natsume A, Wakabayashi T.
- Journal Title
  
  J Neurosurg.
  
  Volume: 1 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Peptide-based inhibition of the HOXA9/PBX interaction retards the growth of human meningioma2014
- Author(s)
  Ando H, Natsume A, Senga T, Watanabe R, Ito I, Ohno M, Iwami K, Ohka F, Motomura K, Saito K, Morgan R, Wakabayashi T
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 73 Pages: 53-60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Association of dorsal inferior frontooccipital fasciculus fibers in the deep parietal lobe with both reading and writing processes,a brain mapping study2014
- Author(s)
  Motomura K, Fujii M,Maesawa S,Kuramitsu S,Natsume A,Wakabayashi T
- Journal Title
  
  J Neurosurg
  
  Volume: 121(1) Pages: 142-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation.2014
- Author(s)
  Ohka F, Ito M, Ranjit M, Senga T, Motomura A, Motomura K, Saito K, Kato K, Kato Y, Wakabayashi T, Soga T, Natsume A.
- Journal Title
  
  Tumour Biol.
  
  Volume: 1 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy.2014
- Author(s)
  Tanahashi K, Natsume A, Ohka F, Momota H, Kato A, Motomura K, Watabe N, Muraishi S, Nakahara H, Saito Y, Takeuchi I, Wakabayashi T.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2014 Pages: 860241-860241
- DOI
  10.1155/2014/860241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24590478, KAKENHI-PROJECT-25861268
[Journal Article] Effectiveness of plasma treatment on gastric cancer cells.2014
- Author(s)
  Torii K, Yamada S, Nakamura K, Tanaka H, Kajiyama H, Tanahashi K, Iwata N, Kanda M, Kobayashi D, Tanaka C, Fujii T, Nakayama G, Koike M, Sugimoto H, Nomoto S, Natsume A, Fujiwara M, Mizuno M, Hori M, Saya H, Kodera Y.
- Journal Title
  
  Gastric Cancer.
  
  Volume: 2014 Pages: 100-100
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDHI mutation2014
- Author(s)
  Ohka F,Ito M,Ranjit M,Senga T,Motomura A,Motomura K,Saito K,Kato Y, Wakabayashi T,Soga T,Natsume A
- Journal Title
  
  Tumor Biol,
  
  Volume: 35(6) Pages: 5911-5920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Assessment of tumor cells in a mouse model of diffuse infiltrative glioma by Raman spectroscopy.2014
- Author(s)
  Tanahashi K, Natsume A, Ohka F, Momota H, Kato A, Motomura K, Watabe N, Muraishi S, Nakahara H, Saito Y, Takeuchi I, Wakabayashi T
- Journal Title
  
  Biomed Res Int
  
  Volume: 20 Pages: 860241-860241
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas.2014
- Author(s)
  Suzuki A, Nobusawa S, Natsume A, Suzuki H, Kim YH, Yokoo H, Nagaishi M, Ikota H, Nakazawa T, Wakabayashi T, Ohgaki H, Nakazato Y.
- Journal Title
  
  J Neurooncol.
  
  Volume: 120 Issue: 2 Pages: 283-91
- DOI
  10.1007/s11060-014-1568-1
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24390341, KAKENHI-PROJECT-25290017
[Journal Article] Preclinical evaluation of an O6-methylguanine-DNA methyltrasferase-siRNA/liposome Complex administered by convection-enhanced delivery to rat and porcine brains2014
- Author(s)
  Tsujiuchi T,Natsume A,Motomura K,Kondo G,Ranjit M,Hachisu　R,Sugimura　I,Tomita　S,Takehara　I,Woolley　M,Barua　N,Gill　S,Bienemann　A,Yamashita　Y,Toyokuni S,Wakabayashi T
- Journal Title
  
  Am J Transl Res
  
  Volume: 6(2) Pages: 169-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Olig2 labeling index is correlated with histological and molecular classifications in low-grade diffuse gliomas.2014
- Author(s)
  Suzuki A, Nobusawa S, Natsume A, Suzuki H, Kim YH, Yokoo H, Nagaishi M, Ikota H, Nakazawa T, Wakabayashi T, Ohgaki H, Nakazato Y
- Journal Title
  
  J Neurooncol
  
  Volume: 120 Pages: 283-91
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Association of dorsal inferior frontooccipital fasciculus fibers in the deep parietal lobe with both reading and writing processes: a brain mapping study2014
- Author(s)
  Motomura K, Fujii M, Maesawa S, Kuramitsu S, Natsume A, Wakabayashi T
- Journal Title
  
  J Neurosurg
  
  Volume: 121 Pages: 142-148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Blockade of gap junction hemichannel protects secondary spinal cord injury from activated microglia-mediated glutamate exito-neurotoxicity.2014
- Author(s)
  Umebayashi D, Natsume A, Takeuchi H, Hara M, Nishimura Y, Fukuyama R, Sumiyoshi N, Wakabayashi T.
- Journal Title
  
  J Neurotrauma.
  
  Volume: 1 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Novel somatic and germline mutations in intracranial germ cell tumours.2014
- Author(s)
  Wang L, Yamaguchi S, Burstein MD, Terashima K, Chang K, Ng HK, Nakamura H, He Z, Doddapaneni H, Lewis L, Wang M, Suzuki T, Nishikawa R, Natsume A, Terasaka S, Dauser R, Whitehead W, Adekunle A, Sun J, Qiao Y, Marth G, Muzny DM, Gibbs RA, Leal SM, Wheeler DA, Lau CC.
- Journal Title
  
  Nature
  
  Volume: 511 Issue: 7508 Pages: 241-245
- DOI
  10.1038/nature13296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Novel somatic and germline mutations in intracranial germ cell tumours.2014
- Author(s)
  Wang L, Yamaguchi S, Burstein MD, Terashima K, Chang K, Ng HK, Nakamura H, He Z, Doddapaneni H, Lewis L, Wang M, Suzuki T, Nishikawa R, Natsume A, Terasaka S, Dauser R, Whitehead W, Adekunle A, Sun J, Qiao Y, Marth G, Muzny DM, Gibbs RA, Leal SM, Wheeler DA, Lau CC
- Journal Title
  
  Nature
  
  Volume: 511 Pages: 241-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts2013
- Author(s)
  Masasuke Ohno, Takayuki Ohkuri, Akemi Kosaka, Kuniaki Tanahashi, Carl H June, Atsushi Natsume, Hideho Okada
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 1 Issue: 1 Pages: 112-112
- DOI
  10.1186/2051-1426-1-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861270
[Journal Article] A novel monoclonal antibody GMab-m1 specifically recognizes IDH1-R132G mutation.2013
- Author(s)
  Kato Y, Natsume A, Kaneko MK.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 432 Issue: 4 Pages: 564-567
- DOI
  10.1016/j.bbrc.2013.02.049
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-23701043, KAKENHI-PROJECT-25462242
[Journal Article] Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma.2013
- Author(s)
  Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, Issa JP, Sekido Y, Kondo Y.
- Journal Title
  
  Cancer Res.
  
  Volume: 15 Issue: 14 Pages: 4559-4570
- DOI
  10.1158/0008-5472.can-13-0109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-25290048
[Journal Article] The role of PLK1-phosphorylated SVIL in myosin II activation and cytokinetic furrowing.2013
- Author(s)
  Hasegawa H, Hyodo T, Asano E, Ito S, Maeda M, Kuribayashi H, Natsume A, Wakabayashi T, Hamaguchi M, Senga T.
- Journal Title
  
  J Cell Sci.
  
  Volume: 126 Pages: 3627-3637
- DOI
  10.1242/jcs.124818
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24249073
[Journal Article] Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma2013
- Author(s)
  Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, Sato S, Takahashi S, Ishikawa Y, Takeuchi I, Shimogawa H, Uesugi M, Okano H, Kim SU, Wakabayashi T, Issa JP, Sekido Y, Kondo Y
- Journal Title
  
  Cancer Research
  
  Volume: 73 Pages: 4559-4570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Lack of presence of the human cytomegalovirus in human glioblastoma.2013
- Author(s)
  Yamashita Y, Ito Y, Isomura H, Takemura N, Okamoto A, Motomura K, Tsujiuchi T, Natsume A, Wakabayashi T, Toyokuni S, Tsurumi T
- Journal Title
  
  Mod Pathol
  
  Volume: Dec 13 Issue: 7 Pages: 922-9
- DOI
  10.1038/modpathol.2013.219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590394, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24249073, KAKENHI-PROJECT-24390341, KAKENHI-PROJECT-25861268, KAKENHI-PROJECT-26461581
[Journal Article] A hypoxia-inducible factor (HIF)-3a splicing variant, HIF・3a4 impairs angiogenesis in hypervascular malignant meningiomas with epigenetically silenced HIF-3α42013
- Author(s)
  Ando H, Natsume A, Iwami K, Ohka F, Kuchimaru T, Kizaka-Kondoh S, Ito K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: (in press) Issue: 1 Pages: 139-144
- DOI
  10.1016/j.bbrc.2013.02.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04973, KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24249073, KAKENHI-PLANNED-22112009
[Journal Article] Adoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma model.2013
- Author(s)
  Iwami K, Natsume A, Ohno M, Ikeda H, Mineno J, Nukaya I, Okamoto S, Fujiwara H, Yasukawa M, Shiku H, Wakabayashi T.
- Journal Title
  
  Neuro Oncol.
  
