HIRAKI Yuji 開祐司

… Alternative Names

開裕司ヒラキユウジ

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Researcher Number	40144498
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2017: 京都大学ウイルス, 再生医科学研究所, 教授 2016 – 2017: 京都大学, ウイルス・再生医科学研究所, 教授 2013 – 2015: 京都大学, 再生医科学研究所, 教授 2011: 京都大学, 再生医科研究所, 教授 1998 – 2011: Institute for Frontier Medical Sciences, Professor, 再生医科学研究所, 教授 … More 2004: 京都大学, 再生医科学研究科, 教授 1994 – 1997: Osaka Univ.Fac.of Dentistry, Assoc.Prof., 歯学部, 助教授 1991 – 1993: 大阪大学, 歯学部, 講師 1989 – 1991: 大阪大学, 歯学部, 助手 1986: Faculty of Dentistry , Research assistant, Osaka University, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / 物質生物化学 / Living organism molecular science / Biological Sciences / Biomolecular chemistry / 血管生物学 Except Principal Investigator 内分泌・代謝学 / Orthopaedic surgery / 代謝生物化学 / Science and Engineering … More / Functional biochemistry / 小児・社会系歯学 / Chemistry related to living body / Laboratory animal science / Nanomaterials/Nanobioscience / 病態科学系歯学(含放射線系歯学) / Experimental pathology / 矯正・小児・社会系歯学 / Orthopaedic surgery Less
Keywords	Principal Investigator Chondromodulin-I / 軟骨細胞 / 細胞分化 / 血管新生抑制因子 / コンドロモジュリン-I / 細胞外基質 / chondromodulin-I / 血管内皮細胞 / 腫瘍血管新生 / 軟骨肉腫 … More / 軟骨 / Cell Differentiation / Chondromodulin-II / Chondrocytes / Angiogenesis / 血管新生 / Chondrocyte / Cellular Differentiation / Extracellular Matrix / Bone Formation / Chondrosurfactant / 骨形成 / fibroblast growth factor / 細胞外マトリックス / 活性発現の分子機構 / 発生・分化 / 結合組織 / 血管侵入抵抗性 / tenomodulin / コンドロモジュリン-1 / エンドプロテアーゼ / コンドロモジュリン / 軟骨マトリックス / Chondromoduin-I / 切断酵素 / アンカー分子 / Morphogenesis / in situ Hybridization / Vascular Endothelial Cell / 形態形成 / in situ hybridization / Osteoclast / Cartilage Matrix / Growth Differentiation Factor / 軟骨内骨化 / 細胞分化因子 / 破軟骨細胞 / 石灰化 / 破骨細胞 / 軟骨基質 / 増殖分化因子 / Growth Inhibitor / 増殖阻害因子 / Fibroblast Growth Factor / Growth Factor / ChondromodulinーI / 線維芽細胞成長因子 / 成長因子 / endochondral bone formation / extracellular matrix / cell growth / cell differentiation / chondrocyte / Cartilage-derived factor / プロテオグリカン合成 / アミノ酸配列 / 精製 / cDNAクロ-ニング / 内軟骨性骨形成 / 細胞増殖 / chondromodulinーI / 軟骨由来成長因子 / 蛋白質分解 / プロテオリシス / 軟骨細胞外マトリックス / 抗腫瘍血管新生因子 / コンドロモジュリン.I / 癌 / 蛋白質 / 血管進入抵抗性 / 組織・細胞 / 生体分子 / VEGF / 軟骨分化 / 転写制御 / chondromodulin-1 / 唾液腺多形腺種 / ゼブラフィッシュ / 網膜内皮細胞 / 眼組織 / 強靭結合組織 / ノックアウトマウス / アデノウイルスベクター / 脱落膜 / 腱・靭帯 / TeM / ChM-I / 血管侵入障 / 機能性細胞外マトリックス / 抗リウマチ / Multiple Endocrine Neoplasia type 2 / Tenomodulin / 組織間相互作用 / 血管侵入障壁 / 遺伝子構造 / 胚発生 / 結腸ガン / 関節軟骨 / アデノカルシノーマ / 抗腫瘍因子 / 遠隔転移 / 腫瘍造成 … More Except Principal Investigator 軟骨細胞 / Chondrocyte / Chondromodulin-I / フェムト秒レーザー / II型コラーゲン / 受容体 / 修復過程 / 腱骨結合部 / scleraxis / progenitor / tendon-bone healing / enthesis / 腱板 / Sox9 / Scleraxis / Differentiation / Growth / Serum-free medium / プロテオグリカン / 分化 / 成長 / 無血清培地 / EGFP Modification / Actin Stress Fiber / Fluorescence Imaging / Dextran / Mousr NIH3T3 Cell / Femtosecond Laser / Single Bio Cell / Light Scattering Microspectroscopy / アクチィンフィラメント / 形態変化 / 衝撃波 / 緑色蛍光蛋白質 / アクチンフィラメント / 単一細胞 / EGFP修飾 / アクチンストレスファイバー / 蛍光イメージング / デキストラン / マウスNIH3T3細胞 / 単一生細胞 / 顕微光散乱分光 / Cell Differentiation / Processig / Cartilage Matrix / Growth Factor / 細胞分化 / プロセシング / 軟骨基質 / 増殖因子 / Osteopontin / Osteonectin / Alkaline Phosphatase / Type X Collagen / Type II Collagen / Type I Collagen / Mandibular Chondrocytes / タイプXコラーゲン / タイプIIコラーゲン / タイプIコラーゲン / オステオポンチン / オステオネクチン / アルカリフォスファターゼ / X型コラーゲン / I型コラーゲン / 下顎頭軟骨細胞 / 部位特異的修飾 / チオエステル / タンパク質 / ペプチド / 生体分子 / ゲノム / 発現制御 / 発生・分化 / 軟骨形成 / 比較ゲノム / 微粒子導入 / 金ナノ粒子 / キャビテーションバブル / 細胞外マトリックス / マイクロマニピュレーション / 単一細胞操作 / 動物細胞 / レーザー誘起衝撃波 / RT-PCR / 初代細胞培養 / in-situハイブリダイゼーション / CT造影画像診断 / 唾液腺筋上皮腫 / 唾液腺多形性腺腫 / 血管新生抑制因子 / コンドロモデュリン-I / 2国間共同研究 / 2国間協同研究 / ヒトゲノム / がん転移 / DNA修復 / がん細胞 / シグナル伝達 / がん抑制遺伝子 / がん遺伝子 / cartilage / cloning / Chondromodulin / ヒトChM-I遺伝子 / ヒトChM-IcDNA / クローニング / ヒト高分化型軟骨肉腫 / アグリカン / 発現ベクター / アンチセンス / 軟骨の分化 / 副甲状腺ホルモン関連ペプチド / 骨誘導蛋白質 / 血管新生 / 線維芽細胞成長因子 / コンドロモジュリン / 蛋白精製 / 遺伝子クローニング / ヒト腎細胞癌 / 破骨細胞 / 骨吸収 / ^<111>In / 発現クロ-ニング / 副甲状腺ホルモン Less

