FUNAKOSHI Hiroshi 船越洋

… Alternative Names

船越洋フナコシヒロシ

FUNAKOSHI HIROSHI 船越洋

舟越洋フナコシヒロシ

Less

Researcher Number	40273685
Other IDs
External Links
Affiliation (Current)	2025: 旭川医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2017: 旭川医科大学, 医学部, 教授 2015: 旭川医科大学, 医学部, 教授 2013: 旭川医科大学, 教育研究推進センター, 教授 2011 – 2013: 旭川医科大学, 医学部, 教授 2010 – 2011: 大阪大学, 医学系研究科, 准教授 … More 2007: Osaka University, Graduate School of Medicine, Associate Professor 2007: Osaka University, Graduate School of Medicine, Associate Professor 2006: 大阪大学, 大学院医学系研究科, 助教授 2001 – 2006: 大阪大学, 医学系研究科, 助教授 2005: Osaka University, Department of Biochemistry and Molecular Biology, Associate professor, 大学院・医学研究科, 助教授 2004: 大阪大学, 大学院・医学系研究科, 助教授 1999 – 2001: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 1996 – 1998: 大阪大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Pathological medical chemistry Except Principal Investigator Functional biochemistry / Neurology / Pathological medical chemistry / General medical chemistry / Neurophysiology / General neuroscience / Neuroscience in general … More / Rehabilitation science/Welfare engineering / General medical chemistry / Neuroscience in general / Biological Sciences Less
Keywords	Principal Investigator HGF / c-Met / トランスジェニックマウス / 神経変性疾患 / 神経栄養因子 / HLP / Gas6 / 筋萎縮性側索硬化症(ALS) / Ron / Sky … More / 遺伝子治療 / 運動ニューロン / neurotrophic / HGF-like protein(HLP) / Transgenic mice / neuron / HGF-like Protein (HLP) / 肝細胞増殖因子(HGF) / 筋萎縮性側索硬化症 / 肝細胞増殖因子 / tyrosine kinase / Axl / Molecular cloning / ALS / 神経 / Neurotrophic / Neurodegenerative disease / ミクログリア / Protein S / c-Mer / ウイルスベクター / 再生・修復 / 運動神経 / 抗アポトーシス / クローニング / ニューロン / チロシンキナーゼ型受容体 / トランスジェニック / transgenic / Regenerative Medicine / Nervous System / オリゴデンドロサイト / 脳虚血 / リコンビナント蛋白質 / neurodegeneration / microglia / HGF-like Protein(HLP) / HFG / 高次脳機能 / Glia / Neurons / Amyotrophic lateral sclerosis (ALS) / パーキンソン病 / Scavenger receptor / Motor neurons / Amyotrophic Lateral Sclerosis(ALS) / Hepatocyte Growth Factor(HGF) / neurodegenerative disease / neurotrophic factor / Hepatocyte growth factor / survival / ProteinS / tyrosine kinase receptor / 精神神経疾患 / トリプトファン 2,3-ジオキシゲナーゼ / トリプトファン2,3-ジオキシゲナーゼ / セロトニン / トリプトファン / Tryptophan / ノックアウトマウス（KOマウス） / キヌレニン（KYN） / Indoleamine dioxygenase / Tryptophan dioxygenase / トリプトファン（Trp） / TDO / ノックアウトマウス / 代謝 / 情動 / キヌレニン / indoleamine dioxygenase / tryptophan dioxygenase / tryptophan / Hepatocyte growth factor (HGF) / c-MeT / グルタミン酸 / SRCL / スカベンジャー受容体 / 海馬 / synthetic neurotrophic factor … More Except Principal Investigator HGF / c-Met / 肝細胞増殖因子 / NK4 / LIMキナーゼ / 血管新生 / HGFアンタゴニスト / TGF-β / 再生医学 / トランスジェニックマウス / 転移 / 神経栄養因子 / c-met / 浸潤・転移 / 遺伝子治療 / 心筋梗塞 / 腫瘍血管新生 / 慢性腎不全 / 肝硬変 / MPTP / パーキンソン病 / Kremen / 組織線維化 / 組織再生 / Regenerative Medicine / Organ Protection / Repair / Regeneration / 心筋症 / 病理発生 / 抗線維化 / 再生医療 / 臓器保護 / 再生・修復 / metastasis / 癌治療 / タウ蛋白質 / クリングルドメイン / 浸潤 / 制癌 / 筋線維芽細胞 / 脳虚血 / 肺線維症 / 形態形成 / Sky / 劇症肝炎 / 脂肪肝 / GABA作動性経路 / ウイルスベクター / 視蓋脊髄路 / 脳深部刺激 / コリン作動性ニューロン / 中脳歩行誘発野 / 歩行誘発野 / 筋緊張 / 予期的姿勢調節 / 姿勢反射 / 姿勢筋緊張 / 脚橋被蓋核 / GABA作動性投射 / 黒質網様部 / 前庭脊髄路 / 網様体脊髄路 / 歩行 / 姿勢制御 / 学習記憶機能 / タウ蛋白 / タウオパチー / muscle weakness / muscle atrophy / neurotrophic factor / CAG repeat / androgen receptor / transgenic mouse / hepatocyte erowth factor / spinal and bulbar muscular atrophy / ダブルトランスジェニックマウス / ドランスジェニックマウス / 筋力低下 / 筋萎縮 / CAGリピート / アンドロゲン受容体 / 球脊髄性筋萎縮症 / Retrovirus vector / Neuronal stem cell / Hepatocyte growth factor / Regeneration medicine / Parkinson's disease / 猿 / レトロウイルス / MTPT / 幹細胞 / レトロウイルスベクター / 神経幹細胞 / Self-repair System / Extra-cellular Matrix / Myofibroblasts / Anti-fibrosis System / Chronic Organ Failure / 慢性疾患 / 慢性臓器疾患 / 抗線維化機構 / 自己修復システム / 細胞外マトリックス / 筋繊維芽細胞 / 抗繊維化機構 / 慢性臓器不全 / pancreatic cancer / tumor angiogenesis / angiogenesis / kringle domain / 制癌剤 / クリングル / HGT / 膵癌 / Cardiomyopathy / Chronic renal failure / Liver cirrhosis / TGF-beta1 / Anti-fibrosis / 難治性臓器疾患 / 線維性疾患 / 再生 / TGF-β1 / Regenerative Practice / LIM-kinase / Tumor Suppression / ES細胞 / ノックアウトマウス / 筋萎縮性側索硬化症 / 神経 / 運動神経 / 抗アポトーシス / 筋萎縮性側素硬化症 / transgenic mice / brain ischemia / gene therapy / cardiac infarction / chronic renal failure / cirrhosis / fatty liver / 湿潤・転移 / 腎臓 / 神経発生 / 肺 / 器官形成 / Gas6 / Bcl-xl / 肝細胞アポトーシス / invasion / tumor-stromal interaction / tumor / HGF antagonist / レセプター / サイトカイン / 増殖因子 / 癌浸潤・転移 / 腫瘍 / 癌細胞 / コラーゲンゲル内浸潤 / 基底膜浸潤 / 浸潤・転移抑制剤 / 癌-間質相互作用 / 腫瘍・癌 / ストレッチ / 脱神経筋 / リハビリテーション / LAR / HGFレセプター / 最終分化 / 成熟肝細胞 / DNA合成 / サイクリンE1 / サイクリンD1 / プロリン / 細胞密度依存性 / TDO / 成熟幹細胞 / 細胞内シグナル伝達 / 長期増強現象 / アルツハイマー病 / 細胞骨格 / がん悪性化 / 上皮・間葉相互作用 / 線維症 / 血管新生阻害 / プロテインキナーゼ / ウィリアム症候群 / POZドメイン / yeast two-hybrid / ニューロン / 脳梗塞 / インジュリン / c-sea / Ron / HLP / 上皮-間葉相互作用 / Met / Fas / 浸潤・転移阻止 / 器官再生 Less