  Volume: 15 Issue: 6 Pages: 747-758
- DOI
  10.1093/neuonc/not007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010, KAKENHI-PROJECT-24249073, KAKENHI-PROJECT-24390245, KAKENHI-PROJECT-24390300, KAKENHI-PROJECT-24591426
[Journal Article] Spinal intradural cystic venous angioma originating from a nerve root in the cauda equina.2013
- Author(s)
  Nishimura Y, Hara M, Natsume A, Nakajima Y, Fukuyama R, Wakabayashi T, Ginsberg HJ.
- Journal Title
  
  J Neurosurg Spine.
  
  Volume: 19 Pages: 716-720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249073
[Journal Article] Contribution of microRNA-1275 to Claudinll protein suppression via apolycomb-mediated silencing mechanism in human glioma stem-like cellS.2012
- Author(s)
  Katsushima K, Shinjo K, Natsume A, Ohka F, Fujii M, Osada H, Sekido y Kondo Y.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287 Pages: 27396-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Correlation between quantified promoter methylation and enzymatic activity of O (6)-methylguanine-DNA methyltransferase in glioblastomas2012
- Author(s)
  Kishida Y, Natsume A, et al
- Journal Title
  
  Tumour Biol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Epigenetic subdassification of meningiomas based on genome-wide DNA methylation analyses2012
- Author(s)
  Kishida Y, Natsume A, et al
- Journal Title
  
  Carcinogenesis
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Girdin maintains the sternness of glioblastoma stem cells.2012
- Author(s)
  Natsume A, Kato T, Kinjo S, Enomoto A, Toda H, Shimato S, Ohka F, Motomura K, Kondo Y, Miyata T, Takahashi M, Wakabayashi T.
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 2715-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas2012
- Author(s)
  Motomura K, Natsume A, et al
- Journal Title
  
  J Neurooncol
  
  Volume: 106 Pages: 209-11
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Immunohistochemical analysis-based proteomic subclassification of newly diagnosed glioblastomas.2012
- Author(s)
  Motomura K, Natsume A, Watanabe R, Ito l, Kato Y, Momota H, Nishikawa R, Mishima K, Nakasu Y; Abe I, Namba H, Nakazato Y, Tashiro H, Takeuchi I, Mori T, Wakabayashi T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 103 Pages: 1871-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390341
[Journal Article] Benefits of interferon-bet a and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter2011
- Author(s)
  Motomura, K., Natsume, A., Kishida, Y., Higashi, H., Kondo, Y., Nakasu, Y., Abe, T., Namba, H., Wakai, K., and Wakabayashi, T
- Journal Title
  
  Amulticenter study
  
  Volume: 117 Pages: 1721-1730
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma2011
- Author(s)
  Ohka F, Natsume A, et al
- Journal Title
  
  PloS ONE
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] The global DNA methylati on surrogate LINE-1 methylation is correlated with MGMT promoter methylation and is a better prognostic factor for glioma2011
- Author(s)
  Ohka, F., Natsume, A., Motomura, K., Kishida, Y., Kondo, Y., Abe, T., Nakasu, Y., Namba, H., Wakai, K., Fukui, T
- Journal Title
  
  PLoS One
  
  Volume: 6 Pages: 23332-23332
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Cytokine networks in glioma2011
- Author(s)
  Iwami K, Natsume A, Wakabayashi T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 第34巻 Pages: 253-264
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Intravenousad ministration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas2011
- Author(s)
  Motomura, K., Natsume, A., andWakabayashi, T
- Journal Title
  
  J Neurooncol
  
  Volume: 106 Pages: 209-211
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide2011
- Author(s)
  Motomura K, Natsume A, Fujii M, Ito M, Momota H, Wakabayashi T
- Journal Title
  
  Leukemia and Lymphoma Epub ahead of print
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, if osfamide and carboplatin chemotherapy and whole-brain radiation therapy2011
- Author(s)
  Motomura, K., Natsume, A., Fujii, M., Ito, M., Momota, H., and Wakabayashi, T
- Journal Title
  
  Leuk Lymphoma
  
  Volume: 52 Pages: 2069-75
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promotor methylation and is a better prognostic factor for glioma2011
- Author(s)
  Ohka F, Natsume A, Motomura K, KishidaY, Kondo Y, Abe T, Nakasu Y, Namba H, Wakai K, Fukui T, Momota H, Iwami K, Kinjo S, Ito M, Fujii M, Wakabayashi T
- Journal Title
  
  PLoS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Benefits of interferon-beta and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter2011
- Author(s)
  Motomura K, Natsume A, Kishida Y, Higashi H, Kondo Y, Nakasu Y, Abe T, Namba H, Wakai K, Wakabayashi T.
- Journal Title
  
  A multicenter study
  
  Volume: 117 Pages: 1721-1730
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas2011
- Author(s)
  Motomura K, Natsume A, Wakabayashi T
- Journal Title
  
  J Neurooncol
  
  Volume: 13
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Glioma-initiating cells and molecular pathology2011
- Author(s)
  Natsume A, Kinjo S, Yuki K, Kato T, Ohno M, Motomura K, Iwami K, Wakabayashi T
- Journal Title
  
  Implications for therapy Brain
  
  Volume: 28 Pages: 1-28
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] A multicenter phase I trial of combination therapy with interferon-beta and temozolomide for high-grade gliomas(INTEGRA study) the final report2011
- Author(s)
  Wakabayashi T, Kayama T, Nishikawa R, Takahashi H, Hoshimoto N, TakahashiJ, Aoki T, Sugiyama K, Ogura M, Natsume A, Yoshida J.
- Journal Title
  
  J Neurooncol
  
  Volume: 14
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Epigenetic subclassification of meningiomas based on genome-wide DNA methylation analyses2011
- Author(s)
  Kishida Y, Natsume A, Kondo Y, Takeuchi I, An B, Okamoto Y, Shinjo K, Saito K, AndoH, Ohka F, Sekido Y, Wakabayashi T
- Journal Title
  
  Carcinogenesis
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] A multicenter phase I trial of combination therapy with interferon-beta and temozolomide for high-grade gliomas(INTEGRA study)2011
- Author(s)
  Wakabayashi, T., Kayama, T., Nishikawa, R., Takahashi, H., Hashimoto, N., Takahashi, J., Aoki, T., Sugiyama, K., Ogura, M., Natsume, A., and Yoshida, J
- Journal Title
  
  J Neurooncol
  
  Volume: 104 Pages: 573-577
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Rhabdoid glioblastoma in a child2011
- Author(s)
  Momota H, Iwami K, Fujii M, MotomuraK, Natsume A, Ogino J, Hasegawa T, Wakabayashi T
- Journal Title
  
  case report and literature review
  
  Volume: 28 Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Rhabdoid glioblastoma in a child : case report and literature review2011
- Author(s)
  Momota, H., Iwami, K., Fujii, M., Motomura, K., Natsume, A., Ogino, J., Hasegawa, T., and Wakabayashi, T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28 Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy2011
- Author(s)
  Motomura K, Natsume A, Wakabayashi T
- Journal Title
  
  Leukemia and Lymphoma
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] The global DNA methylation surrogate LINE-1 methylation is correlated with MGMT promotor methylation and is a better prognostic factor for glioma2011
- Author(s)
  Ohka F, Natsume A, Wakabayashi T
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Long-term survival in patients with newly diagnosed primary central nervous system lymphoma treated with dexamethasone, etoposide, ifosfamide and carboplatin chemotherapy and whole-brain radiation therapy2011
- Author(s)
  Motomura K, Natsume A, et al
- Journal Title
  
  Leuk Lymphoma
  
  Volume: I52 Pages: 2069-75
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107010
[Journal Article] Cytokine networks in glioma2011
- Author(s)
  Iwami, K., Natsume, A., and Wakabayashi, T
- Journal Title
  
  Neurosurg Rev
  
  Volume: 34
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Girdin maintains the stemness of glioblastoma stem cells2011
- Author(s)
  Natsume A, at al
- Journal Title
  
  Oncogene
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Girdin maintains the stemness of glioblastoma stem cells2011
- Author(s)
  Natsume A, Kato T, Kinjo S, Enomoto A, TodaH, Shimato S, Ohka F, Motomura K, Kondo Y, Miyata T, Takahashi M, Wakabayashi T
- Journal Title
  
  Oncogene
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Glioma-initiating cells and molecular pathology : implications for therapy2011
- Author(s)
  Natsume, A., Kinjo, S., Yuki, K., Kato, T., Ohno, M., Motomura, K., Iwami, K., andWakabayashi, T
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: 28 Pages: 1-12
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation2010
- Author(s)
  Motomura K, Ogura M, Natsume A, Yokoyama H, Wakabayashi T
- Journal Title
  
  Neurosci Lett
  
  Volume: 485 Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells2010
- Author(s)
  Kato T, Natsume A, et al
- Journal Title
  
  Gene Therapy
  
  Volume: 17 Pages: 1363-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Retrovirally engineered T-cell-based immunotherapy targeting type-III variant epidermal growth factor receptor, a glioma-associated antigen2010
- Author(s)
  Ohno M, Natsume A, et al
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2518-24
- NAID
  10027834208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas.2010
- Author(s)
  Natsume A, Kondo Y, Ito M, Motomura K, Wakabayashi T, Yoshida J.
- Journal Title
  
