• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Kagamu Hiroshi  各務 博

ORCIDConnect your ORCID iD *help
… Alternative Names

KAGAMU Hiroshi  各務 博

Less
Researcher Number 30418686
Other IDs
Affiliation (Current) 2025: 埼玉医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2025: 埼玉医科大学, 医学部, 教授
2014: 新潟大学, 医歯学系, 准教授
2010 – 2013: Niigata University, 医歯学系, 講師
2012: 新潟大学, 医歯学系, 助教
2009: 新潟大学, 医歯学総合病院, 助教 … More
2007 – 2009: Niigata University, Institute of Medicine and Dentistry, Assistant Professor
2007: 新潟大学, 医歯学総合病院, 助教
2005 – 2006: 新潟大学, 医歯学総合病院, 助手 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / Infectious disease medicine / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
小細胞肺癌 / DDX3X / 制御性T細胞 / CD4 T細胞 / 癌幹細胞 / 肺癌 / PD-1 / 抗CTLA-4抗体 / PD-1阻害薬 / 免疫プレシジョンメディシン … More / mass cytometry / scRNAseq / がん免疫サイクル / 術後無再発生存 / HEV / 抗腫瘍CD4+ T細胞 / Th7R / CD4+ T細胞 / 抗腫瘍T細胞免疫 / CD4T細胞 / 抗PD-1抗体 / T細胞免疫モニタリング / CD4 T細胞エフェクター / 放射線治療 / CD62LlowCD4 T細胞 / CD62Llow CD4 T細胞 / 末梢血T細胞クラスター / 免疫チェックポイント阻害薬治療 / Treg / CD62L / 末梢血バイオマーカー / 免疫チェックポイント阻害薬 / antitumor effector CD4 T cell / regulatory T cell / small cell lung cancer / 抗腫瘍エフェクターCD4T細胞 / 抗腫瘍エフェクターCD4 T細胞 / 抗腫瘍免疫 / TelomeScan / 循環腫瘍細胞 / β-catenin / VEGFR / beta-catenin / EGFR / EGFR遺伝子変異陽性肺癌 / VEGF / Wnt/β-catenin / 国際情報交流 / 国債情報交換 / CD4+ T細胞 / メラノーマ / 抗腫瘍免疫療法 / Th17 / その他 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患 … More
Except Principal Investigator
肺癌 / 免疫関連有害事象 / 非小細胞肺癌 / 免疫チェックポイント阻害薬 / T細胞 / CD137 / CD40 / DR5 / lymphodepletion / 腫瘍免疫 / 腫瘍免疫療法 / 抑制性T細胞 / CXCL13 / 副作用 / irAE / 抗CTLA-4抗体 / PD-1阻害薬 / 胸部悪性腫瘍 / 肺臓炎 / 微生物 / 感染症 / 多剤耐性結核 / ナノポア型シーケンサー / 下気道細菌叢 / ストレプトコッカス / 核酸精製 / 非結核性抗酸菌 / 微生物叢 / MinION / ナノポアシーケンサー / 免疫学 / 癌 / T細胞免疫 / 抗がん剤治療 / 放射線治療 / 抗癌剤 / エフェクターT細胞 / 免疫チェックポイント / PFS / 末梢血単核球 / 小細胞肺癌 / 抗PD-L1抗体 / 間質性肺疾患 / 抗PD-L1抗体 / ペムブロリズマブ / ニボルマブ / 薬剤性肺障害 / 抗PD-1抗体 / adoptive immunotherapy / Adoptive immunotherapy / PD-L1 / PD-1 / 免疫療法 / Dendritic cell / RNA導入 / 防御免疫 / 抗CD40抗体 / CD62 / 制御性T細胞 / 皮下腫瘍モデル / 樹状細胞 / regulatory T cells / tumor immunotherapy / regulatory T cell / 細胞療法 / lung cancer / Regulatory T cells / Tumor immunotherapy / 放射線療法 / 抗腫瘍免疫療法 / MDSC / 化学療法 / 非特異的肺疾患癌 / その他 / 呼吸器感染症 / 肺線維症 / 非閉塞性肺疾患癌 / 担癌患者 / 健常者 / 抗VEGF抗体 / 抗サイトカイン抗体 / VEGF / インターロイキン / TNF-α / GM-CSF / サイトカイン / 自己抗体 Less
  • Research Projects

    (18 results)
  • Research Products

    (163 results)
  • Co-Researchers

    (25 People)
  •  新規CD4陽性T細胞クラスター養子免疫療法によるtertiary lymphoid structureの誘導

    • Principal Investigator
      渡部 聡
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Niigata University
  •  PBMCを用いたirAE発症予測システムの開発

    • Principal Investigator
      山口 央
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Saitama Medical University
  •  Development of immunoprecision medicine for lung cancer using peripheral bloodPrincipal Investigator

    • Principal Investigator
      各務 博
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Saitama Medical University
  •  Elucidation of immunological mechanism of lung injury and corresponding antigen by anti-PD-1 antibody

    • Principal Investigator
      Yamaguchi Ou
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Saitama Medical University
  •  Study on a type of chemotherapy regimen that induces immune status into response pattern for anti-PD-1 antibody in small lung cancer patients

    • Principal Investigator
      Nishihara Fuyumi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Saitama Medical University
  •  Comprehensive analysis of the microflora using a novel portable sequencer MinION

    • Principal Investigator
      Takuya Maeda
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Infectious disease medicine
    • Research Institution
      Saitama Medical University
  •  Development of Breakthrough Immune Checkpoint Inhibitory Therapy Using Novel Immunological BiomarkersPrincipal Investigator

    • Principal Investigator
      KAGAMU HIROSHI
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Saitama Medical University
  •  Novel antitumor immunotherapy via immune reconstitution after chemotherapy for advanced lung cancer

    • Principal Investigator
      Watanabe Satoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Molecular targeted medicine to inhibit cancer stemnessPrincipal Investigator

    • Principal Investigator
      Kagamu Hiroshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Saitama Medical University
      Niigata University
  •  A novel anti tumor immunotherapy to eliminate circulating tumor cells of SCLCPrincipal Investigator

    • Principal Investigator
      Kagamu Hiroshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Saitama Medical University
      Niigata University
  •  Novel tumor immunotharapy for advanced lung cancer using homeostatic reconstitution of antitumor immunity

    • Principal Investigator
      WATANABE Satoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Anti-tumor immunotherapy targeting a cancer stem cell-specific protein for small cell lung cancerPrincipal Investigator

    • Principal Investigator
      KAGAMU HIROSHI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Effective cancer immunotherapy for advanced lung cancer during homeostatic proliferation

    • Principal Investigator
      WATANABE Satoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Antitumor immunotherapy for small cell lung cancer with Th17 inductionPrincipal Investigator

    • Principal Investigator
      KAGAMU Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Treatment of lung cancer with the regulation of anti-VEGF auto-antibody

    • Principal Investigator
      YOSHIZAWA Hirohisa
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  感染・炎症における生体の恒常性維持に関する新概念の確立

    • Principal Investigator
      NAKATA Koh
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Niigata University
  •  A novel antitumor immunotherapy to break the tolerance induced in small cell lung cancer patientsPrincipal Investigator

    • Principal Investigator
      KAGAMU Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University
  •  Application of allograft rejection for lung cancer treatment

    • Principal Investigator
      YOSHIZAWA Hirohisa
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Niigata University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book Patent

  • [Book] あたらしい肺癌現場診断学2017

    • Author(s)
      各務博
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Book] 呼吸器内科2017

    • Author(s)
      各務博
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Book] Molecular Targeted Therapy of Lung Cancer2016

    • Author(s)
      Hiroshi Kagamu, Kunihiko Kobayashi
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Book] 急性腎不全・AKIハンドブック(抗がん剤による急性腎不全)2010

    • Author(s)
      各務博、西慎一
    • Total Pages
      5
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] A Th1-like CD4+ T-cell Cluster That Predicts Disease-free Survival in Early-stage Lung Cancer2023

    • Author(s)
      Yanagihara Akitoshi、Yamasaki Satoshi、Hashimoto Kosuke、Taguchi Ryo、Umesaki Tetsuya、Imai Hisao、Kaira Kyoichi、Nitanda Hiroyuki、Sakaguchi Hirozo、Ishida Hironori、Kobayashi Kunihiko、Horimoto Katsuhisa、Kagamu Hiroshi
    • Journal Title

      Cancer Research Communications

      Volume: 3 Issue: 7 Pages: 1277-1285

    • DOI

      10.1158/2767-9764.crc-23-0167

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-23K24341
  • [Journal Article] Clinicopathological impact of VEGFR2 and VEGF-C in patients with EGFR-major mutant NSCLC receiving osimertinib2023

