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KOBAYASHI Motomasa  小林 資正

ORCIDConnect your ORCID iD *help
Researcher Number 40116033
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 大阪大学, 薬学研究科, 招へい教授
2017: 大阪大学, 大学院・薬学研究科, 招へい教授
2015 – 2016: 大阪大学, 薬学研究科, 教授
2011 – 2016: 大阪大学, 薬学研究科(研究院), 教授
2015: 大阪大学, 大学院薬学研究科, 教授 … More
2011: 大阪大学, 大学院・薬学研究科, 教授
2007 – 2011: Osaka University, 薬学研究科, 教授
2007 – 2009: Osaka University, 大学院・薬学研究科, 教授
2006: 大阪大学, 大学院薬学研究科, 教授
2004 – 2005: Osaka University, Graduate School of Pharmaceutical Sciences, Professor, 大学院・薬学研究科, 教授
1998 – 2005: Faculty of Pharmaceutical Sciences, Osaka University, Professor, 薬学研究科, 教授
1995 – 1997: 大阪大学, 薬学部, 教授
1992 – 1995: Osaka University Faculty of Pharmaceutical Sciences Associate Professor, 薬学部, 助教授
1990 – 1991: 大阪大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Chemical pharmacy / Living organism molecular science / Science and Engineering / Biomolecular chemistry / Environmental pharmacy / Bioorganic chemistry / 医薬分子機能学 / Science and Engineering / Chemical pharmacy
Except Principal Investigator
Chemical pharmacy … More / Living organism molecular science / Natural medicines / Biomolecular chemistry / Science and Engineering / Science and Engineering Less
Keywords
Principal Investigator
海洋生物 / 海綿 / 細胞毒性 / インドネシア / 医薬資源 / agosterol A / Indonesia / 生物活性 / marine sponge / 抗がん剤 … More / 海洋微生物 / P-glycoprotein / デプシペプチド / Biological active / Marine sponge / 生物活性物質 / 標的分子 / 分化誘導物質 / 細胞毒性物質 / callystatin A / ニガキ科植物 / Brucea javanica / 鴉胆子 / カシノイド / 抗マラリア剤 / がん多剤耐性 / 抗腫瘍性 / マクロリド / 細胞周期制御 / MRP / araguspongine / arenastatin A / がん多剤耐性克服物質 / Marine resource / cytotoxicity / 活性天然物 / 医薬シーズ / 血管新生 / 多剤耐性克服物質 / MRP1 / P-gp / ABCトランスポーター / bruceolide / ポリケタイド / 分子標的治療 / 分子標的治療薬 / がん微小環境 / bioactivity / medicinal resource / marine invertebrate / MDR / total synthesis / G1 arrest / photoaffinity probe / multi-drug resistance / cell differentiation / 分子プローブ / 分化誘導 / p21プロモーター遺伝子 / 天然分子プローブ / CDKインヒビター / cell cycle / Anti-tumor / Cell differentiation / 細胞分化誘導 / Marine Invertebrate / KB-CV60 cells / KB-C2 cells / cembrane diterpenes / araguspongines / multidrug resistance associated protein / multidrug resistant tumor cells / Xestospongia属海綿 / glutathione / Spongia属海綿 / multidrug resistance protein / KB-CV60株 / KB-C2株 / センブラン型ジテルペン / araguspongine類 / 多剤耐性がん / depsipeptide / structure activity relationship / polyketide / anti-tumor / 軟サンゴ / 底生海洋生物 / Marine invertebrate / antibiotic activity / marine microorganism / marine organism / bioactive compound / coral life / ビステオネラステロン / テオネラステロン / ステロイドニ量体 / Theonella swinhoei / ポリケチド / ポリアセチレン / サンゴ礁生物 / 抗菌活性 / 生物活性物資 / サンビ礁生物 / プローブ分子 / 標的同定 / 海洋薬物資源 / ケミカルバイオロジー / スクリーニング / 再生医療 / メダカ / 低酸素環境適応 / 微小環境 / 活性物質 / 血管新生阻害 / 低酸素環境 / 血管新来生阻害 / 活性試験 / 分子標的 / 固体培養 / 海洋放線菌 / 神経保護物質 / 個体培養 / 生態機能分子 / p21プロモーター / 細胞周期阻害物質 / 血管新生阻害物質 / 生体機能分子 / 光親和性標識 / カーボネート / コンピュータグラフィックス / leptomycin B / 3,15-di-O-acetylbruceolide / 抗腫性 / 血管内皮細胞 / 抗炎症 / インドネシア薬用植物 / bruceine B / カッシノイド / 細胞間接着抑制 / チューブリン / アレナスタチンA … More
Except Principal Investigator
海綿 / インドネシア / ケミカルバイオロジー / 活性天然物 / folk remedy / medicinal plant / Indonesia / 民間医療 / 薬用植物 / 天然薬物 / 感染症 / 海洋生物 / 細胞毒性 / 複合糖脂質 / folk medicine / Borneo Island / 民間薬 / ボルネオ島 / 抗生物質 / 海洋微生物 / 結核 / 天然物 / 抗腫瘍性 / 海洋細菌 / 群体ホヤ / GM_3 / セラミド / シアル酸 / ガングリオシド / 底生海洋生物 / 海洋薬物資源 / 医薬シーズ / 癌 / がん / 標的分子 / 抗菌物質 / Central kalimantan / スンバワ島 / ロンボク島 / バリ島 / 西ヌサ・テンガラ州 / 中部カリマンタン / East Kalimantan / 西カリマンタン / 東カリマンタン州 / marine sponge / soybean / licorice root Radix / rehmannia root / processing crude drug / bioactive compound / crude drug / naturally occurring drug / 植物プランクトン / 茶 / 甘草 / 地黄 / 生物活性物質 / 修治 / 生薬 / North Sumatera Province / Riau Province / Bengkulu Province / Sumatera Island / naturally occurring drug materials / 北スマトラ州 / リアウ州 / ベンクル州 / スマトラ島 / 分子設計 / 天然物ケミカルバイオロジー / 国際研究者交流(韓国) / 国際研究者交流(中国) / 国際研究者交流(米国) / 異分野融合 / 国際交流(スウェーデン) / 国際交流(韓国) / 国際交流(米国) / 国際交流(ドイツ) / 天然物リガンド / 天然物化学 / 標的同定 / バイオテクノロジー / 大型機器 / 生物有機化学 / 有機合成化学 / プローブ / 各種標識分子 / 稀少活性天然物質 / 生物活性評価系の構築 / 活性天然物質の探索 / 共同研究体制 / 生命現象の解明 / 分子プローブ / 革新的合成反応 / 独創的合成 / 新規反応開発 / 構造決定 / 単離 / 生理活性物質 / 機能解明 / 生理活性 / 生体機能分子 / 全合成 / 紅藻 / 海綿動物 / 海藻 / ホヤ / リ-ド化合物 / 抗腫瘍物質 / マクロリド / デプシペプチド / ステロイド / カルシウムイオン / 生体膜イオン透過能 / イオン輸送能 / イオン補足能 / イオノホア活性 / スフィンゴ糖脂質 / 生体膜 Less
  • Research Projects

    (45 results)
  • Research Products

    (326 results)
  • Co-Researchers

    (65 People)
  •  Exploring new drug targets based on binding protein identification of bioactive natural products

    • Principal Investigator
      ARAI Masayoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Osaka University
  •  Creation of novel molecular-targeted anticancer drugs focused on specific phenotypic changes of cells in tumorPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Osaka University
  •  Investigation of benthic marine organisms in Indonesia and development of new medical resources

    • Principal Investigator
      ARAI Masayoshi
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Natural medicines
    • Research Institution
      Osaka University
  •  Development of short-step synthesis of probe molecules for accelerating target identificationPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Osaka University
  •  Search for bioactive natural products acting at infected region of M. tuberculosis and analysis of their target molecules

    • Principal Investigator
      Arai Masayoshi
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Chemical biology using natural products

    • Principal Investigator
      UEDA Minoru
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  Search for medicinal seeds and analysis of their target moleculesPrincipal Investigator

    • Principal Investigator
      Kobayashi Motomasa
    • Project Period (FY)
      2011 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  Search for molecular-targeted anti-cancer agents acting on the microenvironment in tumor and analysis of their target moleculesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI MOTOMASA
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Establishment of in vivo screening system using Medaka fish toward to the drug discoveryPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  Search for new anti-mycobacterial substances using established assay system focusing on the environments of infected region, and analysis of target molecule for development of new drug targets

    • Principal Investigator
      ARAI Masayoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Investigation of benthonic marine organisms in Indonesia searching for new medicinal seeds.Principal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Search for Bioactive Natural Products for Molecular Target Chemotherapy of CancerPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  生体機能分子の創製の研究統括

    • Principal Investigator
      福山 透
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  海洋生物由来の医薬シーズとしての生体機能分子の探索Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  海洋微生物の固体培養による新規活性物質の探索Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Search for inhibitors of cell cycle and development for natural molecular probePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Investigation of Indonesian Marine Organisms as Medicinal ResourcesPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Osaka University
  •  トランスポーター膜蛋白質の機能解明を目指した活性天然物の探索Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  Search for New Anti-Cancer Seeds Targeting for cell Differentiation and cell CyclePrincipal Investigator

    • Principal Investigator
      KOBAYASI Motomasa
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  トランスポーター膜蛋白質の機能解明を目指した活性天然物の探索Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Science and Engineering
    • Research Institution
      Osaka University
  •  天然カシイノド成分を利用した新規抗マラリア剤の創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Search for Indonesian Marine Life as Medicinal Resource (2)Principal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  天然カシノイドを利用した新規抗マラリア剤の創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  海洋生物を起源とする機能探索分子の探索および創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Search for New Anti-tumor Lead Compounds from Marine OrganismsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Osaka University
  •  Search for Reversing Agents of Multidrug-Resistance in Tumor Cells from Marine OrganismsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Osaka University
  •  新しい抗がん剤の開発を志向する海洋天然物質の探索Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  天然カシノイド成分を利用した新規抗マラリア剤の創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Search for Indonesian Marine Life as Medicinal ResourcePrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  海綿動物由来の抗腫瘍物質の構造と機能Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  水圏生物からの抗腫瘍リ-ド化合物の開発と創製

    • Principal Investigator
      伏谷 伸宏
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  細胞間接着分子に作用する新しい医薬リ-ド化合物の創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  Study on Naturally Occurring Drug Materials in Indonesia-6

    • Principal Investigator
      SHIBUYA Hirotaka
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Fukuyama University
  •  海綿動物由来の抗腫瘍物質の構造と機能Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  水圏生物からの抗腫瘍リ-ド化合物の開発と創製

    • Principal Investigator
      伏谷 伸宏
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  超細胞毒性物質アレナスタチンAをリ-ドとする新規抗腫瘍剤の創製Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  海綿動物由来のマクロリド類の機能と超分子形成Principal Investigator

    • Principal Investigator
      小林 資正
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  生態膜機能性ガングリオシドアナログの合成研究

    • Principal Investigator
      北川 勲
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  水圏生物からの抗腫瘍リ-ド化合物の開発と創製

    • Principal Investigator
      伏谷 伸宏
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Study on Naturally Occurring Drug Materials in Indonesa-5

    • Principal Investigator
      SHIBUYA Hirotaka, 澁谷 博孝, 北川 勲
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Fukuyama University
      Osaka University
  •  生体膜機能性ガングリオシドアナログの合成研究

    • Principal Investigator
      北川 勲
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  生体膜機能性複合糖脂質の合成

    • Principal Investigator
      KITAGAWA Isao
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Pharmacochemical Investigation of Marine Sponge ProductsPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Motomasa
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University
  •  Investigation of Naturally Occurring Drug Materials in Indonesia-3

    • Principal Investigator
      KITAGAWA Isao
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Chemical Investigation of Naturally Occurring Drug Materials. Elucidation of Scientific Basis for Traditional Medicines and Exploitation of New Naturally Occurring Drugs

    • Principal Investigator
      KITAGAWA Isao
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Osaka University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] アルカロイドの科学2017

    • Author(s)
      荒井雅吉, 小林資正
    • Total Pages
      534
    • Publisher
      化学同人
    • ISBN
      9784759814187
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Book] アルカロイドの科学2017

    • Author(s)
      荒井雅吉, 小林資正
    • Total Pages
      534
    • Publisher
      化学同人
    • ISBN
      9784759814187
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Book] Search for New Medicinal Seeds from Marine Organisms. In; Chembiomol ecular Science : at the Frontier of Chemist and Biology2013

    • Author(s)
      M, Kobayashi
    • Total Pages
      325
    • Publisher
      Springer-Verlag GmbH
    • Data Source
      KAKENHI-PROJECT-24310159
  • [Book] Search for New Medicinal Seeds from Marine Organisms. In; Chembiomolecular Science: at the Frontier of Chemistry and Biology2013

    • Author(s)
      M. Kobayashi
    • Total Pages
      325
    • Publisher
      Springer-Verlag GmbH
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Book] Chembiomolecular Science: At the Frontier of Chemistry and Biology2013

    • Author(s)
      M. Kobayashi, N. Kotoku, M. Arai
    • Total Pages
      270
    • Publisher
      Springer-Verlag GmbH, Deutschland
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Book] 天然物化学 -海洋生物編-2008

    • Author(s)
      小林資正共著
    • Publisher
      (株)アイピーシー
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Book] 天然物化学 -海洋生物編-2008

    • Author(s)
      小林資正
    • Publisher
      (株)アイピ-シ-
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Marine spongean polybrominated diphenyl ethers, selective growth inhibitors against the cancer cells adapted to glucose starvation, inhibits mitochondrial complex II2017

    • Author(s)
      Arai Masayoshi、Shin Dayoung、Kamiya Kentaro、Ishida Ryosuke、Setiawan Andi、Kotoku Naoyuki、Kobayashi Motomasa
    • Journal Title

      Journal of Natural Medicines

      Volume: 71 Issue: 1 Pages: 44-49

    • DOI

      10.1007/s11418-016-1025-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-15H03114, KAKENHI-PROJECT-17H04645
  • [Journal Article] Biakamides A-D, Unique Polyketides from a Marine Sponge, Act as Selective Growth Inhibitors of Tumor Cells Adapted to Nutrient Starvation2017

    • Author(s)
      Naoyuki Kotoku, Ryosuke Ishida, Hirokazu Matsumoto, Masayoshi Arai, Kazunari Toda, Andi Setiawan, Osamu Muraoka, and Motomasa Kobayashi
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 82 Issue: 3 Pages: 1705-1718

    • DOI

      10.1021/acs.joc.6b02948

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07996, KAKENHI-PROJECT-16K08313, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-15H03114, KAKENHI-PROJECT-17H04645
  • [Journal Article] Anti-dormant mycobacterial activity of viomellein and xanthomegnin, naphthoquinone dimers produced by marine-derived Aspergillus sp.2017

    • Author(s)
      Kamiya K, Arai M, Setiawan A, Kobayashi M.
    • Journal Title

      Natural Product Communications.