  Cancer Sci 101
  
  Pages: 1331-1336
- NAID
  10026592977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Retro virally engineered T-cell-based immunotherapy targeting type III variant epidermal growth factor receptor, a glioma-associated antigen2010
- Author(s)
  Ohno, M., Natsume, A., Ichiro Iwami, K., Iwamizu, H., Noritake, K., Ito, D., Toi, Y., Ito, M., Motomura, K., Yoshida, J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2518-2524
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma2010
- Author(s)
  Ito, S., Natsume, A., Shimato, S., Ohno, M., Kato, T., Chansakul, P., Wakabayashi, T., and Kim, S. U
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 17 Pages: 299-306
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Retrovirally engineered T-cell-based immunotherapy targeting type-III variant epidermal growth factor receptor, a glioma-associated antigen2010
- Author(s)
  Ohno M, Natsume A, Iwami K, Iwamizu H, Noritake K, Ito D, Toi Y, Ito M, Kazuya M, Yoshida J, Yoshikawa K Wakabayashi T
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 2518-2524
- NAID
  10027834208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas2010
- Author(s)
  Natsume, A., Kondo, Y., Ito, M., Motomura, K., Wakabayashi, T., and Yoshida, J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 1331-1336
- NAID
  10026592977
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Gene therapy for high-grade glioma2010
- Author(s)
  Iwami, K., Natsume, A.
- Journal Title
  
  Neurol Med Chir
  
  Volume: 50 Pages: 727-736
- NAID
  10030693008
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma2010
- Author(s)
  Ito S, Natsume A, Shimato S, Ohno M, Kato T, Chansakul P, Wakabayashi T, Kim SU
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: 17 Pages: 299-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Retrovirally engineered T cell-based immunotherapy targeting type-III variant epidermal growth factor receptor, a gloma-associated antigen2010
- Author(s)
  M Ohno, A Natsume, H Iwamizu, D Ito, Y Toi, K Iwami, K Noritake, M Ito, KMotomura, J Yoshida, K Yoshikawa, T Wakabayashi
- Journal Title
  
  Cancer Scinece
  
  Volume: 101(12) Pages: 2518-2524
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas2010
- Author(s)
  A Natsume, Y Kondo, M Ito, K Momota, T Wakabayashi, J Yohida
- Journal Title
  
  Cancer Scinece
  
  Volume: 101(6) Pages: 1331-1336
- NAID
  10026592977
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas2010
- Author(s)
  Natsume A, Kondo Y, Ito M, Motomura K, Wakabayashi T, Yoshida J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 1331-1336
- NAID
  10026592977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation2010
- Author(s)
  Motomura, K., Ogura, M., Natsume, A., Yokoyama, H., and Wakabayashi, T
- Journal Title
  
  Neurosci Lett
  
  Volume: 485 Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Retrovirally engineered T-cell-based immunotherapy targeting type-III variant epidermal growth factor receptor, a glioma-associated antigen2010
- Author(s)
  Ohno M, Natsume A, et al
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 2518-24
- NAID
  10027834208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells2010
- Author(s)
  T Kato, A Natsume, H Toda, H Iwazumi, T Sugita, R Hachisu, R Watanabe, KYuki, K Motomura, K Bankiewicz, T Wakabayashi
- Journal Title
  
  Gene Therapy
  
  Volume: 17(11) Pages: 1363-1371
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Human neural stem cells transduced with IFN-beta and cytosine deaminase genes intensify bystander effect in experimental glioma2010
- Author(s)
  S Ito, A Natsume, S Shimato, M Ohno, T Kato, P Chansakul, T Wakabayashi, SUKim.
- Journal Title
  
  Cancer Gene Ther
  
  Volume: 17 Pages: 299-306
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells.2010
- Author(s)
  Kato T, Natsume A, Toda H, Iwamizu H, Sugita T, Hachisu R, Watanabe R, Yuki K, Motomura K, Bankiewicz K, Wakabayashi T
- Journal Title
  
  Gene Therapy 17
  
  Pages: 1363-1371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation2010
- Author(s)
  Motomura K, Ogura M, Natsume A, Yokoyama H, Wakabayashi T
- Journal Title
  
  Neuroscience Letters
  
  Volume: 485(1) Pages: 65-70
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Benefits of interferon-beta and temozolomide combination therapy for newly diagnosed primary glioblastoma with the unmethylated MGMT promoter : a multicenter study2010
- Author(s)
  Motomura, K., Natsume, A., Kishida, Y., Higashi, H., Kondo, Y., Nakasu, Y., Abe, T., Namba, H., Wakai, K., and Wakabayashi, T
- Journal Title
  
  Cancer
  
  Volume: 117 Pages: 1721-30
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells2010
- Author(s)
  Kato T, Natsume A, Toda H, Iwamizu H, Sugita T, Hachisu R, Watanabe R, Yuki K, Motomura K, Bankiewicz K, Wakabayashi T
- Journal Title
  
  Gene Therapy
  
  Volume: 17 Pages: 1363-1371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas2010
- Author(s)
  Natsume A, et al
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1331-6
- NAID
  10026592977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Epigenetic aberrations and therapeutic implications in gliomas2010
- Author(s)
  Natsume A, et al
- Journal Title
  
  Cancer Science
  
  Volume: 101 Pages: 1331-6
- NAID
  10026592977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells2010
- Author(s)
  Kato T, Natsume A, et al
- Journal Title
  
  Gene Therapy
  
  Volume: 17 Pages: 1363-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390409
[Journal Article] Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells2010
- Author(s)
  Kato, T., Natsume, A., Toda, H., Iwamizu, H., Sugita, T., Hachisu, R., Watanabe, R., Yuki, K., Motomura, K., Bankiewicz, K., and Wakabayashi, T
- Journal Title
  
  Gene Ther
  
  Volume: 17 Pages: 1363-1371
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Type I Interferon Inhibits Astrocytic Gliosis and Promotes Functional Recovery after Spinal Cord Injury by Deactivation of the MEK/ERK Pathway.2009
- Author(s)
  Ito M, Natsume A, Takeuchi H, et al.
- Journal Title
  
  Journal of Neurotrauma 26
  
  Pages: 41-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas.2009
- Author(s)
  Wakabayashi T, Natsume A, Hatano H, Fujii M, Shimato S, Ito M, Ohno M, Ito S, Ogura M, Yoshida J.
- Journal Title
  
  Neurosurgery 64
  
  Pages: 455-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling2009
- Author(s)
  Yuki, K., Natsume, A., Yokoyama, H., Kondo, Y., Ohno, M., Kato, T., Chansakul, P., Ito, M., Kim, S. U., and Wakabayashi, T
- Journal Title
  
  Cancer Lett
  
  Volume: 284 Pages: 71-79
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas2009
- Author(s)
  Wakabayashi, T., Natsume, A., Hatano, H., Fujii, M., Shimato, S., Ito, M., Ohno, M., Ito, S., Ogura, M., and Yoshida, J
- Journal Title
  
  Neurosurgery
  
  Volume: 64
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells2009
- Author(s)
  Oi S, Natsume A, Ito M
- Journal Title
  
  J Neurooncol 92(1)
  
  Pages: 15-22
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Type I Interferon Inhibits Astrocytic Gliosis and Promotes Functional Recovery after Spinal Cord Injury by Deactivation of the MEK/ERK Path way.2009
- Author(s)
  Ito M, Natsume A, Takeuchi H, et al.
- Journal Title
  
  J Neurotrauma 26
  
  Pages: 41-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] The modulation of MicroRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma2009
- Author(s)
  Ohno M, Natsume A Kondo Y, Iwamizu H, Motomura K, Toda H, Ito M, Kato T, Wakabayashi T
- Journal Title
  
  Mol Cancer Res 7
  
  Pages: 2002-2030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling2009
- Author(s)
  Yuki K, Natsume A, Yokoyama H, Kondo Y, Ohno M, Kato T, Chansakul P, Ito M, Kim SU, Wakabayashi T.
- Journal Title
  
  Cancer Lett 284
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas.2009
- Author(s)
  Wakabayashi T, Natsume A., Hatano H, et al.
- Journal Title
  
  Neurosurgery 64
  
  Pages: 461-452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas2009
- Author(s)
  Wakabayashi T, Natsume A, Hatano H, Fujii M, Shimato S, Ito M, Ohno M, Ito S, Ogura M, Yoshida J.
- Journal Title
  
  Neurosurgery 64
  
  Pages: 455-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] The modulation of MicroRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma2009
- Author(s)
  Ohno M, Natsume A, Kondo Y, Iwamizu H, Motomura K, Toda H, Ito M, Kato T, Wakabayashi T.
- Journal Title
  
  Mol.Cancer Res 7
  
  Pages: 2022-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma2009
- Author(s)
  Ohno M, Natsume A, Fujii M
- Journal Title
  
  Pediatr Blood Cancer (in press)
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma.2009
- Author(s)
  Ohno M, Natsume A, Fujii M, et al.
- Journal Title
  
  Pediatr Blood Cancer (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells2009
- Author(s)
  Oi, S., Natsume, A., Ito, M., Kondo, Y., Shimato, S., Maeda, Y., Saito, K., andWakabayashi, T
- Journal Title
  