    • Author(s)
      Kyoichi Kaira, Hisao Imai, Atsuto Mouri, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Ou Yamaguchi, Kunihiko Kobayashi, Tomonori Kawasaki, Masanori Yasuda, Hiroshi Kagamu
    • Journal Title

      Thoracic Cancer

      Volume: 14 Issue: 29 Pages: 2950-2961

    • DOI

      10.1111/1759-7714.15082

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06910, KAKENHI-PROJECT-23K24341
  • [Journal Article] Prognostic significance of tumor infiltrating lymphocytes on first-line pembrolizumab efficacy in advanced non-small cell lung cancer2023

    • Author(s)
      Kaira K, Yamaguchi O, Kawasaki T, Hashimoto K, Miura Y, Shiono A, Mouri A, Imai H, Kobayashi K, Yasuda M, Kagamu H
    • Journal Title

      Discov Oncol

      Volume: 14 Issue: 1 Pages: 6-6

    • DOI

      10.1007/s12672-023-00615-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08118, KAKENHI-PROJECT-21K06910, KAKENHI-PROJECT-23K24341
  • [Journal Article] Predictive significance of circulating tumor DNA against patients with T790M-positive EGFR-mutant NSCLC receiving osimertinib2023

    • Author(s)
      Yamaguchi Ou、Kasahara Norimitsu、Soda Hiroshi、Imai Hisao、Naruse Ichiro、Yamaguchi Hiroyuki、Itai Miki、Taguchi Kohei、Uchida Megumi、Sunaga Noriaki、Maeno Toshitaka、Minato Koichi、Tomono Hiromi、Ogawara Daiki、Mukae Hiroshi、Miura Yu、Shiono Ayako、Mouri Atsuto、Kagamu Hiroshi、Kaira Kyoichi
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 20848-20848

    • DOI

      10.1038/s41598-023-48210-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Journal Article] Comparative analysis of different response criteria at early phase after PD-1 blockade in non-small lung cancer2023

    • Author(s)
      Kaira K, Yamaguchi O, Naruse I, Umeda Y, Honda T, Watanabe S, Ichikawa K, Yanagisawa S, Kasahara N, Higuchi T, Hashimoto K, Miura Y, Shiono A, Mouri A, Imai H, Iizuka K, Ishizuka T, Minato K, Suda S, Kagamu H, Mori K, Seki N, Kuji I.
    • Journal Title

      Cancer Imaging

      Volume: 23 Issue: 1 Pages: 23-23

    • DOI

      10.1186/s40644-023-00538-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08118, KAKENHI-PROJECT-23K24341
  • [Journal Article] Systemic CD4 Immunity and PD-L1/PD-1 Blockade Immunotherapy2022

    • Author(s)
      Escors David、Bocanegra Ana、Chocarro Luisa、Blanco Ester、Pieiro-Hermida Sergio、Garnica Maider、Fernandez-Rubio Leticia、Vera Ruth、Arasanz Hugo、Kochan Grazyna、Kagamu Hiroshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 21 Pages: 13241-13241

    • DOI

      10.3390/ijms232113241

    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Journal Article] Establishing a whole blood CD4+ T cell immunity measurement to predict response to anti-PD-12022

    • Author(s)
      Yamaguchi Ou、Atarashi Kazuyuki、Yoshimura Kenichi、Shiono Ayako、Mouri Atsuhito、Nishihara Fuyumi、Miura Yu、Hashimoto Kosuke、Miyamoto Yoshiaki、Uga Hitoshi、Seki Nobuo、Matsushima Tomoko、Kikukawa Norihiro、Kobayashi Kunihiko、Kaira Kyoichi、Kagamu Hiroshi
    • Journal Title

      BMC Cancer

      Volume: 22 Issue: 1 Pages: 1325-1325

    • DOI

      10.1186/s12885-022-10445-2

    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Journal Article] Single-Cell Analysis Reveals a CD4+ T-cell Cluster That Correlates with PD-1 Blockade Efficacy2022

    • Author(s)
      Kagamu H, Yamasaki S, Kitano S, Yamaguchi O, Mouri A, Shiono A, Nishihara F, Miura Y, Hashimoto K, Imai H, Kaira K, Kobayashi K, Kanai Y, Shibata T, Horimoto K
    • Journal Title

      Cancer Res

      Volume: 82 Issue: 24 Pages: 4641-4653

    • DOI

      10.1158/0008-5472.can-22-0112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08118, KAKENHI-PROJECT-23K24341
  • [Journal Article] Efficacy and Feasibility of Programmed Death-1/Programmed Death Ligand-1 Blockade Therapy in Non-Small Cell Lung Cancer Patients With High Antinuclear Antibody Titers.2021

    • Author(s)
      Mouri, A., K. Kaira, O. Yamaguchi, K. Hashimoto, Y. Miura, A. Shiono, S. Shinomiya, T. Akagami, H. Imai, K. Kobayashi, and H. Kagamu.
    • Journal Title

      Front Oncol.

      Volume: 11 Pages: 610952-610952

    • DOI

      10.3389/fonc.2021.610952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Effect of Systemic Steroid Use for Immune-Related Adverse Events in Patients with Non-Small Cell Lung Cancer Receiving PD-1 Blockade Drugs.2021

    • Author(s)
      Mouri, A., K. Kaira, O. Yamaguchi, K. Hashimoto, Y. Miura, A. Shiono, S. Shinomiya, H. Imai, K. Kobayashi, and H. Kagamu.
    • Journal Title

      J Clin Med.

      Volume: 10 Issue: 16 Pages: 3744-3744

    • DOI

      10.3390/jcm10163744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Pretreatment Glasgow prognostic score predicts survival among patients with high PD-L1 expression administered first-line pembrolizumab monotherapy for non-small cell lung cancer.2021

    • Author(s)
      Imai, H., T. Kishikawa, H. Minemura, Y. Yamada, T. Ibe, O. Yamaguchi, A. Mouri, Y. Hamamoto, K. Kanazawa, T. Kasai, K. Kaira, T. Kaburagi, K. Minato, K. Kobayashi, and H. Kagamu.
    • Journal Title

      Cancer Med.

      Volume: 10 Issue: 20 Pages: 6971-6984

    • DOI

      10.1002/cam4.4220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Antitumor Immunity Evaluated via the Peripheral Blood2021

    • Author(s)
      Kagamu, H.
    • Journal Title

      Gan To Kagaku Ryoho.

      Volume: 48 Pages: 315-319

    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Post-Progression Survival Influences Overall Survival among Patients with Advanced Non-Small Cell Lung Cancer Undergoing First-Line Pembrolizumab Monotherapy.2021

    • Author(s)
      Imai, H., T. Kishikawa, H. Minemura, Y. Yamada, T. Ibe, K. Mori, O. Yamaguchi, A. Mouri, Y. Hamamoto, K. Kanazawa, T. Kasai, K. Kaira, T. Kaburagi, K. Minato, K. Kobayashi, and H. Kagamu.
    • Journal Title

      Oncology.

      Volume: 99 Issue: 9 Pages: 562-570

    • DOI

      10.1159/000516745

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] CD4(+) T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy.2020

    • Author(s)
      Kagamu H, Kitano S, Yamaguchi O, Yoshimura K, Horimoto K, Kitazawa M, et al.
    • Journal Title

      Cancer Immunol Res

      Volume: 8 Issue: 3 Pages: 334-344

    • DOI

      10.1158/2326-6066.cir-19-0574

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04184, KAKENHI-PROJECT-17K09665
  • [Journal Article] Systemic CD4 immunity: A powerful clinical biomarker for PD-L1/PD-1 immunotherapy.2020

    • Author(s)
      Zuazo, M., Arasanz, H., Bocanegra, A., Chocarro, L., Vera, R., Escors, D., Kagamu, H., and Kochan, G.
    • Journal Title

      EMBO Mol Med

      Volume: 12 Issue: 1 Pages: 212706-212706

    • DOI

      10.1007/s00280-019-03984-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Efficacy of PD-1 blockade therapy and T cell immunity in lung cancer patients.2020

    • Author(s)
      Kagamu, H., and Kaira, K.
    • Journal Title

      Immunol Med

      Volume: 43 Issue: 1 Pages: 10-15

    • DOI

      10.1080/25785826.2019.1710427

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Efficacy and safety of first-line pembrolizumab monotherapy in elderly patients (aged > 75 years) with non-small cell lung cancer.2020

    • Author(s)
      Imai H, Wasamoto S, Yamaguchi O, Suzuki K, Sugiyama T, Uchino J, Minemura H, Osaki T, Ishii H, Umeda Y, Mori K, Kotake M, Kagamu H, Morozumi N, Taniguchi H, Kasai T, Minato K, Kaira K.
    • Journal Title