Mechanisms of postural control operated by the basal ganglia, brainstem and spinal cord
- Principal Investigator
  
  Takakusaki Kaoru
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Asahikawa Medical College
Study of combined effect of hepatocyte growth factor and mechanical stretching to the peripheral nerve injured muscle
- Principal Investigator
  
  TANAKA Shoji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kanazawa University
Study on the therapeutic effects of hepatocyte growth factor on tauopathies using transgenic mice overexpressing mutated human tau.
- Principal Investigator
  
  Keiichi KADOYAMA
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Himeji Dokkyo University
Molecular dissection of tryptophan metabolism in emotional behavior and its related is diseases.Principal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Asahikawa Medical College
Analysis of molecular mechanisms that reciprocally regulate growth and differentiation of mature hepatocytes
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Analysis for the therapeutic effect of hepatocyte factor on learning and memory dysfunction in the mouse model of Alzheimer's Disease.
- Principal Investigator
  
  KADOYAMA Keiichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Himeji Dokkyo University
Role of HGF in the nervous systemPrincipal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Development of therapies in polyglutamine diseases using hepatocyte growth factor (HGF)
- Principal Investigator
  
  ADACHI Hiroaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Enhancement of adult neurogenesis for Parkisnon's diseased primate models
- Principal Investigator
  
  MOCHIZUKI Hideki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Juntendo University
Neurotrophic role of hepatocytes growth factor (HGF) and its family member in the nervous systemPrincipal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
HGFおよびそのフアミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Molecular Basis of Anti-fibrosis via Destruction of an Organ Self-repair System
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
HGF family that includes HGF & HLP/MSP as a novel neurotrophic familyPrincipal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾悪への適用Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
海馬及い運動ニューロン生存を担う新規神経栄養因子の探索とその機能解析Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
上皮・間葉相互作用によるがん悪性化の分子機構とその制御
- Principal Investigator
  
  中村敏一
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Functional analysis of HGF and its family member (HLP): from the basic to the potential application to neural diseasesPrincipal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
海馬及び運動ニューロン生存を担う新規神経栄養因子の探索とその機能解析Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Studies on Tissue Morphogenesis, Organogenesis and Repair by HGF
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Anti-fibrogenic analysis of HGF in intractable organ failures: Clinical potential of HGF as regenerative therapy
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
Vascular regulation by kringles of HGF and molecular cloning of a novel kringle-containing protein
- Principal Investigator
  
  MATSUMOTO Kunio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
海馬及び運動ニューロン生存を担う新規神経栄養因子の探索とその機能解析Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Molecular cloning and characterization of HGF family members with neurotrophic activitiesPrincipal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
海馬及び運動ニューロン生存を担う新規神経栄養因子の探索と機能解析Principal Investigator
- Principal Investigator
  
  船越洋
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
LIMキナーゼの分子細胞生物学的研究ならびに遺伝子欠損マウス作製による機能解析
- Principal Investigator
  
  松本邦夫
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
HGFによる脳神経系の生存維持とHGFからみた神経変性疾患の病態解析
- Principal Investigator
  
  松本邦夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Molecular and cellular biological analyzes of morphogenesis modulated by HGF
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Osaka University
Functional analysis of the novel brain-specific receptor tyrosine kinase "Sky"Principal Investigator
- Principal Investigator
  
  FUNAKOSHI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
Inhibitory effects of HGF antagonist on invasion/metastasis of tumor cells.
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University
HGFならびにLIMキナーゼによる高次細胞機能の調節とがん特性の研究
- Principal Investigator
  
  NAKAMURA Toshikazu
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University