  J Neurooncol
  
  Volume: 92 Pages: 15-22
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma2009
- Author(s)
  Ohno M, Natsume A Fujii M, Ito M, Wakabayashi T
- Journal Title
  
  Pediatr Blood Cancer 53
  
  Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells2009
- Author(s)
  Oi S, Natsume A, Ito M, Kondo Y, Shimato S, Maeda Y, Saito K, Wakabayashi T.
- Journal Title
  
  J Neuro-oncology 92
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells2009
- Author(s)
  Oi S, Natsume A, Ito M, Kondo Y, Shimato S, Maeda Y, Saito K, Wakabayashi T
- Journal Title
  
  J Neurooncol 92
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Synergistic induction of NY-ESO-1antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxyoytidine in glioma cells.2009
- Author(s)
  Oi S, Natsume A. Ito M, Kondo Y, Shimato S, Maeda Y, Saito K, Wakabayashi T.
- Journal Title
  
  J Neurooncol. 92
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma2009
- Author(s)
  Ohno, M., Natsume, A., Kondo, Y., Iwamizu, H., Motomura, K., Toda, H., Ito, M., Kato, T., and Wakabayashi, T
- Journal Title
  
  Mol Cancer Res
  
  Volume: 7 Pages: 2022-2030
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Induction of oligodendrogenesis in glioblastoma-initiating cells by IFN-mediated activation of STAT3 signaling2009
- Author(s)
  Yuki K, Natsume A, Yokoyama H, Kondo Y, Ohno M, Kato T, Chansakul P, Ito M, Kim SU, Wakabayashi T
- Journal Title
  
  Cancer Lett 284
  
  Pages: 71-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas2009
- Author(s)
  Wakabayashi T, Natsume A Hatano H, Fujii M, Shimato S, Ito M, Ohno M, Ito S, Ogura M, Yoshida J
- Journal Title
  
  Neurosurgery 64
  
  Pages: 455-461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.2009
- Author(s)
  Oi S, Natsume A, Ito M, et al.
- Journal Title
  
  J Neurooncol 92
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma2009
- Author(s)
  Ohno, M., Natsume, A., Fujii, M., Ito, M., and Wakabayashi, T
- Journal Title
  
  Pediatr Blood Cancer
  
  Volume: 53 Pages: 37-41
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Type I Interferon Inhibits Astrocytic Gliosis and Promotes Functional Recovery after Spinal Cord Injury by Deactivation of the MEK/ERK Pathway2009
- Author(s)
  Ito M, Natsume A, Takeuchi H
- Journal Title
  
  J Neurotrauma 26(1)
  
  Pages: 41-53
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway2009
- Author(s)
  Ito M, Natsume A, Takeuchi H, Shimato S, Ohno M, Wakabayashi T, Yoshida J
- Journal Title
  
  J Neurotrauma 26
  
  Pages: 41-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma2009
- Author(s)
  Ohno M, Natsume A, Fujii M, Ito M, Wakabayashi T
- Journal Title
  
  Pediatr Blood Cancer
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Type I Interferon Inhibits Astrocytic Gliosis and Promotes Functional Recovery after Spinal Cord Injury by Deactivation of the MEK/ERK Pathway2009
- Author(s)
  Ito M, Natsume A, Takeuchi H, Shimato S, Ohno M, Wakabayashi T, Yoshida J
- Journal Title
  
  J Neurotrauma 26
  
  Pages: 41-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway2009
- Author(s)
  Ito, M., Natsume, A., Takeuchi, H., Shimato, S., Ohno, M., Wakabayashi, T., and Yoshida, J
- Journal Title
  
  J Neurotrauma
  
  Volume: 26 Pages: 41-53
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.2009
- Author(s)
  Oi S, Natsume A, Ito M, Kondo Y, Shimato S, Maeda Y, Saito K, Wakabayashi T
- Journal Title
  
  J Neurooncol 92
  
  Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas2009
- Author(s)
  Wakabayashi T, Natsume A, Hatano H
- Journal Title
  
  Neurosurgery 64(3)
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Advanced new neurosurgical procedure using integrated system of intraoperative MRI and neuronavigation with multimodal neuroradiological images2009
- Author(s)
  Wakabayashi, T., Fujii, M., Kajita, Y., Natsume, A., Maezawa, S., and Yoshida, J
- Journal Title
  
  Nagoya J Med Sci
  
  Volume: 71 Pages: 101-107
- NAID
  110007355139
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] p16 promoter methylation in the serum as a basis for the molecular diagnosis of gliomas2009
- Author(s)
  Wakabayashi T, Natsume A, Hatano H, Fujii M, Shimato S, Ito M, Ohno M, Ito S, Ogura M, Yoshida J
- Journal Title
  
  Neurosurgery 64
  
  Pages: 455-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Type I interferon inhibits astrocytic gliosis and promotes functional recovery after spinal cord injury by deactivation of the MEK/ERK pathway2009
- Author(s)
  Ito M, Natsume A, Takeuchi H, Shimato S, Ohno M, Wakabayashi T, Yoshida J.
- Journal Title
  
  J Neurotrauma 26
  
  Pages: 41-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390408
[Journal Article] Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen2008
- Author(s)
  Shimato S, Natsume A, Wakabayashi T, Tsujimura K, Nakahara N, Ishii J, Ito M, Akatsuka Y, Kuzushima K, Yoshida J
- Journal Title
  
  Jpn J Clin Oncol 38
  
  Pages: 715-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.2008
- Author(s)
  Natsume A, Wakabayashi T, Tsujimura K, Shimato S, Ito M, Kuzushima K, Kondo Y, Sekido Y, Kawatsura H, Narita Y, Yoshida J
- Journal Title
  
  Int J Cancer. 122
  
  Pages: 2542-2553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591710
[Journal Article] Gene therapy for high-grade glioma : current approaches and future directions2008
- Author(s)
  Natsume A, Yoshida J
- Journal Title
  
  Cell Adh Migr 2
  
  Pages: 186-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] A phase I clinical trial of interferon-beta gene therapy for high-grade glioma : novel findings from gene expression profiling and autopsy2008
- Author(s)
  Wakabayashi T, Natsume A, Hashizume Y, Fujii M, Mizuno M, Yoshida J
- Journal Title
  
  J Gene Med 10
  
  Pages: 329-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.2008
- Author(s)
  Natsume A, Wakabayashi T, Tsujimura K, et al.
- Journal Title
  
  International Journal of Cancer 122
  
  Pages: 2542-2553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.2008
- Author(s)
  Natsume A, Wakabayashi T, Tsujimura K, et al.
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2542-2553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Gene therapy for high-grade glioma : current approaches and future directions.2008
- Author(s)
  Natsume A, Yoshida J
- Journal Title
  
  Cell Adh Migr 2
  
  Pages: 186-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Gene therapy for high-grade glioma : current approaches and future directions2008
- Author(s)
  Natsume A, Yoshida J
- Journal Title
  
  Cell Adh Migr 2(3)
  
  Pages: 186-191
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] A phase I clinical trial of interferon-beta gene therapy for high-grade glioma : novel findings from gene expression profiling and autopsy.2008
- Author(s)
  Wakabayashi T, Natsume A, Hashizume Y, et al.
- Journal Title
  
  J Gene Med 10
  
  Pages: 329-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas2008
- Author(s)
  Gao W, Kondo Y, Shen L, Shimizu Y, Sano T, Yamao K, Natsume A, Goto Y, Ito M, Murakami H, Osada H, Zhang J, et.al.
- Journal Title
  
  Carcinogenesis 29
  
  Pages: 1901-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] A combination of IFN-beta and temozolomide in human glioma xenograft models : implication of p53-mediated MGMT downregulation2008
- Author(s)
  Natsume A, Wakabayashi T, Ishii D, Maruta H, Fujii M, Shimato S, Ito M, Yoshida J
- Journal Title
  
  Cancer Chemother Pharmacol 61
  
  Pages: 653-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] A phase I clinical trial of interferon-beta gene therapy for high- grade glioma : novel findings from gene expression profiling and autopsy2008
- Author(s)
  Wakabayashi T, Natsume A, Hashizume Y
- Journal Title
  
  J Gene Med 10(4)
  
  Pages: 329-339
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] A combination of IFN-beta and temozolomide in human glioma xenograft models : implication of p53-inediated MGMT downregulation.2008
- Author(s)
  Natsume A, Wakabayashi T, Ishii D, et al.
- Journal Title
  
  Cancer Chemother Pharmacol 61
  
  Pages: 653-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma2008
- Author(s)
  Natsume A, Wakabayashi T, Tsujimura K
- Journal Title
  
  Int J Cancer 122(11)
  
  Pages: 2542-2553
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] A combination of IFN-beta and temozolomide in human glioma xenograft models : implication of p53-mediated MGMT downregulation2008
- Author(s)
  Natsume A, Wakabayashi T, Ishii D
- Journal Title
  
  Cancer Chemother Pharmacol 61(4)
  
  Pages: 653-659
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen2008
- Author(s)
  Shimato S, Natsume A, Wakabayashi T
- Journal Title
  
  J Neurosurg 109(1)
  
  Pages: 117-122
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma2008
- Author(s)
  Natsume A, Wakabayashi T, Tsujimura K, Shimato S, Ito M, Kuzushima K, Kondo Y, Sekido Y, Kawatsura H, Narita Y, Yoshida J
- Journal Title
  