      Journal of Cancer Research and Clinical Oncology

      Volume: 146 Issue: 2 Pages: 457-466

    • DOI

      10.1007/s00432-019-03072-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08119, KAKENHI-PROJECT-17H04184
  • [Journal Article] Chemoradiotherapy followed by durvalumab in patients with unresectable advanced non‐small cell lung cancer: Management of adverse events2020

    • Author(s)
      Miura Yu、Mouri Atsuto、Kaira Kyoichi、Yamaguchi Ou、Shiono Ayako、Hashimoto Kosuke、Nishihara Fuyumi、Shinomiya Shun、Akagami Tomoe、Murayama Yoshitake、Abe Takanori、Noda Shin‐ei、Kato Shingo、Kobayashi Kunihiko、Kagamu Hiroshi
    • Journal Title

      Thoracic Cancer

      Volume: 11 Issue: 5 Pages: 1280-1287

    • DOI

      10.1111/1759-7714.13394

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09665, KAKENHI-PROJECT-17H04184
  • [Journal Article] Psuedoprogression mimicking hyperprogressive disease after pembrolizumab treatment in a patient with lung cancer.2020

    • Author(s)
      Hashimoto K, Kaira K, Kawasaki T, Yamaguchi O, Kagamu H.
    • Journal Title

      Lung Cancer

      Volume: 139 Pages: 221-223

    • DOI

      10.1016/j.lungcan.2019.11.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184, KAKENHI-PROJECT-16K08654
  • [Journal Article] D4(+) T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy.2020

    • Author(s)
      Kagamu, H., Kitano, S., Yamaguchi, O., Yoshimura, K., Horimoto, K., Kitazawa, M., Fukui, K., Shiono, A., Mouri, A., Nishihara, F., Miura, Y., Hashimoto, K., Murayama, Y., Kaira, K., and Kobayashi, K.
    • Journal Title

      Cancer Immunol Res

      Volume: 8 Pages: 334-344

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Drastic Response of Re-challenge of EGFR-TKIs Immediately After Nivolumab Therapy in EGFR-TKI-Resistant Patients.2019

    • Author(s)
      Kaira K, Kagamu H.
    • Journal Title

      J Thorac Oncol

      Volume: 14 Issue: 6 Pages: e135-e136

    • DOI

      10.1016/j.jtho.2019.02.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Different incidence of interstitial lung disease according to different kinds of EGFR‐tyrosine kinase inhibitors administered immediately before and/or after anti‐PD‐1 antibodies in lung cancer2019

    • Author(s)
      Uchida Takahiro、Kaira Kyoichi、Yamaguchi Ou、Mouri Atsuto、Shiono Ayako、Miura Yu、Hashimoto Kosuke、Nishihara Fuyumi、Murayama Yoshitake、Kobayashi Kunihiko、Kagamu Hiroshi
    • Journal Title

      Thoracic Cancer

      Volume: 10 Issue: 4 Pages: 975-979

    • DOI

      10.1111/1759-7714.13039

    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Journal Article] Combination Therapy with Carboplatin and Paclitaxel for Small Cell Lung Cancer2019

    • Author(s)
      Atsuto Mouri, Ou Yamaguchi, Sachiko Miyauchi, Ayako Shiono, Harue Utsugi, Fuyumi Nishihara, Yoshitake Murayama, Hiroshi Kagamu, Kunihiko Kobayashi
    • Journal Title

      Respiratory investigation

      Volume: 57 Issue: 1 Pages: 34-39

    • DOI

      10.1016/j.resinv.2018.09.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16058, KAKENHI-PROJECT-17K09665
  • [Journal Article] Radiotherapy is an independent prognostic marker of favorable prognosis in non‐small cell lung cancer patients after treatment with the immune checkpoint inhibitor, nivolumab2019

    • Author(s)
      Yamaguchi Ou、Kaira Kyoichi、Hashimoto Kosuke、Mouri Atsuto、Miura Yu、Shiono Ayako、Nishihara Fuyumi、Murayama Yoshitake、Noda Shin‐ei、Kato Shingo、Kobayashi Kunihiko、Kagamu Hiroshi
    • Journal Title

      Thoracic Cancer

      Volume: 10 Issue: 4 Pages: 992-1000

    • DOI

      10.1111/1759-7714.13044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04184, KAKENHI-PROJECT-17K16058, KAKENHI-PROJECT-17K09665
  • [Journal Article] Improved efficacy of ramucirumab plus docetaxel after nivolumab failure in previously treated non‐small cell lung cancer patients2019

    • Author(s)
      Shiono Ayako、Kaira Kyoichi、Mouri Atsuto、Yamaguchi Ou、Hashimoto Kosuke、Uchida Takahiro、Miura Yu、Nishihara Fuyumi、Murayama Yoshitake、Kobayashi Kunihiko、Kagamu Hiroshi
    • Journal Title

      Thoracic Cancer

      Volume: 10 Issue: 4 Pages: 775-781

    • DOI

      10.1111/1759-7714.12998

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04184, KAKENHI-PROJECT-17K16058, KAKENHI-PROJECT-17K09665
  • [Journal Article] Clinical difference between discontinuation and retreatment with nivolumab after immune-related adverse events in patients with lung cancer2019

    • Author(s)
      Mouri Atsuto、Kaira Kyoichi、Yamaguchi Ou、Shiono Ayako、Miura Yu、Hashimoto Kosuke、Nishihara Fuyumi、Murayama Yoshitake、Kobayashi Kunihiko、Kagamu Hiroshi
    • Journal Title

      Cancer Chemotherapy and Pharmacology

      Volume: 84 Issue: 4 Pages: 873-880

    • DOI

      10.1007/s00280-019-03926-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09665
  • [Journal Article] Induction of immune reaction in benign melanocytic neviwithout halo during nivolumab therapy in a patient with melanoma2017

    • Author(s)
      Yasuhiro Nakamura, Takashi Fujino, Hiroshi Kagamu, Taisuke Matsuya, Yukiko Teramoto, Yuri Aasami, Akifumi Yamamoto
    • Journal Title

      JAMA Dermatology

      Volume: 153 Issue: 8 Pages: 832

    • DOI

      10.1001/jamadermatol.2017.0615

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Journal Article] Megalin Blockade with Cilastatin Suppresses Drug-Induced Nephrotoxicity.2017

    • Author(s)
      Hori Y, Aoki N, Kuwahara S, Hosojima M, Kaseda R, Goto S, Iida T, De S, Kabasawa H, Kaneko R, Aoki H, Tanabe Y, Kagamu H, Narita I, Kikuchi T, Saito A.
    • Journal Title

      J Am Soc Nephrol.

      Volume: January 4 Issue: 2 Pages: 227-234

    • DOI

      10.1007/s10637-017-0436-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293196, KAKENHI-PROJECT-26461182
  • [Journal Article] Anamorelin (ONO-7643) in Japanese patients with non-small cell lung cancer and cachexia: results of a randomized phase 2 trial.2016

    • Author(s)
      Takayama, K., Katakami, N., Yokoyama, T., Atagi, S., Yoshimori, K., Kagamu, H., Saito, H., Takiguchi, Y., Aoe, K., Koyama, A., Komura, N. and Eguchi, K
    • Journal Title

      Supportive care in cancer

      Volume: NA Issue: 8 Pages: 1-11

    • DOI

      10.1007/s00520-016-3144-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461182, KAKENHI-PROJECT-26293196
  • [Journal Article] Nephrotoxicity of cisplatin combination chemotherapy in thoracic malignancy patients with CKD risk factors.2016

    • Author(s)
      Ko Sato, Satoshi Watanabe,corresponding author Aya Ohtsubo, Satoshi Shoji, Daisuke Ishikawa, Tomohiro Tanaka, Koichiro Nozaki, Rie Kondo, Masaaki Okajima, Satoru Miura, Junta Tanaka, Takuro Sakagami, Toshiyuki Koya, Hiroshi Kagamu, Hirohisa Yoshizawa, and Ichiei Narita
    • Journal Title

      BMC Cancer

      Volume: 16(1) Issue: 1 Pages: 222-222

    • DOI

      10.1186/s12885-016-2271-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860637, KAKENHI-PROJECT-26293196, KAKENHI-PROJECT-15K09168
  • [Journal Article] A phase II study of bevacizumab with carboplatin-pemetrexed in non-squamous non-small cell lung carcinoma patients with malignant pleural effusions: North East Japan Study Group Trial NEJ013A.2016