Elucidating the involvement of Scleraxis-positive progenitors during rotator cuff tendon-bone healing after acute injury in mice
- Principal Investigator
  
  TOKUNAGA Takuya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kumamoto University
Exploring the anchoring molecules and cleaving enzymes of Chondromodulin-I, a cartilage-derived angiogenesis inhibitorPrincipal Investigator
- Principal Investigator
  
  Hiraki Yuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Kyoto University
Analysis of the molecular mechanism of vertebral column formation by a cross-species genome engineering approach between mice and zebrafish
- Principal Investigator
  
  KOKUBU Chikara
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
Development of a method for protein labeling by the use of intramolecular thioester-forming unit
- Principal Investigator
  
  KAWAKAMI Toru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Osaka University
The structural determination and anti-angiogenic activity of a Chondromodulin-I subtype that lacks the N-terminal domain.Principal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
The structural domains of Chondromodulin-I, an angiogenesis inhibitor, and their contribution to its bioactivityPrincipal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
Molecular basis of anti-angiogenic barriers in mesenchymal tissuesPrincipal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
フェムト秒レーザー誘起衝撃波による単一細胞の操作とナノ粒子導入法の開発
- Principal Investigator
  
  MASUHARA Hiroshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Osaka University
Creation of Reaction Fields in Single Bio Cells and Measurement of Their Reactions
- Principal Investigator
  
  MASUHARA Hiroshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Osaka University
間葉系組織構築を制御する増殖分化因子群Principal Investigator
- Principal Investigator
  
  開祐司
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ヨーロッパなどががん研究先進国との研究交流
- Principal Investigator
  
  黒木登志夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Experimental pathology
- Research Institution
  Showa University
血管新生阻害因子コンドロモジュリン-Iの発現動態と抗腫瘍活性Principal Investigator
- Principal Investigator
  
  開祐司
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
唾液腺多形性腺腫の血管に乏しい間質の分子病理学的特性とCT造影性
- Principal Investigator
  
  朔敬
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Niigata University
軟骨の悪性腫瘍化と血管新生阻害因子コンドロモジュリン-1の役割Principal Investigator
- Principal Investigator
  
  開祐司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto University
腫瘍造成に対する軟骨由来血管新生阻害因子コンドロモジュリン-Iの作用Principal Investigator
- Principal Investigator
  
  開祐司
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Cloning of Mouse Chondromodulin-I cDNA and Localization of the Gene TranscriptsPrincipal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  KYOTO UNIVERSITY
  Osaka University
ヒトコンドロモジュリン-I遺伝子の構造決定
- Principal Investigator
  
  飯田寛和
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kyoto University
軟骨由来増殖制御因子Chondromodulin-IIのクローニング
- Principal Investigator
  
  INOUE Hiroyuki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Osaka University
軟骨由来増殖制御因子コンドロモジュリン-Iの血管新生阻害活性と骨形成の制御
- Principal Investigator
  
  SUZUKI Fujio
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
軟骨の分化における副甲状腺ホルモン関連ペプチドの役割
- Principal Investigator
  
  池田恭治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  The University of Tokyo
Purification of Osteoclast Differentiation Factor produced by Epiphyseal CartilagePrincipal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Biosynthesis and Complex Formation of Cartilage Specific Functional Matrix/Chondromodulin-I
- Principal Investigator
  
  SUZUKI Fujio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Inhibitory action mechanism of cartilage-specific functional martix/chondromodulin-I on growth of vascular endothelial cells.Principal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Osaka University
ヒト腎細胞癌由来骨吸収促進因子の精製,同定及びその遺伝子クローニング
- Principal Investigator
  
  滋野長平
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyoto University
Study on the mechanism of terminal differentiation and calcification of cultured mandibular chondrocytes
- Principal Investigator
  
  NAKAGAWA Koichi, 井上博之
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  小児・社会系歯学
- Research Institution
  Osaka University
副甲状腺ホルモン受容体の同定に関する研究
- Principal Investigator
  
  滋野長平
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Kyoto University
Molecular cloning of a cartilage-derived growth modulating factor, chondromodulin-I(ChM-I) and functional expression of ChM-I cDNAPrincipal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Osaka University
Isolation and Identification of Cartilage-derived Factor (CDF) and its Precursor.Principal Investigator
- Principal Investigator
  
  HIRAKI Yuji
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Osaka University
A new serum-free system for chondrocytes: analysis of mechanisms involved in the control of chondrocyte growth and differentiation
- Principal Investigator
  
  KATO Yukio
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  14401 Osaka University