  Int J Cancer 122
  
  Pages: 2542-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen2008
- Author(s)
  Shimato S, Natsume A, Wakabayashi T, Tsujimura K, Nakahara N, Ishii J, Ito M, Akatsuka Y, Kuzushima K, Yoshida J
- Journal Title
  
  J Neurosurg 109
  
  Pages: 117-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Identification of a human leukocyte antigen-A24-restricted T-cell epitope derived from interleukin-13 receptor alpha2 chain, a glioma-associated antigen.2008
- Author(s)
  Shimato S, Natsume A, Wakabayashi T, et al.
- Journal Title
  
  J Neurosurg 109
  
  Pages: 117-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Genetically heterogeneous glioblastoma recurring with disappearance of 1p/19q losses : case report2007
- Author(s)
  Ito M, Wakabayashi T, Natsume A, Hatano H, Fujii M, Yoshida J
- Journal Title
  
  Neurosurgery 61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas2007
- Author(s)
  Ishii D, Natsume A, Wakabayashi T
- Journal Title
  
  Neurol Med Chir (Tokyo) 47(8)
  
  Pages: 341-349
- NAID
  110006368605
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma.2007
- Author(s)
  Shimato S, Natsume A. Takeuchi H, Wakabayashi T, Fujii M, Ito M, Ito S, Park IH, Bang JH, Kim SU, Yoshida J.
- Journal Title
  
  Gene Therapy 14
  
  Pages: 1132-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress2007
- Author(s)
  Ishii J, Natsume A, Wakabayashi T, Takeuchi H, Hasegawa H, Kim SU, Yoshida J
- Journal Title
  
  Neurosci Lett 423
  
  Pages: 225-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma2007
- Author(s)
  Shimato S, Natsume A, Takeuchi H
- Journal Title
  
  Gene Ther 14(15)
  
  Pages: 1132-1142
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells2007
- Author(s)
  Tsuno T, Natsume A, Katsumata S
- Journal Title
  
  J Neurooncol 83(3)
  
  Pages: 249-258
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress.2007
- Author(s)
  Ishii J, Natsume A, Wakabayashi T, Takeuchi H, Hasegawa H, Kim SU, Yoshida J.
- Journal Title
  
  Neuroscience Letters 423
  
  Pages: 225-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Genetically heterogenous glioblastoma recurring with disappearance of 1p/19q losses: case report2007
- Author(s)
  Ito M, Wakabayashi T, Natsume A, Hatano H, Fujii M, Yoshida J.
- Journal Title
  
  Neurosurgery 61
  
  Pages: 168-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner2007
- Author(s)
  Takeuchi H, Natsume A, Wakabayashi T
- Journal Title
  
  Neurosci Lett 426(2)
  
  Pages: 69-74
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Malignant transformation-related genes in meningioma: allelic loss on 1 p36 and methylation status of p73 and RASSF1A2007
- Author(s)
  Nakane Y, Natsume A, Wakabayashi T, Oi S, Ito M, Inao S, Saito K, Yoshida J.
- Journal Title
  
  J Neurosurg 107
  
  Pages: 398-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] The free-radical scavenger edaravone restores the differentiation of human neural precursor cells after radiation-induced oxidative stress2007
- Author(s)
  Ishii J, Natsume A, Wakabayashi T
- Journal Title
  
  Neurosci Lett 423(3)
  
  Pages: 225-230
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells2007
- Author(s)
  Tsuno T, Natsume A, Katsumata S, Mizuno M, Fujita M, Osawa H, Nakahara N, Wakabayashi T, Satoh Y, Inagaki M, Yoshida J
- Journal Title
  
  J Neurooncol 83
  
  Pages: 249-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Malignant transformation-related genes in meningiomas : allelic loss on 1p36 and methylation status of p73 and RASSF1A2007
- Author(s)
  Nakane Y, Natsume A, Wakabayashi T
- Journal Title
  
  J Neurosurg 107(2)
  
  Pages: 398-404
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner.2007
- Author(s)
  Takeuchi H, Natsume A, Wakabayashi T, Aoshima C, Shimato S, Ito M, Ishii J, Maeda Y, Hara M, Kim SU, Yoshida J.
- Journal Title
  
  Neuroscience Letters 426
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Malignant transformation-related genes in meningiomas : allelic loss on 1p36 and methylation status of p73 and RASSF1A2007
- Author(s)
  Nakane Y, Natsume A, Wakabayashi T, Oi S, Ito M, Inao S, Saito K, Yoshida J
- Journal Title
  
  J Neurosurg 107
  
  Pages: 398-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Efficacy of temozolomide is correlated with 1p Loss and Methylation of the Deoxyribonucleic Acid Repair Gene MGMT in Malignant Gliomas2007
- Author(s)
  Ishii D, Natsume A, Wakabayashi T, Hatano H, Asano Y, Takeuchi H, Shimato S, Ito M, Fujii M, Yoshida J.
- Journal Title
  
  Neurol Med Chir (Tokyo) 47
  
  Pages: 341-350
- NAID
  110006368605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Efficacy of temozolomide is correlated with 1p loss and methylation of the deoxyribonucleic acid repair gene MGMT in malignant gliomas2007
- Author(s)
  Ishii D, Natsume A, Wakabayashi T, Hatano H, Asano Y, Takeuchi H, Shimato S, Ito M, Fujii M, Yoshida J
- Journal Title
  
  Neurol Med Chir(Tokyo) 47
  
  Pages: 341-9
- NAID
  110006368605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Genetically heterogeneous glioblastoma recurring with disappearance of 1p/19q losses : case report2007
- Author(s)
  Ito M, Wakabayashi T, Natsume A
- Journal Title
  
  Neurosurgery 61(1)
- Data Source
  KAKENHI-PROJECT-19591669
[Journal Article] Takeuchi H, Natsume A, Wakabayashi T, Aoshima C, Shimato S, Ito M, Ishii J, Maeda Y, Hara M, Kim SU, Yoshida J2007
- Author(s)
  Takeuchi H, Natsume A, Wakabayashi T, Aoshima C, Shimato S, Ito M, Ishii J, Maeda Y, Hara M, Kim SU, Yoshida J
- Journal Title
  
  Neurosci Lett 426
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] Human neural stem cells target and deliver therapeutic gene to experimental leptomeningeal medulloblastoma2007
- Author(s)
  Shimato S, Natsume A, Takeuchi H, Wakabayashi T, Fujii M, Ito M, Ito S, Park IH, Bang JH, Kim SU, Yoshida J
- Journal Title
  
  Gene Ther 14
  
  Pages: 1132-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591671
[Journal Article] IFN-beta down-regulates the expression of DNA-repair gene. MGMT, and sensitizes resistant glioma cells to temozolomide.2005
- Author(s)
  Natsume A, et al.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7573-7579
- Data Source
  KAKENHI-PROJECT-16790816
[Journal Article] IFN-beta down-regulated the expression of DNA-repair gene. MGMT, and sensitizes resistant glioma cells to temozolomide.2005
- Author(s)
  Natsume Atsushi
- Journal Title
  
