MIURA Shigenori 三浦重徳

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SHIGENORI MIURA 三浦重徳

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Researcher Number	70511244
Other IDs
Affiliation (Current)	2022: 東京大学, 大学院情報理工学系研究科, 特任准教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 東京大学, 生産技術研究所, 特任講師 2016 – 2018: 京都大学, ウイルス・再生医科学研究所, 助教 2017: 京都大学, 再生医科学研究所, 研究員 2014 – 2016: 京都大学, 再生医科学研究所, 助教 2015: 東京大学, 生産技術研究所, 研究員 2013: 東京大学, 生産技術研究所, 特任研究員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related Except Principal Investigator Intelligent mechanics/Mechanical systems / Biomolecular chemistry / Nano/Microsystems / Functional basic dentistry / Basic Section 57010:Oral biological science-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator マイクロ流体デバイス / MEMS / 力学刺激 / 流体シェアストレス / 微絨毛 / TRPV6 / マイクロ流路 / 流体せん断力 / BioMEMS / 再生医療 … More / メカニカルストレス / 伸展刺激 / ３次元血管網 / 胎盤バリア / カルシウムイオン / TRP channel / 流体シェア / シェアストレス / グルコーストランスポーター / 生体機能チップ / メカノバイオロジー / 胎盤 / organ-on-chip / メカノリスポンス / 組織形成 / 椎間板 / 線維輪 / 生体模倣デバイス / Pax1 / 硬節 / エンハンサー / ３次元培養 / 静脈弁 / 下肢静脈瘤 / 血管網 / 創薬 / Prox1 / 血管ネットワーク / 3次元血管モデル / 力学場再構成 / 管腔構造 / 脈動流 / 血管床 / 灌流 / オルガノイド / 人工血管ベッド / ３次元組織構築 … More Except Principal Investigator 再生医療 / マイクロ・ナノデバイス / 歯根 / マイクロデバイス / マイクロマシン / 細胞・組織 / 神経科学 / コンドロモジュリン-I / 血管新生抑制因子 / 軟骨 / 細胞外マトリックス / アンカー分子 / 切断酵素 / Chondromoduin-I / 軟骨マトリックス / コンドロモジュリン / エンドプロテアーゼ / 生体機能模倣 / 脂質 / 生体材料（リポソーム） / 合成生物学 / 膜性骨化 / Runx2 / ゲノム編集 / 点変異 / 歯学 / 骨形成 / 変異 / 腱 / 靱帯 / 細胞分化 / 幹細胞 / Scleraxis / Sox9 / 縫合部 / Sxleraxis / Enthesis / 靭帯 / 顎関節 / ヒトiPS由来心筋組織 / In vitro 組織成熟化 / 力学刺激 / ベイズ的最適化 / 画像処理 / in vitro組織成熟化 / 単一細胞イメージング / ベイズ推定 / iPS由来心筋組織 / 機械学習 Less

三次元組織の血管化と持続的な培養を実現する人工ヒト血管床の開発Principal Investigator
- Principal Investigator
  
  三浦重徳
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Development of the 3D intervertebral disc tissue model reconstituted with its precursor cells and the tissue-specific mechanical environmentPrincipal Investigator
- Principal Investigator
  
  Miura Shigenori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Efficient maturation of 3D tissues in vitro by intelligent mechanical stimuli
- Principal Investigator
  
  Onoe Hiroaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Keio University
In vitro venous valve formation by extracting and reconstructing the mechanical cues involved in the valve developmentPrincipal Investigator
- Principal Investigator
  
  Miura Shigenori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Fluorescent imaging and analysis of molecular biological properties of the cells that contribute to the integration of the skeletal components
- Principal Investigator
  
  Shukunami Chisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Hiroshima University
The mechano-response triggering microvilli formation and its roles in tissue formationPrincipal Investigator
- Principal Investigator
  
  MIURA Shigenori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
  Kyoto University
Establishment of a new mouse model of cledocranial dysplasia by TALEN mediated genome editing
- Principal Investigator
  
  Shukunami Chisa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Exploring the anchoring molecules and cleaving enzymes of Chondromodulin-I, a cartilage-derived angiogenesis inhibitor
- Principal Investigator
  
  Hiraki Yuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Kyoto University
Construction of vascularized nerve tissue by a 3D co-culture system consisting of cell microfibers
- Principal Investigator
  
  Negishi Midori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Intelligent mechanics/Mechanical systems
- Research Institution
  The University of Tokyo
Development of Assembled Cell Model by Using Liposome-Liposome Adhesions
- Principal Investigator
  
  OSAKI TOSHIHISA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nano/Microsystems
- Research Institution
  Kanagawa Academy of Science and Technology
Construction of a microfluidic system for the analysis of human blood-placental barrierPrincipal Investigator
- Principal Investigator
  
  SHIGENORI MIURA
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kyoto University
  The University of Tokyo