All 2018 2017 2013 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] Nano Biophotonics : Science and Technology (第15,16,22,24章)2007
- Author(s)
  Hiroshi Masuhara, Tsuyoshi Asahi, Yuuji Hiraki, et al.
- Total Pages
  428
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-16072211
[Book] 生命科学(柳田充弘, 佐藤文彦, 石川冬木編集), pp. 165-1732004
- Author(s)
  開祐司(分担執筆)
- Total Pages
  244
- Publisher
  東京化学同人
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] エンテーシスの形成と再生への展望2018
- Author(s)
  徳永琢也, 有村仁志, 水田博志, 開祐司, 宿南知佐
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 28 Pages: 335-343
- Data Source
  KAKENHI-PROJECT-16K20062
[Journal Article] Pax1 acts as a negative regulator of chondrocyte maturation.2013
- Author(s)
  Takimoto A, Mohri H, Kokubu C, Hiraki Y, Shukunami C.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 319 Issue: 20 Pages: 3128-3139
- DOI
  10.1016/j.yexcr.2013.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300154
[Journal Article] A functional role of the glycosylated N-terminal domain of chondromodulin-I.2010
- Author(s)
  J. Kondo, H. Shibata, S. Miura, A. Yamakawa, K. Sato, Y. Higuchi, C. Shukunami, Y. Hiraki
- Journal Title
  
  J. Bone Miner. Metab. (印刷中)
- NAID
  10029023545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Yasui Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells2010
- Author(s)
  K. Yukata, Y. Matsui, C. Shukunami, A. Takimoto, N. Hirohashi, O. Ohtani, T. Kimura, Y. Hiraki, N
- Journal Title
  
  Tissue & Cell
  
  Volume: 42 Issue: 2 Pages: 116-120
- DOI
  10.1016/j.tice.2010.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510224, KAKENHI-PROJECT-22390289
[Journal Article] Impairment of VEGF-A-stimulated lamellipodial extensions and motility of vascular endothelial cells by Chondromodulin-I, a cartilage-derived angiogenesis inhibitor.2010
- Author(s)
  S. Miura, K. Mitsui, T. Heishi, C. Shukunami, K. Sekiguchi, J. Kondo, Y. Sato, Y. Hiraki
- Journal Title
  
  Exp. Cell Res. 316
  
  Pages: 775-788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] The roles of chondromodulin-I and NQO1 in the inhibition of tube formation induced by the benzene metabolite hydroquinone in human bone marrow endothelial cells.2009
- Author(s)
  H. Zhou, J.K. Kepa, D. Siegel, S. Miura, Y. Hiraki, D. Ross
- Journal Title
  
  Mol. Pharmacol. 76
  
  Pages: 579-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Analyses of early events during chondrogenic repair in rat full-thickness articular cartilage defects.2009
- Author(s)
  Y. Anraku, H. Mizuta, A. Sei, S. Kudo, E. Nakamura, K. Senba, Y. Hiraki
- Journal Title
  
  J. Bone Min. Metab. 27
  
  Pages: 272-286
- NAID
  10025337240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Differential actions of VEGF-A isoforms on perichondrial angiogenesis during endochondral bone formation.2009
- Author(s)
  A. Takimoto, Y. Nishizaki, Y. Hiraki, C. Shukunami
- Journal Title
  
  Dev. Biol. 322
  
  Pages: 196-211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Local tenomodulin absence, angiogenesis, and MMP activation are associated with the rupture of the chordae tendineae cordis.2008
- Author(s)
  N. Kimura, C. Shukunami, D. Hakuno, M. Yoshioka, S. Miura, D. Docheva, T. Kimura, Y. Okada, G. Matsumura, T. Shin'oka, R. Yozu, J. Kobayashi, H. Ishibashi-Ueda, Y. Hiraki, K. Fukuda
- Journal Title
  
  Circulation 118
  
  Pages: 1737-1747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Altered fracture callus formation in chondromodulin-I deficient mice.2008
- Author(s)
  K. Yukata, Y. Matsui, C. Shukunami, A. Takimoto, T. Goto, Y. Nishizaki, Y. Nakamichi, T. Kubo, T. Sano, S. Kato, Y. Hiraki, N. Yasui
- Journal Title
  
  Bone 43
  
  Pages: 1047-1056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Expression of marker genes during otolith development in medaka.2008
- Author(s)
  Y. Nemoto, K. Inohaya, Y. Hiraki, A. Kudo
- Journal Title
  
  Gene Expr Patterns 8
  
  Pages: 92-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Chondromodulin-I and Tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development2008
- Author(s)
  C. Shukunami, A. Takimoto, S. Miura, Y. Hiraki
- Journal Title
  
  Cell Tissue Res. 332
  
  Pages: 111-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510217
[Journal Article] The chondrogenic repair response of undifferentiated mesenchymal cells in rat full-thickness articular cartilage defects.2008
- Author(s)
  Y. Anraku, H. Mizuta, S. Kudo, E. Nakamura, K. Takagi, Y. Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 16
  
  Pages: 961-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Cartilaginous features in matrix-producing carcinoma of the breast: four cases report with histochemical and immunohistochemical analysis of matrix molecules.2008
- Author(s)
  K. Kusafuka, K. Muramatsu, M. Kasami, K. Kuriki, K. Hirobe, I. Hayashi, H. Watanabe, Y. Hiraki, C. Shukunami, T. Mochizuki, T. Kameya
- Journal Title
  
  Modern Pathology 21
  
  Pages: 1282-1292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] The chondrogenic repair response of undifferentiated mesenchymal cells in rat full-thickness articular cartilage defects2008
- Author(s)
  Y. Anraku, H. Mizuta, S. Kudo, E. Nakamura, K. Takagi, Y. Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 16
  
  Pages: 961-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510217
[Journal Article] Altered fracture callus formation in chondromodulin-I deficient mice2008
- Author(s)
  K. Yukata, Y. Matsui, C. Shukunami, A. Takimoto, T. Goto, Y. Nishizaki, Y. Nakamichi, T. Kubo, T. Sano, S. Kato, Y. Hiraki, N. Yasui
- Journal Title
  