  Cancer Research 65
  
  Pages: 7573-7579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591438
[Patent] 生体分子の抽出方法2021
- Inventor(s)
  安井隆雄, 馬場嘉信, 篠田渉, 夏目敦至
- Industrial Property Rights Holder
  安井隆雄, 馬場嘉信, 篠田渉, 夏目敦至
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K21124
[Patent] セルフリーＤＮＡの抽出方法2020
- Inventor(s)
  安井隆雄, 馬場嘉信, 篠田渉, 夏目敦至
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-157294
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K21124
[Patent] 脳腫瘍を検査する方法2019
- Inventor(s)
  夏目敦至、安井隆雄、馬場嘉信
- Industrial Property Rights Holder
  夏目敦至、安井隆雄、馬場嘉信
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-177615
- Filing Date
  2019
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Urine-based genetic diagnosis of brain tumors.2023
- Author(s)
  Atsushi NATSUME, Takao YASUI, Yoshinobu BABA
- Organizer
  FIBER International Summit for Nucleic Acids 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03789
[Presentation] Urine-based genetic diagnosis of brain tumors2023
- Author(s)
  Atsushi NATSUME, Takao YASUI, Yoshinobu BABA
- Organizer
  第61回日本癌治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03789
[Presentation] DNA/RNAを移動する電子速度の測定によるIDH1変異の検出2023
- Author(s)
  夏目敦至、Fun Shuya, 平野雅規、高山和也、橋本克訓、丸山　厚、藤塚　守
- Organizer
  第41回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-20H03789
[Presentation] Impact of molecular-genetic crowding on clonal evolution of glioma2021
- Author(s)
  Atsushi Natsume
- Organizer
  World Federation of Neuro-Oncology Societies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] 次現世代における成人脳腫瘍の診断と治療2021
- Author(s)
  夏目敦至
- Organizer
  第32回日本脳腫瘍学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] 脳腫瘍におけるゲノム医療・遺伝子パネル検査2021
- Author(s)
  夏目敦至
- Organizer
  第62回日本神経病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] 脊髄損傷後の内在性幹細胞への神経転写因子導入による神経再生治療2021
- Author(s)
  福岡俊樹、加藤彰、粟屋尭之、西村由介、夏目敦至
- Organizer
  第36回脊髄外科学会　学術委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-19K09453
[Presentation] Neurod4導入マウスにおける脊髄損傷語の神経再生2019
- Author(s)
  粟屋尭之,夏目敦至,西村由介,江口馨,福岡俊樹,永島吉孝,若林俊彦
- Organizer
  第34回日本脊髄外科学会
- Data Source
  KAKENHI-PROJECT-19K09453
[Presentation] Neurod4 at the regenerative stage of X.laevis A promising transcription factor to promote functional recovery following spinal cord injury2019
- Author(s)
  Toshiki Fukuoka, Yusuke Nishimura, Atsushi Natsume
- Organizer
  13th Anniversary International Symposium on Nnanomedicine(ISNM2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09453
[Presentation] Mathematical prediction for precision medicine of CNS glial tumors2019
- Author(s)
  Kosuke Aoki（17人中1番目）, Atsushi Natsume (演者：17人中17番目）
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] immune-cold”と言われる脳腫瘍に対する免疫治療を考える2019
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第５回名古屋大学がん免疫フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Phase I study of a brain penetrant mutant IDH1 inhibitor DS-1001b in patients with recurrent or progressive IDH1 mutant gliomas2019
- Author(s)
  Atsushi Natsume（発表者）, Hiroshi Tsubouchi（17人中17番目）
- Organizer
  ASCO
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Neurofibromatosis 1と神経膠腫のゲノム解明とNF1変異動物モデルの表現型2019
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第10回日本レックリングハウゼン病学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] immune-cold”と言われる脳腫瘍に対する免疫治療を考える2019
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第５回名古屋大学がん免疫フォーラ
- Invited
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] 診断困難な成人diffuse midline glioma, H3 K27M-mutantにおけるddPCRの有用性2019
- Author(s)
  前田紗知、大岡史治、平野雅規、青木恒介、竹内和人、本村和也、棚橋邦明、加藤彰、北野詳太郎、西川知秀、清水浩之、山口純矢、山﨑慎太郎、若林俊彦、夏目敦至
- Organizer
  第20回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09478
[Presentation] Molecular and genetic classification of brain tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  The WFNS Educational Course
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] 11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine2019
- Author(s)
  Kosuke Aoki（17人中1番目）, Atsushi Natsume (演者：17人中17番目）
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Phase I study of a brain penetrant mutant IDH1 inhibitor DS-1001b in patients with recurrent or progressive IDH1 mutant gliomas2019
- Author(s)
  Atsushi Natsume（発表者）, Hiroshi Tsubouchi（17人中17番目）
- Organizer
  ASCO2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] Neural regeneration with Gene delivery by novel pseudo typed retrovirus2019
- Author(s)
  Takayuki Awaya, Akira Kato ,Toshiki Fukuoka, Yusuke Nishimura, Toshsihiko Wakabayashi, Atsushi Natsume
- Organizer
  第20回分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09453
[Presentation] Mathematical prediction for precision medicine of CNS glial tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  AACR-JCA joint meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] 脊髄損傷モデルマウスの内在性神経幹細胞に対する遺伝子導入と機能回復2019
- Author(s)
  粟屋尭之,加藤彰,福岡俊樹,西村由介,若林俊彦,夏目敦至
- Organizer
  第78回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-19K09453
[Presentation] Mathematical prediction for precision medicine of CNS glial tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  AACR-JCA joint meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Molecular and genetic classification of brain tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  The WFNS Educational Course
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] Brain functional mapping and awake craniotomy for brain tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  The WFNS Educational Course
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0228
[Presentation] Neurofibromatosis 1と神経膠腫のゲノム解明とNF1変異動物モデルの表現型2019
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第10回日本レックリングハウゼン病学
- Invited
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Brain functional mapping and awake craniotomy for brain tumors2019
- Author(s)
  Atsushi Natsume
- Organizer
  The WFNS Educational Course
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] 悪性神経膠腫薬物療法における現状の今後の展望2018
- Author(s)
  夏目敦至、青木恒介、若林俊彦
- Organizer
  第10回東海脳腫瘍手術手技研究会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Lower-grade gliomaの遺伝子不均一性獲得の数理シミュレーション2018
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  日本脳腫瘍学会
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] State of art treatment for brain cancer using single cell atlas and artificial intelligence2018
- Author(s)
  Atsushi Natsume
- Organizer
  日越国交45周年記念祝賀会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] グリオーマでのクローン進化を数理モデル2018
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第10回がんゲノム・エピゲノム、数理統計解析についての勉強会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] ゲノム時代におけるグリオーマの治療戦略2018
- Author(s)
  夏目敦至
- Organizer
  第22回北海道脳腫瘍懇話会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] ゲノム時代におけるグリオーマの治療戦略ー手術、化学療法、放射線治療のタイミングー2018
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  Glioma Update Seminar
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] State of art treatment for brain cancer using single cell atlas and artificial intelligence2018
- Author(s)
  Atsushi Natsume
- Organizer
  日越国交45周年記念祝賀
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Genome-based Precision Medicine in Brain Tumors2018
- Author(s)
  Atsushi Natsume
- Organizer
  First Joint US-Japan Clinical Cancer Genomics and Personalized Medicine Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] ゲノム時代におけるグリオーマの治療戦略2018
- Author(s)
  夏目敦至
- Organizer
  第22回北海道脳腫瘍懇話会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] シングル細胞レベルのCell AtlasとAIを用いた脳腫瘍治療への展望2018
- Author(s)
  夏目敦至、若林俊彦
- Organizer
  日本脳神経外科コングレス2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] 日本発のキメラ抗原受容体遺伝子導入T細胞の臨床治験2018
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第77回日本脳神経脳神経外科学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Genome-based Precision Medicine in Brain Tumors2018
- Author(s)
  Atsushi Natsume
- Organizer
  First Joint US-Japan Clinical Cancer Genomics and Personalized Medicine Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] Molecular classificationn of gliomas2018
- Author(s)
  Atsushi Natsume
- Organizer
  International Society of Brain Tumor Pathology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] グリオーマでのクローン進化を数理モデル2018
- Author(s)
  夏目敦至、大岡史治、若林俊彦、近藤　豊
- Organizer
  第10回がんゲノム・エピゲノム、数理統計解析についての勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Mutational landscape and clonal architecture2017
- Author(s)
  Atsushi Natsume
- Organizer
  Chemistry of Molecular Crowding
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Mutational landscape and clonal architecture2017
- Author(s)
  Atsushi Natsume
- Organizer
  Chemistry of Molecular Crowding
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06356
[Presentation] 脳腫瘍　迅速診断遺伝子検査の意義2016
- Author(s)
  夏目敦至
- Organizer
  第105回日本病理学会総会
- Place of Presentation
  仙台、宮城県
- Year and Date
  2016-05-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] 脳腫瘍の網羅的ゲノム解析と個別化診断医療2016
- Author(s)
  夏目敦至
- Organizer
  第３回バイオセンシングコンソーシアム
- Place of Presentation
  東京
- Year and Date
  2016-05-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Notchシグナルにより誘導される長鎖非翻訳RNA TUG1を標的としたグリオーマ治療薬の開発に関する研究2016
- Author(s)
  勝島啓佑、夏目敦至、大岡史治、新城恵子、市村典久、畑中彬良、柴田龍弘、宮田完二郎、片岡一則、近藤　豊
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜 (神奈川件横浜市)
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-25290048
[Presentation] Genetic biomarkers to predict prognosis and kinetics of clonal evolution by mathematical computational modeling in low-grade glioma2016
- Author(s)
  Atsushi Natsume
- Organizer
  International Brain Tumor Research and Therapy
- Place of Presentation
  那覇、沖縄県
- Year and Date
  2016-04-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] ゲノムから見た低悪性度神経膠腫の手術のdecision making2016
- Author(s)
  夏目敦至
- Organizer
  脳腫瘍治療セミナー
- Place of Presentation
  東京
- Year and Date
  2016-06-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] グリオーマの遺伝生物学と最新の免疫治療の展望2016
- Author(s)
  夏目敦至
- Organizer
  第36回日本脳神経外科コングレス総会
- Place of Presentation
  大阪
- Year and Date
  2016-05-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05436
[Presentation] Loss of b-series gangliosides attenuates glioma development and expansion.2016
- Author(s)
  Ohkawa Y, Momota H, Kato A, Esaki N, Chou B, Takano M, Bhuiyan RH, Furukawa K, Natsume A, Wakabayashi T, Furukawa K.
- Organizer
  The 3rd International Symposium on Glycol-Neuroscience
- Place of Presentation
  淡路夢舞台国際会議場、兵庫県淡路市
- Year and Date
  2016-01-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19073
[Presentation] Identification of GD3-regulated genes in GD3-expressing gliomas.2016
- Author(s)
  Ohkawa Y, Noda S, Momota H, Kato A, Chou B, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T and Furukawa K.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K19073
[Presentation] グリオーマにおいてガングリオシドGD3はPDGFRαの発現を誘導する2016
- Author(s)
  大川祐樹、百田洋之、加藤彰、橋本登、古川圭子、大海雄介、夏目敦至、若林俊彦、古川鋼一
- Organizer
  第35回日本糖質学会年会
- Place of Presentation
  高知県高知市文化プラザかるぽーと
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-15K19073
[Presentation] Ganglioside GD3 promotes development and invasion of gliomas.2015
- Author(s)
  Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Furukawa K, Ohmi Y, Natsume A, Wakabayashi T, Furukawa K.
- Organizer
  第27回日本糖質学会
- Place of Presentation
  東京大学安田講堂、東京都文京区
- Year and Date
  2015-07-31
- Data Source
  KAKENHI-PROJECT-15K19073
[Presentation] Expression of gangliosides GD3 promotes development and expansion of gliomas in glioma model mice.2015
- Author(s)
  Ohkawa Y, Momota H, Kato A, Hashimoto N, Tsuda Y, Esaki N, Furukawa K, Natsume A, Wakabayashi T, Furukawa K.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場、愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K19073
[Presentation] 日本におけるTSC標準治療を目指して2014
- Author(s)
  夏目敦至
- Organizer
  TSC Days Japan 2014
- Place of Presentation
  福岡県福岡市ホテル日航
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-24390341
[Presentation] Intraoperative image-guided glioma surgery2014
- Author(s)
  T Wakabayashi, A Natsume, K Motomura, M Fujii, K Mori, Y Hayashi
- Organizer
  The 4th Russia- Japan Neurosurgical Symposium
- Place of Presentation
  広島県、広島市、（グランドプリンスホテル広島
- Year and Date
  2014-10-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249073
[Presentation] 網羅的(エピ)ゲノム解析に基づく治療戦略2014
- Author(s)
  夏目敦至
- Organizer
  癌治療学会
- Place of Presentation
  神奈川県横浜市横浜パシフィコ
- Year and Date
  2014-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-24390341
[Presentation] Skull base brain tumor surgery navigation system based on updating preoperative images using positional information of surgical tools2014
- Author(s)
  T Wakabayashi, A Natsume, K Motomura, M Fujii, K Mori, Y Hayashi
- Organizer