All 2014 2013 2012 2011 2010 2009 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Clinical Neurosci.2007
- Author(s)
  船越洋、ほか.
- Publisher
  HGFの神経疾患治療効果.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Book] 神経変性疾患のサイエンスThe Fronders in Medical Sciences (高橋良輔編)南山堂2007
- Author(s)
  船越洋、ほか.
- Publisher
  第21章神経栄養因子の多様な機能と神経変性疾患への臨床適用の可能性.
- Data Source
  KAKENHI-PROJECT-18500294
[Book] Clinical Neurosci.2007
- Author(s)
  船越洋、ほか.
- Publisher
  HGFの神経疾患治療効果と神経保護作用機序.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Book] Brain and Nerve-神経研究の進歩2007
- Author(s)
  船越洋、ほか.
- Publisher
  ALSと神経栄養因子-新規神経栄養因子・神経再生因子としてのHGF.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Book] 難病と在宅ケア2007
- Author(s)
  船越洋、ほか.
- Publisher
  ALSの新しい治療薬としてのHGFの研究.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Book] 神経変性疾患のサイエンス The Frontiers in Medical Sciences (高橋良輔編) 南山堂2007
- Author(s)
  船越洋、ほか.
- Publisher
  第21章神経栄養因子の多様な機能と神経変性疾患への臨床適用の可能性.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Book] 肝細胞増殖因子(HGF)、広範囲血液・尿化学検査免疫学的検査(第6版)2005
- Author(s)
  大谷若菜, 船越洋, 中村敏一
- Total Pages
  7
- Publisher
  日本臨床社(東京)
- Data Source
  KAKENHI-PROJECT-14207005
[Book] 肝細胞増殖因子(HGF), 広範囲血液・尿化学検査免疫学的検査(第6版)2005
- Author(s)
  大谷若菜, 船越洋, 中村敏一
- Total Pages
  7
- Publisher
  日本臨床社(東京)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207005
[Journal Article] Contributions of Tryptophan 2,3-dioxygenase and Indoleamine 2,3-dioxygenase to the Conversion of D-Tryptophan to Nicotinamide Analyzed by using Tryptophan 2,3-dioxygenase -Knockout Mice2014
- Author(s)
  Maeta A, Sano M, Fukuwatari T, Funakoshi H, Nakamura T, and Shibata K
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Aryl hydrocarbon receptor control of a disease tolerance defense pathway2014
- Author(s)
  Puccetti P, Gargaro M, Pallotta M, Matino D, Vacca C, Volpi C, Belladonna M, Orabona C, Bianchi R, Grohmann U, Fallarino F, Iannitti R, Tissi L, Zelante T, Romani L, Servillo G, Brunacci C, Fazia MD, Piobbico D, Bessede A, Bicciato S, Mazza E, Macchiarulo A, Lanz T, Platten M, Funakoshi H et al.
- Journal Title
  
  Nature
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Contributions of Tryptophan 2,3-dioxygenase and Indoleamine 2,3-dioxygenase to the Conversion of D-Tryptophan to Nicotinamide Analyzed by using Tryptophan 2,3-dioxygenase -Knockout Mice2014
- Author(s)
  Maeta A, Sano M, Fukuwatari T, Funakoshi H, Nakamura T, Shibata K
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 78 Issue: 5 Pages: 1-4
- DOI
  10.1080/09168451.2014.905185
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] The kynurenine pathway contributes to long-term neuropsychological changes in experimental pneumococcal meningitis.2014
- Author(s)
  Too LK, McQuillan J, Ball H, Kanai M, Nakamura T, Funakoshi H, McGregor I, Hunt N
- Journal Title
  
  Behavioural Brain Research
  
  Volume: in press Pages: 179-195
- DOI
  10.1016/j.bbr.2014.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article]2014
- Author(s)
  Bessede A, Gargaro M, Pallotta MT, Matino D, Servillo G, Brunacci C, Bicciato S, Mazza EM, Macchiarulo A, Vacca C, Iannitti R, Tissi L, Volpi C, Belladonna ML,Orabona C, Bianchi R, Lanz TV, Platten M, Della Fazia MA, Piobbico D, Zelante T, Funakoshi H, et al
- Journal Title
  
  Nature
  
  Volume: 511 Issue: 7508 Pages: 184-190
- DOI
  10.1038/nature13323
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Tryptophan-restriction diets help to maintain L-tryptophan homeostasis in tryptophan 2,3-dioxygenase knockout mice2013
- Author(s)
  Akihiro Maeta, Tsutomu Fukuwatari, Hiroshi Funakoshi, Toshikazu Nakamura, and Katsumi Shibata
- Journal Title
  
  International Journal of Tryptophan Research
  
  Volume: in press
- NAID
  120005293327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.2013
- Author(s)
  Terakata M, Fukuwatari T, Kadota E, Sano M, Kanai M, Nakamura T, Funakoshi H, Shibata K
- Journal Title
  
  J Nutr
  
  Volume: 143(7) Issue: 7 Pages: 1046-51
- DOI
  10.3945/jn.113.176875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Tryptophan-restriction diets help to maintain L-tryptophan homeostasis in tryptophan 2,3-dioxygenase knockout mice2013
- Author(s)
  Maeta A, Fukuwatari T, Funakoshi H, Nakamura T, Shibata K
- Journal Title
  
  Int J Tryptophan Res.
  
  Volume: 6(Suppl 1) Pages: 55-65
- DOI
  10.4137/ijtr.s12206
- NAID
  120005293327
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] te amount of niacin required for optimum growth in growing mice can be synthesized from L-tryptophan without tryptophan 2,3-dioxygenase.2013
- Author(s)
  Miki Terakata, Tsutomu Fukuwatari, Eri Kadota, Mitsue Sano, Masaaki Kanai, Toshikazu Nakamura, Hiroshi Funakoshi, Katsumi Shibata
- Journal Title
  
  Journal of Nutrition
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] 再生因子(HGF)の神経系における機能と神経再生医療への展開の可能性2012
- Author(s)
  船越洋、島田（大谷）若菜、角山圭一、加藤貴史、中村敏一、北村和也、中村雅也、戸山芳昭、岡野栄之、青木正志
- Journal Title
  
  人工血液
  
  Volume: 20 (1) Pages: 12-12
- Data Source
  KAKENHI-PROJECT-24500389
[Journal Article] Hepatocyte growth factor overexpression in the nervous system enhances learning and memory performance in mice2012
- Author(s)
  Kato T, Funakoshi H, Kadoyama K, Noma S, Kanai M, Ohya-Shimada W, Mizuno S, Doe N, Taniguchi T, Nakamura T
- Journal Title
  
  J. Neurosci. Res
  
  Volume: 90(9) Issue: 9 Pages: 1743-55
- DOI
  10.1002/jnr.23065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362, KAKENHI-PROJECT-23590458, KAKENHI-PROJECT-24500389, KAKENHI-PROJECT-24730636
[Journal Article] Overexpression of HGF attenuates the degeneration of Purkinje cells and Bergmann glia in a knockin mouse model of spinocerebellar ataxia type 72012
- Author(s)
  Noma S, Ohya-Shimada W, Kanai M, Ueda K, Nakamura T, Funakoshi H
- Journal Title
  