  Bone 43
  
  Pages: 1047-1056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510217
[Journal Article] Chondromodulin-I and Tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development.2008
- Author(s)
  C. Shukunami, A. Takimoto, S. Miura, Y. Nishizaki, Y. Hiraki
- Journal Title
  
  Cell Tissue Res. 332
  
  Pages: 111-122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Chondromodulin-I and Tenomodulin: the Negative Control of Angiogenesis in Connective Tissue.2007
- Author(s)
  C. Shukunami, Y. Hiraki
- Journal Title
  
  Curr. Pharm. Design 13
  
  Pages: 2101-2112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Dual effects of the membrane-anchored MMP regulator RECK on chondrogenic differentiation of ATDC5 cells.2007
- Author(s)
  S. Kondo, C. Shukunami, Y. Morioka, N. Matsumoto, R. Takahashi, J. Oh, T. Atsumi, A. Umezawa, A. Kudo, H. Kitayama, Y. Hiraki, M. Noda
- Journal Title
  
  J. Cell Sci. 120
  
  Pages: 849-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Realignment Process of Actin Stress Fibers in Single Living Cells Studied by Focused Femtosecond Laser Irradiation2007
- Author(s)
  Ryohei Yasukuni, Jean-Alexis Spitz, Rachel Meallet-Renault, Takayuki Negishi, Takuji Tada, Yoichiro Hosokawa, Tsuyoshi Asahi, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Journal Title
  
  Appl. Surface Sci. (in press)
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Dual Effects of the Membrane-anchored MMP Regulator RECK on Chondrogenic Differentiation of ATDC5 Cell2007
- Author(s)
  Shunya Kondo, Chisa Shukunami, Yoko Morioka, Naoya Matsumoto, Rei Takahashi, Junseo Oh, Tadao Atsumi, Akihiro Umezawa, Akira Kudo, Hitoshi Kitayama, Yuji Hiraki, Makoto Noda
- Journal Title
  
  J. Cell Sci. (in press)
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] In situ Micro-patterning of Proteinous Occlusion Bodies in Water by Femtosecond Laser-Induced Mechanical Fore2007
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Chisa Shukunami, Yuji Hiraki, Eiji Kotani, Hajime Mori, Hiroshi Masuhara
- Journal Title
  
  Biomedical Microdevices (in press)
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Dual Effects of the Membrane-anchored MMP Regulator RECK on Chondrogenic Differentiation of ATDC5 Cells2007
- Author(s)
  Shunya Kondo, Chisa Shukunami, Yoko Morioka, Naoya Matsumoto, Rei Takahashi, Junseo Oh, Tadao Atsumi, Akihiro Umezawa, Akira Kudo, Hitoshi Kitayama, Yuji Hiraki, Makoto Noda
- Journal Title
  
  J. Cell Sci. 120
  
  Pages: 849-857
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] the Negative Control of Angiogenesis in Connective Tissue. Curr. Pharm2007
- Author(s)
  C. Shukunami, Y. Hiraki Chondromodulin-I and Tenomodulin
- Journal Title
  
  Design 13
  
  Pages: 2101-2112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510217
[Journal Article] Realignment Process of Actin Stress Fibers in Single Living Cells Studied by Focused Femtosecond Laser Irradiation2007
- Author(s)
  Ryohei Yasukuni, Jean-Alexis Spitz, Rachel Meallet-Renault, Takayuki Negishi, Takuji Tada, Yoichiroh Hosokawa, Tsuyoshi Asahi, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Journal Title
  
  Appl. Surf. Sci. (in press)
- Data Source
  KAKENHI-PROJECT-16651067
[Journal Article] Regeneration of Full-thickness Defects of Articular Cartilage in Rabbit Using FGF-2 and a Fibrin Sealant.2007
- Author(s)
  I. Ishii, H. Mizuta, A. Sei, J. Hirose, S. Kudo, Y. Hiraki
- Journal Title
  
  J. Bone Joint Surg, Br. 89-B
  
  Pages: 693-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Nondestructive Micro-Patterning of Proteinous Occlusion Bodies in Water by Femtosecond Laser-Induced Mechanical Force2007
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Chisa Shukunami, Yuji Hiraki, Eiji Kotani, Hajime Mori, Hiroshi Masuhara
- Journal Title
  
  Biomedical Microdev (in press)
- Data Source
  KAKENHI-PROJECT-16651067
[Journal Article] Chondromodulin-I and Tenomodulin: the Negative Control of Angiogenesis in Connective Tissue.2007
- Author(s)
  Shukunami C, Hiraki Y
- Journal Title
  
  Curr Pharm Design 13
  
  Pages: 2101-2112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19510217
[Journal Article] The immobilization of bioactive FGF-2 into cubic proteinous micro-crystals (Bombyx mori cypovirus polyhedra) that are insoluble in a physiological cellular environment.2007
- Author(s)
  H. Mori, C. Shukunami, A. Furuyama, H. Notsu, Y. Nishizaki, Y. Hiraki
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 17289-17296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Expression of the PTH/PTHrP Receptor in Chondrogenic Cells During the Repair of Full-Thickness Defects of Articular Cartilage2006
- Author(s)
  Hiroshi Mizuta, Satoshi Kudo, Eiichi Nakamura, Katsumasa Takagi, Yuji Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 14(9)
  
  Pages: 944-952
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Scleraxis Positively Regulates the Lineage-specific Expression of Tenomodulin, a Marker of Tenocytes2006
- Author(s)
  Chisa Shukunami, Aki Takimoto, Miwa Oro, Yuji Hiraki
- Journal Title
  
  Dev. Biol. 298(1)
  
  Pages: 234-247
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Scleraxis Positively Regulates the Lineage-specific Expression of Tenomodulin, a Marker of Tenocytes2006
- Author(s)
  Chisa Shukunami, Aki Takimoto, Miwa Oro, Yuji Hiraki
- Journal Title
  