    • Author(s)
      Usui K, Sugawara S, Nishitsuji M, Fujita Y, Inoue A, Mouri A, Watanabe H, Sakai H, Kinoshita I, Ohhara Y, Maemondo M, Kagamu H, Hagiwara K, Kobayashi K
    • Journal Title

      Lung Cancer

      Volume: 99 Pages: 131-136

    • DOI

      10.1016/j.lungcan.2016.07.003

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293196, KAKENHI-PROJECT-26461175
  • [Journal Article] Critical Roles of Chemoresistant Effector and Regulatory T Cells in Antitumor Immunity after Lymphodepleting Chemotherapy.2015

    • Author(s)
      Saida Y, Watanabe S, Tanaka T, Baba J, Sato K, Shoji S, Igarashi N, Kondo R, Okajima M, Koshio J, Ichikawa K, Nozaki K, Ishikawa D, Koya T, Miura S, Tanaka J, Kagamu H, Yoshizawa H, Nakata K, Narita I
    • Journal Title

      Journal of immunology

      Volume: 195 Pages: 726-735

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09168
  • [Journal Article] Critical Roles of Chemoresistant Effector and Regulatory T Cells in Antitumor Immunity after Lymphodepleting Chemotherapy.2015

    • Author(s)
      Saida Y, Watanabe S, Tanaka T, Baba J, Sato K, Shoji S, Igarashi N, Kondo R, Okajima M, Koshio J, Ichikawa K, Nozaki K, Ishikawa D, Koya T, Miura S, Tanaka J, Kagamu H, Yoshizawa H, Nakata K, Narita I
    • Journal Title

      Journal of immunology

      Volume: 195(2) Issue: 2 Pages: 726-735

    • DOI

      10.4049/jimmunol.1401468

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860637, KAKENHI-PROJECT-26293196
  • [Journal Article] DDX3X induces primary EGFR-TKI resistance based on intratumor heterogeneity in lung cancer cells harboring EGFR-activating mutations.2014

    • Author(s)
      Nozaki K, Yoshizawa H et al.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 10 Pages: e111019-e111019

    • DOI

      10.1371/journal.pone.0111019

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-26293196
  • [Journal Article] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is an immunogenic target of cancer stem cells2013

    • Author(s)
      Koshio, J. Kagamu, H. Nozaki, K. Saida, Y. Tanaka, T. Shoji, S. Igarashi, N. Miura, S. Okajima, M. Watanabe, S. Yoshizawa, H. Narita, I.
    • Journal Title

      Cancer Immunol Immunother

      Volume: 62 Issue: 10 Pages: 1619-28

    • DOI

      10.1007/s00262-013-1467-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591141, KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-25860637
  • [Journal Article] mTOR inhibitors control erlotinib-resistance of EGFR mutant lung cancer cells triggered by HGF.2013

    • Author(s)
      Ishikawa D, Yano S, et al.
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 5 Pages: e62104-e62104

    • DOI

      10.1371/journal.pone.0062104

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23591141, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-25860638, KAKENHI-PROJECT-25860640
  • [Journal Article] IL-17 eliminates therapeutic effects of oral tolerance in murine airway allergic inflammation.2012

    • Author(s)
      Kawakami, H., Koya, T., Kagamu, H., Kimura, Y., Sakamoto, H., Yamabayashi, C., Furukawa, T., Sakagami, T., Miyabayashi, T., Hasegawa, T., Suzuki, E. and Narita, I.
    • Journal Title

      Clin Exp Allergy

      Volume: 42 Issue: 6 Pages: 946-957

    • DOI

      10.1111/j.1365-2222.2012.04006.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Journal Article] Depletion of radio-resistant regulatory T cells enhances antitumor immunity during recovery from lymphopenia.2012

    • Author(s)
      Baba, J., Watanabe, S., Saida, Y., Tanaka, T., Miyabayashi, T., Koshio, J., Ichikawa, K., Nozaki, K., Miura, S., Tanaka, H., Tanaka, J., Kagamu, H., Yoshizawa, H., Nakata, K. and Narita, I.
    • Journal Title

      Blood

      Volume: 120 Issue: 12 Pages: 2417-27

    • DOI

      10.1182/blood-2012-02-411124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Journal Article] Depletion of radio-resistant regulatory T cells enhances antitumor immunity during recovery from lymphopenia.2012

    • Author(s)
      Baba J, Watanabe S, Saida Y, Tanaka T, Miyabayashi T, Koshio J, Ichikawa K, Nozaki K, Koya T, Deguchi K, Tan C, Miura S, Tanaka H, Tanaka J, Kagamu H, Yoshizawa H, Nakata K, Narita I.
    • Journal Title

      Blood

      Volume: 120 Pages: 2417-2427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591157
  • [Journal Article] Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity.2012

    • Author(s)
      Ichikawa, K., Kagamu, H., Koyama, K., Miyabayashi, T., Koshio, J., Miura, S., Watanabe, S., Yoshizawa, H. and Narita, I.
    • Journal Title

      Vaccine

      Volume: 30 Issue: 43 Pages: 6190-7

    • DOI

      10.1016/j.vaccine.2012.07.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591141, KAKENHI-PROJECT-24591156
  • [Journal Article] Epitope diversification driven by non-tumor epitope-specific Th1 and Th17 mediates potent antitumor reactivity.2012

    • Author(s)
      Ichikawa K, Kagamu H, Koyama K, Miyabayashi T, Koshio J, Miura S, Watanabe S, Yoshizawa H, Narita I.
    • Journal Title

      Vaccine

      Volume: 30 Pages: 6190-6197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591157
  • [Journal Article] Vaccination with CD133(+) melanoma induces specific Th17 and Th1 cell-mediated antitumor reactivity against parental tumor2011

    • Author(s)
      宮林貴大、各務博、渡部聡、吉澤弘久、成田一衛
    • Journal Title

      Cancer Immunol Immunother

      Pages: 1597-608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] Vaccination with CD133(+) melanoma induces specific Th17 and Th1 cell-mediated antitumor reactivity against parental tumor2011

    • Author(s)
      Miyabayashi T, Yoshizawa H, et al
    • Journal Title

      Cancer Immunol Immunother

      Volume: 11 Issue: 11 Pages: 1597-608

    • DOI

      10.1007/s00262-011-1063-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590983, KAKENHI-PROJECT-21590984, KAKENHI-PROJECT-23591141
  • [Journal Article] Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy : a retrospective analysis2011

    • Author(s)
      渡部聡、田中純太、太田毅、近藤利恵、田中洋史、各務博、市川紘将、古塩純、馬場順子、宮林貴大、成田一衛、吉澤弘久
    • Journal Title

      BMC Cancer

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] Clinical responses to EGFR-tyrosine kinase inhibitor retreatmentin non-small cell lung cancer patients who benefited from prioreffective gefitinib therapy a retrospective analysis.2011

    • Author(s)
      渡部聡、田中純太、太田毅、近藤利恵、田中洋史、各務博、市川紘将、古塩純、馬場 順子、宮林貴大、成田一衛、吉澤弘久
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] Henoch Schonlein purpura associated with pulmonary adenocarcinoma2011

    • Author(s)
      三船大樹、渡部聡、近藤利恵、和田庸子、森山寛史、各務博、吉沢弘久、手塚貴文、松山麻子、成田一衛
    • Journal Title

      Journal of medical case report

      Volume: 5 Pages: 226-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis2011

    • Author(s)
      Watanabe, S. Tanaka, J. Ota, T. Kondo, R. Tanaka, H. Kagamu, H. Ichikawa, K. Koshio, J. Baba, J. Miyabayashi, T. Narita, I. Yoshizawa, H.
    • Journal Title

      BMC Cancer

      Volume: 11 Issue: 1 Pages: 1-1

    • DOI

      10.1186/1471-2407-11-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Journal Article] A Prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice.2010

    • Author(s)
      Hayashi M, Koya T, Kagamu H, et al.
    • Journal Title

      Clin Exp Allergy 40

      Pages: 317-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] 喫煙再開により再燃を認めた急性好酸球性肺炎の1例2010

    • Author(s)
      三船大樹、渡部聡、近藤利恵、森山寛史、各務博、高田俊範、成田一衛、長谷川隆志、鈴木栄一、手塚貴文
    • Journal Title

      新潟医学会雑誌

      Pages: 407-412

    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] A prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice.2010

    • Author(s)
      Hayashi, M., T.Koya, H.Kawakami, T.Sakagami, T.Hasegawa, H.Kagamu, T.Takada, Y.Sakai, E.Suzuki, E.W.Gelfand, F.Gejyo.
    • Journal Title

      Clin Exp Allergy 40

      Pages: 317-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] A prostacyclin agonist with thromboxane inhibitory activity for airway allergic inflammation in mice.2010