  Neurosci Res.(Corresponding author)
  
  Volume: 773(2) Pages: 115-121
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Hepatocyte growth factor overexpression in the nervous system enhances learning and memory performance in mice2012
- Author(s)
  Kato T, Funakoshi H, Kadoyama K, Noma S, Kanai M, Ohya-Shimada W, Mizuno S, Doe N, Taniguchi T, Nakamura T
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Hepatocyte growth factor (HGF) overexpression in the nervous system enhances learning and memory performance in mice2012
- Author(s)
  Kato T, Funakoshi H, Kadoyama K, Noma S, Kanai M, Ohya-Shimada W, Mizuno S, Doe N, Taniguchi T, Nakamura T
- Journal Title
  
  J. Neurosci. Res. (Corresponding authors)
  
  Volume: 90(9) Pages: 1743-1755
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Overexpression of HGF attenuates the degeneration of Purkinje cell sand Bergmann glia in a knockin mouse model of spinocerebellar ataxia type 72012
- Author(s)
  Noma S, Ohya-Shimada W, Kanai M, Ueda K, Nakamura T, Funakoshi H.
- Journal Title
  
  Neurosci. Res
  
  Volume: 73 Issue: 2 Pages: 115-121
- DOI
  10.1016/j.neures.2012.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079, KAKENHI-PROJECT-22659091, KAKENHI-PROJECT-23590362
[Journal Article] Therapeutic role of regenerative factor "HGF" in ALS and other neurodegenerative disorders2012
- Author(s)
  Funakoshi H, Nakamura T
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 52(11) Pages: 942-942
- NAID
  130004505219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Overexpression of HGF attenuates the degeneration of Purkinje cells and Bergmann glia in a knockin mouse model of spinocerebellar ataxia type 72012
- Author(s)
  Noma S, Ohya-Shimada W, Kanai M, Nakamura T, and Funakoshi H.
- Journal Title
  
  Neurosci Res.
  
  Volume: 73(2) Pages: 115-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Therapeutic Potential of Hepatocyte Growth Factor for Treating Neurological Diseases2011
- Author(s)
  Kadoyama K., Kadoyama K., Funakoshi H., Nakamura T., Sakaeda T.
- Journal Title
  
  Current Drug Therapy
  
  Volume: 19, 6(3) Pages: 7-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Strong neurogenesis, angiogenesis and anti-fibrosis of hepatocyte growth factor in rats brain after transient middle cerebral artery occlusion (tMCAO)2011
- Author(s)
  Shang J, Deguchi K, Ohta Y, Liu N, Zhang X, Tian F, Yamashita T, Ikeda Y, Matsuura T, Funakoshi H, Nakamura T, Abe K
- Journal Title
  
  J Neurosci Res
  
  Volume: 89(1) Pages: 86-95
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Strong neurogenesis, angiogenesis, synaptogenesis, and antifibrosis of hepatocyte growth factor in rats brain after transient middle cerebral artery occlusion.2011
- Author(s)
  J.Shang, K.Deguchi, Y.Ohta, N.Liu, X.Zhang, F.Tian, T.Yamashita, Y.Ikeda, T.Matsuura, H.Funakoshi, T.Nakamura, K.Abe
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 89 Pages: 86-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Hepatocyte Growth Factor (HGF): Neurotrophic Functions and Therapeutic Implications for Neuronal Injury/Diseases2011
- Author(s)
  Funakoshi H., and Nakamura T
- Journal Title
  
  Current Signal Transduction Therapy
  
  Volume: 6 Pages: 156-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Modulation of Tryptophan Metabolism, Promotion of Neurogenesis and Alteration of Anxiety-Related Behavior in Tryptophan 2, 3-Dioxygenase-Deficient Mice2011
- Author(s)
  H. Funakoshi, M. Kanai and T. Nakamura.
- Journal Title
  
  Int. J. Trp. Res
  
  Volume: 4 Pages: 7-18
- DOI
  10.4137/ijtr.s5783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Therapeutic potential of hepatocyte growth factor for treating neurological diseases.2011
- Author(s)
  Kadoyama K, Funakoshi H, Nakamura T, Sakaeda T
- Journal Title
  
  Cur.Drug Ther. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500295
[Journal Article] Strong neurogenesis, angiogenesis, synaptogenesis, and antifibrosis of hepatocyte growth factor in rats brain after transient middle cerebral artery occlusion.2011
- Author(s)
  Shang J, Deguchi K, Ohta Y, Liu N, Zhang X, Tian F, Yamashita T, Ikeda Y, Matsuura T, Funakoshi H, Nakamura T, Abe K.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 89(1) Pages: 86-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Hepatocyte Growth Factor(HGF): Neurotrophic Functionsand Therapeutic Implications for NeuronalInjury/ Diseases2011
- Author(s)
  Funakoshi H and Nakamura T.
- Journal Title
  
  Curr. Signal Transduct. Ther
  
  Volume: 6 Issue: 2 Pages: 156-167
- DOI
  10.2174/157436211795659982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Modulation of Tryptophan Metabolism, promotion　of neurogenesis and Alteration of Anxiety-Related Behavior in Tryptophan 2,3-Dioxygenase-Deficient Mice2011
- Author(s)
  Funakoshi H., Kanai M., and Nakamura T.
- Journal Title
  
  International Journal of Tryptophan Research
  
  Volume: 4 Pages: 7-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Human Hepatocyte Growth Factor Promotes Functional Recovery in Primates after Spinal Cord Injury2011
- Author(s)
  Kitamura K, Fujiyoshi K, Yamane J, Toyota F, Hikishima K, Nomura T, Funakoshi H, Nakamura T, Aoki M, Toyama Y, Okano H, Nakamura M.
- Journal Title
  
  PLOS one
  
  Volume: 6 Issue: 11 Pages: e27706-e27706
- DOI
  10.1371/journal.pone.0027706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079, KAKENHI-PROJECT-23590362
[Journal Article] Human hepatocyte growth factor promotes functional recovery in primates after spinal cord injury.2011
- Author(s)
  Kitamura K, Fujiyoshi K, Yamane J, Toyota F, Hikishima K, Nomura T, Funakoshi H, Nakamura T, Aoki M, Toyama Y, Okano H, Nakamura M.
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590362
[Journal Article] Expression of tryptophan 2, 3-dioxygenase in mature granule cells of the adult mouse dentate gyrus2010
- Author(s)
  K. Ohira, H. Hagihara. K. Toyama, K. Takao, M. Kanai, H. Funakoshi, T. Nakamura and T. Miyakawa
- Journal Title
  
  Mol. Brain 3
  
  Volume: 26 Issue: 1
- DOI
  10.1186/1756-6606-3-26
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Implication of Tryptophan 2,3-dioxygenase and its novel variants in the hippocampus and cerebellum during the developing and adult brain.2010
- Author(s)
  M.Kanai, H.Funakoshi, T.Nakamura
- Journal Title
  
  Int.J.Tryptophan Res.
  