  Dev. Biol. 298 (1)
  
  Pages: 234-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Scleraxis positively regulates the lineage-specific expression of tenomodulin, a marker of tenocytes.2006
- Author(s)
  C. Shukunami, A. Takimoto, M. Oro, Y. Hiraki
- Journal Title
  
  Dev. Biol. 298
  
  Pages: 234-247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Expression of the PTH/PTHrP Receptor in Chondrogenic Cells During the Repair of Full-Thickness Defects of Articular Cartilage2006
- Author(s)
  Hiroshi Mizuta, Satoshi Kudo, Eiichi Nakamura, Katsumasa Takagi, Yuji Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 14 (9)
  
  Pages: 944-952
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Non-destructive Micro-patterning of Protein Crystals by Focused Femtosecond Laser2006
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Yuji Hiraki, Hajime Mori, Hirosi Masuhara
- Journal Title
  
  Proc. SPIE 6108
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis.2006
- Author(s)
  M. Yoshioka, S. Yuasa, K. Matsumura, T. Shiomi, C. Shukunami, Y. Okada, M. Mukai, H. Shin, R. Yozu, M. Sata, S. Ogawa, Y. Hiraki, K. Fukuda
- Journal Title
  
  Nature Medicine 12
  
  Pages: 1151-1159
- NAID
  10017243402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Non-destructive micro-patterning of protein crystals by focused femtosecond laser2006
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Yuji Hiraki, Hajime Mori, Hiroshi Masuhara
- Journal Title
  
  SPIE Proceeding (in press)
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Chondromodulin-I Maintains Cardiac Valvular Function by Preventing Angiogenesis2006
- Author(s)
  Masatoyo Yoshioka, Shinsuke Yuasa, Keisuke Matsumura, Takayuki Shiomi, Chisa Shukunami, Yasunori Okada, Makio Mukai, Hankei Shin, Ryohei Yozu, Masataka Sata, Satoshi Ogawa, Yuji Hiraki, Keiichi Fukuda
- Journal Title
  
  Nature Medicine 12(10)
  
  Pages: 1151-1159
- NAID
  10017243402
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Expression of the PTH/PTHrP Receptor in Chondrogenic Cells During the Repair of Full-Thickness Defects of Articular Cartilage.2006
- Author(s)
  H. Mizuta, S. Kudo, E. Nakamura, K. Takagi, Y. Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 14
  
  Pages: 944-952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Scleraxis Positively Regulates the Lineage-specific Expression of Tenomodulin, a Marker of Tenocytes2006
- Author(s)
  Chisa Shukunami, Aki Takimoto, Miwa Oro, Yuji Hiraki
- Journal Title
  
  Dev. Biol. Vol. 298, No. 1
  
  Pages: 234-247
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Chondromodulin-I Maintains Cardiac Valvular Function by Preventing Angiogenesis2006
- Author(s)
  Masatoyo Yoshioka, Shinsuke Yuasa, Keisuke Matsumura, Takayuki Shiomi, Chisa Shukunami, Yasunori Okada, Makio Mukai, Hankei Shin, Ryohei Yozu, Masataka Sata, Satoshi Ogawa, Yuji Hiraki, Keiichi Fukuda
- Journal Title
  
  Nature Medicine Vol. 12 No. 10
  
  Pages: 1151-1159
- NAID
  10017243402
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Chondromodulin-I Maintains Cardiac Valvular Function by Preventing Angiogenesis2006
- Author(s)
  Masatoyo Yoshioka, Shinsuke Yuasa, Keisuke Matsumura, Takayuki Shiomi, Chisa Shukunami, Yasunori Okada, Makio Mukai, Hankei Shin, Ryohei Yozu, Masataka Sata, Satoshi Ogawa, Yuji Hiraki, Keiichi Fukuda
- Journal Title
  
  Nature Medicine 12 (10)
  
  Pages: 1151-1159
- NAID
  10017243402
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Expression of the PTH/PTHrP Receptor in Chondrogenic Cells During the Repair of Full-Thickness Defects of Articular Cartilage2006
- Author(s)
  Hiroshi Mizuta, Satoshi Kudo, Eiichi Nakamura, Katsumasa Takagi, Yuji Hiraki
- Journal Title
  
  Osteoarthritis Cartilage Vol. 14, No. 9
  
  Pages: 944-952
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Chondromodulin-I and tenomodulin : a new class of tissue-specific angiogenesis inhibitors found in hypovascular connective tissues2005
- Author(s)
  Chisa Shukunami, Yusuke Oshima, Yuji Hiraki
- Journal Title
  
  Biochem.Biophys.Res.Commun. 333(2)
  
  Pages: 299-307
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Angiogenesis Inhibitors Localized in Hypovascular Mesenchymal Tissues : Chondromodulin-I and Tenomodulin.2005
- Author(s)
  Y.Hiraki
- Journal Title
  
  Connect.Tissue Res. 46
  
  Pages: 3-11
- NAID
  10019042443
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Expression and localization of cartilage-specific matrix protein chondromodulin-I mRNA in salivary pleomorphic adenomas.2005
- Author(s)
  K. Kusafuka, K. Nakano, Y. Hiraki, C. Shukunami, H. Nagatsuka, N. Nagai, T. Takemura, Y. Sakaguchi, K. Okazaki, M. Kusafuka, H. Hisha, S. Ikehara
- Journal Title
  
  Virchows Arch. 446
  
  Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Angiogenesis Inhibitors Localized in Hypovascular Mesenchymal Tissues: Chondromodulin-I and Tenomodulin.2005
- Author(s)
  Y. Hiraki, C. Shukunami
- Journal Title
  
  Connect. Tissue Res. 46
  
  Pages: 3-11
- NAID
  10019042443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Chondromodulin-I and tenomodulin: a new class of tissue-specific angiogenesis inhibitors found in hypovascular connective tissues.2005
- Author(s)
  C. Shukunami, Y. Oshima, Y. Hiraki
- Journal Title
  
  Biochem. Biophys. Res. Commun. 333
  
  Pages: 299-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Angiogenesis Inhibitors Localized in Hypovascular Mesenchymal Tissues : Chondromodulin-I and Tenomodulin2005
- Author(s)
  Yuji Hiraki, Chisa Shukunami
- Journal Title
  
  Connect.Tissue Res. 46(1)
  
  Pages: 3-11
- NAID
  10019042443
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Nondestructive isolation of single cultured cells by femtosecond laser-induced shockwave2004
- Author(s)
  Y. Hosokawa, J. Takabayashi, S. Miura, C. Shukunami, Y. Hiraki, H. Masuhara
- Journal Title
  
  Appl. Phys. A 79
  
  Pages: 795-798
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Molecular Basis for the Aggressive Tumor Phenotype and Skeletal Abnormalities in Multiple Endocrine Neoplasia type 2B Syndrome2004
- Author(s)
  S. Jain, M. A. Watson, M. K. DeBenedetti, Y. Hiraki, J. F. Moley, J. Milbrandt
- Journal Title
  
  Caner Res. 64
  
  Pages: 3907-3913
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Molecular Basis for the Aggressive Tumor Phenotype and Skeletal Abnormalities in Multiple Endocrine Neoplasia type 2B Syndrome2004
- Author(s)
  S. Jain, M. A. Watson, M. K. DeBenedetti, Y. Hiraki, J.F. Moley, J. Milbrandt
- Journal Title
  
  Caner Res. 64
  
  Pages: 3907-3913
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I2004
- Author(s)
  Y. Oshima, K. Sato, F. Tashiro, J. Miyazaki, K. Nishida, Y. Hiraki, Y. Tano, C. Shukunami
- Journal Title
  
  J. Cell Sci. 117
  
  Pages: 2731-2744
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] 集光フェムト秒レーザー衝撃波を用いた単一細胞加工2004
- Author(s)
  細川陽一郎, 高林淳一, 宿南知佐, 開祐司, 増原宏
- Journal Title
  
  レーザー加工学会 11
  
  Pages: 190-192
- Data Source
  KAKENHI-PROJECT-16651067
[Journal Article] One day exposure to FGF-2 was sufficient for the regenerative repair of full-thickness defects of articular cartilage in rabbits2004
- Author(s)
  H. Chuma, H. Mizuta, S. Kudo, K. Takagi, Y. Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 12
  
  Pages: 834-842
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I2004
- Author(s)
  Y. Oshima, K. Sato, F. Tashiro, J. Miyazaki, K. Nishida, Y Hiraki, Y Tano, C. Shukunami
- Journal Title
  
  J. Cell Sci. 117
  
  Pages: 2731-2744
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Active proliferation of mesenchymal cells prior to the chondrogenic repair response in rabbit full-thickness defects of articular cartilage2004
- Author(s)
  H. Mizuta, S. Kudo, E. Nakamura, Y. Otsuka, K. Takagi, Y. Hiraki
- Journal Title
  
  Osteoarthritis Cartilage 12
  
  Pages: 586-596
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Nondestructive Isolation of Single Cultured Animal Cells by Femtosecond Laser-Induced Shockwave2004
- Author(s)
  Yoichiroh Hosokawa, Jyun-ichi Takabayahsi, Shigenoi Miura, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Journal Title
  
  Applied Physics A : Materials Science & Processing 79・4-6
  
  Pages: 795-798
- Data Source
  KAKENHI-PROJECT-16651067
[Journal Article] Nondestructive Isolation of Single Cultured Animal Cells by Femtosecond Laser-Induced Shockwave2004
- Author(s)
  Yoichiroh Hosokawa, Jyun-ichi Takabayashi, Shigenori Miura, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Journal Title
  
  Applied Physics A: Materials Science & Processing 79・4-6
  
  Pages: 795-798
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] 集光フェムト秒レーザー衝撃波を用いた単一細胞加工2004
- Author(s)
  細川陽一郎, 高林淳一, 宿南知佐, 開祐司, 増原宏
- Journal Title
  
  レーザー加工学会 11
  
  Pages: 190-192
- Data Source
  KAKENHI-PROJECT-16072211
[Journal Article] Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.
- Author(s)
  R. Itoh, S. Miura, S. Kondo, H. Sano, Y. Hiraki
- Journal Title
  
  J. Bone Miner. Metab. (印刷中)
- NAID
  10027845925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells.
- Author(s)
  K. Yukata, Y. Matsui, C. Shukunami, A. Takimoto, N. Hirohashi, O. Ohtani, T. Kimura, Y. Hiraki, N. Yasui
- Journal Title
  
  Tissue and Cell (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014046
[Journal Article] Non-destructive micro-patterning of protein crystals by focused femtosecond laser
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Yuji Hiraki, Hajime Mori, Hiroshi Masuhara
- Journal Title
  
  SPIE Proceeding (印刷中)
- Data Source
  KAKENHI-PROJECT-16651067
[Patent] テノモジュリンを有効成分とする腱断裂性疾患治療剤2007
- Inventor(s)
  福田恵一、開祐司、宿南知佐
- Industrial Property Rights Holder
  福田恵一、開祐司、宿南知佐
- Filing Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-17014046
[Patent] 微小粒子の配置方法2006
- Inventor(s)
  細川陽一郎, 増原宏, 開祐司, 南知佐
- Industrial Property Rights Holder
  大阪大学, 京都大学
- Industrial Property Number
  2005-089697
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-16651067
[Presentation] 腱板付着部損傷後修復過程におけるScx/Sox9共発現細胞の参画と組織形態の関連（シンポジウム：Bone tendon interface）2017
- Author(s)
  徳永琢也, 井手尾勝政, 米満龍史, 有村仁志, 唐杉樹, 井手淳二, 宿南知佐, 開祐司, 水田博志
- Organizer
  第32回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-16K20062
[Presentation] 内軟骨性骨形成におけるコンドロモジュリン-IのN末端領域の切断による不活性化2011
- Author(s)
  滝本晶、宿南知佐、三浦重徳、近藤淳、佐野寛子、田中英之、開祐司
- Organizer
  第12回運動器科学研究会
- Place of Presentation
  高知
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-21510224
[Presentation] 間葉組織の血管化制御-血管侵入バリアーの形成-2010
- Author(s)
  開祐司
- Organizer
  がん特定研究5領域合同シンポジウム
- Place of Presentation
  学術総合センター(東京)
- Year and Date
  2010-01-15
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 間葉組織の血管化制御-血管侵入バリアーの形成-2010
- Author(s)
  開祐司
- Organizer
  がん特定研究5領域合同シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 結合組織の血管侵入抵抗性と軟骨形成.2010
- Author(s)
  開祐司
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 間充織凝集による軟骨形成と血管侵入抵抗性の獲得2010
- Author(s)
  滝本晶、開祐司、宿南知佐
- Organizer
  第42回日本結合組織学会学術大会・第57回マトリックス研究会大会合同学術集会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-21510224
[Presentation] 血管侵入抵抗性障壁を作る細胞外環境2009
- Author(s)
  開祐司
- Organizer
  第17回日本血管生物医学会
- Place of Presentation
  東京大学安田講堂(東京)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 血管侵入抵抗性障壁を作る細胞外環境.2009
- Author(s)
  開祐司
- Organizer
  第17回日本血管生物医学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2009-10-08
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 軟骨内骨化における血管侵入抵抗性の成立とコンドロモジュリンの作用.2008
- Author(s)
  開祐司
- Organizer
  第11回Vitamin K & Aging研究会
- Place of Presentation
  東京
- Year and Date
  2008-02-16
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 軟骨形成・維持とECM環境.2008
- Author(s)
  開祐司
- Organizer
  第29回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 結合組織の血管侵入抵抗性と軟骨形成2008
- Author(s)
  開祐司
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-19510217
[Presentation] 結合組織の血管侵入抵抗性と軟骨形成2008
- Author(s)
  開祐司
- Organizer
  第23回日本整形外科学会基礎学術集会
- Place of Presentation
  京都
- Year and Date
  2008-10-23
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 骨・軟骨の形成と血管侵入抵抗性の成立.2008
- Author(s)
  開祐司
- Organizer
  第7回骨・軟骨広島フォーラム(特別講演)
- Place of Presentation
  広島
- Year and Date
  2008-02-14
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] Tissue-specific angiogenesis inhibitors in hypovascular connective tissues: chondromodulin-I and tenomodulin.2008
- Author(s)
  Y. Hiraki
- Organizer
  The U.S. -JAPAN Cooperative Cancer Research Program Workshop 2008
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 軟骨形成・維持とECM環境2008
- Author(s)
  開祐司
- Organizer
  第29回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19510217
[Presentation] 関節軟骨の変性と修復.2007
- Author(s)
  開祐司
- Organizer
  第4回六甲カンファランス
- Place of Presentation
  神戸
- Year and Date
  2007-09-02
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 血管新生抑制因子コンドロモジュリンIは正常弁に発現し弁の機能維持に働く.2007
- Author(s)
  伯野大彦、木村成卓、岡田保典、四津良平、小川聡、開祐司、福田恵一
- Organizer
  第28回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2007-08-02
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] Aging-related shift of the angiogenic balance switch2007
- Author(s)
  開祐司、宿南知佐
- Organizer
  第8回Aging Science Forum.
- Place of Presentation
  大阪
- Year and Date
  2007-04-05
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] A potential role of decidual chondromodulin-I in the control of cell migration and invasion of trophoblast giant cells2007
- Author(s)
  S. Miura, C. Shukunami, Y. Nishizaki, Y. Hiraki
- Organizer
  The 21st Century COE Symposium for Integration of Transplantation Therapy and Regenerative Medicine
- Place of Presentation
  京都
- Year and Date
  2007-06-29
- Data Source
  KAKENHI-PROJECT-19510217
[Presentation] Chondromodulin-Iの血管内皮細胞に対する遊走阻害活性2007
- Author(s)
  三浦重徳、宿南知佐、開祐司
- Organizer
  第8回運動器科学研究会
- Place of Presentation
  徳島
- Year and Date
  2007-08-24
- Data Source
  KAKENHI-PROJECT-19510217
[Presentation] "Non-destructive micro-patterning of living cells and protein crystals by focused femtosecond laser" (Invited)2006
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Yuji Hiraki, Hajime Mori, Hiroshi Masuhara
- Organizer
  Photonics West 2006
- Place of Presentation
  San Jose, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Biomaterial Injection to Single Animal Cell by Focused Femtosecond Laser2006
- Author(s)
  Seriya Iguchi, Ryohei Yasukuni, Yoichiroh Hosokawa, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  The 4th International Congress on Laser Advanced Materials Processing (LAMP2006)
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Laser Micro-injection of Sugar Chain into Single Animal Cell: Application of Femtosecond Laser Ablation in Solution2006
- Author(s)
  Yoichiroh Hosokawa, Seriya Iguchi, Ryohei Yasukuni, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  XXIst IUPAC Symposium on Photochemistry
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Realignment Process of Actin Stress Fiber Dissected by Focused Femtosecond Laser2006
- Author(s)
  Ryohei Yasukuni, Jean-Alexis Spitz, Rachel Meallet-Renault, Yoichiroh Hosokawa, Tsuyoshi Asahi, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  5th International Conference on Photo-Excited Processes and Applications
- Place of Presentation
  Charlottesville, Virginia, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Femtosecond Laser-induced Ablation and Contraction Dynamics of Actin Filaments in Mouse NIH3T3 Fibroblast Cells2006
- Author(s)
  Ryohei Yasukuni, Yoichiroh Hosokawa, Tsuyoshi Asahi, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  XXIst IUPAC Symposium on Photochemistry
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Laser Micro-injection of Sugar Chain into Single Animal Cell : Application of Femtosecond Laser Ablation in Solution2006
- Author(s)
  Yoichiroh Hosokawa, Seriya Iguchi, Ryohei Yasukuni, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  XXIst IUPAC Symposium on Photochemistry
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Realignment Process of Actin Stress Fiber Dissected by Focused Femtosecond Laser2006
- Author(s)
  Ryohei Yasukuni, Jean-Alexis Spitz, Rachel Meallet-Renault, Yoichiroh Hosokawa, Tsuyoshi Asahi, Chisa Shukunami, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  5th International Conference on Photo-Excited Processes and Applications
- Place of Presentation
  Charlottesville, Virginia USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] 骨・軟骨の血管化制御.2006
- Author(s)
  宿南知佐、西崎有利子、近藤俊哉、開祐司
- Organizer
  2006年度農芸化学会シンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] Dissection of Biological Filaments by Femtosecond Laser Irradiation2006
- Author(s)
  Ryohei Yasukuni, Yoichiroh Hosokawa, Tsuyoshi Asahi, Yuji Hiraki, Hiroshi Masuhara
- Organizer
  The 4th International Congress on Laser Advanced Materials Processing (LAMP2006)
- Place of Presentation
  Kyoto, Japan
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Non-destructive micro-patterning of living cells and protein crystals by focused femtosecond laser (Invited)2006
- Author(s)
  Yoichiroh Hosokawa, Takahiro Kaji, Yuji Hiraki, Hajime Mori, Hiroshi Masuhara
- Organizer
  Photonics West 2006
- Place of Presentation
  San Jose, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] 間葉組織の血管化制御-the control of vascularity in mesenchymal tissues-2005
- Author(s)
  開祐司
- Organizer
  第6回Aging Science Forum
- Place of Presentation
  大阪
- Year and Date
  2005-04-09
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 軟骨細胞の分化と再生.2005
- Author(s)
  開祐司
- Organizer
  第6回運動器科学研究会
- Place of Presentation
  静岡
- Year and Date
  2005-08-27
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] Local deformation and regeneration processes of single animal cell by focused femtosecond laser beam2005
- Author(s)
  Y. Hosokawa, T. Tada, T. Asahi, H. Masuhara, C. Shukunami, Y. Hiraki
- Organizer
  The 8th International Conference on Laser Ablation
- Place of Presentation
  Banff, Canada
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] Impaired cartilage formation by blocking VEGF signaling with soluble Flt-1 during chick limb development2005
- Author(s)
  Aki Takimoto, Miwa Kakuhana, Yuji Hiraki, Masabumi Shibuya, Chisa Shukunami
- Organizer
  Gordon Research Conference on Biology and Pathology of Cartilage
- Place of Presentation
  Barga, Italy
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16072211
[Presentation] 軟骨由来血管新生抑制因子と骨・軟骨代謝.2005
- Author(s)
  開祐司
- Organizer
  第14回京都骨代謝研究会
- Place of Presentation
  京都
- Year and Date
  2005-11-10
- Data Source
  KAKENHI-PROJECT-17014046
[Presentation] 椎間板形成におけるPax1の役割
- Author(s)
  滝本晶, 開祐司, 宿南知佐
- Organizer
  第32回日本骨代謝学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-07-24 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-24300154