    • Author(s)
      Hayashi M, Koya T, Kagamu H, et al.
    • Journal Title

      Clin Exp Allergy

      Pages: 371-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Anti-interferon-gamma autoantibody in a patient with disseminated Mycobacterium avium complex.2009

    • Author(s)
      Koya, T., C.Tsubata, H.Kagamu, K.Koyama, M.Hayashi, K.Kuwabara, T.Itoh, Y.Tanabe, T.Takada, F.Gejyo.
    • Journal Title

      J Infect Chemother 15

      Pages: 118-122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Effect of ciclesonide on bronchial asthma in athletes.2009

    • Author(s)
      Koya, T., T.Hasegawa, J.Tanaka, H.Kawakami, M.Hayashi, H.Kagamu, I.Narita, M.Arakawa, E.Suzuki.
    • Journal Title

      J Asthma 46

      Pages: 1032-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer.2009

    • Author(s)
      Hayashi, Y., H.Kuriyama, H.Umezu, J.Tanaka, T.Yoshimasu, T.Furukawa, H.Tanaka, H.Kagamu, F.Gejyo, H.Yoshizawa.
    • Journal Title

      Intern Med 48

      Pages: 203-208

    • NAID

      130000122350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Effect of ciclesonide on bronchial asthma in athletes.2009

    • Author(s)
      Koya T, Kagamu H, et al.
    • Journal Title

      J Asthma 46

      Pages: 1032-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer.2009

    • Author(s)
      Yoshiki Hayashi, Hideyuki Kuriyama, Hiroshi Umezu, Junta Tanaka, T. Yoshimasu, T. Furukawa, Hiroshi Tanaka, Hiroshi Kagamu, Fumitake Gejyo, Hirohisa Yoshizawa.
    • Journal Title

      Internal medicine 48

      Pages: 203-208

    • NAID

      130000122350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Anti-interferon-gamma autoantibody in a patient with disseminated Mycobacterium avium complex.2009

    • Author(s)
      Koya T, Kagamu H, et al.
    • Journal Title

      J Infect Chemother 15

      Pages: 118-122

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Class III beta-tubulin expression in tumor cells is correlated with resistance to docetaxel in patients with completely resected non-small-cell lung cancer2009

    • Author(s)
      各務博、吉澤弘久(他8名10番目)
    • Pages
      203-8
    • NAID

      130000122350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Journal Article] Timing of CD40 Ligation for RNA-Pulsed DCs to Induce Antitumor Immunity.2008

    • Author(s)
      Satoru Miura, Hiroshi KagamuHiroshi Tanaka, Hirohisa Yoshizawa, Fumitake Gejyo
    • Journal Title

      Scandinavian journal of immunology. 67

      Pages: 385-391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Appropriate timing of CD40 ligation for RNA-pulsed DCs to induce antitumor immunity2008

    • Author(s)
      Satoshi, Miura, Hiroshi, Kagamu, Hiroshi, Tanaka, Hirohisa, Yoshizawa, Fumitake, Gejyo
    • Journal Title

      Scandinavian Journal of Immunology 67

      Pages: 385-391

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Reciprocal CD4^+ T-cell balance of effector CD62L^<low> CD4^+ and CD62L^<high>CD25^+ CD4^+ regulatory T cells in small cell lung cancer reflects disease stage.2008

    • Author(s)
      Koyama, K., H.Kagamu, S.Miura, T.Hiura, T.Miyabayashi, R.Itoh, H. Kuriyama, H.Tanaka, J.Tanaka, H.Yoshizawa, K. Nakata, F.Gejyo
    • Journal Title

      Clin Cancer Res 14

      Pages: 6770-6779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Appropriate timing of CD40 ligation for RNA-pulsed DCs to induce antitumor immunity2008

    • Author(s)
      Satoshi Miura, Hiroshi Kagamu, Hiroshi Tanaka, Hirohisa Yoshizawa, Fumitake Gejyo
    • Journal Title

      Scandinavian Journal of Immunology 67

      Pages: 385-391

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Reciprocal CD4^+ T-Cell Balance of Effector CD62L^<low> CD4^+ and CD62L^<high>CD25^+ CD4^+ Regulatory T Cells in Small Cell Lung Cancer Reflects Disease Stage.2008

    • Author(s)
      Kenichi Koyama, Hiroshi Kagamu, Satoru Miura, Toru Hiura, Takao Miyabayashi, Ryo Itoh, Hideyuki Kuriyama, Hiroshi Tanaka, Junta Tanaka, Hirohisa Yoshizawa, Koh Nakata, Fumitake Gejyo
    • Journal Title

      Clin Cancer Res 14

      Pages: 6770-6779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Appropriate timing of CD40 ligation for RNA-Pulsed DCs to induce antitumor immunity.2008

    • Author(s)
      Miura, S., H.Kagamu, H.Tanaka, H.Yoshizawa, F.Gejyo.
    • Journal Title

      Scand J Immunol 67

      Pages: 385-391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Journal Article] Generation of anti-tumor effector T cells from naive T cells by stimulation with dendritic/tumor fusion cells.2007

    • Author(s)
      Akira Ishida, Hiroshi Tanaka, Toru Hiura, Satoshi Miura, Satoshi Watanabe, Koki Matsuyama, Hideyuki Kuriyama, Junta Tanaka, Hiroshi Kagamu, Fumitake Gejyo, Hirohisa Yoshizawa
    • Journal Title

      Scandinavian Journal of Immunology 66

      Pages: 546-554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals2007

    • Author(s)
      Masato, Watanabe., Kanji, Uchida., Kazuhide. Nakagaki., Hiroko. Kanazawa., Bruce C, Trapnell., Yoshihiko. Hoshino, Hiroshi. Kagamu, Hirohisa. Yoshizawa, Naoto. Keicho, Hajime. Goto, Koh. Nakata
    • Journal Title

      FEBS letters 581

      Pages: 2017-2021

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals2007

    • Author(s)
      Masato Watanabe, Kanji Uchida, Kazuhide Nakagaki, Hiroko Kanazawa, Bruce C. Trapnell, Yoshihiko Hoshino, Hiroshi Kagamu, Hirohisa Yoshizawa, Naoto Keicho, Hajime Goto, Koh Nakata
    • Journal Title

      FEBS letters 581

      Pages: 2017-2021

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Generation of anti-tumor effector T cells from naive T cells by stimulation with dendritic/tumor fusion cells2007

    • Author(s)
      Akira, Ishida, Hiroshi, Tanaka, Toru, Hiura, Satoshi, Miura, Satoshi, Watanabe, Koki, Matsuyama, Hideyuki, Kuriyama, Junta, Tanaka, Hiroshi, Kagamu, Fumitake, Geiyo, Hirohisa, Yoshizawa
    • Journal Title

      Scandinavian Journal of Immunology 66

      Pages: 546-554

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Generation of anti-tumor effctor T cells from naive T cells by stimulation with dendritic/tumor fusion cells.2007

    • Author(s)
      Akira Ishida, Hiroshi Tanaka, Toru Hiura, Satoshi Miura, Satoshi Watanabe, Koki Matsuyama, Hideyuki Kuriyama, Junta Tanaka, Hiroshi Kagamu, Fumitake Gejyo, Hirohisa Yoshizawa
    • Journal Title

      Scandinavian Journal of Immunology 66

      Pages: 546-554

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Journal Article] Anti-cytokine autoantibodies are ubiquitous in healthy individuals.2007

    • Author(s)
      Watanabe M, Uchida K, Nakagaki K, Kanazawa H, Trapnell B. C., Hoshino Y, Kagamu H, Yoshizawa H, Keicho N, Goto H, and Nakata K.
    • Journal Title

      FEBS Letters 581(10)

      Pages: 2017-2021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659291
  • [Journal Article] Both Regulatory T Cells and Antitumor Effector T Cells Are Primed in the Same Draining Lymph Nodes during Tumor Progression.2005

    • Author(s)
      Hiura, T., Kagamu, H., Miura, S., Ishida, A., Tanaka, H., Tanaka, J., Gejyo, F., Yoshizawa, H.
    • Journal Title

      Journal of Immunology 175

      Pages: 5058-5066

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590741
  • [Patent] 癌治療に対する応答を予測するためのバイオマーカー2021

    • Inventor(s)
      各務 博
    • Industrial Property Rights Holder
      各務 博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Acquisition Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] 末梢血Thクラスターによるがん免疫療法効果の予測2020

    • Inventor(s)
      各務 博
    • Industrial Property Rights Holder
      各務 博
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-150620
    • Filing Date
      2020
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] 放射線治療による抗腫瘍免疫効果を評価する末梢血バイオマーカー2019