All 2022 2021 2020 2019 2017 2016 2014 Other

All Journal Article Presentation Book

[Book] 整形・災害外科, 連載企画「腱・靭帯研究のフロンティア」: 椎間板の形成と恒常性の維持2020
- Author(s)
  三浦重德, 宿南知佐
- Total Pages
  5
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-19K22954
[Book] Drug Delivery System 第34巻4号2019
- Author(s)
  三浦重德，竹内昌治
- Total Pages
  7
- Publisher
  じほうビジネスサービス
- Data Source
  KAKENHI-PROJECT-19H04440
[Journal Article] Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert2022
- Author(s)
  Shigenori Miura, Yuya Morimoto, Tomomi Furihata, Shoji Takeuchi
- Journal Title
  
  APL Bioengineering
  
  Volume: 6 Pages: 016103-016103
- DOI
  10.1063/5.0085564
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19887
[Journal Article] Microfluidic system for applying shear flow to endothelial cells on culture insert with collagen vitrigel membrane.2021
- Author(s)
  Morimoto, Y., Nagata, S., Matsumoto, M., Sugawara, K., Miura, S., and Takeuchi
- Journal Title
  
  Sensors and Actuators: B. Chemical
  
  Volume: 348 Pages: 130675-130675
- DOI
  10.1016/j.snb.2021.130675
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04440
[Journal Article] ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.2020
- Author(s)
  Shimizu, A., Goh,WH., Itai, S., Hashimoto, M., Miura, S. and Onoe, H.
- Journal Title
  
  Lab on a chip
  
  Volume: 20 Pages: 1917-1927
- DOI
  10.1039/d0lc00254b
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Journal Article] 腱・靱帯研究のフロンティア(11)「椎間板の形成と恒常性の維持」2020
- Author(s)
  三浦重徳、宿南知佐
- Journal Title
  
  整形・災害外科
  
  Volume: 63 (12) Pages: 1685-1689
- NAID
  40022415475
- Data Source
  KAKENHI-PROJECT-18H02966
[Presentation] Protein expression micro-scale mapping analysis of endothelial tissue in in vitro branched vascular model under mechanical stimuli.2022
- Author(s)
  Muramatsu, J., Shimizu, A., Hashimoto, M., Miura, S., and Onoe, H.
- Organizer
  MEMS2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Shape retaining and sacrificial molding fabrication method for ECM-based in vitro vascular model2021
- Author(s)
  J. Muramatsu, W. H. Goh, M. Hashimoto, S. Miura, A. Shimizu, K. Hashimoto, and H. Onoe
- Organizer
  MEMS2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Real-time single-cell-resolution observation of three-dimensional skeletal muscle tissues under mechanical stimuli2021
- Author(s)
  Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
- Organizer
  Japan Satellite Session, Mimics, and Microfluidics: Engineering Tools for Mechanobiology
- Data Source
  KAKENHI-PROJECT-19H01178
[Presentation] Real-time three-dimensional single-cell-resolution monitoring system for observation of dynamic cell behavior under mechanical stimuli2021
- Author(s)
  Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
- Organizer
  The 34th International Conference on Micro Electro Mechanical Systems (MEMS 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01178
[Presentation] Pulsatile flow analysis at branched point in ECM-based endothelial vascular model under mechanical stretch.2021
- Author(s)
  Muramatsu, J., Hashimoto, M., Miura, S., and Onoe, H.
- Organizer
  MicroTAS 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Real time three-dimensional single cell-resolution monitoring system for observation of dynamic cell behavior under mechanical stimuli.2021
- Author(s)
  K. Kasahara, Y. Kurashina, S. Miura, S. Miyata, and H. Onoe
- Organizer
  MEMS2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Real-time single-cell-resolution observation of three-dimensional skeletal muscle tissues under mechanical stimuli2021
- Author(s)
  K. Kasahara, Y. Kurashina, S. Miura, S. Miyata, H. Onoe
- Organizer
  MBI 3M satellite poster session in Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Shape retaining and sacrificial molding fabrication method for ECM-based in vitro vascular model.2021
- Author(s)
  J. Muramatsu, W. H. Goh, M. Hashimoto, S. Miura, A. Shimizu, K. Hashimoto, and H. Onoe
- Organizer
  MEMS2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] マイクロ流体デバイスを利用した生体組織モデルの開発2020
- Author(s)
  三浦重徳
- Organizer
  第64回日本薬学会　関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22954
[Presentation] in vitro 3次元組織培養のための伸展可能なECMマイクロ流体システム2019
- Author(s)
  清水あずさ、Goh Wei Huang、橋本道尚、三浦重徳、尾上弘晃
- Organizer
  第58回日本生体医工学会
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] 引張刺激環境下におけるin vitro3次元組織内細胞形態観察システム2019
- Author(s)
  笠原啓太郎，倉科佑太，三浦重徳，宮田昌悟，尾上弘晃
- Organizer
  化学とマイクロ・ナノシステム学会第39回研究会
- Data Source
  KAKENHI-PROJECT-19H01178
[Presentation] In vitro血管モデルにおける力学刺激と細胞応答の可視化2019
- Author(s)
  橋下健哉、清水あずさ、三浦重徳、尾上弘晃
- Organizer
  第10回マイクロ・ナノ工学シンポジウム
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] Shape deformation analysis of single cell in 3D tissue under mechanical stimuli2019
- Author(s)
  Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
- Organizer
  The 20th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H01178
[Presentation] マイクロ流体デバイスを用いた組織再構成アプローチによる生命現象の理解2019
- Author(s)
  三浦重徳
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22954
[Presentation] Stretching Motion-driven ECM-based Pulsatile Flow Generator for Mimicking Venous Blood Flow in vivo.2019
- Author(s)
  Shimizu, A., Goh, Wei H., Itai, S., Hashimoto, M., Miura, S., Onoe, H.
- Organizer
  MicroTAS 2019 Proceedings
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] ECM-based Stretchable Microfluidic System for in vitro 3D Tissue Culture.2019
- Author(s)
  A. Shimizu, J. Hashimoto, M. Hashimoto, S. Miura, H. Onoe
- Organizer
  Transducers 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H04440
[Presentation] 流体せん断力によるヒト胎盤バリア極性構造の形成2017
- Author(s)
  三浦重徳，佐藤幸治，根岸みどり，手島哲彦，竹内昌治
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K01353
[Presentation] マイクロ流体システムを用いたヒト胎盤バリアモデルの構築2017
- Author(s)
  三浦重徳，佐藤幸治，根岸みどり，手島哲彦，竹内昌治
- Organizer
  シンポジウム：細胞アッセイ技術の現状と将来
- Data Source
  KAKENHI-PROJECT-16K01353
[Presentation] 微絨毛形成を伴う細胞の力学刺激応答とその分子メカニズム2016
- Author(s)
  三浦重徳，佐藤幸治，根岸みどり，手島哲彦，竹内昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K01353
[Presentation] マイクロ流体システムを用いたヒト胎盤バリア極性構造の再構築2016
- Author(s)
  三浦重徳，佐藤幸治，根岸みどり，手島哲彦，竹内昌治
- Organizer
  化学とマイクロ・ナノシステム学会第33回研究会
- Place of Presentation
  東京
- Year and Date
  2016-04-25
- Data Source
  KAKENHI-PROJECT-16K01353
[Presentation] マイクロ流路デバイスを利用した血液－胎盤関門のin vitro再構築2014
- Author(s)
  三浦重徳、手島哲彦、竹内昌治
- Organizer
  日本再生医療学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-25750157
[Presentation] Reconstitution of the human placental barrier on a chip
- Author(s)
  S. Miura, T. Teshima, S. Takeuchi
- Organizer
  JST ERATO International Symposium on 3D Tissue Fabrication
- Place of Presentation
  Tokyo
- Year and Date
  2014-05-20 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25750157