      Volume: 12 Pages: 579-582

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Journal Article] Anti-dormant mycobacterial activity of viomellein and xanthomegnin, naphthoquinone dimers produced by marine-derived Aspergillus sp.2017

    • Author(s)
      K. Kamiya, M. Arai, A. Setiawan, M. Kobayashi
    • Journal Title

      Nat. Prod. Commun.

      Volume: 12 Pages: 579-582

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Journal Article] New 3-alkylpyridine alkaloid, N-methylniphatyne A as an inhibitor of cancer cells adapted to nutrient starvation from an Indonesia marine sponge of Xestospongia sp.2016

    • Author(s)
      Arai, M.; Kamiya, K.; Shin, D.; Matsumoto, H.; Hisa, T.; Setiawan, A.; Kotoku, N.; Kobayashi, M.
    • Journal Title

      Chem. Pharm. Bull.

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Journal Article] Anti-dormant mycobacterial activity and target molecule of melophlins, tetramic acid derivatives isolated from a marine sponge of Melophlus sp.2016

    • Author(s)
      M. Arai, Y. Yamano, K. Kamiya, A. Setiawan, M. Kobayashi
    • Journal Title

      J. Nat. Med.

      Volume: 70 Issue: 3 Pages: 467-475

    • DOI

      10.1007/s11418-016-1005-1

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-15H03114
  • [Journal Article] Furospinosulin-1, marine spongean furanosesterterpene, suppresses the growth of hypoxia-adapted cancer cells by binding to transcriptional regulators p54nrb and LEDGF/p75.2016

    • Author(s)
      Arai, M.; Kawachi, T.; Kotoku, N.; Nakata, C.; Kamada, H.; Tsunoda, S.; Tsutsumi, Y.; Endo, H.; Inoue, M.; Sato, H.; Kobayashi, M.
    • Journal Title

      ChemBioChem

      Volume: 17 Issue: 2 Pages: 181-189

    • DOI

      10.1002/cbic.201500519

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25461937, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-26305002
  • [Journal Article] <i>N</i>-Methylniphatyne A, a New 3-Alkylpyridine Alkaloid as an Inhibitor of the Cancer Cells Adapted to Nutrient Starvation, from an Indonesian Marine Sponge of <i>Xestospongia</i> sp.2016

    • Author(s)
      M. Arai, K. Kamiya, D. Shin, H. Matsumoto, T. Hisa, A. Setiawan, N. Kotoku, M. Kobayashi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 64 Issue: 7 Pages: 766-771

    • DOI

      10.1248/cpb.c16-00118

    • NAID

      130005160059

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-15H03114
  • [Journal Article] New 3-alkylpyridine alkaloid, N-methylniphatyne A as an inhibitor of cancer cells adapted to nutrient starvation from an Indonesia marine sponge of Xestospongia sp.2016

    • Author(s)
      Arai, M.; Kamiya, K.; Shin, D.; Matsumoto, H.; Hisa, T.; Setiawan, A.; Kotoku, N.; Kobayashi, M.
    • Journal Title

      Chem. Pharm. Bull.

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Journal Article] Search for Anti-angiogenic Substances from Natural Sources2016

    • Author(s)
      Kotoku, N.; Arai, M.; Kobayashi, M.
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 64 Issue: 2 Pages: 128-134

    • DOI

      10.1248/cpb.c15-00744

    • NAID

      130005121723

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-15H03114
  • [Journal Article] Enantioselective synthesis of dictyoceratin-A (smenospondiol) and -C, hypoxia-selective growth inhibitors from marine sponge2015

    • Author(s)
      Yuji Sumii, Naoyuki Kotoku, Akinori Fukuda, Takashi Kawachi, Yuta Sumii, Masayoshi Arai, Motomasa Kobayashi
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 23 Issue: 5 Pages: 966-975

    • DOI

      10.1016/j.bmc.2015.01.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26860065, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-15H03114
  • [Journal Article] Structure-activity relationship and in vivo anti-tumor evaluation of dictyoceratin-A and -C, hypoxia-selective growth inhibitors from marine sponge.2015

    • Author(s)
      Sumii, Y.; Kotoku, N.; Fukuda, A.; Kawachi, T.; Sumii, Y.; Arai, M.; Kobayashi, M.
    • Journal Title

      Marine Drugs

      Volume: 13 Issue: 12 Pages: 7419-7432

    • DOI

      10.3390/md13127074

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26860065, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-15H03114
  • [Journal Article] Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp.2015

    • Author(s)
      Arai, M.; Kamiya, K.; Pruksakorn, P.; Sumii, Y.; Kotoku, N.; Joubert, J.-P.; Moodley, P.; Han, C.; Shin, D.; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 23 Issue: 13 Pages: 3534-3541

    • DOI

      10.1016/j.bmc.2015.04.033

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-24310159, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-15H03114
  • [Journal Article] Xylarianaphthol-1, a novel dinaphthofuran derivative, activates p21 promoter in a p53-independent manner.2014

    • Author(s)
      N. Kotoku, K. Higashimoto, M. Kurioka, M. Arai, A. Fukuda, Y. Sumii, Y. Sowa, T. Sakai, M. Kobayashi
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 24 Issue: 15 Pages: 3389-3391

    • DOI

      10.1016/j.bmcl.2014.05.083

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26242074
  • [Journal Article] Marine spongian sesquiterpene phenols, dictyoceratin-C and smenospondiol, display hypoxia-selective growth inhibition against cancer cells.2014

    • Author(s)
      M. Arai, T. Kawachi, H. Sato, A. Setiawan, M. Kobayashi
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 24 Issue: 14 Pages: 3155-3157

    • DOI

      10.1016/j.bmcl.2014.04.116

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22241053, KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-26242074
  • [Journal Article] Identification of target protein of agelasine D, a marine spongean diterpene alkaloid, as an anti-dormant mycobacterial substance.2014

    • Author(s)
      M. Arai, Y. Yamano, A. Setiawan, M. Kobayashi
    • Journal Title

      ChemBioChem

      Volume: 15 Issue: 1 Pages: 117-123

    • DOI

      10.1002/cbic.201300470

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-24310159
  • [Journal Article] Synthesis and evaluation of effective photoaffinity probe molecule of furospinosulin-1, a hypoxia-selective growth Inhibitor.2014

    • Author(s)
      N. Kotoku, C. Nakata, T. Kawachi, T. Sato, X.H. Guo, A. Ito, Y. Sumii, M. Arai, M. Kobayashi
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 22 Issue: 7 Pages: 2102-2112

    • DOI

      10.1016/j.bmc.2014.02.026

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22241053, KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-25750384, KAKENHI-PROJECT-26242074
  • [Journal Article] Identification of the target protein of agelasine D, a marine sponge diterpene alkaloid, as an anti-dormant mycobacterial substance2014

    • Author(s)
      M. Arai, Y. Yamano, A. Setiawan, M. Kobayashi
    • Journal Title

      Chembiochem

      Volume: 15 Pages: 117-123

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-23102001
  • [Journal Article] Aaptamines, marine spongean alkaloids, as anti-dormant mycobacterial substances.2014

    • Author(s)
      M. Arai, C. Han, Y. Yamano, A. Setiawan M. Kobayashi
    • Journal Title

      J. Nat. Med.

      Volume: 68 Issue: 2 Pages: 372-376

    • DOI

      10.1007/s11418-013-0811-y

    • NAID

      40020023317

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-26305002, KAKENHI-PROJECT-24310159
  • [Journal Article] Marine derived fungal sesterterpenes, ophiobolins, inhibit biofilm formation of Mycobacterium species.2013

    • Author(s)
      M. Arai, H. Niikawa, M. Kobayashi
    • Journal Title

      J. Nat. Med.

      Volume: 67 Issue: 2 Pages: 271-275

    • DOI

      10.1007/s11418-012-0676-5

    • NAID

      40019608927

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-24310159
  • [Journal Article] Synthetic Studies of Cortistatin A Analogue from the CD-Ring Fragment of Vitamin D<sub>2</sub>2013

    • Author(s)
      N. Kotoku, K. Mizushima, S. Tamura, M. Kobayashi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 61 Issue: 10 Pages: 1024-1029

    • DOI

      10.1248/cpb.c13-00375

    • NAID

      130004137256

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-22241053, KAKENHI-PLANNED-23102005, KAKENHI-PROJECT-24790109, KAKENHI-PROJECT-25750384
  • [Journal Article] Creation of Readily Accessible and Orally Active Analogue of Cortistatin A.2012

    • Author(s)
      Kotoku, N.; Sumii, Y.; Hayashi, T.; Tamura, S.: Kawachi, T.; Shiomura, S.; Arai, M.; Kobayashi, M.
    • Journal Title

      ACS Med. Chem. Lett.

      Volume: 3 Issue: 8 Pages: 673-677

    • DOI

      10.1021/ml300143d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053, KAKENHI-PROJECT-24790109, KAKENHI-PLANNED-23102005
  • [Journal Article] Neamphamide B, new cyclic depsipeptide, as an anti-dormant mycobacterial substance from a Japanese marine sponge of Neamphius sp.2012

    • Author(s)
      Yamano, Y,; Arai, M,; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem. Lett.

      Volume: 22 Issue: 14 Pages: 1877-4881

    • DOI

      10.1016/j.bmcl.2012.05.071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053, KAKENHI-PLANNED-23102005
  • [Journal Article] Stylissamide X, a new proline-rich cyclic octapeptide as an inhibitor of cell migration, from an Indonesian marine sponge of Stylissa sp2012

    • Author(s)
      Masayoshi Arai
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 22(4) Issue: 4 Pages: 1818-1821

    • DOI

      10.1016/j.bmcl.2011.10.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002, KAKENHI-PROJECT-22241053, KAKENHI-PROJECT-22659002, KAKENHI-PLANNED-23102005
  • [Journal Article] Anti-angiogenic effect of triterpenoidal saponins from Polygala senega.2011

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      J.Nat.Med.

      Volume: 65 Pages: 149-156

    • NAID

      10029460687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Journal Article] Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium species2011

    • Author(s)
      Ishida S., Arai M., Nikawa H., Kobayashi M.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 34(6) Pages: 917-920

    • NAID

      130000738072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Anti-angiogenic effect of triterpenoidal saponins from Polygala senega.2011

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      J.Nat.Med.

      Volume: 65 Pages: 149-156

    • NAID

      10029460687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium species2011

    • Author(s)
      Ishida S., Arai M., Nikawa H., Kobayashi M.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 34(6) Pages: 917-920

    • NAID

      130000738072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] DedA protein relates to action-mechanism of halicyclamine A, a marine spongean macrocyclic alkaloid, as an anti-dormant mycobacterial substance2011

    • Author(s)
      Arai M., Liu L., Fujimoto T., Setiawan A., Kobayashi M.
    • Journal Title

      Marine Drugs

      Volume: 9(6) Pages: 984-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] DedA protein relates to action-mechanism of halicyclamine A, a marine spongean macrocyclic alkaloid, as an anti-dormant mycobacterial substance2011

    • Author(s)
      Arai M., Liu L., Fujimoto T., Setiawan A., Kobayashi M.
    • Journal Title

      Marine Drugs

      Volume: 9(6) Pages: 984-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Anti-angiogenic effect of triterpenoidal saponins from Polygala senega2011

    • Author(s)
      Arai M., Hayashi A., Sobou M., Ishida S., Kawachi T., Kotoku N., Kobayashi M
    • Journal Title

      J. Nat. Med

      Volume: 65(1) Pages: 149-156

    • NAID

      10029460687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Journal Article] Action-mechanism of trichoderin A, an anti-dormant mycobacterial aminolipopeptide from marine sponge-derived Trichoderma sp2011

    • Author(s)
      Pruksakorn P., Arai M., Liu L., Moodley P., Jacobs Jr. W. R., Kobayashi M.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 34(8) Pages: 1287-1290

    • NAID

      130000936600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Anti-angiogenic effect of triterpenoidal saponins from Polygala senega.2011

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      J.Nat.Med.

      Volume: 65 Pages: 149-156

    • NAID

      10029460687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Journal Article] Action-mechanism of trichoderin A, an anti-dormant mycobacterial aminolipopeptide from marine sponge-derived Trichoderma sp.2011

    • Author(s)
      Pruksakorn P., Arai M., Liu L., Moodley P., Jacobs Jr. W. R., Kobayashi M.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 34(8) Pages: 1287-1290

    • NAID

      130000936600

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Involvement of 14-3-3 Proteins in the Second Epidermal Growth Factor-induced Wave of Rac1 Activation in the Process of Cell Migration2011

    • Author(s)
      Hiroki Kobayashi, Yusuke Ogura, Masato Sawada, Ryoji Nakayama, Kei Takano, Yusuke Minato, Yasushi Takemoto, Etsu Tashiro, Hidenori Watanabe, Masaya Imoto
    • Journal Title

      Journal of Biological Chemistry

      Volume: 286 Issue: 45 Pages: 39259-39268

    • DOI

      10.1074/jbc.m111.255489

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J03194, KAKENHI-ORGANIZER-23102001, KAKENHI-PLANNED-23102010
  • [Journal Article] 海洋生物からの医薬シーズ探索2010

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      有機合成化学協会誌

      Volume: 68巻 Pages: 470-479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Hypoxia-Selective Growth Inhibition of Cancer Cells by Furospinosulin-1, a Furanosesterterpene Isolated from an Indonesian Marine Sponge.2010

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      ChemMedChem

      Volume: 5 Pages: 1919-1926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Journal Article] 海洋生物からの医薬シーズの探索2010

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      有機合成化学協会誌

      Volume: 68 Pages: 470-479

    • NAID

      10026868871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Journal Article] Hypoxia-Selective Growth Inhibition of Cancel Cells by Furospinosulin-1, a Furanosesterterpene Isolated from an Indonesian Marine Sponge.2010

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      ChemMedChem

      Volume: 5 Pages: 1919-1926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Pruksakorn P., Arai M., Kotoku N., Vilcheze C., Baughn A. D., Moodley P., Jacobs Jr. W. R., Kobayashi M.2010

    • Author(s)
      Pruksakorn P., Arai M., Kotoku N., Vilcheze C., Baughn A. D., Moodley P., Jacobs Jr. W. R., Kobayashi M.
    • Journal Title

      Bioorg. Med. Chem. Lett

      Volume: 20(12) Pages: 3658-3663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Probe molecule equipped with boronic acid moiety as a reversible cross-linking group improves its binding affinity2010

    • Author(s)
      Kotoku N., Guo X. H., Arai M., Kobayashi M.
    • Journal Title

      Bioorg. Med. Chem. Lett

      Volume: 20(14) Pages: 4152-4155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] 海洋生物からの医薬シーズの探索2010

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      有機合成化学協会誌

      Volume: 68 Pages: 470-479

    • NAID

      10026868871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Probe molecule equipped with boronic acid moiety as a reversible cross-linking group improves its binding affinity.2010

    • Author(s)
      古徳直之、荒井雅吉、小林資正, ら
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 4152-4155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria2010

    • Author(s)
      Pruksakorn P., Arai M., Kotoku N., Vilcheze C., Baughn A. D., Moodley P., Jacobs Jr. W. R., Kobayashi M.
    • Journal Title

      Bioorg. Med. Chem. Lett

      Volume: 20(12) Pages: 3658-3663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria2010

    • Author(s)
      Patamaporn PRUKSAKORN、荒井雅吉、小林資正, ら
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 3658-3663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Journal Article] Trichoderins, novel aminolippopeptides from a marine sponge-derived Trichoderma sp. are active against dormant mycobacteria2010

    • Author(s)
      Patamaporn PRUKSAKORN、荒井雅吉、小林資正, ら
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 3658-3663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] 海洋生物からの医薬シーズの探索2010

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      有機合成化学協会誌

      Volume: 68 Pages: 470-479

    • NAID

      10026868871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Probe molecule equipped with boronic acid moiety as a reversible cross-linking group improves its binding affinity.2010

    • Author(s)
      古徳直之、小林資正, ら
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 4152-4155

    • Data Source
      KAKENHI-PROJECT-22241053
  • [Journal Article] Hypoxia-Selective Growth Inhibition of Cancer Cells by Furospinosulin-1, a Furanosesterterpene Isolated from an Indonesian Marine Sponge.2010

    • Author(s)
      荒井雅吉、小林資正, ら
    • Journal Title

      ChemMedChem

      Volume: 5 Pages: 1919-1926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Trichoderins, novel aminolipopeptides from a marine sponge-derived Trichoderma sp., are active against dormant mycobacteria2010

    • Author(s)
      Patamaporn PRUKSAKORN、荒井雅吉、小林資正, ら
    • Journal Title

      Bioorg.Med.Chem.Lett.

      Volume: 20 Pages: 3658-3663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] 海洋生物からの医薬シーズ探索2010

    • Author(s)
      井雅吉、小林資正
    • Journal Title

      有機合成化学協会誌

      Volume: 68巻 Pages: 470-479

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Hypoxia-selective growth inhibition of cancer cells by furospinosulin-1, a furanosesterterpene isolated from an Indonesian marine sponge2010

    • Author(s)
      Arai M., Kawachi T., Setiawan A., Kobayashi M.
    • Journal Title

      ChemMedChem

      Volume: 5(11) Pages: 1919-1926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] 海洋天然物のケミカルバイオロジー2009

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      化学と生物

      Volume: 47巻 Pages: 275-282

    • NAID

      10026435290

    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] New Rev-export inhibitor from Alpinia galanga and structure-activity relationship.2009

    • Author(s)
      Tamura, S.; Shiomi, A.; Kameko, M.; Ye, Y.; Yoshida, M.; Yoshikawa, M.; Kimura, T.; Kobayashi, M.; Murakami, N.
    • Journal Title

      Bioorg.Med.Chem.Lett. 19

      Pages: 2555-2557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death.2009

    • Author(s)
      Suna, H.; Arai, M.; Tsubotani, Y.; Hayashi, A.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 3968-3972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Pyripyropenes, fungal sesquiterpenes conjugated with α-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.2009

    • Author(s)
      Hayashi, A.; Arai, M.; Fujita, M.; Kobayashi, M.
    • Journal Title

      Biol.Pharm.Bull.

      Volume: 32 Pages: 1261-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death.2009

    • Author(s)
      Suna, H.; Arai, M.; Tsubotani, Y.; Hayashim, A.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Bioorg.Med.Chem. 17

      Pages: 3968-3972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Pyripyropenes, fungal sesquiterpenes conjugated with.-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells2009

    • Author(s)
      Hayashi A., Arai M., Fujita M., Kobayashi M.
    • Journal Title

      Biol. Pharm. Bull

      Volume: 32(7) Pages: 1261-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Pyripyropenes, fungal sesquiterpenes conjugated withα-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.2009

    • Author(s)
      Hayashi, A. ; Arai, M. ; Fujita, M. ; Kobayashi, M.
    • Journal Title

      Biol. Pharm. Bull 32

      Pages: 1261-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death2009

    • Author(s)
      Suna H., Arai M., Tsubotani Y., Hayashi A., Setiawan A., Kobayashi M.
    • Journal Title

      Bioorg. Med. Chem

      Volume: 17(11) Pages: 3968-3972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp2009

    • Author(s)
      Arai M., Ishida S., Setiawan A., Kobayashi M.
    • Journal Title

      Chem. Pharm. Bull

      Volume: 57(10) Pages: 1136-1138

    • NAID

      130000124793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp.2009

    • Author(s)
      Arai, M.; Ishida, S.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Chem.Pharm.Bull. 57

      Pages: 1136-1138

    • NAID

      130000124793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp.2009

    • Author(s)
      Arai, M.; Ishida, S.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Chem.Pharm.Bull.

      Volume: 57 Pages: 1136-1138

    • NAID

      130000124793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Pyripyropenes, fungal sesquiterpenes conjugated with α-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.2009

    • Author(s)
      Hayashi, A.; Arai, M.; Fujita, M.; Kobayashi, M.
    • Journal Title

      Biol.Pharm.Bull. 32

      Pages: 1261-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] New Rev-export inhibitor from Alpinia galanga and structure-activity relationship.2009

    • Author(s)
      Tamura, S.; Shiomi, A.; Kaneko, M.; Ye, Y.; Yoshida, M.; Yoshikawa, M.; Kimura, T.; Kobayashi, M.; Murakami, N.
    • Journal Title

      Bioorg.Med.Chem.Lett. 19

      Pages: 2555-2557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Pyripyropenes, fungal sesquiterpenes conjugated with α-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells.2009

    • Author(s)
      Hayashi, A.; Arai, M.; FUJITA, M.; Kobayashi, M.
    • Journal Title

      Biol.Pharm.Bull. 32

      Pages: 1261-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death.2009

    • Author(s)
      Suna, H.; Arai, M.; Tsubotani, Y.; Hayashi, A.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Bioorg.Med.Chem.

      Volume: 17 Pages: 3968-3972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] 海洋天然物のケミカルバイオロジー2009

    • Author(s)
      荒坦雅吉、小林資正
    • Journal Title

      化学と生物 47

      Pages: 275-282

    • NAID

      10026435290

    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Haliconacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Hliclona sp.2009

    • Author(s)
      Arai, M.; Ishida, S.; Setiawan, A.; Kobayashi, M.
    • Journal Title

      Chem.Pharm.Bull. 57

      Pages: 1136-1138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Haliclonacyclamines, tetracyclic alkylpiperidine alkaloids, as anti-dormant mycobacterial substances from a marine sponge of Haliclona sp2009

    • Author(s)
      Arai M., Ishida S., Setiawan A., Kobayashi M.
    • Journal Title

      Chem. Pharm. Bull

      Volume: 57(10) Pages: 1136-1138

    • NAID

      130000124793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Journal Article] Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death.2009

    • Author(s)
      Suna, H. ; Arai, M. ; Tsubotani, Y. ; Hayashi, A. ; Setiawan, A. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem 17

      Pages: 3968-3972

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] 海洋天然物のケミカルバイオロジー2009

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      化学と生物 47

      Pages: 275-282

    • NAID

      10026435290

    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] 海洋天然物のケミカルバイオロジー2009

    • Author(s)
      荒井雅吉、小林資正
    • Journal Title

      化学と生物47巻化学と生物

      Volume: 47巻 Pages: 275-282

    • NAID

      10026435290

    • Data Source
      KAKENHI-PROJECT-21406002
  • [Journal Article] Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge.2008

    • Author(s)
      Kotoku, N. ; Hiramatsu, A. ; Tsujita, H. ; Hirakawa, Y. ; Sanagawa, M. ; Aoki, S. ; Kobayashi, M.
    • Journal Title

      Arch. Pharm. (Weinheim) 341

      Pages: 568-577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells.2008

    • Author(s)
      Kong, D. ; Aoki, S. ; Sowa, Y. ; Sakai, T. ; Kobayashi, M.
    • Journal Title

      Marine Drugs 6

      Pages: 480-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Synthesis of CD-ring structure of cortistatin A, an antiangiogenic steroidal alkaloid from marine sponge2008

    • Author(s)
      Kotoku, N., Sumii, Y., Hayashi, T., Kobayashi, M.
    • Journal Title

      Tetrahed. Lett. 49

      Pages: 7078-7081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Structure-activity relationships study of bastadin 6, an antiangiogenic brominated-tyrosine derived metabolite from marine sponge2008

    • Author(s)
      Kotoku, N. ; Hiramatsu, A. ; Tsujita, H. ; Hirakawa, Y. ; Sanagawa, M. ; Aoki, S. ; Kobayashi, M.
    • Journal Title

      Arch. Pharm. (Weinheim) 341

      Pages: 568-577

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Synthesis of BC-ring model of globostellatic acid X methyl ester, an anti-angiogenic substance from marine sponge.2008

    • Author(s)
      Kotoku, N. ; Tamada, N. ; Hayashi, A. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem. Lett 18

      Pages: 3532-3535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Synthesis of CD-ring structure of cortistatin A, an anti-angiogenic steroidal alkaloid from marine sponge.2008

    • Author(s)
      Kotoku, N. ; Sumii, Y. ; Hayashi, T. ; Kobayashi, M.
    • Journal Title

      Tetrahed. Lett 49

      Pages: 7078-7081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Synthesis of BC-ring model of globostellatic acid X methyl ester, an antiangiogenic substance from marine sponge2008

    • Author(s)
      Kotoku, N. ; Tamada, N. ; Hayashi, A. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem. Lett. 18

      Pages: 3532-3535

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Novel isomarabarican triterpenes, exhibiting selective anti-proliferative activity against vascular endothelial cells, from marine sponge Rhabdastrella globostellata.2007

    • Author(s)
      Aoki, S. ; Sanagawa, M. ; Watanabe, Y. ; Setiawan, A. ; Arai, M. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem 15

      Pages: 4818-4828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids2007

    • Author(s)
      Aoki, S. ; Watanabe, Y. ; Tanabe, D. ; Arai, M. ; Suna, H. ; Miyamoto, K. ; Tsujibo, H. ; Tsujikawa, K. ; Yamamoto, H. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem. 15

      Pages: 6758-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Novel isomarabarican triterpenes, exhibiting selective antiproliferative activity against vascular endothelial cells, from marine sponge Rhabdastrella globostellata2007

    • Author(s)
      Aoki, S. ; Sanagawa, M. ; Watanabe, Y. ; Setiawan, A. ; Arai, M. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem. 15

      Pages: 4818-4828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids.2007

    • Author(s)
      Aoki, S. ; Watanabe, Y. ; Tanabe, D. ; Arai, M. ; Suna, H. ; Miyamoto, K. ; Tsujibo, H. ; Tsujikawa, K. ; Yamamoto, H. ; Kobayashi, M.
    • Journal Title

      Bioorg. Med. Chem 15

      Pages: 6758-6762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner2006

    • Author(s)
      Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A, Kobayashi M
    • Journal Title

      BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 342

      Pages: 101-106

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Cortistatin A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex2006

    • Author(s)
      Aoki, S. ; Watanabe, Y. ; Sanagawa, M. ; Setiawan, A. ; Kotoku, N. ; Kobayashi, M.
    • Journal Title

      J. Ame. Chem. Soc. 128

      Pages: 3148-3149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Cortistatin A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex.2006

    • Author(s)
      Aoki, S. ; Watanabe, Y. ; Sanagawa, M. ; Setiawan, A. ; Kotoku, N. ; Kobayashi, M.
    • Journal Title

      J. Am. Chem. Soc 128

      Pages: 3148-3149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Journal Article] Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells2006

    • Author(s)
      Aoki S, Cho S-H, Ono M, Kuwano T, Nakao S, Kuwano M, Nakagawa S, Gao JQ, Mayumi T, Shibuya M, Kobayashi M
    • Journal Title

      ANTI-CANCER DRUGS 17

      Pages: 269-278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Cortistatins A, B, C, and D, anti-angiogenic steroidal alkaloids, from the marine sponge Corticium simplex2006

    • Author(s)
      Aoki S, Watanabe Y, Sanagawa M, Setiawan A, Kotoku N, Kobayashi M
    • Journal Title

      JOURNAL OF AMERICAN CHEMICAL SOCIETY 128

      Pages: 3148-3149

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Absolute stereo-structure of kendarimide A, a novel MDR modulator, from a marine sponge2005

    • Author(s)
      Kotoku N, Cao LW, Aoki S, Kobayashi M
    • Journal Title

      HETEROCYCLES 65

      Pages: 563-578

    • NAID

      40006650944

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] MRP1 mutated in the L-0 region transports SN-38 but not leukotriene C-4 or estradiol-17 (beta-D-glucuronate)2005

    • Author(s)
      Noguchi T, Ren XQ, Aoki S, Igarashi Y, Che XF, Nakajima Y, Takahashi H, Mitsuo R, Tsujikawa K, Sumizawa T, Haraguchi M, Kobayashi M, Goto S, Kanehisa M, Aikou T, Akiyama S, Furukawa T
    • Journal Title

      BIOCHEMICAL PHARMACOLOGY 70

      Pages: 1056-1065

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] GSH inhibits trypsinization of the C-terminal half of human MRP12005

    • Author(s)
      Ren XQ, Furukawa T, Nakajima Y, Takahashi H, Aoki S, Sumizawa T, Haraguch M, Kobayashi M, Chijiiwa K, Akiyama S
    • Journal Title

      JOURNAL OF BIOLOGICAL CHEMISTRY 280

      Pages: 6231-6237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF102005

    • Author(s)
      Wei H, Itoh T, Kinoshita M, Kotoku N, Aoki S, Kobayashi M
    • Journal Title

      TETRAHEDRON 61

      Pages: 8054-8058

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona2004

    • Author(s)
      S.Aoki, M.Kobayashi et al.
    • Journal Title

      TETRAHEDRON 60

      Pages: 7053-7059

    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells2004

    • Author(s)
      Aoki S, Kong D, Matsui H, Rachmat R, Kobayashi M
    • Journal Title

      CHEM.PHARM.BULL. 52

      Pages: 935-937

    • NAID

      110003615689

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp.2004

    • Author(s)
      S.Aoki, LW.Gao, K.Matsui, R.Rachmat, S.Akiyama, M.Kobayashi
    • Journal Title

      Tetrahedron 60

      Pages: 7053-7059

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF102004

    • Author(s)
      Wei H, M.Kobayashi et al.
    • Journal Title

      TETRAHEDRON 60

      Pages: 6015-6019

    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Erythroid differentiation in K562 myelogenous cells induced by crambescidin 800, a pentacyclic guanidine alkaloid2004

    • Author(s)
      Aoki S, Kong D, Matsui H, Kobayashi M
    • Journal Title

      ANTICANCER RESEARCH 24

      Pages: 2325-2330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Function of the ABC signature sequences in the human multidrug resistance protein 12004

    • Author(s)
      Ren XQ, Furukawa T, Haraguchi M, Sumizawa T, Aoki S, Kobayashi M, Akiyama S
    • Journal Title

      MOLECULAR PHARMACOLOGY 65

      Pages: 1536-1542

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Erythroid differentiation in K562 chronic myelogenous cell sinduced by crambescidin 800, a pentacyclic guanidine alkaloid.2004

    • Author(s)
      S.Aoki, D.Kong, K.Matsui, M.Kobayashi
    • Journal Title

      Anticancer Res. 24

      Pages: 2325-2330

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsipeptide, with anti-tumor activity2004

    • Author(s)
      Murakami N, Tamura S, Koyama K, Sugimoto M, Maekawa R, Kobayashi M
    • Journal Title

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14

      Pages: 2597-2601

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Smenospongine, a spongean sesquiterpene aminoquinone, induces erythroid differentiation in K562 cells.2004

    • Author(s)
      S.Aoki, M.Kobayashi et al.
    • Journal Title

      ANTI-CANCER DRUGS 15

      Pages: 363-369

    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Smenospongine, a spongean sesquiterpene aminoquinone, induces erythroid differentiation in K562 cells2004

    • Author(s)
      Aoki S, Kong D, Matsui K, Kobayashi M
    • Journal Title

      ANTI-CANCER DRUGS 15

      Pages: 363-369

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Cytotoxic sesquiterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10.2004

    • Author(s)
      Wei H, Itoh T, Kinoshita K, Nakai Y, Kurotaki M, Kobayashi M
    • Journal Title

      TETRAHEDRON 60

      Pages: 6015-6019

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] New analogue of arenastatin A, a potent cytotoxic spongean depsi peptide, with anti-tumor activity.2004

    • Author(s)
      N.Murakami, S.Tamura, K.Koyama, M.Sugimoto, R.Maekawa, M.Kobayashi
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 2597-2601

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxides.2004

    • Author(s)
      N.Murakami, M.Kawanishi, S.Itagaki, T.Horii, M.Kobayashi
    • Journal Title

      Bioorg.Med.Ghem.Lett. 14

      Pages: 3513-3516

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Function of the ABC signature sequences in the human multidrug resistance protein 1.2004

    • Author(s)
      XQ.Ren, T.Furukawa, M.Haraguchi, T.Sumizawa, S.Aoki, M.Kobayashi, S.Akiyama
    • Journal Title

      Mol.Pharmacol. 65

      Pages: 1536-1542

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure2004

    • Author(s)
      Kawanishi M, Kotoku N, Itagaki S, Horii T, Kobayashi M
    • Journal Title

      BIOORGANIC & MEDICINAL CHEMISTRY 12

      Pages: 5297-5307

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Smenospongine, a spongean sesquiterpene aminoquinone, induces crythroid differentiation in K562 cells.2004

    • Author(s)
      S.Aoki, D.Kong, K.Matsui, M.Kobayashi
    • Journal Title

      ANTI-CANCER DRUGS. 15

      Pages: 363-369

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Synthesis of a bioprobe for elucidation of target molecule of spongean anti-malarial peroxides2004

    • Author(s)
      Murakami N, Kawanishi M, Itagaki S, Horii T, Kobayashi M
    • Journal Title

      BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14

      Pages: 3513-3516

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Sesquiterpene aminoquinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells.2004

    • Author(s)
      S.Aoki, M.Kobayashi et al.
    • Journal Title

      Chem.Pharm.Bull. 52

      Pages: 935-937

    • NAID

      110003615689

    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp.2004

    • Author(s)
      Aoki S, Cao L, Matsui K, Rachmat R, Akiyama S, Kobayashi M
    • Journal Title

      TETRAHEDRON 60

      Pages: 7053-7059

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Sesquiterpene amino quinones, from a marine sponge, induce erythroid differentiation in human chronic myelogenous leukemia, K562 cells.2004

    • Author(s)
      S.Aoki, D.Kong, K.Matsui, R.Rachmat, M.Kobayashi
    • Journal Title

      Chem.Pharm.Bull. 52

      Pages: 935-937

    • NAID

      110003615689

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10.2004

    • Author(s)
      H.Wei, T.Ito, M.Kinoshita, Y.Nakai, M.Kurotaki, M.Kobayashi
    • Journal Title

      Tetrahedron 60

      Pages: 6015-6019

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis2003

    • Author(s)
      Aoki S, Wei H, Matsui K, Rachmat R, Kobayashi M
    • Journal Title

      BIOORGANIC MEDICINAL CHEMISTRY 11

      Pages: 1969-1973

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Komodoquinone A, a novel neuritogenic anthracycline, from marine Streptomyces sp.KS32003

    • Author(s)
      Itoh T, Kinoshita M, Aoki S, Kobayashi M
    • Journal Title

      J.NATURAL PRODUCTS 66

      Pages: 1373-1377

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] New semisynthetic quassinoids with in vivo antimalarial activity.2003

    • Author(s)
      N.Murakami, M.Sugimoto, M.Kawanishi, S.Tamura, H-S, Kim, K.Begum, Y.Wataya, M.Kobayashi
    • Journal Title

      J.Med.Chem. 46

      Pages: 638-641

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Malformation of immature starfish oocytes by theonellapeptolide Ie, a tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution.2003

    • Author(s)
      E.Ohta, H.Okada, S.Ohta, M.Kobayashi, 以下6名(4番目)
    • Journal Title

      Biosci.Biotechnol.Biochem. 67

      Pages: 1908-1915

    • NAID

      110002694326

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Stereostructure of komodoquinone A, a neuritogenic anthracycline, from marine Streptomyces sp.KS32003

    • Author(s)
      Itoh T, Kinoshita M, Wei H, Kobayashi M
    • Journal Title

      CHEM.PHARM.BULL. 51

      Pages: 1402-1404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] New semisynthetic quassinoids with in vivo antimalarial activity2003

    • Author(s)
      Murakami N, Sugimoto M, Kawanishi M, Tamura S, Kim H.-S, Begum K, Wataya Y, Kobayashi M
    • Journal Title

      J.MEDICINAL CHEMISTRY 46

      Pages: 638-641

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] In situ photoaffinity labeling of the target protein for lembehyne A, a neuronal differentiation inducer2003

    • Author(s)
      Aoki S, Matsui K, Takata T, Kobayashi M
    • Journal Title

      FEBS LETTERS 544

      Pages: 223-227

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] New anti-malarial peroxides with in vivo potency derived from spongean metabolites2003

    • Author(s)
      Murakami N, Kawanishi M, Mostaqul H.M, Li J, Itagaki S, Horii T, Kobayashi M
    • Journal Title

      BIOORGANIC MEDICINAL CHEMISTRY LETTERS 13

      Pages: 4081-4084

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Binding site(s) on P-glycoprotein for a newly synthesized photoaffinity analog of agosterol A2003

    • Author(s)
      Mitsuo M, Noguchi T, Nakajima Y, Aoki S, Ren X.-Q, Sumizawa T, Haraguchi M, Kobayashi M, Baba M, Nagata Y, Akiyama S, Furukawa T
    • Journal Title

      ONCOLOGY RESEARCH 14

      Pages: 39-48

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] In situ photoaffinity labeling of the target protein for lembehyne A, a neuronal differentiation inducer.2003

    • Author(s)
      S.Aoki, K.Matsui, T.Takata, M.Kobayashi
    • Journal Title

      FEBS Lett. 544

      Pages: 223-227

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Komodoquinone A, a novel neuritogenic anthracycline, from marine Streptomyces sp.KS3.2003

    • Author(s)
      T.Itoh, M.Kinoshita, S.Aoki, M.Kobayashi
    • Journal Title

      J Nat Prod. 66

      Pages: 1373-1377

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Pyridoacridine alkaloids inducing neuronal differentiation in a neuroblastoma cell line, from marine sponge Biemna fortis.2003

    • Author(s)
      S.Aoki, H.Wei, K.Matsui, R.Rachmat, M.Kobayashi
    • Journal Title

      Bioorg.Med.Chem. 11

      Pages: 1969-1973

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells.2003

    • Author(s)
      M.Mukai, X.F.Che, T.Furukawa, T.Sumizawa, S.Aoki, X.Q.Ren, M.Haraguchi, Y.Sugimoto, M.Kobayashi, H.Takamatsu, S.Akiyama
    • Journal Title

      Cancer Sci. 94

      Pages: 557-563

    • NAID

      10011689584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Reversal of the resistance to STI571 in human chronic myelogenous leukemia K562 cells2003

    • Author(s)
      Mukai M, Che X.-F, Furukawa T, Sumizawa T, Aoki S, Ren X.-Q, Haraguchi M, Sugimoto Y, Kobayashi M, Takamatsu H, Akiyama S
    • Journal Title

      CANCER SCIENCE 94

      Pages: 557-563

    • NAID

      10011689584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP12003

    • Author(s)
      Ren X-Q, Furukawa T, Aoki S, Sumizawa T, Haraguchi M, Che X.-F, Kobayashi M, Akiyama S
    • Journal Title

      BRITISH J.PHARMACOLOGY 138

      Pages: 1553-1561

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] New anti-malarial peroxides with in vivo potency derived from spongean metabolites.2003

    • Author(s)
      N.Murakami, M.Kawanishi, H.M.Mostaqul, J.Li, S.Itagaki, T.Horii, M.Kobayashi
    • Journal Title

      Bioorg.Med.Chem.Lett. 13

      Pages: 4081-4084

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Malformation of immature starfish oocytes by theonellapeptolide Ie, a tridecapeptide lactone from a marine sponge Petrosia species, through disturbance of cortical F-actin distribution2003

    • Author(s)
      Ohta E, Okada H, Ohta S, Kobayashi M, Kitagawa I, Horiike S, Takahashi T, Hosoya H, Yamamoto K, Ikegami S
    • Journal Title

      BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 67

      Pages: 1908-1915

    • NAID

      110002694326

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15406005
  • [Journal Article] Stereostructure of komodoquinone A, a neuritogenic anthracycline, from marine Streptpmyces sp.KS3.2003

    • Author(s)
      T.Itoh, M.Kinoshita, H.Wei, M.Kobayashi
    • Journal Title

      Chemn.Pharm.Bull. 51

      Pages: 1402-1404

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Journal Article] Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.2003

    • Author(s)
      X-Q.Ren, T.Furukawa, S.Aoki, T.Sumizawa, M.Haraguchi, X-F.Che, M.Kobayashi, S.Akiyama
    • Journal Title

      Br.J.Pharmacol. 138

      Pages: 1553-1561

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15310148
  • [Patent] 抗がん物質のスクリーニング方法2012

    • Inventor(s)
      小林資正,荒井雅吉,古徳直之,河内崇志
    • Industrial Property Rights Holder
      小林資正,荒井雅吉,古徳直之,河内崇志
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-184400
    • Filing Date
      2012-08-23
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Patent] 抗がん物質のスクリーニング方法2012

    • Inventor(s)
      小林資正, 荒井雅吉, 古徳直之, 河内崇志
    • Industrial Property Rights Holder
      小林資正, 荒井雅吉, 古徳直之, 河内崇志
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-184400
    • Filing Date
      2012-08-23
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Patent] 新規プレニルアレーン化合物およびその用途2011

    • Inventor(s)
      小林資正、古徳直之、荒井雅吉、河内崇志
    • Industrial Property Rights Holder
      小林資正、古徳直之、荒井雅吉、河内崇志
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-05-06
    • Overseas
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Patent] 新規コルチスタチンA類似体およびその用途2011

    • Inventor(s)
      小林資正、古徳直之、荒井雅吉、田村理
    • Industrial Property Rights Holder
      小林資正、古徳直之、荒井雅吉、田村理
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-09-16
    • Overseas
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Patent] 新規コルチスタチンA類似体およびその用途2010

    • Inventor(s)
      小林資正、古徳直之、荒井雅吉、田村理
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Number
      2010-209131
    • Filing Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Patent] 新規プレニルアレーン化合物およびその用途2010

    • Inventor(s)
      小林資正, 古徳直之, 荒井雅吉, 河内崇志
    • Industrial Property Rights Holder
      国立大学法人大阪大学
    • Industrial Property Number
      2010-107749
    • Filing Date
      2010-05-07
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Patent] 新規プレニルアレーン化合物およびその用途2010

    • Inventor(s)
      小林資正、古徳直之、荒井雅吉、河内崇志
    • Industrial Property Rights Holder
      大阪大学
    • Industrial Property Number
      2010-209131
    • Filing Date
      2010-05-07
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 抗潜在性結核物質 3-(phenethylamino)dimethyl(oxy)aaptamine の構造活性相関研究2017

    • Author(s)
      古徳直之、中村健彦、○野中宏起、山口亜由太、神谷謙太郎、小林資正、荒井雅吉
    • Organizer
      第67回日本薬学会近畿支部大会
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] Structure-activity relationship and mechanistic analysis of biakamides, selective growth inhibitors against cancer cells under nutrient-starved conditions2017

    • Author(s)
      Ryosuke Ishida, Naoyuki Kotoku, Hirokazu Matsumoto, Sayaka Ichii, Motomasa Kobayashi, Masayoshi Arai
    • Organizer
      10th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences For Young Scientists
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] Effect of new marine spongian diterpenes, ceylonamides G-I, on cancer cell spheroid.2017

    • Author(s)
      ○Takahiro Jomori, Andi Setiawan, Motomasa Kobayashi, Masayoshi Arai
    • Organizer
      The 10th Seoul-Kyoto-Osaka Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 海綿由来ブロモフェノール類のグルコース飢餓環境選択的増殖阻害活性と作用メカニズム解析2017

    • Author(s)
      古徳直之,申多英,石田良典,松本紘和,久智也,戸田和成,荒井雅吉,小林資正
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター等(宮城県仙台市)
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 海洋由来微生物が産生する栄養飢餓環境適応がん細胞増殖阻害物質の探索2017

    • Author(s)
      ○石田 良典、唐 睿、木村 出海、小林 資正、荒井 雅吉
    • Organizer
      第67回日本薬学会近畿支部大会
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] Structure-activity relationship and mechanistic analysis of biakamides, selective growth inhibitors against cancer cells under nutrient-starved conditions.2017

    • Author(s)
      ○Ryosuke Ishida, Naoyuki Kotoku, Hirokazu Matsumoto, Sayaka Ichii, Motomasa Kobayashi, Masayoshi Arai
    • Organizer
      The 10th Seoul-Kyoto-Osaka Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 海洋由来Trichoderma属真菌からの抗潜在性結核物質の探索2016

    • Author(s)
      荒井雅吉,伊藤みなみ,神谷謙太朗,小林資正
    • Organizer
      日本生薬学会第63年会(富山)
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-09-24
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 海綿由来アルカロイドaaptamine類の潜在性結核菌に対する抗菌活性2016

    • Author(s)
      荒井雅吉,神谷謙太朗,韓智秀,山野 喜,住井裕司,中村健彦,古徳直之,小林資正
    • Organizer
      第66回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪薬科大学(大阪府高槻市)
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 潜在性結核菌に対する抗菌物質nybomycinの標的分子解析2016

    • Author(s)
      荒井雅吉,◯神谷謙太朗,住井裕司,申多英,Patamaporn Pruksakorn,韓智秀,古徳直之,小林資正
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 潜在性結核菌に対する抗菌物質nybomycinの標的分子解析2016

    • Author(s)
      荒井雅吉,◯神谷謙太朗,住井裕司,申多英,Patamaporn Pruksakorn,韓智秀,古徳直之,小林資正
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質dictyoceratin類の標的分子解析2016

    • Author(s)
      古徳直之,荒井雅吉,河内崇志,住井裕司,福田昭典,田中駿,小林資正
    • Organizer
      第58回天然有機化合物討論会
    • Place of Presentation
      東北大学百周年記念会館(宮城県仙台市)
    • Year and Date
      2016-09-14
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 海洋由来Trichoderma属真菌からの抗潜在性結核物質の探索2016

    • Author(s)
      荒井雅吉、○伊藤みなみ、神谷謙太朗、小林資正
    • Organizer
      日本生薬学会第64回年会
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 海洋天然物aaptamine類の潜在性結核菌に対する抗菌活性2016

    • Author(s)
      荒井雅吉,○神谷謙太朗, 韓 智秀, 山野 喜, 住井裕司, 中村健彦, 古徳直之, 小林資正
    • Organizer
      日本生薬学会第64回年会
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質dictyoceratin類の標的分子解析2016

    • Author(s)
      ○古徳直之,荒井雅吉,河内崇志,住井裕司,福田昭典,田中 駿,小林資正
    • Organizer
      第58回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 低栄養選択的がん細胞増殖阻害物質N-methylniphatyne Aの全合成2016

    • Author(s)
      古徳直之,松本紘和,久智也,申多英,山口亞由太,荒井雅吉,小林資正
    • Organizer
      第66回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪薬科大学(大阪府高槻市)
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 医薬シーズの開拓を目指した海洋生物資源からの活性天然物の探索2016

    • Author(s)
      小林資正
    • Organizer
      日本生薬学会第63年会(富山)
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-09-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 低酸素環境選択的増殖阻害物質dictyoceratin類の構造活性相関とin vivo抗腫瘍活性2016

    • Author(s)
      住井裕司, ◯古徳直之,福田昭典,河内崇志,荒井雅吉,小林資正
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 栄養飢餓環境選択的がん細胞増殖阻害物質biakamide類の構造活性相関と作用メカニズム解析2016

    • Author(s)
      石田良典,古徳直之,松本紘和,荒井雅吉,小林資正
    • Organizer
      第21回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      千葉大学薬学部(千葉県千葉市)
    • Year and Date
      2016-10-27
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] Target identification of agelasine D, a marine spongean diterpene alkaloid, as an antidormant mycobacterial substance.2015

    • Author(s)
      Masayoshi Arai, Yoshi Yamano, Andi Setiawan and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル(米国)
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] Anti-dormant mycobacterial activity and action-mechanism of nybomycin produced by Streptomyces sp.2015

    • Author(s)
      ◯Kentaro Kamiya, Masayoshi Arai, Patamaporn Pruksakorn, Yuji Sumii, Naoyuki Kotoku, Chisu Han, Dayoung Shin and Motomasa Kobayashi
    • Organizer
      The 9th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
    • Place of Presentation
      Seoul (Korea)
    • Year and Date
      2015-11-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Target identification of agelasine D, a marine spongean diterpene alkaloid, as an antidormant mycobacterial substance.2015

    • Author(s)
      ◯Masayoshi Arai, Yoshi Yamano, Andi Setiawan and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2015-12-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] Synthetic study and target analysis of dictyoceratin-A and -C, hypoxia-selective growth inhibitors from marine sponge2015

    • Author(s)
      Naoyuki Kotoku, Yuji Sumii, Takashi Kawachi, Akinori Fukuda, Masayoshi Arai and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル(米国)
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 栄養飢餓環境選択的がん細胞増殖阻害物質の探索2015

    • Author(s)
      荒井雅吉,○申多英,松本紘和,神谷謙太朗,久智也,古徳直之,小林資正
    • Organizer
      日本生薬学会第62年会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] グルコース飢餓環境選択的増殖阻害物質biakamide類の構造活性相関研究2015

    • Author(s)
      ◯石田良典,古徳直之,松本紘和,田畑奎太朗,小林資正
    • Organizer
      第65回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪大谷大学(大阪府・富田林市)
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Cortistatin Aアナログ化合物の構造活性相関と標的同定への応用2015

    • Author(s)
      古徳直之、伊藤 葵、◯水野華奈子、渋谷俊一、小林資正
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      デザイン・クリエイティブセンター神戸(神戸)
    • Year and Date
      2015-03-26
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 海綿由来環状デプシペプチドarenastatin Aの新規結合タンパク質の同定2015

    • Author(s)
      ○荒井雅吉,河内崇志,高市伸宏,馬田哲也,古徳直之,小林資正
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール(神奈川県横浜市)
    • Year and Date
      2015-09-09
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 海綿由来環状デプシペプチドarenastatin Aの新規結合タンパク質の同定2015

    • Author(s)
      ◯荒井雅吉,河内崇志,高市伸宏,馬田哲也,古徳直之,小林資正
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール(横浜)
    • Year and Date
      2015-09-09
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] Anti-dormant mycobacterial activity and action-mechanism of nybomycin produced by Streptomyces sp.2015

    • Author(s)
      Kentaro Kamiya, Masayoshi Arai, Patamaporn Pruksakorn, Yuji Sumii, Naoyuki Kotoku, Chisu Han, Dayoung Shin and Motomasa Kobayashi
    • Organizer
      The 9th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists
    • Place of Presentation
      ソウル(韓国)
    • Year and Date
      2015-11-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 海綿由来環状デプシペプチドarenastatin Aの新規結合タンパク質の同定2015

    • Author(s)
      ◯荒井雅吉,河内崇志,高市伸宏,馬田哲也,古徳直之,小林資正
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール(神奈川県・横浜市)
    • Year and Date
      2015-09-09
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Synthetic study and target analysis of dictyoceratin-A and -C, hypoxia-selective growth inhibitors from marine sponge.2015

    • Author(s)
      Naoyuki Kotoku, Yuji Sumii, Takashi Kawachi, Akinori Fukuda, Masayoshi Arai and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      ホノルル(米国)
    • Year and Date
      2015-12-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] グルコース飢餓環境選択的増殖阻害物質biakamide類の構造活性相関研究2015

    • Author(s)
      ○石田良典,古徳直之,松本紘和,田畑奎太朗,小林資正
    • Organizer
      第65回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪大谷大学(大阪府富田林市)
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 低栄養選択的増殖阻害物質fasciospyrinadinoneの全合成2015

    • Author(s)
      古徳直之,松本紘和,久智也,戸田和成,荒井雅吉,小林資正
    • Organizer
      第65回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪大谷大学(大阪府富田林市)
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 底生海洋生物成分からの医薬シーズの探索研究2015

    • Author(s)
      小林資正
    • Organizer
      第50回天然物化学談話会
    • Place of Presentation
      グリーンピア岩沼 モンタナリゾート(宮城県岩沼市)
    • Year and Date
      2015-07-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] Synthetic study and target analysis of dictyoceratin-A and -C, hypoxia-selective growth inhibitors from marine sponge.2015

    • Author(s)
      ◯Naoyuki Kotoku, Yuji Sumii, Takashi Kawachi, Akinori Fukuda, Masayoshi Arai and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2015-12-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] グルコース飢餓環境選択的がん細胞増殖阻害活性を有するポリケチドbiakamide類の全合成と構造活性相関2015

    • Author(s)
      石田良典,古徳直之,松本紘和,荒井雅吉,小林資正
    • Organizer
      第41回反応と合成の進歩シンポジウム
    • Place of Presentation
      近畿大学(大阪府東大阪市)
    • Year and Date
      2015-11-26
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質dictyoceratin-Cの標的分子解析2015

    • Author(s)
      河内崇志,荒井雅吉,古徳直之,小林資正
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質dictyoceratin-Cの標的分子解析2015

    • Author(s)
      ○河内崇志,荒井雅吉,古徳直之,小林資正
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山全日空ホテル(愛媛県松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-15H03114
  • [Presentation] 栄養飢餓環境選択的がん細胞増殖阻害物質の探索2015

    • Author(s)
      荒井雅吉,◯申多英,松本紘和,神谷謙太朗,久智也,古徳直之,小林資正
    • Organizer
      日本生薬学会第62回年会
    • Place of Presentation
      長良川国際会議場(岐阜県・岐阜市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 栄養飢餓環境選択的がん細胞増殖阻害物質の探索2015

    • Author(s)
      荒井雅吉,申多英,松本紘和,神谷謙太朗,久智也,古徳直之,小林資正
    • Organizer
      日本生薬学会第62年会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 低栄養選択的増殖阻害物質fasciospyrinadinoneの全合成2015

    • Author(s)
      古徳直之,松本紘和,◯久智也,戸田和成,荒井雅吉,小林資正
    • Organizer
      第65回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪大谷大学(大阪府・富田林市)
    • Year and Date
      2015-10-17
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質dictyoceratin-Cの標的分子解析2015

    • Author(s)
      ◯河内崇志,荒井雅吉,古徳直之,小林資正
    • Organizer
      第19回日本がん分子標的治療学会学術集会
    • Place of Presentation
      松山全日空ホテル(愛媛県・松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] グルコース飢餓環境選択的がん細胞増殖阻害活性を有するポリケチドbiakamide類の全合成と構造活性相関2015

    • Author(s)
      ◯石田良典,古徳直之,松本紘和,荒井雅吉,小林資正
    • Organizer
      第41回反応と合成の進歩シンポジウム
    • Place of Presentation
      近畿大学(大阪府・東大阪市)
    • Year and Date
      2015-10-26
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Target identification of agelasine D, a marine spongean diterpene alkaloid, as an antidormant mycobacterial substance.2015

    • Author(s)
      ◯Masayoshi Arai, Yoshi Yamano, Andi Setiawan and Motomasa Kobayashi
    • Organizer
      PACIFICHEM 2015
    • Place of Presentation
      Hawaii (USA)
    • Year and Date
      2015-12-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Cortistatin A アナログ化合物の効率的合成法の開発2014

    • Author(s)
      古徳直之、◯渋谷俊一、竹島亜季、角居雄太、伊藤 葵、水野華奈子、小林資正
    • Organizer
      第64回日本薬学会近畿支部総会・大会
    • Place of Presentation
      京都薬科大学(京都)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 海洋由来放線菌が産生するnybomycinの潜在性結核菌に対する抗菌活性とその作用メカニズム2014

    • Author(s)
      ◯神谷謙太朗,住井裕司,申多英,Patamaporn Pruksakorn,韓智秀,古徳直之,小林資正
    • Organizer
      日本生薬学会第61年会
    • Place of Presentation
      福岡大学薬学部(福岡県・福岡市)
    • Year and Date
      2014-09-13
    • Data Source
      KAKENHI-PROJECT-24310159
  • [Presentation] グルコース飢餓環境選択的がん細胞増殖阻害作用を有する新規ポリケチド類の化学構造と生物活性2014

    • Author(s)
      ◯古徳直之,戸田和成,荒井雅吉,石田良典,松本紘和,村岡 修,小林資正
    • Organizer
      第56回天然有機化合物討論会
    • Place of Presentation
      高知県立県民文化ホール(高知)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 低酸素環境選択的細胞増殖阻害活性物質dictyoceratin-Cの合成研究2014

    • Author(s)
      住井裕司、古徳直之、◯福田昭典、河内崇志、角居雄太、荒井雅吉、小林資正
    • Organizer
      第64回日本薬学会近畿支部総会・大会
    • Place of Presentation
      京都薬科大学(京都)
    • Year and Date
      2014-10-11
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 海洋天然物furospinosulin-1を利用する新規がん細胞低酸素適応因子の創出2014

    • Author(s)
      ◯河内崇志,荒井雅吉,古徳直之,小林資正
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      TKPガーデンシティ仙台(仙台)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PROJECT-26242074
  • [Presentation] 潜在性結核菌に有効なジテルペンアルカロイドagelasine Dの結合タンパク質の解明2013

    • Author(s)
      小林 資正
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      北海道
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 新しい医薬シーズの探索と標的分子探索2013

    • Author(s)
      小林 資正
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      北海道
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 潜在性結核菌に有効なジテルペンアルカロイドagelasine Dの結合タンパク質の解明2013

    • Author(s)
      小林 資正
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      北海道
    • Data Source
      KAKENHI-PROJECT-24310159
  • [Presentation] 海綿由来の新しい医薬シーズの探索2012

    • Author(s)
      小林 資正
    • Organizer
      中西シンポジウム2012
    • Place of Presentation
      慶応義塾大学 日吉キャンパス(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来真菌が産生するセスタテルペンophiobolin類のbiofilm形成阻害活性2012

    • Author(s)
      小林資正
    • Organizer
      日本生薬学会 第59回年会
    • Place of Presentation
      かずさアカデミアパーク
    • Year and Date
      2012-09-17
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 海綿由来の新しい医薬シーズの探索2012

    • Author(s)
      小林資正
    • Organizer
      中西シンポジウム2012
    • Place of Presentation
      慶応義塾大学日吉キャンパス(東京)(招待講演)
    • Year and Date
      2012-03-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来の新しい医薬シーズの探索2012

    • Author(s)
      小林資正
    • Organizer
      中西シンポジウム2012
    • Place of Presentation
      慶応義塾大学日吉キャンパス(東京)(招待講演)
    • Year and Date
      2012-03-25
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海綿由来の新しい医薬シーズの探索2012

    • Author(s)
      小林資正
    • Organizer
      中西シンポジウム2012
    • Place of Presentation
      東京
    • Year and Date
      2012-03-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生するセスタテルペンophiobolin類のbiof ilm形成阻害活性2012

    • Author(s)
      小林資正
    • Organizer
      日本生薬学会 第59回年会
    • Place of Presentation
      かずさアカデミアパーク(千葉)
    • Year and Date
      2012-09-17
    • Data Source
      KAKENHI-PROJECT-24310159
  • [Presentation] 腫瘍微小環境で作用する新規抗がん剤の探索2011

    • Author(s)
      荒井雅吉、河内崇志、古徳直之、小林資正
    • Organizer
      第4回食品薬学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-10-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来セスターテルペンheteroneminのbiofilm形成阻害活性2011

    • Author(s)
      石田俊介、荒井雅吉、小林資正, ら
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(グランシップ静岡)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海綿由来抗腫瘍性環状デプシペプチドarenastatin Aの作用機序解明を目指したプローブ分子の合成2011

    • Author(s)
      高市伸宏、古徳直之、小林資正, ら
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(グランシップ静岡)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] Search for New Medicinal Seeds for Cancer Chemotherapy from Marine Organisms2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      Tetrahedron Prize for Creativity in Organic Chemistry Symposium
    • Place of Presentation
      Denver(米国)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質furospinosulin-1の作用メカニズム解析2011

    • Author(s)
      河内崇志、荒井雅吉、小林資正, ら
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(グランシップ静岡)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] Medicinal Seeds for Cancer Chemotherapy from Marine Organisms2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      7th U. S.-Japan Seminar on Marine Natural Products
    • Place of Presentation
      沖縄
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来セスタテルペンheteroneminのbiofilm形成阻害活性2011

    • Author(s)
      韓智秀、荒井雅吉、石田俊介、新川大貴、小林資正
    • Organizer
      日本生薬学会第58回年会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Search for New Medicinal Seeds for Cancer Chemotherapy from Marine Organisms2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      Tetrahedron Prize for Creativity in Organic Chemistry Symposium
    • Place of Presentation
      Denver(米国)(招待講演)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Presentation] 海綿由来セスタテルペンheteroneminのbiofilm形成阻害活性2011

    • Author(s)
      韓智秀、荒井雅吉、石田俊介、新川大貴、小林資正
    • Organizer
      日本生薬学会第58回年会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来血管新生阻害物質cortistatin Aの全合成研究2011

    • Author(s)
      住井裕司、古徳直之、小林資正, ら
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(グランシップ静岡)
    • Year and Date
      2011-03-29
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] インドネシア産海綿由来の新規環状デプシペプチドneamphamide Bの抗潜在性結核活性2011

    • Author(s)
      山野喜、荒井雅吉、小林資正
    • Organizer
      日本生薬学会第58回年会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海綿由来血管新生阻害物質cortistatin Aおよびanalog化合物の合成研究2011

    • Author(s)
      住井裕司、古徳直之、林剛史、田村理、河内崇志、森本薫、荒井雅吉、小林資正
    • Organizer
      第53回天然有機化合物討論会
    • Place of Presentation
      大阪
    • Year and Date
      2011-09-28
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Presentation] 抗潜在性結核物質halicyclamine Aの作用メカニズム解析-ゲノムDNAライブラリーを利用する標的分子の解明-2011

    • Author(s)
      荒井雅吉、Liu Liu、藤本貴男、小林資正
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      兵庫
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Search for New Medicinal Seeds for Cancer Chemotherapy from Marine Organisms2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      Tetrahedron Prize for Creativity in Organic Chemistry Symposium
    • Place of Presentation
      Denver(米国)(招待講演)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] がん転移抑制を指向した細胞接着阻害天然物の探索2011

    • Author(s)
      戸田和成、田村理、荒井雅吉、小林資正
    • Organizer
      第61回日本薬学会近畿支部総会・大会
    • Place of Presentation
      兵庫
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Search for New Medicinal Seeds for Cancer Chemotherapy from Marine Organisms.2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      Tetrahedron Prize for Creativity in Organic Chemistry Symposium
    • Place of Presentation
      Denver(米国)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] インドネシア産海綿由来の新規環状デプシペプチドneamphamide Bの抗潜在性結核活性2011

    • Author(s)
      山野喜、荒井雅吉、小林資正
    • Organizer
      日本生薬学会第58回年会
    • Place of Presentation
      東京
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Medicinal Seeds for Cancer Chemotherapy from Marine Organisms.2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      7th U.S.-Japan Seminar on Marine Natural Products
    • Place of Presentation
      沖縄コンベンションセンター (沖縄)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] Medicinal Seeds for Cancer Chemotherapy from Marine Organisms2011

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      7th U.S.-Japan Seminar on Marine Natural Products
    • Place of Presentation
      沖縄コンベンションセンター(沖縄)(招待講演)
    • Year and Date
      2011-12-12
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 血管新生阻害物質cortistatin Aのアナログ化合物の設計と合成2010

    • Author(s)
      古徳直之、林岡史、森本薫、住井裕司、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都(京都薬科大学)(招待講演)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都(京都薬科大学)(招待講演)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 低酸素環境選択的増殖阻害物質furospinosulin-1のアナログ化合物の合成と作用メカニズム解析2010

    • Author(s)
      古徳直之、荒井雅吉、小林資正, ら
    • Organizer
      第52回天然有機化合物討論会
    • Place of Presentation
      静岡(グランシップ静岡)
    • Year and Date
      2010-09-29
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来微生物からの抗潜在性結核物質の探索2010

    • Author(s)
      荒井雅吉、山野喜、Patamaporn PRUKSAKORN、Ahmed Mohamed MOHAMED、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋由来真菌が生産するセスキテルペンpyripyropene類の血管新生阻害効果2010

    • Author(s)
      林亜紗実、荒井雅吉、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Hypoxia-selective Growth Inhibitor, Furospinosulin-1, from the Marine Sponge Dactylospongia elegans2010

    • Author(s)
      河内崇志、荒井雅吉、小林資正, ら
    • Organizer
      2010 World Pharmaceutical Congress
    • Place of Presentation
      Hilton Philadelphia, Philadelphia(USA)
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] Cell-based assayを基盤とする天然薬物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Presentation] 海洋由来真菌が生するsterigmatocystin類のbiofilm形成阻害活性2010

    • Author(s)
      荒井雅吉、石田俊介、小林資正
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が生産するセスキテルペンpyripyropene類の血管新生阻害効果2010

    • Author(s)
      林亜紗実、荒井雅吉、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 天然薬物資源からの低酸素環境選択的に作用する新規抗がん剤の開発研究2010

    • Author(s)
      小林資正, ら
    • Organizer
      第18回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      東京(北里大学薬学部)
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都(京都薬科大学)(招待講演)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Synthetic Studies of Furospinosulin-1, A Hypoxia-Selective Growth Inhibitor From Marine Sponge2010

    • Author(s)
      古徳直之、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket (Thailand)
    • Year and Date
      2010-10-19
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 生薬Polygala senega由来サポニンsenegin類の血管新生阻害作用2010

    • Author(s)
      河内崇志、荒井雅吉、小林資正, ら
    • Organizer
      第14回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京(タワーホール船堀)
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来放線菌が産生するdesferrioxamine Eのbiofilm形成阻害活性2010

    • Author(s)
      石田俊介、荒井雅吉、小林資正, ら
    • Organizer
      日本生薬学会学会第57回年会
    • Place of Presentation
      徳島(徳島文理大学)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] ANTI-MICROBIAL EFFECT OF MARINE SPONGEAN MACROCYCLIC ALKALOIDS, HALICYCLAMINES, AGAINST DORMANT MYCOBACTERIA AND ANALYSIS OF ITS ACTION MECHANISM2010

    • Author(s)
      石田俊介、荒井雅吉、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket (Thailand)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋由来微生物からの抗潜在性結核物質の探索2010

    • Author(s)
      荒井雅吉、山野喜、Patamaporn PRUKSAKORN、Ahmed Mohamed MOHAMED、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Cell-based assayを基盤とする天然薬物由来の医薬シーズの探索2010

    • Author(s)
      小林資正、古徳直之、荒井雅吉
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] TRICHODERINS, NEW AMINOLIPOPEPTIDES FROM A MARINE SPONGE-DERIVED TRICHODERMA SP, ARE ACTIVE AGAINST DORMANT MYCOBACTERIA2010

    • Author(s)
      山野喜、荒井雅吉、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket(Thailand)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 低酸素環境選択的増殖阻害物質furospinosulin-1の構造活性相関2010

    • Author(s)
      藤岡真一、古徳直之、小林資正, ら
    • Organizer
      第60回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪(摂南大学薬学部)
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] インドネシア産海綿由来の新規環状ペプチドaxinellin Dのがん細胞浸潤阻害作用2010

    • Author(s)
      山野喜、荒井雅吉、藤田真由美、小林資正
    • Organizer
      日本生薬学会第57回年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Synthetic Studies of Cortistatin A, An Anti-Angiogenic Steroidal Alkaloid From Marine Sponge2010

    • Author(s)
      古徳直之、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket (Thailand)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋由来真菌が産生するsterigmatocystin類のbiofilm形成阻害活性2010

    • Author(s)
      荒井雅吉、石田俊介、小林資正
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 血管新生阻害物質cortistatin Aのアナログ化合物の設計と合成2010

    • Author(s)
      古徳直之、林岡史、森本薫、住井裕司、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Cell-based assay基盤とする天然薬物由来の医薬シーズの探索2010

    • Author(s)
      小林資正、古徳直之、芒井雅吉
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] TRICHODERINS, NEW AMINOLIPOPEPTIDES FROM A MARINE SPONGE-DERIVED TRICHODERMA SP., ARE ACTIVE AGAINST DORMANT MYCOBACTERIA2010

    • Author(s)
      Masayoshi Arai, Patamaporn Pruksakorn, Yoshi Yamano, Motomasa Kobayashi
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Phuket(Thailand)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] インドネシア産海綿由来の新規環状ペプチドaxinellin Dのがん細胞浸潤阻害作用2010

    • Author(s)
      山野喜、荒井雅吉、小林資正, ら
    • Organizer
      日本生薬学会学会第57回年会
    • Place of Presentation
      徳島(徳島文理大学)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来放線菌が産生するdesferrioxamine Eのbiofilm形成阻害活性2010

    • Author(s)
      石田俊介、荒井雅吉、小林資正
    • Organizer
      日本生薬学会第57回年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 血管新生阻害物質cortistatin Aの合成研究2010

    • Author(s)
      古徳直之、小林資正, ら
    • Organizer
      第36回反応と合成の進歩シンポジウム
    • Place of Presentation
      名古屋(ウイングあいち)
    • Year and Date
      2010-11-02
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来放線菌が産生するdesferrioxamine Eのbiofilm形成阻害活性2010

    • Author(s)
      石田俊介、荒井雅吉、小林資正
    • Organizer
      日本生薬学会第57回年会
    • Place of Presentation
      徳島
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質furospinosulin-1の作用メカニズムと構造活性相関2010

    • Author(s)
      荒井雅吉、小林資正, ら
    • Organizer
      第29回メディシナルケミストリーシンポジウム
    • Place of Presentation
      京都(京都テルサ)
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] ボロン酸基を捕捉補助基とする新規プローブ分子の合成と機能2010

    • Author(s)
      郭修〓、古徳直之、小林資正, ら
    • Organizer
      第60回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪(摂南大学薬学部)
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋天然物由来の医薬シーズの探索2010

    • Author(s)
      小林資正
    • Organizer
      第27回和漢医薬学会学術大会
    • Place of Presentation
      京都(京都薬科大学)(招待講演)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-22659002
  • [Presentation] CORTISTATINS, NOVEL ANTI-ANGIOGENIC STEROIDAL ALKALOIDS, FROM MARINE SPONGE2010

    • Author(s)
      古徳直之、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket (Thailand)
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] HYPOXIA-SELECTIVE GROWTH INHIBITOR, FUROSPINOSULIN-1, FROM THE MARINE SPONGE DACTYLOSPONGIA ELEGANS2010

    • Author(s)
      荒井雅吉、小林資正, ら
    • Organizer
      The 13th International Symposium on Marine Natural Products
    • Place of Presentation
      Hilton Phuket, Phuket(Thailand)
    • Year and Date
      2010-10-19
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来真菌が産生するsterigmatocystin類のbiofilm形成阻害活性2010

    • Author(s)
      荒井雅吉、石田俊介、小林資正
    • Organizer
      第83回日本細菌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Cell-based assayを基盤とする天然薬物由来の医薬シーズの探索2010

    • Author(s)
      小林資正、古徳直之、荒井雅吉
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] インドネシア産海綿由来の新規環状ペプチドaxinellin Dのがん細胞浸潤阻害作用2010

    • Author(s)
      山野喜、荒井雅吉、小林資正, ら
    • Organizer
      日本生薬学会学会第57回年会
    • Place of Presentation
      徳島(徳島文理大学)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来微生物からの抗潜在性結核物質の探索2010

    • Author(s)
      荒井雅吉、山野喜、Patamaporn PRUKSAKORN、Ahmed Mohamed MOHAMED、小林資正
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来放線菌が産生するdesferrioxamine Eのbiofim形成阻害活性2010

    • Author(s)
      石田俊介、荒井雅吉、小林資正, ら
    • Organizer
      日本生薬学会学会第57回年会
    • Place of Presentation
      徳島(徳島文理大学)
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する新規アミリポペプチドtrichoderin類の抗結核活性2009

    • Author(s)
      Patamaporn Pruksakorn、荒井雅吉、古徳直之、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] インドネシア産海綿由来furospinosulin-1の低酸素環境特異的がん細胞増殖阻害活性2009

    • Author(s)
      荒井雅吉、河内崇志、古徳直之、住井裕司、藤岡真一、小林資正
    • Organizer
      第51回天然有機化合物討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来の大環状アルカロイドhalicyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズムの解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、惣坊真理、小林資正
    • Organizer
      第28回メディシナルケミストリーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-25
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Search for Medicinal Seed from Marine Organisms.2009

    • Author(s)
      Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai
    • Organizer
      The 25th Naito Conference on Chemical Biology [II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 生薬Polygala senega由来サポニンsenegin類の血管新生阻害作用2009

    • Author(s)
      荒井雅吉、林亜紗実、石田俊介、河内崇志、惣坊真理、古徳直之、小林資正
    • Organizer
      第3回食品薬学シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-12
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 生薬Polygala senega由来サポニンsenegin類の血管新生阻害作用2009

    • Author(s)
      荒井雅吉、林亜紗実、石田俊介、河内崇志、惣坊真理、古徳直之、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Hypoxia-selective growth inhibitor, furospinosulin-1, from Indonesian marine sponge2009

    • Author(s)
      Masayoshi Arai, Takashi Kawachi, Naoyuki Kotoku, Yuji Sumii, Motomasa Kobayashi
    • Organizer
      The 25th Naito Conference on Chemical Biology
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海綿由来の大環状アルカロイドhalicyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズムの解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、惣坊真理、小林資正
    • Organizer
      第28回メディシナルケミストリーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-25
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海綿由来の大環状アルカロイドhalicyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズムの解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、惣坊真理、小林資正
    • Organizer
      第28回メディシナルケミストリーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-11-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Search for Medicinal Seed from Marine Organisms2009

    • Author(s)
      Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai
    • Organizer
      The 25th Naito Conference on Chemical Biology[ II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Hypoxia-selective growth inhibitor, furospinosulin-1, from Indonesian marine sponge.2009

    • Author(s)
      Masayoshi Arai, Takashi Kawachi, Naoyuki kotoku, Yuji Sumii, motomasa Kobayashi
    • Organizer
      The 25th Naito Conference on Chemical Biology[II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋生物成分からの新しい抗がん剤シーズ探索2009

    • Author(s)
      荒井雅吉、古徳直之、小林資正
    • Organizer
      近畿大学薬学総合研究所・大学院薬学研究科、文部科学省私立大学学術高度化推進事業、ハイテク・リサーチ・センター整備事業 第5回シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Search for Medicinal Seed from Marine Organisms.2009

    • Author(s)
      Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai
    • Organizer
      The 25th Naito Conference on Chemical Biology [II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋由来真菌が産生するsterigmatocystin類のbiofilm形成阻害活性2009

    • Author(s)
      荒井雅吉、石田俊介、坪谷好恵、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋由来真菌が産生するsterigmatocystin類のbiofilm形成阻害活性2009

    • Author(s)
      荒井雅吉、石田俊介、坪谷好恵、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 低酸素環境選択的細胞増殖阻害物質furospinosulin-1および活性アナログ化合物の合成研究2009

    • Author(s)
      住井裕司、古徳直之、藤岡真一、河内崇志、荒井雅吉、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 生薬polygala senega由来サポニンsenegin類の血管新生阻害作用2009

    • Author(s)
      荒井雅吉、林亜紗実、石田俊介、河内崇志、惣坊真理、古徳直之、小林資正
    • Organizer
      第3回食品薬学シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-12
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋生物成分からの新しい抗がん剤シーズ探索2009

    • Author(s)
      荒井雅吉、古徳直之、小林資正
    • Organizer
      近畿大学薬学総合研究所・大学院薬学研究科・文部科学省私立大学学術高度化推進事業、ハイテク・リサーチ・センター整備事業第5回シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-06-27
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する新規アミノリポペプチドtrichoderin類の抗結核活性2009