  Volume: 3 Pages: 141-149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Antiapoptotic and antiautophagic effects of glial cell line-derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats.2010
- Author(s)
  J.Shang, K.Deguchi, T.Yamashita, Y.Ohta, H.Zhang, N.Morimoto, N.Liu, X.Zhang, F.Tian, T Matsuura, H.Funakoshi, T.Nakamura, K.Abe
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 88 Pages: 2197-2206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Hepatocyte growth factor inhibits CNS gutoimunity by inducing tolerogenic dendritic cells and CD25^+Fox3^+ regulatory T cells2010
- Author(s)
  M.Benkhoucha, M,-L.Santiago-raber, G Achneiter, m Choffon, H.Funakoshi, T Nakamura, P.Lalive
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 107 Pages: 6424-6429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyros.2010
- Author(s)
  K.Ohira, H.Hagihara.K.Toyama, K.Takao, M.Kanai, H.Funakoshi, T.Nakamura, T.Miyakawa
- Journal Title
  
  Mol.Brain
  
  Volume: 3 Pages: 26-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Implication of Tryptophan 2, 3-dioxygenase and its novel variants in the hippocampus and cerebellum during the developing and adult brain2010
- Author(s)
  M. Kanai, H. Funakoshi and T. Nakamura.
- Journal Title
  
  Int. J. Tryptophan Res.
  
  Volume: 3 Pages: 141-149
- DOI
  10.4137/ijtr.s4372
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Identification and characterization of novel variants of the tryptophan 2, 3-dioxygenase gene : Differential regulation in the mouse nervous system during development2009
- Author(s)
  M. Kanai, T. Nakamura and H. Funakoshi.
- Journal Title
  
  Neurosci. Res.
  
  Volume: 64 Issue: 1 Pages: 111-117
- DOI
  10.1016/j.neures.2009.02.004
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Tryptophan 2, 3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice2009
- Author(s)
  M. Kanai, H. Funakoshi, H. Takahashi, T. Hayakawa. S. Mizuno, K. Matsumoto, and T. Nakamura.
- Journal Title
  
  Mol. Brain
  
  Volume: 2 Issue: 1 Pages: 8-8
- DOI
  10.1186/1756-6606-2-8
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of ALS.2009
- Author(s)
  K.Kadoyama, H.Funakoshi, W.Ohya-Shimada, T.Nakamura, K.Matsumoto, S.Matsuyama, T.Nakamura
- Journal Title
  
  Neurosci.Res. 65
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Differing responses of satellite cell activity to exercise training in rat skeletal muscle.2009
- Author(s)
  S.Tanaka, T.Miyata, T.Fujita, E.Kawahara, K.Tachino, H.Funakoshi, T.Nakamura
- Journal Title
  
  J.Phys.Ther.Sci. 21
  
  Pages: 141-145
- NAID
  10025401469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Differing responses of satellite cell activity to exercise training in rat skeletal muscle2009
- Author(s)
  S. Tanaka, T. Miyata, T. Fujita, E. Kawahara, K. Tachino, H. Funakoshi and T. Nakamura.
- Journal Title
  
  J. Phys. Ther. Sci.
  
  Volume: 21 Pages: 141-145
- NAID
  10025401469
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of a transgenic mouse model of ALS.2009
- Author(s)
  Kadoyama K, Funakoshi H, Ohya-Shimada W, Nakamura T, Matsumoto K, Matsuyama S, Nakamura T
- Journal Title
  
  Neurosci.Res. 65
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500295
[Journal Article] Disease-dependent reciprocal phosphorylation of serine and tyrosine residues of c-Met/HGF receptor contributes disease retardation of atransgenic mouse model of ALS.2009
- Author(s)
  Keiichi Kadoyama, Hiroshi Funakoshi, Wakana Ohya-Shimada, Takahiro Nakamura, Kunio Matsumoto, Shogo Matsuyama, Toshikazu Nakamura
- Journal Title
  
  Neuroscience Research 65
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500295
[Journal Article] Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogeneisi and anxiety-related behavior in mice2009
- Author(s)
  M.Kanai, H.Funakoshi, H.Takahashi, T.Hayakawa. S.Mizuno, K.Matsumoto, T.Nakamura
- Journal Title
  
  Mol.Brain 2
  
  Pages: 8-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene : Differential regulation in the mouse nervous system during development.2009
- Author(s)
  M.Kanai, T.Nakamura, H.Funakoshi
- Journal Title
  
  Neurosci.Res. 64
  
  Pages: 111-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079
[Journal Article] HGF as an effective agent for ALS therapy2007
- Author(s)
  Funakoshi, H., et. al.
- Journal Title
  
  Nanbyou to zaitakukea
  
  Pages: 54-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] The Frontiers in Medical Sciences『神経変性疾患のサイエンス』2007
- Author(s)
  船越洋他
- Journal Title
  
  南山堂 (In press)
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] Chapter 21. Potential clinical application of multifunctional neurotrophic factors in neurodegenerative diseases2007
- Author(s)
  Funakoshi, H., et. al.
- Journal Title
  
  The Frontiers in Medical Sciences. (edt R. Takahashi)
  
  Pages: 217-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] ALSに対する新しい治療薬としてのHGF研究2007
- Author(s)
  船越洋他
- Journal Title
  
  難病と在宅ケア 6月号(In press)
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] HGFの神経保護作用機序2007
- Author(s)
  船越洋他
- Journal Title
  
  Clinical Neuroscience 25巻・6号(In press)
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] ALS and neurotrophic factors. HGF as a novel neurotrophic and neuroregenerative factor2007
- Author(s)
  Funakoshi, H., et. al.
- Journal Title
  
  Brain and Nerve 59
  
  Pages: 1195-1202
- NAID
  40015666103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] Molecular mechanism of HGF neuroprotective effect and therapeutic potential in neurodegenerative diseases2007
- Author(s)
  Funakoshi, H., et. al.
- Journal Title
  
  Clinical Neurosci
  
  Pages: 620-621
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] 神経変性疾患のサイエンスThe Frontiers2007
- Author(s)
  船越洋、ほか.
- Journal Title
  
  Medical Sciences(高橋良輔編)南山堂, 第21章神経栄養因子の多様な機能と神経変性疾患への臨床適用の可能性.
  