1. Onoe Hiroaki (30548681)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. Shukunami Chisa (60303905)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. Negishi Midori (30300750)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 森本雄矢 (60739233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Hiraki Yuji (40144498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OSAKI TOSHIHISA (50533650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Yamamoto Takashi (90244102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Sakuma Tetsushi (90711143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Yuki Yoshimoto (40735304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 谷本幸太郎 (20322240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 倉科佑太 (40801535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 舟橋啓 (70324548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山田貴大 (20837736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 遠山周吾 (90528192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 藤田淳 (10306706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 聶銘昊 (40816485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAMANO Hiroshige

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKIMOTO Aki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 根岸みどり(加藤みどり)

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

MIURA Shigenori 三浦 重徳

SHIGENORI MIURA 三浦 重徳

Research Projects

Research Products

Co-Researchers

三次元組織の血管化と持続的な培養を実現する人工ヒト血管床の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the 3D intervertebral disc tissue model reconstituted with its precursor cells and the tissue-specific mechanical environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Efficient maturation of 3D tissues in vitro by intelligent mechanical stimuli

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vitro venous valve formation by extracting and reconstructing the mechanical cues involved in the valve developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Fluorescent imaging and analysis of molecular biological properties of the cells that contribute to the integration of the skeletal components

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechano-response triggering microvilli formation and its roles in tissue formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a new mouse model of cledocranial dysplasia by TALEN mediated genome editing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploring the anchoring molecules and cleaving enzymes of Chondromodulin-I, a cartilage-derived angiogenesis inhibitor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of vascularized nerve tissue by a 3D co-culture system consisting of cell microfibers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Assembled Cell Model by Using Liposome-Liposome Adhesions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of a microfluidic system for the analysis of human blood-placental barrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 整形・災害外科, 連載企画「腱・靭帯研究のフロンティア」: 椎間板の形成と恒常性の維持2020

Author(s)

Total Pages

Publisher

Data Source

[Book] Drug Delivery System 第34巻4号2019

Author(s)

Total Pages

Publisher

MIURA Shigenori 三浦重徳

SHIGENORI MIURA 三浦重徳