  International conference on brain tumor research and therapy (ICBTRT)
- Place of Presentation
  ナイアガラフォールズ、カナダ
- Year and Date
  2014-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24249073
[Presentation] テモダールの陰翳礼賛から学ぶ悪性神経膠腫の神秘2014
- Author(s)
  夏目敦至
- Organizer
  第32回日本脳腫瘍学会
- Place of Presentation
  千葉県浦安市シェラトングランデ
- Year and Date
  2014-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-24390341
[Presentation] EGFRｖIII特異的キメラ抗原レセプターを発現するT細胞へのmiR-17-92遺伝子導入はマウスGBMモデルにおいて抗腫瘍活性を増強させる2013
- Author(s)
  大野真佐輔大栗敬幸小坂朱棚橋邦明若林俊彦夏目敦至岡田秀穂
- Organizer
  第72回日本脳神経外科学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25861270
[Presentation] GBMに対する化学療法による低免疫環境に耐性を持つ遺伝子改変T細胞療法の開発2013
- Author(s)
  大野真佐輔大栗敬幸小坂朱棚橋邦明若林俊彦夏目敦至岡田秀穂
- Organizer
  第31回日本脳腫瘍学会学術集会
- Place of Presentation
  宮崎県宮崎市山崎町浜山フェニックス・シーガイア・リゾート
- Data Source
  KAKENHI-PROJECT-25861270
[Presentation] Immunohistochemical analysis-based subclassification of gliomas with integrated genomic and epigenetic profile2012
- Author(s)
  Natsume A
- Organizer
  Asian Society of Neuro-Oncology
- Place of Presentation
  台北、台湾(招待講演)
- Year and Date
  2012-04-21
- Data Source
  KAKENHI-PROJECT-24390341
[Presentation] Current trends in chemotherapy for glioblastoma multiforme2011
- Author(s)
  夏目敦至
- Organizer
  奈良脳神経外科セミナー
- Place of Presentation
  難波、大阪(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 悪性脳腫瘍のエピジェネティクス異常2011
- Author(s)
  夏目敦至
- Organizer
  神奈川脳神経外科セミナー
- Place of Presentation
  神奈川県(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] Epigenetic alteration in glioma2011
- Author(s)
  夏目敦至
- Organizer
  Korea Brain Tumor Society Meeting
- Place of Presentation
  ソウル、韓国(招待講演)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] Current trends in chemotherapy for glioblastoma multiforme2011
- Author(s)
  夏目敦至
- Organizer
  奈良脳神経外科セミナー
- Place of Presentation
  難波、大阪(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] Gliomaにおける治療戦略2011
- Author(s)
  夏目敦至
- Organizer
  鹿児島脳神経外科セミナー
- Place of Presentation
  鹿児島(招待講演)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] Regulation of heterogeneity by Epigenetic modifications in GBM stem cells2011
- Author(s)
  Natsume, A
- Organizer
  IARC Seminar
- Place of Presentation
  Lyon, France
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Epigenetic alteration in glioma2011
- Author(s)
  夏目敦至
- Organizer
  Korea Brain Tumor Society Meeting
- Place of Presentation
  ソウル、韓国(招待講演)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 悪性脳腫瘍のエピジェネティクス異常2011
- Author(s)
  夏目敦至
- Organizer
  神奈川脳神経外科セミナー
- Place of Presentation
  神奈川県(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Gliomaにおける治療戦略2011
- Author(s)
  夏目敦至
- Organizer
  鹿児島脳神経外科セミナー
- Place of Presentation
  鹿児島(招待講演)
- Year and Date
  2011-11-04
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 髄膜腫のエピゲノム解析2010
- Author(s)
  岸田悠吾, 夏目敦至, 近藤豊, 齋藤清, 若林俊彦
- Organizer
  第69回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] エピゲノムの見地からみた髄膜腫の再分類2010
- Author(s)
  岸田悠吾, 夏目敦至, 近藤豊, 齋藤清, 若林俊彦
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] テモダールをはじめとした化学療法の最新の治療成績と今後の展望2010
- Author(s)
  若林俊彦、夏目敦至、藤井正純、渋井壮一郎
- Organizer
  第30回日本脳神経外科コングレス総会
- Place of Presentation
  横浜
- Year and Date
  2010-05-07
- Data Source
  KAKENHI-PROJECT-21390409
[Presentation] エピゲノムの見地からみた髄膜腫の再分類2010
- Author(s)
  岸田悠吾, 夏目敦至, 近藤豊, 齋藤清, 若林俊彦
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] Immuno-therepay using retrovirally engineered T cells expressing chimeric antigen receptors specific to glioma-associated antigens2010
- Author(s)
  Natsume A
- Organizer
  International Society of Cell Therapy
- Place of Presentation
  Miyazaki, Japan
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 初発膠芽腫に対するIFN-b+テモダール併用化学放射線療法のランダム化第2相試験2010
- Author(s)
  若林俊彦、夏目敦至、藤井正純、渋井壮一郎
- Organizer
  第69回日本脳神経外科学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21390409
[Presentation] 脳腫瘍の最新アトラス2010
- Author(s)
  夏目敦至
- Organizer
  静岡がんセンターセミナー
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Immuno-therepay usingretrovirally engineered T cells expressing chimeric antigen receptors specific to glioma-associated antigens2010
- Author(s)
  Natsume, A
- Organizer
  International Society of Cell Therapy
- Place of Presentation
  Miyazaki, Japan
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Regulation of heterogeneity by Epigenetic modifications in GBM stem cells2010
- Author(s)
  Natsume A
- Organizer
  Memorial Sloan Kettering Seminar
- Place of Presentation
  New York, USA
- Year and Date
  2010-06-02
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 髄膜腫のエピゲノム解析2010
- Author(s)
  岸田悠吾, 夏目敦至, 近藤豊, 齋藤清, 若林俊彦
- Organizer
  第69回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] 髄膜腫のエピゲノム解析2010
- Author(s)
  岸田悠吾, 夏目敦至, 近藤豊, 齋藤清, 若林俊彦
- Organizer
  第69回日本分子脳神経外科学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] A clinical trial of interleukin-13 receptor alpha 2 peptide-pulsed DC vaccine for malignant gliomas2010
- Author(s)
  夏目敦至
- Organizer
  World Congress of Vaccine
- Place of Presentation
  Beijing, China
- Year and Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] A Multicenter Phase I Trial of Combination Therapy with Interferon-β and Temozolomide for High-grade Gliomas (INTEGRA study) : The Final Report2010
- Author(s)
  Natsume A
- Organizer
  9^<th> annual meeting of Asian Clinical Oncology Society
- Place of Presentation
  Gifu, Japan
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 初発膠芽腫に対するIFN-β+テモダール併用療法の retrospective study2009
- Author(s)
  夏目敦至
- Organizer
  東海脳腫瘍セミナー
- Place of Presentation
  名古屋
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Polycomb-based epigenetic therapy targeting brain tumor-initiating cells2009
- Author(s)
  夏目敦至
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] 膠芽腫の組織不均一性を制御するエピジェネティクス機構の解明と小分子化合物の開発2009
- Author(s)
  夏目敦至
- Organizer
  第27回日本脳腫瘍学会
- Place of Presentation
  大阪
- Year and Date
  2009-11-08
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Epigenetic plasticity in gliomas2009
- Author(s)
  夏目敦至
- Organizer
  Seminar in Seoul National University
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] グリオーマ幹細胞の多分化能を制御するポリコームタンパク群の分子標的治療薬の開発2009
- Author(s)
  夏目敦至
- Organizer
  第68回日本脳神経外科学会学術総会
- Place of Presentation
  東京
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Epigenetic plasticity in gliomas2009
- Author(s)
  夏目敦至
- Organizer
  グローバルCOE国内シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Epigenetic plasticity in gliomas2009
- Author(s)
  夏目敦至
- Organizer
  Aspen symposium
- Place of Presentation
  DA, USA
- Year and Date
  2009-08-09
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Epigenetic plasticity in gliomas2009
- Author(s)
  夏目敦至
- Organizer
  Seminar in University of California San Francisco
- Place of Presentation
  CA, USA
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21390408
[Presentation] Characteristics of AtypicalMeningiomas2008
- Author(s)
  Natsume,A
- Organizer
  6th International Congress on Meningiomas and Cerebral Venous System
- Place of Presentation
  Boston, MA, USA
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] Genetic characteristics of malignant meningiomas.2008
- Author(s)
  夏目敦至, 齋藤清, et al.
- Organizer
  6th International Congress on Meningiomas and Cerebral Venous System
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20591710
[Presentation] NEURAL STEM CELLS TRANSDUCED WITH THE IFN-beta AND CYTOSINE DEAMINASE GENES ENHANCE BYSTANDER EFFECT IN EXPERIMENTAL GLIOMAS2008
- Author(s)
  Natsume, A
- Organizer
  The 14th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] ポストゲノム時代のエピジェネティクス解析 : MGMT遺伝子メチル化の定量の試み2008
- Author(s)
  夏目敦至
- Organizer
  第26回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] GLOBAL ANALYSES OF POLYCOMB MEDIATED TRANSCRPTIONALREPRESSION AND DNA METHYLATION TARGETS IN BRAIN TUMOR STEM CELLS2008
- Author(s)
  Natsume, A
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] A JAPANESE MULTICENTER CLINICAL TRIAL OF INTERFERON-B AND TEMOZOLOMIDE COMBINATION THERAPY FOR HIGH-GRADE GLIOMAS : FROM BENCH TO BEDSIDE2008
- Author(s)
  Natsume, A
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] TARGETING OF GLIOMA CELLS EXPRESSING THE EGFR TYPE 3 VARIANT USING GENETICALLY ENGINEERED T-CELLS2008
- Author(s)
  Natsume, A
- Organizer
  The 14th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] THE DNA DEMETHYLATING AGENT 5- AZA-2-DEOXYCYTIDINE INDUCES THE EXPRESSION OF CANCER-TESTIS ANTIGENS IN HUMAN GLIOMAS : EPIGENETIC TAEGET FOR TUMOR IMMUNOTHERAPY.2008
- Author(s)
  Natsume A
- Organizer
  The 17th International Conference on Brain Tum or Research and Therapy.
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] Characteristics of AtjnpicalMenmgiomas.2008
- Author(s)
  Natsume A
- Organizer
  6th International Congress on Meningiomas and Cerebral Venous System.
- Place of Presentation
  Boston, MA< USA
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] グリオーマ幹細胞に対する分子標的治療の開発2008
- Author(s)
  夏目敦至
- Organizer
  第67回日本脳神経外科学会総会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] グリオーマ幹細胞の網羅的エピジェネティクス解析2008
- Author(s)
  夏目敦至
- Organizer
  第9回日本分子脳神経外科学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] 脳腫瘍治療の最近の進歩2008
- Author(s)
  夏目敦至
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] THE DNA DEMETHYLATING AGENT 5- AZA-2-DEOXYCYTIDINE INDUCES THE EXPRESSION OF CANCER-TESTIS ANTIGENS IN HUMAN GLIOMAS : EPIGENETIC TARGET FOR TUMOR IMMUNOTHERAPY2008
- Author(s)
  Natsume, A
- Organizer
  The 17th International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] A JAPANESE MULTICENTER CLINICAL TRIAL OF INTERFERON-B AND TEMOZOLOMIDE COMBINATION THERAPY FOR HIGH-GRADE GLIOMAS : FROM BENCH TO BEDSIDE.2008
- Author(s)
  Natsume A
- Organizer
  The 17th International Conference on Brain Tum or Research and Therapy.
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] 脳腫瘍幹細胞の起源 : エピジェネティクス解析とポリコーム蛋白標的治療の開発2008
- Author(s)
  夏目敦至
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] GLOBAL ANALYSES OF POLYCOMB MEDIATED TRANSCRPTIONALREPRESSION AND DNA METHYLATION TARGETS IN BRAIN TUMOR STEM CELLS.2008
- Author(s)
  Natsume A
- Organizer
  The 17th International Conference on Brain Tum or Research and Therapy.
- Place of Presentation
  Hakodate, Japan
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] Epigenetic target for cancer-testis antigen-based tumor immunotherapy2007
- Author(s)
  夏目敦至
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] グリオーマ幹細胞の網羅的エピジェネティクス解析2007
- Author(s)
  夏目敦至
- Organizer
  第66回日本脳神経外科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] グリオーマ幹細胞の網羅的エピジェネティクス解析2007
- Author(s)
  夏目敦至
- Organizer
  第25回日本脳腫瘍学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] バルプロ酸とDNAメチル化酵素阻害薬による2007
- Author(s)
  夏目敦至
- Organizer
  グリオーマの癌精巣抗原遺伝子のクロマチン構造変化第25回日本脳腫瘍学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19591669
[Presentation] 悪性脳腫瘍細胞のヒエラルキーとエピゲノム変化
- Author(s)
  夏目敦至
- Organizer
  脳腫瘍学術講演会
- Place of Presentation
  リーガロイヤルホテル（大阪）
- Invited
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] 免役シナプスを強化する lenalidomide と EGFRvIII キメラ抗原受容体発現 T 細胞の併用効果
- Author(s)
  倉光俊一郎、夏目敦至、大野真佐輔、椎名諭、若林俊彦
- Organizer
  第32回日本脳腫瘍学会学術集会
- Place of Presentation
  千葉県浦安市舞浜
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-25861270
[Presentation] 癌が運動野、言語野に近くに転移したらどうしますか
- Author(s)
  夏目敦至
- Organizer
  癌と中枢神経合併症フォーラム2013
- Place of Presentation
  日本大学国際関係部（三島市）
- Invited
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] GBMに対するPodoplanin特異的キメラ抗原受容体を発現するT細胞の抗腫瘍効果の検討
- Author(s)
  椎名諭、夏目敦至、大野真佐輔、倉光俊一郎、加藤幸成、Darell D. Bigner、若林俊彦
- Organizer
  日本脳神経外科学会第73回学術総会
- Place of Presentation
  東京都港区高輪
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25861270
[Presentation] Podoplanin 特異的キメラ抗原受容体を発現する T 細胞の GBM に対する抗腫瘍効果の検討
- Author(s)
  椎名諭、夏目敦至、大野真佐輔、倉光俊一郎、加藤幸成、Darell D. Bigner、若林俊彦
- Organizer
  第32回日本脳腫瘍学会学術集会
- Place of Presentation
  千葉県浦安市舞浜
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-25861270
[Presentation] Epigenetic plasticity in cancer-intiating cells
- Author(s)
  Natsume A
- Organizer
  Minisymposium Neuroscience
- Place of Presentation
  ウィーン（オーストリア）
- Data Source
  KAKENHI-PLANNED-23107010
[Presentation] Advanced Multimodal Treatment Strategies for Malignant Gliomas
- Author(s)
  若林俊彦　藤井正純　夏目敦至
- Organizer
  The 15th World Congress of Neurosurgery
- Place of Presentation
  Seoul, Korea
- Year and Date
  2013-09-09 – 2013-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-24249073
[Presentation] IDH1変異のある悪性脳腫瘍のメタボローム解析
- Author(s)
  夏目敦至
- Organizer
  がんと代謝シンポジウム2013
- Place of Presentation
  慶応大学（東京）
- Invited
- Data Source
  KAKENHI-PLANNED-23107010
[]
[]

1. WAKABAYASHI Toshihiko (50220835)

# of Collaborated Projects: 6 results

# of Collaborated Products: 77 results
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# of Collaborated Products: 4 results
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27. SENGA Takeshi (80419431)

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34. Katsushima Keisuke (00754053)

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35. OHKAWA Yuki (40723896)

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# of Collaborated Projects: 1 results

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50. 三好大輔 (50388758)

# of Collaborated Projects: 1 results

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51. KISHIDA Yugo

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
52. OKADA Hideho

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
53. KURAMITSU Shunichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
54. SHIINA Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
55. HASHIMOTO Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
56. NAKAMURA Hideo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
57. HIDE Takuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. FUJII Yukihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. OHMI Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. KIJIMA Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
61. IWADATE Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
62. 本村和也

# of Collaborated Projects: 0 results

# of Collaborated Products: 11 results
63. 松井佑介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
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# of Collaborated Products: 1 results
73. 川井清彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
74. 奥田武司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NATSUME Atsushi 夏目 敦至

NATSUNE Atsushi 夏目 敦至

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The regulation of gene expression by targeting G4 quadriplex in brain tumorsPrincipal Investigator

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The evolutional trajection and precision-medicine to gliomasPrincipal Investigator

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Novel treatment strategy targeting neoantigen induced by epigenetic alterations in malignant glioma formationPrincipal Investigator

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Identification of molecules targeting cancers and neurons based on molecular tracingPrincipal Investigator

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Super-enhancer and dynamic chromatine remodeling in gliomagenesisPrincipal Investigator

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NATSUME Atsushi 夏目敦至

NATSUNE Atsushi 夏目敦至