    • Inventor(s)
      各務博
    • Industrial Property Rights Holder
      各務博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] 放射線治療による抗腫瘍免疫効果を評価する末梢血バイオマーカー2019

    • Inventor(s)
      各務博
    • Industrial Property Rights Holder
      各務博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] がん免疫療法における長期生存を予測するための方法および組成物2019

    • Inventor(s)
      各務博
    • Industrial Property Rights Holder
      各務博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] がん免疫療法における長期生存を予測するための方法および組成物2019

    • Inventor(s)
      各務博
    • Industrial Property Rights Holder
      各務博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] PD-1免疫チェックポイント阻害薬の臨床効果を予測する免疫学的バイオマーカー2018

    • Inventor(s)
      各務博
    • Industrial Property Rights Holder
      各務博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Patent] 免疫チェックポイント阻害薬の臨床効果を予測する免疫学的バイオマーカー2017

    • Inventor(s)
      各務 博
    • Industrial Property Rights Holder
      各務 博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017-02-07
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Patent] 癌幹細胞に発現する分子をターゲットとした癌を診断、治療する方法2013

    • Inventor(s)
      各務博、成田一衛、林隆史、後藤義博
    • Industrial Property Rights Holder
      各務博、成田一衛、林隆史、後藤義博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-09-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Patent] 癌幹細胞に発現する分子をターゲットとした癌を診断、治療する方法2012

    • Inventor(s)
      各務博、成田一衛、林隆史、後藤義博
    • Industrial Property Rights Holder
      各務博、成田一衛、林隆史、後藤義博
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-09-04
    • Acquisition Date
      2013-09-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] scRNAseqが明らかにするがん免疫サイクルCD4+ T細胞クラスター2023

    • Author(s)
      各務博、山崎智、柳原章寿、二反田博之、橋本康佑、今井久雄、解良恭2、田口亮、梅崎徹也、坂口浩三、石田博徳、小林国彦、堀本勝久
    • Organizer
      日本呼吸器学会
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] 新規Th1-like CD4+ T細胞クラスターが予測する抗腫瘍免疫2023

    • Author(s)
      各務 博
    • Organizer
      日本バイオセラピィ学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] がん治癒をもたらす抗腫瘍免疫メカニズム2023

    • Author(s)
      各務 博
    • Organizer
      日本呼吸器外科学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] 抗腫瘍免疫を司る2つのTh1-like CD4+ T-cell clusters2023

    • Author(s)
      各務 博
    • Organizer
      日本肺癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] scRNAseqが明らかにする がん免疫サイクルCD4+ T細胞クラスター2023

    • Author(s)
      各務博、山崎智、柳原章寿、二反田博之、橋本康佑、今井久雄、解良恭一、田口亮、梅崎徹也、坂口浩三、石田博徳、小林国彦、堀本勝久
    • Organizer
      日本呼吸器学会
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] 進化する免疫療法への挑戦 ~非小細胞肺癌における治療効果予測~2023

    • Author(s)
      各務 博
    • Organizer
      日本癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] 周術期の末梢血CD4+T細胞免疫評価による非小細胞肺癌術後の無病生存期間の予測2022

    • Author(s)
      栁原章寿, 山﨑智, 橋本康佑, 田口亮, 梅咲徹也, 今井久雄, 解良恭一, 二反田博之, 坂口浩三, 石田博徳, 小林国彦, 堀本勝久, 各務博
    • Organizer
      日本肺癌学会
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] Discovery of a new CD4+ T cell cluster that correlates PD-1 blockade efficacy2022

    • Author(s)
      Hiroshi Kagamu, Satoshi Yamasak, Shigehisa Kitano, Ou Yamaguchi, Atsuhito Mouri, Ayako Shiono, Fuyumi Nishihara, Yu Miura, Kosuke Hashimoto, Hisao Imai, Kyoichi Kaira, Kunihiko Kobayashi, Yae Kanai, Tatsuhiro Shibata, and Katsuhisa Horimoto
    • Organizer
      European Society of Medical Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] Correlation with T-cell immunity and EGFR-TKI treatment in patient harboring EGFR driver mutation2022

    • Author(s)
      Atsuto Mouri, Kyouichi Kaira, Ou Yamaguchi, Ayako Shiono, Yu Miura, Kousuke Hashimoto, Fuyumi Nishihara, Hisao Imai, Kunihiko Kobayashi, Hiroshi Kagamu
    • Organizer
      European Society of Medical Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24341
  • [Presentation] 抗腫瘍免疫のメカニズムと末梢血バイオマーカー2021

    • Author(s)
      各務 博
    • Organizer
      がん分子標的治療学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 新時代を迎える免疫チェックポイント阻害薬治療2021

    • Author(s)
      各務 博
    • Organizer
      日本呼吸器学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 複合がん免疫療法の現状と課題2021

    • Author(s)
      各務 博
    • Organizer
      日本がん免疫療法学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 抗腫瘍免疫の理解からIO-IO時代の 進行期肺癌薬物療法を考える2021

    • Author(s)
      各務 博
    • Organizer
      日本肺癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] Unsupervised clusteringで明らかになる 抗腫瘍免疫T細胞クラスター2021

    • Author(s)
      各務 博
    • Organizer
      日本血液疾患免疫療法学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] single cellベース分子発現解析が拓く 免疫の理解2021

    • Author(s)
      各務 博
    • Organizer
      日本アレルギー学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 腫瘍免疫の理解&#12316;single cell RNAseqで何がわかるか2020

    • Author(s)
      各務 博
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 新時代を迎える進行期肺癌薬物療法2020

    • Author(s)
      各務 博
    • Organizer
      日本肺癌学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] がん免疫療法におけるバイオマーカーと複合免疫療法2020

    • Author(s)
      各務 博
    • Organizer
      日本泌尿器科学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 免疫チェックポイント阻害薬のバイオマーカー2020

    • Author(s)
      各務 博
    • Organizer
      日本肺癌学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 解明される腫瘍免疫のメカニズム2020

    • Author(s)
      各務 博
    • Organizer
      がん分子標的治療学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 小細胞肺癌治療が抗腫瘍免疫に及ぼす影響2019

    • Author(s)
      西原冬実、四宮俊、橋本康佑、三浦雄、塩野文子、山口央、毛利篤人、村山芳武、解良恭一、小林国彦、各務博
    • Organizer
      第17回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K09665
  • [Presentation] 肺癌の免疫療法2019

    • Author(s)
      各務博
    • Organizer
      日本呼吸器学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 免疫チェックポイント阻害薬の奏効メカニズムとバイオマーカー2019

    • Author(s)
      各務博
    • Organizer
      日本免疫治療学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] CD4+ T-cell immunity predicted long-surviving NSCLC patients after PD-1 blockade therapy2019

    • Author(s)
      Kyoichi Kaira, Ou Yamaguchi, Atsuto Mouri, Ayako Shiono, Fuyumi Nishihara, Yu Miura, Shun Shinomiya, Kosuke Hashimoto, Yoshitake Murayama, Shigehiko Kitano, Kunihiko Kobayashi, and Hiroshi Kagamu
    • Organizer
      ASCO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] Phase II study to evaluate the peripheral blood mononuclear cell biomarker for nivolumab efficacy on previously treated non-small cell lung cancer subjects2019

    • Author(s)
      Yosuke Kawashima, Ou Yamaguchi, Kozuki Toshiyuki, Naoki Furuya, Futoshi Kurimoto, Takae Okuno, Tadaaki Yamada, Kenichiro Komiyama, Ko Ryo, Yoshiaki Nagai, Nobuhisa Ishikawa, Toshiyuki Harada, Kana Watanabe, Seike Masahiro, Kenichi Yoshimura, Kunihiko Kobayashi, Hiroshi Kagamu
    • Organizer
      ESMO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] Immunological impact of surgery in NSCLC patients2019

    • Author(s)
      Akitoshi Yanagihara, Hiroshi Kagamu, 1Hirozo Sakaguchi, Hironori Ishida, et al.
    • Organizer
      ESMO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 免疫チェックポイント阻害薬治療における免疫機能評価2019

    • Author(s)
      各務博
    • Organizer
      日本呼吸器学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] Effector CD4+ T-cell induction by thoracic radiotherapy for NSCLC patients2019

    • Author(s)
      Yu Miura, Koko Kodaira, Megumi Kenmochi, Tomoko Yamashiro, Ou Yamaguchi, Ayako Shiono, Atsuhito Mouri, Fuyumi Nishihara, Shun Shinomiya, Kosuke Hashimoto, Yoshitake Murayama, Kunihiko Kobayashi, Kyoichi Kaira, and Hiroshi Kagamu
    • Organizer
      ESMO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 小細胞肺癌標準治療が及ぼす免疫学的影響2018