  Pages: 217-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] HGFの神経疾患治療効果2007
- Author(s)
  船越洋他
- Journal Title
  
  Clinical Neuroscience 25巻・5号(In press)
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] Therapeutic potential of HGF in neurodegenerative diseases2007
- Author(s)
  Funakoshi, H., et. al.
- Journal Title
  
  Clinical Neurosci
  
  Pages: 500-501
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Journal Article] Anxiolytic effect of hepatocyte growth factor infused into rat brain.2006
- Author(s)
  Isogawa K, Funakoshi H, 他5名
- Journal Title
  
  Neuropsychobiology 5(1)
  
  Pages: 34-38
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Effects of hepatocyte growth factor on signal-regulated kinase and hippocampal cell death forebrain ischemia.2006
- Author(s)
  Niimura M, Takagi N, Takagi K, Funakoshi H, Nakamura T, Takeo S
- Journal Title
  
  Eur J Pharmacol 535
  
  Pages: 114-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Prevention of apoptosis-inducing factor mechanism for protective effects of hepatocyte neuronal cell death in the hippocampus after transient forebrain ischemia.2006
- Author(s)
  Niimura M, Takagi N, Takagi K, Mizutani R, Ishihara N, Matsumoto K, Funakoshi H, Nakamura T, Takeo S
- Journal Title
  
  J Cereb Blood Flow Metab 1
  
  Pages: 1-1
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Novel therapeutic strategy for stroke in rats by bone marrow stromal cells and ex vivo HGF gene transfer with HSV-1 vector.2006
- Author(s)
  Zhao MZ, Funakoshi H, 他13名
- Journal Title
  
  J Cereb Blood Flow Metab 18
  
  Pages: 1-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Novel therapeutic strategy for stroke in rats by bone and ex vivo HGF gene transfer with HSV-1 vector.2006
- Author(s)
  Zhao MZ, Nonoguchi N, Ikeda N, Watanabe T, Furutama D, Miyazawa D, Funakoshi H, Kajimoto Y, Nakamura T, Dezawa M, Shibata MA, Otsuki Y, Coffin RS, Liu WD, Kuroiwa T, Miyatake SI
- Journal Title
  
  J Cereb Blood Flow Metab 18
  
  Pages: 1-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemiai2006
- Author(s)
  Nishimura M, Funakoshi H, 他7名
- Journal Title
  
  J Cereb Blood Flow Metab. 26(3)
  
  Pages: 1-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Effects of hepatocyte growth factor on phosphorylation of extracellular signal-regulated kinase and hippocampal cell death in rats with transient forebrain ischemia.2006
- Author(s)
  Nishimura M, Funakoshi H, 他7名
- Journal Title
  
  Eur J Pharmacol. 535
  
  Pages: 114-124
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons.2006
- Author(s)
  Ishihara N, Funakoshi H, 他8名
- Journal Title
  
  J Neurochem. 319(4)
  
  Pages: 1277-1286
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Anxiolytic effect of hepatocyte growth factor infused into rat brain.2005
- Author(s)
  K.Isogawa, J.Akiyama, K.Kodama, H.Matsushita, T.Tsutsumi, H.Funakoshi, T.Nakamura
- Journal Title
  
  Neuropsychobiology 51
  
  Pages: 34-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207005
[Journal Article] Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons.2005
- Author(s)
  Ishihara N, Takagi N, Niimura M, Takagi K, Nakano M, Tanonaka K, Funakoshi H, Matsumoto K, Nakamura T, Takeo S
- Journal Title
  
  J Neurochem. 319(4)
  
  Pages: 1277-1286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207005
[Journal Article] Hepatocyte growth factor (HGF)2005
- Author(s)
  Ohya W, Funakoshi H, Nakamura T
- Journal Title
  
  Nihon Ronsho 63
  
  Pages: 116-122
- NAID
  10005546016
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Inhibition of apoptosis-inducing factor protective effects of hepatocyte growth factor death in cultured hippocampal neurons.2005
- Author(s)
  Ishihara N, Takagi N, Niimura M, Takagi K, Nakano M, Tanonaka K, Funakoshi H, Matsumoto K, Nakamura T, Takeo S
- Journal Title
  
  J Neurochem 95
  
  Pages: 1277-1286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Effects of fukutin deficiency in the developing mouse brain.2005
- Author(s)
  Chiyonobu Funakoshi, 他6名
- Journal Title
  
  Neuromuscul Disord 15(6)
  
  Pages: 416-426
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Effects of fukutin deficiency in the developing mouse brain.2005
- Author(s)
  T.Chiyonobu, J.Sasaki, Y.Nagai, S.Takeda, H.Funakoshi, T.Nakamura, T.Toda
- Journal Title
  
  Neuromusclar Disorders 15
  
  Pages: 416-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207005
[Journal Article] HGFの神経変性疾患への適用2005
- Author(s)
  船越洋
- Journal Title
  
  Clinical Neurosci. (In press)
- Data Source
  KAKENHI-PROJECT-16015269
[Journal Article] Expression of hepatocyte growth factor in rat skeletal muscle.2005
- Author(s)
  Tanaka S, Tanaka J, Kawahara E, Funakoshi H, Nakamura T, Tachino K
- Journal Title
  
  J Phys Ther Sci 17
  
  Pages: 109-113
- NAID
  10016945664
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Anxiolytic effect of hepatocyte growth factor.2005
- Author(s)
  Isogawa K, Akiyoshi J, Kodama K, Matsushita H, Tsutsumi T, Funakoshi H, Nakamura T
- Journal Title
  
  Neuropsychobiology 51
  
  Pages: 34-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Expression of Hepatocyte Growth Factor in Rat Skeletal Muscle.2005
- Author(s)
  Tanaka S, Funakoshi H, 他4名
- Journal Title
  
  J Phys Ther Sci. 17
  
  Pages: 109-113
- NAID
  10016945664
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] 肝細胞増殖因子(HGF)2005
- Author(s)
  大谷若菜, 船越洋, 中村敏一
- Journal Title
  
  日本臨床 63
  
  Pages: 116-122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Effects of fukutin deficiency in the developing mouse.2005
- Author(s)
  Chiyonobu T, Sasaki J, Nagai Y, Takeda S, Funakoshi H, Nakamura T, Sugimoto T, Toda T
- Journal Title
  
  Neuromuscul Disord 15
  
  Pages: 416-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500241
[Journal Article] Expression of hepatocyte growth factor in rat skeletal muscle.
- Author(s)
  Tanaka S, Tanaka J, Kawahara E, Funakoshi H, Nakamura T, Tachino K
- Journal Title
  
  J Phys Ther Sci. 17
  
  Pages: 109-113
- NAID
  10016945664
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207005
[Presentation] Indoleamine 2,3-dioxygenase predominantly regulates circulating kynurenine levels dependent on plasma tryptophan levels, which are controlled by tryptophan 2,3-dioxygenase, in vivo2012
- Author(s)
  Kanai M., Ohyama F., Tone S., Nakamura T., Funakoshi H.
- Organizer
  The 13th International Society for Tryptophan Research (ISTRY) meeting, Syndey, Australia.
- Place of Presentation
  Syndey, Australia.
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 再生因子（HGF）の神経系における機能と神経再生医療への展開の可能性2012
- Author(s)
  船越洋、島田（大谷）若菜、角山圭一、加藤貴史、中村敏一、北村和也、中村雅也、戸山芳昭、岡野栄之、青木正志
- Organizer
  第19回日本血液代替物学会年次大会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-24500389
[Presentation] HGFは生理的学習機能を亢進する2012
- Author(s)
  船越　洋、加藤　貴史、野間　さつき、金井　将昭1、島田（大谷）若菜、水野　信哉、　土江　信隆、谷口　泰三、角山　圭一、中村　敏一
- Organizer
  厚生労働省班会議
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 再生因子による神経疾患治療法開発を目指して2012
- Author(s)
  船越　洋
- Organizer
  第74回旭川医科大学フォーラム
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] Roles of tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase in higher brain functions2012
- Author(s)
  Funakoshi H, Kanai M., Nakamura T.
- Organizer
  The 13th International Society for Tryptophan Research (ISTRY) meeting,.
- Place of Presentation
  Syndey, Australia.
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 中枢神経におけるHGFは記憶・学習機能を向上させている2011
- Author(s)
  加藤貴史、船越洋、角山圭一、野間さつき、水野信哉、中村敏一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] ヒトトリプトファン2,3-ジオキシゲナーゼの3次元立体構造の同定と精神疾患への意義2011
- Author(s)
  船越　洋、金井将昭、中村敏一
- Organizer
  第422回研究協議会（ビタミンB研究委員会）
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 中枢神経におけるHGF 遺伝子の過剰発現はマウスの記憶・学習機能を向上させる2011
- Author(s)
  加藤貴史、船越洋、角山圭一、野間さつき、金井将昭、島田（大谷）若菜、水野信哉、土江伸誉、谷口泰造、松山正剛、中村敏一.
- Organizer
  中枢神経におけるHGF 遺伝子の過剰発現はマウスの記憶・学習機能を向上させる
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 「こころ」の発達におけるトリプトファン代謝酵素Tryptophan 2,3-dioxygenase の生理的役割2011
- Author(s)
  金井将昭、船越洋、中村敏一
- Organizer
  第84 回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] マウス妊娠初期におけるトリプトファン分解酵素IDO およびTDO の発現.2011
- Author(s)
  大山文男、金井将昭、中村敏一、船越洋、栗林太、刀祢重信
- Organizer
  第33 回トリプトファン研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] マウス妊娠初期におけるトリプトファン分解酵素IDOおよびTDOの発現2011
- Author(s)
  大山文男、金井将昭、中村敏一、船越洋、栗林太、刀禰重信
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] TDO と IDO は異なる機序で循環血液中のキヌレニンレベルを調節する.2011
- Author(s)
  金井将昭、中村敏一、大山文男、刀祢重信、船越洋
- Organizer
  第33 回トリプトファン研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 「こころ」の発達におけるトリプトファン代謝酵素Tryptophan 2,3-dioxygenase の生理的役割2011
- Author(s)
  金井将昭、中村敏一、船越　洋
- Organizer
  第13 回ペット栄養学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] Differential effects on systemic kynurenine levels by tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) under physiological conditions and interferon treatment2011
- Author(s)
  金井将昭、船越洋、中村敏一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] Differential effects on systemic kynurenine levels by TDO and IDO under physiological conditions and interferon treatment.2011
- Author(s)
  T. V. Lanz, P. P. Ho, M. Kanai, H. Funakoshi, T. Nakamura, L. Steinman, W. Wick, and M. Platten
- Organizer
  5th Joint Tri.congress Eur. Ame.Com. Treat.Res.MS.
- Place of Presentation
  オランダ
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] マウス妊娠初期におけるトリプトファン分解酵素IDO およびTDO の発現.2011
- Author(s)
  大山文男、金井将昭、中村敏一、船越洋、栗林太、刀祢重信.
- Organizer
  第84 回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] Differential effects on systemic kynurenine levels by tryptophan 2, 3-dioxygenase(TDO) and indoleamine 2, 3-dioxygenase(IDO) under physiological conditions and interferon treatment2011
- Author(s)
  金井将昭、船越洋、中村敏一
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] TDO と IDO は異なる機序で血中キヌレニン量を調節する.2011
- Author(s)
  金井将昭、中村敏一、船越洋
- Organizer
  第5 回アミノ酸学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] トリプトファン代謝と情動:TDOノックアウトマウスの解析2010
- Author(s)
  船越洋、金井将昭、中村敏一
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] トリプトファン代謝と情動:TDOノックアウトマウスの解析2010
- Author(s)
  船越洋、金井将昭、中村敏一
- Organizer
  第83回日本生化学会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] ALS依存的なHGFによるc-Met/HGF受容体(c-Met)の活性化とその制御機構2010
- Author(s)
  角山圭一、船越洋、島田(大谷)若菜、中村隆弘、松本邦夫、松山正剛、中村敏一
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島国際会議場(広島県)
- Data Source
  KAKENHI-PROJECT-20500295
[Presentation] ALS依存的なHGFによるc-Met/HGF受容体(c-Met)の活性化とその制御機構2010
- Author(s)
  角山圭一、船越洋、島田(大谷)若菜、中村隆弘、松本邦夫、松山正剛、中村敏一
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20500295
[Presentation] Modulation of Tryptophan Metabolism, Promotion of neurogenesis and Alteration of Anxiety-related Behavior in Tryptophan 2,3-Dioxygenase-deficient Mice2009
- Author(s)
  Funakoshi H., et al.
- Organizer
  12nd Meeting of the International Society for Tryptophan Research
- Place of Presentation
  Italy Florence
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] TDO2のミスセンス変異は家族性高トリプトファン血症と情動変化を惹起する2009
- Author(s)
  船越洋
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21390079
[Presentation] Hepatocyte growth factor(HGF)as a novel neurotrophic factor for amyotrophic lateral sclerosis(ALS).2007
- Author(s)
  Funakoshi H.
- Organizer
  17th International Symposium on ALS/MND
- Place of Presentation
  Yokohama
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Presentation] Gene transfer of hepatocyte growth factor (HGF) attenuates behavioral and neuropathological abnormalities in a transgenic mouse model of Huntington's disease2007
- Author(s)
  Funakoshi, H., et. al.
- Organizer
  The 30th Annual Meeting of Japan Neurocience Society
- Year and Date
  2007-09-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Presentation] Gene transfer of hepatocyte growth factor (HGF) attenuates behavioral and neuropathological abnormalities in a transgenic mouse model of Huntington's disease.2007
- Author(s)
  Funakoshi H.
- Organizer
  The 30th Annual Meeting of Japan Neuroscience Society (JNS)
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-18500294
[Presentation] Gene transfer of hepatocyte growth factor(HGF)attenuates behavioral and-neuropathological abnormalities in a transgenic mouse model of Huntington's disease.2007
- Author(s)
  Funakoshi H.
- Organizer
  The 30th Annual Meeting of Japan Neuroscience Society(JNS)
- Place of Presentation
  Yokohama
- Year and Date
  2007-09-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18500294
[Presentation] Hepatocyte growth factor (HGF) as a novel neurotrophic factor for amyotrophic lateral sclerosis (ALS)2007
- Author(s)
  Funakoshi H. & Nakamura T.
- Organizer
  21世紀COEプログラム『疾患関連糖鎖・タンパク質の統合的機能解析』Review Program
- Place of Presentation
  Osaka
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-18500294
[Presentation] トリプトファン代謝と脳機能
- Author(s)
  船越　洋、金井　将昭、中村　敏一
- Organizer
  第31回日本認知症学会学術集会
- Place of Presentation
  茨木
- Invited
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] 再生因子（HGF）の神経系における機能と神経再生医療への展開の可能性（トピックス）
- Author(s)
  船越　洋、中村　敏一
- Organizer
  第19回日本血液代替物学会年次大会
- Place of Presentation
  旭川
- Invited
- Data Source
  KAKENHI-PROJECT-23590362
[Presentation] Hepatocyte growth factor (HGF) as a novel neurotrophic factor for amyotrophic lateral sclerosis (ALS)
- Author(s)
  Funakoshi, H., et. al.
- Organizer
  17th International Symposium on ALS/MND
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18500294

1. NAKAMURA Toshikazu (00049397)

# of Collaborated Projects: 18 results

# of Collaborated Products: 41 results
2. MATSUMOTO Kunio (90201780)

# of Collaborated Projects: 11 results

# of Collaborated Products: 1 results
3. KOSHIMIZU Uichi (50281126)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. MIYAMOTO Kazumasa (60273679)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. MIZUNO Shinya (10219644)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. KADOYAMA Keiichi (70454767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. MATSUYAMA Shogo (80243319)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
8. TANIGUCHI Taizo (70346253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKANO Masaoki (30258107)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. OTANI Mieko (40068284)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 根本康夫 (30250088)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. MATSUMOTO Akira (80181759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. OKA Kiyomasa (70314474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. FUKUTA Kazuhiro (90379264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TANAKA Shoji (70422657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAKAGAWA Takao (40217675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KAWATA Sumio (90183285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MONDEN Morito (00127309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MOCHIZUKI Hideki (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKADA Masahiko (00236233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MIZUNO Yoshikuni (30049043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ADACHI Hiroaki (40432257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SOBUE Gen (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANAKA Fumiaki (30378012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Takakusaki Kaoru (10206732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. OKUMURA Toshikatsu (60281903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NOZU Tsukasa (30312367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OBARA Kazuhiro (40548749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. KOBAYASHI Kazuto (90211903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 原英二 (80263268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 町出充 (90346198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUNAKOSHI Hiroshi 船越 洋

船越 洋 フナコシ ヒロシ

FUNAKOSHI HIROSHI 船越 洋

舟越 洋 フナコシ ヒロシ

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Molecular dissection of tryptophan metabolism in emotional behavior and its related is diseases.Principal Investigator

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Role of HGF in the nervous systemPrincipal Investigator

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HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator

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Neurotrophic role of hepatocytes growth factor (HGF) and its family member in the nervous systemPrincipal Investigator

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HGFおよびそのフアミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator

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HGFおよびそのファミリー因子の作用分子機構の解析と神経変性疾患への適用Principal Investigator

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FUNAKOSHI Hiroshi 船越洋

船越洋フナコシヒロシ

FUNAKOSHI HIROSHI 船越洋

舟越洋フナコシヒロシ