1. SUZUKI Fujio (40028717)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. INOUE Hiroyuki (90167271)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SHUKUNAMI Chisa (60303905)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
4. MASUHARA Hiroshi (60029551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. 滋野長平 (30170864)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 遠藤直人 (10251810)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KONDO Shunya (80362523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. KOKUBU Chikara (70379238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. KAWAKAMI Toru (70273711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKAGAWA Koichi (60227741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ASAHI Tsuyoshi (20243165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
12. IMAMOTO Yasushi (80263200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATO Yukio (10112062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TOKUNAGA Takuya (60759520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 池田恭治 (00222878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 飯田寛和 (60176047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 黒木登志夫 (90006073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 石川冬木 (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 樋野興夫 (90127910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 菊池章 (10204827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 宮園浩平 (90209908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐谷秀行 (80264282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 貝淵弘三 (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 山本雅 (40134621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 時野隆至 (40202197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 秋山徹 (70150745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 高橋雅英 (40183446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 田中信之 (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 武藤誠 (70281714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 堀井明 (40249983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 内田淳正 (40176681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 朔敬 (40145264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 林孝文 (80198845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 木村信 (80251825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 程くん (40207460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 依田浩子 (60293213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 三浦重徳 (70511244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. IDEO Katsumasa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
39. YONEMITSU Ryuji

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

HIRAKI Yuji 開 祐司

開 裕司 ヒラキ ユウジ

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Exploring the anchoring molecules and cleaving enzymes of Chondromodulin-I, a cartilage-derived angiogenesis inhibitorPrincipal Investigator

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The structural determination and anti-angiogenic activity of a Chondromodulin-I subtype that lacks the N-terminal domain.Principal Investigator

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The structural domains of Chondromodulin-I, an angiogenesis inhibitor, and their contribution to its bioactivityPrincipal Investigator

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Molecular basis of anti-angiogenic barriers in mesenchymal tissuesPrincipal Investigator

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間葉系組織構築を制御する増殖分化因子群Principal Investigator

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血管新生阻害因子コンドロモジュリン-Iの発現動態と抗腫瘍活性Principal Investigator

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軟骨の悪性腫瘍化と血管新生阻害因子コンドロモジュリン-1の役割Principal Investigator

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HIRAKI Yuji 開祐司

開裕司ヒラキユウジ