    • Author(s)
      西原冬実、山口央、毛利篤人、塩野文子、内田貴裕、橋本康佑、三浦雄、村山芳武、解良恭一、小林国彦、各務博
    • Organizer
      日本臨床腫瘍学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 肺癌に対するPD-1阻害薬効果とT細胞免疫2018

    • Author(s)
      各務博
    • Organizer
      日本臨床免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] irAEとは何か2018

    • Author(s)
      各務博
    • Organizer
      日本医療薬学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] ニボルマブによるirILDと予後、効果、末梢血CD62Llow CD4+ T細胞との関係2018

    • Author(s)
      山口央、毛利篤人、塩野文子、内田貴裕、橋本康佑、西原冬実、三浦雄、村山芳武、解良恭一、小林国彦、各務博
    • Organizer
      日本肺癌学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] メカニズムから考える免疫チェックポイント阻害薬の未来2018

    • Author(s)
      各務博
    • Organizer
      呼吸器外科学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 肺がん領域におけるPD-1阻害薬の知見と課題2018

    • Author(s)
      各務博
    • Organizer
      日本がん免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 末梢血T細胞解析によるPD-1阻害薬効果予測2018

    • Author(s)
      各務博
    • Organizer
      日本肺癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] CD4+ T cells in PBMC predict the outcome of anti-PD-1 therapy2017

    • Author(s)
      Hiroshi Kagamu et al.
    • Organizer
      American Society of Clinical Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] CD4+ T cells in PBMC tell us who will respond to anti-PD-1 Ab therapy2017

    • Author(s)
      各務博 et al.
    • Organizer
      日本がん学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] 治療前末梢血CD4+ T細胞免疫評価を用いた抗PD-1抗体治療効果予測2017

    • Author(s)
      山口央、各務博 et al.
    • Organizer
      日本肺癌学会
    • Data Source
      KAKENHI-PROJECT-17H04184
  • [Presentation] DDX3X dependent VEGFR expression in lung cancer cells harboring EGFR mutation resulted in EGFR-TKI resistance2016

    • Author(s)
      Aya Otsubo, Hiroshi Kagamu, Satoshi Shoji, Toshiaki Kikuchi
    • Organizer
      癌学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] Programmed death receptor-1/programmed death receptor ligand-1 blockade improves priming of antitumor effector T cells after cytotoxic therapies2016

    • Author(s)
      Miho Takahashi, Satoshi Watanabe, Ko Sato, Tomohiro Tanaka, Yu Saida, Junko Baba, Aya Ohtsubo, Miyuki Sato, Rie Kondo, Masaaki Okajima, Junta Tanaka, Hiroshi Kagamu, Hirohisa Yoshizawa, Toshiaki Kikuchi
    • Organizer
      Annual meeting of american association for cancer research
    • Place of Presentation
      New Orleans (アメリカ合衆国)
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09168
  • [Presentation] 抗腫瘍効果を担う免疫状態を反映するバイオマーカー2016

    • Author(s)
      各務 博,渡部 聡,山口 央,塩野 文子,宮内 幸子,前野 有理,宇津木 春枝,小林 国彦
    • Organizer
      癌病態治療研究会
    • Place of Presentation
      三井ガーデンホテル千葉(千葉県千葉市)
    • Year and Date
      2016-06-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] シスプラチン腎症発症予測マーカーとしての尿中メガリン2016

    • Author(s)
      近藤利恵1、各務博、渡部聡、阿部徹哉、細島康宏 、忰田亮平 、小屋俊之 、菊地利明、成田一衛、斎藤亮彦
    • Organizer
      日本内科学会
    • Place of Presentation
      東京国際フォーラム(東京都千代田区)
    • Year and Date
      2016-04-15
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] Critical roles of chemo-resistant effector and regulatory T cells in cancer immunotherapy during hemostatic proliferation2015

    • Author(s)
      Ko Sato, Satoshi Watanabe, Yu Saida, Tomohiro Tanaka, Junko Baba, Aya Ohtsubo, Satoshi Shoji, Daisuke Ishikawa, Rie Kondo, Masaaki Okajima, Satoru Miura, Junta Tanaka, Hiroshi Kagamu, Hirohisa Yoshizawa, Ichiei Narita
    • Organizer
      Annual meeting of american association for cancer research
    • Place of Presentation
      Philadelphia, USA
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09168
  • [Presentation] Circulating small cell lung cancer cells and DDX3X-specific effector T cells in peripheral blood of SCLC patients2015

    • Author(s)
      大坪亜矢、各務博、菊地利明、等
    • Organizer
      日本癌学会総会
    • Place of Presentation
      名古屋国際会議場(名古屋市、愛知県)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked plays oncogenic roles to induce cancer stem cell-like properties2013

    • Author(s)
      Koichiro Nozaki, Hiroshi Kagamu, Satoshi Shoji, Natsue Ikarashi, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, Ichiei Narita
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] DDX3X plays a critical role in a novel EGFR-TKI resistance mechanism correlating with CSC-like properties.2013

    • Author(s)
      Koichiro Nozaki, Hiroshi Kagamu, Jun Koshio, Kosuke Ichikawa, Yu Saida, Tomohiro Tanaka, Satoshi Watanabe, Hirohisa Yoshizawa, and Ichiei Narita
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked plays an oncogenic roles to induce cancer stem cell-like properties2012

    • Author(s)
      Koichiro Nozaki1, Hiroshi Kagamu1, Yu Saida1, Tomohiro Tanaka1, Satoshi Watanabe2, Hirohisa Yoshizawa2, and Ichiei Narita1
    • Organizer
      European Society for Medical Oncology
    • Place of Presentation
      Vienna, Austria
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] Successful treatment of advanced tumors with chemo-immunotherapy : a combination of cyclophosphamide and inhibition of chemo-resistant immune suppressor cells2012

    • Author(s)
      才田優、渡部聡、田中知宏、馬場順子、市川紘将、古塩純、田中純太、各務博、吉澤弘久、成田一衛
    • Organizer
      American association of cancer research
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Oncogenic roles of DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked2012

    • Author(s)
      Koichiro Nozaki1, Hiroshi Kagamu1, Yu Saida1, Tomohiro Tanaka1, Satoshi Watanabe2, Hirohisa Yoshizawa2, and Ichiei Narita1
    • Organizer
      日本癌学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] Successful treatment of advanced tumors with chemo-immunotherapy: a combination of cyclophosphamide and inhibition of chemo-resistant immune suppressor cells.2012

    • Author(s)
      Yu Saida, Satoshi Watanabe, Tomohiro Tanaka, Junko Baba, Koichirou Nozaki, Kosuke Ichikawa, Jun Koshio, Satoru Miura, Junta Tanaka, Hiroshi Kagamu, Hirohisa Yoshizawa, Ichiei Narita
    • Organizer
      American assocation of cancer research
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-24591157
  • [Presentation] Combination of cyclophosphamide and inhibition of chemo-resistant suppressor cells successfully treated advanced tumors.2012

    • Author(s)
      Yu Saida, Satoshi Watanabe, Tomohiro Tanaka, Junko Baba, Koichirou Nozaki, Kosuke Ichikawa, Jun Koshio, Satoru Miura, Junta Tanaka, Hiroshi Kagamu, Hirohisa Yoshizawa, Ichiei Narita
    • Organizer
      日本癌学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24591157
  • [Presentation] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is a CD133+ tumor-specific protein and induces antitumor immunity2011

    • Author(s)
      Jun Koshio1, Hiroshi Kagamu1, et al.
    • Organizer
      AACR
    • Place of Presentation
      Orange County convention center (Orland, Florida, USA)
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] Irradiation and reconstitution with in vitro-expanded polyclonal T cells from naive mice augment antitumor response2011

    • Author(s)
      馬場順子、渡部聡、古塩純、市川紘将、田中洋史、田中純太、各務博、吉澤弘久、成田一衛
    • Organizer
      American association for cancer research
    • Place of Presentation
      オーランド(招待講演)
    • Year and Date
      2011-04-04
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is a CD133+ tumor-specific protein and induces antitumor immunity2011

    • Author(s)
      Jun Koshio1, Hiroshi Kagamu1, et al.
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Data Source
      KAKENHI-PROJECT-23591141
  • [Presentation] Irradiation and reconstitution with in vitro-expanded polyclonal T cells from naive mice augments antitumor response2011

    • Author(s)
      馬場順子、渡部聡、才田優、市川紘将、古塩純、田中純太、各務博、吉澤弘久、成田一衛
    • Organizer
      American association of cancer research
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Conditioning for cancer immunotherapy ; ex vivo expanded T cells effectively develop into effectors in lymphopenic hosts2011

