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MIURA Shigenori  三浦 重徳

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SHIGENORI MIURA  三浦 重徳

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Researcher Number 70511244
Other IDs
Affiliation (Current) 2022: 東京大学, 大学院情報理工学系研究科, 特任准教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 東京大学, 生産技術研究所, 特任講師
2016 – 2018: 京都大学, ウイルス・再生医科学研究所, 助教
2017: 京都大学, 再生医科学研究所, 研究員
2014 – 2016: 京都大学, 再生医科学研究所, 助教
2015: 東京大学, 生産技術研究所, 研究員
2013: 東京大学, 生産技術研究所, 特任研究員
Review Section/Research Field
Principal Investigator
Biomedical engineering/Biomaterial science and engineering / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related
Except Principal Investigator
Intelligent mechanics/Mechanical systems / Biomolecular chemistry / Nano/Microsystems / Functional basic dentistry / Basic Section 57010:Oral biological science-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords
Principal Investigator
マイクロ流体デバイス / MEMS / 力学刺激 / 流体シェアストレス / 微絨毛 / TRPV6 / マイクロ流路 / 流体せん断力 / BioMEMS / 再生医療 … More / メカニカルストレス / 伸展刺激 / 3次元血管網 / 胎盤バリア / カルシウムイオン / TRP channel / 流体シェア / シェアストレス / グルコーストランスポーター / 生体機能チップ / メカノバイオロジー / 胎盤 / organ-on-chip / メカノリスポンス / 組織形成 / 椎間板 / 線維輪 / 生体模倣デバイス / Pax1 / 硬節 / エンハンサー / 3次元培養 / 静脈弁 / 下肢静脈瘤 / 血管網 / 創薬 / Prox1 / 血管ネットワーク / 3次元血管モデル / 力学場再構成 / 管腔構造 / 脈動流 / 血管床 / 灌流 / オルガノイド / 人工血管ベッド / 3次元組織構築 … More
Except Principal Investigator
再生医療 / マイクロ・ナノデバイス / 歯根 / マイクロデバイス / マイクロマシン / 細胞・組織 / 神経科学 / コンドロモジュリン-I / 血管新生抑制因子 / 軟骨 / 細胞外マトリックス / アンカー分子 / 切断酵素 / Chondromoduin-I / 軟骨マトリックス / コンドロモジュリン / エンドプロテアーゼ / 生体機能模倣 / 脂質 / 生体材料(リポソーム) / 合成生物学 / 膜性骨化 / Runx2 / ゲノム編集 / 点変異 / 歯学 / 骨形成 / 変異 / 腱 / 靱帯 / 細胞分化 / 幹細胞 / Scleraxis / Sox9 / 縫合部 / Sxleraxis / Enthesis / 靭帯 / 顎関節 / ヒトiPS由来心筋組織 / In vitro 組織成熟化 / 力学刺激 / ベイズ的最適化 / 画像処理 / in vitro組織成熟化 / 単一細胞イメージング / ベイズ推定 / iPS由来心筋組織 / 機械学習 Less
  • Research Projects

    (11 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (19 People)
  •  三次元組織の血管化と持続的な培養を実現する人工ヒト血管床の開発Principal Investigator

    • Principal Investigator
      三浦 重徳
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  Development of the 3D intervertebral disc tissue model reconstituted with its precursor cells and the tissue-specific mechanical environmentPrincipal Investigator

    • Principal Investigator
      Miura Shigenori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokyo
  •  Efficient maturation of 3D tissues in vitro by intelligent mechanical stimuli

    • Principal Investigator
      Onoe Hiroaki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Keio University
  •  In vitro venous valve formation by extracting and reconstructing the mechanical cues involved in the valve developmentPrincipal Investigator

    • Principal Investigator
      Miura Shigenori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      The University of Tokyo
  •  Fluorescent imaging and analysis of molecular biological properties of the cells that contribute to the integration of the skeletal components

    • Principal Investigator
      Shukunami Chisa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Hiroshima University
  •  The mechano-response triggering microvilli formation and its roles in tissue formationPrincipal Investigator

    • Principal Investigator
      MIURA Shigenori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      The University of Tokyo
      Kyoto University
  •  Establishment of a new mouse model of cledocranial dysplasia by TALEN mediated genome editing

    • Principal Investigator
      Shukunami Chisa
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Hiroshima University
  •  Exploring the anchoring molecules and cleaving enzymes of Chondromodulin-I, a cartilage-derived angiogenesis inhibitor

    • Principal Investigator
      Hiraki Yuji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      Kyoto University
  •  Construction of vascularized nerve tissue by a 3D co-culture system consisting of cell microfibers

    • Principal Investigator
      Negishi Midori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Intelligent mechanics/Mechanical systems
    • Research Institution
      The University of Tokyo
  •  Development of Assembled Cell Model by Using Liposome-Liposome Adhesions

    • Principal Investigator
      OSAKI TOSHIHISA
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Nano/Microsystems
    • Research Institution
      Kanagawa Academy of Science and Technology
  •  Construction of a microfluidic system for the analysis of human blood-placental barrierPrincipal Investigator

    • Principal Investigator
      SHIGENORI MIURA
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Kyoto University
      The University of Tokyo

All 2022 2021 2020 2019 2017 2016 2014 Other

All Journal Article Presentation Book

  • [Book] 整形・災害外科, 連載企画「腱・靭帯研究のフロンティア」: 椎間板の形成と恒常性の維持2020

    • Author(s)
      三浦重德, 宿南知佐
    • Total Pages
      5
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-19K22954
  • [Book] Drug Delivery System 第34巻4号2019

    • Author(s)
      三浦重德,竹内昌治
    • Total Pages
      7
    • Publisher
      じほうビジネスサービス
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Journal Article] Functional analysis of human brain endothelium using a microfluidic device integrating a cell culture insert2022

    • Author(s)
      Shigenori Miura, Yuya Morimoto, Tomomi Furihata, Shoji Takeuchi
    • Journal Title

      APL Bioengineering

      Volume: 6 Pages: 016103-016103

    • DOI

      10.1063/5.0085564

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19887
  • [Journal Article] Microfluidic system for applying shear flow to endothelial cells on culture insert with collagen vitrigel membrane.2021

    • Author(s)
      Morimoto, Y., Nagata, S., Matsumoto, M., Sugawara, K., Miura, S., and Takeuchi
    • Journal Title

      Sensors and Actuators: B. Chemical

      Volume: 348 Pages: 130675-130675

    • DOI

      10.1016/j.snb.2021.130675

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Journal Article] ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch.2020

    • Author(s)
      Shimizu, A., Goh,WH., Itai, S., Hashimoto, M., Miura, S. and Onoe, H.
    • Journal Title

      Lab on a chip

      Volume: 20 Pages: 1917-1927

    • DOI

      10.1039/d0lc00254b

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Journal Article] 腱・靱帯研究のフロンティア(11)「椎間板の形成と恒常性の維持」2020

    • Author(s)
      三浦 重徳、宿南 知佐
    • Journal Title

      整形・災害外科

      Volume: 63 (12) Pages: 1685-1689

    • NAID

      40022415475

    • Data Source
      KAKENHI-PROJECT-18H02966
  • [Presentation] Protein expression micro-scale mapping analysis of endothelial tissue in in vitro branched vascular model under mechanical stimuli.2022

    • Author(s)
      Muramatsu, J., Shimizu, A., Hashimoto, M., Miura, S., and Onoe, H.
    • Organizer
      MEMS2022
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Shape retaining and sacrificial molding fabrication method for ECM-based in vitro vascular model2021

    • Author(s)
      J. Muramatsu, W. H. Goh, M. Hashimoto, S. Miura, A. Shimizu, K. Hashimoto, and H. Onoe
    • Organizer
      MEMS2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Real-time single-cell-resolution observation of three-dimensional skeletal muscle tissues under mechanical stimuli2021

    • Author(s)
      Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
    • Organizer
      Japan Satellite Session, Mimics, and Microfluidics: Engineering Tools for Mechanobiology
    • Data Source
      KAKENHI-PROJECT-19H01178
  • [Presentation] Real-time three-dimensional single-cell-resolution monitoring system for observation of dynamic cell behavior under mechanical stimuli2021

    • Author(s)
      Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
    • Organizer
      The 34th International Conference on Micro Electro Mechanical Systems (MEMS 2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01178
  • [Presentation] Pulsatile flow analysis at branched point in ECM-based endothelial vascular model under mechanical stretch.2021

    • Author(s)
      Muramatsu, J., Hashimoto, M., Miura, S., and Onoe, H.
    • Organizer
      MicroTAS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Real time three-dimensional single cell-resolution monitoring system for observation of dynamic cell behavior under mechanical stimuli.2021

    • Author(s)
      K. Kasahara, Y. Kurashina, S. Miura, S. Miyata, and H. Onoe
    • Organizer
      MEMS2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Real-time single-cell-resolution observation of three-dimensional skeletal muscle tissues under mechanical stimuli2021

    • Author(s)
      K. Kasahara, Y. Kurashina, S. Miura, S. Miyata, H. Onoe
    • Organizer
      MBI 3M satellite poster session in Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Shape retaining and sacrificial molding fabrication method for ECM-based in vitro vascular model.2021

    • Author(s)
      J. Muramatsu, W. H. Goh, M. Hashimoto, S. Miura, A. Shimizu, K. Hashimoto, and H. Onoe
    • Organizer
      MEMS2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] マイクロ流体デバイスを利用した生体組織モデルの開発2020

    • Author(s)
      三浦重徳
    • Organizer
      第64回日本薬学会 関東支部大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22954
  • [Presentation] in vitro 3次元組織培養のための伸展可能なECMマイクロ流体システム2019

    • Author(s)
      清水あずさ、Goh Wei Huang、橋本道尚、三浦重徳、尾上弘晃
    • Organizer
      第58回日本生体医工学会
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] 引張刺激環境下におけるin vitro3次元組織内細胞形態観察システム2019

    • Author(s)
      笠原啓太郎,倉科佑太,三浦重徳,宮田昌悟,尾上弘晃
    • Organizer
      化学とマイクロ・ナノシステム学会第39回研究会
    • Data Source
      KAKENHI-PROJECT-19H01178
  • [Presentation] In vitro血管モデルにおける力学刺激と細胞応答の可視化2019

    • Author(s)
      橋下健哉、清水あずさ、三浦重徳、尾上弘晃
    • Organizer
      第10回マイクロ・ナノ工学シンポジウム
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] Shape deformation analysis of single cell in 3D tissue under mechanical stimuli2019

    • Author(s)
      Keitaro Kasahara, Yuta Kurashina, Shigenori Miura, Shogo Miyata, Hiroaki Onoe
    • Organizer
      The 20th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01178
  • [Presentation] マイクロ流体デバイスを用いた組織再構成アプローチによる生命現象の理解2019

    • Author(s)
      三浦重徳
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K22954
  • [Presentation] Stretching Motion-driven ECM-based Pulsatile Flow Generator for Mimicking Venous Blood Flow in vivo.2019

    • Author(s)
      Shimizu, A., Goh, Wei H., Itai, S., Hashimoto, M., Miura, S., Onoe, H.
    • Organizer
      MicroTAS 2019 Proceedings
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] ECM-based Stretchable Microfluidic System for in vitro 3D Tissue Culture.2019

    • Author(s)
      A. Shimizu, J. Hashimoto, M. Hashimoto, S. Miura, H. Onoe
    • Organizer
      Transducers 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H04440
  • [Presentation] 流体せん断力によるヒト胎盤バリア極性構造の形成2017

    • Author(s)
      三浦重徳,佐藤幸治,根岸みどり,手島哲彦,竹内昌治
    • Organizer
      第16回日本再生医療学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-16K01353
  • [Presentation] マイクロ流体システムを用いたヒト胎盤バリアモデルの構築2017

    • Author(s)
      三浦重徳,佐藤幸治,根岸みどり,手島哲彦,竹内昌治
    • Organizer
      シンポジウム:細胞アッセイ技術の現状と将来
    • Data Source
      KAKENHI-PROJECT-16K01353
  • [Presentation] 微絨毛形成を伴う細胞の力学刺激応答とその分子メカニズム2016

    • Author(s)
      三浦重徳,佐藤幸治,根岸みどり,手島哲彦,竹内昌治
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K01353
  • [Presentation] マイクロ流体システムを用いたヒト胎盤バリア極性構造の再構築2016

    • Author(s)
      三浦重徳,佐藤幸治,根岸みどり,手島哲彦,竹内昌治
    • Organizer
      化学とマイクロ・ナノシステム学会第33回研究会
    • Place of Presentation
      東京
    • Year and Date
      2016-04-25
    • Data Source
      KAKENHI-PROJECT-16K01353
  • [Presentation] マイクロ流路デバイスを利用した血液-胎盤関門のin vitro再構築2014

    • Author(s)
      三浦重徳、手島哲彦、竹内昌治
    • Organizer
      日本再生医療学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-25750157
  • [Presentation] Reconstitution of the human placental barrier on a chip

    • Author(s)
      S. Miura, T. Teshima, S. Takeuchi
    • Organizer
      JST ERATO International Symposium on 3D Tissue Fabrication
    • Place of Presentation
      Tokyo
    • Year and Date
      2014-05-20 – 2014-05-21
    • Data Source
      KAKENHI-PROJECT-25750157
  • 1.  Onoe Hiroaki (30548681)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 2.  Shukunami Chisa (60303905)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  Negishi Midori (30300750)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  森本 雄矢 (60739233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Hiraki Yuji (40144498)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OSAKI TOSHIHISA (50533650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Yamamoto Takashi (90244102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Sakuma Tetsushi (90711143)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Yuki Yoshimoto (40735304)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  谷本 幸太郎 (20322240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  倉科 佑太 (40801535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  舟橋 啓 (70324548)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  山田 貴大 (20837736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  遠山 周吾 (90528192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  藤田 淳 (10306706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  聶 銘昊 (40816485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HAMANO Hiroshige
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKIMOTO Aki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  根岸 みどり(加藤みどり)
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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