    • Author(s)
      Patamaporn Pruksakorn、荒井雅吉、古徳直之、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋由来真菌が産生する新規アミノリポペプチドtrichoderin類の抗結核活性2009

    • Author(s)
      Patamaporn Pruksakorn、荒井雅吉、古徳直之、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 生薬Polygala senega由来サポニンsenegin類の血管新生阻害作用2009

    • Author(s)
      荒井雅吉、林亜紗実、石田俊介、河内崇志、惣坊真理、古徳直之、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生するセスキテルペンpyripyropene類のHUVECs選択的増殖抑制効果2009

    • Author(s)
      林亜紗実、荒井雅吉、藤田真由美、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] Hypoxia-selective growth inhibitor, furospinosulin-1, from Indonesian marine sponge.2009

    • Author(s)
      Masayoshi Arai, Takashi Kawachi, Naoyuki Kotoku, Yuji Sumii, Motomasa Kobayashi
    • Organizer
      The 25th Naito Conference on Chemical Biology [II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海綿由来の大環状アルカロイドhaliclonacyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズム解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、藤本貴男、惣坊真理、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋由来真菌が産生する5-methoxysterigmatocystinのbiofilm形成阻害活性2009

    • Author(s)
      石田俊介、荒井雅吉、坪谷好恵、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海綿由来の大環状アルカロイドhaliclonacyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズム解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、藤本貴男、惣坊真理、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] Search for Medicinal Seed from Marine Organisms.2009

    • Author(s)
      Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai
    • Organizer
      The 25th Naito Conference on Chemical Biology[II]
    • Place of Presentation
      北海道
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する新規アミノリポペプチドtrichoderin類の抗結核活性とその作用メカニズム2009

    • Author(s)
      荒井雅吉、Patamaporn Pruksakorn、古徳直之、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] インドネシア産海綿由来furospinosulin-1の低酸素環境選択的細胞毒性2009

    • Author(s)
      荒井雅吉、河内崇志、小林資正
    • Organizer
      第13回日本がん分子標的治療学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] インドネシア産海綿由来furospinosulin-1の低酸素環境特異的がん細胞増殖阻害2009

    • Author(s)
      荒井雅吉、河内崇志、古徳直之、住井裕司、藤岡真一、小林資正
    • Organizer
      第51回天然有機化合物討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋由来真菌が産生する5-methoxysterigmatocystinのbiofilm形成阻害活性2009

    • Author(s)
      石田俊介、荒井雅吉、坪谷好恵、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海洋由来真菌が産生するセスキテルペンpyripyropene類のHUVECs選択的増殖抑制効果2009

    • Author(s)
      林亜紗実、荒井雅吉、藤田真由美、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 海綿由来の大環状アルカロイドhaliclonacyclamine類の潜在性結核菌に対する抗菌活性とその作用メカニズム解析2009

    • Author(s)
      荒井雅吉、劉柳、石田俊介、藤本貴男、惣坊真理、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する新規アミノリポペプチドtrichoderin類の抗結核活性とその作用メカニズム2009

    • Author(s)
      荒井雅吉、Patamaporn Pruksakorn、古徳直之、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21310143
  • [Presentation] 海洋由来真菌が産生するsterigmatocystin類のbiofilm形成阻害活性2009

    • Author(s)
      荒井雅吉、石田俊介、坪谷好惠、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する5-methoxysterigmatocystinのbiofilm形成阻害活性2009

    • Author(s)
      石田俊介、荒井雅吉、坪谷好惠、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21406002
  • [Presentation] 海洋由来真菌が産生する新規アミリポペプチドtrichoderin類の抗結核活性とその作用メカニズム2009

    • Author(s)
      荒井雅吉、Patamaporn Pruksakorn、古徳直之、小林資正
    • Organizer
      日本生薬学会第56回年会
    • Place of Presentation
      京都
    • Year and Date
      2009-10-04
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] インドネシア長野海綿由来furospinosulin-1の低酸素環境選択的細胞毒性2009

    • Author(s)
      荒井雅吉、河内崇志、小林資正
    • Organizer
      第13回日本がん分子標的治療学会
    • Place of Presentation
      徳島
    • Year and Date
      2009-06-25
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] 低酸素環境選択的細胞増殖阻害物質furospinosulin-1および活性アナログ化合物の合成研究2009

    • Author(s)
      住井裕司、古徳直之、藤岡真一、河内崇志、荒井雅吉、小林資正
    • Organizer
      第59回日本薬学会近畿支部総会・大会
    • Place of Presentation
      大阪
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Bioactive metabolites from marine sponges and marine microorganisms2008

    • Author(s)
      小林資正
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      米国(招待講演)
    • Year and Date
      2008-02-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Bioactive metabolites from marine sponges and microorganisms2008

    • Author(s)
      M. Kobayashi
    • Organizer
      Gordon Research Conference-2008 (Marine Natural Products)
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2008-02-24
    • Data Source
      KAKENHI-PROJECT-16073212
  • [Presentation] Bioactive metabolites from marine sponges and marine microorganisms2008

    • Author(s)
      小林資正
    • Organizer
      Gordon Research Conference
    • Place of Presentation
      米国
    • Year and Date
      2008-02-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Bioactive metabolites from marine sponges and microorganisms2008

    • Author(s)
      M. Kobayashi
    • Organizer
      GordonResearch Conference-2008(Marine Natural Products)
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2008-02-24
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] Anti-angiogenic substances from marine sponges2007

    • Author(s)
      M. Kobayashi
    • Organizer
      6^<th> US-Japan Seminar : Frontiers in marine natural products research
    • Place of Presentation
      Park City, Utah, USA
    • Year and Date
      2007-07-01
    • Data Source
      KAKENHI-PROJECT-16073212
  • [Presentation] Anti-angiogenic substances from marine sponges2007

    • Author(s)
      M. Kobayashi
    • Organizer
      6th US-Japan Seminar: Frontiers in marine natural products research
    • Place of Presentation
      Park City, Utah, USA
    • Year and Date
      2007-07-01
    • Data Source
      KAKENHI-PROJECT-18201042
  • [Presentation] プローブ分子を用いたcortistatin A の標的分子の解析研究

    • Author(s)
      伊藤 葵,古徳直之,住井裕司,角居雄太,小林資正
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学等(熊本市)
    • Year and Date
      2014-03-27 – 2014-03-30
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質furospinosulin-1のin vivo評価

    • Author(s)
      荒井雅吉,河内崇志,古徳直之,遠藤洋子,井上正宏,小林資正
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      北海道医療大学(北海道)
    • Year and Date
      2013-09-07 – 2013-09-08
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋天然物furospinosulin-1を利用する新規がん細胞低酸素適応因子の創出

    • Author(s)
      河内崇志、荒井雅吉、古徳直之、小林資正
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ等(仙台市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 海洋由来放線菌が産生するnybomycinの潜在性結核菌に対する抗菌活性とその作用メカニズム

    • Author(s)
      荒井雅吉、神谷謙太朗、住井裕司、 申 多英、 Patamaporn Pruksakorn、韓 智秀、古徳直之、小林資正
    • Organizer
      日本生薬学会第61回年会
    • Place of Presentation
      福岡大学(福岡市)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] ゲノムDNAライブラリーを利用する抗菌物質の標的分子解析 - 潜在性結核菌に有効な海綿由来テトラミン酸melophlin類の標的分子解析 -

    • Author(s)
      荒井 雅吉、 古徳 直之、小林 資正
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」 第6回公開シンポジウム
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2014-05-28 – 2014-05-29
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 海綿由来の新しい医薬シーズの探索

    • Author(s)
      小林 資正
    • Organizer
      中西シンポジウム2012
    • Place of Presentation
      慶応義塾大学 日吉キャンパス
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 海洋天然物furospinosulin-1を利用する新規がん細胞低酸素適応因子の創出

    • Author(s)
      河内崇志、荒井雅吉、古徳直之、小林資正
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ等(仙台市)
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] Target identification of anti-tumor depsi-peptide, arenastatin A, by the method of phage display

    • Author(s)
      Masayoshi Arai, Naoyuki Kotoku, Motomasa Kobayashi
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」 第3回国際シンポジウム(第7回公開シンポジウム)
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府)
    • Year and Date
      2014-10-28 – 2014-10-29
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 医薬シーズとしての活性天然物の探索とその標的分子の解析

    • Author(s)
      小林 資正
    • Organizer
      新学術領域「天然物ケミカルバイオロジー」 第一回公開シンポジウム
    • Place of Presentation
      大阪市立大学
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] 新しい医薬シーズの探索と標的分子探索

    • Author(s)
      小林資正
    • Organizer
      日本生薬学会第60回年会
    • Place of Presentation
      北海道医療大学(北海道)
    • Year and Date
      2013-09-07 – 2013-09-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] 海洋由来放線菌が産生するnybomycinの潜在性結核菌に対する抗菌活性とその作用メカニズム

    • Author(s)
      神谷謙太朗、荒井雅吉、住井裕司、申 多英、Patamaporn Pruksakorn、韓 智秀、古徳直之、小林資正
    • Organizer
      日本生薬学会第61回年会
    • Place of Presentation
      福岡大学(福岡市)
    • Year and Date
      2014-09-13 – 2014-09-14
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] Phage Display法を利用した抗腫瘍性物質arenastatin Aの標的分子解析

    • Author(s)
      河内崇志、荒井雅吉、馬田哲也、古徳直之、高市伸宏、小林資正
    • Organizer
      第20回天然薬物の開発と応用シンポジウム
    • Place of Presentation
      東京大学(東京都)
    • Year and Date
      2014-11-05 – 2014-11-06
    • Data Source
      KAKENHI-PLANNED-23102005
  • [Presentation] グルコース飢餓環境選択的がん細胞増殖阻害作用を有する新規ポリケチド類の化学構造と生物活性

    • Author(s)
      古徳直之、戸田和成、荒井雅吉、石田良典、松本紘和、村岡 修、小林資正
    • Organizer
      第56回天然有機化合物討論会
    • Place of Presentation
      高知県立県民文化ホール(高知県)
    • Year and Date
      2014-10-15 – 2014-10-17
    • Data Source
      KAKENHI-PROJECT-26305002
  • [Presentation] 低酸素環境選択的がん細胞増殖阻害物質furospinosulin-1の標的分子の解明

    • Author(s)
      荒井雅吉,河内崇志,中田千晶,古徳直之,小林資正
    • Organizer
      第55回天然有機化合物討論会
    • Place of Presentation
      同志社大学(京都市)
    • Year and Date
      2013-09-18 – 2013-09-19
    • Data Source
      KAKENHI-PROJECT-22241053
  • [Presentation] Medicinal Seeds for Cancer Chemotherapy from Marine Organisms

    • Author(s)
      Motomasa Kobayashi
    • Organizer
      7th U.S.-Japan Seminar on Marine Natural Products
    • Place of Presentation
      沖縄コンベンションセンター
    • Invited
    • Data Source
      KAKENHI-PLANNED-23102005
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  • 2.  ARAI Masayoshi (80311231)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 191 results
  • 3.  KITAGAWA Isao (20028830)
    # of Collaborated Projects: 9 results
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  • 4.  KOTOKU Naoyuki (20362618)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 81 results
  • 5.  SHIBUYA Hirotaka (50116042)
    # of Collaborated Projects: 6 results
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  • 6.  HIGA Tatsuo (10101461)
    # of Collaborated Projects: 6 results
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  • 7.  MURAKAMI Nobutoshi (00210013)
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  • 8.  TANAKA Junichi (20163529)
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  • 9.  OHASHI Kazuyoshi (90213826)
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  • 10.  伏谷 伸宏 (70012010)
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    # of Collaborated Projects: 3 results
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    # of Collaborated Projects: 3 results
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  • 14.  FUJOKA Haruto (20167753)
    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  HORI Kazuyuki (50181516)
    # of Collaborated Projects: 1 results
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  • 23.  YOSHIKAWA Masayuki (90116129)
    # of Collaborated Projects: 1 results
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  • 25.  福山 透 (10272486)
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  • 50.  ロエマンチョ ハリニムル
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  • 51.  リスワン スダルソノ
    # of Collaborated Projects: 1 results
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  • 52.  パルトムアン シマンジュ
    # of Collaborated Projects: 1 results
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  • 53.  ハリニ・ムルニ ロエマン
    # of Collaborated Projects: 1 results
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  • 54.  スダルソノ リスワン
    # of Collaborated Projects: 1 results
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  • 55.  ROEMANTYO Harini M.
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  • 56.  PARTOMUAN Si
    # of Collaborated Projects: 1 results
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  • 57.  TUKIRIN Part
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  • 58.  HARINIーMURUN ロエマンチョ
    # of Collaborated Projects: 1 results
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  • 59.  ジョコー ハディクナルソ
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  • 60.  ラクマニアール サタリ
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  • 62.  KUNARSO Djoki Hadi
    # of Collaborated Projects: 1 results
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  • 63.  ハディクナルソ ジョコー
    # of Collaborated Projects: 1 results
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  • 64.  サタリ ラクマニアール
    # of Collaborated Projects: 1 results
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  • 65.  住井 裕司
    # of Collaborated Projects: 0 results
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