    • Author(s)
      才田優、渡部聡、馬場順子、市川紘将、古塩純、田中純太、各務博、吉澤弘久、成田一衛
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Cancer stem cells express specific immunogenic proteins that induce Th17-dominant immunity.2010

    • Author(s)
      古塩純、各務博、市川紘将、馬場順子、宮林貴大、渡部聡、田中洋史、田中純太、吉澤弘久、中田光、成田一衛
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] Chemo-resistant regulatory T cells inhibit the augmentation of antitumor immunity during homeostatic T cell proliferation2010

    • Author(s)
      馬場順子、渡部聡、市川紘将、古塩純、宮林貴大、田中純太、田中洋史、各務博、吉澤弘久、成田一衛
    • Organizer
      American association of cancer research
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Regulatory T cells resistant to cytotoxic regimens prevent antitumor immunity during T cell homeostatic proliferation2010

    • Author(s)
      馬場順子、渡部聡、市川紘将、古塩純、宮林貴大、田中純太、田中洋史、各務博、吉澤弘久、成田一衛
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Cancer stem cells express specific immunogenic proteins that induce Th17-dominant immunity resulting in regression of parental tumor in vivo.2010

    • Author(s)
      Takao Miyabayashi, Hiroshi Kagamu, Jun Koshio, Kosuke Ichikawa, Junko Baba, Satoshi Watanabe, Hiroshi Tanaka, Junta Tanaka, Hirohisa Yoshizawa, Koh Nakata, Ichiei Narita
    • Organizer
      American Association for Cancer Research annual meeting
    • Place of Presentation
      Washington DC
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] Depletion of radio-resistant peripheral regulatory T cells enhances the antitumor immune response during homeostatic proliferation2009

    • Author(s)
      馬場順子、渡部聡、市川紘将、古塩純、宮林貴大、田中純太、田中洋史、各務博、吉澤弘久、成田一衛
    • Organizer
      American association of cancer research
    • Data Source
      KAKENHI-PROJECT-21590984
  • [Presentation] Cancer stem cell targeted immunotherapy mediates potent antitumor reactivity against established parental melanoma.2009

    • Author(s)
      宮林貴大、各務博、小山建一、馬場順子、渡部聡、田中純太、田中洋史、吉澤弘久、中田光、成田一衛
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(intemational session)
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked is a CD133^+ tumor-specific protein and induces antitumor immunity.2009

    • Author(s)
      宮林貴大, 各務博, 小山建一, 栗山英之, 田中純太, 田中洋史, 吉澤弘久, 中田光, 下条文武
    • Organizer
      ECCO 15-34^<th> ESMO Multidisciplinary Congress
    • Place of Presentation
      Berlin
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] Immunotherapy to eliminate cancer stem cells(癌幹細胞根絶をめざした抗腫瘍免疫療法)2008

    • Author(s)
      Takao Miyabayashi, Hiroshi Kagamu. Kenichi Koyama, Takeshi Ota, Hideyuki Kuriyama, Junta Tanaka, Hiroshi Tanaka, Hirohisa Yoshizawa, Fumitake Geiyo
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフイコ横浜
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] Immunotherapy to eliminate cancer stem cells2008

    • Author(s)
      宮林貴大、各務博、小山建一、太田毅、栗山英之、田中純太、田中洋史、吉澤弘久、下条文武
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(oral session)
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] 小細胞肺癌患者末梢血エフェクターCD4+T細胞/制御性T細胞バランスと病期、予後2008

    • Author(s)
      小山建一, 各務博, 田中洋史, 栗山英之, 田中純太, 高田俊範, 吉滓弘久, 下条文武
    • Organizer
      日本呼吸器学会
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2008-06-17
    • Data Source
      KAKENHI-PROJECT-20590915
  • [Presentation] CD4+ effector T cells specific for irrelevant peptides can induce antitumor reactivity via epitope spreading2007

    • Author(s)
      小山建一、各務博
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] CD4+effector T cells specific for irrelevant peptides can induce antitumor reactivity via epitope spreading2007

    • Author(s)
      小山建一、各務博
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] CD4+ effector T cells specific for irrelevant peptides can induce antitumor reactivity via epitope spreading2007

    • Author(s)
      Kenichi, Koyama, Hirohi, Kagamu, et. al.
    • Organizer
      Japanese Cancer Association, annual meeting
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-10-03
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] OVA peptide-responsive CD4^+ effector T cells can induce antitumor immunity via epitope spreading mediated by dendritic cells2007

    • Author(s)
      Kenichi, Koyama, Hiroshi, Kagamu, et. al.
    • Organizer
      American Association for Cancer Research, annual meeting
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2007-04-16
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] OVA peptide-responsive CD4^+ effector T cells can induce antitumor immunity via epitope spreading mediated by dendritic cells2007

    • Author(s)
      小山建一、各務博
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2007-04-16
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] OVA peptide-responsive CD4+effector T cells can induce antitumor immunity via epitope spreading mediated by dendritic cells2007

    • Author(s)
      小山建一、各務博
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      Los Angeles, USA
    • Year and Date
      2007-04-16
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590841
  • [Presentation] DDX3X induces signal switching to stem cell-specific Wnt/β-catenin signaling, resulting in EGFR-TKI resistance in lung cancer cells harboring EGFR activating mutation

    • Author(s)
      Satoshi Shoji, Hiroshi Kagamu, Koichiro Nozaki, Natsue Igarashi, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, and Ichiei Narita
    • Organizer
      American Association for Caner Research annual meeting
    • Place of Presentation
      San Diego Convention Center(San Diego, USA)
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] Critical roles of chemo-resistant effector and regulatory T cells in antitumor immunity after cytotoxic therapy

    • Author(s)
      佐藤昂、渡部聡、才田優、馬場順子、近藤利恵、田中知宏、庄子聡、岡島正明、三浦理、田中純太、各務博、吉澤弘久、成田一衛
    • Organizer
      日本癌学会総会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26670415
  • [Presentation] Intra-tumor heterogeneityに基づくEGFR-TKI初期耐性機序の解明

    • Author(s)
      庄子聡、各務博、大坪亜矢、野嵜幸一郎、岡島正明、三浦理、渡部聡、小屋俊之、成田一衛、菊地利明
    • Organizer
      日本内科学会総会(プレナリーセッション)
    • Place of Presentation
      みやこめっせ(京都市)
    • Year and Date
      2015-04-10 – 2015-04-12
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] DDX3X-specific effector T cells induced in peripheral blood of limited disease-stage small cell lung cancer patients

    • Author(s)
      Natsue Igarashi, Hiroshi Kagamu, Koichiro Nozaki, Satoshi Shoji, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, and Ichiei Narita
    • Organizer
      American Association for Caner Research annual meeting
    • Place of Presentation
      San Diego Convention Center(San Diego, USA)
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] A novel EGFR-TKI resistance mechanism based on intra-tumor heterogeneity

    • Author(s)
      庄子聡、各務博、大坪亜矢、野嵜幸一郎、五十嵐夏恵、岡島正明、三浦理、渡部聡、吉澤弘久、成田一衛
    • Organizer
      日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26293196
  • [Presentation] DDX3X-specific effector T cells induced in peripheral blood of limited disease-stage small cell lung cancer patients

    • Author(s)
      Natsue Igarashi, Hiroshi Kagamu, Koichiro Nozaki, Satoshi Shoji, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, and Ichiei Narita
    • Organizer
      American Association for Caner Research annual meeting
    • Place of Presentation
      San Diego Convention Center, SanDiego, USA
    • Year and Date
      2014-04-05 – 2014-04-09
    • Data Source
      KAKENHI-PROJECT-26670415
  • 1.  NAKATA Koh (80207802)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 12 results
  • 2.  YOSHIZAWA Hirohisa (50282984)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 41 results
  • 3.  WATANABE Satoshi (50529740)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 19 results
  • 4.  TSUCHIDA Masanori (60293221)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TANAKA Hiroshi (80463991)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 6.  MIURA Satoru (70420320)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 7.  Umezu Hajime (50251799)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  Yamaguchi Ou (70795913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  Takuya Maeda (20383763)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  鈴木 穣 (40323646)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  小林 国彦 (30205455)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 12.  解良 恭一 (40400783)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 13.  Nishihara Fuyumi (60406478)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  矢野 聖二 (30294672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  塚田 弘樹 (50323986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  石田 博徳 (70274587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  萩原 弘一 (00240705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  堀本 勝久 (40238803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 19.  才田 優 (90908930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  田中 純太
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAWASAKI Tomonori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  TAKIGUCHI Yuuichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  UMEDA Yukihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  岡島 正明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  毛利 篤人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi